citrulline and myelin basic protein

citrulline has been researched along with myelin basic protein in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.00)18.7374
1990's19 (38.00)18.2507
2000's20 (40.00)29.6817
2010's9 (18.00)24.3611
2020's1 (2.00)2.80

Authors

AuthorsStudies
Goodin, RR; Herman, PK; Kirk, KA; Moscarello, MA; Whitaker, JN; Wood, DD; Zhou, SR1
McLaurin, J; Moscarello, MA2
Moscarello, MA; Wood, DD1
Moscarello, MA; Whitaker, JN; Zhou, SR1
Goodin, RR; Martin, R; McFarland, HF; Rhame, L; Whitaker, JN1
el-Fakahany, EE; Fridlund, J; Hu, J1
Boulias, C; Mastronardi, F; Moscarello, MA; Pang, H1
Boggs, JM; Koshy, KM1
Moscarello, MA; Tompkins, TA1
Moscarello, MA; Whitaker, JN; Wood, DD; Zhou, SR1
Lamensa, JW; Moscarello, MA1
Ackerley, CA; McLaurin, J; Moscarello, MA1
Ackerley, CA; Mak, B; Mastronardi, FG; Moscarello, MA; Roots, BI1
Ackerley, CA; Groome, N; Mastronardi, FG; Moscarello, MA; Yon, M1
Bilbao, JM; Moscarello, MA; O'Connors, P; Wood, DD1
Cao, L; Sun, D; Whitaker, JN1
Cao, L; Goodin, R; Moscarello, MA; Whitaker, JN; Wood, D1
Beniac, DR; Harauz, G; Moscarello, MA; Ottensmeyer, FP; Palaniyar, N; Wood, DD2
Ackerley, C; Boggs, JM; Koshy, KM; Moscarello, MA; Rangaraj, G; Wood, DD1
Asou, H; Iguchi, T; Seiwa, C; Sugiyama, I; Yagi, T1
Gowan, JJ; Harauz, G; Joshi, S; Moscarello, MA; Pritzker, LB1
Harauz, G; Joshi, S; Moscarello, MA; Pritzker, LB1
Cao, L; Kalbacher, H; Ling, NC; Martin, RM; Tranquill, LR; Whitaker, JN1
de Seze, J; Dubucquoi, S; Dutoit, V; Lefranc, D; Nuez, I; Prin, L; Vermersch, P; Virecoulon, F1
Mastronardi, FG; Moscarello, MA; Pritzker, L; Wood, DD1
Echols, JD; Gupta, KB; King, JL; McInnis, C; Nicholas, AP; Sambandam, T; Whitaker, JN1
Armstrong, S; Bates, IR; Hallett, FR; Harauz, G; Hill, CM; Libich, DS; Siemiarczuk, A1
Bates, IR; Boggs, JM; Harauz, G; Heng, YM; Hill, CM; Rangaraj, G1
Barnum, SR; Echols, JD; Nicholas, AP; Sambandam, T1
Caponi, L; Cornelis, F; Cournu-Rebeix, I; Fontaine, B; Migliorini, P; Petit-Teixeira, E; Pierlot, C; Tommasi, C1
Harauz, G; Musse, AA1
Mastronardi, FG; Moscarello, MA; Wood, DD1
Mastronardi, FG; Moscarello, MA; Noor, A; Paton, T; Wood, DD1
Ackerley, CA; Brand, Bv; Mastronardi, FG; Moscarello, MA; Raijmakers, R; Wood, DD; Zhang, L1
Carp, RI; Choi, EK; Choi, JK; Ishigami, A; Jang, B; Jin, JK; Kim, E; Kim, JI; Kim, YS; Maruyama, N1
Apostolopoulos, V; Chatzantoni, K; Deraos, G; Deraos, S; Katsara, M; Matsoukas, J; Matsoukas, MT; Mouzaki, A; Papathanasopoulos, P; Tselios, T; Vynios, D1
Aksu, AO; Anlar, B; Haspolat, S; Karabulut, E; Kurne, A; Kurul, S; Oguz, KK; Senbil, N; Serdaroglu, A; Teber, S1
Fleckenstein, B; Holm, A; Kiehne, A; Stensland, M1
Fleckenstein, B; Holm, A; Jørgensen, M; Rise, F; Stadtmüller, P; Tutturen, AE1
Kalandadze, IV; Mikeladze, DG; Ramsden, JJ; Shanshiashvili, LV1
Koch, MW; Kovalchuk, O; Metz, LM1
Baeten, D; Cantaert, T; Tak, PP; Teitsma, C1
Everett, AD; Fu, Z; Jin, Z; Troncosco, J; Van Eyk, JE; Yang, J1
Fleckenstein, B; Holm, A; Tutturen, AE1
Alpayci, M; Aydin, MN; Bayram, Y; Delen, V; Guducuoglu, H; Milanlioglu, A1
Piao, H; Tan, D; Yang, L1
Beelen, R; D'haeseleer, M; De Keyser, J; Nagels, G; Van Binst, AM; Vande Vyver, M; Verborgh, C1
Grund, EM; Howe, CL; Standiford, MM1

