citrulline and cyclic gmp

citrulline has been researched along with cyclic gmp in 125 studies

Research

Studies (125)

TimeframeStudies, this research(%)All Research%
pre-19902 (1.60)18.7374
1990's73 (58.40)18.2507
2000's33 (26.40)29.6817
2010's17 (13.60)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Heuzé-Joubert, I; Laubie, M; Mennecier, P; Simonet, S; Verbeuren, TJ1
Giunta, MA; Morton, DB1
Costa, E; Kiedrowski, L; Wroblewski, JT2
Bredt, DS; Dawson, TM; Dawson, VL; London, ED; Snyder, SH1
Brenner, BM; Lamas, S; Marsden, PA; Michel, T1
Chen, PY; Sanders, PW2
Böhme, E; John, M; Mayer, B1
Knowles, RG; Moncada, S; Palacios, M; Palmer, RM1
Bredt, DS; Snyder, SH1
Byam-Smith, M; Garfield, RE; Izumi, H; Yallampalli, C1
Fujisawa, Y; Fujita, N; Hayashi, H; Okamoto, M; Shibanaka, Y; Takai, M; Umemura, I1
Beasley, D; Eldridge, M1
Clark, DA; Eloby-Childress, S; Kakkis, JL; Miller, MJ; Munshi, UK; Sadowska-Krowicka, H; Zhang, XJ1
Bing, RJ; Dudek, RR; Giesler, G; Pinto, V; Wildhirt, S1
Ambs, S; Felley-Bosco, E; Harris, CC; Keefer, LK; Lowenstein, CJ1
Absood, A; Berisha, HI; Pakbaz, H; Said, SI1
Boscá, L; González, MP; Hortelano, S; Oset-Gasque, MJ; Parramón, M1
Ma, L; Morita, I; Murota, S1
McKenna, TM; Tao, S1
el-Fakahany, EE; Hu, J; Lee, JH1
Deliconstantinos, G; Stavrides, JC; Villiotou, V2
Espinosa, J; Esteva, M; Farber, M; Flawiá, MM; Montagna, AE; Paveto, C; Pereira, C; Torres, HN1
Bosia, A; Bussolino, F; Costamagna, C; Deharo, E; Gabrielli, G; Gautret, P; Ghigo, D; Ginsburg, H; Giribaldi, G; Pescarmona, G; Todde, R; Ulliers, D1
el-Fakahany, EE; Fridlund, J; Hu, J1
Belia, S; Chiorean, M; Corinaldesi, R; De Giorgio, R; Distrutti, E; Fano, G; Fiorucci, S; Morelli, A; Santucci, L; Stanghellini, V1
De Loore, KL; Lesage, AS; Leysen, JE; Peeters, L1
Daniel, EE; Jang, E; Kostka, P; Stewart, JL; Watson, EG1
Kolb, H; Kolb-Bachofen, V; Kröncke, KD; Rodriguez, ML1
Corbett, JA; Currie, MG; Kasten, TP; McDaniel, ML; Misko, TP; Moore, WM; Nickols, GA; Tilton, RG; Williamson, JR1
Blum, G; Caramelo, C; Casado, S; Gallego, MJ; López Farré, A; Montón, M; Riesco, A1
Ma, L1
Dinger, BG; Fidone, SJ; Stensaas, LJ; Wang, ZZ1
Alberola, ML; Caramelo, C; Casado, S; Esteban, A; López-Farré, A; Millás, I; Montón, M1
de Vries, PM; Donker, AJ; Olthof, CG; Smulders, RA; Stehouwer, CD; Teerlink, T; van Kamp, GJ1
Aoki, E; Semba, R; Shoji, R; Takeuchi, IK1
Foster, HE; Smith, SD; Weiss, RM; Wheeler, MA1
Canteros, G; Genaro, A; Gimeno, M; McCann, SM; Rettori, V; Suburo, A1
Aihara, T; Ikeda, Y; Koyama, Y; Kusano, T; Muto, Y; Shiraishi, M1
Mollace, V; Nisticò, G1
Conte, A; Franchini, A; Ottaviani, E1
Nagao, T; Urushidani, T; Yamazaki, J1
Chou, SM; Komai, K; Wang, HS1
Aiello, S; Benigni, A; Boccardo, P; Donadelli, R; Lojacono, A; Noris, M; Soregaroli, M1
Chou, SM; Taniguchi, A; Wang, HS1
Contreras, R; Fuentes, O; Mann, GE; Sobrevia, L1
Johns, RA; Pajewski, TN; Rengasamy, A1
Calvo, JR; Guerrero, JM; Pozo, D; Reiter, RJ1
Aarsen, M; De Vries, PM; Donker, AJ; Smulders, RA; Stehouwer, CD; Teerlink, T; Van Kamp, GJ1
Higa, T; Hiroyasu, S; Kusano, T; Miyaguni, T; Muto, Y; Nagahama, M; Okuhama, Y; Shiraishi, M; Tomori, H1
Grider, JR; Jin, JG; Makhlouf, GM; Murthy, KS1
Danner, RL; Rafferty, SP; Wang, S; Wesley, RA; Yan, L1
Locher, R; Suter, PM; Vetter, W; Weisser, B1
Allen, JC; Husid, A; Kahn, AM; Seidel, CL; Song, T1
Mann, GE; Sobrevia, L; Yudilevich, DL1
Ayata, C; Huang, PL; Meng, W; Moskowitz, MA; Waeber, C1
Gupta, MP; Hart, CM; Steinberg, HO1
El-Fakahany, EE; Grande, AW; Hu, J; Parsons, AM; Wotta, DR1
Bina, S; Hart, JL; Muldoon, SM; Sei, Y1
Catravas, JD; Fuchs, LC; Hoque, AM; Papapetropoulos, A; Venema, RC1
Fujino, MA; Hosoda, K; Owyang, C; Takahashi, T1
Ruiz, E; Tejerina, T1
Cebral, E; Franchi, A; Gimeno, MF; Herrero, MB; Motta, A1
Fujita-Yoshigaki, J; Furuyama, S; Hara-Yokoyama, M; Michikawa, H; Mitsui, Y; Sugiya, H1
Gräbner, R; Heller, R; Münscher-Paulig, F; Till, U1
Cannavò, L; Ginoprelli, T; Ientile, R; Macaione, S; Pedale, S1
Baylis, C; Schmidt, RJ; Sorkin, MI; Tracy, TS; Yokota, S1
Del Rio, M; Ganado, P; Ruiz, E; Sanz, M; Somoza, B; Tejerina, T1
Holm, P; Kankaanranta, H; Knowles, RG; Moilanen, E; Oja, SS1
Baylis, C; Domico, J; Engels, K; Samsell, LS; Schmidt, RJ; Sorkin, MI; Tracy, TS; Yokota, S1
Aldieri, E; Anfossi, G; Bosia, A; Cavalot, F; Costamagna, C; Ghigo, D; Massucco, P; Mattiello, L; Trovati, M1
Harrisson, F; Tao, L; van Nassauw, L1
Inoue, S; Kawata, S; Kayanoki, Y; Kiso, S; Matsuzawa, Y; Tamura, S; Taniguchi, N; Yamasaki, E1
Ayala, R; Bellver, T; Casado, S; Farré, J; García-Durán, M; Gómez, J; González-Fernández, F; Guerra, JI; Jiménez, A; López-Farré, A; Mar Arriero, M; Marcos, P; Montón, M; Núñez, A; Rico, L; Romero, J; Sánchez de Miguel, L1
Chell, MJ; El-Fakahany, EE; Linden, DR; Seybold, VS1
Colasanti, M; Musci, G; Persichini, T; Polticelli, F; Venturini, G1
Heller, R; Mayer, B; Schellenberg, B; Unbehaun, A; Werner, ER; Werner-Felmayer, G1
Angielski, S; Jankowski, M; Kalinowski, L; Szczepanska-Konkel, M1
Burette, A; Petrusz, P; Schmidt, HH; Weinberg, RJ1
Fraser, T; Li, M; Turner, SW; Wang, J; Wen, C; Whitworth, JA1
de Vente, J; Graubard, K; Scholz, NL; Truman, JW1
Gräbner, R; Heller, R; Malle, E; Marsche, G; Nuszkowski, A; Unbehaun, A1
Blazy, I; Déchaux, M; Mason, NP; Rabier, D; Richalet, JP; Schneider, JC1
Andrew, P; Groschner, K; Kojda, G; Mayer, B; Schmidt, K; Schmitz, V; Schrammel, A1
Dikshit, M; Raghavan, SA1
de Vente, J; Goy, MF; Graubard, K; Labenia, JS; Scholz, NL1
Deng, A; Thomson, SC1
Grosser, N; Schröder, H1
Cao, L; Eldred, WD1
Bui, V; Kadekaro, M; Salas, N; Summy-Long, JY; Terrell, ML1
Casós, K; Farriol, M; López, D; Mitjavila, MT; Orta, X; Puig-Parellada, P; Sáiz, MP1
Evans, RW; Fernstrom, JD; Kuller, LH; Morris, SM; Thompson, J1
Bachetti, T; Bastianon, D; Bresciani, G; Callea, F; Comini, L; Curello, S; Ferrari, R; Palmieri, M1
Eldred, WD; Yu, D1
Heller, R; Werner, ER; Werner-Felmayer, G1
Bodnárová, M; Martásek, P; Moroz, LL1
Farndale, RW; Naseem, KM; Riba, R; Sharifi, M1
Fukatsu, A; Funami, J; Hayashi, T; Ignarro, LJ; Iguchi, A; Juliet, PA; Matsui-Hirai, H; Miyazaki, A1
Czp, A1
Bonz, A; Burkard, N; Cartwright, EJ; Frantz, S; Hallhuber, M; Hofmann, U; Hu, K; Kaufmann, SG; Maier, LS; Maier, SK; Neyses, L; Renné, T; Ritter, O; Rokita, AG; Schuh, K; Wu, R1
Belforte, N; Bordone, M; Cymeryng, C; Keller Sarmiento, MI; Moreno, MC; Rosenstein, RE1
Black, KL; Espinoza, AJ; Hu, J; Irvin, DK; Ko, MK; Konda, BM; Ong, JM; Sacapano, MR; Shu, Y; Wang, X; Yin, D1
Heinrich, R; Holstein, GR; Kunst, M; Weinrich, A; Wirmer, A1
Leoncini, G; Passalacqua, M; Segantin, A; Signorello, MG1
Boucher, JL; Fournet-Bourguignon, MP; Frapart, Y; Gosgnach, W; Lesage, L; Molez, S; Perrier, E; Reure, H; Royere, E; Vilaine, JP; Villeneuve, N1
Holstein, GR; Homberg, U; Schachtner, J; Siegl, T1
Felipo, V; Llansola, M1
Graier, WF; Martens-Lobenhoffer, J; Mayer, B; Meinitzer, A; Schmidt, K; Torres, CM; Venema, RC1
Bicker, G; Böger, N; Eickhoff, R; Holstein, GR; Kerssen, U; Lorbeer, C; Martinelli, GP; Stern, M; Ziegler, M1
Anderson, KL; Itzhak, Y; Kelley, JB1
de Hoon, JN; Depré, M; Van der Schueren, BJ; Van Hecken, A; Verbesselt, R; Verbrugge, FH1
Giacobbe, E; Leoncini, G; Passalacqua, M; Signorello, MG1
Aschenbrenner, K; Heinrich, R; Kunst, M; Pförtner, R1
Boix, J; Cabrera-Pastor, A; Felipo, V; Llansola, M; Reznikov, V1
Agustí, A; Cauli, O; Felipo, V; González-Usano, A1
Hayashi, T; Ina, K; Kuzuya, M; Maeda, M; Morita, M; Ochiai, M; Yamaguchi, T1
Eriksson, K; Larsson, AC; Lindholm, P; Nihlén, C; Schiffer, T; Uusijärvi, J; Weitzberg, E1
He, GW; Liu, Z; Lun, LM; Ning, CP; Wang, HW; Wang, J; Xuan, C; Zhang, BB; Zhao, JX1
Andre, T; McKinley-Barnard, S; Morita, M; Willoughby, DS1
Ishii, K; Kamimura, A; Kurauchi, Y; Mokudai, K; Mori, A; Morita, M; Nakahara, T; Sakamoto, K1
Abraham, A; Artaza, JN; Ferrini, MG; Garcia, E; Nguyen, S; Rajfer, J1
Arenas, YM; Cabrera-Pastor, A; Felipo, V; Montoliu, C; Taoro-Gonzalez, L1
Abraham, A; Artaza, JN; Ferrini, MG; Flores, M; Graciano, L; Luna, R; Nguyen, S; Rajfer, J1

