citrulline and tissue plasminogen activator

citrulline has been researched along with tissue plasminogen activator in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (55.17)18.2507
2000's12 (41.38)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frey, C; Griffith, OW; Masters, BS; McMillan, K; Salerno, JC; Williams, RF1
Griffith, OW; Narayanan, K1
Frey, C; Griffith, OW; Gross, SS; Masters, BS; McMillan, K; Narayanan, K; Spack, L1
Abu-Soud, HM; Clark, P; Feldman, PL; Stuehr, DJ1
Griffith, OW; Joly, GA; Kilbourn, RG; Narayanan, K1
Griffith, OW; Kilbourn, RG1
Gozal, D; Gozal, YM; Littwin, SM; Torres, JE1
García-Cardeña, G; Nathan, CF; Sessa, WC; Smith, SD; Weiss, RM; Wheeler, MA1
Evans, CH; Miller, LA; Möllers, MO; Stefanovic-Racic, M1
Dick, JM; Lefebvre, RA1
Arvai, AS; Crane, BR; Getzoff, ED; Ghosh, DK; Stuehr, DJ; Tainer, JA; Wu, C1
Chu, Y; Faraci, FM; Gunnett, CA; Heistad, DD; Loihl, A1
D'Agostino, PA; Hancock, JR; Sawyer, TW1
Sawyer, TW1
Ball, AK; Koeberle, PD1
Béani, JC; Cadet, J; Didier, C; Emonet-Piccardi, N; Richard, MJ1
Risk, D; Sawyer, TW1
Costa, G; García-Pascual, A; Jiménez, E; Labadía, A; Triguero, D1
Baeza-Squiban, A; Calvet, J; Marano, F; Rappeneau, S1
King, SB; Ware, RW1
González, MP; Oset-Gasque, MJ; Vicente, S1
Sagami, I; Shimizu, T; Yadav, J1
Ellis, ZM; Haque, SM; Kellum, JM; King, BN; Stoner, MC1
Chinje, EC; Goodyer, CL; Jaffar, M; Stratford, IJ; Threadgill, MD1
Dechant, G; Humpel, C; Zassler, B1
Baguet, F; Holmgren, S; Krönström, J; Mallefet, J; Salpietro, L1
Goodman, RL; Hardy, SL; McManus, CJ; Valent, M1
Costa, G; García-Pascual, A; González-Herreros, M; Triguero, D1
Ehrlich, D; Humpel, C; Pirchl, M1

Other Studies

29 other study(ies) available for citrulline and tissue plasminogen activator

ArticleYear
Characterization by electron paramagnetic resonance of the interactions of L-arginine and L-thiocitrulline with the heme cofactor region of nitric oxide synthase.
    The Journal of biological chemistry, 1995, Nov-17, Volume: 270, Issue:46

    Topics: Animals; Arginine; Binding Sites; Cell Line; Citrulline; Electron Spin Resonance Spectroscopy; Heme; Kidney; Nitric Oxide Synthase; Protein Conformation; Rats; Recombinant Proteins; Thermodynamics; Thiourea; Transfection

1995
Synthesis of L-thiocitrulline, L-homothiocitrulline, and S-methyl-L-thiocitrulline: a new class of potent nitric oxide synthase inhibitors.
    Journal of medicinal chemistry, 1994, Apr-01, Volume: 37, Issue:7

    Topics: Amino Acid Oxidoreductases; Aminocaproates; Aminocaproic Acid; Animals; Binding Sites; Brain; Citrulline; Heme; Iron; Muscle, Smooth; Nitric Oxide Synthase; Rats; Thiourea

1994
L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthases.
    The Journal of biological chemistry, 1994, Oct-21, Volume: 269, Issue:42

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding Sites; Citrulline; Cytochrome c Group; Heme; Kinetics; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Thiourea

1994
Electron transfer in the nitric-oxide synthases. Characterization of L-arginine analogs that block heme iron reduction.
    The Journal of biological chemistry, 1994, Dec-23, Volume: 269, Issue:51

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Transport; Cells, Cultured; Citrulline; Cloning, Molecular; Electrons; Heme; Humans; Iron; Kinetics; NADP; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Rats; Thiourea

1994
Characterization of the effects of two new arginine/citrulline analogues on constitutive and inducible nitric oxide synthases in rat aorta.
    British journal of pharmacology, 1995, Volume: 115, Issue:3

    Topics: Acetylcholine; Adenosine Diphosphate; Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Calcimycin; Citrulline; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Ionophores; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar; Thiourea; Vasoconstrictor Agents

1995
Nitric oxide synthase inhibitors: amino acids.
    Methods in enzymology, 1996, Volume: 268

    Topics: Amino Acids; Animals; Arginine; Citrulline; Enzyme Inhibitors; Isoenzymes; Kinetics; Macrophages; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rodentia; Structure-Activity Relationship; Thiourea

1996
Effect of nitric oxide synthase inhibition on cardiorespiratory responses in the conscious rat.
    Journal of applied physiology (Bethesda, Md. : 1985), 1996, Volume: 81, Issue:5