Reviews

4 review(s) available for citrulline and myelin basic protein

ArticleYear
A tale of two citrullines--structural and functional aspects of myelin basic protein deimination in health and disease.
    Neurochemical research, 2007, Volume: 32, Issue:2

    Topics: Amino Acid Sequence; Animals; Arthritis, Rheumatoid; Citrulline; Humans; Hydrolases; Molecular Sequence Data; Multiple Sclerosis; Myelin Basic Protein; Myelin Sheath; Protein Conformation; Protein Processing, Post-Translational; Protein-Arginine Deiminases

2007
The role of citrullinated proteins suggests a novel mechanism in the pathogenesis of multiple sclerosis.
    Neurochemical research, 2007, Volume: 32, Issue:2

    Topics: Apoptosis; Citrulline; Humans; Hydrolases; Methylation; Multiple Sclerosis; Myelin Basic Protein; Oligodendroglia; Protein Conformation; Protein Processing, Post-Translational; Protein-Arginine Deiminases

2007
Epigenetic changes in patients with multiple sclerosis.
    Nature reviews. Neurology, 2013, Volume: 9, Issue:1

    Topics: Citrulline; Disease Progression; DNA Methylation; Epigenesis, Genetic; Forecasting; Gene-Environment Interaction; Histone Deacetylase Inhibitors; Humans; Inflammation Mediators; Lymphocyte Activation; Macrophage Activation; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Myelin Basic Protein; Neurotransmitter Agents; Oligonucleotides; Risk Factors; T-Lymphocytes, Helper-Inducer

2013
Myelin Basic Protein Citrullination in Multiple Sclerosis: A Potential Therapeutic Target for the Pathology.
    Neurochemical research, 2016, Volume: 41, Issue:8

    Topics: Animals; Citrulline; Drug Delivery Systems; Humans; Hydrolases; Immunologic Factors; Multiple Sclerosis; Myelin Basic Protein; Neuroprotective Agents; Protein-Arginine Deiminases

2016

Trials

1 trial(s) available for citrulline and myelin basic protein

ArticleYear
Assessment of citrullinated myelin by 1H-MR spectroscopy in early-onset multiple sclerosis.
    AJNR. American journal of neuroradiology, 2009, Volume: 30, Issue:4

    Topics: Adolescent; Age of Onset; Aspartic Acid; Child; Child, Preschool; Choline; Citrulline; Creatine; Demyelinating Diseases; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Multiple Sclerosis, Relapsing-Remitting; Myelin Basic Protein; Myelin Sheath; Protons; Young Adult

2009

Other Studies

45 other study(ies) available for citrulline and myelin basic protein

ArticleYear
An immunochemical comparison of human myelin basic protein and its modified, citrullinated form, C8.
    Journal of neuroimmunology, 1992, Volume: 36, Issue:2-3

    Topics: Adult; Animals; Citrulline; Humans; Immunochemistry; Myelin Basic Protein; Protein Processing, Post-Translational; Rabbits; Sheep

