citrulline has been researched along with arginine in 1640 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 387 (23.60) | 18.7374 |
| 1990's | 414 (25.24) | 18.2507 |
| 2000's | 366 (22.32) | 29.6817 |
| 2010's | 350 (21.34) | 24.3611 |
| 2020's | 123 (7.50) | 2.80 |
| Authors | Studies |
|---|---|
| Detering, C; Varani, G | 1 |
| Townsend, R | 1 |
| Abdelal, AT; Kennedy, EH; Nainan, O | 1 |
| Elsen, A | 1 |
| Van Camp, K; van Sande, M | 1 |
| Batshaw, M; Brusilow, SW; Valle, DL | 1 |
| Allen, MM; Chee, HL; Weathers, PJ | 1 |
| Catlin, BW; Shinners, EN | 1 |
| Bowman, BJ; Davis, RH; Karlin, JN | 1 |
| Kamikawa, EM; Morris, JG; Rogers, QR; Winterrowd, DL | 1 |
| Lee, SH; Rozee, KR | 1 |
| Garnett, HM | 1 |
| Sperry, JF; Wilkins, TD | 1 |
| Chibata, I; Tosa, T | 1 |
| Chibata, I; Kato, J; Kisumi, M; Takagi, T | 1 |
| Chakrabarty, S; Duerre, JA | 1 |
| Simon, JP; Stalon, V | 1 |
| Grof, J; Jambor, E; Molnár, J; Papp, G | 1 |
| Hensgens, HE; Meijer, AJ | 1 |
| Bergström, J; Eriksson, S; Fürst, P; Hellström, K; Möller, P | 1 |
| Ha, YH; Milner, JA | 1 |
| Camargo, EP; Coelho, JA; Figueiredo, EN; Moraes, G | 1 |
| Irr, JD; Jacoby, LB | 1 |
| Jacoby, LB | 2 |
| Cooper, AJ; Meister, A | 1 |
| Kopple, JD; Schutz, I; Swendseid, ME; Wang, M | 1 |
| Kawamura, M | 1 |
| Epstein, M; Loutzenhiser, R; Perez, GO; Rietberg, B | 1 |
| Camargo, EP; Yoshida, N | 1 |
| Gopalakrishna, R; Nagarajan, B | 2 |
| Bowman, BJ; Davis, RH; Weiss, RL | 1 |
| Charlier, J; Gerlo, E | 1 |
| Amil, MR; Fernández, J; Mataix, FJ | 1 |
| Batshaw, M; Brusilow, S; Kulovich, S; Nyhan, W; Spector, E; Thoene, J; Walser, M | 1 |
| Craigie, JS; Laycock, MV | 1 |
| Assan, R; Attali, JR; Ballerio, G; Boillot, J; Girard, JR | 1 |
| Gróf, J; Menyhárt, J | 1 |
| Batshaw, M; Brusilow, S; Robinson, B; Sherwood, G; Walser, M | 1 |
| Nakao, T; Oyanagi, K; Sogawa, H | 1 |
| Eberl, R; Partsch, G | 1 |
| Rogers, GE; Taylor, LD | 1 |
| Hansen, S; MacLean, J; Perry, TL | 1 |
| Blakemore, RP; Canale-Parola, E | 1 |
| Nakao, T; Orii, T; Oyanagi, K; Sato, S; Sogawa, H | 1 |
| Clara, R; Mardens, Y; Strauven, T; Terheggen, H | 1 |
| Dawson, L; Kohrman, AF; Wilson, RW | 1 |
| Boyen, A; Charlier, D; Crabeel, M; Cunin, R; Glansdorff, N; Piérard, A | 1 |
| Chan, W; Kopple, JD; Swendseid, ME; Wang, M | 2 |
| Ratner, S | 2 |
| Noda, K | 1 |
| Milner, JA; Visek, WJ | 1 |
| Briggs, S; Freedland, RA | 1 |
| Bloom, AD; Lockridge, O; Spector, EB | 1 |
| Awrich, AE; Cantrell, JE; Patterson, JH; Rudman, D; Stackhouse, WJ | 1 |
| Clark, JH; Davis, CL; Derrig, RG; Spires, HR | 1 |
| Ignarro, LJ; Rogers, NE | 1 |
| Bult, H; Herman, AG; Jorens, PG; van Overveld, FJ; Vermeire, PA | 1 |
| Hishikawa, K; Kato, R; Nakaki, T; Saruta, T; Suzuki, H | 1 |
| Shiro, Y; Yabuki, S | 1 |
| Ramwell, PW; Thomas, G | 1 |
| Cottenceau, G; Dherbomez, M; Lettellier, F; Lubochinsky, B | 1 |
| Costa, E; Kiedrowski, L; Wroblewski, JT | 2 |
| Böhme, E; Heinzel, B; John, M; Klatt, P; Mayer, B | 1 |
| Bassetti, S; Keist, R; Keller, R; Klauser, S; Mülsch, A | 1 |
| Bush, PA; Gonzalez, NE; Griscavage, JM; Ignarro, LJ | 1 |
| Bush, PA; Gonzalez, NE; Ignarro, LJ | 1 |
| Datto, GA; Wolff, DJ | 1 |
| Marletta, MA; White, KA | 1 |
| Brenner, BM; Collins, T; Lamas, S; Marsden, PA; Michel, T | 1 |
| Flaman, JM; Henry, Y; Lepoivre, M | 1 |
| Shimizu, H | 1 |
| Chaudhuri, G; Fukuto, JM; Hayashi, T; Ignarro, LJ | 1 |
| Boucher, JL; Delaforge, M; Genet, A; Henry, Y; Mansuy, D; Vadon, S | 1 |
| Brosnan, JT; Brosnan, ME; Dhanakoti, SN; Herzberg, GR | 2 |
| Boucher, JL; Delaforge, M; Genet, A; Mansuy, D; Vadon, S | 1 |
| Johnson, EA; Patterson-Curtis, SI | 1 |
| Bredt, DS; Dawson, TM; Dawson, VL; London, ED; Snyder, SH | 1 |
| Brenner, BM; Lamas, S; Marsden, PA; Michel, T | 1 |
| Chen, PY; Sanders, PW | 2 |
| Gilker, C; Griffith, OW; Kwon, NS; Matthews, DE; Nathan, CF; Stuehr, DJ | 1 |
| Blachier, F; Gomis, R; Malaisse, WJ; Mourtada, A; Sener, A | 1 |
| McLaurin, J; Moscarello, MA | 1 |
| Böhme, E; Heinzel, B; John, M; Mayer, B; Schultz, G; Wachter, H; Werner, ER | 1 |
| Förstermann, U; Mitchell, JA; Murad, F; Sheng, H | 1 |
| Brosnan, JT; Wu, GY | 1 |
| Gekle, M; Silbernagl, S | 1 |
| Hommes, FA; Koch, R; Pandya, AL; Williams, JC | 1 |
| Azuma, T; Higa, S; Kishimoto, S; Sakoda, S; Suzuki, T; Tsujino, S | 1 |
| Legrain, C; Stalon, V; Tricot, C | 1 |
| Bardet, J; Kamoun, P; Parvy, P; Rabier, D | 1 |
| Gross, KL; Hartman, WJ; Meydani, SN; Prior, RL; Ronnenberg, AG | 1 |
| Benninghoff, B; Dröge, W; Lehmann, V | 1 |
| Rogers, QR; Spensley, MS; Willits, NH; Zicker, SC | 1 |
| Benninghoff, B; Dröge, W; Eck, HP; Lehmann, V | 1 |
| Piña, E; Saavedra-Molina, A | 1 |
| Frölich, JC; Haake, G; Kastner, S; Klanke, B; Radermacher, J; Schurek, HJ; Stolte, HF | 1 |
| Hecker, M; Mitchell, JA; Sessa, WC; Vane, JR | 1 |
| Mori, M; Murakami, T; Noda, T; Saheki, T; Shimada, T; Takiguchi, M; Tashiro, M; Yamamura, K | 1 |
| Chenais, B; Lepoivre, M; Tenu, JP; Yapo, A | 1 |
| Blachier, F; Darcy-Vrillon, B; Duée, PH; Malaisse, WJ; Sener, A | 1 |
| Blachier, F; Darcy-Vrillon, B; Duee, PH; M'Rabet-Touil, H; Posho, L | 2 |
| Aaron, DK; Boling, JA; Davenport, GM; Schillo, KK | 1 |
| Azuma, I; Kimura, T; Kobayashi, S; Ohno, T; Sugimura, K; Wada, Y | 1 |
| Billiar, TR; Curran, RD; Hoffman, RA; Langrehr, JM; Simmons, RL | 1 |
| Hibbs, JB; Lancaster, JR | 1 |
| Anggård, EE; Harris, HJ; Hecker, M; Sessa, WC; Vane, JR | 1 |
| Floderus, E; Linder, LE; Sund, ML | 1 |
| Bankir, L; Hus-Citharel, A; Levillain, O; Morel, F | 1 |
| Atkinson, DE; Brady, JF; Morimoto, BH | 1 |
| Baeblich, SE; Böhme, E; Klein, MM; Schmidt, HH; Zernikow, BC | 1 |
| Adams, LB; Hibbs, JB; Krahenbuhl, JL; Taintor, RR | 1 |
| Harris, HJ; Hecker, M; Katsura, M; Mitchell, JA; Thiemermann, C; Vane, JR | 1 |
| Albina, JE; Caldwell, MD; Henry, WL; Mills, CD | 1 |
| Eichler, W | 1 |
| Rad-niknam, M; Sharples, D | 1 |
| Gale, DS; Iafolla, AK; Roe, CR | 1 |
| Nagata, S; Senshu, T | 1 |
| Hayakawa, C; Kato, T; Mizutani, N; Sano, M | 2 |
| Kato, T; Mizutani, N; Sano, M | 1 |
| Boudbid, H; Lepoivre, M; Petit, JF | 1 |
| Bey, P; Mehdi, S; Skoog, MT; Wiseman, JS | 1 |
| Dillon, JR; Picard, FJ | 1 |
| Knowles, RG; Moncada, S; Palacios, M; Palmer, RM | 1 |
| Bredt, DS; Snyder, SH | 1 |
| Ambani, LM; Apte, BN; Balsekar, MV; Bhatia, RS; Shah, SB | 1 |
| Marletta, MA; Tayeh, MA | 1 |
| Billiar, TR; Curran, RD; Hofmann, K; Simmons, RL; West, MA | 1 |
| Bartel, DP; Green, R; Hanna, M; Michel, F; Szostak, JW | 1 |
| Bachmann, C; Baerlocher, K; Hochreutener, H; Issakainen, J | 1 |
| Billiar, TR; Curran, RD; Ferrari, FK; Simmons, RL; Stuehr, DJ | 1 |
| Alonso, E; Rubio, V | 1 |
| Ben-Yoseph, Y; Mitchell, DA | 1 |
| Iyengar, R; Marletta, MA; Stuehr, DJ | 1 |
| Dy, M; Kamoun, PP; Schneider, E | 1 |
| Anderson, PM; Casey, CA | 1 |
| Moncada, S; Palmer, RM | 1 |
| Bentz, BG; Billiar, TR; Curran, RD; Simmons, RL; Stuehr, DJ; West, MA | 1 |
| Davis, RH; Ristow, JL | 2 |
| Zieve, L | 1 |
| Shibata, K; Watanabe, T | 1 |
| Bachmann, C; Colombo, JP; Dionisi Vici, C; Gambarara, M; Sabetta, G | 1 |
| Driessen, AJ; Konings, WN; Poolman, B | 1 |
| Girgis, N; Herrin, J; McGravey, V; Shah, BL; Shih, VE | 1 |
| Legrain, C; Momin, P; Stalon, V; Vander Wauven, C | 1 |
| Ashton, DS; Moncada, S; Palmer, RM | 1 |
| Aida, M; Matsoo, M; Matsuo, T; Nakamura, H; Takemine, H | 1 |
| Amber, IJ; Hibbs, JB; Taintor, RR; Vavrin, Z | 1 |
| Albina, JE; Barbul, A; Caldwell, MD; Henry, WL; Mastrofrancesco, B; Mills, CD; Thirkill, CE | 1 |
| Kagamimori, S; Naruse, Y; Nishino, H; Shiroishi, K; Watanabe, M | 1 |
| Daniel, RM; Monk, CR; Morgan, HW; Patchett, ML | 1 |
| Malina, H; Robert-Gero, M | 1 |
| Akiyoshi, H; Ichihara, K; Inoue, I; Ishii, S; Mito, T; Nakajima, M; Saheki, T; Takakura, H; Takashima, S; Takeshita, K | 1 |
| Champomier, MC; Montel, MC | 1 |
| Hagihara, S; Inoue, I; Kobayashi, K; Matuo, S; Noda, T; Saheki, T | 1 |
| Hagihara, S; Ichiki, H; Imamura, Y; Inoue, I; Kobayashi, K; Matuo, S; Noda, T; Saheki, T; Tatsuno, M | 1 |
| Pardo, JP; Piña, E; Saavedra-Molina, A; Villalobos-Molina, R | 1 |
| Bitonti, AJ; Byers, TJ; Kim, BG; McCann, PP; Sobota, A | 1 |
| Baker, DH; Edmonds, MS; Lowry, KR | 1 |
| Hara, S; Ikenaka, T; Kurokawa, T; Sugawara, K; Takahara, H | 1 |
| Kimoto, M; Ogawa, T; Sasaoka, K | 1 |
| Maltby, DA; Millington, DS; Roe, CR | 1 |
| Hurwitz, R; Kretchmer, N | 1 |
| Kawashima, H | 1 |
| Freedland, RA; Meijer, AJ; Tager, JM | 1 |
| Anast, CS; Carpenter, TO; Holtrop, ME; Levy, HL; Shih, VE | 1 |
| Brusilow, SW; Farmer, ER; Goldblum, OM; Maldonado, YA | 1 |
| Rogers, QR; Visek, WJ | 1 |
| Morris, JG | 1 |
| Aoyama, T; Kimura, H; Norimura, T; Tsuchiya, T | 1 |
| Alewood, P; Elmer, H; Hoogenraad, N; Johns, RB; Totino, N; Wraight, C | 1 |
| Veĭnblat, VI | 1 |
| Peeters, G; Roets, E; Verbeke, R | 1 |
| Piérard, A; Ramos, F; Stalon, V; Wiame, JM | 1 |
| Cabet, D | 1 |
| Gai, V; Gastaldi, L; Nattero, G | 1 |
| Bazzicalupo, G; Pietranera, P | 1 |
| Drago, U; Finotto, E; Ongaro, G | 2 |
| Avanzi, G; Meneghini, P | 1 |
| Rizzo, F | 1 |
| Catalfamo, G; Melotti, G; Soffritti, E | 1 |
| Merlini, R; Rossini, A | 1 |
| Ivaldi, A | 1 |
| Miracco, A; Orlando, V | 1 |
| Di Lorenzo, S | 1 |
| Nicoletti, A; Piro, E; Ruffolo, S | 1 |
| Floris, E; Mura, B | 1 |
| Mora, J; Salceda, R; Sanchez, S | 1 |
| Martinez, L; Mora, J; Sanchez, S | 1 |
| Cooke, BC; Williamson, JD | 2 |
| Barthelmess, IB; Curtis, CF; Kacser, H | 1 |
| Mekhedov, LN | 1 |
| Blagoveshchenskiĭ, VA; Borishpolets, ZI; Dolgikh, MS | 1 |
| Campbell, JW; Tramell, PR | 2 |
| Consigli, RA; Rogers, QR; Winters, AL | 1 |
| Hoet, PP; Wiame, JM | 1 |
| Hsia, YE | 1 |
| Cybis, JJ; Davis, RH | 1 |
| Dürr, M; Wiemken, A | 1 |
| Hiort, U; Kating, H | 1 |
| Mokkerjee, A; Palit, R; Podder, NG; Saha, NN | 1 |
| Scott-Emuakpor, AB | 1 |
| Levin, B; Oberholzer, VG; Palmer, T | 2 |
| Cathelineau, L; Charpentier, C; Polonovski, C; Saudubray, JM | 1 |
| Renfree, MB | 1 |
| Brenton, DP; Cusworth, DC; Hartley, S; Kuzemko, JA; Lumley, S | 1 |
| Asafov, GB; Ekisenina, NI; Ivanova, LM; Lumel'skiĭ, VIa; Smagin, VG | 1 |
| Goodman, SI; Hill, HZ | 1 |
| Ottow, JC | 1 |
| Chibata, I; Sato, T; Tosa, T; Yamamoto, K | 1 |
| Massart-Leën, AM; Peeters, G; Roets, E; Verbeke, R | 1 |
| Burton, AF; Storr, JM | 1 |
| Campbell, JW; Drotman, RB | 2 |
| Cohen, PP; Reddy, MK; Wixom, RL | 1 |
| Bollon, AP; Vogel, HJ | 1 |
| McGinnis, E; Williams, AL; Williams, LS; Yem, DW | 1 |
| Eddy, AA; Inkson, C; Seaston, A | 1 |
| Bagchee, SN; Guha, A; Panchal, CJ | 1 |
| Berg, CM; Rossi, JJ | 1 |
| Frimpter, GW | 1 |
| Causa, P; Perri, GC | 1 |
| Coulson, RA; Herbert, JD | 1 |
| Andrews, TR; Reid, RG | 1 |
| Balinsky, JB; Dicker, SE; Elliott, AB | 1 |
| Nordmann, J; Nordmann, R; Petit, MA | 1 |
| Featherston, WR; Freedland, RA; Rogers, QR | 1 |
| Fifkova, E; Van Harreveld, A | 1 |
| Horne, FR | 1 |
| Berger, M; Schwarz, E | 1 |
| Davis, RH; Subramanian, KN; Weiss, RL | 1 |
| Fischer, B; Keller-Schierlein, W; Kneifel, H; König, WA; Loeffler, W; Müller, A; Muntwyler, R; Zähner, H | 2 |
| Deetjen, P; Silbernagl, S | 1 |
| Herbert, JD | 1 |
| Teijema, HL; van Gelderen, HH | 1 |
| Ottow, JC; Zolg, W | 1 |
| Tulemisova, KA | 1 |
| Romano, N; Scarlata, G | 1 |
| Bergman, EN; Kaufman, CF; Williams, HH; Wolff, JE | 1 |
| De la Llosa, P; Durosay, M; Jutisz, M; Tertrin-Clary, C | 1 |
| Fell, V; Pollitt, RJ; Sampson, GA; Wright, T | 1 |
| Bergström, J; Fürst, P; Norée, LO; Vinnars, E | 1 |
| Buist, NR; Hepburn, CA; Kennaway, NG; Ramberg, DA; Strandholm, JJ | 1 |
| Burgess, EA; Butler, LJ; Levin, B; Oberholzer, VG; Palmer, T | 1 |
| Danks, DM; Tippett, P; Zentner, G | 1 |
| Crane, CW; Jenner, FA; Pollitt, RJ | 1 |
| Hahn, RG; Kenny, GE | 1 |
| Koffron, KL; Morris, DR | 1 |
| Prozesky, OW | 1 |
| Menne, F | 1 |
| Holden, JT; Wilson, OH | 1 |
| Haţegan, D | 1 |
| Tabor, CW; Tabor, H | 1 |
| Colombo, JP | 1 |
| Williams, LS; Yem, DW | 1 |
| Levin, B | 1 |
| Auriol, P; Touzé, A | 1 |
| Freed, JJ; Kish, VM; Luongo, L; Sorof, S; Young, EM | 1 |
| Cahill, CF; Felig, P; Marliss, E; Ohman, JL | 1 |
| Franks, NE | 1 |
| Cole, RD; Matthews, KS | 1 |
| Shih, VE | 1 |
| Drotman, RB; Freedland, RA | 1 |
| Jacoby, LB; Littlefield, JW; Milunsky, A; Shih, VE; Wilroy, RS | 1 |
| Cherry, WB; Lambert, MA; Moss, CW | 1 |
| Barrio, A; Carlisky, NJ | 1 |
| Freedland, RA; Rogers, QR; Symmons, RA | 1 |
| Gerok, W; Haag, G; Holldorf, AW | 1 |
| Davis, RH | 3 |
| Mirvish, SS | 1 |
| Campbell, DJ; Reid, DW; Yakymyshyn, LY | 1 |
| Seydoux, F; Yon, J | 1 |
| Hornig, D; Weber, F; Wiss, O | 1 |
| Blazevic, DJ; Ederer, GM; Williams, GA | 1 |
| Chibata, I; Kakimoto, T; Nishimura, N; Shibatani, T | 1 |
| Berry, HK | 1 |
| Geisler, C; Höcker, P; Stacher, A; Wiser, M | 1 |
| Chu, P; Miller, AL | 1 |
| Grabarek-Braeczyk, J; Kleczkowski, K; Reifer, L | 1 |
| Jones, ME; Prescott, LM | 1 |
| Carton, D; De Schrijver, F; Hooft, C; Kint, J; Van Durme, J | 1 |
| Accardo, G; Mirizio, A; Ruberti, A | 1 |
| Meyer, ME | 2 |
| Crokaert, R; Wisenfeld, M | 1 |
| Dietz, RW; Flipse, RJ | 1 |
| Mille, T; Pastorino, G | 1 |
| Bechet, J; Ramos, F; Thuriaux, P; Wiame, JM | 1 |
| Kauffman, NJ; Moore, RB | 1 |
| Huitrón, C; Palacios, R; Soberón, G | 1 |
| Gordon, WG; Hipp, NJ; Pepper, L | 1 |
| Fishman, W; Sie, HG | 1 |
| Miller, DL; Rodwell, VW | 1 |
| Ogata, K; Yorifuji, T | 1 |
| Anfinsen, CB; Chaiken, IM | 1 |
| Cañedo, L; Martuscelli, J; Mora, J | 1 |
| Ortíz-Pineda, J; Soberón, G; Tarrab, R | 1 |
| Kekomäki, M | 1 |
| Barness, LA; Morrow, G | 1 |
| Frahn, JL; Mills, JA | 1 |
| Berger, R; Broyer, M | 1 |
| Hein, GE; Sanborn, BM | 2 |
| Palacios, R; Soberón, G; Tarrab, R | 1 |
| Grabarek-Bralczyk, J; Kleczkowski, K | 1 |
| Robinson, JW | 1 |
| Rickert, WS; Viswanatha, T | 1 |
| Moulder, JW; Treuhaft, MW | 1 |
| Bernlohr, RW; Laishley, EJ | 1 |
| Charbonneau, R; Roberge, A | 3 |
| Atlavin, AB; Koval'skiĭ, VV; Lekarev, VS; Lutskiĭ, DIa | 1 |
| Nordmann, R | 1 |
| Cossins, EA; Shargool, PD | 1 |
| Landau, RL; Lugibihl, K | 2 |
| Bayer, SM; McMurray, WC | 1 |
| Charles, R; De Haan, EJ; Hoek, JB; Tager, JM | 1 |
| Ahmad, F; Alexander, JK; Barnes, IJ; Moat, AG | 1 |
| Horie, Y; Inokuchi, T; Ito, T | 1 |
| Dénes, G; Faragó, A | 2 |
| Carton, D; De Schrijver, F; Hooft, C | 1 |
| Strijkert, PJ; Sussenbach, JS | 1 |
| Rock, GC | 1 |
| Durzan, DJ | 1 |
| Dolan, TF; Nelligan, DJ; Shih, VE; Solitare, GB | 1 |
| Coryell, ME; Farrow, RT; Gatz, AJ; Hall, WK; Horton, BF; Looper, JW; Sisson, BD; Thevaos, TG; Welter, DA | 1 |
| Hill, DL; Van Eys, J | 1 |
| Kurelec, B; Rijavec, M | 1 |
| Campbell, JW | 1 |
| Felber, JP; Robinson, JL | 1 |
| Jirgl, V | 1 |
| Dundas, IE; Halvorson, HO | 1 |
| Coetzee, JN; Prozesky, OW | 1 |
| Cousens, K; Davis, JS; Kidder, GW | 1 |
| Herrmann, RL; White, CW | 1 |
| Eckert, L; Kating, H; Lleczkowski, K | 1 |
| Senft, AW | 1 |
| Brown, H; Diamond, R; Efron, ML; Moser, HW; Neumann, CG | 1 |
| Armstrong, MD; Robinow, M | 1 |
| Cohen, W; Petra, PH | 1 |
| Castañeda, M; Martuscelli, J; Mora, J | 1 |
| Barness, LA; Efron, ML; Morrow, G | 1 |
| Nazario, M | 1 |
| Anders, P; Curtius, HC; Hadorn, B; Halverson, R; Hanimann, F | 1 |
| Ong, EB; Woody, NC | 1 |
| Chambers, P; Hill, DL | 1 |
| Fairley, JL; Wampler, DE | 1 |
| Ali, AM | 1 |
| Chesters, PM; Osborn, JG; Williamson, JD | 1 |
| Ishikawa, Y; Kaiser-Kupfer, MI; Kuwabara, T | 1 |
| Crozier, GL; Freedland, RA; Hicks, BL; Meijer, AJ | 1 |
| Busiello, M; Cini, C; De Marco, C; Di Girolamo, M | 1 |
| Perheentupa, J; Rajantie, J; Simell, O | 2 |
| Dy, M; Kamoun, P; Rocchiccioli, F; Schneider, E | 1 |
| Eller, AG; Hommes, FA; Kitchings, L | 1 |
| Behbehani, AW; Gahr, M; Schröter, W | 1 |
| Baumberg, S; Mountain, A | 1 |
| Davidson, JS; Harley, EH | 1 |
| Flint, HJ; Kacser, H; Porteous, DJ | 1 |
| Kohsaka, M; Ochi, K; Saito, Y; Ueda, I; Umehara, K | 1 |
| Cerra, FB; Goodman, MW; Konstantinides, FN; Zieve, L | 1 |
| Bachmann, C | 2 |
| Bullock, MW; Chiu, SH; Fiala, R | 1 |
| Rogers, GE; Rothnagel, JA | 2 |
| Batshaw, ML | 1 |
| Bullock, MW; Fiala, RR; Mowery, PC; Tsou, HR | 1 |
| Beutin, L; Eisen, H | 1 |
| Aoyagi, K; Narita, M; Ohba, S; Tojo, S | 1 |
| Berghuis, M; Cats, BP; de Klerk, JB; Duran, M | 1 |
| Baumgarten, IM; Davidson, JS; Harley, EH | 1 |
| Baker, DH; Czarnecki, GL | 1 |
| Ban, M; Kato, T; Maehara, M; Mizutani, N; Watanabe, K | 1 |
| Ameen, M; Palmer, T | 1 |
| Perheentupa, J; Rajantie, J; Rapola, J; Simell, O | 1 |
| González-Noriega, A; Prieto, E; Velázquez, A; Verduzco, J | 1 |
| Karube, K; Minami, R; Nakao, T; Oyanagi, K; Sogawa, H; Tsugawa, S | 1 |
| Karsai, T; Szabó, G; Vargha, G | 1 |
| Jenness, DD; Schachman, HK | 1 |
| Funahashi, M; Kato, H; Nakagawa, H; Shiosaka, S | 1 |
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| Bendavid, C; Bordeau, V; Cattoir, V; Cogné, M; Coirier, V; Creusat, F; Daniel, Y; Delaloy, C; Dessauge, E; Dessauge, F; Fromenty, B; Gacouin, A; Gauthier, J; Grégoire, M; Lamaison, C; Le Naoures, C; Le Tulzo, Y; Lesouhaitier, M; Michelet, C; Moreau, C; Petitjean, K; Piau, C; Reizine, F; Roussel, M; Tadié, JM; Tarte, K; Thibault, R; Uhel, F; Zmijewski, J | 1 |
| Arnold, CE; Bazer, FW; Bradbery, AN; Fridley, J; He, W; Leatherwood, JL; Martinez, RE; Posey, EA; Silvers, BL; Wu, G | 1 |
| Anand, SS; Atkinson, SA; Azab, S; Britz-McKibbin, P; de Souza, RJ; Desai, D; Gupta, M; Morrison, K; Shanmuganathan, M; Sikorski, C; Teo, K | 1 |
| Abdioglu, M; Benesova, D; Esen, O; Eser, MC; Gabrys, T; Karayigit, R | 1 |
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| Li, S; Lyu, G; Yang, H; Yang, Y | 1 |
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| Li, M; Miao, M; Wang, W; Zhang, T | 1 |
| Alvares, TS; Conte-Junior, CA; Figueroa, A; Oliveira, GV; Volino-Souza, M | 1 |
| Andersson, DC; Carlström, M; Gastaldello, S; Lanner, JT; Lund, LH; Pironti, G; Rassier, DE; Westerblad, H; Yamada, T | 1 |
| Abusoglu, G; Abusoglu, S; H Yerlikaya, F; Kuzu, M; Onmaz, DE; Tezcan, D; Unlu, A; Yilmaz, S | 1 |
| Bouma, GJ; Cherrington, BD; Christensen, AO; DeVore, SB; Edwards, S; Khan, SA; Li, G; Navratil, AM; Rothfuss, HM; Snow, B; Young, CH | 1 |
| Alvares, TS; Conte-Junior, CA; de Oliveira, GV; Volino-Souza, M | 1 |
| Chang, S; Chen, Y; Deng, S; Du, K; Fan, X; Feng, X; Gao, Y; Hou, G; Hu, F; Jin, Z; Liang, J; Luo, X; Meltzer, SJ; Peng, Y; Qin, J; Xiao, S; Xu, Y; Zhang, X | 1 |
| Beckmann, B; Blau, LS; Dimina, L; Finkel, A; Jantz, M; Lützow, M; Maassen, N; Mariotti, F; Röhrig, MA; Shushakov, V; Thorns, A; Tsikas, D | 1 |
| Do, H; Han, SJ; Hwang, J; Lee, CW; Lee, JH; Lee, MJ; Lee, SG; Nguyen, DL; Oh, H | 1 |
| Cao, P; Cao, R; Cao, Y; Chi, C; Hong, M; Huang, B; Jiang, Y; Li, S | 1 |
| Deutz, NEP; Engelen, MPKJ; Ten Have, GAM; Thaden, JJ; Wierzchowska-McNew, RA | 1 |
| Ahmed, F; Coonrod, SA; Demeter, EA; Grenier, JK; Marks, BA; Mittal, C; Mukai, C; Nelissen, S; Sams, KL; Tate, AE | 1 |
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| Dillon, KN; Figueroa, A; Fischer, SM; Kang, Y; Maharaj, A; Martinez, MA | 1 |
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| Tsikas, D | 2 |
| Ibrahim, FM; Nasef, NA; Saad, AE; Zoghroban, HS | 1 |
| Banerjee, A; Cohen, MJ; Cralley, A; D'Alessandro, A; DeBot, M; Dzieciatkowska, M; Erickson, C; Hallas, W; Hansen, KC; Jones, K; LaCroix, I; Mitra, S; Moore, EE; Sauaia, A; Schaid, TR; Silliman, CC; Thielen, O | 1 |
| Doroszko, A; Fortuna, P; Gawryś, J; Martynowicz, H; Mochol, J; Rola, P; Szahidewicz-Krupska, E; Wiśniewski, J | 1 |
| Chen, C; Chen, J; Cui, Q; Deng, J; Huang, B; Li, Y; Liu, J; Liu, S; Lu, S; Lv, J; Ma, J; Tang, K; Wang, D; Yang, Z; Zhang, H | 1 |
| Chen, Y; Wang, G; Wang, Z; Yan, X; Zhang, L; Zhao, F; Zhou, M | 1 |
| Amé, P; Delaloy, C; Desvois, Y; Gauthier, J; Ghukasyan, G; Grégoire, M; Lesouhaitier, M; Moreau, C; Reizine, F; Tadié, JM; Tarte, K | 1 |
| Akiduki, S; Matsumoto, H; Miura, N; Morishita, K; Yasuda, T | 1 |
| Bagheripour, F; Ghasemi, A; Jeddi, S; Kashfi, K | 1 |
| Gonzalez, AM; Hoffman, JR; Pinzone, AG; Townsend, JR | 1 |
| Adachi, T; Hitomi, Y; Ido, Y; Ikegami, Y; Ishinoda, Y; Iwashita, M; Kagami, K; Kawai, A; Masaki, N; Miyazaki, K; Nagatomo, Y; Namba, T; Takase, B; Taruoka, A; Toya, T; Yasuda, R; Yumita, Y | 1 |
| Bessa, H; Bossuyt, X; De Somer, L; Dillemans, L; Gouwy, M; Martens, E; Matthys, P; Metzemaekers, M; Proost, P; Verschueren, P; Wouters, C; Yu, K | 1 |
| Drapała, A; Samborowska, E; Szlęzak, D; Ufnal, M; Wróbel, M | 1 |
| Jung, YP; Kim, AJ; Kim, H; Kim, S; Kim, SW; Lim, K; Park, HY; Seo, J | 1 |
| Fang, ZZ; Li, N; Yang, X; Zhang, J; Zhang, Q; Zhang, W; Zheng, J | 1 |
| Calvani, R; Ciciarello, F; Coelho-Júnior, HJ; Di Mario, C; Galluzzo, V; Gervasoni, J; Gremese, E; Landi, F; Lomuscio, S; Marini, F; Marzetti, E; Paglionico, AM; Picca, A; Santucci, L; Tolusso, B; Tosato, M; Urbani, A | 1 |
| Figueroa, A; Wong, A | 1 |
| Bazer, FW; Burghardt, RC; Johnson, GA; Li, X; Wu, G | 1 |
| Elango, R | 1 |
| Benjamim, CJR; Gonzaga, LA; Porto, AA; Valenti, VE | 1 |
| Cabre, HE; Gould, LM; Greenwalt, CE; Smith-Ryan, AE | 1 |
| Arens, D; Buchholz, T; Cvetkovic, O; Nehrbass, D; Richards, RG; Stoddart, MJ; Tepic, S; Zeiter, S | 1 |
| Au, AYM; Bahadory, F; Endre, ZH; Erlich, J; Guiney, H; Horvath, AR; Mantik, K; Poulton, R; Stathakis, P; Walker, R | 1 |
| Demczko, MM; Ganetzky, RD; He, M; Hong, X; Master, SR; Wongkittichote, P | 1 |
| Bartee, E; Bartee, MY; Curtsinger, HD; Dryja, P | 1 |
| Althoff, MD; Federman, A; Grasemann, H; Holguin, F; Jin, Y; McGrath, M; Peterson, R; Sharma, S; Wisnivesky, JP | 1 |
| Almeida, CC; Baião, DDS; da Silva, DVT; Paschoalin, VMF | 1 |
| Aschenbrandt, G; Ficner, R; Garbers, TB; Herzberg, C; Stülke, J; Warneke, R | 1 |
| Brown, LAS; George, RP; Harris, F; Jo, H; Kelleman, M; Morris, CR; Reyes, LZ; Winterberg, PD | 1 |
| Alcudia, A; González-Ortiz, M; Mosso, C; Ortiz-Cerda, T; Vázquez-Román, V | 1 |
| Arnoux, JB; Benoist, JF; Bérat, CM; Bouchereau, J; Brassier, A; de Lonlay, P; Imbard, A; Josse, C; Montestruc, F; Pontoizeau, C; Schiff, M | 1 |
| Li, Y; Liu, XF; Lu, JJ; Qiang, JW; Yang, XY | 1 |
| Astudillo, M; Balasubramanyam, A; Deen, S; Guffey, D; Hsu, JW; Huang, X; Jahoor, F; Redondo, MJ; Tosur, M; Uysal, S | 1 |
| Gu, Z; Li, L; Li, W; Pei, W; Qian, X; Wu, Q; Zhang, Y; Zhang, Z; Zhu, J | 1 |
| Asfar, P; Bendavid, C; Commereuc, M; Cynober, L; Delclaux, C; Diehl, JL; Gacouin, A; Gey, A; Gregoire, M; Le Pabic, E; Le Tulzo, Y; Lesouhaitier, M; Locher, C; Maamar, A; Moreau, C; Reignier, J; Roussel, M; Tadié, JM; Tarte, K; Tartour, E; Terzi, N; Thibault, R | 1 |
111 review(s) available for citrulline and arginine
| Article | Year |
|---|---|
Transformations of organic compounds by immobilized microbial cells.
Topics: Arginine; Aspartic Acid; Bacteria; Citrulline; Enzymes, Immobilized; Fumarates; Fungi; Histidine; Malates; Microbiological Techniques; Penicillanic Acid; Penicillins; Species Specificity; Stereoisomerism; Urocanic Acid | 1977 |
The urea cycle in uremia.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Aspartic Acid; Citrulline; Humans; Kidney; Liver; Multienzyme Complexes; Muscles; Ornithine; Ornithine Carbamoyltransferase; Urea; Uremia | 1975 |
[A case of ornithine transcarbamylase deficiency presenting severe symptoms in adulthood].