Reviews

3 review(s) available for citrulline and cyclic gmp

ArticleYear
Release of nitric oxide from astroglial cells: a key mechanism in neuroimmune disorders.
    Advances in neuroimmunology, 1995, Volume: 5, Issue:4

    Topics: Animals; Arginine; Citrulline; Cyclic GMP; Invertebrates; NADP; Nerve Tissue Proteins; Nervous System; Neuronal Plasticity; Nitric Oxide; Nitric Oxide Synthase; Signal Transduction; Smell; Species Specificity

1995
Nitric oxide: an ancestral immunocyte effector molecule.
    Advances in neuroimmunology, 1995, Volume: 5, Issue:4

    Topics: Animals; Cardiovascular Diseases; Cell Adhesion; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Humans; Infections; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Vasodilation

1995
Chronic hyperammonemia alters extracellular glutamate, glutamine and GABA and membrane expression of their transporters in rat cerebellum. Modulation by extracellular cGMP.
    Neuropharmacology, 2019, 12-15, Volume: 161

    Topics: Animals; Cell Membrane; Cerebellum; Citrulline; Cyclic GMP; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hyperammonemia; Male; Neurotransmitter Transport Proteins; Rats; Rats, Wistar; Synaptic Transmission

2019

Trials

4 trial(s) available for citrulline and cyclic gmp

ArticleYear
Haemodynamic and biochemical responses to L-arginine and L-lysine infusions in normal subjects: L-arginine-induced vasodilatation cannot be explained by non-specific effects of cationic amino acids.
    Clinical science (London, England : 1979), 1997, Volume: 92, Issue:4

    Topics: Adult; Arginine; Atrial Natriuretic Factor; Blood Pressure; Citrulline; Cyclic GMP; Electrolytes; Extracellular Space; Female; Heart Rate; Humans; Lysine; Male; Nitric Oxide; Vascular Resistance; Vasodilation

1997
Indices of activity of the nitric oxide system in hemodialysis patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1999, Volume: 34, Issue:2

    Topics: Arginine; Blood Pressure; Citrulline; Cyclic GMP; Diet; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Renal Dialysis; Second Messenger Systems

1999
No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers.
    Cephalalgia : an international journal of headache, 2010, Volume: 30, Issue:11

    Topics: Area Under Curve; Arginine; Biomarkers; Citrulline; Cyclic GMP; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites

2010
Combined L-citrulline and glutathione supplementation increases the concentration of markers indicative of nitric oxide synthesis.
    Journal of the International Society of Sports Nutrition, 2015, Volume: 12

    Topics: Adolescent; Adult; Animals; Arginine; Biomarkers; Body Mass Index; Citrulline; Cyclic GMP; Dietary Supplements; Double-Blind Method; Glutathione; Healthy Volunteers; Human Umbilical Vein Endothelial Cells; Humans; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Resistance Training; Young Adult

2015

Other Studies

118 other study(ies) available for citrulline and cyclic gmp

ArticleYear
Effect of vasodilators, including nitric oxide, on the release of cGMP and cAMP in the isolated perfused rat kidney.
    European journal of pharmacology, 1992, Sep-22, Volume: 220, Issue:2-3

    Topics: Acetylcholine; Animals; Atrial Natriuretic Factor; Citrulline; Colforsin; Cyclic AMP; Cyclic GMP; Epoprostenol; Kidney; Male; Methoxamine; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Rats; Rats, Wistar; Serotonin; Vasoconstriction; Vasodilation; Vasodilator Agents