1992
Reactivity of two anti-galactosyl ceramide antibodies towards myelin basic protein.
    Journal of the neurological sciences, 1992, Volume: 108, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Cattle; Ceramides; Citrulline; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Epitopes; Galactose; Galactosylceramides; Immunoglobulin G; Liposomes; Mice; Myelin Basic Protein; Peptides; Rabbits; Structure-Activity Relationship

1992
The preparation of antibodies reactive against citrulline-containing charge isomers of myelin basic protein but not against the arginine-containing charge isomers.
    Analytical biochemistry, 1990, Volume: 191, Issue:2

    Topics: Amino Acid Sequence; Antibodies; Antibody Specificity; Arginine; Calorimetry, Differential Scanning; Chromatography, Thin Layer; Citrulline; Humans; Isomerism; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Myelin Basic Protein; Spectrometry, Mass, Fast Atom Bombardment

1990
The isolation, characterization, and lipid-aggregating properties of a citrulline containing myelin basic protein.
    The Journal of biological chemistry, 1989, Mar-25, Volume: 264, Issue:9

    Topics: Amino Acid Sequence; Chromatography, Ion Exchange; Citrulline; Humans; Isomerism; Middle Aged; Molecular Sequence Data; Myelin Basic Protein; Myelin Proteins; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Proteolipids; Uteroglobin

1989
The effects of citrullination or variable amino-terminus acylation on the encephalitogenicity of human myelin basic protein in the PL/J mouse.
    Journal of neuroimmunology, 1995, Volume: 62, Issue:2

    Topics: Acylation; Animals; Citrulline; Encephalomyelitis, Autoimmune, Experimental; Humans; Mice; Myelin Basic Protein; Protein Processing, Post-Translational; Structure-Activity Relationship

1995
Citrulline-containing myelin basic protein is recognized by T-cell lines derived from multiple sclerosis patients and healthy individuals.
    Neurology, 1994, Volume: 44, Issue:1

    Topics: Adult; Amino Acid Sequence; Antigen-Presenting Cells; Cell Line; Citrulline; Female; Humans; Lymphocyte Activation; Male; Middle Aged; Molecular Sequence Data; Multiple Sclerosis; Myelin Basic Protein; Reference Values; Stereoisomerism; T-Lymphocytes

1994
Regulation of neuronal nitric oxide synthase by histone, protamine, and myelin basic protein.
    Neurochemical research, 1995, Volume: 20, Issue:4

    Topics: Amino Acid Oxidoreductases; Animals; Binding, Competitive; Calcium; Citrulline; Cyclic GMP; Cytosol; Histones; Myelin Basic Protein; Nerve Tissue Proteins; Neuroblastoma; Neurons; Nitric Oxide Synthase; Protamines; Rats; Stimulation, Chemical; Tumor Cells, Cultured

1995
The isolation and characterization of four myelin basic proteins from the unbound fraction during CM52 chromatography.
    Archives of biochemistry and biophysics, 1995, Sep-10, Volume: 322, Issue:1

    Topics: Amino Acid Sequence; Amino Acids; Brain Chemistry; Chromatography, Ion Exchange; Citrulline; Electrochemistry; Humans; Mass Spectrometry; Molecular Sequence Data; Molecular Weight; Myelin Basic Protein; Peptide Fragments

1995
Interference of carbohydrates in the quantitation of protein-bound citrulline by amino acid analysis.
    Analytical biochemistry, 1993, Feb-01, Volume: 208, Issue:2

    Topics: Amino Acids; Carbohydrates; Chromatography, Gel; Chromatography, Ion Exchange; Citrulline; Electrophoresis, Polyacrylamide Gel; Evaluation Studies as Topic; Humans; Hydrolysis; Myelin Basic Protein; Protein Binding

1993
Stimulation of bovine brain phospholipase C activity by myelin basic protein requires arginyl residues in peptide linkage.
    Archives of biochemistry and biophysics, 1993, Volume: 302, Issue:2