Topics: Adult; Ammonia; Arginine; Citrulline; Consciousness Disorders; Female; Glycine; Humans; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid | 1992 |
Conditional deficiencies of ornithine or arginine.
Topics: Amino Acids; Amino Acids, Branched-Chain; Ammonia; Animals; Arginine; Citrulline; Female; Glycine; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Lysine; Models, Biological; Ornithine; Orotic Acid; Pregnancy; Protein Deficiency; Urease | 1986 |
Nutritional influences on the distribution of the urea cycle: intermediates in isolated hepatocytes.
Topics: Animals; Arginine; Chloroquine; Citrulline; Cytosol; Digitonin; Liver; Mitochondria, Liver; Models, Biological; Urea | 1985 |
The precursors of milk proteins.
Topics: Amino Acids; Animals; Arginine; Biological Transport; Caseins; Cattle; Citrulline; Female; Glucose; Mammary Glands, Animal; Methods; Milk Proteins; Ornithine; Pregnancy; Protein Precursors | 1974 |
Inherited hyperammonemic syndromes.
Topics: Acidosis; Amino Acids; Ammonia; Animals; Arginine; Brain; Brain Diseases; Chemical and Drug Induced Liver Injury; Citrulline; Dementia; Homeostasis; Humans; Infant, Newborn; Liver; Lysine; Metabolism, Inborn Errors; Ornithine Carbamoyltransferase; Phosphotransferases; Succinates; Syndrome; Urea; Urease | 1974 |
Aminoacidurias due to inherited disorders of metabolism. 2.
Topics: Acidosis; Alanine; Amino Acid Metabolism, Inborn Errors; Arginase; Arginine; Carbamates; Citrulline; Dipeptides; Glutarates; Glycine; Histidine; Humans; Hydroxyproline; Hyperglycemia; Infant, Newborn; Keto Acids; Lysine; Malonates; Maple Syrup Urine Disease; Ornithine Carbamoyltransferase; Phosphotransferases; Proline; Sarcosine; Succinates; Urea; Valine | 1973 |
Arginnosuccinic aciduria.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Arginine; Blood Urea Nitrogen; Child, Preschool; Citrulline; Humans; Intellectual Disability; Lyases; Rats; Succinates | 1967 |
[Feeble mindedness caused by genetic disorders of amino acid metabolism].
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Citrulline; Glycine; Hartnup Disease; Histidine; Homocystinuria; Humans; Hydroxyproline; Intellectual Disability; Lysine; Maple Syrup Urine Disease; Methionine; Phenylketonurias; Proline; Sarcosine; Succinates; Transferases; Tryptophan; Valine | 1968 |
[Synthesis of urea in the cerebral tissue].
Topics: Animals; Arginine; Brain; Citrulline; Humans; Ornithine; Urea | 1969 |
[Hereditary enzyme defects of the urea cycle].
Topics: Adult; Ammonia; Arginase; Arginine; Child; Child, Preschool; Citrulline; Enzymes; Female; Humans; Infant; Infant, Newborn; Ligases; Lyases; Male; Metabolism, Inborn Errors; Ornithine; Ornithine Carbamoyltransferase; Phosphotransferases; Succinates; Transaminases; Urea | 1971 |
Hereditary metabolic disorders of the urea cycle.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginase; Arginine; Aspartic Acid; Carbamates; Citrulline; Humans; Ligases; Liver; Lyases; Models, Chemical; Ornithine Carbamoyltransferase; Phosphotransferases; Succinates; Urea | 1971 |
Can arginine and ornithine support gut functions?
Topics: Arginine; Citrulline; Enteral Nutrition; Humans; Intestinal Mucosa; Intestines; Nitric Oxide; Ornithine | 1994 |
Release of nitric oxide from astroglial cells: a key mechanism in neuroimmune disorders.
Topics: Animals; Arginine; Citrulline; Cyclic GMP; Invertebrates; NADP; Nerve Tissue Proteins; Nervous System; Neuronal Plasticity; Nitric Oxide; Nitric Oxide Synthase; Signal Transduction; Smell; Species Specificity | 1995 |
Aptamer structures from A to zeta.
Topics: Adenosine Triphosphate; Aptamers, Nucleotide; Arginine; Base Sequence; Binding Sites; Citrulline; Flavin Mononucleotide; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Oligonucleotides; RNA; Thrombin | 1996 |
Structure, recognition and adaptive binding in RNA aptamer complexes.
Topics: Adenosine Monophosphate; Arginine; Citrulline; Flavin Mononucleotide; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Proteins; RNA; Tobramycin | 1997 |
Alternative pathway therapy for urea cycle disorders.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Arginine; Benzoates; Benzoic Acid; Child; Citrulline; Combined Modality Therapy; Female; Humans; Male; Nitrogen; Phenylacetates; Phenylbutyrates; Urea | 1998 |
Catalysis by nitric oxide synthase.
Topics: Antioxidants; Arginine; Biopterins; Catalysis; Citrulline; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Heme; Hydrogen Peroxide; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase | 1998 |
Single-cell analyses of nitrergic neurons in simple nervous systems.
Topics: Animals; Arginine; Citrulline; Electrophoresis, Capillary; Models, Neurological; Mollusca; Neurons; Nitric Oxide; Nitric Oxide Synthase | 1999 |
A new decoration for nitric oxide synthase - a Zn(Cys)4 site.
Topics: Animals; Arginine; Binding Sites; Biopterins; Citrulline; Cysteine; Dimerization; Electron Transport; Macromolecular Substances; Models, Molecular; NADP; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Protein Conformation; Zinc | 1999 |
Tetrahydrobiopterin and endothelial nitric oxide synthase activity.
Topics: Antioxidants; Arginine; Biopterins; Citrulline; Coronary Vessels; Endothelium, Vascular; Enzyme Activation; Humans; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Vascular Diseases | 1999 |
Regulation of nitric oxide production by arginine metabolic enzymes.
Topics: Amino Acid Transport Systems, Basic; Animals; Arginase; Arginine; Carrier Proteins; Citrulline; Enzyme Inhibitors; Humans; Membrane Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II | 2000 |
Mammalian mitochondrial inner membrane cationic and neutral amino acid carriers.
Topics: Amino Acid Transport Systems; Amino Acid Transport Systems, Basic; Animals; Arginine; Biological Transport; Carnitine Acyltransferases; Carrier Proteins; Citrulline; Glutamine; Glycine; Humans; Intracellular Membranes; Membrane Proteins; Membrane Transport Proteins; Mitochondria | 2000 |
Citrullination: a small change for a protein with great consequences for rheumatoid arthritis.
Topics: Animals; Apoptosis; Arginine; Arthritis, Rheumatoid; Autoantibodies; Autoantigens; Citrulline; Humans | 2000 |
Nitric oxide synthase-independent generation of nitric oxide in muscle ischemia--reperfusion injury.
Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Isoenzymes; Mice; Muscle, Skeletal; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury | 2000 |
Arginine metabolism and the synthesis of nitric oxide in the nervous system.
Topics: Animals; Arginine; Brain; Central Nervous System; Citrulline; Humans; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Synthase | 2001 |
Cholinergic-nitrergic transmitter mechanisms in the cerebral circulation.
Topics: Acetylcholine; Arginine; Calcium Channels, N-Type; Cerebrovascular Circulation; Cholinergic Fibers; Citrulline; Humans; Neurons; Nitric Oxide; Receptors, Muscarinic; Telencephalon; Vasodilation | 2001 |
Macrophage arginine metabolism to ornithine/urea or nitric oxide/citrulline: a life or death issue.
Topics: Animals; Arginase; Arginine; Cell Death; Cell Survival; Citrulline; Humans; Lymphocytes; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine; Urea | 2001 |
[Mitochondrial urea cycle and related enzymes].
Topics: Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbamoyl-Phosphate Synthase (Ammonia); Citrulline; Humans; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; Nitrogen; Ornithine Carbamoyltransferase; Urea | 2002 |
Citrulline and DRIP-1 protein (ArgE homologue) in drought tolerance of wild watermelon.
Topics: Abscisic Acid; Acclimatization; Alanine; Amidohydrolases; Arginine; Brassicaceae; Carbon; Citrulline; Citrullus; Cucumis sativus; Disasters; gamma-Aminobutyric Acid; Gene Expression Regulation, Plant; Glutamine; Heat-Shock Proteins; Light; Models, Biological; Oxygen; Photosynthesis; Plant Proteins; Plants; Sodium Chloride; Water | 2002 |
Reduced arginine availability and nitric oxide production.
Topics: Amino Acid Transport Systems; Arginase; Arginine; Biological Availability; Citrulline; Humans; Membrane Proteins; Nitric Oxide | 2002 |
Isotopic investigation of nitric oxide metabolism in disease.
Topics: Arginine; Biomarkers; Citrulline; Humans; Isotope Labeling; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes | 2003 |
Roles of nitric oxide and superoxide in inflammation.
Topics: 2-Naphthylamine; Animals; Arginine; Blotting, Western; Capillary Permeability; Chemotaxis, Leukocyte; Citrulline; Fluorescent Dyes; Fluorometry; Inflammation; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Rats; Superoxides; Tyrosine | 2003 |
[Adult-onset type II citrullinemia].
Topics: Adult; Ammonia; Arginine; Brain; Calcium-Binding Proteins; Citrulline; Citrullinemia; Female; Humans; Liver; Liver Transplantation; Magnetic Resonance Imaging; Male; Middle Aged; Organic Anion Transporters | 2003 |
Arginine deficiency in preterm infants: biochemical mechanisms and nutritional implications.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Citrulline; Deficiency Diseases; Female; Glucocorticoids; Humans; Hydrocortisone; Hyperargininemia; Infant, Newborn; Infant, Premature; Intestinal Mucosa; Intestines; Nutritional Requirements; Ornithine-Oxo-Acid Transaminase; Pregnancy | 2004 |
Alternative nitric oxide-producing substrates for NO synthases.
Topics: Alkylation; Animals; Arginine; Binding Sites; Citrulline; Guanidines; Humans; Hydroxylamines; Isoenzymes; Mammals; Models, Molecular; Molecular Structure; NADP; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Structure-Activity Relationship; Substrate Specificity | 2004 |
Enzymes of the L-arginine to nitric oxide pathway.
Topics: Animals; Arginine; Citrulline; Humans; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Structure-Activity Relationship | 2004 |
Renal arginine metabolism.
Topics: Absorption; Animals; Arginine; Citrulline; Creatine; Humans; Kidney | 2004 |
Citrullinated proteins in rheumatoid arthritis.
Topics: Arginine; Arthritis, Rheumatoid; Autoimmunity; Citrulline; Genetic Predisposition to Disease; Humans; Hydrolases; Models, Biological; Peptides; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Synovial Membrane | 2005 |
Arginine deprivation and metabolomics: important aspects of intermediary metabolism in relation to the differential sensitivity of normal and tumour cells.
Topics: Arginine; Argininosuccinate Synthase; Cell Death; Cell Division; Citrulline; Humans; Neoplasms | 2005 |
Pegylated arginine deiminase: a novel anticancer enzyme agent.
Topics: Amino Acid Sequence; Amino Acids; Animals; Antineoplastic Agents; Arginine; Argininosuccinate Synthase; Carcinoma, Hepatocellular; Citrulline; Clinical Trials as Topic; Dexamethasone; Dogs; Drug Screening Assays, Antitumor; Drug Synergism; Drugs, Investigational; Humans; Hydrolases; Liver Neoplasms; Melanoma; Melanoma, Experimental; Mice; Mice, Nude; Molecular Sequence Data; Mycoplasma hominis; Neoplasm Proteins; Neoplasms; Nutritional Requirements; Polyethylene Glycols; Rabbits; Randomized Controlled Trials as Topic; Recombinant Proteins; Skin Neoplasms; Species Specificity; Treatment Outcome | 2006 |
L-arginine: a new opportunity in the management of clinical derangements in dialysis patients.
Topics: Adult; Aged; Animals; Arginine; Citrulline; Diabetic Nephropathies; Endothelium, Vascular; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide; Renal Dialysis | 2006 |
Histone citrullination by protein arginine deiminase: is arginine methylation a green light or a roadblock?
Topics: Arginine; Chemistry; Citrulline; Gene Expression Regulation, Enzymologic; Histones; Hydrolases; Methylation; Models, Chemical; Models, Molecular; Multigene Family; Protein Conformation; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Proteomics | 2006 |
Pharmacokinetics of arginine and related amino acids.
Topics: Arginine; Citrulline; Eating; Fasting; Humans; Ornithine | 2007 |
Adverse gastrointestinal effects of arginine and related amino acids.
Topics: Animals; Arginine; Citrulline; Gastrointestinal Diseases; Humans; Nitric Oxide | 2007 |
Asymmetric dimethylarginine (ADMA) in vascular, renal and hepatic disease and the regulatory role of L-arginine on its metabolism.
Topics: Arginine; Citrulline; Dietary Supplements; Hepatocytes; Homocysteine; Humans; Kidney Diseases; Liver Diseases; Nitric Oxide Synthase; Obesity; Risk Factors; Vascular Diseases | 2007 |
Specific amino acids in the critically ill patient--exogenous glutamine/arginine: a common denominator?
Topics: Acid-Base Equilibrium; Animals; Arginine; Citrulline; Critical Illness; Dipeptides; Enteral Nutrition; Gastrointestinal Tract; Glutamine; Glutathione; Humans; Oxidative Stress; Parenteral Nutrition; Taurine | 2007 |
Arginine homeostasis in allergic asthma.
Topics: Animals; Arginine; Asthma; Bronchial Hyperreactivity; Citrulline; Homeostasis; Humans; Hypersensitivity; Inflammation | 2008 |
Analysis of citrulline, arginine, and methylarginines using high-performance liquid chromatography.
Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Citrulline; Humans | 2008 |
Nitric oxide in plants: production and cross-talk with Ca2+ signaling.
Topics: Animals; Arabidopsis; Arginine; Calcium; Calcium-Transporting ATPases; Citrulline; Genome, Plant; Mammals; Nitrate Reductase; Nitric Oxide; Nitric Oxide Synthase; Nitriles; Nitrites; Plant Physiological Phenomena; Protein Kinases; Signal Transduction | 2008 |
Regulation of nitric oxide production in health and disease.
Topics: Animals; Arginase; Arginine; Ascorbic Acid; Biopterins; Citrulline; Diet; Dietary Fats; Endothelium; Humans; Hypertension; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Sepsis | 2010 |
Effect of intestinal resections on arginine metabolism: practical implications for nutrition support.
Topics: Arginine; Citrulline; Dietary Supplements; Humans; Intestinal Mucosa; Intestines; Nutritional Support; Postoperative Complications; Short Bowel Syndrome | 2010 |
Inhaled nitric oxide and related therapies.
Topics: Administration, Inhalation; Administration, Oral; Arginine; Cardiac Surgical Procedures; Child; Child, Preschool; Citrulline; Clinical Trials as Topic; Endothelium-Dependent Relaxing Factors; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn; Injections, Intravenous; Nitric Oxide; Postoperative Complications | 2010 |
Genetic background of tolerance breakdown in rheumatoid arthritis.
Topics: Animals; Arginine; Arthritis, Rheumatoid; Autoantibodies; Autoimmunity; Citrulline; Genetic Predisposition to Disease; Genome-Wide Association Study; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Hydrolases; Immune Tolerance; Lymphocytes; Mice; Multifactorial Inheritance; Peptides; Protein Tyrosine Phosphatase, Non-Receptor Type 22; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Receptors, Immunologic | 2010 |
[Anti-cyclic citrullinated peptide antibodies and rheumatoid arthritis].
Topics: Animals; Arginine; Arthritis, Rheumatoid; Autoantibodies; Biomarkers; Citrulline; Early Diagnosis; Humans; Hydrolases; Peptides, Cyclic; Prognosis; Protein-Arginine Deiminases; Reference Standards; Rheumatoid Factor; Sensitivity and Specificity | 2010 |
The 2009 ESPEN Sir David Cuthbertson. Citrulline: a new major signaling molecule or just another player in the pharmaconutrition game?
Topics: Animals; Arginine; Citrulline; Enterocytes; Glutamine; Humans; Intestinal Mucosa; Kidney; Nitric Oxide Synthase; Oxidative Stress; Protein Biosynthesis; Rats; Short Bowel Syndrome | 2010 |
The role of asymmetric dimethylarginine and arginine in the failing heart and its vasculature.
Topics: Amidohydrolases; Arginine; Citrulline; Coronary Vessels; Glutamic Acid; Heart Failure; Humans; Nitric Oxide; Reactive Oxygen Species | 2010 |
Citrullinated peptide and its relevance to rheumatoid arthritis: an update.
Topics: Arginine; Arthritis, Rheumatoid; Autoantibodies; Biomarkers; Citrulline; Epitopes; Genetic Predisposition to Disease; Humans; Peptides; Peptides, Cyclic; Predictive Value of Tests; Prognosis; Risk Assessment; Risk Factors | 2010 |
[Deimination or citrullination, a post-translational modification with many physiological and pathophysiological facets].
Topics: Animals; Arginine; Autoimmune Diseases; Body Water; Calcium; Chromatin; Citrulline; Conserved Sequence; Cornea; Epidermis; Evolution, Molecular; Gene Expression Regulation; Humans; Hydrolases; Isoenzymes; Mice; Myelin Proteins; Neoplasms; Nervous System Diseases; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 6; Protein-Arginine Deiminases; Skin Diseases | 2011 |
Measurement of in vivo nitric oxide synthesis in humans using stable isotopic methods: a systematic review.
Topics: Age Factors; Arginine; Arteries; Cardiovascular Diseases; Citrulline; Clinical Laboratory Techniques; Humans; Nitrates; Nitric Oxide; Oxygen; Radioisotopes; Reproducibility of Results; Vasodilation | 2011 |
Pharmaconutrition for the obese, critically ill patient.
Topics: Antioxidants; Arginine; Citrulline; Critical Care; Critical Illness; Dietary Proteins; Dietary Supplements; Enteral Nutrition; Fatty Acids, Unsaturated; Humans; Inflammatory Bowel Diseases; Intensive Care Units; Length of Stay; Leucine; Magnesium; Obesity; Oxidative Stress; Prebiotics; Probiotics; Treatment Outcome; United States; Ventilation; Zinc | 2011 |
Generation, translocation, and action of nitric oxide in living systems.
Topics: Arginine; Biological Transport; Citrulline; Guanylate Cyclase; Iron-Sulfur Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitrogen Oxides; Oxidation-Reduction; Protein Conformation; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase | 2011 |
Argininosuccinate lyase deficiency.
Topics: Arginine; Argininosuccinate Lyase; Argininosuccinic Acid; Argininosuccinic Aciduria; Child, Preschool; Citrulline; Cognition Disorders; Diet, Protein-Restricted; Fumarates; Genetic Testing; Glucose; Humans; Hyperammonemia; Hypertension; Infant; Infant, Newborn; Lipids; Liver Diseases; Liver Transplantation; Neonatal Screening; Phenylbutyrates; Sodium Benzoate | 2012 |
The effect of nitric-oxide-related supplements on human performance.
Topics: Arginine; Citrulline; Dietary Supplements; Endothelium-Dependent Relaxing Factors; Exercise Tolerance; Humans; Malates; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Sodium Nitrite; Task Performance and Analysis | 2012 |
Citrulline and arginine utility in treating nitric oxide deficiency in mitochondrial disorders.
Topics: Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Citrulline; Clinical Trials as Topic; Electron Transport; Electron Transport Complex IV; Humans; MELAS Syndrome; Mitochondria; Nitric Oxide; Nitric Oxide Synthase Type III; Reactive Nitrogen Species | 2012 |
Citrulline: from metabolism to therapeutic use.
Topics: Aging; Animals; Arginine; Biological Transport; Cardiovascular Diseases; Citrulline; Humans; Intestinal Mucosa; Models, Animal; Muscle, Skeletal; Protein Biosynthesis; Sarcopenia | 2013 |
Arginine and citrulline supplementation in sports and exercise: ergogenic nutrients?
Topics: Arginine; Citrulline; Dietary Supplements; Exercise; Exercise Tolerance; Humans; Nitric Oxide; Nitric Oxide Synthase; Sports Medicine; Task Performance and Analysis | 2012 |
Chemical and biological methods to detect post-translational modifications of arginine.
Topics: Animals; Antibodies; Arginine; Citrulline; Fluorescent Dyes; Humans; Peptides; Protein Processing, Post-Translational | 2014 |
Arginine and nitric oxide synthase: regulatory mechanisms and cardiovascular aspects.
Topics: Adipose Tissue; Arginine; Biological Transport; Biopterins; Cardiovascular Diseases; Cardiovascular System; Citrulline; Diet; Dietary Supplements; Humans; Nitric Oxide Synthase | 2014 |
Mitochondria: role of citrulline and arginine supplementation in MELAS syndrome.
Topics: Arginine; Citrulline; Humans; MELAS Syndrome; Mitochondria; Nitric Oxide | 2014 |
Erectile hydraulics: maximizing inflow while minimizing outflow.
Topics: Age Factors; Androgens; Animals; Antioxidants; Arginine; Blood Vessels; Citrulline; Diet; Erectile Dysfunction; Exercise Therapy; Fatty Acids, Omega-3; Folic Acid; Humans; Male; Nitric Oxide; Obesity; Organ Sparing Treatments; Pelvic Floor; Penile Erection; Penis; Phosphodiesterase 5 Inhibitors; Prostatectomy; Regional Blood Flow; Smoking; Testosterone; Vasodilator Agents | 2014 |
[The role of L-arginine and L-citrulline on atherosclerosis].
Topics: Animals; Arginine; Atherosclerosis; Citrulline; Glucose; Humans; Nitric Oxide | 2014 |
Biological relevance of citrullinations: diagnostic, prognostic and therapeutic options.
Topics: Arginine; Arthritis, Rheumatoid; Autoantibodies; Benzamidines; Biomarkers; Citrulline; Enzyme Inhibitors; Fibrosis; Humans; Hydrolases; Isoenzymes; Multiple Sclerosis; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Spondylitis, Ankylosing | 2015 |
The role of immunomodulators on intestinal barrier homeostasis in experimental models.
Topics: Animals; Arginine; Bifidobacterium; Citrulline; Disease Models, Animal; Epithelial Cells; Fatty Acids, Omega-3; Glutamine; Homeostasis; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Intestinal Mucosa; Lactobacillus; Linoleic Acids, Conjugated; Permeability; Probiotics; Saccharomyces; Tryptophan | 2015 |
Arginine and citrulline and the immune response in sepsis.
Topics: Arginine; Citrulline; Endotoxemia; Humans; Immunity; Inflammation; Macrophages; Nitric Oxide; Sepsis; T-Lymphocytes | 2015 |
Detection and identification of protein citrullination in complex biological systems.
Topics: Animals; Arginine; Citrulline; Humans; Mass Spectrometry; Protein Processing, Post-Translational; Proteins | 2016 |
Interrelationships between glutamine and citrulline metabolism.
Topics: Animals; Arginine; Citrulline; Dietary Supplements; Gastrointestinal Tract; Glutamine; Humans; Kidney | 2016 |
Regulation of the proteome by amino acids.
Topics: Animals; Arginine; Citrulline; Glutamine; Humans; Leucine; Methionine; Protein Biosynthesis; Proteome; Signal Transduction; TOR Serine-Threonine Kinases | 2016 |
Indications and contraindications for infusing specific amino acids (leucine, glutamine, arginine, citrulline, and taurine) in critical illness.
Topics: Arginine; Citrulline; Critical Care; Critical Illness; Dietary Supplements; Enteral Nutrition; Glutamine; Humans; Intensive Care Units; Leucine; Parenteral Nutrition; Randomized Controlled Trials as Topic; Taurine | 2016 |
Influence of L-citrulline and watermelon supplementation on vascular function and exercise performance.
Topics: Adult; Arginine; Biological Availability; Blood Pressure; Citrulline; Citrullus; Dietary Supplements; Exercise; Exercise Tolerance; Humans; Nitric Oxide; Regional Blood Flow | 2017 |
Potential Nutrients for Preventing or Treating Bronchopulmonary Dysplasia.
Topics: Acetylcysteine; Antioxidants; Arginine; Bronchopulmonary Dysplasia; Citrulline; Cysteine; Fatty Acids, Unsaturated; Glutamine; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn; Infant, Premature; Inositol; Selenium; Vitamin A; Vitamin B Complex | 2017 |
Assessment of Nitric Oxide Production in Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes Syndrome with the Use of a Stable Isotope Tracer Infusion Technique.
Topics: Arginine; Citrulline; Diagnostic Techniques, Radioisotope; Humans; MELAS Syndrome; Mitochondria; Nitric Oxide | 2017 |
Citrulline in health and disease. Review on human studies.
Topics: Anabolic Agents; Animals; Arginine; Athletic Performance; Carbamoyl-Phosphate Synthase I Deficiency Disease; Cardiovascular Diseases; Citrulline; Endothelial Cells; Enterocytes; Female; Humans; Immunity; Male; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Oxidative Stress; Protein Biosynthesis; Urea Cycle Disorders, Inborn | 2018 |
Peptidylarginine deiminases and deiminated proteins at the epidermal barrier.
Topics: Animals; Arginine; Arthritis, Rheumatoid; Calcium; Citrulline; Epidermal Cells; Epidermis; Filaggrin Proteins; Gene Expression Profiling; Gene Expression Regulation; Humans; Hydrolases; Inflammation; Mice; Neoplasms; Neurodegenerative Diseases; Protein Processing, Post-Translational; Protein-Arginine Deiminases | 2018 |
Effectiveness of citrulline and N-carbamoyl glutamate as arginine precursors on reproductive performance in mammals: A systematic review.
Topics: Animal Feed; Animals; Arginine; Birth Weight; Citrulline; Dietary Supplements; Female; Fetal Development; Fetus; Glutamates; Goats; Mammals; Pregnancy; Rats; Reproduction; Sheep | 2018 |
Perspective: L-arginine and L-citrulline Supplementation in Pregnancy: A Potential Strategy to Improve Birth Outcomes in Low-Resource Settings.
Topics: Arginine; Citrulline; Dietary Supplements; Female; Fetal Development; Fetal Growth Retardation; Health Resources; Humans; Infant, Low Birth Weight; Infant, Newborn; Maternal Nutritional Physiological Phenomena; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Premature Birth; Prenatal Care | 2019 |
Citrullinemia type I is associated with a novel splicing variant, c.773 + 4A > C, in ASS1: a case report and literature review.
Topics: Arginine; Argininosuccinate Synthase; Asian People; Base Sequence; China; Citrulline; Citrullinemia; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Homozygote; Humans; Infant, Newborn; Language Development Disorders; Male; Mutation; Pedigree; Phenotype; Phenylalanine; RNA Splicing | 2019 |
The Effects of Oral l-Arginine and l-Citrulline Supplementation on Blood Pressure.
Topics: Administration, Oral; Antihypertensive Agents; Arginine; Blood Pressure; Citrulline; Humans; Hypertension | 2019 |
Citrulline production and protein homeostasis.
Topics: Animals; Arginine; Citrulline; Humans; Intestinal Mucosa; Macrophages; Mice; Nitric Oxide; Proteostasis; Rats; Swine | 2019 |
[The effect of supplementation with L-arginine and L-citrulline on physical performance: a systematic review].
Topics: Arginine; Citrulline; Dietary Supplements; Humans; Physical Functional Performance | 2019 |
Effects of Citrulline Supplementation on Exercise Performance in Humans: A Review of the Current Literature.
Topics: Amino Acids, Branched-Chain; Antioxidants; Arginine; Biomarkers; Citrulline; Dietary Supplements; Drug Therapy, Combination; Exercise; Humans; Malates; Muscle, Skeletal; Nitrates | 2020 |
Therapeutic Potential of Citrulline as an Arginine Supplement: A Clinical Pharmacology Review.
Topics: Adolescent; Adult; Arginine; Child; Citrulline; Female; Humans; Male; Pharmacology, Clinical; Young Adult | 2020 |
L-Citrulline Supports Vascular and Muscular Benefits of Exercise Training in Older Adults.
Topics: Aging; Arginine; Biological Availability; Body Mass Index; Citrulline; Dietary Supplements; Endothelium, Vascular; Exercise; Humans; Muscle Proteins; Muscle Strength; Muscle, Skeletal; Nitric Oxide; Oxygen Consumption; Physical Conditioning, Human | 2020 |
Endogenous flux of nitric oxide: Citrulline is preferred to Arginine.
Topics: Arginase; Arginine; Citrulline; Nitric Oxide; Nitric Oxide Synthase | 2021 |
The roles of PAD2- and PAD4-mediated protein citrullination catalysis in cancers.
Topics: Animals; Arginine; Citrulline; Humans; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminase Type 4 | 2021 |
Chemical biology of protein citrullination by the protein A arginine deiminases.
Topics: Animals; Arginine; Autoimmune Diseases; Catalysis; Citrullination; Citrulline; Epigenesis, Genetic; Humans; Neoplasms; Neurodegenerative Diseases; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Proteins | 2021 |
NO, way to go: critical amino acids to replenish nitric oxide production in treating mucositis.
Topics: Arginine; Citrulline; Glutamine; Humans; Mucositis; Nitric Oxide | 2021 |
Effects of L-Citrulline Supplementation and Aerobic Training on Vascular Function in Individuals with Obesity across the Lifespan.
Topics: Adolescent; Adult; Aged; Arginine; Atherosclerosis; Blood Pressure; Cardiometabolic Risk Factors; Cardiovascular Diseases; Child; Citrulline; Dietary Supplements; Endothelium, Vascular; Exercise; Female; Humans; Hypertension; Longevity; Male; Metabolic Diseases; Middle Aged; Nitric Oxide; Obesity; Vascular Stiffness; Vasodilation; Young Adult | 2021 |
Watermelon and L-Citrulline in Cardio-Metabolic Health: Review of the Evidence 2000-2020.
Topics: Animals; Arginine; Citrulline; Citrullus; Fruit; Humans; Nitric Oxide | 2021 |
Effect of food sources of nitrate, polyphenols, L-arginine and L-citrulline on endurance exercise performance: a systematic review and meta-analysis of randomised controlled trials.
Topics: Arginine; Citrulline; Exercise Tolerance; Female; Food; Food Analysis; Humans; Male; Nitrates; Nitric Oxide; Physical Endurance; Polyphenols; Randomized Controlled Trials as Topic | 2021 |
Current Evidence of Watermelon (
Topics: Arginine; Citrulline; Citrullus; Eating; Food Technology; Technology | 2022 |
Peptidylarginine deiminase enzymes and citrullinated proteins in female reproductive physiology and associated diseases†.
Topics: Animals; Arginine; Citrullination; Citrulline; Female; Histones; Hydrolases; Protein Processing, Post-Translational; Protein-Arginine Deiminases | 2022 |
Homoarginine in health and disease.
Topics: Adult; Arginine; Cardiovascular System; Citrulline; Homoarginine; Humans; Kidney; Male | 2023 |
Metabolic effects of L-citrulline in type 2 diabetes.
Topics: Animals; Arginine; Citrulline; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Muscle, Skeletal | 2023 |
Supplementation with Nitric Oxide Precursors for Strength Performance: A Review of the Current Literature.
Topics: Arginine; Citrulline; Dietary Supplements; Humans; Muscle, Skeletal; Nitrates; Nitric Oxide; Nitric Oxide Synthase | 2023 |
Dietary Arginine and Citrulline Supplements for Cardiovascular Health and Athletic Performance: A Narrative Review.
Topics: Aged; Arginine; Athletic Performance; Citrulline; Dietary Supplements; Humans | 2023 |
Tolerable Upper Intake Level for Individual Amino Acids in Humans: A Narrative Review of Recent Clinical Studies.
Topics: Aged; Arginine; Citrulline; Histidine; Humans; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Serine; Tryptophan | 2023 |
Absence of Effects of L-Arginine and L-Citrulline on Inflammatory Biomarkers and Oxidative Stress in Response to Physical Exercise: A Systematic Review with Meta-Analysis.
Topics: Adolescent; Arginine; Biomarkers; Citrulline; Dietary Supplements; Exercise; Humans; Oxidative Stress; Randomized Controlled Trials as Topic | 2023 |
A Critical Review on Vasoactive Nutrients for the Management of Endothelial Dysfunction and Arterial Stiffness in Individuals under Cardiovascular Risk.
Topics: Arginine; Cardiovascular Diseases; Citrulline; Endothelium, Vascular; Heart Disease Risk Factors; Humans; Nitric Oxide; Risk Factors; Vascular Stiffness; Vasodilation | 2023 |
Pathophysiology of Preeclampsia and L-Arginine/L-Citrulline Supplementation as a Potential Strategy to Improve Birth Outcomes.
Topics: Arginine; Citrulline; Dietary Supplements; Female; Humans; Placenta; Placenta Growth Factor; Pre-Eclampsia; Pregnancy; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2023 |
73 trial(s) available for citrulline and arginine
| Article | Year |
|---|---|
Umbilical arteries of babies born to cigarette smokers generate less prostacyclin and contain less arginine and citrulline compared with those of babies born to control subjects.
Topics: Adolescent; Adult; Arginine; Citrulline; Cysteine; Epoprostenol; Female; Humans; Infant, Newborn; Pregnancy; Smoking; Umbilical Arteries | 1995 |
The hypotensive effect of L-arginine is associated with increased expired nitric oxide in humans.
Topics: Adult; Arginine; Blood Pressure; Breath Tests; Citrulline; Cross-Over Studies; Humans; Hypotension; Male; Nitric Oxide | 1996 |
Haemodynamic and biochemical responses to L-arginine and L-lysine infusions in normal subjects: L-arginine-induced vasodilatation cannot be explained by non-specific effects of cationic amino acids.
Topics: Adult; Arginine; Atrial Natriuretic Factor; Blood Pressure; Citrulline; Cyclic GMP; Electrolytes; Extracellular Space; Female; Heart Rate; Humans; Lysine; Male; Nitric Oxide; Vascular Resistance; Vasodilation | 1997 |
L-arginine infusion decreases platelet aggregation through an intraplatelet nitric oxide release.
Topics: Adenosine Diphosphate; Adult; Arginine; Blood Pressure; Citrulline; Collagen; Diastole; Female; Humans; Infusions, Intravenous; Nitric Oxide; Nitrites; Placebos; Platelet Aggregation; Systole; Time Factors | 1997 |
L-arginine infusion dilates coronary vasculature in patients undergoing coronary bypass surgery.
Topics: Aged; Arginine; Citrulline; Coronary Artery Bypass; Coronary Vessels; Humans; Middle Aged; Nitric Oxide; Prospective Studies; Vasodilation | 1999 |
Indices of activity of the nitric oxide system in hemodialysis patients.
Topics: Arginine; Blood Pressure; Citrulline; Cyclic GMP; Diet; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Renal Dialysis; Second Messenger Systems | 1999 |
Indirect evidence that estrogen replacement therapy stimulates nitric oxide synthase in postmenopausal women.
Topics: Arginine; Body Mass Index; Chromatography, High Pressure Liquid; Citrulline; Cross-Over Studies; Estradiol; Estrogen Replacement Therapy; Female; Follicle Stimulating Hormone; Humans; Middle Aged; Nitric Oxide Synthase; Placebos; Postmenopause | 2000 |
Nitric oxide synthesis inhibition does not impair water immersion-induced renal vasodilation in humans.
Topics: Adult; Arginine; Blood Pressure; Citrulline; Diuresis; Enzyme Inhibitors; Hormones; Humans; Immersion; Male; Natriuresis; Nitric Oxide; omega-N-Methylarginine; Renal Circulation; Vascular Resistance; Vasodilation; Water | 2000 |
L-arginine reduces exercise-induced increase in plasma lactate and ammonia.
Topics: Adult; Ammonia; Arginine; Citrulline; Double-Blind Method; Exercise; Humans; Lactates; Male; Muscle, Skeletal; Nitric Oxide; Ornithine | 2002 |
Oral arginine reduces systemic blood pressure in type 2 diabetes: its potential role in nitric oxide generation.
Topics: Adult; Arginine; Blood Pressure; C-Peptide; Citrulline; Cross-Over Studies; Diabetes Mellitus, Type 2; Humans; Hypertension; Insulin; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Prospective Studies | 2002 |
Reduced myocardial and systemic L-arginine uptake in heart failure.