1992
Eclosion hormone stimulates cyclic GMP levels in Manduca sexta nervous tissue via arachidonic acid metabolism with little or no contribution from the production of nitric oxide.
    Journal of neurochemistry, 1992, Volume: 59, Issue:4

    Topics: Animals; Arachidonic Acid; Citrulline; Cyclic GMP; Guanylate Cyclase; In Vitro Techniques; Insect Hormones; Moths; Nerve Tissue; Nitric Oxide; Solubility

1992
Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells.
    Journal of neurochemistry, 1992, Volume: 58, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Granulocytes; Kainic Acid; N-Methylaspartate; Nitric Oxide Synthase; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter

1992
In vitro interaction between cerebellar astrocytes and granule cells: a putative role for nitric oxide.
    Neuroscience letters, 1992, Jan-20, Volume: 135, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Astrocytes; Calcimycin; Cell Communication; Cells, Cultured; Cerebellum; Citrulline; Cyclic GMP; Kinetics; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats

1992
Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Jul-15, Volume: 88, Issue:14

    Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Dizocilpine Maleate; Fetus; Glutamates; Hemoglobins; Hippocampus; Kinetics; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase

1991
Nitric oxide synthesis in endothelial cells: evidence for a pathway inducible by TNF-alpha.
    The American journal of physiology, 1991, Volume: 261, Issue:4 Pt 1

    Topics: Animals; Aorta; Arginine; Citrulline; Cyclic GMP; Endothelium, Vascular; Glomerular Mesangium; Lipopolysaccharides; Nitric Oxide; Renal Artery; Tumor Necrosis Factor-alpha

1991
L-arginine abrogates salt-sensitive hypertension in Dahl/Rapp rats.
    The Journal of clinical investigation, 1991, Volume: 88, Issue:5

    Topics: Animals; Arginine; Blood Pressure; Citrulline; Cyclic GMP; Glomerular Filtration Rate; Hypertension; Nitric Oxide; omega-N-Methylarginine; Rats; Sodium Chloride

1991
Purification of a Ca2+/calmodulin-dependent nitric oxide synthase from porcine cerebellum. Cofactor-role of tetrahydrobiopterin.
    FEBS letters, 1990, Dec-17, Volume: 277, Issue:1-2

    Topics: Amino Acid Oxidoreductases; Animals; Biopterins; Calcium; Calmodulin; Cerebellum; Citrulline; Cyclic GMP; Guanylate Cyclase; Molecular Weight; Nitric Oxide Synthase; Swine

1990
Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:13

    Topics: Animals; Arginine; Brain; Citrulline; Cyclic GMP; Cytosol; Guanylate Cyclase; Kinetics; Male; Nitric Oxide; Rats; Signal Transduction; Synaptosomes

1989
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:22

    Topics: Animals; Arginine; Aspartic Acid; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quisqualic Acid; Rats

1989
Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:6

    Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Citrulline; Cyclic GMP; Dexamethasone; Disease Models, Animal; Homoarginine; Hypertension; Insulin; Male; Nitrates; Nitric Oxide; Ornithine; Rats; Rats, Inbred Strains

1993
An L-arginine-nitric oxide-cyclic guanosine monophosphate system exists in the uterus and inhibits contractility during pregnancy.
    American journal of obstetrics and gynecology, 1994, Volume: 170, Issue:1 Pt 1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Culture Techniques; Cyclic GMP; Dose-Response Relationship, Drug; Female; Labor, Obstetric; Methylene Blue; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Pregnancy; Progesterone; Rats; Rats, Sprague-Dawley; Uterine Contraction; Uterus

1994
Eclosion hormone-mediated signal transduction in the silkworm abdominal ganglia: involvement of a cascade from inositol(1,4,5)trisphosphate to cyclic GMP.
    Biochemical and biophysical research communications, 1994, Jan-28, Volume: 198, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bombyx; Calcium; Citrulline; Cyclic GMP; Egtazic Acid; Enzyme Activation; Ganglia, Invertebrate; Inositol 1,4,5-Trisphosphate; Insect Hormones; Neomycin; Nitric Oxide Synthase; Nitroarginine; p-Methoxy-N-methylphenethylamine; Second Messenger Systems; Signal Transduction; Sulfonamides

1994
Interleukin-1 beta and tumor necrosis factor-alpha synergistically induce NO synthase in rat vascular smooth muscle cells.
    The American journal of physiology, 1994, Volume: 266, Issue:4 Pt 2

    Topics: Amino Acid Oxidoreductases; Animals; Cells, Cultured; Citrulline; Cyclic GMP; Drug Synergism; Enzyme Induction; Gene Expression; Interleukin-1; Lipopolysaccharides; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitrites; Rats; Recombinant Proteins; Tumor Necrosis Factor-alpha

1994
Inhibition of calcium-dependent nitric oxide synthase causes ileitis and leukocytosis in guinea pigs.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:6

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Cyclic GMP; Female; Guanidines; Guinea Pigs; Ileitis; Leukocyte Count; Leukocytosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peroxidase

1994
Dexamethasone inhibits the expression of an inducible nitric oxide synthase in infarcted rabbit myocardium.
    Biochemical and biophysical research communications, 1994, Jul-29, Volume: 202, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Coronary Vessels; Cyclic GMP; Dexamethasone; Ligation; Male; Myocardial Infarction; Myocardium; Nitric Oxide Synthase; Rabbits

1994
Constitutive expression of inducible nitric oxide synthase in human bronchial epithelial cells induces c-fos and stimulates the cGMP pathway.
    American journal of respiratory cell and molecular biology, 1994, Volume: 11, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Antigens, Polyomavirus Transforming; Arginine; Base Sequence; Blotting, Northern; Bronchi; Carbon Radioisotopes; Cell Division; Cell Line, Transformed; Citrulline; Cyclic GMP; DNA Primers; Enzyme Induction; Epithelium; Gene Expression; Genes, fos; Humans; Kinetics; Mice; Molecular Sequence Data; Nitric Oxide Synthase; Polymerase Chain Reaction; Proto-Oncogene Proteins c-fos; Simian virus 40; Transfection

1994
Nitric oxide as a mediator of oxidant lung injury due to paraquat.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Aug-02, Volume: 91, Issue:16

    Topics: Amino Acid Oxidoreductases; Animals; Calcium; Citrulline; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Lung Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidants; Paraquat; Perfusion; Respiration

1994
Nitric oxide implication in the control of neurosecretion by chromaffin cells.
    Journal of neurochemistry, 1994, Volume: 63, Issue:5

    Topics: Amino Acid Oxidoreductases; Animals; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Citrulline; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Inositol 1,4,5-Trisphosphate; NADPH Dehydrogenase; Neurosecretion; Nicotine; Nitric Oxide; Nitric Oxide Synthase

1994
Presence of constitutive type nitric oxide synthase in cultured astrocytes isolated from rat cerebra.
    Neuroscience letters, 1994, Jun-20, Volume: 174, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Astrocytes; Brain; Cells, Cultured; Citrulline; Cyclic GMP; Histocytochemistry; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats

1994
In vitro endotoxin exposure induces contractile dysfunction in adult rat cardiac myocytes.
    The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Dactinomycin; Electric Stimulation; Endotoxins; Heart; Kinetics; Male; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitroprusside; Rats; Rats, Sprague-Dawley; Time Factors

1994
Inhibition of neuronal nitric oxide synthase by antipsychotic drugs.
    Psychopharmacology, 1994, Volume: 114, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Antipsychotic Agents; Arginine; Brain Neoplasms; Calmodulin; Cerebellum; Citrulline; Cyclic GMP; Cytosol; In Vitro Techniques; Male; Mice; Neuroblastoma; Neurons; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured

1994
Modulation of particulate nitric oxide synthase activity and peroxynitrite synthesis in cholesterol enriched endothelial cell membranes.
    Biochemical pharmacology, 1995, May-26, Volume: 49, Issue:11

