citrulline has been researched along with glutamic acid in 108 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (21.30) | 18.7374 |
| 1990's | 26 (24.07) | 18.2507 |
| 2000's | 31 (28.70) | 29.6817 |
| 2010's | 19 (17.59) | 24.3611 |
| 2020's | 9 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M | 1 |
| Costa, E; Kiedrowski, L; Wroblewski, JT | 1 |
| Blachier, F; Gomis, R; Malaisse, WJ; Mourtada, A; Sener, A | 1 |
| Brosnan, JT; Brosnan, ME; Dhanakoti, SN; Herzberg, GR | 1 |
| Hecker, M; Mitchell, JA; Sessa, WC; Vane, JR | 1 |
| Bredt, DS; Snyder, SH | 1 |
| Briand, P; Cathelineau, L; Kamoun, P; Petit, F; Rabier, D | 1 |
| Coleman, AE; Cooper, AJ; Filc-DeRicco, S; Gelbard, AS; Nieves, E | 1 |
| Chen, CH; Tabita, FR; Van Baalen, C | 1 |
| Buttrose, M; McKellar, D; Welbourne, TC | 1 |
| Hirasawa, T; Saheki, T; Yajima, Y | 1 |
| Gray, RG; Hill, SE; Pollitt, RJ | 1 |
| Henslee, JG; Jones, ME | 1 |
| Zollner, H | 1 |
| Ishikawa, Y; Kaiser-Kupfer, MI; Kuwabara, T | 1 |
| Anderson, PM; Casey, CA | 1 |
| Fahimi, FM; Kientsch-Engel, RI; Siess, EA; Wieland, OH | 1 |
| Küster, U; Letko, G; Ulrich, H | 1 |
| Crozier, GL; Freedland, RA; Hicks, BL; Meijer, AJ | 1 |
| Hida, W; Kikuchi, Y; Miki, H; Mizusawa, A; Ogawa, H; Shirato, K | 1 |
| Cini, M; Dostert, P; Marrari, P; Strolin Benedetti, M | 1 |
| De Loore, KL; Lesage, AS; Leysen, JE; Peeters, L | 1 |
| Gross, KL; Prior, RL | 1 |
| Blumsom, NL; Gardiner, KA; Laming, PR | 1 |
| Dejong, CH; Deutz, NE; Soeters, PB | 1 |
| Hartman, WJ; Prior, RL; Torre, PM | 1 |
| Bloom, SR; Bradford, HF; Foley, P; Ghatei, M; Hughes, PD; Khandanian, N; Wu, JY | 1 |
| Sorkin, LS | 1 |
| Gunasekaran, M; Gunasekaran, S; Imbayagwo, M; Manavathu, E; McDonald, L | 1 |
| Chen, FY; Ishine, T; Lai, CC; Lee, TJ; Sarwinski, S | 1 |
| Bardet, J; Cadoudal, M; Drouin, V; Kuchler, G; Meyer-Gast, D; Poggi-Travert, F; Rabier, D; Saudubray, JM | 1 |
| Czachurski, J; Seller, H; Zanzinger, J | 1 |
| Indiveri, C; Palmieri, F; Stipani, I; Tonazzi, A | 1 |
| Akatsu, T; Kawamoto, S; Kerlin, P; Kobayashi, K; Lynch, SV; Matsunami, H; Nakagawa, S; Saheki, T; Steadman, C; Strong, RW | 1 |
| Condés-Lara, M; Corkidi, G; Léon-Olea, M; Martínez-Lorenzana, G; Talavera, E | 1 |
| Quast, MJ; Wei, J | 1 |
| Deutz, NE; Pouw, EM; Schols, AM; Wouters, EF | 1 |
| Brennan, PA; de la Riva, C; Kendrick, KM; Keverne, EB; Schellinck, HM | 1 |
| Almeida, A; Bolaños, JP; Heales, SJ; Medina, JM; Vega-Agapito, V | 1 |
| Hughes, MG; McAdoo, DJ; Robak, G; Xu, GY | 1 |
| Alabadí, JA; Lasbennes, F; Pinard, E; Seylaz, J; Thibault, JL | 1 |
| Barrera-Mera, B; De La Riva, C; Guevara-Guzmán, R; Kendrick, KM | 1 |
| Lawand, NB; McNearney, T; Westlund, KN | 1 |
| Bergmans, PL; Kuiper, MA; Scheltens, P; Teerlink, T; Visser, JJ; Wolters, EC | 1 |
| Barziza, DE; Buentello, JA; Gatlin, DM | 1 |
| Abarca, C; Contreras, E; Oliva, P; Sepúlveda, MJ; Silva, E | 1 |
| Cagiano, R; Cassano, T; Cuomo, V; Kendrick, KM; Pietra, C; Steardo, L; Tattoli, M; Trabace, L | 1 |
| Horn, G; Kendrick, KM; McCabe, BJ | 1 |
| Ahlemeyer, B; Assmann, B; Exner-Camps, S; Hoffmann, GF; Hörster, F; Kohlmüller, D; Kölker, S; Krieglstein, J; Mayatepek, E; Okun, JG | 1 |
| Auguet, M; Bigg, D; Chabrier, PE; Dolo, C; Harnett, JJ; Viossat, I | 1 |
| Frak, E; Guillaumie, S; Le Roux, X; Millard, P; Wendler, R | 1 |
| Lefebvre, RA; Timmermans, JP; Van Geldre, LA | 1 |
| Chesneau, D; de la Riva, C; Fabre-Nys, C; Hinton, MR; Kendrick, KM; Locatelli, A; Ohkura, S | 1 |
| Bracht, A; Bracht, L; Ishii-Iwamoto, EL; Kelmer-Bracht, AM; Lousano, SH; Yassuda Filho, P | 1 |
| Arai, T; Blackshaw, S; Eliasson, MJ; Ferrante, RJ; Gupta, A; Krug, D; Sawa, A; Snyder, SH; Watkins, CC | 1 |
| COHEN, PP; GRISOLIA, S | 3 |
| BURRIS, RH; COHEN, PP; GRISOLIA, S | 1 |
| RAVEL, JM; REGER, JL; SHIVE, W | 1 |
| BISHOP, SH; CAMPBELL, JW | 1 |
| CRAFT, MK; DEWALD, HA; NICOLAIDES, ED | 1 |
| BERLINGUET, L; CHARBONNEAU, R | 1 |
| Crauwels, M; Donaton, MC; Holsbeeks, I; Lagatie, O; Thevelein, JM; Van Zeebroeck, G; Winderickx, J | 1 |
| FELDOTT, G; LARDY, HA | 1 |
| Burkhardt, B; Ludwig, RA; Taira, M; Valtersson, U | 1 |
| Büyükuysal, RL | 1 |