    Topics: Animals; Blood Gas Analysis; Blood Pressure; Citrulline; Enzyme Inhibitors; Heart Rate; Hemodynamics; Hypercapnia; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Thiourea

1996
Bacterial infection induces nitric oxide synthase in human neutrophils.
    The Journal of clinical investigation, 1997, Jan-01, Volume: 99, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Arginine; Bacterial Infections; Blotting, Western; Canavanine; Cell Membrane; Citrulline; Female; Guanidines; Humans; Immunohistochemistry; Isoenzymes; Leukocyte Common Antigens; Male; Middle Aged; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thiourea; Trifluoperazine; Urinary Tract Infections

1997
Nitric oxide and proteoglycan turnover in rabbit articular cartilage.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1997, Volume: 15, Issue:3

    Topics: Animals; Cartilage, Articular; Citrulline; Enzyme Inhibitors; Heme; Interleukin-1; Metalloendopeptidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Proteoglycans; Rabbits; Superoxides; Thiourea

1997
Influence of different classes of NO synthase inhibitors in the pig gastric fundus.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:4

    Topics: Animals; Biotin; Citrulline; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; In Vitro Techniques; Isothiuronium; Lysine; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Ornithine; Swine; Thiourea

1997
Structure of nitric oxide synthase oxygenase dimer with pterin and substrate.
    Science (New York, N.Y.), 1998, Mar-27, Volume: 279, Issue:5359

    Topics: Animals; Arginine; Binding Sites; Biopterins; Citrulline; Crystallography, X-Ray; Dimerization; Hydrogen Bonding; Isoenzymes; Ligands; Macrophages; Mice; Models, Molecular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Conformation; Protein Folding; Protein Structure, Secondary; Thiourea

1998
Vascular effects of LPS in mice deficient in expression of the gene for inducible nitric oxide synthase.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carotid Arteries; Citrulline; Dinoprost; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanidines; Heterozygote; In Vitro Techniques; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger; Thiourea; Transcription, Genetic; Vasoconstriction

1998
l-thiocitrulline: A potent protective agent against the toxicity of sulphur mustard in vitro.
    Toxicology and applied pharmacology, 1998, Volume: 151, Issue:2

    Topics: Animals; Antidotes; Chemical Warfare Agents; Chick Embryo; Chickens; Citrulline; Enzyme Inhibitors; Mustard Gas; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Thiourea

1998
Synergistic protective effects of selected arginine analogues against sulphur mustard toxicity in neuron culture.
    Toxicology and applied pharmacology, 1999, Mar-01, Volume: 155, Issue:2

    Topics: Animals; Arginine; Carcinogens; Cells, Cultured; Chick Embryo; Citrulline; Drug Synergism; Mustard Gas; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Thiourea

1999
Nitric oxide synthase inhibition delays axonal degeneration and promotes the survival of axotomized retinal ganglion cells.
    Experimental neurology, 1999, Volume: 158, Issue:2

    Topics: Animals; Axons; Axotomy; Cell Survival; Citrulline; Dihydrolipoamide Dehydrogenase; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Injections; Lysine; Nerve Degeneration; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitroarginine; Optic Nerve; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Thiourea; Time Factors

1999
L-arginine increases UVA cytotoxicity in irradiated human keratinocyte cell line: potential role of nitric oxide.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:13

    Topics: Antioxidants; Arginine; Catalase; Cell Line; Cell Survival; Citrulline; DNA Damage; Humans; Keratinocytes; Metalloproteins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Penicillamine; Poly(ADP-ribose) Polymerases; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Thiourea; Ultraviolet Rays

1999
Effects of selected arginine analogues on sulphur mustard toxicity in human and hairless guinea pig skin keratinocytes.
    Toxicology and applied pharmacology, 2000, Feb-15, Volume: 163, Issue:1

    Topics: Administration, Topical; Animals; Arginine; Cells, Cultured; Citrulline; Dermatologic Agents; Enzyme Inhibitors; Guinea Pigs; Humans; Keratinocytes; Mustard Gas; NG-Nitroarginine Methyl Ester; Nitroarginine; Organophosphorus Compounds; Skin; Thiourea

2000
Spontaneous photo-relaxation of urethral smooth muscle from sheep, pig and rat and its relationship with nitrergic neurotransmission.
    The Journal of physiology, 2000, Feb-01, Volume: 522 Pt 3

    Topics: Adenine; Animals; Citrulline; Cold Temperature; Culture Techniques; Electric Stimulation; Enzyme Inhibitors; Female; Light; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Oxadiazoles; Oxyhemoglobins; Phosphodiesterase Inhibitors; Photic Stimulation; Potassium; Purinones; Quinoxalines; Rats; Rats, Wistar; Sheep; Superoxides; Swine; Synaptic Transmission; Tetrodotoxin; Thiourea; Time Factors; Urethra

2000
Efficient protection of human bronchial epithelial cells against sulfur and nitrogen mustard cytotoxicity using drug combinations.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 58, Issue:1