    Topics: Amino Acid Oxidoreductases; Animals; Cattle; Cell Membrane; Cholesterol; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Manganese; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Superoxides

1995
The nitric oxide transduction pathway in Trypanosoma cruzi.
    The Journal of biological chemistry, 1995, Jul-14, Volume: 270, Issue:28

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Cyclic GMP; Dizocilpine Maleate; Guanylate Cyclase; Nitric Oxide; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate; Trypanosoma cruzi

1995
Erythrocyte stages of Plasmodium falciparum exhibit a high nitric oxide synthase (NOS) activity and release an NOS-inducing soluble factor.
    The Journal of experimental medicine, 1995, Sep-01, Volume: 182, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Factors; Canavanine; Cell Adhesion; Cells, Cultured; Citrulline; Culture Media, Conditioned; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; Erythrocytes; Host-Parasite Interactions; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Plasmodium; Plasmodium falciparum; Protozoan Proteins; Species Specificity; Umbilical Veins

1995
Regulation of neuronal nitric oxide synthase by histone, protamine, and myelin basic protein.
    Neurochemical research, 1995, Volume: 20, Issue:4

    Topics: Amino Acid Oxidoreductases; Animals; Binding, Competitive; Calcium; Citrulline; Cyclic GMP; Cytosol; Histones; Myelin Basic Protein; Nerve Tissue Proteins; Neuroblastoma; Neurons; Nitric Oxide Synthase; Protamines; Rats; Stimulation, Chemical; Tumor Cells, Cultured

1995
Nitric oxide modulates pepsinogen secretion induced by calcium-mediated agonist in guinea pig gastric chief cells.
    Gastroenterology, 1995, Volume: 109, Issue:4

    Topics: Animals; Arginine; Calcium; Calmodulin; Carbachol; Cells, Cultured; Cholecystokinin; Citrulline; Cyclic GMP; Egtazic Acid; Gastric Mucosa; Gastrins; Guinea Pigs; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pepsinogens; Terpenes; Thapsigargin

1995
Neuroprotective sigma ligands interfere with the glutamate-activated NOS pathway in hippocampal cell culture.
    Synapse (New York, N.Y.), 1995, Volume: 20, Issue:2

    Topics: Animals; Cells, Cultured; Citrulline; Cyclic GMP; Glutamic Acid; Hippocampus; Ligands; Neuroprotective Agents; Nitric Oxide Synthase; Radioligand Assay; Rats

1995
Nitric oxide synthase in the autonomic nervous system of canine ileum.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Autonomic Nervous System; Calcium; Citrulline; Cyclic GMP; Dogs; Guanylate Cyclase; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Subcellular Fractions; Synaptosomes; Tritium

1993
Cytotoxicity of activated rat macrophages against syngeneic islet cells is arginine-dependent, correlates with citrulline and nitrite concentrations and is identical to lysis by the nitric oxide donor nitroprusside.
    Diabetologia, 1993, Volume: 36, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Female; Islets of Langerhans; Kinetics; Macrophage Activation; Macrophages; Male; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Thionucleotides

1993
Selective inhibition of the inducible nitric oxide synthase by aminoguanidine.
    European journal of pharmacology, 1993, Mar-16, Volume: 233, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Guanidines; Macrophages; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence

1993
Nitric oxide-generating system as an autocrine mechanism in human polymorphonuclear leucocytes.
    The Biochemical journal, 1993, Jun-15, Volume: 292 ( Pt 3)

    Topics: 1-Methyl-3-isobutylxanthine; Arginine; Biological Transport; Citrulline; Cyclic GMP; Endothelins; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroprusside; omega-N-Methylarginine

1993
Evidence for nitric oxide-generator cells in the brain.
    The Bulletin of Tokyo Medical and Dental University, 1993, Volume: 40, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Astrocytes; Brain; Calcium; Cerebellum; Citrulline; Cyclic GMP; Endothelium, Vascular; Neurons; Nitric Oxide; Nitric Oxide Synthase; Olfactory Bulb; Rats

1993
Nitric oxide mediates chemoreceptor inhibition in the cat carotid body.
    Neuroscience, 1995, Volume: 65, Issue:1

    Topics: Animals; Arginine; Carotid Body; Cats; Chemoreceptor Cells; Citrulline; Cyclic GMP; Electric Stimulation; Evoked Potentials; Hypoxia; Immunohistochemistry; Nitric Oxide

1995
Effects of aspirin on platelet-neutrophil interactions. Role of nitric oxide and endothelin-1.
    Circulation, 1995, Apr-01, Volume: 91, Issue:7

    Topics: Animals; Aspirin; Blood Platelets; Calcium; Citrulline; Cyclic GMP; Endothelins; Humans; In Vitro Techniques; Neutrophils; Nitric Oxide; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Rabbits

1995
Plasma endothelin levels and vascular effects of intravenous L-arginine infusion in subjects with uncomplicated insulin-dependent diabetes mellitus.
    Clinical science (London, England : 1979), 1994, Volume: 87, Issue:1

    Topics: Adult; Arginine; Atrial Natriuretic Factor; Blood Pressure; Citrulline; Cyclic GMP; Diabetes Mellitus, Type 1; Endothelins; Extracellular Space; Humans; Infusions, Intravenous; Male; Nitric Oxide; Sodium Chloride

1994
Localization of nitric oxide-related substances in the peripheral nervous tissues.
    Brain research, 1993, Aug-20, Volume: 620, Issue:1

    Topics: Animals; Arginine; Citrulline; Cyclic GMP; Ganglia, Spinal; Histocytochemistry; Immunohistochemistry; Intestines; Male; NADPH Dehydrogenase; Nitric Oxide; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Tissue Distribution

1993
Urinary nitric oxide synthase activity and cyclic GMP levels are decreased with interstitial cystitis and increased with urinary tract infections.
    The Journal of urology, 1996, Volume: 155, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Child; Child, Preschool; Citrulline; Cyclic GMP; Cystitis, Interstitial; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Radioimmunoassay; Urinary Tract Infections

1996
Nitric oxide synthase content of hypothalamic explants: increase by norepinephrine and inactivated by NO and cGMP.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Apr-30, Volume: 93, Issue:9

    Topics: Animals; Arginine; Carbon Radioisotopes; Citrulline; Cyclic GMP; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Kinetics; Male; Models, Neurological; Nerve Fibers; Neurons; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; Organ Culture Techniques; Rats; Rats, Wistar

1996
Protection against hepatic ischemia/reperfusion injury by exogenous L-arginine.
    Transplantation proceedings, 1996, Volume: 28, Issue:3

    Topics: Animals; Arginine; Citrulline; Cyclic GMP; Liver; Liver Circulation; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion; Reperfusion Injury

1996
Barium activates rat cerebellar nitric oxide synthase.
    Japanese journal of pharmacology, 1996, Volume: 70, Issue:4

    Topics: Animals; Arginine; Barium; Calcium; Calmodulin; Cerebellum; Chromatography, Ion Exchange; Citrulline; Cyclic GMP; Enzyme Activation; Lethal Dose 50; Male; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1996
Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: an immunohistochemical study.
    Journal of chemical neuroanatomy, 1996, Volume: 10, Issue:3-4

    Topics: Amyotrophic Lateral Sclerosis; Citrulline; Cyclic GMP; Cytoplasm; Humans; Immunohistochemistry; Motor Neurons; Neurofilament Proteins; Nitrates; Nitric Oxide; Nitrogen; Oxidation-Reduction; Superoxide Dismutase; Tyrosine

1996
Systemic and fetal-maternal nitric oxide synthesis in normal pregnancy and pre-eclampsia.
    British journal of obstetrics and gynaecology, 1996, Volume: 103, Issue:9

    Topics: Adult; Arginine; Blood Platelets; Blotting, Northern; Citrulline; Cyclic GMP; Female; Humans; Nitric Oxide; Nitric Oxide Synthase; Pre-Eclampsia; Pregnancy

1996
Role of SOD-1 and nitric oxide/cyclic GMP cascade on neurofilament aggregation in ALS/MND.
    Journal of the neurological sciences, 1996, Volume: 139 Suppl