| Arnaud-Battandier, F; Cynober, L; Loï, C; Nakib, S; Neveux, N | 1 |
| Boelens, PG; Cynober, L; De Bandt, JP; Melis, GC; Popovici, T; van der Sijp, JR; van Leeuwen, PA | 1 |
| Akashi, K; Takahara, K; Yokota, A | 1 |
| Baldwin, RL; Bequette, BJ; Oba, M; Owens, SL | 1 |
| Karlsson, T; Nordgren, A; Wiklund, L | 1 |
| Bramhall, SR; Buckels, JA; Mayer, D; Mirza, DF; Murphy, N; Richards, DA; Silva, MA; Wigmore, SJ | 1 |
| Alcaraz-Zubeldia, M; Diaz-Ruiz, A; Maldonado, V; Montes, S; Ríos, C; Salgado-Ceballos, H; Tristan, L | 1 |
| Bishoff, L; Cynober, L; Garbay, C; Hamani, D; Loï, C; Moinard, C; Neveux, N | 1 |
| Bailey, I; Clarke, GD; Godfrey, L; Hourani, SM; Kitchen, I; Toms, NJ | 1 |
| Au, WL; Lim, CC; Wong, YC; Xu, M; Ye, J | 1 |
| Deutz, NE | 1 |
| Castillo, L; Roth, RM; Tharakan, JF; Young, VR; Yu, YM; Zurakowski, D | 1 |
| Jing, Y; Liu, P; Zhang, H | 1 |
| Baumgartner, WA; Blue, ME; Brock, MV; Johnston, MV; Lange, MS; Lowenstein, CJ; Troncoso, JC; Tseng, EE | 1 |
| Brown, M; Duckworth, L; Froyen, M; Gauger, C; Kissoon, N; Murphy, S; Sandler, E; Sullivan, KJ | 1 |
| Ball, RO; Pencharz, P; Rafii, M; Sgro, M; Tomlinson, C | 1 |
| Davids, M; de Mol, BA; Paulus, WJ; Richir, MC; van Leeuwen, PA; Vermeulen, MA; Visser, M; Wisselink, W | 1 |
| Ball, RO; Pencharz, P; Rafii, M; Tomlinson, C | 1 |
| Bekri, S; Brasse-Lagnel, C; Desfeux, A; El Ghazi, F; Gonzalez, BJ; Jégou, S; Laudenbach, V; Lesueur, C; Marret, S; Mazur, D; Prevot, V; Remy-Jouet, I; Richard, V; Roux, C | 1 |
| Blachier, F; Bos, C; Boutry, C; Cynober, L; Matsumoto, H; Moinard, C; Tomé, D; Yin, Y | 1 |
| Boix, J; Cabrera-Pastor, A; Felipo, V; Llansola, M; Reznikov, V | 1 |
| Agustí, A; Cauli, O; Felipo, V; González-Usano, A | 1 |
| Gören, MZ; Kaleli, M; Oktay, S; Özyurt Bayraktar, H; Terzioğlu, B; Yananlı, H | 1 |
| Guo, K; Hao, N; Hu, N; Li, Y; Mu, J; Xu, L; Xu, S; Yan, M | 1 |
| Bilkey, DK; Collie, ND; Dean, B; Jing, Y; Liu, P; Zhang, H | 1 |
| Bottrel, N; Corum, DG; Drevets, WC; Fiehn, O; Kaddurah-Daouk, R; Motsinger-Reif, A; Rotroff, DM; Salvadore, G; Singh, J | 1 |
| Collie, ND; Gupta, N; Jing, Y; Liu, P; Smith, PF; Zhang, H | 1 |
| Kang, YS; Lee, KE | 1 |
| An, Z; Anami, Y; Gui, X; Tsuchikama, K; Xiong, W; Yamazaki, CM; Zhang, N | 1 |
| Arenas, YM; Cabrera-Pastor, A; Felipo, V; Montoliu, C; Taoro-Gonzalez, L | 1 |
| Dotsikas, Y; Loukas, YL; Manta-Vogli, PD; Schulpis, KH | 1 |
| Bazer, FW; Gilbreath, KR; Nawaratna, GI; Satterfield, MC; Wickersham, TA; Wu, G | 2 |
| Bazer, FW; Cleere, JJ; Gilbreath, KR; Satterfield, MC; Wu, G | 1 |
| Gudbrandsen, OA; Rønnevik, AK | 1 |
| Alvarenga, AC; Appel, RM; Arima, EC; Ayache, R; Budib, MA; D'Amora, P; Diaz, RS; Evans, SS; Júnior, SS; Martins, WG; Nagourney, RA; Palma, AM; Pontes, HBD; Salzgeber, MB; Silva, FC; Silva, IDCG; Silva, NLF; Silva, RMS | 1 |
| Anand, SS; Atkinson, SA; Azab, S; Britz-McKibbin, P; de Souza, RJ; Desai, D; Gupta, M; Morrison, K; Shanmuganathan, M; Sikorski, C; Teo, K | 1 |
| Akiduki, S; Matsumoto, H; Miura, N; Morishita, K; Yasuda, T | 1 |
| Ban, Q; Hou, YY; Huang, T; Ma, B; Shi, L; Zhang, ML; Zhang, Q; Zhou, YF | 1 |
| Burlina, AB; Cazzorla, C; Commone, A; Gragnaniello, V; Gueraldi, D; Häberle, J; Loro, C; Puma, A | 1 |
| Li, Y; Liu, XF; Lu, JJ; Qiang, JW; Yang, XY | 1 |
2 review(s) available for citrulline and glutamic acid
| Article | Year |
|---|---|
The role of asymmetric dimethylarginine and arginine in the failing heart and its vasculature.
Topics: Amidohydrolases; Arginine; Citrulline; Coronary Vessels; Glutamic Acid; Heart Failure; Humans; Nitric Oxide; Reactive Oxygen Species | 2010 |
Chronic hyperammonemia alters extracellular glutamate, glutamine and GABA and membrane expression of their transporters in rat cerebellum. Modulation by extracellular cGMP.
Topics: Animals; Cell Membrane; Cerebellum; Citrulline; Cyclic GMP; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hyperammonemia; Male; Neurotransmitter Transport Proteins; Rats; Rats, Wistar; Synaptic Transmission | 2019 |
5 trial(s) available for citrulline and glutamic acid
| Article | Year |
|---|---|
Adaptation to a long term (4 weeks) arginine- and precursor (glutamate, proline and aspartate)-free diet.
