cl 218872 has been researched along with gamma-aminobutyric acid in 24 studies
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
| Studies (cl 218872) | Trials (cl 218872) | Recent Studies (post-2010) (cl 218872) | Studies (gamma-aminobutyric acid) | Trials (gamma-aminobutyric acid) | Recent Studies (post-2010) (gamma-aminobutyric acid) |
|---|---|---|---|---|---|
| 158 | 0 | 3 | 40,215 | 1,423 | 9,631 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (75.00) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 2 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Beer, B; Coupet, J; Greenblatt, EN; Klepner, CA; Lippa, AS | 1 |
| Brouillet, E; Chavoix, C; de la Sayette, V; Guibert, B; Hantraye, P; Khalili-Varasteh, M; Kunimoto, M; Mazière, M; Prenant, C | 1 |
| De Robertis, E; de Stein, ML; Medina, JH | 1 |
| Cortés, R; Palacios, JM; Probst, A; Zezula, J | 1 |
| Arbilla, S; Langer, SZ; Lista, A | 1 |
| Chan, CY; Farb, DH | 1 |
| Cole, R; De Vellis, J; Noble, EP; Syapin, PJ | 1 |
| Meiners, BA; Salama, AI | 1 |
| Garrett, KM; Tabakoff, B | 1 |
| Macdonald, RL; Skerritt, JH | 1 |
| Villiger, JW | 1 |
| Drexler, G; Karobath, M; Sieghart, W; Supavilai, P | 1 |
| Williams, M | 1 |
| Beer, B; Lippa, AS; Meyerson, LR; Sano, MC; Vogel, RA | 1 |
| Malick, JB; Regan, JW; Roeske, WR; Yamamura, HI; Yamamura, SH | 1 |
| Gluckman, PD; Taylor, KM; Villiger, JW | 2 |
| Horst, WD; Kuhar, MJ; Mashal, RD; Niehoff, DL; O'Brien, RA; Palacios, JM | 1 |
| Squires, RF | 1 |
| Carter, DB; Hamilton, BJ; Im, HK; Im, WB; Vonvoigtlander, PF | 1 |
| Akaike, N; Hirata, A; Munakata, M; Shirasaki, T; Yakushiji, T | 1 |
| Aguayo, LG; Cisternas, C; Pancetti, FC; Tapia, JC | 1 |
| Safo, P; Thompson, SA; Wafford, KA; Wheat, L; Whiting, PJ; Wingrove, PB | 1 |
2 review(s) available for cl 218872 and gamma-aminobutyric acid
| Article | Year |
|---|---|
Anxioselective anxiolytics.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety; Azabicyclo Compounds; Benzodiazepines; Brain Chemistry; Drug Interactions; Etazolate; gamma-Aminobutyric Acid; Humans; Molecular Weight; Piperazines; Pyrazoles; Pyridazines; Quinolines; Receptors, Cell Surface; Receptors, GABA-A; Structure-Activity Relationship | 1983 |
Benzodiazepine receptor multiplicity.
Topics: Animals; Brain; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Pyridazines; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
22 other study(ies) available for cl 218872 and gamma-aminobutyric acid
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
A synthetic non-benzodiazepine ligand for benzodiazepine receptors: a probe for investigating neuronal substrates of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Body Temperature; Conflict, Psychological; gamma-Aminobutyric Acid; Glycine; Humans; Ligands; Male; Mice; Motor Activity; Neurons; Pentylenetetrazole; Pyridazines; Rats; Receptors, Drug; Seizures | 1979 |
In vivo benzodiazepine receptor occupancy by CL 218,872 visualized by positron emission tomography in the brain of the living baboon: modulation by GABAergic transmission and relation with anticonvulsant activity.
Topics: Allylglycine; Animals; Anti-Anxiety Agents; Anticonvulsants; Bicuculline; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Occipital Lobe; Papio; Pyridazines; Receptors, GABA-A; Synaptic Transmission; Temporal Lobe; Tomography, Emission-Computed | 1991 |
n-[3H]butyl-beta-carboline-3-carboxylate, a putative endogenous ligand, binds preferentially to subtype 1 of central benzodiazepine receptors.
Topics: Animals; Brain; Carbolines; Cell Nucleus; Cerebral Cortex; Flunitrazepam; gamma-Aminobutyric Acid; Microsomes; Mitochondria; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Membranes | 1989 |
Benzodiazepine receptor sites in the human brain: autoradiographic mapping.
Topics: Aged; Aged, 80 and over; Autoradiography; Brain; Brain Mapping; Female; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Postmortem Changes; Pyridazines; Receptors, GABA-A | 1988 |
Modulation of the electrically evoked release of 5-[3H]hydroxytryptamine from rat cerebral cortex: effects of alpidem, CL 218872, and diazepam.