    Topics: Aged; Amyotrophic Lateral Sclerosis; Axons; Calmodulin; Citrulline; Cyclic GMP; Female; Humans; Inclusion Bodies; Male; Microscopy, Electron; Middle Aged; Motor Neurons; Neurofilament Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitrogen Compounds; Superoxide Dismutase; Tyrosine; Ubiquitins

1996
Increase of particulate nitric oxide synthase activity and peroxynitrite synthesis in UVB-irradiated keratinocyte membranes.
    The Biochemical journal, 1996, Dec-15, Volume: 320 ( Pt 3)

    Topics: Allosteric Regulation; Calcium; Calmodulin; Cell Membrane; Citrulline; Cyclic GMP; Fluorescence Polarization; Guanylate Cyclase; Humans; Keratinocytes; Kinetics; Microsomes; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Reactive Oxygen Species; Temperature; Ultraviolet Rays

1996
Diabetes and insulin-induced stimulation of L-arginine transport and nitric oxide synthesis in rabbit isolated gastric glands.
    The Journal of physiology, 1997, Feb-01, Volume: 498 ( Pt 3)

    Topics: Animals; Arginine; Citrulline; Cyclic GMP; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Exocrine Glands; Gastric Mucosa; Hypoglycemic Agents; Insulin; Kinetics; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rabbits

1997
Inhalational anesthetic effects on rat cerebellar nitric oxide and cyclic guanosine monophosphate production.
    Anesthesiology, 1997, Volume: 86, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Arginine; Cerebellum; Citrulline; Cyclic GMP; Drug Interactions; Excitatory Amino Acid Agonists; Halothane; Isoflurane; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Tritium

1997
Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin.
    Journal of cellular biochemistry, 1997, Jun-01, Volume: 65, Issue:3

    Topics: Animals; Arginine; Calmodulin; Cerebellum; Citrulline; Cyclic GMP; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Kinetics; Male; Melatonin; Nitric Oxide Synthase; Rats; Rats, Wistar

1997
Role of exogenous L-arginine in hepatic ischemia-reperfusion injury.
    The Journal of surgical research, 1997, Volume: 69, Issue:2

    Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Citrulline; Cyclic GMP; Female; Hemodynamics; Liver; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Reperfusion Injury; Swine; Time Factors

1997
Characterization of PACAP receptors and signaling pathways in rabbit gastric muscle cells.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1

    Topics: Adenylate Cyclase Toxin; Alkaloids; Aminoquinolines; Animals; Calcium; Carbazoles; Cells, Cultured; Citrulline; Cyclic AMP; Cyclic GMP; Cytosol; Enzyme Inhibitors; GTP-Binding Proteins; Guanylate Cyclase; Indoles; Isoquinolines; Kinetics; Muscle Relaxation; Muscle, Smooth; Neuropeptides; Neurotransmitter Agents; Nifedipine; Nitric Oxide Synthase; Nitroarginine; Pertussis Toxin; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Kinase Inhibitors; Rabbits; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Signal Transduction; Stomach; Sulfonamides; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella

1997
Endogenously produced nitric oxide increases tumor necrosis factor-alpha production in transfected human U937 cells.
    Blood, 1997, Aug-01, Volume: 90, Issue:3

    Topics: Animals; Arginine; Cell Differentiation; Citrulline; Cyclic GMP; DNA, Complementary; Enzyme Induction; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Lymphoma, Large B-Cell, Diffuse; Mice; Neoplasm Proteins; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Recombinant Fusion Proteins; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1997
Low-density lipoprotein-induced formation of nitric oxide by cultured vascular smooth muscle cells of the rat.
    European journal of clinical investigation, 1997, Volume: 27, Issue:7

    Topics: Animals; Cells, Cultured; Citrulline; Cyclic GMP; Female; Humans; Lipoproteins, LDL; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Thymidine

1997
Insulin acutely inhibits cultured vascular smooth muscle cell contraction by a nitric oxide synthase-dependent pathway.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:4

    Topics: Animals; Cells, Cultured; Citrulline; Cyclic GMP; Dogs; Female; Insulin; Male; Manganese; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Vasoconstriction

1997
Elevated D-glucose induces insulin insensitivity in human umbilical endothelial cells isolated from gestational diabetic pregnancies.
    The Journal of physiology, 1998, Jan-01, Volume: 506 ( Pt 1)

    Topics: Amino Acids; Antimetabolites; Arginine; Calcium; Citrulline; Cyclic GMP; Deoxyglucose; Endothelium, Vascular; Epoprostenol; Female; Glucose; Humans; Insulin Resistance; Membrane Potentials; Onium Compounds; Organophosphorus Compounds; Pregnancy; Pregnancy in Diabetics; Umbilical Veins

1998
Neuronal NOS-cGMP-dependent ACh-induced relaxation in pial arterioles of endothelial NOS knockout mice.
    The American journal of physiology, 1998, Volume: 274, Issue:2

    Topics: Acetylcholine; Animals; Arginine; Arterioles; Autoradiography; Brain; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Indazoles; Mice; Mice, Knockout; Neurons; Nitric Oxide Synthase; Pia Mater; Quinuclidinyl Benzilate; Receptors, Muscarinic; Vasodilation

1998
H2O2 causes endothelial barrier dysfunction without disrupting the arginine-nitric oxide pathway.
    The American journal of physiology, 1998, Volume: 274, Issue:4

    Topics: Animals; Arginine; Capillary Permeability; Cells, Cultured; Citrulline; Cyclic GMP; Endothelium, Vascular; Hydrogen Peroxide; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Pulmonary Artery; Swine

1998
M1 muscarinic receptors stimulate rapid and prolonged phases of neuronal nitric oxide synthase activity: involvement of different calcium pools.
    Journal of neurochemistry, 1998, Volume: 71, Issue:2

    Topics: Acetylcholine; Animals; Calcium; Carbachol; Chelating Agents; CHO Cells; Citrulline; Cricetinae; Cyclic GMP; Dinucleoside Phosphates; Egtazic Acid; Enzyme Activation; Humans; Kinetics; Muscarinic Agonists; Mutagenesis; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Signal Transduction; Transfection; Tritium

1998
Factors contributing to differences in the regulation of cGMP in isolated porcine pulmonary vessels.
    European journal of pharmacology, 1998, Jun-19, Volume: 351, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Blotting, Western; Carbon Radioisotopes; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Female; Guanylate Cyclase; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Pulmonary Veins; Purinones; Swine

1998
Effects of antisense oligonucleotide to iNOS on hemodynamic and vascular changes induced by LPS.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Animals; Aorta; Arginine; Citrulline; Cyclic GMP; Enzyme Inhibitors; Hemodynamics; Lipopolysaccharides; Lung; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Norepinephrine; Oligonucleotides, Antisense; Rats; Rats, Wistar; RNA, Messenger

1998
Inhibitory effects of nitric oxide donors on nitric oxide synthesis in rat gastric myenteric plexus.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:3

    Topics: Animals; Calcium Channels; Citrulline; Cyclic GMP; Dose-Response Relationship, Drug; Gastric Mucosa; Male; Molsidomine; Muscle Relaxation; Myenteric Plexus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley; Stomach; Vasoactive Intestinal Peptide

1998
Relaxant effects of L-citrulline in rabbit vascular smooth muscle.
    British journal of pharmacology, 1998, Volume: 125, Issue:1

    Topics: Animals; Aorta; Cells, Cultured; Citrulline; Cyclic GMP; Dexamethasone; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Polysaccharides; Potassium Channels; Purinones; Quinoxalines; Rabbits

1998
Progesterone enhances prostaglandin E2 production via interaction with nitric oxide in the mouse acrosome reaction.
    Biochemical and biophysical research communications, 1998, Nov-18, Volume: 252, Issue:2

    Topics: Acrosome Reaction; Animals; Arginine; Citrulline; Cyclic GMP; Dinoprostone; Enzyme Inhibitors; Exocytosis; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Progesterone; Spermatozoa

