cki 7 and d 4476
cki 7 has been researched along with d 4476 in 5 studies
Compound Research Comparison
| Studies (cki 7) | Trials (cki 7) | Recent Studies (post-2010) (cki 7) | Studies (d 4476) | Trials (d 4476) | Recent Studies (post-2010) (d 4476) |
|---|---|---|---|---|---|
| 35 | 0 | 7 | 18 | 0 | 13 |
Protein Interaction Comparison
| Protein | Taxonomy | cki 7 (IC50) | d 4476 (IC50) |
|---|---|---|---|
| TGF-beta receptor type-1 | Homo sapiens (human) | 0.5 | |
| Casein kinase II subunit alpha | Schizosaccharomyces pombe 972h- | 0.2 | |
| Casein kinase I isoform alpha | Homo sapiens (human) | 0.3 | |
| Casein kinase I isoform delta | Homo sapiens (human) | 0.2678 | |
| Casein kinase I isoform epsilon | Homo sapiens (human) | 0.319 | |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | 0.3 | |
| Casein kinase I isoform delta | Rattus norvegicus (Norway rat) | 0.3267 | |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | 9.1 | |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 4.977 | |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | 0.3 |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N | 1 |
| Caparrotta, L; Cozza, G; Gianoncelli, A; Meggio, F; Montopoli, M; Moro, S; Pinna, LA; Venerando, A; Zagotto, G | 1 |
| Abadleh, M; Bischof, J; Hauser, D; Hirner, H; Knippschild, U; Laufer, S; Peifer, C; Schattel, V | 1 |
| Feng, S; Ji, P; Li, GB; Ma, S; Sun, QZ; Wang, ZR; Yan, HX; Yang, LL; Yang, SY; Zou, J | 1 |
| Chen, T; Chen, Y; Feng, F; Guo, Q; Lin, H; Liu, W; Liu, Z; Qiao, Y; Qu, W; Sun, H; Yang, H | 1 |
Reviews
1 review(s) available for cki 7 and d 4476
| Article | Year |
|---|---|
Small molecule modulators targeting protein kinase CK1 and CK2.
Topics: Animals; Casein Kinase I; Casein Kinase II; Drug Discovery; Humans; Molecular Docking Simulation; Protein Kinase Inhibitors; Small Molecule Libraries | 2019 |
Other Studies
4 other study(ies) available for cki 7 and d 4476
| Article | Year |
|---|---|
The selectivity of protein kinase inhibitors: a further update.
Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera | 2007 |
Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening.
Topics: Anthraquinones; Casein Kinase I; Chemistry, Pharmaceutical; Computer Simulation; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Molecular Conformation; Phosphorylation; Protein Isoforms; Software; Tyrosine | 2008 |
3,4-Diaryl-isoxazoles and -imidazoles as potent dual inhibitors of p38alpha mitogen activated protein kinase and casein kinase 1delta.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding, Competitive; Casein Kinase Idelta; Cell Line; Drug Discovery; Enzyme Inhibitors; Humans; Imidazoles; Inhibitory Concentration 50; Isoxazoles; Mitogen-Activated Protein Kinase 14; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Rats; Trophoblasts | 2009 |
Discovery of N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine derivatives as novel CK1 inhibitors using common-feature pharmacophore model based virtual screening and hit-to-lead optimization.
Topics: Casein Kinase I; Diamines; Dose-Response Relationship, Drug; Drug Discovery; High-Throughput Screening Assays; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Pyrimidines; Structure-Activity Relationship | 2012 |