    Topics: Animals; Arginine; Brain; Cattle; Citrulline; Hydrolases; Myelin Basic Protein; Peptides; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Polylysine; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Sequence Analysis; Structure-Activity Relationship; Trypsin

1993
Immunological analysis of the amino terminal and the C8 isomer of human myelin basic protein.
    Journal of neuroimmunology, 1993, Volume: 46, Issue:1-2

    Topics: Acylation; Antibodies, Monoclonal; Citrulline; Epitopes; Humans; Lymphocyte Activation; Myelin Basic Protein; Peptides; Protein Processing, Post-Translational; Structure-Activity Relationship

1993
Deimination of human myelin basic protein by a peptidylarginine deiminase from bovine brain.
    Journal of neurochemistry, 1993, Volume: 61, Issue:3

    Topics: Amino Acid Sequence; Animals; Brain; Calcium; Cattle; Circular Dichroism; Citrulline; Humans; Hydrolases; Imines; Immunochemistry; Molecular Sequence Data; Myelin Basic Protein; Peptides; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Temperature

1993
Localization of basic proteins in human myelin.
    Journal of neuroscience research, 1993, Aug-15, Volume: 35, Issue:6

    Topics: Amino Acid Sequence; Brain; Brain Chemistry; Citrulline; Enzyme-Linked Immunosorbent Assay; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Molecular Sequence Data; Myelin Basic Protein; Protein Processing, Post-Translational; Synaptic Vesicles

1993
Modifications of myelin basic protein in DM20 transgenic mice are similar to those in myelin basic protein from multiple sclerosis.
    The Journal of clinical investigation, 1996, Jan-15, Volume: 97, Issue:2

    Topics: Animals; Citrulline; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Gene Dosage; Hydrolases; Isoelectric Point; Mice; Mice, Mutant Strains; Mice, Transgenic; Multiple Sclerosis; Myelin Basic Protein; Myelin Proteolipid Protein; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases

1996
Identification of a mitogen-activated protein kinase site in human myelin basic protein in situ.
    Journal of neuroimmunology, 1996, Volume: 65, Issue:1

    Topics: Amino Acid Sequence; Antibody Specificity; Binding Sites; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Citrulline; Humans; Immunohistochemistry; Microscopy, Electron; Mitogens; Molecular Sequence Data; Multiple Sclerosis; Myelin Basic Protein; Myelin Sheath; Phosphorylation; Threonine

1996
Acute multiple sclerosis (Marburg type) is associated with developmentally immature myelin basic protein.
    Annals of neurology, 1996, Volume: 40, Issue:1

    Topics: Adult; Antibodies, Monoclonal; Arginine; Blotting, Western; Brain; Brain Chemistry; Chronic Disease; Citrulline; Demyelinating Diseases; Fatal Outcome; Female; Humans; Lymphocytes; Macrophages; Magnetic Resonance Imaging; Multiple Sclerosis; Myelin Basic Protein

1996
Citrullinated myelin basic protein induces experimental autoimmune encephalomyelitis in Lewis rats through a diverse T cell repertoire.
    Journal of neuroimmunology, 1998, Aug-01, Volume: 88, Issue:1-2

    Topics: Animals; Antibody Formation; Citrulline; Disease Susceptibility; Encephalomyelitis, Autoimmune, Experimental; Epitopes; Female; Guinea Pigs; Immunochemistry; Myelin Basic Protein; Peptide Fragments; Polymerase Chain Reaction; Rats; Rats, Inbred Lew; Receptors, Antigen, T-Cell, alpha-beta; T-Lymphocytes; Transcription, Genetic

1998
Rapid release and unusual stability of immunodominant peptide 45-89 from citrullinated myelin basic protein.
    Biochemistry, 1999, May-11, Volume: 38, Issue:19

    Topics: Brain; Cathepsin D; Citrulline; Humans; Immunodominant Epitopes; Marburg Virus Disease; Myelin Basic Protein; Time Factors