Topics: Adult; Analysis of Variance; Arginine; Aspartic Acid; Carbon Isotopes; Citrulline; Diet; Dietary Proteins; Female; Glutamic Acid; Homeostasis; Humans; Infusions, Intravenous; Isotope Labeling; Kinetics; Leucine; Male; Nitrogen Isotopes; Oxidation-Reduction; Proline; Time Factors; Urea | 2008 |
Effect of oral arginine supplementation on exhaled nitric oxide concentration in sickle cell anemia and acute chest syndrome.
Topics: Acute Chest Syndrome; Acute Disease; Administration, Oral; Adolescent; Anemia, Sickle Cell; Arginine; Aspartic Acid; Breath Tests; Child; Citrulline; Female; Glutamic Acid; Humans; Male; Nitrates; Nitric Oxide; Nitrites; Ornithine; Young Adult | 2010 |
Arginine synthesis from enteral glutamine in healthy adults in the fed state.
Topics: Arginine; Carbon Isotopes; Citrulline; Eating; Glutamic Acid; Glutamine; Humans; Ketoglutaric Acids; Male; Models, Biological; Nitrogen Isotopes; Ornithine; Young Adult | 2011 |
Quantitation of the arginine family amino acids in the blood of full-term infants perinatally in relation to their birth weight.
Topics: Arginine; Biomarkers; Birth Weight; Citrulline; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Infant, Newborn; Male; Ornithine; Prognosis; Proline | 2019 |
Ruminal microbes of adult sheep do not degrade extracellular l-citrulline.
Topics: Ammonia; Animal Feed; Animals; Arginine; Bacteria; Citrulline; Diet; Dietary Supplements; Female; Glutamic Acid; Glutamine; Ornithine; Proline; Rumen; Sheep; Urea | 2020 |
101 other study(ies) available for citrulline and glutamic acid
| Article | Year |
|---|---|
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2009 |
Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Granulocytes; Kainic Acid; N-Methylaspartate; Nitric Oxide Synthase; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
Metabolic and secretory response of parotid cells to cationic amino acids. Uptake and catabolism of L-arginine and L-ornithine.
Topics: Amylases; Animals; Arginine; Citrulline; Female; Glutamates; Glutamic Acid; Ketoglutaric Acids; NADP; Ornithine; Oxidation-Reduction; Parotid Gland; Rats; Transglutaminases; Urea | 1991 |
Renal arginine synthesis: studies in vitro and in vivo.
Topics: Alanine; Ammonium Chloride; Animals; Arginine; Aspartic Acid; Citrulline; Glomerular Filtration Rate; Glutamates; Glutamic Acid; Glutamine; Glycine; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Kinetics; Male; Rats; Rats, Inbred Strains; Serine | 1990 |
The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: L-glutamine inhibits the generation of L-arginine by cultured endothelial cells.
Topics: Animals; Aorta; Arginine; Argininosuccinic Acid; Cattle; Cell Line; Cells, Cultured; Citrulline; Endothelium, Vascular; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Mice; Muscle, Smooth, Vascular; Nitric Oxide; Rabbits | 1990 |
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.
Topics: Animals; Arginine; Aspartic Acid; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quisqualic Acid; Rats | 1989 |
Effects of organic acids on the synthesis of citrulline by intact rat liver mitochondria.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Adenosine Triphosphate; Animals; Butyrates; Citrulline; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Glutamates; Glutamic Acid; Kinetics; Male; Mitochondria, Liver; Propionates; Rats; Rats, Inbred Strains; Succinates; Succinic Acid; Valproic Acid | 1986 |
Short-term metabolic fate of [13N]ammonia in rat liver in vivo.
Topics: Alanine Transaminase; Amino Acids; Ammonia; Animals; Aspartate Aminotransferases; Carbamyl Phosphate; Chromatography, High Pressure Liquid; Citrulline; Cytoplasm; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Hepatic Veins; Kinetics; Liver; Male; Mitochondria, Liver; Portal Vein; Rats; Rats, Inbred Strains; Urea | 1987 |
DL-7-azatryptophan and citrulline metabolism in the cyanobacterium Anabaena sp. strain 1F.
Topics: Amino Acids; Bicarbonates; Carbon Radioisotopes; Citrulline; Cyanobacteria; Glutamates; Glutamic Acid; Glutamine; Kinetics; Tryptophan | 1987 |
Gut-liver interaction in glutamine homeostasis: portal ammonia role in uptake and metabolism.
Topics: Acid-Base Equilibrium; Alanine; Ammonia; Animals; Carbonates; Citrulline; Digestive System Physiological Phenomena; Glutamates; Glutamic Acid; Glutamine; Homeostasis; Liver; Male; Mitochondria, Liver; Portal Vein; Rats; Rats, Inbred Strains | 1987 |
Treatment of adult-type citrullinemia with administration of citrate.
Topics: Amino Acids; Ammonia; Circadian Rhythm; Citrates; Citric Acid; Citrulline; Glutamates; Glutamic Acid; Humans; Lactulose; Male; Middle Aged; Urea | 1981 |
Reduced ornithine catabolism in cultured fibroblasts and phytohaemagglutinin-stimulated lymphocytes from a patient with hyperornithinaemia, hyperammonaemia and homocitrullinuria.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Aspartate Ammonia-Lyase; Cells, Cultured; Citrulline; Fibroblasts; Glutamates; Glutamic Acid; Humans; Lymphocyte Activation; Lymphocytes; Ornithine; Phytohemagglutinins; Proline | 1982 |
Ornithine synthesis from glutamate in rat small intestinal mucosa.
Topics: Animals; Cell Fractionation; Citrulline; Glutamates; Glutamic Acid; Intestinal Mucosa; Intestine, Small; Kinetics; Male; Microscopy, Electron; Mitochondria; Ornithine; Ornithine-Oxo-Acid Transaminase; Rats; Rats, Inbred Strains; Transaminases | 1982 |
Regulation of the n-acetylglutamate content of rat hepatocytes by the glutamate concentration.
Topics: Ammonia; Animals; Aspartic Acid; Citrulline; Diet; Glutamates; Glutamic Acid; Liver; Ornithine; Rats; Urea | 1982 |
Toxic effects of ornithine and its related compounds on the retina.