Topics: Arginine; Biological Transport; Biopsy; Cardiac Output; Catheterization; Cationic Amino Acid Transporter 1; Cationic Amino Acid Transporter 2; Chronic Disease; Citrulline; Down-Regulation; Heart Failure; Heart Ventricles; Humans; Infusions, Intravenous; Kinetics; Metabolic Clearance Rate; Middle Aged; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Reference Values; RNA, Messenger; Tritium | 2002 |
Effects of ACE inhibition and AT1-receptor blockade on haemodynamic responses to L-arginine in Type 1 diabetes.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Arginine; Blood Pressure; Citrulline; Cross-Over Studies; Diabetes Mellitus, Type 1; Drug Synergism; Hemodynamics; Hormones; Humans; Kidney; Losartan; Male; Nitric Oxide; Ramipril | 2004 |
Hypocitrullinemia in patients with MELAS: an insight into the "MELAS paradox".
Topics: Adult; Amino Acids; Arginine; Chromatography, High Pressure Liquid; Citrulline; Female; Humans; Male; MELAS Syndrome; Nitric Oxide; Prostaglandin-Endoperoxide Synthases | 2005 |
Arginine supplementation does not enhance serum nitric oxide levels in elderly nursing home residents with pressure ulcers.
Topics: Administration, Oral; Aged; Arginine; Citrulline; Dietary Supplements; Drug Monitoring; Female; Florida; Geriatric Assessment; Humans; Inflammation; Lymphocyte Activation; Male; Mitogens; Neutrophil Activation; Nitric Oxide; Nursing Homes; Nutrition Assessment; Nutritional Status; Ornithine; Pressure Ulcer; Respiratory Burst; Time Factors | 2005 |
Influence of pegylated interferon-alpha therapy on plasma levels of citrulline and arginine in melanoma patients.
Topics: Antiviral Agents; Arginine; Citrulline; Female; Humans; Interferon alpha-2; Interferon-alpha; Male; Melanoma; Nitric Oxide; Polyethylene Glycols; Recombinant Proteins; Risk Factors; Time Factors | 2007 |
Nitric oxide precursors and congenital heart surgery: a randomized controlled trial of oral citrulline.
Topics: Administration, Oral; Arginine; Blood Pressure; Cardiac Surgical Procedures; Child, Preschool; Citrulline; Double-Blind Method; Female; Fontan Procedure; Humans; Hypertension, Pulmonary; Infant; Male; Multivariate Analysis; Pilot Projects; Postoperative Complications | 2006 |
Watermelon consumption increases plasma arginine concentrations in adults.
Topics: Adult; Aged; Arginine; Beverages; Citrulline; Citrullus; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Ornithine | 2007 |
Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.
Topics: Administration, Oral; Arginine; Citrulline; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Placebos; Vasodilation | 2008 |
Dose-ranging effects of citrulline administration on plasma amino acids and hormonal patterns in healthy subjects: the Citrudose pharmacokinetic study.
Topics: Adult; Amino Acids; Analysis of Variance; Area Under Curve; Arginine; Blood Glucose; Calcium; Citrulline; Creatinine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Growth Hormone; Humans; Insulin; Kidney; Male; Metabolic Clearance Rate; Nitrogen; Ornithine | 2008 |
Adaptation to a long term (4 weeks) arginine- and precursor (glutamate, proline and aspartate)-free diet.
Topics: Adult; Analysis of Variance; Arginine; Aspartic Acid; Carbon Isotopes; Citrulline; Diet; Dietary Proteins; Female; Glutamic Acid; Homeostasis; Humans; Infusions, Intravenous; Isotope Labeling; Kinetics; Leucine; Male; Nitrogen Isotopes; Oxidation-Reduction; Proline; Time Factors; Urea | 2008 |
No effect of short-term arginine supplementation on nitric oxide production, metabolism and performance in intermittent exercise in athletes.
Topics: Ammonia; Arginine; Citrulline; Cross-Over Studies; Exercise; Humans; Lactates; Male; Martial Arts; Nitric Oxide; Placebos; Young Adult | 2009 |
Effects of L-citrulline oral supplementation on polymorphonuclear neutrophils oxidative burst and nitric oxide production after exercise.
Topics: Administration, Oral; Arginine; Bicycling; Citrulline; Creatine Kinase; Dietary Supplements; DNA Damage; Double-Blind Method; Exercise; Humans; L-Lactate Dehydrogenase; Malates; Male; Malondialdehyde; Neutrophil Activation; Neutrophils; Nitric Oxide; Nitrites; Respiratory Burst; Time Factors; Young Adult | 2009 |
L-citrulline-malate influence over branched chain amino acid utilization during exercise.
Topics: Administration, Oral; Amino Acids, Branched-Chain; Arginine; Bicycling; Biomarkers; Citrulline; Creatinine; Dietary Proteins; Dietary Supplements; Double-Blind Method; Exercise; Human Growth Hormone; Humans; Insulin; Malates; Male; Muscle, Skeletal; Nitrites; Ornithine; Time Factors; Urea; Young Adult | 2010 |
Effect of oral arginine supplementation on exhaled nitric oxide concentration in sickle cell anemia and acute chest syndrome.
Topics: Acute Chest Syndrome; Acute Disease; Administration, Oral; Adolescent; Anemia, Sickle Cell; Arginine; Aspartic Acid; Breath Tests; Child; Citrulline; Female; Glutamic Acid; Humans; Male; Nitrates; Nitric Oxide; Nitrites; Ornithine; Young Adult | 2010 |
Elevated levels of asymmetric dimethylarginine in chronic heart failure: a pathophysiologic link between oxygen radical load and impaired vasodilator capacity and the therapeutic effect of allopurinol.
Topics: Aged; Allopurinol; Arginine; Chronic Disease; Citrulline; Cross-Sectional Studies; Double-Blind Method; Female; Free Radical Scavengers; Heart Failure; Humans; Male; Middle Aged; Reactive Oxygen Species; Uric Acid; Vasodilation | 2010 |
The effect of L-arginine and citrulline on endothelial function in patients in heart failure with preserved ejection fraction.
Topics: Aged; Arginine; Citrulline; Echocardiography; Endothelium, Vascular; Female; Fingers; Heart Failure; Heart Failure, Diastolic; Humans; Male; Middle Aged; Photoplethysmography; Stroke Volume; Vasodilation | 2010 |
No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers.
Topics: Area Under Curve; Arginine; Biomarkers; Citrulline; Cyclic GMP; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites | 2010 |
Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men.
Topics: Ankle Brachial Index; Arginine; Blood Pressure; Citrulline; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type III; Placebos; Pulsatile Flow; Vascular Stiffness | 2012 |
Effect of L-arginine or L-citrulline oral supplementation on blood pressure and right ventricular function in heart failure patients with preserved ejection fraction.
Topics: Administration, Oral; Aged; Arginine; Blood Pressure; Chi-Square Distribution; Citrulline; Dietary Supplements; Echocardiography, Doppler; Exercise Test; Female; Heart Failure; Humans; Male; Mexico; Middle Aged; Pulmonary Artery; Radionuclide Ventriculography; Stroke Volume; Time Factors; Treatment Outcome; Ventricular Function, Right | 2010 |
Arginine synthesis from enteral glutamine in healthy adults in the fed state.
Topics: Arginine; Carbon Isotopes; Citrulline; Eating; Glutamic Acid; Glutamine; Humans; Ketoglutaric Acids; Male; Models, Biological; Nitrogen Isotopes; Ornithine; Young Adult | 2011 |
Watermelon extract supplementation reduces ankle blood pressure and carotid augmentation index in obese adults with prehypertension or hypertension.
Topics: Administration, Oral; Arginine; Blood Pressure; Brachial Artery; Carotid Arteries; Citrulline; Citrullus; Comorbidity; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Obesity; Plant Extracts | 2012 |
Multifactorial risk factor intervention in patients with Type 2 diabetes improves arginine bioavailability ratios.
Topics: Aged; Anticholesteremic Agents; Arginine; Biological Availability; Blood Pressure; Cholesterol, LDL; Citrulline; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Ornithine; Prospective Studies; Risk Factors; Time Factors | 2012 |
High citrulline-to-arginine ratio associated with blood pressure abnormalities in children with early chronic kidney disease.
Topics: Adolescent; Arginine; Biomarkers; Blood Pressure; Child; Child, Preschool; Citrulline; Female; Humans; Hypertension; Male; Renal Insufficiency, Chronic | 2013 |
Oral L-arginine supplementation in patients with mild arterial hypertension and its effect on plasma level of asymmetric dimethylarginine, L-citruline, L-arginine and antioxidant status.
Topics: Administration, Oral; Adult; Antioxidants; Arginine; Blood Pressure Monitoring, Ambulatory; Citrulline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Male | 2012 |
Improvement of ventricular function in systolic heart failure patients with oral L-citrulline supplementation.
Topics: Administration, Oral; Aged; Arginine; Case-Control Studies; Citrulline; Dietary Supplements; Endothelium, Vascular; Female; Follow-Up Studies; Heart Failure, Systolic; Hemodynamics; Humans; Male; Middle Aged; Nitric Oxide; Outpatients; Photoplethysmography; Radionuclide Imaging; Stroke Volume; Treatment Outcome; Ventricular Function, Left | 2012 |
Effects of watermelon supplementation on arterial stiffness and wave reflection amplitude in postmenopausal women.
Topics: Ankle Brachial Index; Aorta; Arginine; Blood Pressure; Citrulline; Citrullus; Cross-Over Studies; Dietary Supplements; Female; Fruit; Humans; Hypertension; Middle Aged; Obesity; Plant Extracts; Postmenopause; Pulse Wave Analysis; Vascular Stiffness | 2013 |
Arginine appearance and nitric oxide synthesis in critically ill infants can be increased with a protein-energy-enriched enteral formula.
Topics: Arginine; Citrulline; Critical Illness; Dietary Proteins; Dietary Supplements; Energy Intake; Enteral Nutrition; Female; Food, Fortified; Humans; Infant; Infant Formula; Intensive Care Units, Pediatric; Kinetics; Male; Nitric Oxide; Respiratory Insufficiency; Respiratory Syncytial Virus Infections | 2013 |
Lady Prelox® improves sexual function in generally healthy women of reproductive age.
Topics: Adult; Antioxidants; Arginine; Citrulline; Dietary Supplements; Dyspareunia; Female; Flavonoids; Free Radicals; Humans; Libido; Middle Aged; Oxidative Stress; Sexual Dysfunction, Physiological; Surveys and Questionnaires | 2013 |
L-citrulline improves splanchnic perfusion and reduces gut injury during exercise.
Topics: Administration, Oral; Adult; Arginine; Bicycling; Citrulline; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Enterocytes; Exercise; Fatty Acid-Binding Proteins; Humans; Intestine, Small; Male; Microcirculation; Splanchnic Circulation; Young Adult | 2014 |
Citrulline stimulates muscle protein synthesis in the post-absorptive state in healthy people fed a low-protein diet - A pilot study.
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Citrulline; Cross-Over Studies; Diet, Protein-Restricted; Dietary Proteins; Female; Humans; Insulin; Insulin-Like Growth Factor I; Male; Mitochondrial Proteins; Muscle Proteins; Ornithine; Phenylalanine; Pilot Projects; Protein Biosynthesis; Tyrosine; Young Adult | 2015 |
Arginine infusion in patients with septic shock increases nitric oxide production without haemodynamic instability.
Topics: Aged; Arginine; Blood Pressure; Case-Control Studies; Citrulline; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; Nitric Oxide; Shock, Septic; Urea | 2015 |
Digital plethysmography and arginine metabolism in prehypertension: effect of nebivolol therapy.
Topics: Adult; Antihypertensive Agents; Arginine; Benzopyrans; Blood Pressure; Citrulline; Endothelium, Vascular; Ethanolamines; Female; Humans; Male; Middle Aged; Nebivolol; Nitric Oxide; Plethysmography; Prehypertension; Prospective Studies; Regional Blood Flow | 2015 |
Sperm quality in men is improved by supplementation with a combination of L-arginine, L-citrullin, roburins and Pycnogenol®.
Topics: Adult; Arginine; Aspartic Acid; Citrulline; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Drug Combinations; Flavonoids; Humans; Infertility, Male; Male; Middle Aged; Phytotherapy; Plant Extracts; Quercus; Semen Analysis | 2014 |
Improvement of erectile function by a combination of French maritime pine bark and roburins with aminoacids.
Topics: Adult; Arginine; Aspartic Acid; Citrulline; Cross-Over Studies; Double-Blind Method; Drug Combinations; Erectile Dysfunction; Flavonoids; Humans; Male; Middle Aged; Penile Erection; Phytotherapy; Pinus; Plant Extracts; Quality of Life; Quercus; Surveys and Questionnaires; Tannins; Treatment Outcome; Vasodilator Agents | 2015 |
l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans.
Topics: Administration, Oral; Adolescent; Arginine; Bicycling; Biomarkers; Blood Pressure; Citrulline; Cross-Over Studies; Dietary Supplements; Double-Blind Method; England; Exercise; Exercise Tolerance; Humans; Kinetics; Male; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; Oxygen Consumption; Performance-Enhancing Substances; Spectroscopy, Near-Infrared; Treatment Outcome; Young Adult | 2015 |
Combined L-citrulline and glutathione supplementation increases the concentration of markers indicative of nitric oxide synthesis.
Topics: Adolescent; Adult; Animals; Arginine; Biomarkers; Body Mass Index; Citrulline; Cyclic GMP; Dietary Supplements; Double-Blind Method; Glutathione; Healthy Volunteers; Human Umbilical Vein Endothelial Cells; Humans; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Resistance Training; Young Adult | 2015 |
Beneficial Effects of Early Enteral Nutrition After Major Rectal Surgery: A Possible Role for Conditionally Essential Amino Acids? Results of a Randomized Clinical Trial.
Topics: Aged; Amino Acids; Anastomotic Leak; Arginine; Citrulline; Enteral Nutrition; Female; Glutamine; Humans; Ileus; Length of Stay; Male; Middle Aged; Parenteral Nutrition; Postoperative Care; Prospective Studies; Rectal Neoplasms; Time Factors; Treatment Outcome | 2016 |
Watermelon extract reduces blood pressure but does not change sympathovagal balance in prehypertensive and hypertensive subjects.
Topics: Arginine; Blood Pressure; Blood Pressure Determination; Citrulline; Citrullus; Dietary Supplements; Double-Blind Method; Female; Heart; Heart Rate; Humans; Hypertension; Male; Middle Aged; Sympathetic Nervous System | 2016 |
Actylise treatment does not influence nitric oxide metabolites serum level.
Topics: Aged; Arginine; Citrulline; Female; Humans; Male; Nitric Oxide; Stroke; Tissue Plasminogen Activator | 2016 |
Prevention of perceptual-motor decline by branched-chain amino acids, arginine, citrulline after tennis match.
Topics: Adult; Amino Acids, Branched-Chain; Arginine; Citrulline; Dietary Supplements; Fatigue; Humans; Hyperammonemia; Male; Psychomotor Performance; Single-Blind Method; Sports Nutritional Physiological Phenomena; Tennis | 2017 |
Branched-chain amino acids, arginine, citrulline alleviate central fatigue after 3 simulated matches in taekwondo athletes: a randomized controlled trial.
Topics: Amino Acids, Branched-Chain; Arginine; Athletes; Athletic Performance; Citrulline; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Exercise Test; Humans; Male; Martial Arts; Muscle Fatigue; Physical Endurance; Sports Nutritional Physiological Phenomena; Taiwan; Young Adult | 2016 |
The effects on plasma L-arginine levels of combined oral L-citrulline and L-arginine supplementation in healthy males.
Topics: Administration, Oral; Adult; Arginine; Citrulline; Dietary Supplements; Drug Interactions; Humans; Male; Young Adult | 2017 |
Effects of linagliptin on endothelial function and postprandial lipids in coronary artery disease patients with early diabetes: a randomized, placebo-controlled, double-blind trial.
Topics: Aged; Arginine; Austria; Biomarkers; Blood Glucose; Citrulline; Coronary Artery Disease; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Endothelium, Vascular; Female; Glycated Hemoglobin; Humans; Linagliptin; Lipids; Male; Middle Aged; Ornithine; Postprandial Period; Prospective Studies; Time Factors; Treatment Outcome; Vasodilation | 2018 |
Effects of single and combined metformin and L-citrulline supplementation on L-arginine-related pathways in Becker muscular dystrophy patients: possible biochemical and clinical implications.
Topics: Adult; Amidinotransferases; Arginine; Citrulline; Creatinine; Dietary Supplements; Female; Glycine; Guanidinoacetate N-Methyltransferase; Homoarginine; Humans; Male; Metformin; Middle Aged; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Nitrates; Nitric Oxide Synthase Type I; Treatment Outcome; Young Adult | 2018 |
A combination of oral L-citrulline and L-arginine improved 10-min full-power cycling test performance in male collegiate soccer players: a randomized crossover trial.
Topics: Administration, Oral; Adolescent; Adult; Arginine; Citrulline; Drug Combinations; Exercise Tolerance; Humans; Male; Soccer | 2019 |
Quantitation of the arginine family amino acids in the blood of full-term infants perinatally in relation to their birth weight.
Topics: Arginine; Biomarkers; Birth Weight; Citrulline; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Infant, Newborn; Male; Ornithine; Prognosis; Proline | 2019 |
Inter-Individual Responses to Citrulline Malate Oral Supplementation on Post-Exercise Hypotension in Hypertensives: A 24-Hour Analysis.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anthropometry; Arginine; Blood Pressure; Citrulline; Double-Blind Method; Exercise; Exercise Test; Female; Humans; Hypertension; Malates; Male; Middle Aged; Nitric Oxide; Placebo Effect; Post-Exercise Hypotension; Reference Values; Statistics, Nonparametric; Time Factors; Treatment Outcome; Vasodilator Agents | 2019 |
L-Citrulline increases nitric oxide and improves control in obese asthmatics.
Topics: Adult; Aged; Arginine; Asthma; Citrulline; Dietary Supplements; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Obesity; Oxidative Stress; Pilot Projects; Proof of Concept Study; Severity of Illness Index; Treatment Outcome; Young Adult | 2019 |
Arginine, ornithine and citrulline supplementation in rainbow trout: Free amino acid dynamics and gene expression responses to bacterial infection.
Topics: Aeromonas salmonicida; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Citrulline; Diet; Dietary Supplements; Gene Expression Regulation; Gram-Negative Bacterial Infections; Oncorhynchus mykiss; Ornithine | 2020 |
Acute effects of Nitrosigine® and citrulline malate on vasodilation in young adults
Topics: Adolescent; Adult; Arginine; Citrulline; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Drug Combinations; Female; Healthy Volunteers; Humans; Inositol; Malates; Male; Silicates; Ultrasonography; Vasodilation; Young Adult | 2020 |
Daily watermelon consumption decreases plasma sVCAM-1 levels in overweight and obese postmenopausal women.
Topics: Arginine; Atherosclerosis; Biomarkers; Blood Glucose; Body Composition; Citrulline; Citrullus; Diet; Female; Fruit; Humans; Insulin; Insulin Resistance; Lycopene; Middle Aged; Obesity; Overweight; Plant Extracts; Postmenopause; Vascular Cell Adhesion Molecule-1 | 2020 |
Ruminal microbes of adult sheep do not degrade extracellular l-citrulline.
Topics: Ammonia; Animal Feed; Animals; Arginine; Bacteria; Citrulline; Diet; Dietary Supplements; Female; Glutamic Acid; Glutamine; Ornithine; Proline; Rumen; Sheep; Urea | 2020 |
Pharmacokinetic Parameters of Watermelon (Rind, Flesh, and Seeds) Bioactive Components in Human Plasma: A Pilot Study to Investigate the Relationship to Endothelial Function.
Topics: Adult; Arginine; Citrulline; Citrullus; Endothelial Cells; Female; Fruit; Humans; Male; Obesity; Overweight; Phenols; Pilot Projects; Seeds; Vasodilator Agents; Young Adult | 2020 |
Asymmetric dimethylarginine predicts perioperative cardiovascular complications in patients undergoing medium-to-high risk non-cardiac surgery.
Topics: Arginine; C-Reactive Protein; Citrulline; Humans; Prospective Studies | 2020 |
Contrast-enhanced ultrasound for determining muscular perfusion after oral intake of L-citrulline, L-arginine, and galloylated epicatechines: A study protocol.
Topics: Adolescent; Adult; Arginine; Citrulline; Contrast Media; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Humans; Male; Muscle, Skeletal; Randomized Controlled Trials as Topic; Tea; Ultrasonography; Vasodilation | 2020 |
Metformin has no impact on nitric oxide production in patients with pre-diabetes.
Topics: Adult; Arginine; Citrulline; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Nitric Oxide; Prediabetic State | 2021 |
Eight Days of L-Citrulline or L-Arginine Supplementation Did Not Improve 200-m and 100-m Swimming Time Trials.
Topics: Arginine; Citrulline; Dietary Supplements; Double-Blind Method; Female; Humans; Lactic Acid; Male; Nitric Oxide; Swimming | 2022 |
Short-Term Supplementation of Sodium Nitrate vs. Sodium Chloride Increases Homoarginine Synthesis in Young Men Independent of Exercise.
Topics: Arginine; Citrulline; Creatine; Creatinine; Dietary Supplements; Glutamates; Glutamine; Glycine; Homoarginine; Humans; Lysine; Male; Malondialdehyde; Methyltransferases; Nitrates; Nitrites; Ornithine; Phenylalanine; Sarcosine; Sodium Chloride; Tryptophan; Tyrosine | 2022 |
Obesity- and sex-related metabolism of arginine and nitric oxide in adults.
Topics: Arginine; Chromatography, Liquid; Citrulline; Cross-Sectional Studies; Female; Humans; Inflammation; Male; Middle Aged; Nitric Oxide; Obesity, Morbid; Tandem Mass Spectrometry | 2022 |
Effects of L-Citrulline Supplementation on Endothelial Function and Blood Pressure in Hypertensive Postmenopausal Women.
Topics: Arginine; Blood Pressure; Citrulline; Dietary Supplements; Female; Humans; Hypertension; Nitric Oxide; Postmenopause; Pulse Wave Analysis; Vascular Stiffness | 2022 |
Effects of l-Arginine Plus Vitamin C Supplementation on l-Arginine Metabolism in Adults with Long COVID: Secondary Analysis of a Randomized Clinical Trial.
Topics: Adult; Arginine; Ascorbic Acid; Citrulline; COVID-19; Dietary Supplements; Humans; Nitric Oxide; Ornithine; Post-Acute COVID-19 Syndrome; SARS-CoV-2 | 2023 |
The effects of L-Citrulline and Glutathione on Endurance performance in young adult trained males.
Topics: Adult; Arginine; Capsules; Citrulline; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Glutathione; Humans; Male; Young Adult | 2023 |
Enteral citrulline supplementation versus placebo on SOFA score on day 7 in mechanically ventilated critically ill patients: the IMMUNOCITRE randomized clinical trial.
Topics: Adult; Aged; Arginine; Citrulline; Critical Illness; Dietary Supplements; Female; Humans; Intensive Care Units; Male; Middle Aged; Multiple Organ Failure; Organ Dysfunction Scores; Respiration, Artificial; Sepsis; Shock, Septic | 2023 |
1456 other study(ies) available for citrulline and arginine
| Article | Year |
|---|---|
Validation of automated docking programs for docking and database screening against RNA drug targets.
Topics: Algorithms; Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Databases, Factual; Ligands; Models, Molecular; Nucleic Acid Conformation; Quantitative Structure-Activity Relationship; RNA; RNA, Ribosomal; Software | 2004 |
Arginine metabolism by spiroplasma citri.
Topics: Ammonia; Arginine; Citrulline; Fructose; Glucose; Hydrogen-Ion Concentration; Ornithine; Spiroplasma | 1976 |
Ornithine transcarbamylase from Salmonella typhimurium: purification, subunit composition, kinetic analysis, and immunological cross-reactivity.
Topics: Arginine; Citrulline; Cross Reactions; Hydrogen-Ion Concentration; Kinetics; Molecular Conformation; Molecular Weight; Ornithine Carbamoyltransferase; Salmonella typhimurium | 1977 |
Proceedings: Krebs-Henseleit urea cycle in cultured human diploid fibroblasts.
Topics: Arginase; Arginine; Chromatography, Ion Exchange; Citrulline; Diploidy; Fibroblasts; Humans; Hydrogen-Ion Concentration; Hydrolases; Isoenzymes; Kinetics; Manganese; Mycoplasma; Ornithine; Urea | 1975 |
Amino acids of the Krebs-Henseleit cycle of median and lateral lobes in human benign prostatic hypertrophy.
Topics: Amino Acids; Arginine; Citrulline; Humans; Male; Ornithine; Prostate; Prostatic Hyperplasia; Proteins; Urea | 1978 |
New pathways of nitrogen excretion in inborn errors of urea synthesis.
Topics: Arginine; Argininosuccinate Synthase; Argininosuccinic Aciduria; Citrulline; Dietary Proteins; Hippurates; Humans; Infant; Metabolism, Inborn Errors; Nitrogen; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Phenylacetates; Urea | 1979 |
Arginine catabolism in Aphanocapsa 6308.
Topics: Adenosine Triphosphate; Aerobiosis; Ammonia; Arginase; Arginine; Carbon Dioxide; Citrulline; Cyanobacteria; Hydrolases; Ornithine; Urea; Urease | 1978 |
Arginine biosynthesis in Neisseria gonorrhoeae: enzymes catalyzing the formation of ornithine and citrulline.
Topics: Acetyltransferases; Arginine; Citrulline; Enzyme Repression; Glutamates; Neisseria gonorrhoeae; Ornithine; Ornithine Carbamoyltransferase; Transformation, Bacterial | 1978 |
Compartmental behavior of ornithine in Neurospora crassa.
Topics: Arginine; Biological Transport; Citrulline; Mitochondria; Models, Biological; Neurospora; Neurospora crassa; Ornithine; Polyamines; Proline; Subcellular Fractions | 1976 |
The utilization of ornithine and citrulline by the growing kitten.
Topics: Amino Acids, Essential; Animals; Arginine; Body Weight; Cats; Citrulline; Diet; Female; Male; Ornithine; Specific Pathogen-Free Organisms; Structure-Activity Relationship | 1979 |
Enhanced responsiveness of L-929 cells treated with interferon to arginine starvation.
Topics: Animals; Arginine; Canavanine; Cell Survival; Citrulline; Culture Media; Dactinomycin; Dose-Response Relationship, Drug; Interferons; L Cells; Lethal Dose 50; Mice; Ornithine; Time Factors; Vesicular stomatitis Indiana virus | 1975 |
The effect of arginine deprivation on the cytopathogenic effect and replication of human cytomegalovirus.
Topics: Arginine; Bromodeoxyuridine; Cell Nucleus; Citrulline; Culture Media; Cytomegalovirus; Cytopathogenic Effect, Viral; DNA, Viral; Dose-Response Relationship, Drug; Fibroblasts; Humans; Time Factors; Virus Replication | 1975 |
Arginine, a growth-limiting factor for Eubacterium lentum.
Topics: Adenosine Triphosphate; Anaerobiosis; Arginine; Citrulline; Cytochromes; Eubacterium; Hydrolases; Ornithine; Ornithine Carbamoyltransferase; Phosphotransferases | 1976 |
Increase in arginine and citrulline production by 6-azauracil-resistant mutants of Bacillus subtilis.
Topics: Arginine; Bacillus subtilis; Cell-Free System; Citrulline; Drug Resistance, Microbial; Fermentation; Glutamates; Mutation; Ornithine; Ornithine Carbamoyltransferase; Phosphotransferases; Stereoisomerism; Transaminases; Uracil | 1977 |
l-amino acid oxidases of Proteus rettgeri.
Topics: Amino Acid Oxidoreductases; Amino Acids; Arginine; Carbon Radioisotopes; Cell Fractionation; Cell-Free System; Centrifugation, Density Gradient; Chelating Agents; Citrulline; Deamination; Histidine; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Lysine; Ornithine; Oxygen Consumption; Proteus; Pyruvates; Stereoisomerism | 1975 |
Epiarginasic regulation in Saccharomyces cerevisiae. Citrulline, the third effector, acts at a specific binding site on the ornithine carbamoyltransferase.
Topics: Arginase; Arginine; Binding Sites; Citrulline; Kinetics; Molecular Weight; Ornithine; Ornithine Carbamoyltransferase; Protein Binding; Saccharomyces cerevisiae | 1978 |
[Importance of arginine content and arginase activity in fertility].
Topics: Arginase; Arginine; Citrulline; Guanidines; Humans; Infertility, Male; Male; Semen; Urea | 1979 |
The interrelationship between ureogenesis and protein synthesis in isolated rat-liver cells.
Topics: Amino Acids; Aminooxyacetic Acid; Ammonia; Animals; Arginine; Citrulline; Cycloheximide; Glucose; Leucine; Liver; Male; Protein Biosynthesis; Rats; Urea; Valine | 1979 |
Effect of aging on free amino acids and electrolytes in leg skeletal muscle.
Topics: Aged; Aging; Alanine; Amino Acids; Arginine; Citrulline; Electrolytes; Histidine; Humans; Leg; Male; Middle Aged; Muscles; Water | 1979 |
Urea cycle operation in the arginine deficient rat.
Topics: Ammonia; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Citrulline; Liver; Male; Ornithine; Ornithine Carbamoyltransferase; Orotic Acid; Rats; Urea | 1979 |
Trypanosoma spp., Leishmania spp. and Leptomonas spp.: enzymes of ornithine-arginine metabolism.
Topics: Amidohydrolases; Animals; Arginase; Arginine; Argininosuccinate Lyase; Citrulline; Eukaryota; Hydrolases; Leishmania; Ornithine; Ornithine Carbamoyltransferase; Species Specificity; Trypanosoma | 1978 |
Control of argininosuccinate synthetase by arginine in human lymphoblasts.
Topics: Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Cell Division; Cells, Cultured; Citrulline; Cycloheximide; Humans; Ligases; Lymphocytes | 1978 |
Canavanine-resistant variants of human lymphoblasts.
Topics: Arginine; Arginine-tRNA Ligase; Argininosuccinate Lyase; Argininosuccinate Synthase; Canavanine; Cell Line; Citrulline; Drug Resistance; Genetic Variation; Humans; Lymphocytes; Phenotype | 1978 |
Cyclic forms of the alpha-keto acid analogs of arginine, citrulline, homoarginine, and homocitrulline.
Topics: Arginine; Citrulline; Homoarginine; Imino Acids; Keto Acids; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Oxidation-Reduction; Spectrophotometry; Structure-Activity Relationship | 1978 |
Metabolism of urea cycle intermediates in chronic renal failure.
Topics: Amino Acids; Animals; Arginine; Argininosuccinate Synthase; Citrulline; Guanidines; Kidney; Kidney Failure, Chronic; Ornithine; Ornithine-Oxo-Acid Transaminase; Polyamines; Protein Biosynthesis; Rats; Urea; Uremia | 1978 |
[Citrullinemia and argininosuccinic aciduria].
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Arginine; Argininosuccinate Synthase; Argininosuccinic Acid; Argininosuccinic Aciduria; Citrulline; Humans; Infant; Infant, Newborn; Male | 1978 |
Metabolism of arginine by the isolated perfused rat kidney.
Topics: Acetates; Animals; Arginine; Butyrates; Chromatography, High Pressure Liquid; Citrulline; Creatine; Guanidines; Kidney; Male; Perfusion; Rats; Succinates | 1978 |
Ureotelism and ammonotelism in trypanosomatids.
Topics: Ammonia; Animals; Arginine; Citrulline; Crithidia; Culture Media; Eukaryota; Leishmania; Species Specificity; Trypanosoma; Urea | 1978 |
A simple method for the conversion of arginine to ornithine & citrulline.
Topics: Animals; Arginine; Chemical Phenomena; Chemistry; Citrulline; In Vitro Techniques; Ornithine; Rats | 1978 |
Intracellular compartmentation and transport of metabolites.
Topics: Arginine; Biological Transport; Cell Compartmentation; Citrulline; Cytosol; Intracellular Membranes; Kinetics; Mitochondria; Models, Biological; Neurospora; Ornithine; Ornithine Carbamoyltransferase; Ornithine Decarboxylase; Polyamines | 1978 |
Arginyl-tRNA synthetase from Escherichia coli. Influence of arginine biosynthetic precursors on the charging of arginine-acceptor tRNA with [14C]arginine.
Topics: Amino Acyl-tRNA Synthetases; Arginine; Arginine-tRNA Ligase; Argininosuccinate Lyase; Argininosuccinic Acid; Citrulline; Escherichia coli; Kinetics; Ornithine | 1976 |
Regulation of ornithine transcarbamylase in Rhodotorula glutinis.
Topics: Amino Acids; Arginine; Citrulline; Enzyme Repression; Mitosporic Fungi; Ornithine Carbamoyltransferase; Rhodotorula; Saccharomyces cerevisiae | 1976 |
Neonatal citrllinemia: treatment with keto-analogues of essential amino acids.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Essential; Arginine; Argininosuccinate Synthase; Citrulline; Fibroblasts; Histidine; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Threonine; Tryptophan; Valine | 1977 |
The occurrence and seasonal variation of gigartinine and L-citrullinyl-L-arginine in Chondrus crispus Stackh.
Topics: Amino Acids; Arginine; Citrulline; Dipeptides; Magnetic Resonance Spectroscopy; Ornithine; Rhodophyta; Seasons; Urea | 1977 |
Glucagon secretion induced by natural and artificial amino acids in the perfused rat pancreas.
Topics: Amino Acids; Animals; Arginine; Citrulline; Dose-Response Relationship, Drug; Glucagon; In Vitro Techniques; Male; Ornithine; Pancreas; Rats; Stimulation, Chemical | 1977 |
Urea as a selective inhibitor of argininosuccinate lyase.
Topics: Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Citrulline; Kinetics; Lyases; Mitochondria, Liver; Rats; Urea | 1977 |
Nitrogen metabolism in neonatal citrullinaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Citrulline; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Nitrogen; Ornithine; Urea | 1977 |
Periodic hyperammonemia, hyperlysinemia, and homocitrullinuria associated with decreased argininosuccinate synthetase and arginase activities.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Ammonia; Arginase; Arginine; Argininosuccinate Synthase; Citrulline; Humans; Hyperargininemia; Intellectual Disability; Ligases; Liver; Lysine; Male | 1977 |
[Plasma amino acids in ankylosing spondylitis (author's transl)].
Topics: 2-Aminoadipic Acid; Adult; Age Factors; Amino Acids; Arginine; Citrulline; Humans; Isoleucine; Male; Methylhistidines; Middle Aged; Spondylitis, Ankylosing | 1977 |
The enzymic derivation of citrulline residues from arginine residues in situ during the biosynthesis of hair proteins that are cross-linked by isopeptide bonds.
Topics: Amino Acids; Animals; Arginine; Calcium; Citrulline; Hair; Keratins; Kinetics; Macromolecular Substances; Protein Biosynthesis; Proteins | 1977 |
Cerebrospinal fluid and plasma glutamine elevation by anticonvulsant drugs: a potential diagnostic and therapeutic trap.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Arginine; Child; Child, Preschool; Citrulline; Epilepsy; False Positive Reactions; Female; Glutamine; Humans; Infant; Male; Middle Aged; Ornithine; Phenobarbital; Primidone; Urea | 1976 |
Arginine catabolism by Treponema denticola.
Topics: Arginine; Carbon Dioxide; Citrulline; Hydrolases; Ornithine; Ornithine Carbamoyltransferase; Proline; Treponema | 1976 |
Clinical and biochemical studies on periodic hyperammonemia with hyperlysinemia and homocitrullinuria.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Anorexia; Arginase; Arginine; Citrulline; Erythrocytes; Growth Disorders; Humans; Intellectual Disability; Lysine; Male | 1976 |
Intravenous loading with arginine-hydrochloride and ornithine-aspartate in siblings of two families, presenting a familial neurological syndrome associated with cystinuria.
Topics: Amino Acids; Arginine; Aspartic Acid; Child; Citrulline; Cystinuria; Glutamine; Humans; Hyperargininemia; Lysine; Ornithine | 1976 |
A rapid method for quantitative separation of urea cycle intermediates.
Topics: Animals; Arginine; Chromatography, Ion Exchange; Citrulline; Ornithine; Urea | 1976 |
Accumulation of arginine precursors in Escherichia coli: effects on growth, enzyme repression, and application to the forward selection of arginine auxotrophs.
Topics: Arginine; Argininosuccinate Lyase; Citrulline; Enzyme Repression; Escherichia coli; Lyases; Mutation; Operon; Ornithine; Recombination, Genetic; Species Specificity; Transduction, Genetic | 1975 |
Determination of arginnosuccinate in normal blood serum and liver.
