citrulline has been researched along with methotrexate in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 11 (57.89) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Agnihotri, N; Deodhar, SD; Ganguly, NK; Wanchu, A | 1 |
| Bambery, P; Khullar, M; Sud, A; Wanchu, A | 1 |
| Beri, A; Gupta, A; Khullar, M; Singh, S | 1 |
| Alessandri, C; Bombardieri, M; Cinquini, M; Magrini, L; Papa, N; Tincani, A; Valesini, G | 1 |
| Tłustochowicz, W | 1 |
| Fijlstra, M; Kamps, WA; Rings, EH; Tissing, WJ; van Dijk, TH; Verkade, HJ | 1 |
| Borisova, OL; Shilkina, NP; Vinogradov, AA; Voronina, MS | 1 |
| af Klint, E; Catrina, AI; Engström, M; Makrygiannakis, D; Nicholas, AP; Pruijn, GJ; Revu, S | 1 |
| Fijlstra, M; Plösch, T; Rings, EH; Tissing, WJ; van Dijk, TH; Verkade, HJ | 1 |
| Ferdous, M; Fijlstra, M; Harmsen, HJ; Koning, AM; Rings, EH; Tissing, WJ | 1 |
| Draborg, AH; Houen, G; Jacobsen, S; Troelsen, L; Westergaard, MW | 1 |
| Alasti, F; Aletaha, D; Smolen, JS | 1 |
| Groen, AK; Havinga, R; Kuiken, NS; Rings, EH; Tissing, WJ | 1 |
| Catrina, AI; Defranoux, N; Hensvold, AH; Israelsson, L; Joshua, V; Larkin, M; Li, W; Lundberg, K; Padyukov, L; Qureshi, F; Saevarsdottir, S | 1 |
| Andersen, V; Bennike, TB; Birkelund, S; Bonderup, OK; Bøgsted, M; Carlsen, TG; Christiansen, G; Ellingsen, T; Glerup, H; Meyer, MK; Stensballe, A | 1 |
| Bartels, CM; Bier, AM; Donlon, TZ; Holmes, CL; Osman, F; Peyton, CG; Shelef, MA | 1 |
| da Silva Ferreira, AR; Harmsen, HJM; Havinga, R; Lichtenberg Cloo, S; Tissing, WJE; Vermeij, WP; Wardill, HR | 1 |
| Christensen, M; De Pietri, S; Frandsen, TL; Grell, K; Müller, K; Rathe, M | 1 |
| da Silva Ferreira, AR; Garssen, J; Harmsen, HJM; Harthoorn, LF; Hartog, A; Ten Klooster, JP; Tissing, WJE; van Bergenhenegouwen, J; van der Aa, SAJ; Wardill, HR; Wehkamp, T | 1 |
2 trial(s) available for citrulline and methotrexate
| Article | Year |
|---|---|
Decrease of anti-cyclic citrullinated peptide antibodies and rheumatoid factor following anti-TNFalpha therapy (infliximab) in rheumatoid arthritis is associated with clinical improvement.
Topics: Adult; Aged; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Autoantibodies; Biomarkers; Citrulline; Drug Therapy, Combination; Female; Humans; Infliximab; Male; Methotrexate; Middle Aged; Rheumatoid Factor; Severity of Illness Index; Treatment Outcome | 2004 |
Local administration of glucocorticoids decreases synovial citrullination in rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Citrulline; Dexamethasone; Double-Blind Method; Female; Glucocorticoids; Humans; Hydrolases; Immunohistochemistry; Injections, Intra-Articular; Male; Methotrexate; Middle Aged; Peptides; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Synovial Membrane; Time Factors; Tissue Culture Techniques; Treatment Outcome; Triamcinolone Acetonide | 2012 |
17 other study(ies) available for citrulline and methotrexate
| Article | Year |
|---|---|
Plasma reactive nitrogen intermediate levels in patients with clinically active rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Citrulline; Female; Free Radicals; Humans; Male; Methotrexate; Nitrites; Nitrogen | 1996 |
Nitric oxide production is increased in patients with inflammatory myositis.
Topics: Adolescent; Adult; Biomarkers; Citrulline; Dermatomyositis; Female; Humans; Inflammation; Male; Methotrexate; Middle Aged; Nitric Oxide; Nitrites; Polymyositis; Prednisolone; Reference Values | 1999 |
Comparison of serum nitric oxide levels in active juvenile rheumatoid arthritis with those of patients in remission.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alkylating; Arthritis, Juvenile; Biomarkers; Blood Sedimentation; Child; Chlorambucil; Citrulline; Female; Health Status; Humans; Male; Methotrexate; Naproxen; Nitric Oxide; Predictive Value of Tests; Reactive Nitrogen Species; Reference Values; Remission Induction; Steroids; Surveys and Questionnaires; Up-Regulation | 2004 |
[Modern strategy of diagnostics and management of patients with rheumatoid arthritis].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Autoantibodies; Biomarkers; Citrulline; Female; Humans; Male; Methotrexate; Prednisone; Pregnancy; Prognosis; Rheumatoid Factor | 2006 |
Lactose maldigestion during methotrexate-induced gastrointestinal mucositis in a rat model.
