cki 7 has been researched along with 4-(3-cyclohexyl-5-(4-fluoro-phenyl)-3h-imidazol-4-yl)pyrimidin-2-ylamine in 2 studies
| Studies (cki 7) | Trials (cki 7) | Recent Studies (post-2010) (cki 7) | Studies (4-(3-cyclohexyl-5-(4-fluoro-phenyl)-3h-imidazol-4-yl)pyrimidin-2-ylamine) | Trials (4-(3-cyclohexyl-5-(4-fluoro-phenyl)-3h-imidazol-4-yl)pyrimidin-2-ylamine) | Recent Studies (post-2010) (4-(3-cyclohexyl-5-(4-fluoro-phenyl)-3h-imidazol-4-yl)pyrimidin-2-ylamine) |
|---|---|---|---|---|---|
| 35 | 0 | 7 | 13 | 0 | 12 |
| Protein | Taxonomy | cki 7 (IC50) | 4-(3-cyclohexyl-5-(4-fluoro-phenyl)-3h-imidazol-4-yl)pyrimidin-2-ylamine (IC50) |
|---|---|---|---|
| Chain A, Casein kinase I isoform delta | Homo sapiens (human) | 0.014 | |
| Chain A, Casein kinase I isoform delta | Homo sapiens (human) | 0.013 | |
| Chain A, Casein kinase I isoform epsilon | Homo sapiens (human) | 0.013 | |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | 0.0392 | |
| Epidermal growth factor receptor | Homo sapiens (human) | 0.15 | |
| Gonadotropin-releasing hormone receptor | Homo sapiens (human) | 0.13 | |
| Casein kinase I isoform delta | Homo sapiens (human) | 0.031 | |
| Casein kinase I isoform epsilon | Homo sapiens (human) | 0.0524 | |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | 0.0392 | |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | 0.0392 | |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 0.1146 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, S; Ji, P; Li, GB; Ma, S; Sun, QZ; Wang, ZR; Yan, HX; Yang, LL; Yang, SY; Zou, J | 1 |
| Chen, T; Chen, Y; Feng, F; Guo, Q; Lin, H; Liu, W; Liu, Z; Qiao, Y; Qu, W; Sun, H; Yang, H | 1 |
1 review(s) available for cki 7 and 4-(3-cyclohexyl-5-(4-fluoro-phenyl)-3h-imidazol-4-yl)pyrimidin-2-ylamine
| Article | Year |
|---|---|
Small molecule modulators targeting protein kinase CK1 and CK2.
Topics: Animals; Casein Kinase I; Casein Kinase II; Drug Discovery; Humans; Molecular Docking Simulation; Protein Kinase Inhibitors; Small Molecule Libraries | 2019 |
1 other study(ies) available for cki 7 and 4-(3-cyclohexyl-5-(4-fluoro-phenyl)-3h-imidazol-4-yl)pyrimidin-2-ylamine
| Article | Year |
|---|---|
Discovery of N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine derivatives as novel CK1 inhibitors using common-feature pharmacophore model based virtual screening and hit-to-lead optimization.
Topics: Casein Kinase I; Diamines; Dose-Response Relationship, Drug; Drug Discovery; High-Throughput Screening Assays; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Pyrimidines; Structure-Activity Relationship | 2012 |