1999
Marburg's variant of multiple sclerosis correlates with a less compact structure of myelin basic protein.
    Molecular cell biology research communications : MCBRC, 1999, Volume: 1, Issue:1

    Topics: Acute Disease; Autoantigens; Citrulline; Humans; Image Processing, Computer-Assisted; Microscopy, Electron; Microscopy, Electron, Scanning Transmission; Multiple Sclerosis; Myelin Basic Protein; Protein Conformation; Protein Isoforms

1999
Highly deiminated isoform of myelin basic protein from multiple sclerosis brain causes fragmentation of lipid vesicles.
    Journal of neuroscience research, 1999, Aug-15, Volume: 57, Issue:4

    Topics: Animals; Arginine; Cattle; Citrulline; Electrochemistry; Humans; Imines; Light; Liposomes; Multiple Sclerosis; Myelin Basic Protein; Protein Isoforms; Scattering, Radiation

1999
Cryoelectron microscopy of protein-lipid complexes of human myelin basic protein charge isomers differing in degree of citrullination.
    Journal of structural biology, 2000, Volume: 129, Issue:1

    Topics: Adult; Arginine; Autoimmune Diseases; Citrulline; Cryoelectron Microscopy; G(M1) Ganglioside; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Macromolecular Substances; Microscopy, Electron, Scanning; Multiple Sclerosis; Myelin Basic Protein; Phosphatidylserines; Protein Isoforms; Protein Processing, Post-Translational

2000
Fyn tyrosine kinase participates in the compact myelin sheath formation in the central nervous system.
    Neuroscience research, 2000, Volume: 37, Issue:1

    Topics: Animals; Blotting, Western; Central Nervous System; Citrulline; Immunohistochemistry; Mice; Mice, Knockout; Myelin Basic Protein; Myelin Sheath; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2000
Deimination of myelin basic protein. 1. Effect of deimination of arginyl residues of myelin basic protein on its structure and susceptibility to digestion by cathepsin D.
    Biochemistry, 2000, May-09, Volume: 39, Issue:18

    Topics: Animals; Arginine; Cathepsins; Cattle; Chromatography, High Pressure Liquid; Citrulline; Demyelinating Autoimmune Diseases, CNS; Hydrolases; Kinetics; Mass Spectrometry; Models, Molecular; Myelin Basic Protein; Peptide Fragments; Protein Conformation; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases

2000
Deimination of myelin basic protein. 2. Effect of methylation of MBP on its deimination by peptidylarginine deiminase.
    Biochemistry, 2000, May-09, Volume: 39, Issue:18

    Topics: Animals; Arginine; Brain; Cathepsin D; Cattle; Citrulline; Humans; Hydrolases; Kinetics; Mass Spectrometry; Methylation; Multiple Sclerosis; Myelin Basic Protein; Peptide Fragments; Protein Processing, Post-Translational; Protein Structure, Secondary; Protein Structure, Tertiary; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases

2000
Enhanced T cell responsiveness to citrulline-containing myelin basic protein in multiple sclerosis patients.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2000, Volume: 6, Issue:4

    Topics: Adult; Cell Line; Citrulline; Humans; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Myelin Basic Protein; Peptide Fragments; Reference Values; T-Lymphocytes

2000
IgG reactivity against citrullinated myelin basic protein in multiple sclerosis.
    Journal of neuroimmunology, 2001, Jul-02, Volume: 117, Issue:1-2

    Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Citrulline; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; Male; Middle Aged; Molecular Sequence Data; Multiple Sclerosis; Myelin Basic Protein; Protein Processing, Post-Translational

2001
Peptidylarginine deiminase: a candidate factor in demyelinating disease.
    Journal of neurochemistry, 2002, Volume: 81, Issue:2

    Topics: Age of Onset; Animals; Brain; Brain Chemistry; Citrulline; Demyelinating Diseases; Disease Models, Animal; Disease Progression; Enzyme Activation; Gene Dosage; Hydrolases; Mice; Mice, Transgenic; Myelin Basic Protein; Myelin Sheath; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; RNA, Messenger; Solubility; Transgenes; Up-Regulation