Topics: Animals; Arginine; Carbon Radioisotopes; Citrulline; Liver; Microchemistry; Ninhydrin; Rats; Succinates | 1975 |
Possible effect of blood ammonia on food intake of rats fed amino acid imbalanced diets.
Topics: Amino Acids; Ammonia; Animal Nutritional Physiological Phenomena; Animals; Arginine; Aspartic Acid; Body Weight; Citrulline; Histidine; Ligases; Liver; Male; Nutrition Disorders; Perfusion; Protein Deficiency; Quaternary Ammonium Compounds; Rats; Structure-Activity Relationship; Succinates; Tryptophan | 1975 |
Urinary metabolites characteristic of urea-cycle amino acid deficiency.
Topics: Amino Acids; Amino Acids, Essential; Ammonia; Animal Nutritional Physiological Phenomena; Animals; Arginine; Biotransformation; Body Weight; Carbamyl Phosphate; Citrates; Citrulline; Deficiency Diseases; Diet; Male; Nitrogen; Ornithine; Orotic Acid; Pyrimidines; Rats; Urea | 1975 |
Effects of protein content of diet and cortisol treatment on uptake of arginine by rat liver.
Topics: Animals; Arginine; Caseins; Citrulline; Dietary Proteins; Hydrocortisone; Liver; Male; Perfusion; Proteins; Rats | 1975 |
Citrulline metabolism in normal and citrullinemic human lymphocyte lines.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Argininosuccinate Synthase; Argininosuccinic Acid; Cell Line; Citrulline; Genes; Genetic Variation; Humans; Kinetics; Lymphocytes; Mutation; Urea | 1975 |
Hyperdibasicaminoaciduria, hyperammonemia, and growth retardation: Treatment with arginine, lysine, and citrulline.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Child; Citrulline; Female; Growth Disorders; Humans; Lysine | 1975 |
Metabolism of arginine and ornithine in the cow and rabbit mammary tissue.
Topics: Abdomen; Animals; Arginase; Arginine; Argininosuccinate Lyase; Cattle; Citrulline; Female; Iliac Artery; Mammary Glands, Animal; Milk Proteins; Ornithine; Ornithine Carbamoyltransferase; Pregnancy; Rabbits; Species Specificity; Veins | 1975 |
Constitutive nitric oxide synthase from cerebellum is reversibly inhibited by nitric oxide formed from L-arginine.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebellum; Citrulline; Homeostasis; Kinetics; Male; Methylene Blue; Methylnitronitrosoguanidine; Nitric Oxide; Nitric Oxide Synthase; Oxyhemoglobins; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Vasodilator Agents | 1992 |
Pterins inhibit nitric oxide synthase activity in rat alveolar macrophages.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cells, Cultured; Citrulline; Hypoxanthines; Interferon-gamma; Macrophages, Alveolar; Male; Nitric Oxide Synthase; Nitrites; Pteridines; Pterins; Rats; Rats, Wistar; Recombinant Proteins | 1992 |
L-arginine as an antihypertensive agent.
Topics: Antihypertensive Agents; Arginine; Blood Pressure; Cardiac Output; Citrulline; Cushing Syndrome; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Injections, Intravenous; Nitrates; Nitrites | 1992 |
Interaction of non-arginine compounds with the endothelium-derived relaxing factor inhibitor, NG-monomethyl L-arginine.
Topics: Amiloride; Animals; Aorta; Arginine; Bucladesine; Citrulline; Drug Interactions; In Vitro Techniques; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred Strains; Superoxide Dismutase; Vasodilation; Vasodilator Agents | 1992 |
Immobilization and treatment of Streptococcus faecalis for the continuous conversion of arginine into citrulline.
Topics: Arginine; Bacterial Adhesion; Citrulline; Enterococcus faecalis; Hydrolases; Kinetics | 1990 |
Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Granulocytes; Kainic Acid; N-Methylaspartate; Nitric Oxide Synthase; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
Ca2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding, Competitive; Biopterins; Brain; Calcium; Calmodulin; Citrulline; Hydrogen Peroxide; NADP; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Swine | 1992 |
In vitro interaction between cerebellar astrocytes and granule cells: a putative role for nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Astrocytes; Calcimycin; Cell Communication; Cells, Cultured; Cerebellum; Citrulline; Cyclic GMP; Kinetics; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats | 1992 |
Induction of nitric oxide synthase is a necessary precondition for expression of tumor necrosis factor-independent tumoricidal activity by activated macrophages.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bone Marrow; Cell Line; Cell Survival; Cells, Cultured; Citrulline; Drug Resistance; Enterococcus faecalis; Escherichia coli; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mast-Cell Sarcoma; Moraxella catarrhalis; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Onium Compounds; Peptidoglycan; Phagocytes; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha | 1992 |
Nitric oxide synthase from cerebellum catalyzes the formation of equimolar quantities of nitric oxide and citrulline from L-arginine.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebellum; Citrulline; Kinetics; Luminescent Measurements; Male; Nitric Oxide; Nitric Oxide Synthase; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Tritium | 1992 |
Biosynthesis of nitric oxide and citrulline from L-arginine by constitutive nitric oxide synthase present in rabbit corpus cavernosum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Kinetics; Male; Nitric Oxide; Nitric Oxide Synthase; Penis; Rabbits; Subcellular Fractions | 1992 |
Identification and characterization of a calmodulin-dependent nitric oxide synthase from GH3 pituitary cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Autoradiography; Biopterins; Blotting, Western; Brain; Calmodulin; Cattle; Cells, Cultured; Chromatography, DEAE-Cellulose; Citrulline; Enzyme Activation; Kinetics; NADH Dehydrogenase; Nitric Oxide Synthase; Nitroarginine; Nitroblue Tetrazolium; omega-N-Methylarginine; Pituitary Gland | 1992 |
Nitric oxide synthase is a cytochrome P-450 type hemoprotein.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Carbon Monoxide; Cerebellum; Citrulline; Cytochrome P-450 Enzyme System; Hemeproteins; Hydroxylation; Kinetics; Macrophages; Mice; Nitric Oxide Synthase; Spectrophotometry | 1992 |
Effects of interferon-gamma on nitric oxide synthase activity and endothelin-1 production by vascular endothelial cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cattle; Cells, Cultured; Citrulline; Endothelins; Endothelium, Vascular; Interferon-gamma; Nitric Oxide Synthase; Tumor Necrosis Factor-alpha | 1992 |
Early loss of the tyrosyl radical in ribonucleotide reductase of adenocarcinoma cells producing nitric oxide.
Topics: Adenocarcinoma; Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Western; Citrulline; Electron Spin Resonance Spectroscopy; Enzyme Induction; Free Radicals; Kinetics; Mammary Neoplasms, Experimental; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Ribonucleotide Reductases; Tumor Cells, Cultured; Tyrosine | 1992 |
[The dibasic amino acid metabolic disorders].
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Blood Transfusion; Citrulline; Humans; Hyperargininemia; Ornithine; Ornithine Carbamoyltransferase Deficiency Disease; Renal Dialysis | 1992 |
Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis.
Topics: Acetylcholine; Animals; Aorta; Arginine; Arteriosclerosis; Calcimycin; Cholesterol; Citrulline; Estrogens; Female; In Vitro Techniques; Male; Nitric Oxide; Nitroglycerin; Ovariectomy; Rabbits; Sex Factors; Triglycerides | 1992 |
Cytochrome P450 catalyzes the oxidation of N omega-hydroxy-L-arginine by NADPH and O2 to nitric oxide and citrulline.
Topics: Animals; Arginine; Carbon Monoxide; Catalysis; Citrulline; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Male; Miconazole; Microsomes, Liver; NADP; Nitric Oxide; Oxidation-Reduction; Oxygen; Rats; Rats, Inbred Strains | 1992 |
Net renal arginine flux in rats is not affected by dietary arginine or dietary protein intake.
Topics: Animals; Arginine; Body Weight; Citrulline; Diet; Dietary Proteins; Hemodynamics; Kidney; Male; Rats; Rats, Inbred Strains | 1992 |
Formation of nitrogen oxides and citrulline upon oxidation of N omega-hydroxy-L-arginine by hemeproteins.
Topics: Animals; Arginine; Citrulline; Cytochrome P-450 Enzyme System; Dexamethasone; Hemeproteins; Horseradish Peroxidase; Kinetics; Male; Miconazole; Microsomes, Liver; Nitrogen Oxides; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1992 |
Roles of arginine in growth of Clostridium botulinum Okra B.
Topics: Arginine; Botulinum Toxins; Citrulline; Clostridium botulinum; Proline | 1992 |
Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.
Topics: Animals; Arginine; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Dizocilpine Maleate; Fetus; Glutamates; Hemoglobins; Hippocampus; Kinetics; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase | 1991 |
Nitric oxide synthesis in endothelial cells: evidence for a pathway inducible by TNF-alpha.
Topics: Animals; Aorta; Arginine; Citrulline; Cyclic GMP; Endothelium, Vascular; Glomerular Mesangium; Lipopolysaccharides; Nitric Oxide; Renal Artery; Tumor Necrosis Factor-alpha | 1991 |
L-arginine abrogates salt-sensitive hypertension in Dahl/Rapp rats.
Topics: Animals; Arginine; Blood Pressure; Citrulline; Cyclic GMP; Glomerular Filtration Rate; Hypertension; Nitric Oxide; omega-N-Methylarginine; Rats; Sodium Chloride | 1991 |
L-citrulline production from L-arginine by macrophage nitric oxide synthase. The ureido oxygen derives from dioxygen.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Citrulline; Cytosol; Gas Chromatography-Mass Spectrometry; Interferon-gamma; Lipopolysaccharides; Macrophages; Mass Spectrometry; Nitric Oxide Synthase; Oxygen; Oxygen Isotopes | 1990 |
Metabolic and secretory response of parotid cells to cationic amino acids. Uptake and catabolism of L-arginine and L-ornithine.
Topics: Amylases; Animals; Arginine; Citrulline; Female; Glutamates; Glutamic Acid; Ketoglutaric Acids; NADP; Ornithine; Oxidation-Reduction; Parotid Gland; Rats; Transglutaminases; Urea | 1991 |
The preparation of antibodies reactive against citrulline-containing charge isomers of myelin basic protein but not against the arginine-containing charge isomers.
Topics: Amino Acid Sequence; Antibodies; Antibody Specificity; Arginine; Calorimetry, Differential Scanning; Chromatography, Thin Layer; Citrulline; Humans; Isomerism; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Myelin Basic Protein; Spectrometry, Mass, Fast Atom Bombardment | 1990 |
Brain nitric oxide synthase is a biopterin- and flavin-containing multi-functional oxido-reductase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Calcium; Calmodulin; Cerebellum; Citrulline; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Hydrogen Peroxide; Kinetics; NADP; Nitric Oxide; Nitric Oxide Synthase; Spectrophotometry; Swine | 1991 |
Characterization of nitric oxide synthases in non-adrenergic non-cholinergic nerve containing tissue from the rat anococcygeus muscle.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Calcium; Citrulline; Endothelium, Vascular; In Vitro Techniques; Male; Muscles; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Inbred Strains; Vas Deferens | 1991 |
Macrophages can convert citrulline into arginine.
Topics: Animals; Arginine; Carbon Radioisotopes; Cells, Cultured; Citrulline; Kinetics; Lipopolysaccharides; Macrophages; Male; Nitrates; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains | 1992 |
Basolateral uptake and tubular metabolism of L-citrulline in the isolated-perfused non-filtering kidney of the African clawed toad (Xenopus laevis).
Topics: Amino Acids; Animals; Arginine; Citrulline; Kidney Tubules; Kinetics; Male; Ornithine; Perfusion; Xenopus laevis | 1991 |
N-acetylglutamate synthetase deficiency: clinical and laboratory observations.
Topics: Acetyltransferases; Amino-Acid N-Acetyltransferase; Ammonia; Arginine; Benzoates; Benzoic Acid; Citrulline; Dietary Proteins; Humans; Infant; Infant, Newborn; Liver; Male; Phenylacetates | 1991 |
Hyperornithinemia, hyperammonemia and homocitrullinuria--a case report and study of ornithine metabolism using in vivo deuterium labelling.
Topics: Adult; Ammonia; Arginine; Chromatography, Liquid; Citrulline; Deuterium; Humans; Male; Mass Spectrometry; Ornithine | 1991 |
Isolation and characterization of Pseudomonas putida mutants affected in arginine, ornithine and citrulline catabolism: function of the arginine oxidase and arginine succinyltransferase pathways.
Topics: Acyltransferases; Amino Acid Oxidoreductases; Ammonia-Lyases; Arginine; Citrulline; Mutation; Ornithine; Pseudomonas putida | 1991 |
Citrulline concentrations in human plasma after arginine load.
Topics: Adult; Amino Acids, Essential; Arginine; Argininosuccinate Synthase; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Citrulline; Humans; Male; Ornithine; Ornithine Carbamoyltransferase Deficiency Disease | 1991 |
Dietary arginine supplementation does not enhance lymphocyte proliferation or interleukin-2 production in young and aged rats.
Topics: Aging; Alanine; Animals; Arginine; Body Weight; Citrulline; Concanavalin A; Diet; Glutamine; Interleukin-2; Lymphocyte Activation; Male; Organ Size; Ornithine; Phytohemagglutinins; Pokeweed Mitogens; Rats; Rats, Inbred F344; Spleen | 1991 |
Selective induction of metabolic activation programs in peritoneal macrophages by lipopolysaccharide substructures.
Topics: Animals; Arginine; Carbohydrate Sequence; Cells, Cultured; Citrulline; Dinoprostone; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Molecular Sequence Data; Ornithine; Peritoneum; Salmonella typhimurium | 1991 |
Concentrations of amino acids in the plasma of neonatal foals with septicemia.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Arginine; Citrulline; Female; Glycine; Gram-Negative Bacteria; Horse Diseases; Horses; Immunoglobulin G; Isoleucine; Male; Phenylalanine; Proline; Sepsis; Threonine; Valine | 1991 |
Production of citrulline and ornithine by interferon-gamma treated macrophages.
Topics: Animals; Arginase; Arginine; Citrulline; Enzyme Induction; Glycolipids; Hydrolases; Interferon-gamma; Lipid A; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C3H; Ornithine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1991 |
Stimulation of L-ornithine uptake and L-citrulline and urea biosynthesis by D-arginine.
Topics: Adenosine Triphosphate; Animals; Arginine; Citrulline; Edetic Acid; Liver; Male; Mitochondria, Liver; Ornithine; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Urea | 1991 |
Effect of arginine depletion on glomerular and tubular kidney function: studies in isolated perfused rat kidneys.
Topics: Animals; Arginine; Body Water; Citrulline; Glomerular Filtration Rate; Glucose; In Vitro Techniques; Kidney; Kidney Glomerulus; Kidney Tubules; Male; omega-N-Methylarginine; Ornithine; Perfusion; Rats; Rats, Inbred Strains; Sodium; Time Factors; Urine | 1991 |
Renal arginine synthesis: studies in vitro and in vivo.
Topics: Alanine; Ammonium Chloride; Animals; Arginine; Aspartic Acid; Citrulline; Glomerular Filtration Rate; Glutamates; Glutamic Acid; Glutamine; Glycine; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Kinetics; Male; Rats; Rats, Inbred Strains; Serine | 1990 |
The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: L-glutamine inhibits the generation of L-arginine by cultured endothelial cells.
Topics: Animals; Aorta; Arginine; Argininosuccinic Acid; Cattle; Cell Line; Cells, Cultured; Citrulline; Endothelium, Vascular; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Mice; Muscle, Smooth, Vascular; Nitric Oxide; Rabbits | 1990 |
Correction of ornithine transcarbamylase (OTC) deficiency in spf-ash mice by introduction of rat OTC gene.
Topics: Animals; Arginine; Citrulline; Intestine, Small; Liver; Mice; Mice, Mutant Strains; Mice, Transgenic; Ornithine Decarboxylase; Rats | 1991 |
High-performance liquid chromatographic analysis of the unusual pathway of oxidation of L-arginine to citrulline and nitric oxide in mammalian cells.
Topics: Adenocarcinoma; Animals; Arginine; Cell Line; Chromatography, High Pressure Liquid; Citrulline; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Nitric Oxide; Oxidation-Reduction | 1991 |
Arginine metabolism in rat enterocytes.
Topics: Animals; Arginine; Citrulline; Female; Intestinal Mucosa; Ornithine; Oxidation-Reduction; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Urea | 1991 |
Stimulation by D-glucose of the direct conversion of arginine to citrulline in enterocytes isolated from pig jejunum.
Topics: Animals; Arginine; Carbon Radioisotopes; Citrulline; Glucose; In Vitro Techniques; Intestinal Mucosa; Jejunum; Swine; Urea | 1991 |
Nitrogen metabolism and somatotropin secretion in lambs receiving arginine and ornithine via abomasal infusion.
Topics: Amino Acids; Animals; Arginine; Blood Urea Nitrogen; Citrulline; Dietary Proteins; Enteral Nutrition; Growth Hormone; Least-Squares Analysis; Male; Nitrogen; Ornithine; Random Allocation; Sheep; Urea | 1990 |
Inherited hyperactivation of L-arginine synthesis in gamma + B lymphocytes of systemic autoimmune MRL mice.
Topics: Animals; Arginine; Autoantibodies; Autoimmune Diseases; B-Lymphocytes; Citrulline; Female; Immunoglobulin gamma-Chains; In Vitro Techniques; Lymphocyte Activation; Mice; Mice, Mutant Strains; Urea | 1990 |
Alloantigen-induced activation of rat splenocytes is regulated by the oxidative metabolism of L-arginine.
Topics: Animals; Arginine; Citrulline; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Immune Tolerance; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Macrophages; Mice; Nitrates; omega-N-Methylarginine; Phytohemagglutinins; Rats; T-Lymphocytes; T-Lymphocytes, Cytotoxic | 1990 |
EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages.
Topics: Animals; Arginine; Cells, Cultured; Citrulline; Electron Spin Resonance Spectroscopy; Female; Iron; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Mycobacterium bovis; Nitrogen; Nitrogen Oxides; omega-N-Methylarginine; Sulfur; Tuberculosis | 1990 |
The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: cultured endothelial cells recycle L-citrulline to L-arginine.
Topics: Animals; Aorta; Arginine; Cattle; Cell Line; Cells, Cultured; Citrulline; Endothelium, Vascular; Kinetics; Mice; Muscle, Smooth, Vascular; Nitric Oxide; Organ Culture Techniques; Urea | 1990 |
Arginine catabolism by strains of oral streptococci.
Topics: Arginine; Cell Wall; Citrulline; Cytoplasm; Humans; Hydrolases; Ornithine; Ornithine Carbamoyltransferase; Saliva; Streptococcus; Streptococcus sanguis; Temperature | 1990 |
Localization of arginine synthesis along rat nephron.
Topics: Animals; Arginine; Citrulline; Kidney Tubules, Proximal; Male; Nephrons; Osmolar Concentration; Rats; Rats, Inbred Strains; Time Factors; Urea | 1990 |
Effect of level of dietary protein on arginine-stimulated citrulline synthesis. Correlation with mitochondrial N-acetylglutamate concentrations.
Topics: Animals; Arginine; Citrulline; Dietary Proteins; Glutamates; Kinetics; Male; Mitochondria, Liver; Rats; Rats, Inbred Strains | 1990 |
L-arginine and arginine analogues: effects on isolated blood vessels and cultured endothelial cells.
Topics: Animals; Arginine; Cattle; Citrulline; Endothelium, Vascular; Guanethidine; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Ornithine; Rabbits; Rats; Rats, Inbred Strains; Stereoisomerism; Swine | 1990 |
Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine.
Topics: Animals; Arginine; Citrulline; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Nitrates; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Toxoplasma | 1990 |
Endothelial cells metabolize NG-monomethyl-L-arginine to L-citrulline and subsequently to L-arginine.
Topics: Acetylcholine; Animals; Aorta; Aorta, Thoracic; Arginine; Cattle; Cells, Cultured; Citrulline; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Rabbits | 1990 |
Temporal expression of different pathways of 1-arginine metabolism in healing wounds.
Topics: Animals; Arginase; Arginine; Cells, Cultured; Citrulline; Hydrolases; In Vitro Techniques; Macrophages; Male; Neutrophils; Nitrites; Ornithine; Rats; Urea; Wound Healing | 1990 |
Regulation of growth and polyamine biosynthesis of the ciliated protozoan Tetrahymena thermophila. Effects of L-arginine metabolites and polyamines.
Topics: Animals; Arginine; Biogenic Polyamines; Citrulline; Enzyme Activation; Hydrolases; Ornithine; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Tetrahymena; Transaminases | 1990 |
Potential antitumour agents. Synthesis, DNA binding studies and biological activity of 9-aminoacridinyl derivatives of citrulline and arginine.
Topics: Aminacrine; Aminoacridines; Antineoplastic Agents; Arginine; Cell Cycle; Citrulline; DNA; Leukemia, Experimental; Tumor Cells, Cultured | 1990 |
Citrate therapy in argininosuccinate lyase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Argininosuccinic Acid; Argininosuccinic Aciduria; Aspartic Acid; Child; Citrates; Citric Acid; Citrulline; Female; Humans; Infant; Lyases | 1990 |
Peptidylarginine deiminase in rat and mouse hemopoietic cells.
Topics: Ammonia; Animals; Arginine; Blotting, Western; Bone Marrow; Bone Marrow Cells; Citrulline; Female; Hydrolases; Immunosorbent Techniques; Macrophages; Mice; Mice, Inbred C57BL; Monocytes; Neutrophils; Peritoneal Cavity; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Rats; Rats, Inbred Strains; Spleen | 1990 |
Homocitrullinuria and homoargininuria in hyperargininaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Child; Child, Preschool; Citrulline; Homoarginine; Humans; Lysine; Male | 1988 |
Homocitrullinuria and homoargininuria in lysinuric protein intolerance.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Arginine; Child; Citrulline; Female; Homoarginine; Humans; Kidney; Lysine; Male; Ornithine | 1989 |
Antiproliferative activity of gamma-interferon combined with lipopolysaccharide on murine adenocarcinoma: dependence on an L-arginine metabolism with production of nitrite and citrulline.
Topics: Adenocarcinoma; Animals; Arginine; Cell Division; Citrulline; Interferon-gamma; Kinetics; Lipopolysaccharides; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Nitrites; Recombinant Proteins; Tumor Cells, Cultured | 1989 |
The specificity of two proteinases that cleave adjacent to arginine, C1 esterase and acrosin, for peptide p-nitroanilide substrates.
Topics: Acrosin; Anilides; Arginine; Binding Sites; Citrulline; Complement Activating Enzymes; Complement C1s; Humans; In Vitro Techniques; Kinetics; Lysine; Peptides; Serine Endopeptidases; Substrate Specificity | 1989 |
Biochemical and genetic studies with arginine and proline auxotrophs of Neisseria gonorrhoeae.
Topics: Acetyltransferases; Amino-Acid N-Acetyltransferase; Arginine; Argininosuccinate Synthase; Carbon-Nitrogen Ligases; Citrulline; Genetic Complementation Test; Humans; Ligases; Neisseria gonorrhoeae; Ornithine Carbamoyltransferase; Proline; Transformation, Bacterial; Uracil | 1989 |
Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.
Topics: Animals; Arginine; Brain; Citrulline; Cyclic GMP; Cytosol; Guanylate Cyclase; Kinetics; Male; Nitric Oxide; Rats; Signal Transduction; Synaptosomes | 1989 |
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.
Topics: Animals; Arginine; Aspartic Acid; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quisqualic Acid; Rats | 1989 |
Citrullinemia: early diagnosis & successful management of an otherwise lethal disorder.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Argininosuccinate Synthase; Citrulline; Female; Humans; India; Infant, Newborn | 1989 |
Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate. Tetrahydrobiopterin is required as a cofactor.
Topics: Animals; Arginine; Biopterins; Cell Line; Chromatography, High Pressure Liquid; Citrulline; Cytosol; Kinetics; Macrophages; NADP; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction | 1989 |
Kupffer cell cytotoxicity to hepatocytes in coculture requires L-arginine.
Topics: Animals; Arginine; Aspartate Aminotransferases; Cell Survival; Cells, Cultured; Citrulline; Infections; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitrates; Nitrites; omega-N-Methylarginine; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1989 |
The guanosine binding site of the Tetrahymena ribozyme.
Topics: Animals; Arginine; Base Sequence; Citrulline; Exons; Guanosine; Introns; Molecular Sequence Data; Mutation; RNA Precursors; RNA Splicing; RNA, Catalytic; RNA, Ribosomal; Tetrahymena | 1989 |
[Carbamyl phosphate synthase deficiency: clinical symptoms, diagnosis and dietary-medicamentous treatment in the neonatal period and infancy].
Topics: Amino Acids; Ammonia; Arginine; Benzoates; Benzoic Acid; Carbamoyl-Phosphate Synthase (Ammonia); Carnitine; Citrulline; Combined Modality Therapy; Dietary Proteins; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Male; Pregnancy | 1989 |
Evidence that activation of Kupffer cells results in production of L-arginine metabolites that release cell-associated iron and inhibit hepatocyte protein synthesis.
Topics: Animals; Arginine; Citrulline; Culture Media; Iron; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitrates; Nitrites; Protein Biosynthesis; Proteins; Rats | 1989 |
Orotic aciduria due to arginine deprivation: changes in the levels of carbamoyl phosphate and of other urea cycle intermediates in mouse liver.
Topics: Animals; Arginine; Body Weight; Carbamates; Carbamyl Phosphate; Citrulline; Diet; Glutamates; Liver; Male; Mice; Mice, Inbred Strains; Ornithine; Orotic Acid | 1989 |
Detection of kinetically abnormal argininosuccinate synthase in neonatal citrullinemia by conversion of citrulline to arginine in intact fibroblasts.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Argininosuccinate Synthase; Cells, Cultured; Child, Preschool; Citrulline; Fibroblasts; Humans; Infant, Newborn; Kinetics; Ligases; Mutation; Skin | 1989 |
Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst.
Topics: Arginine; Citrulline; Humans; Hydrogen Peroxide; Macrophage Activation; Macrophages; Morpholines; Nitrates; Nitrites; Nitrosamines; Superoxides | 1987 |
Superoxide-induced deimination of arginine in hematopoietic cells.
Topics: Animals; Arginine; Bone Marrow; Citrulline; Hematopoietic Stem Cells; Imines; Mice; Superoxides | 1988 |
Submitochondrial localization of arginase and other enzymes associated with urea synthesis and nitrogen metabolism, in liver of Squalus acanthias.
Topics: Animals; Arginase; Arginine; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Fractionation; Citrulline; Dogfish; Glutamate-Ammonia Ligase; Kinetics; Microscopy, Electron; Mitochondria, Liver; Nitrogen; Ornithine; Ornithine Carbamoyltransferase; Submitochondrial Particles; Urea | 1985 |
A novel citrulline-forming enzyme implicated in the formation of nitric oxide by vascular endothelial cells.
Topics: Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Citrulline; Endothelium, Vascular; Nitric Oxide; Swine | 1989 |
An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro.
Topics: Animals; Arginine; Citrulline; In Vitro Techniques; Kupffer Cells; Lipopolysaccharides; Liver; Nitrates; Nitrites; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1989 |
Arginine-specific carbamoyl phosphate metabolism in mitochondria of Neurospora crassa. Channeling and control by arginine.
Topics: Arginine; Carbamates; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carbamyl Phosphate; Citrulline; Feedback; Mitochondria; Mutation; Neurospora; Neurospora crassa; Ornithine; Ornithine Carbamoyltransferase | 1987 |
Carboxypeptidase activity in human mycoplasmas.
Topics: Adenosine Triphosphate; Ammonia; Arginine; Carboxypeptidases; Citrulline; Humans; Lysine Carboxypeptidase; Mycoplasma; Mycoplasma pneumoniae | 1986 |
Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome: low creatine excretion and effect of citrulline, arginine, or ornithine supplement.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Child, Preschool; Citrulline; Creatine; Female; Humans; Lysine; Male; Ornithine; Orotic Acid; Syndrome | 1987 |
Regulation of arginine-ornithine exchange and the arginine deiminase pathway in Streptococcus lactis.
Topics: Adenine Nucleotides; Arginine; Biological Transport, Active; Citrulline; Hydrogen-Ion Concentration; Hydrolases; Ionophores; Lactococcus lactis; Ornithine | 1987 |
Lethal ornithine transcarbamylase deficiency in a female neonate.
Topics: Ammonia; Arginine; Citrulline; Coma; Female; Humans; Infant, Newborn; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Peritoneal Dialysis; Stevens-Johnson Syndrome | 1987 |
Increased urinary excretion of putrescine in hyperargininaemia.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Arginine; Child; Child, Preschool; Citrulline; Cystinuria; Humans; Male; Ornithine; Putrescine | 1987 |
Catabolism of arginine, citrulline and ornithine by Pseudomonas and related bacteria.
Topics: Acyltransferases; Aeromonas; Ammonia-Lyases; Arginine; Citrulline; Klebsiella pneumoniae; Ornithine; Pseudomonas; Pseudomonas aeruginosa; Pseudomonas fluorescens; Succinates | 1987 |
Vascular endothelial cells synthesize nitric oxide from L-arginine.
Topics: Animals; Aorta; Arginine; Bradykinin; Calcimycin; Cells, Cultured; Citrulline; Endothelium, Vascular; Isomerism; Kinetics; Luminescent Measurements; Nitric Oxide; Swine | 1988 |
Serum arginine level in neonatal citrullinaemia.
Topics: Ammonia; Arginine; Citrulline; Humans; Infant, Newborn | 1988 |
Cytokines induce an L-arginine-dependent effector system in nonmacrophage cells.
Topics: Animals; Arginine; Biological Products; Citrulline; Cytokines; Humans; Lipopolysaccharides; Mammary Neoplasms, Experimental; Nitrates; Nitrites; Tumor Cells, Cultured; Urea | 1988 |
Arginine metabolism in wounds.
Topics: Amino Acids; Animals; Arginase; Arginine; Carbon Radioisotopes; Carrageenan; Citrulline; Hydrolases; Macrophages; Male; Muscles; Rats; Rats, Inbred F344; Urea; Wounds and Injuries | 1988 |
Studies on the increase in serum concentrations of urea cycle amino acids among subjects exposed to cadmium.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Arginine; Cadmium Poisoning; Citrulline; Female; Humans; Kidney Diseases; Male; Middle Aged; Ornithine | 1988 |
Determination of agmatine, arginine, citrulline and ornithine by reversed-phase liquid chromatography using automated pre-column derivatization with o-phthalaldehyde.
Topics: Agmatine; Arginine; Autoanalysis; Buffers; Chromatography, Liquid; Citrulline; Guanidines; Homocysteine; Indicators and Reagents; o-Phthalaldehyde; Ornithine | 1988 |
Regulation of sinefungin biosynthesis by the wild-type strain and mutants of Streptomyces incarnatus.
Topics: Adenosine; Adenosine Triphosphate; Antifungal Agents; Arginine; Citrulline; Mutation; Ornithine; Streptomyces; Uridine | 1988 |
Clinical, biochemical and ultrastructural study on the pathogenesis of hyperornithinemia-hyperammonemia-homocitrullinuria syndrome.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Brain; Child; Citrulline; Endoplasmic Reticulum; Humans; Liver Glycogen; Male; Mitochondria, Liver; Ornithine; Tomography, X-Ray Computed | 1988 |
Arginine catabolism in Lactobacillus sake isolated from meat.
Topics: Animals; Arginine; Cattle; Citrulline; Culture Media; Food Microbiology; Glucose; Hydrolases; Hydrolysis; Lactobacillus; Meat; Ornithine; Ornithine Carbamoyltransferase | 1987 |
Increased urinary excretion of argininosuccinate in type II citrullinemia.
Topics: Administration, Oral; Adult; Amino Acid Metabolism, Inborn Errors; Arginine; Argininosuccinate Synthase; Argininosuccinic Acid; Citrulline; Female; Humans; Infant; Infant, Newborn; Kidney; Male | 1987 |
Molecular basis of enzyme abnormalities in urea cycle disorders. With special reference to citrullinemia and argininosuccinic aciduria.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Argininosuccinic Acid; Citrulline; Cloning, Molecular; DNA; Enzyme-Linked Immunosorbent Assay; RNA, Messenger; Urea | 1987 |
Accumulation of D-arginine by rat liver mitochondria.
Topics: Amino Acids; Animals; Arginine; Citrulline; Intracellular Membranes; Male; Membrane Potentials; Mitochondria, Liver; Osmotic Pressure; Oxygen Consumption; Permeability; Rats; Rats, Inbred Strains | 1987 |
Polyamine metabolism in Acanthamoeba: polyamine content and synthesis of ornithine, putrescine, and diaminopropane.
Topics: Acanthamoeba; Animals; Arginase; Arginine; Citrulline; Diamines; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Urease | 1987 |
Urea cycle metabolism: effects of supplemental ornithine or citrulline on performance, tissue amino acid concentrations and enzymatic activity in young pigs fed arginine-deficient diets.
Topics: Animals; Arginase; Arginine; Body Weight; Brain; Citrulline; Intestinal Mucosa; Kidney; Liver; Male; Muscles; Ornithine; Ornithine Carbamoyltransferase; Proline; Swine; Urea | 1987 |
Conversion of peanut trypsin-chymotrypsin inhibitor B-III to a chymotrypsin inhibitor by deimination of the P1 arginine residues in two reactive sites.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Chymotrypsin; Citrulline; Electrophoresis, Polyacrylamide Gel; Hydrolases; Molecular Sequence Data; Plant Proteins; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Structure-Activity Relationship; Substrate Specificity; Trypsin Inhibitors | 1987 |
Occurrence of a new enzyme catalyzing the direct conversion of NG,NG-dimethyl-L-arginine to L-citrulline in rats.
Topics: Amidohydrolases; Animals; Arginine; Citrulline; Female; Hydrolases; Kidney; Mass Spectrometry; Rats; Rats, Inbred Strains | 1987 |
Rapid detection of argininosuccinic aciduria and citrullinuria by fast atom bombardment and tandem mass spectrometry.
Topics: Arginine; Argininosuccinate Synthase; Argininosuccinic Acid; Argininosuccinic Aciduria; Child; Citrulline; Humans; Ligases; Lyases; Mass Spectrometry | 1986 |
Development of arginine-synthesizing enzymes in mouse intestine.
Topics: Animals; Animals, Newborn; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbamoyl-Phosphate Synthase (Ammonia); Citrulline; Intestines; Jejunum; Kidney; Ligases; Lyases; Mice; Mice, Inbred C57BL; Urea | 1986 |
[Effects of canavanine, arginine, ornithine and citrulline on lactate production by oral microorganisms].
Topics: Arginine; Canavanine; Citrulline; Humans; Lactates; Lactobacillus; Ornithine; Streptococcus | 1985 |
Lysinuric protein intolerance presenting as childhood osteoporosis. Clinical and skeletal response to citrulline therapy.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Bone Development; Child, Preschool; Citrulline; Female; Humans; Lysine; Osteogenesis; Osteoporosis | 1985 |
Neonatal citrullinemia associated with cutaneous manifestations and arginine deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Argininosuccinate Synthase; Biopsy; Citric Acid Cycle; Citrulline; Epidermis; Erythema; Humans; Infant; Infant, Newborn; Ligases; Male; Neutrophils; Parakeratosis; Skin Diseases | 1986 |
Metabolic role of urea cycle intermediates: nutritional and clinical aspects. Introduction.
Topics: Ammonia; Animals; Arginine; Body Weight; Citrulline; Intestine, Small; Kidney; Liver; Nutritional Physiological Phenomena; Ornithine; Proline; Rats; Urea | 1985 |
Nutritional and metabolic responses to arginine deficiency in carnivores.
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Arginine; Carnivora; Cats; Citrulline; Dogs; Glutamine; Intestinal Mucosa; Kidney; Liver; Muscles; Nutritional Requirements; Ornithine; Ornithine-Oxo-Acid Transaminase; Orotic Acid; Rats; Species Specificity; Urea | 1985 |
JTC-11 cells derived from Ehrlich ascites tumor deficient in a growing medium containing citrulline.
Topics: Animals; Arginine; Carcinoma, Ehrlich Tumor; Cell Division; Cell Line; Citrulline; Culture Media; DNA, Neoplasm; HeLa Cells; Humans; In Vitro Techniques; L Cells; Mice | 1985 |
Inhibition of intestinal citrulline synthesis causes severe growth retardation in rats.
Topics: Animals; Arginine; Citrulline; Growth Disorders; Growth Inhibitors; Intestinal Mucosa; Intestines; Liver; Male; Oligopeptides; Ornithine; Ornithine Carbamoyltransferase; Rats; Rats, Inbred Strains | 1985 |
[Regulation of synthesis of the capsular antigen of Pasteurella pestis by components of the nutrient medium].