Topics: Absorption; Animals; Citrulline; Digestion; Gastrointestinal Diseases; Glucose; Glycoside Hydrolases; Immunohistochemistry; Injections, Intravenous; Intestinal Mucosa; Jejunum; Lactase; Lactose; Male; Methotrexate; Microvilli; Mucositis; Pilot Projects; Rats; RNA, Messenger | 2011 |
[Methotrexate-induced changes in the concentration of antibodies to mutaded citrullinated vimentin in blood serum of patients with rheumatoid arthritis].
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Autoantibodies; Biomarkers; Citrulline; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Mutation; Vimentin | 2011 |
Continuous enteral administration can overcome the limited capacity to absorb glucose in rats with methotrexate-induced gastrointestinal mucositis.
Topics: Animals; Antimetabolites, Antineoplastic; Citrulline; Enteral Nutrition; Glucose; Intestinal Absorption; Intestinal Mucosa; Male; Methotrexate; Mucositis; Rats; Rats, Wistar | 2013 |
Substantial decreases in the number and diversity of microbiota during chemotherapy-induced gastrointestinal mucositis in a rat model.
Topics: Animals; Citrulline; In Situ Hybridization, Fluorescence; Intestinal Mucosa; Male; Methotrexate; Microbiota; Mucositis; Random Allocation; Rats; Rats, Wistar | 2015 |
Isotypes of Epstein-Barr virus antibodies in rheumatoid arthritis: association with rheumatoid factors and citrulline-dependent antibodies.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Viral; Antigens, Viral; Arthritis, Rheumatoid; Citrulline; Epstein-Barr Virus Nuclear Antigens; Female; Herpesvirus 4, Human; Humans; Immunoglobulin Isotypes; Male; Methotrexate; Middle Aged; Rheumatoid Factor; Young Adult | 2015 |
Rheumatoid factor, not antibodies against citrullinated proteins, is associated with baseline disease activity in rheumatoid arthritis clinical trials.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Autoantibodies; Citrulline; Female; Humans; Male; Methotrexate; Middle Aged; Outcome Assessment, Health Care; Peptides, Cyclic; Randomized Controlled Trials as Topic; Rheumatoid Factor; Rituximab; Severity of Illness Index | 2015 |
Effect of minimal enteral feeding on recovery in a methotrexate-induced gastrointestinal mucositis rat model.
Topics: Animals; Antimetabolites, Antineoplastic; Citrulline; Disease Models, Animal; Enteral Nutrition; Humans; Intestinal Mucosa; Male; Methotrexate; Mucositis; Rats; Rats, Wistar | 2016 |
Serum RANKL levels associate with anti- citrullinated protein antibodies in early untreated rheumatoid arthritis and are modulated following methotrexate.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Autoantibodies; Citrulline; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Linear Models; Male; Methotrexate; Middle Aged; Phosphopyruvate Hydratase; RANK Ligand; Synovial Membrane; Time Factors; Vimentin | 2015 |
Proteome Analysis of Rheumatoid Arthritis Gut Mucosa.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Autoantibodies; Case-Control Studies; Citrulline; Colon; Epithelial Cells; Female; Gene Expression Regulation; Humans; Intestinal Mucosa; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Peptides, Cyclic; Proteome; Tetrahydrofolate Dehydrogenase | 2017 |
Reduced IgG titers against pertussis in rheumatoid arthritis: Evidence for a citrulline-biased immune response and medication effects.
Topics: Adolescent; Arthritis, Rheumatoid; Bordetella pertussis; Case-Control Studies; Citrulline; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Methotrexate; Pertussis Vaccine; Whooping Cough | 2019 |
Pre-therapy fasting slows epithelial turnover and modulates the microbiota but fails to mitigate methotrexate-induced gastrointestinal mucositis.
Topics: Animals; Bacteria; Cell Proliferation; Citrulline; Enterocytes; Fasting; Feces; Gastrointestinal Microbiome; Gastrointestinal Tract; Intestinal Mucosa; Jejunum; Lactobacillus; Male; Methotrexate; Mucositis; Rats; Rats, Wistar; Weight Loss | 2020 |
Citrulline as a biomarker of bacteraemia during induction treatment for childhood acute lymphoblastic leukaemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bacteria; Biomarkers; Child; Child, Preschool; Citrulline; Doxorubicin; Female; Follow-Up Studies; Humans; Induction Chemotherapy; Infant; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Prospective Studies; Retrospective Studies; Vincristine | 2021 |
Development of a self-limiting model of methotrexate-induced mucositis reinforces butyrate as a potential therapy.
Topics: Animals; Antimetabolites, Antineoplastic; Butyrates; Citrulline; Cytokines; Female; Ileum; Intestinal Mucosa; Leucovorin; Methotrexate; Mice, Inbred C57BL; Mucositis; Organoids; Tissue Culture Techniques | 2021 |