Topics: Animals; Arginine; Citrulline; Glutamates; Glutamic Acid; Lysine; Ornithine; Pigment Epithelium of Eye; Proline; Putrescine; Rats; Rats, Inbred Strains; Retina | 1982 |
Glutamine-dependent synthesis of citrulline by isolated hepatic mitochondria from Squalus acanthias.
Topics: Ammonia; Ammonium Chloride; Animals; Citrulline; Dogfish; Glutamates; Glutamic Acid; Glutamine; Isoxazoles; Methionine Sulfoximine; Mitochondria, Liver | 1984 |
Possible role of Pi supply in mitochondrial actions of glucagon.
Topics: Animals; Cell Compartmentation; Citrulline; Glucagon; Glutamates; Glutamic Acid; Hormones; In Vitro Techniques; Liver; Male; Mitochondria, Liver; Phosphates; Rats; Rats, Inbred Strains; Urea | 1984 |
Citrulline synthesis--a tool for investigation of the mitochondrial energy metabolism.
Topics: Animals; Citrulline; Dietary Proteins; Energy Metabolism; Glutamates; Glutamic Acid; Kinetics; Mitochondria, Liver; Oxygen Consumption; Rats; Succinates; Succinic Acid; Temperature; Thermodynamics | 1984 |
Arginine uptake by isolated rat liver mitochondria.
Topics: Animals; Arginine; Citrulline; Glutamates; Glutamic Acid; Glutamine; Lysine; Male; Mitochondria, Heart; Mitochondria, Liver; Ornithine; Rats; Rats, Inbred Strains | 1984 |
Nitric oxide as a retrograde messenger in the nucleus tractus solitarii of rats during hypoxia.
Topics: Animals; Arginine; Citrulline; Dizocilpine Maleate; Drug Combinations; Enzyme Inhibitors; Glutamic Acid; Hypercapnia; Hypoxia; Male; Microinjections; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Respiration; Solitary Nucleus | 1995 |
Effect of ageing on tissue levels of amino acids involved in the nitric oxide pathway in rat brain.
Topics: Aging; Amino Acid Oxidoreductases; Amino Acids; Animals; Arginine; Aspartic Acid; Brain Chemistry; Citrulline; Glutamates; Glutamic Acid; Male; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Wistar | 1993 |
Neuroprotective sigma ligands interfere with the glutamate-activated NOS pathway in hippocampal cell culture.
Topics: Animals; Cells, Cultured; Citrulline; Cyclic GMP; Glutamic Acid; Hippocampus; Ligands; Neuroprotective Agents; Nitric Oxide Synthase; Radioligand Assay; Rats | 1995 |
Dietary arginine deficiency and gut ammonium infusion alter flux of urea cycle intermediates across the portal-drained viscera of pigs.
Topics: Alanine; Animals; Arginine; Citrulline; Diet; Digestive System; Glutamic Acid; Glutamine; Lysine; Ornithine; Portal Vein; Quaternary Ammonium Compounds; Regional Blood Flow; Swine; Urea; Viscera | 1995 |
Brain amino acid levels are related to seizure propensity in the gerbil (Meriones unguiculatus).
Topics: Amino Acids; Analysis of Variance; Animals; Arginine; Aspartic Acid; Behavior, Animal; Brain; Citrulline; Cysteine; Disease Susceptibility; Female; Gerbillinae; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycine; Male; Seizures | 1993 |
Intestinal glutamine and ammonia metabolism during chronic hyperammonaemia induced by liver insufficiency.
Topics: Alanine; Ammonia; Animals; Bile Ducts; Blood Flow Velocity; Body Weight; Chronic Disease; Citrulline; Diet; Glutamates; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Jejunum; Ligation; Male; Neurotransmitter Agents; Portacaval Shunt, Surgical; Portal System; Rats; Rats, Wistar | 1993 |
Dietary citrulline but not ornithine counteracts dietary arginine deficiency in rats by increasing splanchnic release of citrulline.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Blood Flow Velocity; Body Weight; Citrulline; Creatinine; Diet; Food; Glutamic Acid; Glutamine; Male; Ornithine; Orotic Acid; Proline; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Urea | 1994 |
The differential release of amino acids and neuropeptides from purified subpopulations of mammalian GABAergic and cholinergic cerebrocortical synaptosomes.
Topics: Acetylcholine; Amino Acids; Animals; Calcium; Cell Fractionation; Cerebral Cortex; Cholecystokinin; Citrulline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Neuropeptides; Rats; Rats, Sprague-Dawley; Somatostatin; Synaptosomes; Vasoactive Intestinal Peptide; Veratridine | 1993 |
NMDA evokes an L-NAME sensitive spinal release of glutamate and citrulline.
Topics: Animals; Arginine; Citrulline; Dialysis; Dizocilpine Maleate; Glutamates; Glutamic Acid; Injections, Spinal; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Spinal Cord | 1993 |
Influence of carbon and nitrogen sources on glutathione catabolic enzymes in Candida albicans during dimorphism.
Topics: Ammonia; Candida albicans; Citrulline; gamma-Glutamyltransferase; Glucose; Glutamic Acid; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Sucrose | 1995 |
Inhibition of cerebral neurogenic vasodilation by L-glutamine and nitric oxide synthase inhibitors and its reversal by L-citrulline.
Topics: Animals; Arginine; Cerebral Arteries; Citrulline; Enzyme Inhibitors; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Swine; Vasodilation | 1996 |
Therapeutic use of carbamylglutamate in the case of carbamoyl-phosphate synthetase deficiency.
Topics: Ammonia; Arginine; Carbamoyl-Phosphate Synthase (Ammonia); Child, Preschool; Citrulline; Glutamates; Glutamic Acid; Glutamine; Humans; Male | 1996 |
Neuronal nitric oxide reduces sympathetic excitability by modulation of central glutamate effects in pigs.
Topics: Animals; Arginine; Brain Stem; Citrulline; Enzyme Inhibitors; Glutamic Acid; Heart Rate; Hemodynamics; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Swine; Sympathetic Nervous System; Thiourea; Vagotomy | 1997 |
The purified and reconstituted ornithine/citrulline carrier from rat liver mitochondria: electrical nature and coupling of the exchange reaction with H+ translocation.