1998
cGMP production is coupled to Ca(2+)-dependent nitric oxide generation in rabbit parotid acinar cells.
    Cell calcium, 1998, Volume: 23, Issue:6

    Topics: Aminoquinolines; Animals; Arginine; Calcimycin; Calcium; Citrulline; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Methacholine Chloride; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Parotid Gland; Rabbits; Receptors, Muscarinic; Thapsigargin; Time Factors

1998
L-Ascorbic acid potentiates nitric oxide synthesis in endothelial cells.
    The Journal of biological chemistry, 1999, Mar-19, Volume: 274, Issue:12

    Topics: Antioxidants; Ascorbic Acid; Biopterins; Calcium; Cells, Cultured; Citrulline; Cyclic GMP; Drug Synergism; Endothelium, Vascular; Enzyme Induction; Free Radicals; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III

1999
Intracellular polyamine levels are involved in NMDA-evoked nitric oxide production in chick retina cells.
    Journal of neurochemistry, 1999, Volume: 72, Issue:4

    Topics: Animals; Arginine; Cells, Cultured; Chick Embryo; Citrulline; Cyclic GMP; Eflornithine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; N-Methylaspartate; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Polyamines; Receptors, N-Methyl-D-Aspartate; Retina; Spermidine

1999
Nitric oxide production is low in end-stage renal disease patients on peritoneal dialysis.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Adult; Aged; Arginine; Citrulline; Creatinine; Cyclic GMP; Female; Humans; Hypertension, Renal; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Peritoneal Dialysis

1999
L-Citrulline, the by-product of nitric oxide synthesis, decreases vascular smooth muscle cell proliferation.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:1

    Topics: Animals; Aorta, Thoracic; Cell Count; Cell Cycle; Cell Division; Cells, Cultured; Citrulline; Cyclic GMP; DNA; Guanylate Cyclase; Muscle, Smooth, Vascular; Nitric Oxide; Rats

1999
No detectable NO synthesis from L-arginine or N(G)-hydroxy-L-arginine in fMLP-stimulated human blood neutrophils despite production of nitrite, nitrate, and citrulline from N(G)-hydroxy-L-arginine.
    Journal of leukocyte biology, 1999, Volume: 66, Issue:1

    Topics: Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Nitroarginine

1999
Human vascular smooth muscle cells express a constitutive nitric oxide synthase that insulin rapidly activates, thus increasing guanosine 3':5'-cyclic monophosphate and adenosine 3':5'-cyclic monophosphate concentrations.
    Diabetologia, 1999, Volume: 42, Issue:7

    Topics: Calcium; Cells, Cultured; Citrulline; Cyclic AMP; Cyclic GMP; Gene Expression; Humans; Insulin; Ionomycin; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; RNA, Messenger; Transcription, Genetic

1999
Localization of nitric oxide-related substances in the quail ovary during folliculogenesis.
    The Histochemical journal, 1999, Volume: 31, Issue:7

    Topics: Animals; Citrulline; Coturnix; Cyclic GMP; Female; Isoenzymes; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Ovarian Follicle; Ovary; Tyrosine

1999
Reduced nitric oxide production by L-arginine deficiency in lysinuric protein intolerance exacerbates intravascular coagulation.
    Metabolism: clinical and experimental, 1999, Volume: 48, Issue:9

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Antithrombin III; Arginine; Blood Coagulation Disorders; Citrulline; Cyclic GMP; Humans; Lysine; Male; Nitric Oxide; Nitroglycerin; Ornithine; Peptide Hydrolases; Platelet Aggregation; Thrombosis

1999
[The effect of triflusal on human platelet aggregation and secretion: the role of nitric oxide].
    Revista espanola de cardiologia, 2000, Volume: 53, Issue:2

    Topics: Adult; Blood Platelets; Citrulline; Cyclic GMP; Guanosine Monophosphate; Humans; Neutrophils; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Salicylates; Transforming Growth Factor beta

2000
Neurokinin(3) receptors couple to the activation of neuronal nitric-oxide synthase in stably transfected Chinese hamster ovary cells.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:2

    Topics: Animals; Calcium; Calcium Signaling; Cell Line; CHO Cells; Citrulline; Cricetinae; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Humans; Immunohistochemistry; Inositol Phosphates; Neurokinin B; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Piperidines; Rats; Receptors, Neurokinin-3; Transfection

2000
Modulation of the nitric oxide pathway by copper in glial cells.
    Biochemical and biophysical research communications, 2000, Sep-07, Volume: 275, Issue:3

    Topics: Animals; Arginine; Citrulline; Copper; Cyclic GMP; Gene Expression Regulation, Enzymologic; Interferon-gamma; Isoenzymes; Lipopolysaccharides; Neuroglia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Rats; RNA, Messenger; Tumor Cells, Cultured

2000
L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin.
    The Journal of biological chemistry, 2001, Jan-05, Volume: 276, Issue:1

    Topics: Ascorbic Acid; Biopterins; Cells, Cultured; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; GTP Cyclohydrolase; Humans; Hypoxanthines; Nitric Oxide; Nitric Oxide Synthase; Phosphorus-Oxygen Lyases; Pteridines; Pterins; RNA, Messenger; Solutions; Umbilical Cord

2001
Cyclic GMP-dependent relaxation of isolated rat renal glomeruli induced by extracellular ATP.
    The Journal of physiology, 2001, Jan-01, Volume: 530, Issue:Pt 1

    Topics: Adenosine Triphosphate; Animals; Citrulline; Cyclic GMP; Enzyme Inhibitors; Extracellular Space; Guanylate Cyclase; In Vitro Techniques; Inulin; Kidney Glomerulus; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Rats; Rats, Wistar; Receptors, Purinergic P2

2001
Immunohistochemical localization of nitric oxide synthase and soluble guanylyl cyclase in the ventral cochlear nucleus of the rat.
    The Journal of comparative neurology, 2001, Feb-26, Volume: 431, Issue:1

    Topics: Animals; Citrulline; Cochlear Nucleus; Cyclic GMP; Guanylate Cyclase; Immunohistochemistry; Male; Neurons; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Signal Transduction

2001
L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat.
    Blood pressure, 2000, Volume: 9, Issue:5

    Topics: Adrenocorticotropic Hormone; Amino Acids; Animals; Arginine; Citrulline; Cyclic GMP; Drug Evaluation; Hypertension; Male; Nitrates; Nitric Oxide; Nitrites; Random Allocation; Rats; Rats, Sprague-Dawley; Stereoisomerism

2000
Neural network partitioning by NO and cGMP.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Mar-01, Volume: 21, Issue:5

    Topics: Animals; Arginine; Brachyura; Citrulline; Cyclic GMP; Digestive System; Enzyme Inhibitors; Fluorescent Dyes; Ganglia, Invertebrate; Guanylate Cyclase; Immunohistochemistry; In Vitro Techniques; Isoquinolines; Male; Nerve Net; Neurons; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Donors; Periodicity; Signal Transduction

2001
Hypochlorite-modified low density lipoprotein inhibits nitric oxide synthesis in endothelial cells via an intracellular dislocalization of endothelial nitric-oxide synthase.
    The Journal of biological chemistry, 2001, Apr-27, Volume: 276, Issue:17

    Topics: Antioxidants; Arginine; Biopterins; Blotting, Western; Cell Membrane; Cells, Cultured; Centrifugation, Density Gradient; Citrulline; Cyclic GMP; Cyclodextrins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Golgi Apparatus; Humans; Hypochlorous Acid; Immunoblotting; Immunohistochemistry; Ionomycin; Ionophores; Lipoproteins, LDL; Microscopy, Fluorescence; Myristic Acids; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Palmitic Acids; Precipitin Tests; RNA, Messenger; Subcellular Fractions; Sucrose; Time Factors; Umbilical Veins

2001
Response of nitric oxide pathway to L-arginine infusion at the altitude of 4,350 m.
    The European respiratory journal, 2001, Volume: 18, Issue:2