Topics: Antigens, Bacterial; Arginine; Citrulline; Culture Media; Epitopes; Glucose; Glycine; Temperature; Yersinia pestis | 1973 |
[The allosteric origin of the functional irreversibility of an ornithine carbamolytransferase].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Arginine; Citrulline; Ornithine; Ornithine Carbamoyltransferase; Phosphates; Pseudomonas | 1967 |
[Study of the action of genes suppressing uracil requirement in Coprinus radiatus].
Topics: Arginine; Chromosome Mapping; Citrulline; Fungi; Ornithine; Uracil | 1966 |
[Evaluation of the therapeutic possibilities offered by the combination: substrates of the Krebs-Henseleit cycle and vitamins in hepatic toxicoses].
Topics: Adult; Aged; Arginine; Chemical and Drug Induced Liver Injury; Citrulline; Female; Folic Acid; Humans; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[On a combination of amino acids and vitamins in the treatment of liver diseases].
Topics: Adult; Aged; Arginine; Citrulline; Folic Acid; Humans; Liver Diseases; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Clinical observations on the therapeutic efficiency of the combination: arginine HCl, citrulline, ornithine HCl, vitamin B-12, folic acid and nicotinamide in liver diseases and in anemic deficiency syndromes].
Topics: Adult; Aged; Arginine; Citrulline; Folic Acid; Humans; Liver Diseases; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[On the therapeutic value of some amino acids in combination with vitamin B 12, folic acid and nicotinamide in the therapy of hepatic insufficiency].
Topics: Adolescent; Adult; Aged; Arginine; Biliary Tract Diseases; Citrulline; Female; Folic Acid; Humans; Liver Diseases; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Study on the behavior of the bromophthalein test in a group of patients affected by the hepatitis virus, treated with a combination of some amino acids, nicotinamide, folic acid and vitamin B-12].
Topics: Adolescent; Adult; Arginine; Citrulline; Female; Folic Acid; Hepatitis A; Humans; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Clinico-experimental findings on the use of a new liver protective agent].
Topics: Adult; Aged; Arginine; Citrulline; Female; Folic Acid; Hepatitis; Humans; Liver Cirrhosis; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Clinical experimentation with a new pharmacologic combination having a liver protective and detoxicant scope].
Topics: Arginine; Citrulline; Female; Folic Acid; Humans; Liver Diseases; Male; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Clinical cases on the use of a combination of substances with hepatoprotective and detoxicant action in the treatment of some acute and chronic liver diseases].
Topics: Adolescent; Adult; Aged; Arginine; Child; Citrulline; Female; Folic Acid; Humans; Liver Diseases; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Association of vitamins and amino acids in the therapy of chronic liver diseases. Clinical results].
Topics: Adolescent; Adult; Aged; Arginine; Citrulline; Female; Folic Acid; Humans; Liver Diseases; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Clinical considerations on the use of a new preparation with hepatoprotective action].
Topics: Adult; Aged; Arginine; Citrulline; Female; Folic Acid; Humans; Liver Diseases; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Clinico-metabolic observations on the use in therapy of a combination of vitamin B-12, folic acid, nicotinamide and amino acids of the arginine group in patients with chronic liver diseases].
Topics: Adult; Aged; Arginine; Citrulline; Folic Acid; Humans; Liver Diseases; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Clinical experimentation with a new preparation: Polilevo].
Topics: Arginine; Citrulline; Folic Acid; Humans; Liver Diseases; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
Regulation of arginase activity by intermediates of the arginine biosynthetic pathway in Neurospora crassa.
Topics: Arginase; Arginine; Autoanalysis; Carbon Dioxide; Carbon Isotopes; Cell-Free System; Chromatography, Gel; Citrulline; Colorimetry; Culture Media; Genetics, Microbial; Hydrolysis; Mutation; Neurospora; Neurospora crassa; Ornithine; Proline | 1972 |
Interactions between amino acid transport systems in Neurospora crassa.
Topics: Amino Acids; Arginine; Biological Transport, Active; Canavanine; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Citrulline; Drug Resistance, Microbial; Genetics, Microbial; Lysine; Membrane Transport Proteins; Mutation; Neurospora; Neurospora crassa; Stereoisomerism; Tryptophan | 1972 |
Argininosuccinate synthetase-lyase activity in vaccinia virus-infected HeLa and mouse L cells.
Topics: Animals; Arginine; Carbon Radioisotopes; Cell-Free System; Citrulline; Dactinomycin; Enzyme Repression; Floxuridine; HeLa Cells; Humans; L Cells; Ligases; Lyases; Mice; Puromycin; Succinates; Vaccinia virus; Viral Plaque Assay; Viral Proteins; Virus Replication | 1973 |
Control of the flux to arginine in Neurospora crassa: de-repression of the last three enzymes of the arginine pathway.
Topics: Arginine; Citrulline; Enzyme Repression; Genotype; Glycine; Histidine; Ligases; Lyases; Mutation; Neurospora; Neurospora crassa; Ornithine; Ornithine Carbamoyltransferase; Succinates | 1974 |
[Factors participating in the formation of Cl. perfringens BP6K alpha-toxin in media of determined chemical composition. I. The mechanism of the stimulating effect of an excess of arginine on toxin formation].
Topics: Arginine; Bicarbonates; Bile Acids and Salts; Caseins; Citrulline; Clostridium perfringens; Culture Media; Hydrogen-Ion Concentration; Ornithine; Quaternary Ammonium Compounds; Toxins, Biological; Tryptophan | 1969 |
[A study of the arginine desimidase system in toxigenic and weak-toxigenic strains of Clostridium perfringens type A].
Topics: Arginine; Citrulline; Clostridium perfringens; Hydrolases; Toxins, Biological; Vitamin B Complex | 1969 |
Carbamyl phosphate synthesis in a land snail, Strophocheilus oblongus.
Topics: Adenosine Triphosphate; Animals; Arginine; Aspartic Acid; Bicarbonates; Carbamates; Carbon Isotopes; Centrifugation, Density Gradient; Citrulline; Cytoplasm; Electron Transport Complex IV; Glutamates; Glutamine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Microscopy, Electron; Mitochondria; Nucleotides; Ornithine; Ornithine Carbamoyltransferase; Phosphoric Acids; Phosphotransferases; Pyrimidines; Snails; Transferases | 1970 |
A non-functional arginine biosynthetic pathway in polyoma infected-mouse embryo cells.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cells, Cultured; Citrulline; Embryo, Mammalian; Glutamates; Mice; Ornithine; Ornithine Carbamoyltransferase; Polyomavirus; Proline; Virus Replication | 1972 |
On the nature of argR mutations is Saccharomyces cerevisiae.
Topics: Amino Acyl-tRNA Synthetases; Aminocaproates; Arginine; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; Citrulline; Guanidines; Kinetics; Mutation; Ornithine; Oxidation-Reduction; Periodic Acid; RNA, Transfer; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Time Factors; Ultracentrifugation | 1974 |
Acetylglutamate kinase: a feedback-sensitive enzyme of arginine biosynthesis in Neurospora.
Topics: Arginine; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Ion Exchange; Citrulline; Enzyme Activation; Feedback; Glutamates; Hydroxylamines; Kinetics; Lysine; Magnesium; Neurospora; Neurospora crassa; Ornithine; Phosphotransferases | 1974 |
Characterization of amino acid pools in the vacuolar compartment of Saccharomyces cerevisiae.
Topics: Amino Acids; Arginine; Carbon Radioisotopes; Cell Fractionation; Centrifugation, Density Gradient; Citrulline; Cytoplasm; Glutamates; Glutamine; Inclusion Bodies; Microscopy, Phase-Contrast; Saccharomyces cerevisiae; Time Factors; Vacuoles | 1974 |
[Arginase and urease synthesis in Micrococcus denitrificans Beij. under aerobic and anaerobic culture conditions].
Topics: Ammonium Chloride; Arginase; Arginine; Citrulline; Culture Media; Micrococcus; Nitrates; Ornithine; Oxygen; Urea; Urease | 1969 |
Effect of x-irradiation on hydra in the presence of arginine and citruline and study of the radiolytic products.
Topics: Animals; Arginine; Citrulline; Cnidaria; Radiation Effects | 1970 |
Letter: On a late developing urea cycle.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Citrulline; Humans; Ligases; Lysine; Ornithine Carbamoyltransferase; Succinates; Urea | 1974 |
Letter: The high levels of lysine, homocitrulline, and homoarginine found in argininosuccinate synthetase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Citrulline; Humans; Ligases; Lysine; Succinates | 1974 |
Letter: The presence of the homoanalogues of substrates of the urea cycle in the presence of argininosuccinate synthetase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Citrulline; Diet; Humans; Ligases; Lysine; Ornithine Carbamoyltransferase; Succinates | 1974 |
Yolk sac fluid and yolk sac membrane enzymes in the marsupial, Macropus eugenii.
Topics: Animals; Arginine; Aspartic Acid; Bicarbonates; Carbamates; Carbon Radioisotopes; Cell Membrane; Chromatography, Paper; Chromatography, Thin Layer; Citric Acid Cycle; Citrulline; Egg Yolk; Electrophoresis, Polyacrylamide Gel; Embryo, Mammalian; Female; Fumarates; Glucose; Glucosephosphate Dehydrogenase; Glutamates; Glycolysis; Ketoglutaric Acids; L-Lactate Dehydrogenase; Malate Dehydrogenase; Malates; Marsupialia; Ornithine Carbamoyltransferase; Ovum; Pyruvates; Succinates | 1974 |
Argininosuccinicaciduria: clinical, metabolic and dietary study.
Topics: Affective Symptoms; Amino Acid Metabolism, Inborn Errors; Ammonia; Arginase; Arginine; Ataxia; Child; Citrulline; Dietary Proteins; Electroencephalography; Epilepsy; Female; Humans; Intellectual Disability; Intelligence Tests; Male; Ornithine; Phenobarbital; Seizures; Succinates; Tremor | 1974 |
[Amino acid levels in the blood serum of patients with chronic colitis].
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline; Colitis; Glutamates; Glutamine; Glycine; Histidine; Humans; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Urea | 1974 |
Detection of inborn errors of metabolism. III. Defects in urea cycle metabolism.
Topics: Arginine; Autoradiography; Carbon Radioisotopes; Cells, Cultured; Citrulline; Fibroblasts; Humans; Ligases; Lyases; Metabolism, Inborn Errors; Succinates | 1974 |
Arginine dihydrolase activity in species of the genus Bacillus revealed by thin-layer chromatography.
Topics: Arginine; Bacillus; Chromatography, Thin Layer; Citrulline; Hydrolases; Hydrolysis; Ornithine; Putrescine; Species Specificity | 1974 |
Continuous production of L-citrulline by immobilized Pseudomonas putida cells.
Topics: Acrylamides; Arginine; Bromides; Citrulline; Gels; Hot Temperature; Hydrogen-Ion Concentration; Hydrolases; Polymers; Pseudomonas; Quaternary Ammonium Compounds; Temperature; Time Factors | 1974 |
Metabolism of (14C)citrulline in the perfused sheep and goat udder.
Topics: Animals; Arginine; Carbon Dioxide; Citrulline; Female; Goats; Lactation; Mammary Glands, Animal; Pregnancy; Proline; Sheep | 1974 |
Adaptation of cultured human lymphoblasts to growth in citrulline.
Topics: Arginine; Burkitt Lymphoma; Cell Line; Chromosome Aberrations; Citrulline; Clone Cells; Culture Media; Female; Humans; Infectious Mononucleosis; Lesch-Nyhan Syndrome; Leukemia, Lymphoid; Ligases; Lyases; Lymphocytes; Male; Ornithine | 1974 |
The effects of arginine deficiency on lymphoma cells.
Topics: Animals; Arginase; Arginine; Carbon Radioisotopes; Cell Count; Cell Line; Cell Survival; Cells, Cultured; Citrulline; Leucine; Leukemia L1210; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Mice; Neoplasms, Experimental; Ornithine; Succinates; Thymidine; Tritium; Uridine | 1974 |
Protein arginine biosynthesis by amphibian liver tissue during metamorphosis.
Topics: Animals; Arginine; Carbon Isotopes; Citrulline; In Vitro Techniques; Liver; Metamorphosis, Biological; Protein Biosynthesis; Puromycin; Rana catesbeiana; Thyroxine; Urea | 1972 |
A concerted response of the enzymes of urea biosynthesis during thyroxine-induced metamorphosis of Rana catesbeiana.
Topics: Adenosine Triphosphate; Ammonia; Animals; Anura; Arginase; Arginine; Aspartic Acid; Carbon Dioxide; Citrulline; Larva; Ligases; Liver; Lyases; Metamorphosis, Biological; Mitochondria, Liver; Organ Size; Ornithine; Ornithine Carbamoyltransferase; Phosphotransferases; Rana catesbeiana; Subcellular Fractions; Succinates; Thyroxine; Urea | 1972 |
Regulation of argE-argH expression with arginine derivatives in Escherichia coli: extreme non-uniformity of repression and conditional repressive action.
Topics: Acetylation; Acetyltransferases; Aldehyde Oxidoreductases; Amidohydrolases; Arginine; Cell-Free System; Citrulline; Culture Media; Enzyme Repression; Escherichia coli; Glutamates; Ligases; Lyases; Ornithine; Ornithine Carbamoyltransferase; Phosphotransferases; Stereoisomerism; Succinates; Transaminases | 1973 |
Control of arginine biosynthesis in Escherichia coli: inhibition of arginyl-transfer ribonucleic acid synthetase activity.
Topics: Amino Acyl-tRNA Synthetases; Arginine; Carbon Isotopes; Cell-Free System; Chromatography; Chromatography, DEAE-Cellulose; Citrulline; Enzyme Repression; Escherichia coli; Hydroxyapatites; Ornithine; Ornithine Carbamoyltransferase; Succinates | 1973 |
The absorption of protons with specific amino acids and carbohydrates by yeast.
Topics: Amino Acids; Arginine; Canavanine; Carbohydrate Metabolism; Carbon Radioisotopes; Citrulline; Glycine; Lactose; Lysine; Maltose; Methionine; Mutation; Proline; Protons; Saccharomyces; Saccharomyces cerevisiae; Sucrose | 1973 |
Divergent orientation of transcription from the arginine gene ECBH cluster of Escherichia coli.
Topics: Arginine; Centrifugation, Density Gradient; Chromosome Mapping; Citrulline; Coliphages; DNA, Viral; Escherichia coli; Genes; Lysogeny; Mutation; Nucleic Acid Hybridization; Ornithine; Phosphorus Radioisotopes; RNA, Bacterial; Stereoisomerism; Transcription, Genetic; Transduction, Genetic; Tritium | 1974 |
Proline excretion and indirect suppression in Escherichia coli and Salmonella typhimurium.
Topics: Arginine; Bacteriological Techniques; Citrulline; Conjugation, Genetic; Enzyme Repression; Escherichia coli; Feedback; Glutamates; Mutation; Ornithine; Proline; Pyrrolidines; Salmonella typhimurium; Transduction, Genetic | 1974 |
[Experimental study of synergism and antagonism between the amino acids of the Krebs-Henseleit cycle].
Topics: Amino Acids; Ammonia; Animals; Arginine; Citric Acid Cycle; Citrulline; Drug Antagonism; Drug Interactions; Drug Synergism; Female; Male; Mice; Ornithine; Poisoning | 1972 |
Arginine and urea metabolism in the South American land snail, Strophoceilus oblongus.
Topics: Amino Acids; Animals; Arginase; Arginine; Aspartic Acid; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Citrulline; Glutamates; Kidney; Ligases; Liver; Lyases; Ornithine; Ornithine Carbamoyltransferase; Pancreas; Protein Biosynthesis; Snails; Succinates; Urea | 1972 |
Amino acid metabolism in chameleon liver.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Citrulline; Female; Glutamates; Glutamine; Glycine; Histidine; Keto Acids; Liver; Lizards; Lysine; Male; Methionine; Ornithine; Phenylalanine; Pyruvates; Serine; Threonine; Tryptophan | 1972 |
Ornithine cycle and uricolytic enzymes in four bivalve molluscs.
Topics: Allantoin; Animals; Arginase; Arginine; Aspartic Acid; Bivalvia; Citrulline; Digestive System; Glutamates; Kidney; Kinetics; Ligases; Lyases; Mollusca; Ornithine; Ornithine Carbamoyltransferase; Phosphotransferases; Quaternary Ammonium Compounds; Species Specificity; Succinates; Urate Oxidase; Urea; Ureohydrolases | 1972 |
The effect of long-term adaptation to different levels of salinity on urea synthesis and tissue amino acid concentrations in Rana cancrivora.
Topics: Adaptation, Physiological; Alanine; Amino Acids; Animals; Anura; Arginase; Arginine; Carbamates; Citrulline; Glycine; Ligases; Liver; Lyases; Muscles; Organophosphorus Compounds; Ornithine Carbamoyltransferase; Osmolar Concentration; Phosphotransferases; Ranidae; Sodium Chloride; Succinates; Urea | 1972 |
[Mechanism of intrahepatic accumulation of dicarboxylic amino acids during ammonia poisoning].
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Aspartic Acid; Citrates; Citrulline; Dicarboxylic Acids; Glutamates; Glutaminase; Glutamine; Liver; Malates; Ornithine; Pyruvates; Rats; Seizures; Urea | 1972 |
Relative importance of kidney and liver in synthesis of arginine by the rat.
Topics: Animals; Arginine; Brain; Carbon Isotopes; Citrulline; Kidney; Ligation; Liver; Lung; Male; Muscle Proteins; Muscles; Nerve Tissue Proteins; Rats | 1973 |
Effects of amino acids on the isolated chicken retina, and on its response to glutamate stimulation.
Topics: Amino Acids; Aminobutyrates; Animals; Arginine; Carbon Isotopes; Chickens; Chromatography, Paper; Citrulline; Cortical Spreading Depression; Glutamates; Glutarates; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Perfusion; Phenylalanine; Retina; Sclera; Taurine; Tryptophan; Tyrosine | 1973 |
Urea metabolism in an estivating terrestrial snail Bulimulus dealbatus.
Topics: Adaptation, Physiological; Ammonia; Animals; Arginase; Arginine; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Citrulline; Estivation; Ornithine Carbamoyltransferase; Phosphotransferases; Snails; Urea; Urease | 1973 |
[Citrulline containing epidermal proteins].
Topics: Animals; Arginine; Carbon Isotopes; Chromatography, Ion Exchange; Citrulline; Guinea Pigs; Hydrolysis; Injections, Intradermal; Mice; Ornithine; Proteins; Skin; Ultrafiltration | 1973 |
Use of external, biosynthetic, and organellar arginine by Neurospora.
Topics: Arginine; Carbon Isotopes; Chromatography; Chromatography, Paper; Citrulline; Colorimetry; Cytoplasm; Fungal Proteins; Neurospora; Stereoisomerism | 1973 |
Citrullinemia and an alternative urea cycle.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Citrulline; Humans; Infant; Lysine; Urea | 1973 |
[Metabolic products of microorganisms. 118. Delta-N-hydroxy-L-arginine, an amino acid antagonist from Nannizzia gypsea].
Topics: Anti-Bacterial Agents; Arginine; Bacteria; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Ion Exchange; Chromatography, Paper; Citrulline; Fungi; Hydroxylation; Mass Spectrometry; Ornithine; Spectrophotometry, Infrared; Stereoisomerism; Trichophyton; Tritium | 1973 |
Molecular specificity of the L-arginine reabsorption mechanism. Microperfusion studies in the proximal tubule of rat kidney.
Topics: Absorption; Aminobutyrates; Animals; Arginine; Canavanine; Citrulline; Guanidines; Homoserine; Kidney Tubules; Kidney Tubules, Proximal; Lysine; Ornithine; Perfusion; Propionates; Rats; Structure-Activity Relationship | 1973 |
Amino acid metabolism in chameleon tissues.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brain; Citrulline; Glutamates; Glutamine; Glycine; Histidine; Ketoglutaric Acids; Kidney; Liver; Lysine; Muscles; Myocardium; Ornithine; Oxaloacetates; Proline; Pyruvates; Reptiles; Serine; Tryptophan | 1973 |
Hyperlysinaemia. Harmless inborn error of metabolism?
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Body Height; Carbon Isotopes; Child; Citrulline; Cystine; Fibroblasts; Humans; Ketone Oxidoreductases; Lysine; Male; Ornithine | 1973 |
Improved thin-layer technique for detection of arginine dihydrolase among the Pseudomonas species.
Topics: Arginine; Carboxy-Lyases; Chromatography, Thin Layer; Citrulline; Guanidines; Hydrolases; Methods; Micropore Filters; Ornithine; Pseudomonas; Putrescine; Solvents; Species Specificity | 1973 |
[Metabolic products of microorganisms. 118. Delta-N-hydroxy-L-arginine, an amino acid antagonist from Nannizzia gypsea].
Topics: Anti-Bacterial Agents; Arginine; Bacteria; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Ion Exchange; Chromatography, Paper; Citrulline; Fungi; Hydroxylation; Mass Spectrometry; Ornithine; Spectrophotometry, Infrared; Stereoisomerism; Trichophyton; Tritium | 1973 |
Arginine-deficient mutants of Actinomyces griseoruber.
Topics: Actinomyces; Arginine; Azirines; Citrulline; Gene Frequency; Glutamates; Mutation; Nitrosourea Compounds; Ornithine; Proline; Radiation Genetics; Spores, Bacterial; Time Factors; Ultraviolet Rays | 1973 |
Amino acids requirements of measles virus in HeLa cells.
Topics: Amino Acids; Arginine; Citrulline; Culture Media; HeLa Cells; Humans; Measles virus; Methionine; Ornithine; Stereoisomerism; Time Factors; Viral Plaque Assay; Virus Replication | 1973 |
Enhanced utilization of citrulline in rabbitpox virus-infected mouse sarcoma 180 cells.
Topics: Animals; Arginine; Canavanine; Carbon Radioisotopes; Cell Count; Cell Line; Cells, Cultured; Citrulline; Culture Media; Dactinomycin; HeLa Cells; Humans; Kidney; Mice; Neoplasm Proteins; Phenylalanine; Poxviridae; Protein Biosynthesis; Rabbits; Sarcoma 180; Skin; Vaccinia virus; Viral Plaque Assay; Virus Replication | 1973 |
Renal metabolism of amino acids and ammonia in fed and fasted pregnant sheep.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Animals; Arginine; Aspartic Acid; Catheterization; Citrulline; Fasting; Female; Glutamates; Glutamine; Glycine; Hypoglycemia; Kidney; Pregnancy; Pregnancy, Animal; Regional Blood Flow; Renal Artery; Serine; Sheep | 1974 |
Chemical modification of lysine residues in ovine luteinizing hormone. Effect on biological activity.
Topics: Alkylation; Animals; Arginine; Ascorbic Acid; Binding Sites; Biological Assay; Borohydrides; Carbamates; Chromatography, Gel; Citrulline; Cyanogen Bromide; Female; Formaldehyde; Guanidines; Luteinizing Hormone; Lysine; Methylation; Ovary; Oxidation-Reduction; Protein Binding; Protein Conformation; Sheep; Structure-Activity Relationship | 1974 |
Ornithinemia, hyperammonemia, and homocitrullinuria. A disease associated with mental retardation and possibly caused by defective mitochondrial transport.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Citrulline; Dietary Proteins; Female; Humans; Intellectual Disability; Lysine; Mitochondria; Ornithine; Ornithine Carbamoyltransferase; Proline; Transaminases | 1974 |
Intracellular free amino acid concentration in human muscle tissue.
Topics: Adult; Alanine; Amino Acids; Arginine; Asparagine; Biopsy, Needle; Body Water; Chlorides; Citrulline; Extracellular Space; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Muscles; Ornithine; Phenylalanine; Proline; Serine; Taurine; Tyrosine; Valine | 1974 |
Citrulline levels and urea cycle enzymes in uremic rats.
Topics: Animals; Arginase; Arginine; Aspartic Acid; Caseins; Citrulline; Dietary Proteins; Female; Kidney; Ligases; Liver; Lyases; Male; Muscles; Nephrectomy; Ornithine Carbamoyltransferase; Rats; Succinates; Urea; Uremia | 1974 |
Citrullinemia: investigation and treatment over a four-year period.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Arginine; Child, Preschool; Citrulline; Dietary Proteins; Dipeptides; Female; Fibroblasts; Follow-Up Studies; Guanidines; Humans; Infant; Infant, Newborn; Orotic Acid; Peptide Synthases; Urea; Uric Acid | 1974 |
Hyperammonaemia in 20 families. Biochemical and genetical survey, including investigations in 3 new families.
Topics: Alanine; Ammonia; Arginine; Child, Preschool; Citrulline; Female; Genes, Dominant; Genetic Linkage; Glutamates; Glutamine; Glycine; Humans; Leucine; Liver; Lysine; Male; Metabolism, Inborn Errors; Ornithine; Ornithine Carbamoyltransferase; Sex Chromosomes | 1974 |
Severe neonatal citrullinaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Arginine; Citrulline; Dietary Carbohydrates; Dietary Proteins; Glucose; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Newborn, Diseases; Male; Seizures; Urea | 1974 |
The relationship between the formation of urea and argininosuccinate in a patient with argininosuccinic aciduria studied with labelled precursors.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Arginine; Carbamates; Carbon Radioisotopes; Citrulline; Cystinuria; Guanidines; Humans; Lyases; Male; Middle Aged; Nitrogen Isotopes; Quaternary Ammonium Compounds; Serum Globulins; Succinates; Urea | 1974 |
Differences in arginine requirement for growth among arginine-utilizing Mycoplasma species.
Topics: Animals; Arginine; Autoanalysis; Biological Assay; Citrulline; Culture Media; Glucose; HeLa Cells; Humans; Hydrolases; Immune Sera; Leuconostoc; Mycoplasma; Ornithine; Rabbits; Species Specificity | 1974 |
Urea production and putrescine biosynthesis by Escherichia coli.
Topics: Amines; Arginine; Carbon Isotopes; Citrulline; Escherichia coli; Glucose; Ornithine; Urea; Urease | 1967 |
Arginine synthesis in Proteus mirabilis.
Topics: Acyltransferases; Amidohydrolases; Arginine; Chromatography; Citrulline; Culture Media; Escherichia coli; Glutamates; Ligases; Lyases; Molecular Biology; Mutation; Ornithine; Oxidoreductases; Phosphotransferases; Proteus; Transaminases; Transferases | 1967 |
Arginine transport and metabolism in osmotically shocked and unshocked cells of Escherichia coli W.
Topics: Acetates; Arginine; Biological Transport; Canavanine; Carbon Isotopes; Carboxy-Lyases; Citrulline; Cold Temperature; Escherichia coli; Glutamates; Guanidines; Hydrochloric Acid; Leucine; Lysine; Ornithine; Osmolar Concentration; Proline; Tromethamine; Urea | 1969 |
Partial separation of two pools of arginine in Escherichia coli; preferential use of exogenous rather than endogenous arginine for the biosynthesis of 1,4-diaminobutane.
Topics: Amines; Arginine; Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Citrulline; Culture Media; Escherichia coli; Methods; Mutation; Species Specificity; Tritium | 1969 |
Inhibition of arginyl-transfer ribonucleic acid synthetase activity of Escherichia coli by arginine biosynthetic precursors.
Topics: Amino Acyl-tRNA Synthetases; Arginine; Carbon Isotopes; Cell-Free System; Citrulline; Colorimetry; Culture Media; Enzyme Repression; Escherichia coli; Ornithine; Spectrophotometry; Succinates | 1971 |
[Comparative metabolism of ornithine in healthy melon plants and plants with anthracnose].
Topics: Aminobutyrates; Arginine; Carbon Isotopes; Citrulline; Glutamates; Ornithine; Plant Diseases; Plant Proteins; Plants, Edible; Proline | 1967 |
Inhibition of cell multiplication in vitro by liver arginase.
Topics: Animals; Arginase; Arginine; Carcinogens; Cell Division; Chromatography, Gel; Citrulline; Colorimetry; In Vitro Techniques; L Cells; Liver; Nucleotides; p-Dimethylaminoazobenzene; Rats; Urea | 1967 |
Plasma amino acid levels in diabetic ketoacidosis.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Arginine; Butyrates; Child; Citrulline; Cystine; Diabetic Ketoacidosis; Female; Glycine; Histidine; Humans; Insulin; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1970 |
Catabolism of L-arginine by entrapped cells of Streptococcus faecalis ATCC8043.
Topics: Acrylamides; Arginine; Citrulline; Enterococcus faecalis; Gels; Hydrogen-Ion Concentration; Kinetics; Methods; Microscopy, Electron; Muramidase; Ornithine; Polymers; Putrescine | 1971 |
Inhibition of the self-assembly of capsid protein from f2 phage by urea.
Topics: Arginine; Carbon Isotopes; Circular Dichroism; Citrulline; Coliphages; Formamides; Guanidines; Imidazoles; Macromolecular Substances; Protein Denaturation; Purines; Pyridines; Pyrimidines; Semicarbazides; Spectrophotometry; Ultraviolet Rays; Urea; Viral Proteins | 1972 |
Early dietary management in an infant with argininosuccinase deficiency: preliminary report.
Topics: Ammonia; Arginine; Blood Urea Nitrogen; Child Development; Child, Preschool; Citrulline; Diet Therapy; Dietary Proteins; Female; Growth; Humans; Infant; Lyases; Metabolism, Inborn Errors; Succinates | 1972 |
Protein arginine biosynthesis by mammalian liver tissue during postnatal development.
Topics: Animals; Animals, Newborn; Arginine; Body Weight; Carbon Isotopes; Citrulline; DNA; Growth; In Vitro Techniques; Liver; Protein Biosynthesis; Puromycin; Rats; Urea | 1972 |
Citrulline metabolism in the perfused rat liver.
Topics: Adrenal Cortex Hormones; Ammonium Chloride; Animals; Arginine; Citrulline; Diet; Hydrocortisone; Kinetics; Liver; Male; Ornithine; Perfusion; Proline; Rats | 1972 |
A microassay for argininosuccinase in cultured cells.
Topics: Amino Acid Metabolism, Inborn Errors; Amniocentesis; Amniotic Fluid; Arginine; Carbon Isotopes; Cell Line; Cells, Cultured; Citrulline; Female; Fetal Diseases; Fibroblasts; Humans; Lyases; Male; Pregnancy; Skin; Succinates | 1972 |
Use of gas chromatography for determining catabolic products of arginine by bacteria.
Topics: Arginase; Arginine; Bacteria; Canavanine; Carboxy-Lyases; Chromatography, Gas; Citrulline; Hydrolases; Ornithine; Polyamines; Putrescine; Species Specificity; Stereoisomerism | 1972 |
Nitrogen metabolism of the South American lungfish Lepidosiren paradoxa.
Topics: Acetates; Ammonia; Animals; Arginine; Aspartic Acid; Bicarbonates; Carbon Isotopes; Citrulline; Climate; Fasting; Fishes; Glutamates; Guanidines; Leucine; Liver; Manganese; Ornithine; Serine; Stereoisomerism; Urea | 1972 |
In vivo synthesis and utilization of arginine in the rat.
Topics: Animals; Arginase; Arginine; Body Weight; Carbon Dioxide; Carbon Isotopes; Caseins; Citrulline; Diet; Guanidines; Kidney; Ligases; Liver; Lyases; Male; Muscles; Organ Size; Ornithine Carbamoyltransferase; Proteins; Rats; Spleen; Uridine | 1972 |
[Activity of liver argininosuccinate synthetase in chronic hepatic disease].
Topics: Ammonia; Animals; Arginine; Chronic Disease; Citrulline; Hepatitis; Hypoxanthines; Ligases; Liver Cirrhosis; Liver Diseases; Lung; Rabbits; Succinates | 1972 |
Metabolite distribution in cells.
Topics: Arginine; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamates; Citrulline; Genes; Histocytochemistry; Kinetics; Mutation; Neurospora; Ornithine; Ornithine Carbamoyltransferase; Phosphates; Phosphotransferases; Succinates; Uracil Nucleotides | 1972 |
Kinetics of nitrosamide formation from alkylureas, N-alkylurethans, and alkylguanidines: possible implications for the etiology of human gastric cancer.
Topics: Arginine; Carcinogens; Chemical Phenomena; Chemistry; Citrulline; Diet; Guanidines; Humans; Kinetics; Nitrites; Nitroso Compounds; Nitrosoguanidines; Nitrosourea Compounds; Sodium; Spectrophotometry; Stomach Neoplasms; Urea; Urethane | 1971 |
Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancy. Preliminary report.
Topics: Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Arginine; Aspartic Acid; Citrulline; Cystine; Female; Gestational Age; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
On the specificity of tryptic catalysis.
Topics: 1-Propanol; Acetates; Acylation; Arginine; Benzoates; Catalysis; Chemical Phenomena; Chemistry; Citrulline; Esters; Glycine; Kinetics; Lysine; Methanol; Models, Biological; Ornithine; Phenylalanine; Protein Binding; Sulfonic Acids; Thermodynamics; Toluene; Trypsin; Tyrosine | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
Detection of arginine dihydrolase in nonfermentative gram-negative bacteria by use of thin-layer chromatography.
Topics: Acinetobacter; Arginine; Bacteria; Chromatography, Thin Layer; Citrulline; Guanidines; Hydrolases; Methods; Ornithine; Pseudomonas; Species Specificity | 1971 |
Enzymatic production of L-citrulline by Pseudomonas putida.
Topics: Air; Arginine; Bacteria; Bromides; Chromatography, Paper; Citrulline; Culture Media; Enzyme Induction; Fermentation; Fungi; Glucose; Hydrogen-Ion Concentration; Hydrolases; Peptones; Phosphates; Pseudomonas; Quaternary Ammonium Compounds; Saccharomyces; Species Specificity; Stereoisomerism; Surface-Active Agents; Temperature | 1971 |
Hereditary disorders of amino acid metabolism associated with mental deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Child, Preschool; Citrulline; Deficiency Diseases; Hartnup Disease; Homocystinuria; Humans; Intellectual Disability; Maple Syrup Urine Disease; Phenylketonurias; Succinates | 1969 |
[Distribution of free amino acids in plasma in patients with a chronic lymphatic and acute leukemia].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Citrulline; Cystine; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Leukemia, Lymphoid; Lysine; Methionine; Ornithine; Phenylalanine; Prednisolone; Proline; Serine; Threonine; Triethylenemelamine; Tyrosine; Valine; Vincristine | 1971 |
The development of urea cycle enzyme activity in the liver of foetal and neonatal rats.
Topics: Animals; Animals, Newborn; Arginase; Arginine; Aspartic Acid; Carbamates; Citrulline; Female; Fetus; Ligases; Liver; Lyases; Ornithine Carbamoyltransferase; Phosphotransferases; Pregnancy; Rats; Succinates; Urea | 1970 |
Synthesis of arginine from citrulline and aspartate in preparations from wheat sprouts.
Topics: Arginine; Aspartic Acid; Chloromercuribenzoates; Chromatography, Gel; Citrulline; Hydrogen-Ion Concentration; Kinetics; Ligases; Lyases; Plants; Succinates; Temperature; Triticum | 1969 |
Modified methods for the determination of carbamyl aspartate.
Topics: Alanine; Antipyrine; Arginine; Aspartic Acid; Carbamates; Citrulline; Colorimetry; Darkness; Indicators and Reagents; Methods; Oximes; Spectrophotometry; Sulfuric Acids; Time Factors; Uracil; Urea | 1969 |
Argininosuccinic aciduria. Neonatal variant with rapid fatal course.
Topics: Arginase; Arginine; Blood Urea Nitrogen; Brain Chemistry; Chromatography, Paper; Citrulline; Female; Humans; Infant, Newborn; Lyases; Metabolism, Inborn Errors; Ornithine; Succinates; Urea | 1969 |
[The hepato-protective effect of a combination of amino acids of the Krebs-Henseleit cycle. Clinical and statistical considerations].
Topics: Adult; Aged; Arginine; Chronic Disease; Citrulline; Female; Humans; Liver Diseases; Male; Middle Aged; Ornithine | 1969 |
Brucella organisms isolated from dogs: comparison of characteristics of members of the genus Brucella.
Topics: Abortion, Veterinary; Alanine; Animals; Arabinose; Arginine; Asparagine; Brucella; Brucellosis; Citrulline; Culture Media; Dog Diseases; Dogs; Female; Galactose; Glutamates; Hematoma; Humans; Lysine; Ornithine; Pregnancy; Ribose; Xylose | 1969 |
[Action of uracil aza-derivatives in Saccharomyces cervisiae. IV. Identification in acid soluble extracts of compounds reacting positively with diacetylmonoxime].