Topics: Amino Acid Transport Systems, Acidic; Animals; Antiporters; Aspartic Acid; Carrier Proteins; Cations, Monovalent; Citrulline; Glutamic Acid; Hydrogen-Ion Concentration; Intracellular Membranes; Kinetics; Membrane Potentials; Mitochondria, Liver; Mitochondrial ADP, ATP Translocases; Nigericin; Ornithine; Rats | 1997 |
Orthotopic liver transplantation for adult-onset type II citrullinaemia.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Ammonia; Arginine; Argininosuccinate Synthase; Brain Edema; Cause of Death; Citrulline; Diet, Protein-Restricted; Disease Progression; Fatal Outcome; Glutamic Acid; Hepatic Encephalopathy; Humans; Immunohistochemistry; Liver; Liver Transplantation; Male; Prognosis; Referral and Consultation | 1997 |
NADPH-diaphorase-stained neurons after experimental epilepsy in rats.
Topics: Animals; Arginine; Behavior, Animal; Brain; Citrulline; Electric Stimulation; Electrophysiology; Epilepsy, Generalized; Glutamic Acid; Histocytochemistry; Image Processing, Computer-Assisted; Kindling, Neurologic; Male; NADPH Dehydrogenase; Neurons; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar | 1997 |
Effect of nitric oxide synthase inhibitor on a hyperglycemic rat model of reversible focal ischemia: detection of excitatory amino acids release and hydroxyl radical formation.
Topics: Animals; Cell Survival; Citrulline; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glutamic Acid; Hydroxyl Radical; Hyperglycemia; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1998 |
Plasma and muscle amino acid levels in relation to resting energy expenditure and inflammation in stable chronic obstructive pulmonary disease.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Adipose Tissue; Aged; Alanine; Amino Acids; Arginine; Carrier Proteins; Case-Control Studies; Citrulline; Energy Metabolism; Glutamic Acid; Glutamine; Humans; Lipopolysaccharides; Lung Diseases, Obstructive; Membrane Glycoproteins; Middle Aged; Muscle, Skeletal; Muscular Diseases; Ornithine; Proteins; Rest | 1998 |
Changes in neurotransmitter release in the main olfactory bulb following an olfactory conditioning procedure in mice.
Topics: Animals; Aspartic Acid; Behavior, Animal; Carbohydrates; Citrulline; Conditioning, Psychological; Discrimination Learning; Female; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Mice, Inbred BALB C; Microdialysis; Neurotransmitter Agents; Norepinephrine; Olfactory Bulb; Olfactory Receptor Neurons; Smell; Taurine | 1998 |
Peroxynitrite anion stimulates arginine release from cultured rat astrocytes.
Topics: Animals; Animals, Newborn; Arginine; Astrocytes; Cells, Cultured; Citrulline; Glutamic Acid; Hydrogen Peroxide; Kinetics; Lysine; Nitrates; Nitric Oxide Donors; Oxidants; Rats; Rats, Wistar; Serine | 1999 |
Changes in amino acid concentrations over time and space around an impact injury and their diffusion through the rat spinal cord.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Citrulline; Glutamic Acid; Glycine; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine; Time Factors | 1999 |
7-Nitroindazole, a selective inhibitor of nNOS, increases hippocampal extracellular glutamate concentration in status epilepticus induced by kainic acid in rats.
Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Citrulline; Electroencephalography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Extracellular Space; Glutamic Acid; Hippocampus; Indazoles; Kainic Acid; Male; Microdialysis; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Status Epilepticus; Synaptic Transmission | 1999 |
Release of classical transmitters and nitric oxide in the rat olfactory bulb, evoked by vaginocervical stimulation and potassium, varies with the oestrus cycle.
Topics: Animals; Aspartic Acid; Cervix Uteri; Citrulline; Dopamine; Estrus; Female; gamma-Aminobutyric Acid; Glutamic Acid; Homovanillic Acid; Hydroxyindoleacetic Acid; Microdialysis; Neurotransmitter Agents; Nitric Oxide; Norepinephrine; Olfactory Bulb; Ovariectomy; Peripheral Nerves; Physical Stimulation; Potassium Chloride; Rats; Rats, Wistar; Vagina; Vagotomy; Vagus Nerve; Wakefulness | 2000 |
Amino acid release into the knee joint: key role in nociception and inflammation.
Topics: Amino Acids; Anesthetics, Local; Animals; Arginine; Arthritis; Carrageenan; Chromatography, High Pressure Liquid; Citrulline; Glutamic Acid; Hindlimb; Injections, Intra-Articular; Joints; Kaolin; Lidocaine; Male; Pain; Rats; Rats, Sprague-Dawley; Synovial Fluid | 2000 |
L-glutamate, L-arginine and L-citrulline levels in cerebrospinal fluid of Parkinson's disease, multiple system atrophy, and Alzheimer's disease patients.
Topics: Aged; Alzheimer Disease; Arginine; Citrulline; Glutamic Acid; Humans; Middle Aged; Multiple System Atrophy; Neurons; Nitric Oxide; Nitric Oxide Synthase; Parkinson Disease | 2000 |
Dietary arginine requirement of juvenile red drum (Sciaenops ocellatus) based on weight gain and feed efficiency.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Aquaculture; Arginine; Aspartic Acid; Citrulline; Energy Intake; Fishes; Glutamic Acid; Glycine; Nutritional Requirements; Ornithine; Weight Gain | 2000 |
Neurochemical changes after morphine, dizocilpine or riluzole in the ventral posterolateral thalamic nuclei of rats with hyperalgesia.
Topics: Analysis of Variance; Animals; Arginine; Aspartic Acid; Carrageenan; Citrulline; Dialysis Solutions; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamic Acid; Hindlimb; Hyperalgesia; Male; Microdialysis; Morphine; Neuroprotective Agents; Rats; Rats, Wistar; Riluzole; Thalamic Nuclei | 2000 |
Effects of ENA713 and CHF2819, two anti-Alzheimer's disease drugs, on rat amino acid levels.
Topics: Alzheimer Disease; Animals; Arginine; Aspartic Acid; Carbamates; Cholinesterase Inhibitors; Citrulline; Cyclic N-Oxides; Dose-Response Relationship, Drug; Excitatory Amino Acids; Extracellular Space; Glutamic Acid; Hippocampus; Male; Microdialysis; Neurons; Phenylcarbamates; Rats; Rats, Wistar; Rivastigmine; Synaptic Transmission; Taurine | 2001 |
GABA, taurine and learning: release of amino acids from slices of chick brain following filial imprinting.
Topics: Animals; Animals, Newborn; Arginine; Aspartic Acid; Behavior, Animal; Calcium; Cell Membrane; Chickens; Chromatography, High Pressure Liquid; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Imprinting, Psychological; Membrane Potentials; Neurons; Neuropsychological Tests; Potassium Chloride; Taurine; Telencephalon | 2001 |
3-Ureidopropionate contributes to the neuropathology of 3-ureidopropionase deficiency and severe propionic aciduria: a hypothesis.