Topics: Animals; Benzodiazepines; Carbolines; Cerebral Cortex; Diazepam; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Imidazoles; Male; Monoamine Oxidase Inhibitors; Pargyline; Pyrazoles; Pyridazines; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin | 1988 |
Modulation of neurotransmitter action: control of the gamma-aminobutyric acid response through the benzodiazepine receptor.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Carbolines; Chick Embryo; Electric Conductivity; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Neurotransmitter Agents; Picrotoxin; Pyridazines; Receptors, GABA-A | 1985 |
Benzodiazepine binding characteristics of embryonic rat brain neurons grown in culture.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Cells, Cultured; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Neurons; Pyridazines; Rats; Receptors, GABA-A | 1985 |
Enhancement of GABA binding by the benzodiazepine partial agonist CGS9896.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Calcium Chloride; Diazepam; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Pyrazoles; Pyridazines; Rats; Receptors, GABA-A | 1985 |
Effects of prenatal phenobarbital on benzodiazepine receptor development.
Topics: Animals; Brain; Cerebellum; Diencephalon; Female; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Pyridazines; Receptors, GABA-A; Telencephalon | 1986 |
Benzodiazepine receptor ligand actions on GABA responses. Benzodiazepines, CL 218872, zopiclone.
Topics: Animals; Azabicyclo Compounds; Benzodiazepines; Benzodiazepinones; Cells, Cultured; Drug Interactions; Flumazenil; gamma-Aminobutyric Acid; Ligands; Mice; Neurons; Piperazines; Pyridazines; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord | 1984 |
CL 218,872 binding to benzodiazepine receptors in rat spinal cord: modulation by gamma-aminobutyric acid and evidence for receptor heterogeneity.
Topics: Animals; Benzodiazepinones; Cerebral Cortex; Flumazenil; gamma-Aminobutyric Acid; Male; Muscimol; Pyridazines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord | 1984 |
Properties of benzodiazepine receptors in rat retina.
Topics: Animals; Anthelmintics; Anti-Anxiety Agents; Cerebellum; Etazolate; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Ivermectin; Lactones; Molecular Weight; Pyridazines; Rats; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Retina | 1982 |
Differential ontogeny of type 1 and type 2 benzodiazepine receptors.
Topics: Animals; Brain; Female; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Pregnancy; Protein Binding; Pyridazines; Rats; Receptors, Drug; Receptors, GABA-A | 1981 |
gamma-Aminobutyric acid enhancement of CL 218,872 affinity and evidence of benzodiazepine receptor heterogeneity.
Topics: Animals; Bicuculline; Binding, Competitive; Brain; Cattle; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kidney; Kinetics; Pyridazines; Receptors, Drug; Receptors, GABA-A; Retina | 1981 |
Characteristics of type 1 and type 2 benzodiazepine receptors in the ovine brain.
Topics: Animals; Binding, Competitive; Brain; Diazepam; Female; gamma-Aminobutyric Acid; Kinetics; Membranes; Pregnancy; Pyridazines; Receptors, Drug; Receptors, GABA-A; Sheep | 1982 |
Binding of a radiolabeled triazolopyridazine to a subtype of benzodiazepine receptor in the rat cerebellum.
Topics: Animals; Anions; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; Male; Pentobarbital; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A | 1982 |
Multiple benzodiazepine receptors in the ovine brain: ontogenesis, properties, and distribution of 3H-diazepam binding.
Topics: Animals; Brain Chemistry; Diazepam; Female; Fetus; Frontal Lobe; gamma-Aminobutyric Acid; Pyridazines; Receptors, Cell Surface; Receptors, GABA-A; Sheep; Tritium | 1982 |
Potentiation of gamma-aminobutyric acid-induced chloride currents by various benzodiazepine site agonists with the alpha 1 gamma 2, beta 2 gamma 2 and alpha 1 beta 2 gamma 2 subtypes of cloned gamma-aminobutyric acid type A receptors.
Topics: Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Binding Sites; Cells, Cultured; Chloride Channels; Cloning, Molecular; Drug Synergism; Flumazenil; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Imidazoles; Kidney; Kinetics; Membrane Potentials; Piperazines; Pyridazines; Pyridines; Receptors, GABA-A; Triazolam | 1993 |
Differential properties of type I and type II benzodiazepine receptors in mammalian CNS neurones.
Topics: Aging; Animals; Benzothiepins; Central Nervous System; Cerebral Cortex; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neurons; Purkinje Cells; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Tranquilizing Agents | 1993 |
Effects of benzodiazepine receptor ligands on isolated rat superior cervical ganglia neurons.
Topics: Age Factors; Animals; Animals, Newborn; Anti-Anxiety Agents; Diazepam; Electrophysiology; Flumazenil; gamma-Aminobutyric Acid; Ligands; Neurons; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Superior Cervical Ganglion | 1996 |
Mechanism of alpha-subunit selectivity of benzodiazepine pharmacology at gamma-aminobutyric acid type A receptors.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Cell Line; Diazepam; Dose-Response Relationship, Drug; Female; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Mutation; Oocytes; Protein Subunits; Pyridazines; Pyridines; Radioligand Assay; Receptors, GABA-A; Tritium; Xenopus laevis; Zolpidem | 2002 |