Topics: Arginine; Aspartic Acid; Autoradiography; Carbamates; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Citrulline; Oximes; Pyrimidines; Saccharomyces; Triazines; Uracil; Urea | 1969 |
Metabolism of bovine semen. XX. Role of ammonia in interactions between the citric acid and urea cycles.
Topics: Amino Acids; Ammonia; Animals; Arginase; Arginine; Carbamates; Carbon Dioxide; Carbon Isotopes; Cattle; Cell Fractionation; Citric Acid Cycle; Citrulline; Male; Ornithine; Ornithine Carbamoyltransferase; Oxygen Consumption; Phosphotransferases; Proline; Pyruvates; Rabbits; Semen; Spermatozoa; Urea; Valerates | 1969 |
[The use of a detoxicant drug in the treatment of alcoholic toxicosis].
Topics: Adult; Alcoholic Intoxication; Alcoholism; Ammonia; Arginine; Citrulline; Female; Humans; Liver Function Tests; Male; Middle Aged; Nitrogen; Ornithine; Psychoses, Alcoholic; Transaminases | 1970 |
The participation of ornithine and citrulline in the regulation of arginine metabolism in Saccharomyces cerevisiae.
Topics: Amino Acids; Arginine; Carbon Isotopes; Citrulline; Culture Media; Depression, Chemical; Enzyme Repression; Glutamates; Lysine; Models, Biological; Mutation; Ornithine; Ornithine Carbamoyltransferase; Quaternary Ammonium Compounds; Saccharomyces; Species Specificity; Time Factors | 1970 |
Simultaneous determination of citrulline and urea using diacetylmonoxime.
Topics: Arginase; Arginine; Body Fluids; Butanones; Citrulline; Fluorescence; Hydrolases; Mathematics; Methods; Oximes; Spectrophotometry; Time Factors; Urea | 1970 |
Preferential hydrolysis of endogenous arginine by rat liver arginase.
Topics: Amino Acids; Animals; Arginase; Arginine; Aspartic Acid; Carbon Isotopes; Carboxypeptidases; Citrulline; Hippurates; Liver; Rats; Time Factors; Urea | 1970 |
Effects of modification of episilon-amino groups on the interaction of kappa- and alpha-S1-caseins.
Topics: Arginine; Calcium; Carbamates; Caseins; Chemical Phenomena; Chemistry; Citrulline; Formaldehyde; Lysine; Ultracentrifugation | 1970 |
L-homoarginine; an inhibitor of serum "bone and liver" alkaline phosphatase.
Topics: Alkaline Phosphatase; Arginine; Bone and Bones; Canavanine; Citrulline; Electrophoresis; Female; Guanidines; Humans; Isoenzymes; Liver; Lysine; Organ Specificity; Placenta; Pregnancy | 1970 |
Metabolism of basic amino acids in Pseudomonas putida. Intermediates in L-arginine catabolism.
Topics: Amides; Aminobutyrates; Ammonia; Arginine; Butyrates; Canavanine; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Citrulline; Computers; Drug Stability; Electrophoresis; Enzyme Induction; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Keto Acids; Kinetics; Malates; Paper; Pseudomonas; Tritium; Urea | 1971 |
Arginine racemase of Pseudomonas graveolens. I. Purification, crystallization, and properties.
Topics: Alcohols; Amides; Aminobutyrates; Arginine; Boron Compounds; Catalysis; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Citrulline; Crystallization; Drug Stability; Ethionine; Glutamates; Hot Temperature; Hydrogen-Ion Concentration; Hydroxylamines; Isomerases; Kinetics; Light; Lysine; Molecular Weight; Ornithine; Oxidation-Reduction; Penicillamine; Phenylhydrazines; Protein Binding; Pseudomonas; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Rotation; Spectrophotometry; Sulfates; Ultracentrifugation | 1971 |
Solic phase synthetic study of the active site region of staphylococcal nuclease-T'.
Topics: Amides; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Calcium; Chemical Phenomena; Chemistry; Chromatography, Paper; Citrulline; Deoxyribonucleases; Electrophoresis; Fluorescence; Glutamates; Lysine; Models, Structural; Peptides; Protein Binding; Ribonucleases; Spectrum Analysis; Staphylococcus; Trypsin | 1971 |
Catabolism of L-arginine in Neurospora crassa.
Topics: Arginase; Arginine; Carbon Isotopes; Citrulline; Membrane Transport Proteins; Neurospora; Nitrates; Ornithine; Quaternary Ammonium Compounds; Transaminases; Urease | 1967 |
Characteristics of the ureotelic arginase and its role in the advent of ureotelism during the metamorphosis of the Mexican axolotl.
Topics: Animals; Arginase; Arginine; Aspartic Acid; Biological Clocks; Centrifugation, Density Gradient; Citrulline; Liver; Metamorphosis, Biological; Ornithine; Rats; Triiodothyronine; Urea; Urodela | 1967 |
Citrullinemia.
Topics: Arginine; Citrulline; Humans; Metabolic Diseases | 1968 |
Citrullinemia.
Topics: Arginine; Citrulline; Humans; Metabolic Diseases | 1968 |
Separation of basic amino acids by paper electrophoresis.
Topics: Amino Acids; Arginine; Bicarbonates; Carbamates; Carbonates; Citrulline; Electrophoresis; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Lysine; Methods; Paper; Quinolines; Temperature | 1968 |
[Hereditary anomalies of the urea cycle].
Topics: Ammonia; Arginine; Citrulline; Humans; Ligases; Lyases; Metabolism, Inborn Errors; Ornithine Carbamoyltransferase; Phosphotransferases; Succinates; Urea | 1968 |
Utilization of exogenous and endogenous ornithine by Neurospora crassa.
Topics: Arginine; Citrulline; Mutation; Neurospora; Ornithine; Ornithine Carbamoyltransferase; Transaminases | 1968 |
The interaction of trypsin with neutral substrates and modifiers.
Topics: Amino Acids; Arginine; Benzene Derivatives; Benzoates; Binding Sites; Chemical Phenomena; Chemistry; Citrulline; Esters; Guanidines; Hydrogen-Ion Concentration; Isoflurophate; Ketones; Kinetics; Lysine; Phenols; Quaternary Ammonium Compounds; Toluene; Trypsin; Urea | 1968 |
Studies on the advent of ureotelism. Factors that render the hepatic arginase of the Mexican axolotl able to hydrolyse endogenous arginine.
Topics: Animals; Arginase; Arginine; Aspartic Acid; Citrulline; Liver; Manganese; Metamorphosis, Biological; Urodela | 1968 |
Synthesis of arginine from carbamoly aspartate and ornithine in preparations from wheat seedlings.
Topics: Acetone; Adenosine Triphosphate; Animals; Arginine; Aspartic Acid; Catalysis; Citrulline; Hydrogen-Ion Concentration; Kinetics; Liver; Magnesium; Ornithine; Rats; Triticum | 1968 |
Interactions between neutral and dibasic amino acids for uptake by the rat intestine.
Topics: Amino Acids; Animals; Arginine; Biological Transport; Carbon Isotopes; Citrulline; Intestinal Absorption; Isoleucine; Kinetics; Leucine; Methionine; Rats | 1968 |
Studies on canavanine and its derivatives.
Topics: Arginine; Canavanine; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Paper; Citrulline; Electrophoresis; Imidazoles; Oxazines; Urea | 1968 |
Biosynthesis of arginine in L cells infected with chlamydiae.
Topics: Arginine; Carbon Isotopes; Chlamydia; Citrulline; Glutamates; L Cells; Ornithine | 1968 |
The regulation and kinetics of the two ornithine transcarbamylase enzymes of Bacillus licheniformis.
Topics: Arginine; Bacillus; Carbon Isotopes; Citrulline; Culture Media; Enzyme Induction; Enzyme Repression; Glucose; Glutamates; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Ornithine; Ornithine Carbamoyltransferase | 1968 |
Metabolism of ammonia. I. Biochemical aspect of ammonia intoxication.
Topics: Ammonia; Animals; Arginine; Ascorbic Acid; Autoradiography; Bicarbonates; Blood-Brain Barrier; Carbon Isotopes; Chickens; Citrulline; Hydrogen-Ion Concentration; Injections, Intraperitoneal; Male; Mice; Ornithine; Phosphates; Poisoning; Rats; Sulfates; Time Factors | 1968 |
[The ornithine cycle in chick embryos].
Topics: Animals; Arginine; Chick Embryo; Citrulline; Liver; Ornithine; Ornithine Carbamoyltransferase; Urea | 1968 |
[Therapy of hyperammoniemia].
Topics: Adenosine Triphosphate; Ammonia; Anti-Bacterial Agents; Arginine; Aspartic Acid; Citrulline; Dietary Proteins; Hepatic Encephalopathy; Humans; Intestines; Malates; Ornithine | 1969 |
Further studies of L-arginine biosynthesis in germinating pea seeds. Evidence for the presence of argininosuccinate synthetase in cotyledon extracts.
Topics: Adenosine Triphosphate; Arginine; Aspartic Acid; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Citrulline; Hydrogen-Ion Concentration; Kinetics; Ligases; Lyases; Magnesium; Plant Extracts; Plants; Seeds; Succinates | 1969 |
[Metabolism of ammonium compounds. II. Distribution of ammonium ion (NH4), arginine, citrulline and urea in different test tissues in normal rats poisoned with ammonium ion and protected with arginine].
Topics: Animals; Arginine; Bicarbonates; Brain; Citrulline; Injections, Intraperitoneal; Kidney; Liver; Pancreas; Phosphates; Quaternary Ammonium Compounds; Rats; Sulfates; Urea | 1969 |
Effect of glucagon on concentration of several free amino acids in plasma.
Topics: Alanine; Amino Acids; Arginine; Citrulline; Cystine; Depression, Chemical; Fasting; Female; Glucagon; Glycine; Histidine; Humans; Leucine; Liver; Lysine; Male; Methionine; Nitrogen; Phenylalanine; Progesterone; Proline; Serine; Threonine; Tyrosine; Valine | 1969 |
Inhibition of urea cycle enzymes by aspartic acid analogues.
Topics: Animals; Arginase; Arginine; Aspartic Acid; Carbamates; Citrulline; In Vitro Techniques; Ligases; Liver; Lyases; Magnesium; Male; Ornithine Carbamoyltransferase; Oxaloacetates; Oxidative Phosphorylation; Phosphates; Phosphotransferases; Rats; Succinates; Urea | 1969 |
Glutamate oxidation in rat-liver homogenate.
Topics: Adenine Nucleotides; Ammonia; Animals; Arginine; Aspartic Acid; Citrulline; Glutamates; Glutaminase; Glutamine; Kinetics; Liver; Nitrogen; Rats; Urea; Urease | 1969 |
Alteration in the amino acid content of yeast during growth under various nutritional conditions.
Topics: Amino Acids; Arginine; Aspartic Acid; Biotin; Citrulline; Culture Media; Ornithine; Saccharomyces | 1969 |
Urea cycle in the silkworm, BOMBYX MORI.
Topics: Animals; Arginine; Autoradiography; Bombyx; Carbon Isotopes; Chromatography, Thin Layer; Citrulline; Deficiency Diseases; Diet; Glutamates; Ornithine; Proline; Urea | 1969 |
The homotropic cooperative effect in the case of N-acetylglutamate 5-phosphotransferase.
Topics: Arginine; Binding Sites; Canavanine; Chemical Phenomena; Chemistry; Citrulline; Eukaryota; Feedback; Glutamates; Hydrogen-Ion Concentration; Phosphotransferases; Temperature | 1969 |
[Congenital metabolic disorders of the urea cycle].
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Citrulline; Female; Humans; Infant; Infant, Newborn; Male; Succinates; Urea | 1969 |
Arginine metabolism in Chlamydomonas reinhardi. On the regulation of the arginine biosynthesis.
Topics: Arginine; Carbon Isotopes; Citrulline; Eukaryota; Lyases; Ornithine | 1969 |
[Metabolism of ammonia. 3. Effect in vitro of arginine on the physiological activity of the urea cycle enzymes during ammonia poisoning].
Topics: Ammonia; Animals; Arginase; Arginine; Citrulline; Epinephrine; Hormones; In Vitro Techniques; Ligases; Liver; Norepinephrine; Ornithine; Rats; Transferases; Urea | 1969 |
Nutritional evidence for the absence of the complete ornithine-urea cycle in the insect, Argyrotaenia velutinana (Lepidoptera: Tortricidae).
Topics: Acetates; Animal Nutritional Physiological Phenomena; Animals; Arginine; Citrulline; Creatine; Diet; Guanidines; Insecta; Metamorphosis, Biological; Ornithine; Reproduction; Urea | 1969 |
Nitrogen metabolism of Picea glauca. IV. Metabolism of uniformly labelled 14-C-L-arginine, [carbamyl-14C]-L-citrulline, and [1,2,3,4-14C]-gamma-guanidinobutyric acid during diurnal changes in the soluble and protein nitrogen associated with the onset of e
Topics: Amino Acids; Arginine; Autoradiography; Butyrates; Carbon Dioxide; Carbon Isotopes; Chromatography, Paper; Circadian Rhythm; Citrulline; Guanidines; Light; Nitrogen; Plant Development; Plant Proteins; Plants; Proline; Seasons; Soil; Solubility; Time Factors; Trees; Urease | 1969 |
Argininosuccinic aciduria: clinical, biochemical, anatomical and neuropathological observations.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Arginine; Aspartic Acid; Brain; Cerebellum; Citrulline; Female; Humans; Infant; Intellectual Disability; Liver; Lyases; Myelin Sheath; Neuroglia; Succinates | 1969 |
Phenotypic comparison of Brucella ovis to the DNA-homologous Brucella species.
Topics: Alanine; Arabinose; Arginine; Asparagine; Brucella; Citrulline; Culture Media; DNA, Bacterial; Galactose; Glutamates; Lysine; Ornithine; Phenotype; Ribose; Xylose | 1969 |
A familial study of a human enzyme defect, argininosuccinic aciduria.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Citrulline; Humans; Molecular Biology; Succinates; Urine | 1964 |
Carbamyl phosphate synthesis in Neurospora crassa. II. Genetics, metabolic position, and regulation of arginine-specific carbamyl phosphokinase.
Topics: Arginine; Carbamates; Citrulline; In Vitro Techniques; Molecular Biology; Mutation; Neurospora; Ornithine Carbamoyltransferase; Phosphates; Phosphotransferases; Succinates; Transferases | 1965 |
The relationship between arginine, citrulline and ornithine in Tetrahymena pyriformis.
Topics: Arginine; Citrulline; In Vitro Techniques; Ornithine; Tetrahymena; Ureohydrolases | 1965 |
[Urea cycle in some cattle parasites (helminths)].
Topics: Animals; Arginine; Carbon Dioxide; Carbon Isotopes; Cattle; Citrulline; Fasciola hepatica; Ligases; Nitrogen; Phosphates; Taenia; Trematoda; Urea | 1965 |
Arginine and urea biosynthesis in the land planarian: its significance in biochemical evolution.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoradiography; Carbon Dioxide; Chromatography, Paper; Citrulline; Glutamates; Glutamine; Glycine; Serine; Succinates; Turbellaria; Urea | 1965 |
The absorption of dibasic amino-acids by rat intestinal slices.
Topics: Animals; Arginine; Biological Transport, Active; Buffers; Carbon Isotopes; Citrulline; Ethylmaleimide; Glucose; Intestinal Absorption; Intestinal Mucosa; Leucine; Lysine; Male; Methionine; Nitrophenols; Phlorhizin; Rats; Sodium | 1965 |
Separation of basic amino acids. IV. Electrophoretic determination of L-arginine, L-citrulline, L-histidine, L-lysine, and L-ornithine.
Topics: Arginine; Citrulline; Electrophoresis; Histidine; Lysine; Ornithine | 1965 |
Arginine metabolism in Halobacterium salinarium, an obligately halophilic bacterium.
Topics: Adenine Nucleotides; Amino Acids; Arginine; Bacterial Proteins; Citrulline; Halobacterium; In Vitro Techniques; Ornithine Carbamoyltransferase; Sodium Chloride; Temperature; Ureohydrolases | 1966 |
Linked transduction in Proteus mirabilis.
Topics: Arginine; Citrulline; Homocysteine; Methionine; Mutation; Proteus; Radiation Effects; Ultraviolet Rays; Uracil | 1966 |
Citrulline utilization in Crithidia.
Topics: Arginine; Chromatography, Ion Exchange; Citrulline; Eukaryota; Succinates | 1966 |
Beta-alanine inhibition in Neurospora and its reversal by carbamyl compounds.
Topics: Alanine; Aminobutyrates; Arginine; Asparagine; Carbamates; Citrulline; Molecular Biology; Mutation; Neurospora; Nucleosides; Uracil | 1966 |
[Studies on the metabolism of urea in microorganisms. V. The specific activity of the ornithine cycle enzymes in Endomycopsis vernalis and Torulopsis utilis in relation to the N source].
Topics: Arginase; Arginine; Ascomycota; Asparagine; Candida; Citrulline; Ligases; Ornithine; Ornithine Carbamoyltransferase; Phosphotransferases; Quaternary Ammonium Compounds; Urea | 1966 |
Studies in arginine metabolism by schistosomes. I. Arginine uptake and lysis by Schistosoma mansoni.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Citrulline; Female; Histidine; Humans; Methionine; Mice; Ovum; Schistosoma; Tryptophan | 1966 |
Argininosuccinic aciduria. Report of two new cases and demonstration of intermittent elevation of blood ammonia.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Arginine; Chromatography, Paper; Citrulline; Electroencephalography; Electrophoresis; Female; Humans; Intellectual Disability; Male; Microchemistry; Succinates | 1967 |
A case of hyperlysinemia: biochemical and clinical observations.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Autoanalysis; Child, Preschool; Chromatography, Paper; Citrulline; Humans; Intellectual Disability; Lysine; Male; Ornithine | 1967 |
A kinetic analysis of the papain-catalyzed hydrolysis of alpha-N-benzoyl-L-citrulline methyl ester.
Topics: Arginine; Chemical Phenomena; Chemistry; Citrulline; Hydrogen-Ion Concentration; Kinetics; Papain | 1967 |
On the interaction of trypsin with neutral substrates and inhibitors.
Topics: Arginine; Citrulline; Esters; Guanidines; Phenols; Protein Binding; Trypsin; Urea | 1967 |
Mechanism of arginine biosynthesis in Chlamydomonas reinhardti. II. Purification and properties of N-acetylglutamate 5-phosphotransferase, the allosteric enzyme of the pathway.
Topics: Adenosine Triphosphate; Arginine; Canavanine; Catalysis; Citrulline; Eukaryota; Glutamates; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Phosphotransferases; Urea | 1967 |
The catabolism of L-arginine by Neurospora crassa.
Topics: Arginase; Arginine; Autoanalysis; Carbon Isotopes; Citrulline; Mutation; Neurospora; Quaternary Ammonium Compounds; Transaminases; Urease | 1967 |
Citrullinemia with defective urea production.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Citrulline; Diet Therapy; Female; Humans; Infant; Infant, Newborn; Intellectual Disability; Ligases; Liver; Seizures; Urea | 1967 |
The accumulation of argininosuccinate in Neurospora crassa. I. Elevated ornithine carbamoyl transferase with high concentrations of arginine.
Topics: Arginine; Chromatography, Paper; Citrulline; Mutation; Neurospora; Ornithine Carbamoyltransferase | 1967 |
Free amino-acids in human sweat from different parts of the body.
Topics: Adolescent; Adult; Amino Acids; Arginine; Back; Child; Child, Preschool; Citrulline; Female; Hand; Humans; Infant; Male; Middle Aged; Ornithine; Sweat; Threonine; Urea | 1967 |
The effect of progesterone on the concentration of plasma amino acids in man.
Topics: Acromegaly; Alanine; Amino Acids; Arginine; Citrulline; Cystine; Fasting; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Progesterone; Proline; Proteins; Threonine; Tyrosine; Valine | 1967 |
Paths of lysine degradation in patients with hyperlysinemia.
Topics: Arginine; Carbon Isotopes; Child; Child, Preschool; Chromatography, Paper; Citrulline; Female; Humans; Lysine | 1967 |
The biosynthesis of proline by Tetrahymena pyriformis.
Topics: Acids; Alanine; Arginine; Carbon Isotopes; Citrulline; Glutamates; Hot Temperature; Hydrogen-Ion Concentration; Hydrolases; Ketoglutaric Acids; Kinetics; Metals; Ornithine; Oxidoreductases; Proline; Protein Denaturation; Pyrroles; Tetrahymena; Transaminases; Ureohydrolases; Valine | 1967 |
Argininosuccinate synthetase of Neurospora crassa.
Topics: Adenosine Triphosphate; Aminobutyrates; Arginine; Aspartic Acid; Chemical Precipitation; Citrulline; Hydrogen-Ion Concentration; Kinetics; Ligases; Neurospora | 1967 |
Biochemical characterization of arginine muants in Schizosaccharomyces pombe and the possibility of repression.
Topics: Arginine; Ascomycota; Citrulline; Culture Media; Enzyme Repression; Mutation; Neurospora; Nitrites; Ornithine; Proline; Radiation Genetics; Succinates | 1967 |
Arginine metabolism in infected cell cultures as a marker character for the differentiation of orthopoxviruses.
Topics: Animals; Arginine; Cells, Cultured; Chick Embryo; Citrulline; Culture Media; DNA, Viral; Ectromelia virus; Fibroblasts; HeLa Cells; Mice; Poxviridae; Sarcoma 180; Vaccinia virus | 1984 |
Toxic effects of ornithine and its related compounds on the retina.
Topics: Animals; Arginine; Citrulline; Glutamates; Glutamic Acid; Lysine; Ornithine; Pigment Epithelium of Eye; Proline; Putrescine; Rats; Rats, Inbred Strains; Retina | 1982 |
Arginine uptake by isolated rat liver mitochondria.
Topics: Animals; Arginine; Citrulline; Glutamates; Glutamic Acid; Glutamine; Lysine; Male; Mitochondria, Heart; Mitochondria, Liver; Ornithine; Rats; Rats, Inbred Strains | 1984 |
Control of the ornithine cycle in Neurospora crassa by the mitochondrial membrane.
Topics: Arginine; Citrulline; Cytosol; Intracellular Membranes; Kinetics; Mitochondria; Mutation; Neurospora; Neurospora crassa; Ornithine | 1983 |
Transport of basic aminoacids in E. coli.
Topics: Amino Acids; Arginine; Biological Transport, Active; Citrulline; Diamines; Escherichia coli; Glucose; Hydrogen-Ion Concentration; Ornithine; Structure-Activity Relationship | 1984 |
Oral administration of urea cycle intermediates in lysinuric protein intolerance: effect on plasma and urinary arginine and ornithine.
Topics: Administration, Oral; Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Arginine; Child; Citrulline; Female; Humans; Intestinal Absorption; Lysine; Ornithine; Urea | 1983 |
"Basolateral" and mitochondrial membrane transport defect in the hepatocytes in lysinuric protein intolerance.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Arginine; Cell Membrane; Child; Citrulline; Female; Humans; Liver; Lysine; Male; Mitochondria, Liver; Ornithine | 1983 |
[Release in secondary mixed leukocyte cultures of a factor inducing citrulline production by bone marrow cells].
Topics: Animals; Arginine; Bone Marrow; Cells, Cultured; Citrulline; Female; Leukocytes; Lymphokines; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Solubility | 1983 |
The uptake of ornithine and lysine by rat liver mitochondria.
Topics: Animals; Arginine; Biological Transport; Citrulline; Female; In Vitro Techniques; Lysine; Mitochondria, Liver; Ornithine; Rats; Rats, Inbred Strains | 1983 |
[Lysinuric protein intolerance].
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Citrulline; Consanguinity; Dietary Proteins; Female; Ferritins; Humans; Infant; L-Lactate Dehydrogenase; Lysine; Ornithine; Turkey | 1983 |
Bacillus subtilis 168 mutants resistant to arginine hydroxamate in the presence of ornithine or citrulline.
Topics: Arginine; Bacillus subtilis; Chromosome Mapping; Citrulline; Drug Resistance, Microbial; Mutation; Ornithine; Transduction, Genetic | 1984 |
Complementation between arginiosuccinate synthetase-deficient and argininosuccinate lyase-deficient fibroblasts depends on intercellular communication.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Argininosuccinic Acid; Cell Communication; Cell Line; Citrulline; Fibroblasts; Humans; Infant, Newborn | 1984 |
Control of the flux in the arginine pathway of Neurospora crassa. The flux from citrulline to arginine.
Topics: Arginine; Citrulline; Kinetics; Models, Biological; Neurospora; Neurospora crassa; Urea | 1980 |
Restoration of aerial mycelium and antibiotic production in a Streptomyces griseoflavus arginine auxotroph.
Topics: Amino Acids; Anti-Bacterial Agents; Arginine; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Citrulline; Drug Resistance, Microbial; Ethionine; Methionine Adenosyltransferase; Mutation; Ornithine; S-Adenosylmethionine; Spores, Bacterial; Streptomyces | 1984 |
Mechanism of arginine protection against ammonia intoxication in the rat.
Topics: Acetyltransferases; Amino-Acid N-Acetyltransferase; Ammonia; Animals; Arginine; Carbamoyl-Phosphate Synthase (Ammonia); Citrulline; Male; Mitochondria, Liver; Ornithine; Ornithine Carbamoyltransferase; Orotic Acid; Rats; Rats, Inbred Strains; Urea | 1984 |
Treatment of congenital hyperammonemias.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Citrulline; Humans; Metabolism, Inborn Errors; Nitrogen; Serotonin; Urea | 1984 |
Biosynthesis of the spermidine moiety of glycocinnamoylspermidine antibiotic cinodine.
Topics: Aminoglycosides; Anti-Bacterial Agents; Arginine; Citrulline; Nocardia; Spermidine; Urea | 1984 |
Citrulline in proteins from the enzymatic deimination of arginine residues.
Topics: Amino Acids; Animals; Arginine; Citrulline; Colorimetry; Humans; Hydrolases; Indicators and Reagents; Kinetics; Molecular Weight; Organ Specificity; Proteins; Species Specificity | 1984 |
Hyperammonemia.
Topics: Acetyltransferases; Amino Acid Metabolism, Inborn Errors; Amino-Acid N-Acetyltransferase; Ammonia; Arginine; Argininosuccinate Synthase; Argininosuccinic Aciduria; Brain Edema; Carbamoyl-Phosphate Synthase (Ammonia); Child, Preschool; Citrulline; Diagnosis, Differential; Female; Humans; Hyperargininemia; Infant; Infant, Newborn; Leucine; Ornithine Carbamoyltransferase; Respiratory Distress Syndrome, Newborn; Urea | 1984 |
Biosynthesis of the spermidine and guanidino units in the glycocinnamoylspermidine antibiotic cinodine.
Topics: Aminoglycosides; Anti-Bacterial Agents; Arginine; Citrulline; Guanidines; Ornithine; Spermidine | 1984 |
Regulation of enzymes involved in ornithine/arginine metabolism in the parasitic trypanosomatid Herpetomonas samuelpessoai.
Topics: Amidohydrolases; Arginine; Argininosuccinate Lyase; Biological Transport, Active; Canavanine; Citrulline; Eukaryota; Gene Expression Regulation; Kinetics; Lyases; Ornithine; Ornithine Carbamoyltransferase | 1983 |
Regulation of biosynthesis of guanidinosuccinic acid in isolated rat hepatocytes and in vivo.
Topics: Amino Acids; Ammonium Chloride; Animals; Arginine; Citrulline; Guanidines; In Vitro Techniques; Liver; Male; Ornithine; Rats; Rats, Inbred Strains; Succinates; Urea; Valine | 1983 |
[A patient with neonatal citrullinemia].
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Benzoates; Benzoic Acid; Citrulline; Exchange Transfusion, Whole Blood; Humans; Infant, Newborn; Male | 1983 |
A sensitive assay for the enzyme activity in hair follicles and epidermis that catalyses the peptidyl-arginine-citrulline post-translational modification.
Topics: Animals; Arginine; Autoradiography; Biotransformation; Calcium; Citrulline; Dipeptides; Electrophoresis, Paper; Enzyme Activation; Epidermis; Guinea Pigs; Hair; In Vitro Techniques; Kinetics; Protein Processing, Post-Translational; Substrate Specificity | 1983 |
Metabolic cooperation between argininosuccinate synthetase and argininosuccinate lyase deficient human fibroblasts.
Topics: Arginine; Argininosuccinate Synthase; Argininosuccinic Acid; Argininosuccinic Aciduria; Cell Communication; Cell Count; Cell Line; Citrulline; Culture Media; Fibroblasts; Humans; Intercellular Junctions; Kinetics; Leucine; Lymphocytes; Mutation; Protein Biosynthesis | 1984 |
Urea cycle function in the dog with emphasis on the role of arginine.
Topics: Age Factors; Ammonia; Animals; Arginine; Blood Glucose; Citrulline; Dogs; Ornithine; Orotic Acid; Urea; Vomiting | 1984 |
Oral administration of arginine and citrulline in the treatment of lysinuric protein intolerance.
Topics: Administration, Oral; Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids, Diamino; Arginine; Child; Citrulline; Humans; Male | 1984 |
Enzyme inhibition as a possible cause of secondary increases in metabolite levels in patients with inborn errors of metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonium Chloride; Ammonium Sulfate; Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Argininosuccinic Acid; Cattle; Citrulline; Ligases; Liver; Lyases; Lysine; Rats; Swine | 1980 |
Lysinuric protein intolerance: a two-year trial of dietary supplementation therapy with citrulline and lysine.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Arginine; Child; Child, Preschool; Citrulline; Complement C3; Female; Growth; Hemoglobins; Humans; Infant; Infant, Newborn; Lysine; Male; Serum Albumin | 1980 |
Argininosuccinic acid synthetase deficiency in a hamster cell line and its complementation of argininosuccinic aciduria human fibroblasts.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Argininosuccinic Acid; Cell Line; Citrulline; Cricetinae; Female; Fibroblasts; Genes, Recessive; Genetic Complementation Test; HeLa Cells; Humans; Hybrid Cells; Ligases; Liver; Lyases; Male; Renal Aminoacidurias | 1980 |
A new transport interaction of dibasic amino acids and citrulline in human kidney.
Topics: Amino Acids; Arginine; Biological Transport; Citrulline; Humans; Kidney; Lysine; Male; Ornithine | 1981 |
A conditional aerial mycelium-negative mutant of Streptomyces fradiae with deficient ornithine carbamoyltransferase activity.
Topics: Arginine; Citrulline; Mutation; Ornithine Carbamoyltransferase; Streptomyces | 1983 |
pryB mutations as suppressors of arginine auxotrophy in Salmonella typhimurium.
Topics: Arginine; Aspartate Carbamoyltransferase; Carbamyl Phosphate; Citrulline; Genes; Mutation; Ornithine; Salmonella typhimurium; Suppression, Genetic | 1980 |
Formation of arginine and guanidinoacetic acid in the kidney in vivo. Their relations with the liver and their regulation.
Topics: Animals; Arginine; Citrulline; Diabetes Mellitus, Experimental; Diet; Glycine; Hepatectomy; Insulin; Kidney; Male; Nephrectomy; Ornithine; Rats | 1981 |
Treatment of inborn errors of urea synthesis: activation of alternative pathways of waste nitrogen synthesis and excretion.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Essential; Ammonia; Arginine; Argininosuccinate Synthase; Argininosuccinic Aciduria; Benzoates; Benzoic Acid; Carbamoyl-Phosphate Synthase (Ammonia); Child, Preschool; Citrulline; Coma; Female; Humans; Infant; Infant, Newborn; Infusions, Parenteral; Male; Nitrogen; Ornithine Carbamoyltransferase Deficiency Disease; Urea | 1982 |
Successful treatment of severe OTC deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Benzoates; Benzoic Acid; Citrulline; Humans; Infant, Newborn; Male; Ornithine Carbamoyltransferase Deficiency Disease | 1982 |
A neonatal screening test for argininosuccinic acid lyase deficiency and other urea cycle disorders.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Argininosuccinic Aciduria; Blood Specimen Collection; Citric Acid Cycle; Citrulline; Humans; Infant, Newborn; Lyases; Mass Screening; Ornithine; Urea | 1982 |
Complementation in argininosuccinate synthetase and argininosuccinate lyase deficiencies in human fibroblasts.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Argininosuccinate Synthase; Argininosuccinic Acid; Argininosuccinic Aciduria; Cells, Cultured; Citrulline; Fibroblasts; Genetic Complementation Test; Humans; Ligases; Lyases | 1982 |
Dynamism of rat liver ornithine metabolisms in relation to dietary high-protein stimulation of the urea cycle.
Topics: Animals; Arginine; Biological Transport, Active; Citrulline; Cytosol; Dietary Proteins; Liver; Mitochondria, Liver; Ornithine; Proline; Rats; Urea | 1982 |
Regulation of urea synthesis: changes in the concentration of ornithine in the liver corresponding to changes in urea synthesis.
Topics: Ammonium Chloride; Animals; Arginine; Citrulline; Dietary Proteins; Glutamates; Liver; Male; Ornithine; Rats; Rats, Inbred Strains; Stimulation, Chemical; Urea | 1982 |
Transient hyperammonemias in infants with and without organic acidemia.
Topics: Acetyltransferases; Amino Acid Metabolism, Inborn Errors; Amino-Acid N-Acetyltransferase; Ammonia; Arginine; Carbamoyl-Phosphate Synthase (Ammonia); Citrulline; Humans; Infant, Newborn; Infant, Newborn, Diseases; Liver; Time Factors; Urea | 1982 |
Ammonia metabolism in dogs with portacaval shunts.
Topics: Ammonia; Animals; Arginine; Body Weight; Citrulline; Dogs; Female; Liver; Nitrogen; Organ Size; Orotic Acid; Portacaval Shunt, Surgical; Urea | 1982 |
Studies on complementation in argininosuccinate synthetase and argininosuccinate lyase deficiencies in human fibroblasts.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Argininosuccinate Synthase; Argininosuccinic Acid; Argininosuccinic Aciduria; Cell Line; Citrulline; Female; Fibroblasts; Genetic Complementation Test; Humans; Infant, Newborn; Infant, Newborn, Diseases; Ligases; Lyases; Male; Polyethylene Glycols | 1981 |
[Variations in the plasma concentration of ornithine, citrulline and arginine in acute experimental liver failure].
Topics: Acute Disease; Amino Acids; Animals; Arginine; Citrulline; Female; Liver Diseases; Ornithine; Swine | 1981 |
Arginine, mitochondrial arginase, and the control of carbamyl phosphate synthesis.
Topics: Animals; Arginase; Arginine; Carbamates; Carbamyl Phosphate; Citrulline; In Vitro Techniques; Kinetics; Male; Mitochondria, Liver; Ornithine; Rats; Submitochondrial Particles; Urea | 1981 |
Effects of arginine-free meals on ureagenesis in cats.
Topics: Acetyltransferases; Amino-Acid N-Acetyltransferase; Ammonia; Animals; Arginine; Cats; Citrulline; Food, Formulated; Kinetics; Liver; Mitochondria, Liver; Ornithine; Ornithine-Oxo-Acid Transaminase; Transaminases | 1981 |
Arginine as competitive inhibitor of argininosuccinate synthetase from guinea pig liver.
Topics: Animals; Arginine; Argininosuccinate Synthase; Aspartate Ammonia-Lyase; Citrulline; Guinea Pigs; Kinetics; Ligases; Liver; Male | 1981 |
Mouse macrophage arginase.
Topics: Animals; Arginase; Arginine; Biological Assay; Cell Division; Cells, Cultured; Citrulline; Hydrogen-Ion Concentration; Kinetics; Macrophages; Manganese; Mice; Mice, Inbred DBA; Substrate Specificity | 1980 |
Arginine synthesis and nitrogen excretion in the myxomycete Physarum polycephalum.
Topics: Ammonia; Arginine; Citrulline; Nitrogen; Physarum; Urea; Urease; Uric Acid | 1980 |
Partial purification and specificity of an arginine-converting enzyme from bovine epidermis.
Topics: Animals; Arginine; Cattle; Citrulline; Epidermis; Substrate Specificity | 1980 |
Separation and estimation of arginine-related metabolites in tissues.
Topics: Animals; Arginine; Chromatography, Ion Exchange; Citrulline; Glutamates; Glutamine; Humans; Male; Ornithine; Polyamines; Proline; Rats; Urea | 1980 |
Diagnostic value of orotic acid excretion in heritable disorders of the urea cycle and in hyperammonemia due to organic acidurias.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Child; Child, Preschool; Citrulline; Female; Humans; Infant; Infant, Newborn; Male; Metabolism, Inborn Errors; Middle Aged; Orotic Acid | 1980 |
Therapy of urea cycle enzymopathies: three case studies.