Topics: Animals; beta-Alanine; Brain Diseases, Metabolic; Calcium; Cell Death; Cells, Cultured; Central Nervous System; Chick Embryo; Citrulline; Electron Transport; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formamides; Glutamic Acid; Mitochondria; Neurons; Neurotoxins; Oxidative Stress; Propionates; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Urea | 2001 |
Novel lipoic acid analogues that inhibit nitric oxide synthase.
Topics: Animals; Antioxidants; Arginine; Cell Death; Cell Line; Cell Survival; Citrulline; Drug Design; Enzyme Inhibitors; Glutamic Acid; Glutathione; Mice; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Thioctic Acid | 2002 |
Coupling sap flow velocity and amino acid concentrations as an alternative method to (15)N labeling for quantifying nitrogen remobilization by walnut trees.
Topics: Amino Acids; Arginine; Aspartic Acid; Biological Transport; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Juglans; Light; Nitrogen; Nitrogen Isotopes; Plant Shoots; Rheology; Seasons; Time Factors | 2002 |
L-citrulline recycling by argininosuccinate synthetase and lyase in rat gastric fundus.
Topics: Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Argininosuccinic Acid; Aspartic Acid; Citrulline; Dinoprost; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; Glutamic Acid; Glutamine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Thiolester Hydrolases; Ubiquitin Thiolesterase | 2002 |
Biphasic role of dopamine on female sexual behaviour via D2 receptors in the mediobasal hypothalamus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Citrulline; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Estradiol; Extracellular Space; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Goats; Hypothalamus, Middle; Luteinizing Hormone; Microdialysis; Norepinephrine; Ovariectomy; Pimozide; Prolactin; Quinpirole; Receptors, Dopamine D2; Serotonin; Sexual Behavior, Animal; Spiperone; Taurine; Time Factors | 2003 |
The urea cycle in the liver of arthritic rats.
Topics: Ammonia; Animals; Arthritis, Experimental; Aspartic Acid; Citrulline; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Kidney; Lactic Acid; Liver; Male; Models, Biological; Oxygen; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Time Factors; Urea | 2003 |
Species, strain and developmental variations in hippocampal neuronal and endothelial nitric oxide synthase clarify discrepancies in nitric oxide-dependent synaptic plasticity.
Topics: Animals; Citrulline; Endothelium, Vascular; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Immunohistochemistry; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Species Specificity; Synaptic Transmission | 2003 |
The catalytic rôle of carbamyl glutamate in citrulline biosynthesis.
Topics: Citrulline; Glutamates; Glutamic Acid | 1952 |
Catalytic rôle of of glutamate derivatives in citrulline biosynthesis.
Topics: Amino Acids; Catalysis; Citrulline; Glutamates; Glutamic Acid | 1953 |
Fate of deutero-labeled carbamyl glutamate in citrulline biosynthesis.
Topics: Amino Acids; Citrulline; Glutamates; Glutamic Acid | 1954 |
Aspartic acid inhibition of glutamic acid utilization for proline, citrulline and glutamine biosynthesis.
Topics: Amino Acids; Aspartic Acid; Biochemical Phenomena; Citrulline; Glutamates; Glutamic Acid; Glutamine; Lactobacillus; Proline | 1955 |
CARBAMYL PHOSPHATE SYNTHESIS IN THE EARTHWORM LUMBRICUS TERRESTRIS.
Topics: Adenosine Triphosphate; Animals; Bicarbonates; Carbamates; Carbamyl Phosphate; Citrulline; Glutamates; Glutamic Acid; Helminths; Intestines; Ligases; Metabolism; Oligochaeta; Ornithine; Research | 1963 |
THE SYNTHESIS OF 1-LYSINE, 1-ORNITHINE, 1-CITRULLINE, 1-GLUTAMIC ACID, AND 1-DESARGININE BRADYKININ.
Topics: Blood Pressure; Bradykinin; Bronchi; Chemistry, Pharmaceutical; Citrulline; Glutamates; Glutamic Acid; Guinea Pigs; Lysine; Ornithine; Peptides; Pharmacology; Research | 1963 |
A STUDY ON THE "IN VITRO" SYNTHESIS OF CITRULLINE. II. EFFECT OF GLUTAMIC ACID AND DERIVATIVES IN THE PRESENCE OF FUMARIC ACID.
Topics: Acetates; Amino Acids; Antimetabolites; Aspartic Acid; Carbamates; Carbon Dioxide; Citric Acid Cycle; Citrulline; Fumarates; Glutamates; Glutamic Acid; In Vitro Techniques; Liver; Pharmacology; Rats; Research | 1964 |
The Gap1 general amino acid permease acts as an amino acid sensor for activation of protein kinase A targets in the yeast Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Argininosuccinate Synthase; Base Sequence; Biological Transport; Catalytic Domain; Citrulline; Culture Media; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Gene Expression Regulation, Fungal; Glutamic Acid; Molecular Sequence Data; Mutation; Nitrogen; Protein Kinases; ras GTPase-Activating Proteins; Ribosomal Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2003 |
Metabolic functions of biotin. IV. The rôle of carbamyl-l-glutamic acid in the synthesis of citrulline by normal and biotin-deficient rats.
Topics: Animals; Biotin; Citrulline; Glutamates; Glutamic Acid; Rats | 1951 |
Arabidopsis thaliana GLN2-encoded glutamine synthetase is dual targeted to leaf mitochondria and chloroplasts.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Chloroplasts; Citrulline; Glutamate-Ammonia Ligase; Glutamic Acid; Mitochondria; Molecular Sequence Data; Ornithine; Oxidation-Reduction; Plant Leaves; Plants, Genetically Modified; Quaternary Ammonium Compounds; Recombinant Fusion Proteins; Sequence Alignment | 2004 |
Ischemia and reoxygenation induced amino acid release release and tissue damage in the slices of rat corpus striatum.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Calcium; Citrulline; Corpus Striatum; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hypoxia; Ions; Ischemia; L-Lactate Dehydrogenase; Male; Oxygen; Rats; Rats, Wistar; Reperfusion Injury; Taurine; Tetrodotoxin; Time Factors | 2004 |
Ornithine alpha-ketoglutarate metabolism in the healthy rat in the postabsorptive state.