2002
Immunohistochemical localization of citrullinated proteins in adult rat brain.
    The Journal of comparative neurology, 2003, May-05, Volume: 459, Issue:3

    Topics: Animals; Astrocytes; Brain Chemistry; Citrulline; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; Male; Myelin Basic Protein; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley

2003
Interaction of the 18.5-kD isoform of myelin basic protein with Ca2+ -calmodulin: effects of deimination assessed by intrinsic Trp fluorescence spectroscopy, dynamic light scattering, and circular dichroism.
    Protein science : a publication of the Protein Society, 2003, Volume: 12, Issue:7

    Topics: Acrylamides; Amino Acid Sequence; Animals; Calcium; Calmodulin; Cations, Divalent; Circular Dichroism; Citrulline; Humans; Molecular Sequence Data; Multiple Sclerosis; Myelin Basic Protein; Protein Isoforms; Scattering, Radiation; Spectrometry, Fluorescence

2003
Effect of arginine loss in myelin basic protein, as occurs in its deiminated charge isoform, on mediation of actin polymerization and actin binding to a lipid membrane in vitro.
    Biochemistry, 2005, Mar-08, Volume: 44, Issue:9

    Topics: Actin Cytoskeleton; Actins; Amino Acid Sequence; Animals; Arginine; Citrulline; Exons; Imines; Lipid Bilayers; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Myelin Basic Protein; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Isoforms; Recombinant Proteins; Static Electricity; Xenotropic and Polytropic Retrovirus Receptor

2005
Expression of citrullinated proteins in murine experimental autoimmune encephalomyelitis.
    The Journal of comparative neurology, 2005, Jun-06, Volume: 486, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Cerebral Cortex; Citrulline; Encephalomyelitis, Autoimmune, Experimental; Female; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Glycoproteins; Mice; Mice, Inbred C57BL; Myelin Basic Protein; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Spinal Cord; Time Factors

2005
PADI4 gene in multiple sclerosis: a family-based association study.
    Journal of neuroimmunology, 2006, Volume: 177, Issue:1-2

    Topics: Adult; Biomarkers; Central Nervous System; Chromosome Mapping; Citrulline; DNA Mutational Analysis; Female; France; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Haplotypes; Humans; Hydrolases; Male; Multiple Sclerosis; Myelin Basic Protein; Myelin Sheath; Polymorphism, Single Nucleotide; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; White People

2006
Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated.
    Journal of neuroscience research, 2007, Volume: 85, Issue:9

    Topics: 5-Methylcytosine; Blotting, Western; Brain; Citrulline; CpG Islands; DNA; DNA, Single-Stranded; Fluorescent Antibody Technique; Humans; Hydrolases; Methylation; Multiple Sclerosis; Myelin Basic Protein; Promoter Regions, Genetic; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Reverse Transcriptase Polymerase Chain Reaction; Sulfites; Thymus Gland

2007
Myelin localization of peptidylarginine deiminases 2 and 4: comparison of PAD2 and PAD4 activities.
    Laboratory investigation; a journal of technical methods and pathology, 2008, Volume: 88, Issue:4

    Topics: Animals; Arginine; Blotting, Western; Brain; Citrulline; Humans; Hydrolases; Immunohistochemistry; Mice; Mice, Knockout; Myelin Basic Protein; Myelin Sheath; Phosphatidylcholines; Phosphatidylserines; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases

2008
Accumulation of citrullinated proteins by up-regulated peptidylarginine deiminase 2 in brains of scrapie-infected mice: a possible role in pathogenesis.
    The American journal of pathology, 2008, Volume: 173, Issue:4

    Topics: Animals; Astrocytes; Brain; Citrulline; Electrophoresis, Gel, Two-Dimensional; Fluorescent Antibody Technique; Fructose-Bisphosphate Aldolase; Glial Fibrillary Acidic Protein; Hydrolases; Immunohistochemistry; Mice; Mice, Inbred C57BL; Myelin Basic Protein; Phosphopyruvate Hydratase; Protein Transport; Protein-Arginine Deiminases; Proteins; PrPSc Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Up-Regulation