    Topics: Acetylcysteine; Bronchi; Cells, Cultured; Citrulline; Cytoprotection; Dose-Response Relationship, Drug; Doxycycline; Drug Combinations; Drug Interactions; Epithelial Cells; Humans; Mechlorethamine; Mercaptoethylamines; Methenamine; Mustard Gas; NG-Nitroarginine Methyl Ester; Niacinamide; Protective Agents; Radiation-Protective Agents; Tetrazolium Salts; Thiourea

2000
Evaluation of new L-thiocitrulline derivatives as inhibitors of nitric oxide synthase.
    Bioorganic & medicinal chemistry letters, 2000, Dec-18, Volume: 10, Issue:24

    Topics: Animals; Binding Sites; Cattle; Citrulline; Enzyme Inhibitors; Isoenzymes; Kinetics; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Structure-Activity Relationship; Thiourea

2000
Neuronal nitric oxide synthase modulates basal catecholamine secretion in bovine chromaffin cells.
    Journal of neuroscience research, 2002, Aug-01, Volume: 69, Issue:3

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Blotting, Western; Catecholamines; Cattle; Cell Culture Techniques; Chromaffin Cells; Citrulline; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Guanylate Cyclase; Isoenzymes; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phosphodiesterase Inhibitors; Purinones; Thiourea; Time Factors

2002
Cyanide binding study of neuronal nitric oxide synthase: effects of inhibitors and mutations at the substrate binding site.
    Journal of inorganic biochemistry, 2003, May-01, Volume: 95, Issue:1

    Topics: Arginine; Binding Sites; Citrulline; Cyanides; Enzyme Inhibitors; Indazoles; Mutagenesis, Site-Directed; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Spectrophotometry, Ultraviolet; Thiourea

2003
Inhibition of neural nitric oxide synthase attenuates the chloride secretory response to stroking in human jejunum.
    Surgery, 2003, Volume: 134, Issue:2

    Topics: Chlorides; Citrulline; Electric Conductivity; Enzyme Inhibitors; Humans; In Vitro Techniques; Jejunum; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Physical Stimulation; Serotonin; Thiourea

2003
Time-dependence and preliminary SAR studies in inhibition of nitric oxide synthase isoforms by homologues of thiocitrulline.
    Bioorganic & medicinal chemistry letters, 2003, Nov-03, Volume: 13, Issue:21

    Topics: Animals; Citrulline; Enzyme Inhibitors; Humans; Indicators and Reagents; Isoenzymes; Kinetics; Magnetic Resonance Spectroscopy; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Thiourea

2003
Urea enhances the nerve growth factor-induced neuroprotective effect on cholinergic neurons in organotypic rat brain slices.
    Neuroscience, 2005, Volume: 130, Issue:2

    Topics: Animals; Animals, Newborn; Basal Nucleus of Meynert; Cell Survival; Choline O-Acetyltransferase; Cholinergic Fibers; Citrulline; Drug Synergism; Enzyme Inhibitors; Nerve Growth Factor; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Organ Culture Techniques; PC12 Cells; Protein Binding; Rats; Thiourea; Urea

2005
Nitric oxide in control of luminescence from hatchetfish (Argyropelecus hemigymnus) photophores.
    The Journal of experimental biology, 2005, Volume: 208, Issue:Pt 15

    Topics: Animals; Avidin; Biotin; Citrulline; Epinephrine; Fishes; Hydroxylamine; Immunohistochemistry; Luminescence; Luminescent Proteins; Nitric Oxide; Nitroprusside; S-Nitroso-N-Acetylpenicillamine; Thiourea

2005
Does nitric oxide act in the ventromedial preoptic area to mediate oestrogen negative feedback in the seasonally anoestrous ewe?
    Reproduction (Cambridge, England), 2007, Volume: 134, Issue:1

    Topics: Anestrus; Animals; Citrulline; Drug Implants; Estrogens; Feedback, Physiological; Female; Luteinizing Hormone; Microinjections; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Preoptic Area; Seasons; Sheep; Stimulation, Chemical; Thiourea

2007
Localization and thiol dependancy of endogenous nitro compounds-mediating urethral photo-relaxation.
    Pflugers Archiv : European journal of physiology, 2008, Volume: 455, Issue:4

    Topics: Animals; Animals, Newborn; Buthionine Sulfoximine; Citrulline; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Ethacrynic Acid; Female; Fluoresceins; Fluorescent Dyes; Glutathione; In Vitro Techniques; Light; Microscopy, Fluorescence; Muscle Relaxation; Muscle, Smooth; Nitrergic Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Photolysis; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; S-Nitrosoglutathione; Sheep; Sulfhydryl Compounds; Thiazolidines; Thiourea; Urethra

2008
Ethanol transiently suppresses choline-acetyltransferase in basal nucleus of Meynert slices.
    Brain research, 2012, Jun-12, Volume: 1459

    Topics: Analysis of Variance; Animals; Animals, Newborn; Basal Nucleus of Meynert; Central Nervous System Depressants; Chemokine CXCL2; Choline O-Acetyltransferase; Citrulline; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Enzyme Inhibitors; Ethanol; Imidazoles; In Vitro Techniques; Nerve Growth Factor; Neurons; Pyridines; Rats; Thiourea; Time Factors; Tumor Necrosis Factor-alpha

2012