Topics: Amino Acids, Branched-Chain; Animals; Arginine; Citrulline; Glutamic Acid; Intestinal Absorption; Intestinal Mucosa; Keto Acids; Ketoglutaric Acids; Liver; Male; Muscle, Skeletal; Ornithine; Proline; Rats; Rats, Wistar | 2005 |
The feeding route (enteral or parenteral) affects the plasma response of the dipetide Ala-Gln and the amino acids glutamine, citrulline and arginine, with the administration of Ala-Gln in preoperative patients.
Topics: Adult; Aged; Amino Acids; Analysis of Variance; Arginine; Citrulline; Dietary Supplements; Dipeptides; Enteral Nutrition; Female; Glutamic Acid; Glutamine; Humans; Male; Middle Aged; Parenteral Nutrition; Preoperative Care | 2005 |
Purification and characterization of glutamate N-acetyltransferase involved in citrulline accumulation in wild watermelon.
Topics: Acetyltransferases; Amidohydrolases; Amino Acid Sequence; Catalysis; Chloroplasts; Citrulline; Citrullus; Cloning, Molecular; Dehydration; DNA, Complementary; Glutamic Acid; Green Fluorescent Proteins; Hydrogen-Ion Concentration; Kinetics; Light; Molecular Sequence Data; Ornithine; Plant Leaves; Plant Proteins; Protein Sorting Signals; Protein Transport; Recombinant Fusion Proteins; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Temperature; Transfection | 2005 |
Metabolic fates of ammonia-N in ruminal epithelial and duodenal mucosal cells isolated from growing sheep.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Citrulline; Duodenum; Epithelium; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Intestinal Mucosa; Nitrogen; Nitrogen Isotopes; Rumen; Sheep; Urea | 2005 |
Ammonium chloride and alpha-ketoglutaric acid increase glutamine availability in the early phase of induced acute metabolic acidosis.
Topics: Acidosis; Acute Disease; Amino Acids, Branched-Chain; Ammonium Chloride; Animals; Citrulline; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Intestinal Mucosa; Ketoglutaric Acids; Liver; Muscle, Skeletal; Quaternary Ammonium Compounds; Sus scrofa; Urea | 2006 |
Arginine and urea metabolism in the liver graft: A study using microdialysis in human orthotopic liver transplantation.
Topics: Adolescent; Adult; Aged; Arginine; Brain Death; Cadaver; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Liver Transplantation; Microdialysis; Middle Aged; Ornithine; Tissue Donors; Urea | 2006 |
Acute alterations of glutamate, glutamine, GABA, and other amino acids after spinal cord contusion in rats.
Topics: Animals; Aspartic Acid; Citrulline; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Rats; Rats, Wistar; Spinal Cord Injuries; Taurine | 2007 |
Does the ornithine-alpha-ketoglutarate ratio influence ornithine alpha-ketoglutarate metabolism in healthy rats?
Topics: Animals; Arginine; Citrulline; Glutamic Acid; Intestinal Mucosa; Ketoglutaric Acids; Liver; Male; Muscle, Skeletal; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Random Allocation; Rats; Rats, Wistar | 2007 |
Paracetamol inhibits nitric oxide synthesis in murine spinal cord slices.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arginine; Caffeine; Central Nervous System Stimulants; Cerebellum; Citrulline; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; In Vitro Techniques; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Spinal Cord | 2007 |
Magnetic resonance spectroscopy in adult-onset citrullinemia: elevated glutamine levels in comatose patients.
Topics: Adult; Ammonia; Biomarkers; Brain; Brain Mapping; Cerebral Cortex; Choline; Citrulline; Citrullinemia; Coma; Diffusion Magnetic Resonance Imaging; Disease Progression; Early Diagnosis; Fatal Outcome; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Hyperammonemia; Inositol; Magnetic Resonance Spectroscopy; Male; Predictive Value of Tests | 2007 |
The 2007 ESPEN Sir David Cuthbertson Lecture: amino acids between and within organs. The glutamate-glutamine-citrulline-arginine pathway.
Topics: Amino Acids; Arginine; Citrulline; Critical Illness; Enteral Nutrition; Glutamic Acid; Glutamine; Humans; Kidney; Liver; Organ Specificity; Parenteral Nutrition | 2008 |
The intermediate role of carbamyl-L-glutamic acid in citrulline synthesis.
Topics: Citrulline; Glutamic Acid | 1948 |
Age-related changes in arginine and its metabolites in memory-associated brain structures.
Topics: Aging; Analysis of Variance; Animals; Arginase; Arginine; Brain; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memory; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley | 2009 |
Glutamate excitotoxicity mediates neuronal apoptosis after hypothermic circulatory arrest.
Topics: Animals; Apoptosis; Brain; Circulatory Arrest, Deep Hypothermia Induced; Citrulline; Dizocilpine Maleate; DNA Fragmentation; Dogs; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Glycine; In Situ Nick-End Labeling; Microdialysis; Microscopy, Electron; Necrosis; Neurons; Nitric Oxide; Reperfusion Injury | 2010 |
Arginine is synthesized from proline, not glutamate, in enterally fed human preterm neonates.
Topics: Arginine; Chromatography, Liquid; Citrulline; Enteral Nutrition; Glutamic Acid; Humans; Infant, Newborn; Infant, Premature; Isotope Labeling; Ornithine; Proline; Tandem Mass Spectrometry | 2011 |
NO-dependent protective effect of VEGF against excitotoxicity on layer VI of the developing cerebral cortex.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Calcium; Caspase 3; Cerebral Cortex; Citrulline; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agents; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Glutamic Acid; Green Fluorescent Proteins; In Vitro Techniques; L-Lactate Dehydrogenase; Mice; Mice, Transgenic; NADPH Dehydrogenase; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; RNA, Small Interfering; S-Nitroso-N-Acetylpenicillamine; Time Factors; Vascular Endothelial Growth Factor A | 2012 |
Decreased glutamate, glutamine and citrulline concentrations in plasma and muscle in endotoxemia cannot be reversed by glutamate or glutamine supplementation: a primary intestinal defect?
Topics: Administration, Oral; Animals; Anorexia; Citrulline; Dietary Supplements; Endotoxemia; Glutamic Acid; Glutamine; Interleukin-6; Intestinal Mucosa; Lipopolysaccharides; Male; Muscle, Skeletal; Rats; Rats, Wistar; Sodium Glutamate; Tumor Necrosis Factor-alpha | 2012 |
Differential effects of chronic hyperammonemia on modulation of the glutamate-nitric oxide-cGMP pathway by metabotropic glutamate receptor 5 and low and high affinity AMPA receptors in cerebellum in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blotting, Western; Chronic Disease; Citrulline; Cyclic GMP; Glutamic Acid; Hyperammonemia; Male; Nitric Oxide; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate | 2012 |
Hyperammonemia alters the modulation by different neurosteroids of the glutamate-nitric oxide-cyclic GMP pathway through NMDA- GABAA - or sigma receptors in cerebellum in vivo.