2008
Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease.
    Journal of medicinal chemistry, 2008, Dec-25, Volume: 51, Issue:24

    Topics: Animals; Chemistry, Pharmaceutical; Citrulline; Drug Design; Epitopes; Humans; Leukocytes, Mononuclear; Ligands; Models, Chemical; Multiple Sclerosis; Myelin Basic Protein; Peptides; Peptides, Cyclic; Th1 Cells

2008
Targeted analysis of protein citrullination using chemical modification and tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2009, Volume: 23, Issue:17

    Topics: Animals; Cattle; Citrulline; Humans; Hydrolases; Myelin Basic Protein; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Serum Albumin; Tandem Mass Spectrometry

2009
A technique for the specific enrichment of citrulline-containing peptides.
    Analytical biochemistry, 2010, Volume: 403, Issue:1-2

    Topics: Amino Acid Sequence; Cell Line, Tumor; Chemistry Techniques, Analytical; Citrulline; Humans; Hydrolases; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Myelin Basic Protein; Peptides; Phenylglyoxal; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2010
Adhesive properties and inflammatory potential of citrullinated myelin basic protein peptide 45-89.
    Neurochemical research, 2012, Volume: 37, Issue:9

    Topics: Animals; Biotransformation; Blotting, Western; Cell Adhesion; Cell Death; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Citrulline; Inflammation; Lipids; Microglia; Myelin Basic Protein; NF-kappa B; Nitric Oxide; Oligodendroglia; Peptide Fragments; Rats; Rats, Wistar; Spectrum Analysis

2012
Presence and role of anti-citrullinated protein antibodies in experimental arthritis models.
    Arthritis and rheumatism, 2013, Volume: 65, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Autoantibodies; Autoantigens; Citrulline; Collagen Type II; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; False Positive Reactions; Fibrinogen; Freund's Adjuvant; Genetic Predisposition to Disease; Immunotherapy, Active; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Myelin Basic Protein; Protein Processing, Post-Translational; Proteins

2013
Identification and characterization of citrulline-modified brain proteins by combining HCD and CID fragmentation.
    Proteomics, 2013, Volume: 13, Issue:17

    Topics: Alzheimer Disease; Animals; Brain; Cattle; Chromatography, Liquid; Citrulline; Glial Fibrillary Acidic Protein; Humans; Hydrolases; Mass Spectrometry; Myelin Basic Protein; Nervous System Diseases; Neurogranin; Protein-Arginine Deiminases

2013
Specific biotinylation and sensitive enrichment of citrullinated peptides.
    Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:29

    Topics: Biotinylation; Citrulline; Humans; Myelin Basic Protein; Peptides; Protein Processing, Post-Translational; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2013
Anti-CCP antibody levels are not associated with MS: results from a case-control study.
    BioMed research international, 2015, Volume: 2015

    Topics: Adult; Antibodies, Anti-Idiotypic; Arthritis, Rheumatoid; Central Nervous System; Citrulline; Early Diagnosis; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Myelin Basic Protein; Peptides

2015
Plasma citrulline levels are increased in patients with multiple sclerosis.
    Journal of the neurological sciences, 2018, 04-15, Volume: 387

    Topics: Adult; Aged; Arginine; Citrulline; Disability Evaluation; Female; Glutamine; Humans; Immunologic Factors; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Myelin Basic Protein; Nitric Oxide; Statistics, Nonparametric

2018
Citrullinated myelin induces microglial TNFα and inhibits endogenous repair in the cuprizone model of demyelination.
    Journal of neuroinflammation, 2021, Dec-27, Volume: 18, Issue:1

    Topics: Animals; Cells, Cultured; Chelating Agents; Citrulline; Cuprizone; Cytokines; Demyelinating Diseases; Mice; Mice, Inbred C57BL; Microglia; Microinjections; Motor Cortex; Myelin Basic Protein; Myelin Sheath; Tumor Necrosis Factor-alpha

2021