    Topics: Adult; Altitude; Altitude Sickness; Arginine; Citrulline; Cyclic GMP; Female; Humans; Hypoxia; Infusions, Intravenous; Linear Models; Male; Nitric Oxide; Oxygen; Radioimmunoassay; Reference Values; Time Factors

2001
Comparison of neuronal and endothelial isoforms of nitric oxide synthase in stably transfected HEK 293 cells.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:5

    Topics: Calcium Chloride; Cell Line; Citrulline; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; Humans; Ionomycin; Ionophores; Kidney; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Solubility; Thapsigargin; Transfection; Tritium

2001
L-citrulline mediated relaxation in the control and lipopolysaccharide-treated rat aortic rings.
    European journal of pharmacology, 2001, Nov-09, Volume: 431, Issue:1

    Topics: Animals; Aorta; Arginine; Citrulline; Corticosterone; Cyclic GMP; Cycloheximide; Glutamine; Guanidines; In Vitro Techniques; Lipopolysaccharides; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilation

2001
Expression of nitric oxide synthase and nitric oxide-sensitive guanylate cyclase in the crustacean cardiac ganglion.
    The Journal of comparative neurology, 2002, Dec-09, Volume: 454, Issue:2

    Topics: Animals; Biological Clocks; Brachyura; Cerebellum; Citrulline; Cyclic GMP; Enzyme Inhibitors; Ganglia, Invertebrate; Guanylate Cyclase; Heart; In Vitro Techniques; Male; Motor Neurons; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Signal Transduction

2002
Cyclic GMP mediates influence of macula densa nitric oxide over tubuloglomerular feedback.
    Kidney & blood pressure research, 2003, Volume: 26, Issue:1

    Topics: Animals; Citrulline; Cyclic GMP; Enzyme Inhibitors; Feedback, Physiological; Glomerular Filtration Rate; Guanylate Cyclase; Juxtaglomerular Apparatus; Male; Nephrons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Thiourea

2003
Aspirin protects endothelial cells from oxidant damage via the nitric oxide-cGMP pathway.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Aug-01, Volume: 23, Issue:8

    Topics: Animals; Aspirin; Cattle; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Cyclic N-Oxides; Cytoprotection; Diclofenac; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Hydrogen Peroxide; Imidazoles; Indomethacin; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Swine

2003
Inhibitors of nitric oxide synthase block carbon monoxide-induced increases in cGMP in retina.
    Brain research, 2003, Oct-24, Volume: 988, Issue:1-2

    Topics: Animals; Carbon Monoxide; Citrulline; Cyclic GMP; Enzyme Inhibitors; Immunohistochemistry; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Retina; Thiourea; Turtles

2003
NO inhibition of the magnocellular neuroendocrine system in rats is independent of cGMP signaling pathway.
    Experimental neurology, 2003, Volume: 184, Issue:2

    Topics: Animals; Citrulline; Consciousness; Cyclic GMP; Dehydration; Enzyme Inhibitors; Guanylate Cyclase; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Isotonic Solutions; Male; Microdialysis; Nitric Oxide; Nitric Oxide Synthase; Oxytocin; Pituitary Gland, Posterior; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Signal Transduction; Sodium Chloride; Supraoptic Nucleus; Vasopressins; Water-Electrolyte Balance

2003
Upregulation of endothelial nitric oxide synthase in rat aorta after ingestion of fish oil-rich diet.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:2

    Topics: Animals; Aorta; Arginine; Citrulline; Cyclic GMP; Dietary Fats, Unsaturated; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Fish Oils; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidoreductases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxides; Up-Regulation

2004
Biochemical responses of healthy subjects during dietary supplementation with L-arginine.
    The Journal of nutritional biochemistry, 2004, Volume: 15, Issue:9

    Topics: Arginine; Biological Availability; Blood; Blood Glucose; Citrulline; Cyclic GMP; Dietary Supplements; Dose-Response Relationship, Drug; Female; Glycine; Humans; Insulin; Lysine; Male; Ornithine

2004
Co-expression and modulation of neuronal and endothelial nitric oxide synthase in human endothelial cells.
    Journal of molecular and cellular cardiology, 2004, Volume: 37, Issue:5

    Topics: Calcium; Citrulline; Cyclic GMP; Cytosol; Down-Regulation; Endothelium, Vascular; Humans; Imidazoles; Interferon-gamma; Lipopolysaccharides; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Tumor Necrosis Factor-alpha; Umbilical Cord

2004
Nitric oxide stimulates gamma-aminobutyric acid release and inhibits glycine release in retina.
    The Journal of comparative neurology, 2005, Mar-14, Volume: 483, Issue:3

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cadmium; Citrulline; Cyclic GMP; DEET; Dizocilpine Maleate; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Immunohistochemistry; In Vitro Techniques; Molsidomine; Neural Inhibition; Nipecotic Acids; Nitric Oxide; Potassium; Retina; Silver Staining; Thiourea; Turtles; Vigabatrin

2005
Alpha-Tocopherol and endothelial nitric oxide synthesis.
    Annals of the New York Academy of Sciences, 2004, Volume: 1031

    Topics: alpha-Tocopherol; Biopterins; Cells, Cultured; Citrulline; Cyclic GMP; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Serine; Umbilical Veins

2004
Calcium/calmodulin-dependent nitric oxide synthase activity in the CNS of Aplysia californica: biochemical characterization and link to cGMP pathways.
    Journal of inorganic biochemistry, 2005, Volume: 99, Issue:4

    Topics: Animals; Aplysia; Calcium; Calmodulin; Central Nervous System; Citrulline; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Molecular Weight; NADP; Nitric Oxide Donors; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Protein Isoforms; Rats

2005
Regulation of platelet guanylyl cyclase by collagen: evidence that Glycoprotein VI mediates platelet nitric oxide synthesis in response to collagen.
    Thrombosis and haemostasis, 2005, Volume: 94, Issue:2

    Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Citrulline; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Fibrinogen; Guanylate Cyclase; Humans; Immunoblotting; Immunoprecipitation; Nitric Oxide; Nitric Oxide Synthase; Peptides; Phosphatidylinositol 3-Kinases; Platelet Activation; Platelet Membrane Glycoproteins; Protein Kinase C; Signal Transduction; src-Family Kinases; Thromboxane A2

2005
l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Sep-20, Volume: 102, Issue:38

    Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Arteriosclerosis; Ascorbic Acid; Citrulline; Cyclic AMP Response Element-Binding Protein; Cyclic GMP; Diet, Atherogenic; DNA-Binding Proteins; Endothelium, Vascular; ets-Domain Protein Elk-1; Humans; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Proto-Oncogene Proteins; Rabbits; Superoxides; Transcription Factors; Vasodilation; Vitamin E

2005
Citrulline, Viagra and BiDil--bad medicine.
    Alternative medicine review : a journal of clinical therapeutic, 2005, Volume: 10, Issue:4

    Topics: Adult; Arginine; Chronic Disease; Citrulline; Cyclic GMP; Endothelium, Vascular; Erectile Dysfunction; Humans; Hypertension, Pulmonary; Infant; Male; Marketing; Nitric Oxide; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasodilator Agents

2005
Conditional neuronal nitric oxide synthase overexpression impairs myocardial contractility.
    Circulation research, 2007, Feb-16, Volume: 100, Issue:3

    Topics: Animals; Arginine; Caffeine; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cell Size; Cells, Cultured; Citrulline; Cyclic GMP; Doxycycline; Enzyme Induction; Ion Channel Gating; Mice; Mice, Transgenic; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide Synthase Type I; Ornithine; Protein Interaction Mapping; Recombinant Fusion Proteins; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stroke Volume; Ultrasonography; Ventricular Dysfunction, Left

2007
Effect of ocular hypertension on retinal nitridergic pathway activity.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:5

    Topics: Amino Acid Transport Systems, Basic; Animals; Anterior Chamber; Arginine; Blotting, Western; Citrulline; Cyclic GMP; Disease Models, Animal; Hyaluronic Acid; Intraocular Pressure; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ocular Hypertension; Radioimmunoassay; Rats; Rats, Wistar; Retina; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2007
Increase in brain tumor permeability in glioma-bearing rats with nitric oxide donors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Jun-15, Volume: 14, Issue:12