Topics: Ammonia; Arginine; Argininosuccinic Acid; Argininosuccinic Aciduria; Child, Preschool; Citrulline; Coma; Female; Humans; Infant; Infant, Newborn; Intellectual Disability; Lyases; Male; Ornithine Carbamoyltransferase Deficiency Disease; Urea | 1981 |
Nitric oxide as a retrograde messenger in the nucleus tractus solitarii of rats during hypoxia.
Topics: Animals; Arginine; Citrulline; Dizocilpine Maleate; Drug Combinations; Enzyme Inhibitors; Glutamic Acid; Hypercapnia; Hypoxia; Male; Microinjections; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Respiration; Solitary Nucleus | 1995 |
L-arginine deficiency and hemodynamic changes as a result of arginase efflux following orthotopic liver transplantation.
Topics: Adult; Arginase; Arginine; Blood Pressure; Citrulline; Diastole; Female; Humans; Liver Transplantation; Male; Monitoring, Intraoperative; Nitrates; Nitrites; Ornithine; Pulmonary Wedge Pressure; Reperfusion | 1995 |
Reduction of nitric oxide synthase activity in human neutrophils by oxidized low-density lipoproteins. Reversal of the effect of oxidized low-density lipoproteins by high-density lipoproteins and L-arginine.
Topics: Arginine; Cholesterol; Citrulline; Enzyme Inhibitors; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Neutrophils; Nitric Oxide Synthase; Nitroarginine; Oxidation-Reduction; Time Factors | 1995 |
Increased production of nitric oxide by neutrophils and monocytes from cirrhotic patients with ascites and hyperdynamic circulation.
Topics: Adult; Aged; Arginine; Ascites; Blood Platelets; Citrulline; Enzyme Inhibitors; Female; Guanosine Monophosphate; Heart Rate; Humans; Lipopolysaccharides; Liver Cirrhosis; Male; Middle Aged; Monocytes; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Platelet Aggregation; Platelet Aggregation Inhibitors; Stroke Volume; Tritium | 1995 |
Hypoxia inhibits L-arginine synthesis from L-citrulline in porcine pulmonary artery endothelial cells.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Citrulline; Culture Techniques; Endothelium, Vascular; Glutamine; Hypoxia; Pulmonary Artery; Swine | 1995 |
Oligomerization of endothelial nitric oxide synthase. Evidence for a dominant negative effect of truncation mutants.
Topics: Animals; Arginine; Cell Line; Chlorocebus aethiops; Citrulline; Endothelium, Vascular; Epitopes; Isoenzymes; Kinetics; Macromolecular Substances; Mutagenesis; Myristic Acid; Myristic Acids; Nitric Oxide Synthase; Protein Processing, Post-Translational; Recombinant Proteins; Restriction Mapping; Sequence Deletion; Sequence Tagged Sites; Transfection | 1995 |
Characterization by electron paramagnetic resonance of the interactions of L-arginine and L-thiocitrulline with the heme cofactor region of nitric oxide synthase.
Topics: Animals; Arginine; Binding Sites; Cell Line; Citrulline; Electron Spin Resonance Spectroscopy; Heme; Kidney; Nitric Oxide Synthase; Protein Conformation; Rats; Recombinant Proteins; Thermodynamics; Thiourea; Transfection | 1995 |
Response of cerebral blood vessels to an endogenous inhibitor of nitric oxide synthase.
Topics: Animals; Arginine; Basilar Artery; Brain; Cerebellum; Cerebrovascular Circulation; Citrulline; Nitric Oxide Synthase; Rabbits; Rats; Rats, Sprague-Dawley | 1995 |
Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Citrulline; Cyclic GMP; Dexamethasone; Disease Models, Animal; Homoarginine; Hypertension; Insulin; Male; Nitrates; Nitric Oxide; Ornithine; Rats; Rats, Inbred Strains | 1993 |
The role of P-type calcium channels in the depolarization-induced activation of nitric oxide synthase in frontal cortex.
Topics: Amiloride; Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Calcium Channel Blockers; Calcium Channels; Carrier Proteins; Citrulline; Enzyme Activation; Frontal Lobe; In Vitro Techniques; Male; N-Methylaspartate; Nitric Oxide Synthase; Nitroarginine; omega-Conotoxins; Peptides; Pipecolic Acids; Polyamines; Potassium; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger | 1994 |
Inhibition by methylene blue of the L-arginine metabolism to L-citrulline coupled with nitric oxide synthesis in cultured endothelial cells.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Citrulline; Endothelium, Vascular; Ionomycin; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Superoxide Dismutase | 1993 |
An L-arginine-nitric oxide-cyclic guanosine monophosphate system exists in the uterus and inhibits contractility during pregnancy.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Culture Techniques; Cyclic GMP; Dose-Response Relationship, Drug; Female; Labor, Obstetric; Methylene Blue; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Pregnancy; Progesterone; Rats; Rats, Sprague-Dawley; Uterine Contraction; Uterus | 1994 |
Eclosion hormone-mediated signal transduction in the silkworm abdominal ganglia: involvement of a cascade from inositol(1,4,5)trisphosphate to cyclic GMP.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bombyx; Calcium; Citrulline; Cyclic GMP; Egtazic Acid; Enzyme Activation; Ganglia, Invertebrate; Inositol 1,4,5-Trisphosphate; Insect Hormones; Neomycin; Nitric Oxide Synthase; Nitroarginine; p-Methoxy-N-methylphenethylamine; Second Messenger Systems; Signal Transduction; Sulfonamides | 1994 |
Inducible nitric oxide synthase is increased in murine lung epithelial cells by cytokine stimulation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Citrulline; Cytokines; Dexamethasone; Enzyme Induction; Epithelium; Guanidines; Interferon-gamma; Interleukin-1; Kinetics; Lung; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Recombinant Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha | 1994 |
Effect of ageing on tissue levels of amino acids involved in the nitric oxide pathway in rat brain.
Topics: Aging; Amino Acid Oxidoreductases; Amino Acids; Animals; Arginine; Aspartic Acid; Brain Chemistry; Citrulline; Glutamates; Glutamic Acid; Male; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Wistar | 1993 |
Argininosuccinate synthetase mRNA and activity are induced by immunostimulants in vascular smooth muscle. Role in the regeneration or arginine for nitric oxide synthesis.
Topics: Adjuvants, Immunologic; Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Argininosuccinate Synthase; Base Sequence; Cells, Cultured; Citrulline; Cycloheximide; Cytosol; Dactinomycin; Dexamethasone; DNA Primers; Enzyme Induction; Interferon-gamma; Kinetics; Lipopolysaccharides; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Recombinant Proteins; RNA, Messenger | 1994 |
The citrulline biosynthetic operon, argC-F, and a ribose transport operon, rbs, from Bacillus subtilis are negatively regulated by Spo0A.
Topics: Arginine; Bacillus subtilis; Bacterial Proteins; Base Sequence; beta-Galactosidase; Chromosomes, Bacterial; Citrulline; Culture Media; DNA, Bacterial; Gene Expression Regulation, Bacterial; Genes, Bacterial; Molecular Sequence Data; Operon; Protein Engineering; Recombinant Fusion Proteins; Ribose; RNA, Bacterial; Spores, Bacterial; Transcription Factors; Transcription, Genetic | 1994 |
Selective targeting of nitric oxide synthase inhibitors to system y+ in activated macrophages.
Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems; Animals; Arginine; Biological Transport, Active; Canavanine; Carrier Proteins; Cell Line; Citrulline; Lipopolysaccharides; Macrophage Activation; Macrophages; Membrane Glycoproteins; Membrane Proteins; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Receptors, Virus | 1994 |
Inhibition of calcium-dependent nitric oxide synthase causes ileitis and leukocytosis in guinea pigs.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Cyclic GMP; Female; Guanidines; Guinea Pigs; Ileitis; Leukocyte Count; Leukocytosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peroxidase | 1994 |
Inhibition of nitric oxide synthase by antineoplastic anthracyclines.
Topics: Aclarubicin; Amino Acid Oxidoreductases; Animals; Arginine; Brain Chemistry; Citrulline; Doxorubicin; Male; Nitric Oxide Synthase; Rats; Rats, Wistar | 1994 |
L-citrulline reverses the inhibition of nonadrenergic, noncholinergic relaxations produced by nitric oxide synthase inhibitors in guinea pig trachea and human bronchus.
Topics: Adult; Amino Acid Oxidoreductases; Animals; Arginine; Bronchi; Citrulline; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Male; Muscle Relaxation; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Trachea | 1994 |
Nitric-oxide synthase assays.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Chromatography, Ion Exchange; Citrulline; Dithiothreitol; Hemoglobins; Indicators and Reagents; Mammals; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; Pterins; Sensitivity and Specificity; Spectrophotometry | 1994 |
Modification of striatal arginine and citrulline metabolism by nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Corpus Striatum; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1994 |
On the mechanism of the nitric oxide synthase-catalyzed conversion of N omega-hydroxyl-L-arginine to citrulline and nitric oxide.
Topics: Amino Acid Oxidoreductases; Arginine; Catalysis; Citrulline; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Temperature | 1994 |
Expression of nitric oxide synthase in rat glomerular mesangial cells mediated by cyclic AMP.
Topics: Adenylyl Cyclases; Amino Acid Oxidoreductases; Animals; Antimetabolites; Arginine; Blotting, Northern; Cells, Cultured; Citrulline; Cyclic AMP; Cytosol; Enzyme Activation; Glomerular Mesangium; Interleukin-1; Kinetics; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; RNA, Messenger; Tumor Necrosis Factor-alpha; Up-Regulation | 1994 |
Metabolism of methylarginines by human vasculature; implications for the regulation of nitric oxide synthesis.
Topics: Amino Acid Oxidoreductases; Arginase; Arginine; Cells, Cultured; Chromatography, High Pressure Liquid; Citrulline; Cytosol; Endothelium, Vascular; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Saphenous Vein; Umbilical Veins | 1994 |
Dexamethasone inhibits the expression of an inducible nitric oxide synthase in infarcted rabbit myocardium.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Coronary Vessels; Cyclic GMP; Dexamethasone; Ligation; Male; Myocardial Infarction; Myocardium; Nitric Oxide Synthase; Rabbits | 1994 |
Constitutive expression of inducible nitric oxide synthase in human bronchial epithelial cells induces c-fos and stimulates the cGMP pathway.
Topics: Amino Acid Oxidoreductases; Animals; Antigens, Polyomavirus Transforming; Arginine; Base Sequence; Blotting, Northern; Bronchi; Carbon Radioisotopes; Cell Division; Cell Line, Transformed; Citrulline; Cyclic GMP; DNA Primers; Enzyme Induction; Epithelium; Gene Expression; Genes, fos; Humans; Kinetics; Mice; Molecular Sequence Data; Nitric Oxide Synthase; Polymerase Chain Reaction; Proto-Oncogene Proteins c-fos; Simian virus 40; Transfection | 1994 |
Effect of hydrogen peroxide and catalase on rat cerebellum nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Catalase; Cerebellum; Citrulline; Hydrogen Peroxide; In Vitro Techniques; Nitric Oxide; Nitric Oxide Synthase; Rats; Tetrazolium Salts | 1994 |
Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group. Role of tetrahydrobiopterin in modulating the inhibitory action of nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Carbon Monoxide; Cerebellum; Citrulline; Cyanides; Heme; NADP; Neurons; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Oxyhemoglobins; Rats; Sulfhydryl Compounds; Superoxide Dismutase | 1994 |
Prolonged inhibition of brain nitric oxide synthase by short-term systemic administration of nitro-L-arginine methyl ester.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Citrulline; Cytosol; Dose-Response Relationship, Drug; Injections, Intravenous; Kinetics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prosencephalon; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Calcium-dependent inhibition of constitutive nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Calcineurin; Calcium Chloride; Calmodulin; Calmodulin-Binding Proteins; Citrulline; Kinetics; Nitric Oxide Synthase; Phosphoprotein Phosphatases; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; Trifluoperazine; Tritium | 1994 |
A bacterial nitric oxide synthase from a Nocardia species.
Topics: Amino Acid Oxidoreductases; Arginine; Biopterins; Calcium; Citrulline; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nocardia; Oxygen | 1994 |
L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthases.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding Sites; Citrulline; Cytochrome c Group; Heme; Kinetics; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Thiourea | 1994 |
Potent and selective inhibition of human nitric oxide synthases. Selective inhibition of neuronal nitric oxide synthase by S-methyl-L-thiocitrulline and S-ethyl-L-thiocitrulline.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Binding Sites; Binding, Competitive; Cerebral Cortex; Citrulline; Cytosol; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Induction; Humans; In Vitro Techniques; Isoenzymes; Kinetics; Nitric Oxide Synthase; Rats; Thiourea; Time Factors | 1994 |
Human colon cancer cell lines show a diverse pattern of nitric oxide synthase gene expression and nitric oxide generation.
Topics: Adenocarcinoma; Amino Acid Oxidoreductases; Arginine; Base Sequence; Citrulline; Colonic Neoplasms; Gene Expression; Humans; Isoenzymes; Lipopolysaccharides; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; RNA, Messenger; Tumor Cells, Cultured | 1994 |
Presence of constitutive type nitric oxide synthase in cultured astrocytes isolated from rat cerebra.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Astrocytes; Brain; Cells, Cultured; Citrulline; Cyclic GMP; Histocytochemistry; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats | 1994 |
Polyamines inhibit nitric oxide synthase in rat cerebellum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cerebellum; Citrulline; Cytosol; Eflornithine; Kinetics; N-Methylaspartate; Neurons; Nitric Oxide Synthase; omega-N-Methylarginine; Polyamines; Putrescine; Rats; Spermidine; Spermine; Tritium | 1994 |
Localization of nitric oxide synthase activity in the human lower urinary tract and its correlation with neuroeffector responses.
Topics: Amino Acid Oxidoreductases; Arginine; Citrulline; Electric Stimulation; Guanylate Cyclase; Humans; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NADPH Dehydrogenase; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Urethra; Urinary Bladder | 1994 |
In vitro endotoxin exposure induces contractile dysfunction in adult rat cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cell Survival; Cells, Cultured; Citrulline; Cyclic GMP; Dactinomycin; Electric Stimulation; Endotoxins; Heart; Kinetics; Male; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitroprusside; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Physiological concentrations of melatonin inhibit nitric oxide synthase in rat cerebellum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cerebellum; Citrulline; Dose-Response Relationship, Drug; Egtazic Acid; Female; In Vitro Techniques; Male; Melatonin; Nitric Oxide Synthase; Rats | 1994 |
Characterization of the inactivation of nitric oxide synthase by NG-methyl-L-arginine: evidence for heme loss.
Topics: Amino Acid Oxidoreductases; Arginine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Citrulline; Cytochrome P-450 Enzyme System; Enzyme Stability; Heme; Hemeproteins; Hydrogen Peroxide; Isotope Labeling; Nitric Oxide Synthase; omega-N-Methylarginine; Solubility; Spectrophotometry; Tritium | 1994 |
Electron transfer in the nitric-oxide synthases. Characterization of L-arginine analogs that block heme iron reduction.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Transport; Cells, Cultured; Citrulline; Cloning, Molecular; Electrons; Heme; Humans; Iron; Kinetics; NADP; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Rats; Thiourea | 1994 |
Dexamethasone up-regulates a constitutive nitric oxide synthase in cerebellar astrocytes but not in granule cells in culture.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Astrocytes; Calcimycin; Cells, Cultured; Citrulline; Cycloheximide; Dexamethasone; Dose-Response Relationship, Drug; Lipopolysaccharides; Neurons; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Up-Regulation | 1995 |
Regulation of nitric oxide synthase activity in cortical slices by excitatory amino acids and calcium.
Topics: Amino Acid Oxidoreductases; Amino Acids; Animals; Arginine; Calcium; Cerebral Cortex; Citrulline; Cycloleucine; In Vitro Techniques; Male; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1994 |
CGRP enhances induction of NO synthase in vascular smooth muscle cells via a cAMP-dependent mechanism.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Calcitonin Gene-Related Peptide; Cells, Cultured; Citrulline; Colforsin; Cyclic AMP; Interleukin-1; Isoproterenol; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Platelet Aggregation; Protein Kinases; Rats; Rats, Wistar; RNA, Messenger; Thionucleotides | 1994 |
Characteristics of the nitric oxide synthase-catalyzed conversion of arginine to N-hydroxyarginine, the first oxygenation step in the enzymic synthesis of nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Catalysis; Cell Line; Chromatography, High Pressure Liquid; Citrulline; Humans; Kidney; Kinetics; Nitric Oxide Synthase; Oxidation-Reduction; Rats; Recombinant Proteins; Transfection; Tritium | 1995 |
A novel in vivo assay system for consecutive measurement of brain nitric oxide production combined with the microdialysis technique.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Citrulline; Extracellular Space; Male; Microdialysis; Neostriatum; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1994 |
Reduction by NG-nitro-L-arginine of H2O2-induced endothelial cell injury.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cattle; Cell Survival; Cells, Cultured; Chromium Radioisotopes; Citrulline; Endothelium, Vascular; Hydrogen Peroxide; L-Lactate Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine | 1994 |
Effect of lipopolysaccharide on nitric oxide synthase activity in rat proximal tubules.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Kidney Tubules, Proximal; Kinetics; Lipopolysaccharides; Male; NADP; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1995 |
Inhibition of neuronal nitric oxide synthase by antipsychotic drugs.
Topics: Amino Acid Oxidoreductases; Animals; Antipsychotic Agents; Arginine; Brain Neoplasms; Calmodulin; Cerebellum; Citrulline; Cyclic GMP; Cytosol; In Vitro Techniques; Male; Mice; Neuroblastoma; Neurons; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 1994 |
Hydrogen peroxide-supported oxidation of NG-hydroxy-L-arginine by nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Benzene Derivatives; Cell Line; Citrulline; Hydrogen Peroxide; Kinetics; Macrophages; Mice; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; Oxygen; Peroxides; tert-Butylhydroperoxide | 1995 |
Molecular mechanisms of inhibition of porcine brain nitric oxide synthase by the antinociceptive drug 7-nitro-indazole.
Topics: Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Binding, Competitive; Biopterins; Brain; Citrulline; Enzyme Inhibitors; Hydrogen Peroxide; Indazoles; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Protein Binding; Swine | 1994 |
Identification of constitutive and inducible forms of nitric oxide synthase in human platelets.
Topics: Amino Acid Oxidoreductases; Arginine; Blood Platelets; Citrulline; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Humans; Nitric Oxide Synthase; Nitrites; Nitroarginine; Platelet Aggregation; Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 1995 |
Effect of opioid receptor agonists on nitric oxide synthase activity in rat cerebral cortex homogenate.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebral Cortex; Citrulline; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 1994 |
Amplification of nitric oxide synthase expression by nitric oxide in interleukin 1 beta-stimulated rat mesangial cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Northern; Cell Nucleus; Citrulline; Gene Expression Regulation, Enzymologic; Glomerular Mesangium; Interleukin-1; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Penicillamine; Rats; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Transcription, Genetic | 1995 |
Induction of calcium-independent nitric oxide synthase activity in cultured cerebellar granule neurons.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cytokines; Interferon-gamma; Lipopolysaccharides; Neurons; Nitric Oxide Synthase; Rats; Rats, Wistar; Salmonella typhimurium | 1995 |
Protein kinase C is a mediator of lipopolysaccharide-induced vascular suppression in the rat aorta.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Cell Membrane; Citrulline; Cycloheximide; Cytosol; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Isoquinolines; Kinetics; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phorbol 12,13-Dibutyrate; Piperazines; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Stereoisomerism; Sulfonamides | 1994 |
Increase in serum NG-hydroxy-L-arginine in rats treated with bacterial lipopolysaccharide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Escherichia coli; Lipopolysaccharides; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Stereoisomerism | 1995 |
Impairment of nitrergic-mediated relaxation of rat isolated duodenum by experimental diabetes.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Diabetes Mellitus, Experimental; Dimethylphenylpiperazinium Iodide; Duodenum; In Vitro Techniques; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Rats; Rats, Wistar; Tissue Preservation | 1995 |
Nitric oxide synthase activity in molluscan hemocytes.
Topics: Amino Acid Oxidoreductases; Animals; Antibodies; Arginine; Citrulline; Hemocytes; Kinetics; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rabbits; Snails | 1995 |
Ca(2+)-independent nitric oxide synthase activity in human lung after cardiopulmonary bypass.
Topics: Amino Acid Oxidoreductases; Arginine; Calcium; Cardiopulmonary Bypass; Citrulline; Heart Diseases; Humans; Lung; Nitric Oxide Synthase; Postoperative Period | 1995 |
Ca(2+)-dependent and Ca(2+)-independent NO-synthesizing activities of human primordial placenta.
Topics: Amino Acid Oxidoreductases; Arginine; Calcium; Citrulline; Cytosol; Egtazic Acid; Female; Guanidines; Humans; Microsomes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Placenta; Pregnancy; Pregnancy Trimester, First; Time Factors; Tritium | 1994 |
Direct and reversible inhibition of endothelial nitric oxide synthase by nitric oxide.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Aorta; Arginine; Cattle; Cells, Cultured; Citrulline; Dithiothreitol; Endothelium, Vascular; Kinetics; Luminescent Measurements; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oxyhemoglobins; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Tritium; Vasodilator Agents | 1995 |
Endotoxin-induced contractile dysfunction in guinea pig hearts is not mediated by nitric oxide.
Topics: Adenine Nucleotides; Amino Acid Oxidoreductases; Animals; Arginine; Cerebellum; Chromatography, High Pressure Liquid; Citrulline; Coronary Circulation; Endotoxins; Energy Metabolism; Enzyme Induction; Guinea Pigs; Heart; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphocreatine; Vascular Resistance; Ventricular Function, Left | 1995 |
The nitric oxide transduction pathway in Trypanosoma cruzi.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Cyclic GMP; Dizocilpine Maleate; Guanylate Cyclase; Nitric Oxide; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate; Trypanosoma cruzi | 1995 |
Cytochrome P450IIIA activity and cytokine-mediated synthesis of nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Cimetidine; Citrulline; Cytochrome P-450 Enzyme System; Cytokines; Isomerism; Male; Molecular Probes; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; Polymerase Chain Reaction; Rats; Rats, Inbred Lew; RNA, Messenger; Transcription, Genetic | 1995 |
Erythrocyte stages of Plasmodium falciparum exhibit a high nitric oxide synthase (NOS) activity and release an NOS-inducing soluble factor.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Factors; Canavanine; Cell Adhesion; Cells, Cultured; Citrulline; Culture Media, Conditioned; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; Erythrocytes; Host-Parasite Interactions; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Plasmodium; Plasmodium falciparum; Protozoan Proteins; Species Specificity; Umbilical Veins | 1995 |
Adenosine modulates N-methyl-D-aspartate-stimulated hippocampal nitric oxide production in vivo.
Topics: 2-Chloroadenosine; Adenosine; Amino Acid Oxidoreductases; Animals; Arginine; Carbon Radioisotopes; Citrulline; Excitatory Amino Acid Antagonists; Hippocampus; Male; N-Methylaspartate; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norbornanes; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines | 1995 |
Purification and characterization of nitric oxide synthase (NOSNoc) from a Nocardia species.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Arginine; Chromatography, Liquid; Citrulline; Enzyme Stability; Hydrogen-Ion Concentration; Molecular Sequence Data; Molecular Weight; NADP; Nitric Oxide Synthase; Nocardia; Oxidation-Reduction; Oxygen Consumption; Sequence Analysis; Substrate Specificity | 1995 |
Nitric oxide synthase activity is inducible in rat, but not rabbit alveolar macrophages, with a concomitant reduction in arginase activity.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Citrulline; Cytokines; Dexamethasone; Enzyme Induction; Female; In Vitro Techniques; Lipopolysaccharides; Macrophages, Alveolar; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Rabbits; Rats; Rats, Sprague-Dawley | 1995 |
Reconstitution of the second step in NO synthesis using the isolated oxygenase and reductase domains of macrophage NO synthase.
Topics: Arginine; Citrulline; Electron Transport; Kinetics; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Oxidoreductases; Oxygenases; Substrate Specificity | 1995 |
Nitric oxide modulates pepsinogen secretion induced by calcium-mediated agonist in guinea pig gastric chief cells.
Topics: Animals; Arginine; Calcium; Calmodulin; Carbachol; Cells, Cultured; Cholecystokinin; Citrulline; Cyclic GMP; Egtazic Acid; Gastric Mucosa; Gastrins; Guinea Pigs; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pepsinogens; Terpenes; Thapsigargin | 1995 |
Induction of nitric oxide synthase in colonic smooth muscle from patients with toxic megacolon.
Topics: Adult; Aged; Arginine; Citrulline; Colitis, Ulcerative; Colon; Colonic Neoplasms; Endotoxins; Enzyme Induction; Female; Humans; Immunohistochemistry; In Vitro Techniques; Male; Megacolon, Toxic; Middle Aged; Muscle, Smooth; Nitric Oxide Synthase | 1995 |
Neuronal nitric oxide synthase self-inactivates by forming a ferrous-nitrosyl complex during aerobic catalysis.
Topics: Aerobiosis; Animals; Arginine; Brain; Catalysis; Cell Line; Citrulline; Computer Simulation; Ferrous Compounds; Humans; Kidney; Kinetics; Models, Theoretical; NADP; Neurons; Nitric Oxide; Nitric Oxide Synthase; Oxyhemoglobins; Rats; Recombinant Proteins; Spectrophotometry; Spectrum Analysis, Raman; Superoxides; Transfection | 1995 |
Treatment of ammonia intoxication in rats through the use of amino acids from the urea cycle.
Topics: Acetates; Analysis of Variance; Animals; Arginine; Citrulline; Injections, Intraperitoneal; Ketoglutaric Acids; Male; Ornithine; Poisoning; Rats; Rats, Wistar; Survival Rate; Urea | 1995 |
Relations among arginine, citrulline, ornithine, and leucine kinetics in adult burn patients.
Topics: Adult; Aged; Arginine; Blood Proteins; Burns; Carbon Isotopes; Citrulline; Female; Humans; Isotope Labeling; Kinetics; Leucine; Male; Middle Aged; Nitrogen Isotopes; Ornithine; Parenteral Nutrition, Total | 1995 |
Induction of NG-monomethyl-L-arginine uptake: a mechanism for differential inhibition of NO synthases?
Topics: Animals; Arginine; Biological Transport; Cell Line; Citrulline; Cytokines; Endothelium, Vascular; Endotoxins; Humans; Kinetics; Macrophages; Mice; Nitric Oxide Synthase; omega-N-Methylarginine; Time Factors | 1995 |
Arginine synthesis in enterocytes of neonatal pigs.
Topics: Aging; Animals; Animals, Newborn; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Body Fluids; Citrulline; DNA; Glutamine; Jejunum; Kidney; Ornithine; Osmolar Concentration; Proline; Swine | 1995 |
Thiol dependence of nitric oxide synthase.
Topics: Animals; Arginine; Biopterins; Cerebellum; Citrulline; Kinetics; NADP; Nitric Oxide Synthase; Rats; Structure-Activity Relationship; Sulfhydryl Compounds; Swine | 1995 |
Characterization of the effects of two new arginine/citrulline analogues on constitutive and inducible nitric oxide synthases in rat aorta.
Topics: Acetylcholine; Adenosine Diphosphate; Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Calcimycin; Citrulline; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Ionophores; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar; Thiourea; Vasoconstrictor Agents | 1995 |
Sites of arginine synthesis and urea production along the nephron of a desert rodent species, Meriones shawi.
Topics: Animals; Arginine; Citrulline; Gerbillinae; Kidney; Male; Nephrons; Urea | 1995 |
Expression of the citrulline-nitric oxide cycle in rodent and human pancreatic beta-cells: induction of argininosuccinate synthetase by cytokines.
Topics: Animals; Arginine; Argininosuccinate Synthase; Cells, Cultured; Citrulline; Cytokines; Enzyme Induction; Humans; Insulinoma; Islets of Langerhans; Nitric Oxide; Pancreatic Neoplasms; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Cells, Cultured | 1995 |
In vivo production of nitric oxide correlates with NMDA-induced cerebral hyperemia in newborn sheep.
Topics: 2-Chloroadenosine; Animals; Animals, Newborn; Arginine; Blood Volume; Cerebrovascular Circulation; Citrulline; Drug Combinations; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Parietal Lobe; Sheep | 1995 |
Nitric oxide synthase in the autonomic nervous system of canine ileum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Autonomic Nervous System; Calcium; Citrulline; Cyclic GMP; Dogs; Guanylate Cyclase; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Subcellular Fractions; Synaptosomes; Tritium | 1993 |
Prevention of diabetic vascular dysfunction by guanidines. Inhibition of nitric oxide synthase versus advanced glycation end-product formation.
Topics: Aldehyde Reductase; Amino Acid Oxidoreductases; Animals; Arginine; Benzothiazoles; Blood Pressure; Body Weight; Capillary Permeability; Citrulline; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Glycation End Products, Advanced; Guanidines; Imidazoles; Imidazolidines; Inositol; Iodine Radioisotopes; Male; Methylguanidine; Naphthalenes; Nitric Oxide Synthase; omega-N-Methylarginine; Phthalazines; Rats; Rats, Sprague-Dawley; Retina; Sciatic Nerve; Serum Albumin, Bovine; Sorbitol; Thiazoles; Uvea | 1993 |
Cytotoxicity of activated rat macrophages against syngeneic islet cells is arginine-dependent, correlates with citrulline and nitrite concentrations and is identical to lysis by the nitric oxide donor nitroprusside.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Female; Islets of Langerhans; Kinetics; Macrophage Activation; Macrophages; Male; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Thionucleotides | 1993 |
Bovine bronchial epithelial cells metabolize L-arginine to L-citrulline: possible role of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bronchi; Cattle; Cells, Cultured; Citrulline; Epithelial Cells; Epithelium; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; Smoke | 1993 |
Feedback inhibition of nitric oxide synthase activity by nitric oxide.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Citrulline; Enzyme Induction; Feedback; Glutathione; Hemoglobins; Interferon-gamma; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroso Compounds; Penicillamine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione | 1993 |
Selective inhibition of the inducible nitric oxide synthase by aminoguanidine.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Guanidines; Macrophages; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence | 1993 |
Irreversible inactivation of macrophage and brain nitric oxide synthase by L-NG-methylarginine requires NADPH-dependent hydroxylation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Cell Line; Chromatography, High Pressure Liquid; Citrulline; Humans; Hydroxylation; Kinetics; Macrophages; Mice; NADP; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Recombinant Proteins | 1993 |
Particular ability of liver P450s3A to catalyze the oxidation of N omega-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Arginine; Catalysis; Citrulline; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; Isoenzymes; Male; Microsomes, Liver; Molecular Sequence Data; Nitric Oxide Synthase; Nitrogen Oxides; Oxidation-Reduction; Rats | 1993 |
Stimulation of bovine brain phospholipase C activity by myelin basic protein requires arginyl residues in peptide linkage.
Topics: Animals; Arginine; Brain; Cattle; Citrulline; Hydrolases; Myelin Basic Protein; Peptides; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Polylysine; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Sequence Analysis; Structure-Activity Relationship; Trypsin | 1993 |
Nitric oxide-generating system as an autocrine mechanism in human polymorphonuclear leucocytes.
Topics: 1-Methyl-3-isobutylxanthine; Arginine; Biological Transport; Citrulline; Cyclic GMP; Endothelins; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroprusside; omega-N-Methylarginine | 1993 |
NG-methyl-L-arginine functions as an alternate substrate and mechanism-based inhibitor of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Catalase; Citrulline; Formaldehyde; Hydrogen Peroxide; In Vitro Techniques; Macrophages; Mice; NADP; Nitric Oxide Synthase; omega-N-Methylarginine; Structure-Activity Relationship; Superoxide Dismutase | 1993 |
Glutamine metabolism in chick enterocytes: absence of pyrroline-5-carboxylase synthase and citrulline synthesis.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Animals; Arginine; Cells, Cultured; Chickens; Citrulline; Glutamine; Intestinal Mucosa; Male; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Proline; Swine | 1995 |
Studies of calcineurin-calmodulin interaction: probing the role of arginine residues using peptidylarginine deiminase.
Topics: Animals; Arginine; Blotting, Western; Brain; Calcineurin; Calmodulin; Calmodulin-Binding Proteins; Cattle; Citrulline; Electrophoresis, Polyacrylamide Gel; Hydrolases; Kinetics; Phosphoprotein Phosphatases; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Time Factors | 1995 |
Arginine synthesis from citrulline in perivascular nerves of cerebral artery.
Topics: Animals; Arginase; Arginine; Cerebral Arteries; Citrulline; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Male; NADPH Dehydrogenase; Nervous System; Nitroarginine; Swine; Urease | 1995 |
Nitric oxide mediates chemoreceptor inhibition in the cat carotid body.
Topics: Animals; Arginine; Carotid Body; Cats; Chemoreceptor Cells; Citrulline; Cyclic GMP; Electric Stimulation; Evoked Potentials; Hypoxia; Immunohistochemistry; Nitric Oxide | 1995 |
Enhancement of macrophage microbicidal activity: supplemental arginine and citrulline augment nitric oxide production in murine peritoneal macrophages and promote intracellular killing of Trypanosoma cruzi.
Topics: Animals; Arginine; Chagas Disease; Citrulline; Female; Immunity, Cellular; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; Trypanosoma cruzi | 1995 |
Dietary arginine deficiency and gut ammonium infusion alter flux of urea cycle intermediates across the portal-drained viscera of pigs.
Topics: Alanine; Animals; Arginine; Citrulline; Diet; Digestive System; Glutamic Acid; Glutamine; Lysine; Ornithine; Portal Vein; Quaternary Ammonium Compounds; Regional Blood Flow; Swine; Urea; Viscera | 1995 |
Plasma arginine, citrulline, and ornithine kinetics in adults, with observations on nitric oxide synthesis.
Topics: Adult; Arginine; Citrulline; Diet; Fasting; Homeostasis; Humans; Kinetics; Male; Nitric Oxide; Nitrogen Isotopes; Ornithine | 1995 |
Glutamine and glucose metabolism in enterocytes of the neonatal pig.
Topics: Adenosine Triphosphate; Aging; Animals; Animals, Newborn; Arginine; Citrulline; Glucose; Glutamine; Jejunum; Oxygen Consumption; Swine | 1995 |
Immunocytochemical evidence for a glial localisation of arginine, and a neuronal localisation of citrulline in the rat neurohypophysis: implications for nitrergic transmission.
Topics: Animals; Arginine; Aspartic Acid; Citrulline; Female; Immunohistochemistry; Male; Neuroglia; Neurons; Nitric Oxide; Pituitary Gland, Posterior; Rats; Rats, Wistar; Synaptic Transmission; Tissue Distribution | 1994 |
Brain amino acid levels are related to seizure propensity in the gerbil (Meriones unguiculatus).
Topics: Amino Acids; Analysis of Variance; Animals; Arginine; Aspartic Acid; Behavior, Animal; Brain; Citrulline; Cysteine; Disease Susceptibility; Female; Gerbillinae; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycine; Male; Seizures | 1993 |
Dietary citrulline but not ornithine counteracts dietary arginine deficiency in rats by increasing splanchnic release of citrulline.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Blood Flow Velocity; Body Weight; Citrulline; Creatinine; Diet; Food; Glutamic Acid; Glutamine; Male; Ornithine; Orotic Acid; Proline; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Urea | 1994 |
Stimulation by hydrogen peroxide of L-arginine metabolism to L-citrulline coupled with nitric oxide synthesis in cultured endothelial cells.
Topics: Animals; Aorta, Thoracic; Arginine; Calcium; Catalase; Cattle; Cells, Cultured; Citrulline; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydrogen Peroxide; L-Lactate Dehydrogenase; Nitric Oxide; Superoxide Dismutase | 1994 |
Lysinuric protein intolerance. Urinary amino acid excretion at 2 and 9 days of age.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Arginine; Citrulline; Humans; Infant, Newborn; Lysine; Male; Ornithine | 1994 |
Normalization of hair growth in sparse fur-abnormal skin and hair (SPF-ASH) mice by introduction of the rat ornithine transcarbamylase (OTC) gene.
Topics: Animals; Arginine; Citrulline; Crosses, Genetic; Disease Models, Animal; Female; Genetic Linkage; Hair; Intestine, Small; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Phenotype; Rats; Skin Abnormalities; X Chromosome | 1994 |
Cytokines induce nitric oxide production in mouse osteoblasts.