Topics: Animals; Cerebellum; Citrulline; Cyclic GMP; Extracellular Space; Glutamic Acid; Hyperammonemia; Male; N-Methylaspartate; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 2013 |
The role of NO in the posterior hypothalamus in amygdala-generated pressor responses in conscious rats.
Topics: Amygdala; Animals; Blood Pressure; Citrulline; Electric Stimulation; Enzyme Inhibitors; Female; Glutamic Acid; Heart Rate; Hypothalamus, Posterior; Male; Microdialysis; Microinjections; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 2013 |
Improvement of L-citrulline production in Corynebacterium glutamicum by ornithine acetyltransferase.
Topics: Acetyltransferases; Bacterial Proteins; Citrulline; Cloning, Molecular; Corynebacterium glutamicum; Gene Expression Regulation, Bacterial; Glutamic Acid; Metabolic Engineering; Plasmids; Recombination, Genetic | 2015 |
Altered brain arginine metabolism in schizophrenia.
Topics: Agmatine; Arginase; Arginine; Autopsy; Blotting, Western; Brain; Case-Control Studies; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citrulline; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Mass Spectrometry; Middle Aged; Nitric Oxide Synthase Type III; Ornithine; Regression Analysis; Schizophrenia | 2016 |
Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting antidepressants.
Topics: Adult; Arginine; Citrulline; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Indoleacetic Acids; Infusions, Intravenous; Ketamine; Male; Metabolomics; Methionine; Middle Aged; Ornithine; Phenotype; Phospholipids; Tryptophan; Urea | 2016 |
Further studies of the effects of aging on arginine metabolites in the rat vestibular nucleus and cerebellum.
Topics: Aging; Animals; Arginine; Cerebellum; Citrulline; Glutamic Acid; Male; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley; Vestibular Nuclei | 2017 |
l-Citrulline restores nitric oxide level and cellular uptake at the brain capillary endothelial cell line (TR-BBB cells) with glutamate cytotoxicity.
Topics: Animals; Antigens, Viral, Tumor; Blood-Brain Barrier; Capillaries; Cell Line; Cell Survival; Citrulline; Cytoprotection; Endothelial Cells; Excitatory Amino Acid Agonists; Glutamic Acid; Large Neutral Amino Acid-Transporter 1; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats, Transgenic; Simian virus 40 | 2018 |
Glutamic acid-valine-citrulline linkers ensure stability and efficacy of antibody-drug conjugates in mice.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Breast Neoplasms; Carboxylic Ester Hydrolases; Cell Line, Tumor; Citrulline; Drug Design; Drug Stability; Female; Gene Expression; Glutamic Acid; Humans; Hydrolysis; Immunoconjugates; Mice; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Receptor, ErbB-2; Survival Analysis; Valine; Xenograft Model Antitumor Assays | 2018 |
Ruminal microbes of adult steers do not degrade extracellular L-citrulline and have a limited ability to metabolize extracellular L-glutamate1,2.
Topics: Amino Acids; Ammonia; Animals; Arginine; Bacteria; Cattle; Citrulline; Glutamic Acid; Glutamine; Male; Ornithine; Proline; Rumen | 2019 |
Metabolic studies reveal that ruminal microbes of adult steers do not degrade rumen-protected or unprotected L-citrulline.
Topics: Ammonia; Animal Feed; Animals; Arginine; Cattle; Citrulline; Diet; Digestion; Edible Grain; Fermentation; Gastrointestinal Microbiome; Glutamic Acid; Glutamine; Male; Rumen | 2020 |
Substitution of high-dose sucrose with fructose in high-fat diets resulted in higher plasma concentrations of aspartic acid, cystine, glutamic acid, ornithine and phenylalanine, and higher urine concentrations of arginine and citrulline.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Blood Glucose; Citrulline; Cystine; Diet, High-Fat; Dietary Sucrose; Dietary Sugars; Fructose; Glutamic Acid; Lipids; Male; Ornithine; Phenylalanine; Rats; Rats, Wistar | 2020 |
Towards risk stratification and prediction of disease severity and mortality in COVID-19: Next generation metabolomics for the measurement of host response to COVID-19 infection.
Topics: Adult; Aged; Area Under Curve; Carnitine; Citrulline; COVID-19; Female; Glutamic Acid; Humans; Kynurenine; Male; Metabolome; Metabolomics; Middle Aged; Ornithine; Risk Factors; ROC Curve; SARS-CoV-2; Severity of Illness Index; Tryptophan | 2021 |
Serum metabolomic signatures of gestational diabetes in South Asian and white European women.
Topics: Arginine; Asian People; Canada; Citrulline; Creatinine; Diabetes, Gestational; Female; Glucose; Glutamic Acid; Glutamine; Humans; Ornithine; Pregnancy; Prospective Studies | 2022 |
Subchronic tolerance trials of graded oral supplementation with ornithine hydrochloride or citrulline in healthy adults.
Topics: Adult; Arginine; Aspartic Acid; Citrulline; Dietary Supplements; Glutamic Acid; Humans; Male; Ornithine | 2023 |
Metabolomics profiling of seminal plasma in obesity-induced asthenozoospermia.
Topics: Aconitic Acid; Alanine; Asthenozoospermia; Citrulline; Glucose; Glutamic Acid; Glycine; Humans; Leucine; Lysine; Male; Metabolomics; Phenylalanine; Proline; Semen; Serine; Succinic Acid; Threonine; Tyrosine; Valine | 2023 |
Variant in the allosteric domain of CPS1 protein associated with effectiveness of N-carbamoyl glutamate therapy in neonatal onset CPS1 deficiency.
Topics: Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase I Deficiency Disease; Citrulline; Glutamic Acid; Humans; Infant, Newborn; Urea Cycle Disorders, Inborn | 2023 |
The interaction of ammonia and manganese in abnormal metabolism of minimal hepatic encephalopathy: A comparison metabolomics study.
Topics: Alanine; Ammonia; Animals; Arginine; Brain; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Hyperammonemia; Inositol; Isoleucine; Lactic Acid; Leucine; Manganese; Metabolomics; Rats; Rats, Sprague-Dawley; Taurine | 2023 |