    Topics: Administration, Oral; Animals; Arginine; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Citrulline; Cyclic GMP; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Synergism; Female; Glioma; Hydroxyurea; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Rats; Rats, Inbred F344; Tumor Cells, Cultured

2008
Suppression of grasshopper sound production by nitric oxide-releasing neurons of the central complex.
    Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2008, Volume: 194, Issue:8

    Topics: Acoustic Stimulation; Animal Communication; Animals; Auditory Threshold; Behavior, Animal; Brain; Citrulline; Cyclic GMP; Enzyme Inhibitors; Female; Ganglia, Invertebrate; Grasshoppers; Guanidines; Immunohistochemistry; Nitrergic Neurons; Nitric Oxide; Nitric Oxide Synthase; Sexual Behavior, Animal

2008
Homocysteine decreases platelet NO level via protein kinase C activation.
    Nitric oxide : biology and chemistry, 2009, Volume: 20, Issue:2

    Topics: Analysis of Variance; Blood Platelets; Citrulline; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Homocysteine; Humans; Microscopy, Fluorescence; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Protein Kinase C; Superoxides; Tyrosine

2009
Effect of uncoupling endothelial nitric oxide synthase on calcium homeostasis in aged porcine endothelial cells.
    Cardiovascular research, 2009, Apr-01, Volume: 82, Issue:1

    Topics: Animals; Arginine; Biopterins; Bradykinin; Calcium; Cells, Cultured; Cellular Senescence; Citrulline; Cyclic GMP; Endothelial Cells; Enzyme Inhibitors; Homeostasis; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Superoxides; Swine; Time Factors

2009
NO/cGMP signalling: L: -citrulline and cGMP immunostaining in the central complex of the desert locust Schistocerca gregaria.
    Cell and tissue research, 2009, Volume: 337, Issue:2

    Topics: Animals; Citrulline; Cyclic GMP; Female; Grasshoppers; Immunohistochemistry; Male; Neurons; Nitric Oxide; Signal Transduction

2009
Metabotropic glutamate receptor 5, but not 1, modulates NMDA receptor-mediated activation of neuronal nitric oxide synthase.
    Neurochemistry international, 2010, Volume: 56, Issue:4

    Topics: Animals; Arginine; Blotting, Western; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic AMP; Cyclic GMP; Enzyme Activation; Excitatory Amino Acid Agonists; Guanylate Cyclase; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Oncogene Protein v-akt; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate

2010
Activation of endothelial nitric oxide synthase by the pro-apoptotic drug embelin: Striking discrepancy between nitric oxide-mediated cyclic GMP accumulation and L-citrulline formation.
    Nitric oxide : biology and chemistry, 2010, May-15, Volume: 22, Issue:4

    Topics: Animals; Apoptosis; Benzoquinones; Citrulline; Cyclic GMP; Endothelial Cells; Nitric Oxide; Nitric Oxide Synthase Type III; Signal Transduction

2010
Development of nitrergic neurons in the nervous system of the locust embryo.
    The Journal of comparative neurology, 2010, Apr-15, Volume: 518, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Citrulline; Cyclic GMP; Embryo, Nonmammalian; Enzyme Activators; Ganglia, Invertebrate; Indazoles; Locusta migratoria; NADPH Dehydrogenase; Nerve Regeneration; Nervous System; Neurites; Neurons; Neuropil; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Signal Transduction

2010
Pharmacological modulators of nitric oxide signaling and contextual fear conditioning in mice.
    Psychopharmacology, 2010, Volume: 210, Issue:1

    Topics: Animals; Citrulline; Conditioning, Psychological; Cyclic GMP; Fear; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Signal Transduction; Thiourea

2010
The anandamide effect on NO/cGMP pathway in human platelets.
    Journal of cellular biochemistry, 2011, Volume: 112, Issue:3

    Topics: Arachidonic Acids; Blood Platelets; Calcium; Citrulline; Cyclic GMP; Endocannabinoids; Enzyme Assays; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Platelet Aggregation; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-akt; Signal Transduction

2011
Neurochemical architecture of the central complex related to its function in the control of grasshopper acoustic communication.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Acoustics; Animal Communication; Animals; Citrulline; Cyclic GMP; Female; gamma-Aminobutyric Acid; Gene Expression Regulation; Grasshoppers; Male; Mesencephalon; Neuropil; Nitric Oxide; Receptors, Muscarinic; Signal Transduction

2011
Differential effects of chronic hyperammonemia on modulation of the glutamate-nitric oxide-cGMP pathway by metabotropic glutamate receptor 5 and low and high affinity AMPA receptors in cerebellum in vivo.
    Neurochemistry international, 2012, Volume: 61, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blotting, Western; Chronic Disease; Citrulline; Cyclic GMP; Glutamic Acid; Hyperammonemia; Male; Nitric Oxide; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate

2012
Hyperammonemia alters the modulation by different neurosteroids of the glutamate-nitric oxide-cyclic GMP pathway through NMDA- GABAA - or sigma receptors in cerebellum in vivo.
    Journal of neurochemistry, 2013, Volume: 125, Issue:1

    Topics: Animals; Cerebellum; Citrulline; Cyclic GMP; Extracellular Space; Glutamic Acid; Hyperammonemia; Male; N-Methylaspartate; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, sigma

2013
Oral supplementation with a combination of L-citrulline and L-arginine rapidly increases plasma L-arginine concentration and enhances NO bioavailability.
    Biochemical and biophysical research communications, 2014, Nov-07, Volume: 454, Issue:1

    Topics: Administration, Oral; Animals; Arginine; Atherosclerosis; Biological Availability; Citrulline; Cyclic GMP; Dietary Supplements; Drug Synergism; Humans; Male; Nitric Oxide; Rabbits; Rats; Rats, Sprague-Dawley; Signal Transduction

2014
Effects of hyperbaric oxygen on nitric oxide generation in humans.
    Nitric oxide : biology and chemistry, 2015, Jan-30, Volume: 44

    Topics: Adult; Arginine; Breath Tests; Citrulline; Cyclic GMP; Humans; Hyperbaric Oxygenation; Nitrates; Nitric Oxide; Nitrites; Oxygen; Saliva; Tongue; Young Adult

2015
L-citrulline for protection of endothelial function from ADMA-induced injury in porcine coronary artery.
    Scientific reports, 2015, Jun-05, Volume: 5

    Topics: Animals; Arginine; Cardiovascular Agents; Citrulline; Coronary Vessels; Cyclic GMP; Drug Evaluation, Preclinical; Endothelium, Vascular; Nitric Oxide Synthase Type III; Phosphorylation; Protein Processing, Post-Translational; Superoxides; Sus scrofa; Vascular System Injuries

2015
l-Citrulline ameliorates cerebral blood flow during cortical spreading depression in rats: Involvement of nitric oxide- and prostanoids-mediated pathway.
    Journal of pharmacological sciences, 2017, Volume: 133, Issue:3

    Topics: Animals; Cerebrovascular Circulation; Citrulline; Cortical Spreading Depression; Cyclic GMP; Male; Nitric Oxide; Prostaglandins; Rats, Sprague-Dawley

2017
Effect of ginger, Paullinia cupana, muira puama and l- citrulline, singly or in combination, on modulation of the inducible nitric oxide- NO-cGMP pathway in rat penile smooth muscle cells.
    Nitric oxide : biology and chemistry, 2018, 06-01, Volume: 76

    Topics: Animals; Apoptosis; Cells, Cultured; Citrulline; Cyclic GMP; Male; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Synthase Type II; Olacaceae; Paullinia; Penis; Rats; Rats, Sprague-Dawley; Zingiber officinale

2018
Exogenous l-ARGININE does not stimulate production OF NO or cGMP within the rat corporal smooth muscle cells in culture.
    Nitric oxide : biology and chemistry, 2019, 08-01, Volume: 89

    Topics: Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Male; Muscle, Smooth; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Penis; Phosphodiesterase 5 Inhibitors; Rats, Sprague-Dawley

2019