Topics: 3T3 Cells; Animals; Arginine; Cell Line; Cell Survival; Citrulline; Cycloheximide; Cytokines; Dactinomycin; Dexamethasone; Egtazic Acid; Escherichia coli; Humans; Indomethacin; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Osteoblasts; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1994 |
Hyperammonemia in Marasmic children.
Topics: Alanine Transaminase; Ammonia; Arginine; Aspartate Aminotransferases; Citrulline; Humans; Infant; Ornithine; Protein-Energy Malnutrition; Urea | 1994 |
The plasma flux and oxidation rate of ornithine adaptively decline with restricted arginine intake.
Topics: Adult; Arginine; Carbon Dioxide; Carbon Isotopes; Citrulline; Diet; Humans; Isotope Labeling; Kinetics; Male; Nitrogen Isotopes; Ornithine; Oxidation-Reduction; Time Factors | 1994 |
Nitric oxide increases renal blood flow by interacting with the sympathetic nervous system.
Topics: Animals; Arginine; Citrulline; Female; Kidney; Nitric Oxide; omega-N-Methylarginine; Rabbits; Renal Circulation; Sympathetic Nervous System | 1994 |
Plasma endothelin levels and vascular effects of intravenous L-arginine infusion in subjects with uncomplicated insulin-dependent diabetes mellitus.
Topics: Adult; Arginine; Atrial Natriuretic Factor; Blood Pressure; Citrulline; Cyclic GMP; Diabetes Mellitus, Type 1; Endothelins; Extracellular Space; Humans; Infusions, Intravenous; Male; Nitric Oxide; Sodium Chloride | 1994 |
Discrimination between citrulline and arginine transport in activated murine macrophages: inefficient synthesis of NO from recycling of citrulline to arginine.
Topics: Animals; Arginine; Biological Transport, Active; Cell Line; Citrulline; Hydrogen-Ion Concentration; Interferon-gamma; Kinetics; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Sodium | 1994 |
NMDA evokes an L-NAME sensitive spinal release of glutamate and citrulline.
Topics: Animals; Arginine; Citrulline; Dialysis; Dizocilpine Maleate; Glutamates; Glutamic Acid; Injections, Spinal; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Spinal Cord | 1993 |
Vasoactive intestinal peptide release and L-citrulline production from isolated ganglia of the myenteric plexus: evidence for regulation of vasoactive intestinal peptide release by nitric oxide.
Topics: Alkaloids; Aminoquinolines; Animals; Arginine; Carbazoles; Citrulline; Dimethylphenylpiperazinium Iodide; Ganglia, Autonomic; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Ileum; In Vitro Techniques; Indoles; Kinetics; Muscle, Smooth; Myenteric Plexus; Nitric Oxide; Nitroarginine; Protein Kinase Inhibitors; SRS-A; Tetrodotoxin; Tritium; Vasoactive Intestinal Peptide | 1993 |
In situ behavior of the pyrimidine pathway enzymes in Saccharomyces cerevisiae. 4. The channeling of carbamylphosphate to aspartate transcarbamylase and its partition in the pyrimidine and arginine pathways.
Topics: Arginine; Aspartate Carbamoyltransferase; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Cell Membrane Permeability; Citrulline; Hydrogen-Ion Concentration; Kinetics; Ligases; Ornithine Carbamoyltransferase; Pyrimidines; Saccharomyces cerevisiae; Valine | 1994 |
Purification and properties of porcine liver ornithine transcarbamylase.
Topics: Amino Acid Sequence; Animals; Arginine; Binding, Competitive; Chromatography, Affinity; Citrulline; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Hydrogen-Ion Concentration; Kinetics; Liver; Molecular Sequence Data; Molecular Weight; Ornithine; Ornithine Carbamoyltransferase; Phenylglyoxal; Phosphates; Sequence Analysis; Swine; Ultracentrifugation | 1994 |
Renal synthesis of arginine in chronic renal failure: in vivo and in vitro studies in rats with 5/6 nephrectomy.
Topics: Amino Acids; Animals; Arginine; Citrulline; Hemodynamics; Hypertrophy; In Vitro Techniques; Kidney Failure, Chronic; Kidney Tubules, Proximal; Male; Nephrectomy; Rats; Rats, Sprague-Dawley; Reference Values; Renal Circulation | 1993 |
Cytochrome P450 dependent N-hydroxylation of a guanidine (debrisoquine), microsomal catalysed reduction and further oxidation of the N-hydroxy-guanidine metabolite to the urea derivative. Similarity with the oxidation of arginine to citrulline and nitric
Topics: Animals; Arginine; Catalysis; Citrulline; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Male; Microsomes, Liver; Nitric Oxide; Oxidation-Reduction; Rabbits; Rats; Rats, Wistar; Species Specificity; Swine; Urea | 1993 |
Chemical modification by polyethylene glycol of the anti-tumor enzyme arginine deiminase from Mycoplasma arginini.
Topics: Animals; Arginase; Arginine; Asparaginase; Citrulline; Growth Inhibitors; Hydrolases; In Vitro Techniques; Male; Mice; Mycoplasma; Polyethylene Glycols; Tumor Cells, Cultured | 1993 |
Arabidopsis chloroplasts dissimilate L-arginine and L-citrulline for use as N source.
Topics: Adenosine Triphosphate; Arabidopsis; Arginine; Bicarbonates; Cell Compartmentation; Chloroplasts; Citrulline; Hydrolases; Models, Biological; Nitrates; Nitrogen; Ornithine; Ornithine Carbamoyltransferase; Phosphotransferases (Carboxyl Group Acceptor); Quaternary Ammonium Compounds | 1993 |
Regulation of L-arginine synthesis from L-citrulline by L-glutamine in endothelial cells.
Topics: Animals; Arginine; Argininosuccinic Acid; Biological Transport; Cattle; Cells, Cultured; Citrulline; Endothelium, Vascular; Glutamine; Humans | 1993 |
Plasma arginine kinetics in adult man: response to an arginine-free diet.
Topics: Adult; Arginine; Carbon Isotopes; Chromatography, High Pressure Liquid; Citrulline; Deuterium; Fasting; Food, Formulated; Humans; Infusions, Intravenous; Keto Acids; Leucine; Male; Nitrogen Isotopes; Ornithine; Time Factors; Urea | 1994 |
Organ clearance of tyrosyl-arginine and its effect on amino acid metabolism in young sheep.
Topics: Aging; Amino Acids; Analgesics; Animals; Arginine; Citrulline; Endorphins; Female; Hindlimb; Intestinal Mucosa; Intestines; Isoleucine; Kidney; Leucine; Liver; Metabolic Clearance Rate; Organ Specificity; Phenylalanine; Regional Blood Flow; Sheep; Tyrosine; Valine | 1993 |
Plasma arginine and citrulline kinetics in adults given adequate and arginine-free diets.
Topics: Adult; Arginine; Carbon Isotopes; Citrulline; Deuterium; Diet; Humans; Isotope Labeling; Kinetics; Leucine; Male; Models, Biological; Urea | 1993 |
The activation of the arginine-citrulline cycle in macrophages from the spontaneously diabetic BB rat.
Topics: Animals; Arginine; Citrulline; Diabetes Mellitus, Type 1; Macrophages; Male; Nitrates; Peritoneal Cavity; Rats; Rats, Inbred BB | 1993 |
Intestinal arginine metabolism during development. Evidence for de novo synthesis of L-arginine in newborn pig enterocytes.
Topics: Animals; Animals, Newborn; Animals, Suckling; Arginine; Carbamyl Phosphate; Cell Separation; Chromatography, High Pressure Liquid; Citrulline; Female; Glutamine; Intestinal Mucosa; Intestines; Ornithine; Ornithine Carbamoyltransferase; Pregnancy; Swine | 1993 |
Localization of nitric oxide-related substances in the peripheral nervous tissues.
Topics: Animals; Arginine; Citrulline; Cyclic GMP; Ganglia, Spinal; Histocytochemistry; Immunohistochemistry; Intestines; Male; NADPH Dehydrogenase; Nitric Oxide; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1993 |
Prospective management of a child with neonatal citrullinemia.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Argininosuccinate Synthase; Benzoates; Benzoic Acid; Child Development; Child, Preschool; Citrulline; Female; Humans; Infant; Infant, Newborn; Phenylacetates | 1993 |
Arginine utilization by Mycoplasma fermentans is not regulated by glucose metabolism: a 13C-NMR study.
Topics: Arginine; Citrulline; Glucose; Glycolysis; Hydrolases; Hydrolysis; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Mycoplasma fermentans | 1993 |
Conditions required for the measurement of nitric oxide synthase activity in a myenteric plexus/smooth muscle preparation from the rat ileum.
Topics: Animals; Antioxidants; Arginine; Biopterins; Calcium; Calmodulin; Citrulline; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Ileum; In Vitro Techniques; Muscle, Smooth; Myenteric Plexus; NADP; Nitric Oxide Synthase; Rats; Rats, Wistar | 1995 |
Structural probing and damage selection of citrulline- and arginine-specific RNA aptamers identify base positions required for binding.
Topics: Arginine; Base Sequence; Binding Sites; Citrulline; Lead; Magnesium; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Protein Structure, Secondary; RNA; Sequence Analysis, RNA | 1995 |
Recycling of L-citrulline to sustain nitric oxide-dependent enteric neurotransmission.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Citrulline; Colon; Dogs; Electrophysiology; Enteric Nervous System; Enzyme Inhibitors; Female; Immunohistochemistry; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Synaptic Transmission | 1995 |
Urea synthesis in enterocytes of developing pigs.
Topics: Ammonia; Ammonium Chloride; Animals; Animals, Newborn; Animals, Suckling; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbamoyl-Phosphate Synthase (Ammonia); Carbamyl Phosphate; Chromatography, High Pressure Liquid; Citrulline; Glutamine; Intestinal Mucosa; Intestines; Ornithine; Ornithine Carbamoyltransferase; Swine; Urea; Weaning | 1995 |
Determination of Km for oxygen of nitric oxide synthase isoforms.
Topics: Animals; Aorta; Arginine; Brain; Cattle; Cells, Cultured; Citrulline; Endothelium, Vascular; Isoenzymes; Kinetics; Macrophages; Mice; Nitric Oxide Synthase; Oxygen; Tritium | 1996 |
Inactivation of nitric oxide synthase isoforms by diaminoguanidine and NG-amino-L-arginine.
Topics: Animals; Arginine; Cattle; Citrulline; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Isoenzymes; Methylguanidine; Mice; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitric Oxide Synthase; Oxidation-Reduction; Rats | 1996 |
Stimulation of nitric oxide synthase by endothelial purinoceptors does not correlate with inositol trisphosphate levels.
Topics: Adenosine Triphosphate; Animals; Arginine; Cattle; Citrulline; Endothelium, Vascular; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Nitric Oxide Synthase; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Tetradecanoylphorbol Acetate; Uridine Triphosphate | 1995 |
Inhaled nitric oxide does not alter endotoxin-induced nitric oxide synthase activity during rat lung perfusion.
Topics: Administration, Inhalation; Animals; Arginine; Citrulline; Endotoxins; Feedback; In Vitro Techniques; Lung; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Perfusion; Rats; Rats, Sprague-Dawley | 1995 |
Nitric oxide synthase activity in the molluscan CNS.
Topics: Animals; Aplysia; Arginine; Calcium; Central Nervous System; Citrulline; Histocytochemistry; Mollusca; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats | 1996 |
Characterization of heme-deficient neuronal nitric-oxide synthase reveals a role for heme in subunit dimerization and binding of the amino acid substrate and tetrahydrobiopterin.
Topics: Animals; Arginine; Binding Sites; Biopterins; Brain; Chromatography, Gel; Circular Dichroism; Citrulline; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Heme; Isoenzymes; Light; Macromolecular Substances; Neurons; Nitric Oxide Synthase; Nitroarginine; Protein Conformation; Protein Structure, Secondary; Rats; Scattering, Radiation; Thermodynamics | 1996 |
Inhibition of cerebral neurogenic vasodilation by L-glutamine and nitric oxide synthase inhibitors and its reversal by L-citrulline.
Topics: Animals; Arginine; Cerebral Arteries; Citrulline; Enzyme Inhibitors; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Swine; Vasodilation | 1996 |
Nitric oxide synthase content of hypothalamic explants: increase by norepinephrine and inactivated by NO and cGMP.
Topics: Animals; Arginine; Carbon Radioisotopes; Citrulline; Cyclic GMP; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Kinetics; Male; Models, Neurological; Nerve Fibers; Neurons; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; Organ Culture Techniques; Rats; Rats, Wistar | 1996 |
Effects of estrogen on nitric oxide biosynthesis and vasorelaxant activity in sheep uterine and renal arteries in vitro.
Topics: Analysis of Variance; Animals; Arginine; Arteries; Bradykinin; Citrulline; Enzyme Inhibitors; Estradiol; Female; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Renal Artery; Sheep; Superoxide Dismutase; Uterus; Vasodilation | 1996 |
Evidence for VIP-induced increase in NO production in myenteric neurons of opossum internal anal sphincter.
Topics: Anal Canal; Animals; Arginine; Cells, Cultured; Citrulline; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglia, Autonomic; In Vitro Techniques; Kinetics; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Opossums; Peptide PHI; Tetrodotoxin; Vasoactive Intestinal Peptide | 1996 |
Nitric oxide synthase activity and non-adrenergic non-cholinergic relaxation in the rat gastric fundus.
Topics: Animals; Arginine; Atropine; Citrulline; Dose-Response Relationship, Drug; Electric Stimulation; Female; Gastric Fundus; Guanethidine; In Vitro Techniques; Isotonic Solutions; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Serotonin; Tetrodotoxin | 1996 |
Supplemental L-arginine HCl augments bacterial phagocytosis in human polymorphonuclear leukocytes.
Topics: Arginine; Cells, Cultured; Citrulline; Enzyme Inhibitors; Flow Cytometry; Humans; Microscopy, Fluorescence; Neutrophils; Nitric Oxide Synthase; Phagocytosis; Staphylococcus aureus | 1996 |
Interleukin-1 beta specifically stimulates nitric oxide production in the hypothalamus.
Topics: Animals; Arginine; Cells, Cultured; Chromatography, High Pressure Liquid; Citrulline; Enzyme Inhibitors; Hypothalamus; Interleukin-1; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats | 1996 |
Structural basis of ligand discrimination by two related RNA aptamers resolved by NMR spectroscopy.
Topics: Arginine; Base Composition; Base Sequence; Citrulline; Crystallography, X-Ray; Hydrogen Bonding; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; RNA | 1996 |
Protection against hepatic ischemia/reperfusion injury by exogenous L-arginine.
Topics: Animals; Arginine; Citrulline; Cyclic GMP; Liver; Liver Circulation; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion; Reperfusion Injury | 1996 |
Overexpression of neuronal nitric oxide synthase in insect cells reveals requirement of haem for tetrahydrobiopterin binding.
Topics: Animals; Arginine; Baculoviridae; Biopterins; Brain; Citrulline; Culture Media; Flavins; Heme; Kinetics; Neurons; Nitric Oxide Synthase; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Spodoptera; Tritium | 1996 |
Acute multiple sclerosis (Marburg type) is associated with developmentally immature myelin basic protein.
Topics: Adult; Antibodies, Monoclonal; Arginine; Blotting, Western; Brain; Brain Chemistry; Chronic Disease; Citrulline; Demyelinating Diseases; Fatal Outcome; Female; Humans; Lymphocytes; Macrophages; Magnetic Resonance Imaging; Multiple Sclerosis; Myelin Basic Protein | 1996 |
Calcium-dependent nitric oxide synthesis is potently stimulated by tetrahydrobiopterin in human primordial placenta.
Topics: Arginine; Biopterins; Calcium; Citrulline; Enzyme Activation; Female; Humans; NADP; Nitric Oxide; Nitric Oxide Synthase; Placenta; Pregnancy | 1996 |
Central antinociceptive effect of L-ornithine, a metabolite of L-arginine, in rats and mice.
Topics: Analgesia; Animals; Arginine; Carrageenan; Citrulline; Dipeptides; Dose-Response Relationship, Drug; Excipients; Hyperalgesia; Injections, Intraventricular; Leucine; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Ornithine; Pain Measurement; Protease Inhibitors; Rats | 1996 |
Cryptogenic hepatitis masking the diagnosis of ornithine transcarbamylase deficiency.
Topics: Absorption; Ammonia; Arginine; Child, Preschool; Citrulline; Diagnosis, Differential; Dietary Proteins; Female; Glutamine; Hepatitis; Humans; Infant; Lysine; Ornithine; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Urea | 1996 |
Changes in the release of amino acid neurotransmitters in the brains of calves and sheep after head-only electrical stunning and throat cutting.
Topics: Abattoirs; Amino Acids; Animals; Arginine; Aspartic Acid; Brain; Cattle; Citrulline; Electroencephalography; Electroshock; gamma-Aminobutyric Acid; Glycine; Neurotransmitter Agents; Ornithine; Postmortem Changes; Sheep; Taurine | 1996 |
Therapeutic use of carbamylglutamate in the case of carbamoyl-phosphate synthetase deficiency.
Topics: Ammonia; Arginine; Carbamoyl-Phosphate Synthase (Ammonia); Child, Preschool; Citrulline; Glutamates; Glutamic Acid; Glutamine; Humans; Male | 1996 |
Stimulation-induced 3H-L-citrulline accumulation in isolated longitudinal muscle myenteric plexus preparations of rat small intestine: a measure to characterize nitrergic neurons.
Topics: Animals; Arginine; Calcimycin; Citrulline; Electric Stimulation; In Vitro Techniques; Intestine, Small; Muscarinic Antagonists; Muscle, Smooth; Myenteric Plexus; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Scopolamine; Tritium | 1995 |
Barium activates rat cerebellar nitric oxide synthase.
Topics: Animals; Arginine; Barium; Calcium; Calmodulin; Cerebellum; Chromatography, Ion Exchange; Citrulline; Cyclic GMP; Enzyme Activation; Lethal Dose 50; Male; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1996 |
Nitric oxide synthase inhibitors: amino acids.
Topics: Amino Acids; Animals; Arginine; Citrulline; Enzyme Inhibitors; Isoenzymes; Kinetics; Macrophages; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rodentia; Structure-Activity Relationship; Thiourea | 1996 |
Binding of intermediate, product, and substrate analogs to neuronal nitric oxide synthase: ferriheme is sensitive to ligand-specific effects in the L-arginine binding site.
Topics: Animals; Arginine; Binding Sites; Cell Line; Citrulline; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Heme; Kidney; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Rats | 1996 |
Inhibition of nitric oxide synthase isoforms by porphyrins.
Topics: Animals; Arginine; Cattle; Cell Line; Citrulline; Enzyme Inhibitors; Humans; In Vitro Techniques; Interferon-gamma; Isoenzymes; Kinetics; Mice; Molecular Structure; NADH Dehydrogenase; NADPH Oxidases; Nitric Oxide Synthase; Porphyrins; Protoporphyrins; Rats | 1996 |
Systemic and fetal-maternal nitric oxide synthesis in normal pregnancy and pre-eclampsia.
Topics: Adult; Arginine; Blood Platelets; Blotting, Northern; Citrulline; Cyclic GMP; Female; Humans; Nitric Oxide; Nitric Oxide Synthase; Pre-Eclampsia; Pregnancy | 1996 |
Neural barriers affect the action of nitric oxide synthase inhibitors in the intact chicken retina.
Topics: Animals; Arginine; Blood-Retinal Barrier; Chickens; Citrulline; Enzyme Inhibitors; In Vitro Techniques; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Pigment Epithelium of Eye; Retina | 1995 |
Calcium-independent and steroid-resistant nitric oxide synthase activity in human paranasal sinus mucosa.
Topics: Adult; Arginine; Betamethasone; Calcium; Case-Control Studies; Citrulline; Female; Glucocorticoids; Humans; Male; Maxillary Sinus; Middle Aged; Nasal Mucosa; Nitric Oxide; Nitric Oxide Synthase; RNA, Messenger | 1996 |
Citrulline and arginine increase the growth of the Ward colon tumor in parenterally fed rats.
Topics: Animals; Arginine; Citrulline; Colonic Neoplasms; Glutamine; Male; Ornithine; Parenteral Nutrition; Rats; Rats, Inbred F344; Taurine; Urea | 1996 |
An unique model for the analysis of neuronal nitric oxide signaling: the leech CNS.
Topics: Animals; Arginine; Central Nervous System; Citrulline; Ganglia, Invertebrate; Histocytochemistry; Leeches; Models, Neurological; NADPH Dehydrogenase; Neurons; Nitric Oxide; Nitric Oxide Synthase; Rats; Signal Transduction; Species Specificity; Synapses | 1995 |
Influence of glutamine-supplemented parenteral nutrition on intestinal amino acid metabolism in rats after small bowel resection.
Topics: Amino Acids; Animals; Arginine; Citrulline; Glutamine; Intestinal Mucosa; Intestine, Small; Male; Parenteral Nutrition, Total; Rats; Rats, Sprague-Dawley; Short Bowel Syndrome | 1996 |
Vasodilation by intrathecal lipopolysaccharide of the cerebral arteries after subarachnoid haemorrhage in dogs.
Topics: Analysis of Variance; Angiography; Animals; Arginine; Basilar Artery; Bradykinin; Citrulline; Cytokines; Dogs; Enzyme Inhibitors; Female; Injections, Spinal; Lipopolysaccharides; Male; Microscopy, Electron; Nitric Oxide Synthase; omega-N-Methylarginine; Subarachnoid Hemorrhage; Vasoconstrictor Agents; Vasodilation; Vasopressins | 1996 |
Arginine metabolism in cat kidney.
Topics: Animals; Arginine; Cats; Citrulline; Female; Kidney; Male; Mice; Rabbits; Rats; Rats, Sprague-Dawley; Urea | 1996 |
Anticonvulsant effects of 7-nitroindazole in rodents with reflex epilepsy may result from L-arginine accumulation or a reduction in nitric oxide or L-citrulline formation.
Topics: Animals; Anticonvulsants; Arginine; Blood Pressure; Citrulline; Disease Models, Animal; Epilepsy; Female; Heart Rate; Indazoles; Male; Mice; Mice, Inbred DBA; Motor Activity; Nitric Oxide; Nitric Oxide Synthase; Noise; Rats; Rats, Inbred Strains; Reflex; Seizures | 1996 |
Whole body nitric oxide synthesis in healthy men determined from [15N] arginine-to-[15N]citrulline labeling.
Topics: Adult; Arginine; Citrulline; Eating; Fasting; Humans; Isotope Labeling; Male; Models, Biological; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes; Time Factors | 1996 |
Metabolism of arginine to citrulline by rat gastric mucosal cells.
Topics: Animals; Arginase; Arginine; Citrulline; Gastric Mucosa; In Vitro Techniques; Nitric Oxide Synthase; Ornithine; Rats | 1996 |
Conditions altering plasma concentrations of urea cycle and other amino acids in elderly human subjects.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amino Acids; Arginine; Citrulline; Cohort Studies; Data Collection; Dietary Proteins; Eating; Energy Intake; Fasting; Female; Humans; Middle Aged; Nitrates; Ornithine; Postmenopause; Regression Analysis; Time Factors | 1996 |
Protein unfolding by peptidylarginine deiminase. Substrate specificity and structural relationships of the natural substrates trichohyalin and filaggrin.
Topics: Amino Acid Sequence; Animals; Arginine; Circular Dichroism; Citrulline; Filaggrin Proteins; Humans; Hydrolases; Intermediate Filament Proteins; Mice; Molecular Sequence Data; Peptides; Protein Denaturation; Protein Precursors; Protein Structure, Secondary; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Skin; Spectrometry, Fluorescence; Substrate Specificity | 1996 |
Arginine degradation in developing porcine enterocytes.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Aging; Animals; Animals, Newborn; Animals, Suckling; Arginine; Cells, Cultured; Citrulline; Cyclohexanecarboxylic Acids; Intestinal Mucosa; Jejunum; Nitric Oxide Synthase; Nitroarginine; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Proline; Pyrroline Carboxylate Reductases; Swine; Valine; Weaning | 1996 |
Arginase activity in endothelial cells: inhibition by NG-hydroxy-L-arginine during high-output NO production.
Topics: Animals; Arginase; Arginine; Cells, Cultured; Citrulline; Endothelium, Vascular; Enzyme Induction; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Urea | 1996 |
An important role for endogenous synthesis of arginine in maintaining arginine homeostasis in neonatal pigs.
Topics: Administration, Oral; Amino Acids; Animals; Animals, Newborn; Arginine; Citrulline; Cyclohexanecarboxylic Acids; Glutamine; Homeostasis; Intestinal Mucosa; Intestines; Muscle, Skeletal; Ornithine; Ornithine-Oxo-Acid Transaminase; Pyrroles; Swine | 1996 |
P2 purinoceptor-stimulated conversion of arginine to citrulline in bovine endothelial cells is reduced by inhibition of protein kinase C.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Citrulline; Endothelium, Vascular; Nitric Oxide; Nitric Oxide Synthase; Protein Kinase C; Receptors, Purinergic P2; Tetradecanoylphorbol Acetate | 1996 |
Presence of nitric oxide synthase activity in roots and nodules of Lupinus albus.
Topics: Arginine; Citrulline; Enzyme Inhibitors; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plant Roots; Plants; Rhizobiaceae | 1996 |
Clinical and biochemical heterogeneity in females of a large pedigree with ornithine transcarbamylase deficiency due to the R141Q mutation.
Topics: Allopurinol; Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Citrulline; Female; Glutamine; Heterozygote; Humans; Infant, Newborn; Male; Mutation; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Pedigree | 1996 |
Quantitative aspects of interorgan relationships among arginine and citrulline metabolism.
Topics: Animals; Arginine; Citrulline; Dogs; Male; Organ Specificity | 1996 |
Inducible nitric oxide synthase in rat brown adipocytes: implications for blood flow to brown adipose tissue.
Topics: Adipocytes; Adipose Tissue, Brown; Animals; Arginine; Cells, Cultured; Citrulline; Dactinomycin; Enzyme Induction; Enzyme Inhibitors; Kinetics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Norepinephrine; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 1997 |
Bacterial infection induces nitric oxide synthase in human neutrophils.
Topics: Adult; Aged; Anti-Bacterial Agents; Arginine; Bacterial Infections; Blotting, Western; Canavanine; Cell Membrane; Citrulline; Female; Guanidines; Humans; Immunohistochemistry; Isoenzymes; Leukocyte Common Antigens; Male; Middle Aged; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thiourea; Trifluoperazine; Urinary Tract Infections | 1997 |
Mechanisms involved in the effect of nitric oxide synthase inhibition on L-arginine-induced insulin secretion.
Topics: Animals; Arginase; Arginine; Citrulline; Enzyme Inhibitors; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Wistar; Vasodilator Agents | 1997 |
Regulation of citrulline recycling in nitric oxide-dependent neurotransmission in the murine proximal colon.
Topics: Animals; Arginine; Citrulline; Colon; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Substrate Cycling; Synaptic Transmission; Thiourea | 1997 |
Diabetes and insulin-induced stimulation of L-arginine transport and nitric oxide synthesis in rabbit isolated gastric glands.
Topics: Animals; Arginine; Citrulline; Cyclic GMP; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Exocrine Glands; Gastric Mucosa; Hypoglycemic Agents; Insulin; Kinetics; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rabbits | 1997 |
[3H]L-arginine transport and nitric oxide synthase activity in foetal hypothalamic cultures.
Topics: Amino Acid Transport Systems; Animals; Arginine; Biological Transport; Carrier Proteins; Cells, Cultured; Citrulline; Enzyme Inhibitors; Hypothalamus; Neuroglia; Neurons; Nitric Oxide Synthase; Ornithine; Rats | 1996 |
Differences in nitric oxide synthase activity in a macrophage-like cell line, RAW264.7 cells, treated with lipopolysaccharide (LPS) in the presence or absence of interferon-gamma (IFN-gamma): possible heterogeneity of iNOS activity.
Topics: Animals; Arginine; Benzoates; Carbon Radioisotopes; Cell Line; Chromatography, Thin Layer; Citrulline; Dose-Response Relationship, Drug; Enzyme Activation; Imidazoles; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; NADP; Nitric Oxide Synthase; Substrate Specificity; Time Factors | 1997 |
Activation of nitric oxide synthase by ischaemia in the perfused heart.
Topics: Animals; Arginine; Cell Membrane; Citrulline; Cytosol; Enzyme Activation; In Vitro Techniques; Isoenzymes; Male; Myocardial Ischemia; Nitric Oxide Synthase; Perfusion; Rabbits | 1997 |
Inhalational anesthetic effects on rat cerebellar nitric oxide and cyclic guanosine monophosphate production.
Topics: Anesthetics, Inhalation; Animals; Arginine; Cerebellum; Citrulline; Cyclic GMP; Drug Interactions; Excitatory Amino Acid Agonists; Halothane; Isoflurane; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Tritium | 1997 |
Effect of tirilazad on brain nitric oxide synthase activity during cerebral ischemia in rats.
Topics: Animals; Arginine; Brain; Citrulline; Enzyme Inhibitors; Ischemic Attack, Transient; Kinetics; Male; Neuroprotective Agents; Nitric Oxide Synthase; Pregnatrienes; Rats; Rats, Wistar | 1997 |
L-citrulline recycling in opossum internal anal sphincter relaxation by nonadrenergic, noncholinergic nerve stimulation.
Topics: Anal Canal; Animals; Arginine; Citrulline; Electric Stimulation; Enzyme Inhibitors; Female; Glutamine; Male; Muscle Relaxation; Muscle Tonus; Nervous System Physiological Phenomena; Nitroarginine; Opossums; Time Factors | 1997 |
Neuronal nitric oxide reduces sympathetic excitability by modulation of central glutamate effects in pigs.
Topics: Animals; Arginine; Brain Stem; Citrulline; Enzyme Inhibitors; Glutamic Acid; Heart Rate; Hemodynamics; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Swine; Sympathetic Nervous System; Thiourea; Vagotomy | 1997 |
L-arginine infusion increases basal but not activated cerebral blood flow in humans.
Topics: Adult; Arginine; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Citrulline; Deuterium Oxide; Female; Human Growth Hormone; Humans; Hydrogen-Ion Concentration; Insulin; Male; Nitric Oxide; Partial Pressure; Stimulation, Chemical; Subtraction Technique; Tomography, Emission-Computed; Touch; Vasodilator Agents; Vibration | 1997 |
Differential regulation of macrophage arginine metabolism: a proposed role in wound healing.
Topics: Amino Acids; Animals; Arginase; Arginine; Cells, Cultured; Citrulline; Exudates and Transudates; Female; Hybridization, Genetic; Hydrogen-Ion Concentration; Intracellular Membranes; Macrophages; Mice; Mice, Inbred Strains; Nitric Oxide; Osmolar Concentration; Peritoneum; Wound Healing | 1997 |
Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin.
Topics: Animals; Arginine; Calmodulin; Cerebellum; Citrulline; Cyclic GMP; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Kinetics; Male; Melatonin; Nitric Oxide Synthase; Rats; Rats, Wistar | 1997 |
Mechanism of nitric oxide production induced by H2O2 in cultured endothelial cells.
Topics: Aniline Compounds; Animals; Aorta, Thoracic; Arginine; Calcium; Catalase; Cattle; Cell Fractionation; Cells, Cultured; Citrulline; Dose-Response Relationship, Drug; Endothelium, Vascular; Fluorescent Dyes; Hydrogen Peroxide; Ionomycin; Ionophores; Isotope Labeling; Microscopy, Confocal; Nitric Oxide; Oxidants; Tritium; Xanthenes | 1997 |
Nitric oxide synthase and arginase in cells isolated from the rat gastric mucosa.
Topics: Animals; Arginase; Arginine; Cell Separation; Citrulline; Gastric Mucosa; Immunoblotting; Immunohistochemistry; Nitric Oxide Synthase; Rats | 1997 |
Biogenesis of Candida albicans Can1 permease expressed in Saccharomyces cerevisiae.
Topics: Amino Acid Transport Systems; Ammonia; Arginine; Blotting, Western; Candida albicans; Citrulline; Cycloheximide; Epitopes; Fungal Proteins; Gene Expression; Histidine; Lysine; Membrane Transport Proteins; Mutation; Plasmids; Proline; Proto-Oncogene Proteins c-myc; Recombinant Proteins; Saccharomyces cerevisiae; Transformation, Genetic | 1997 |
Substituted N-phenylisothioureas: potent inhibitors of human nitric oxide synthase with neuronal isoform selectivity.
Topics: Animals; Arginine; Binding, Competitive; Brain; Citrulline; Enzyme Inhibitors; Humans; Isoenzymes; Molecular Structure; Neurons; Nitric Oxide Synthase; Rats; Structure-Activity Relationship; Thiourea | 1997 |
Immunohistochemical localization of arginine and citrulline in rat renal tissue.
Topics: Animals; Arginine; Citrulline; Epithelium; Immunohistochemistry; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules, Proximal; Male; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1997 |
Citrulline-argininosuccinate-arginine cycle coupled to Ca2+-signaling in rat pancreatic beta-cells.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Argininosuccinic Acid; Calcium; Cells, Cultured; Citrulline; Cytosol; Immunohistochemistry; Insulinoma; Islets of Langerhans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pancreatic Neoplasms; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Regulation of cerebellar nitric oxide production in response to prolonged in vivo hypoxia.
Topics: Animals; Arginine; Argininosuccinate Lyase; Biopterins; Cerebellum; Citrulline; Endothelium, Vascular; Enzyme Induction; GTP Cyclohydrolase; Hypoxia, Brain; Isoenzymes; Male; Nerve Tissue Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1997 |
The role of nitric oxide in the pathophysiology of thromboembolic stroke in the rat.
Topics: Animals; Arginine; Behavior, Animal; Blood Pressure; Cerebrovascular Disorders; Citrulline; Cognition Disorders; Enzyme Inhibitors; Intracranial Embolism and Thrombosis; Male; Motor Cortex; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Somatosensory Cortex; Thromboembolism | 1997 |
L-arginine deficiency causes suppression of nonadrenergic noncholinergic nerve-mediated smooth muscle relaxation: role of L-citrulline recycling.
Topics: Anal Canal; Animals; Arginase; Arginine; Citrulline; Electric Stimulation; Female; Glutamine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Opossums | 1997 |
Role of exogenous L-arginine in hepatic ischemia-reperfusion injury.
Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Citrulline; Cyclic GMP; Female; Hemodynamics; Liver; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Reperfusion Injury; Swine; Time Factors | 1997 |
Synthesis of citrulline and arginine from proline in enterocytes of postnatal pigs.
Topics: Aging; Animals; Animals, Newborn; Arginine; Carbon Radioisotopes; Citrulline; Female; Intestinal Mucosa; Male; Mitochondria; Models, Biological; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Radioisotope Dilution Technique; Rats; Swine | 1997 |
Altered wound arginine metabolism by corticosterone and retinoic acid.
Topics: Animals; Arginase; Arginine; Citrulline; Corticosterone; Male; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley; Tretinoin; Wound Healing; Wounds and Injuries | 1997 |
On the unidirectionality of arginine uptake in the yeast Saccharomyces cerevisiae.
Topics: Amino Acid Transport Systems; Arginine; Biological Transport; Citrulline; Fungal Proteins; Genes, Fungal; Lysine; Membrane Transport Proteins; Saccharomyces cerevisiae | 1997 |
Post-transcriptional regulation of inducible nitric oxide synthase mRNA in murine macrophages by doxycycline and chemically modified tetracyclines.
Topics: Animals; Arginine; Citrulline; Doxycycline; Hydrocortisone; Macrophages; Mice; Minocycline; Molecular Structure; Nitric Oxide Synthase; Nitrites; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetracyclines | 1997 |
Identification of nitric oxide synthase in human and bovine oviduct.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Citrulline; Epithelial Cells; Epithelium; Fallopian Tubes; Female; Humans; In Vitro Techniques; NADPH Dehydrogenase; Nitrates; Nitric Oxide Synthase; Nitrites | 1996 |
Endogenously produced nitric oxide increases tumor necrosis factor-alpha production in transfected human U937 cells.
Topics: Animals; Arginine; Cell Differentiation; Citrulline; Cyclic GMP; DNA, Complementary; Enzyme Induction; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Lymphoma, Large B-Cell, Diffuse; Mice; Neoplasm Proteins; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Recombinant Fusion Proteins; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Interleukin 1beta-mediated inhibition of arginase in RINm5F cells.
Topics: Animals; Arginase; Arginine; Citrulline; Enzyme Inhibitors; Glutathione; Insulinoma; Interleukin-1; Islets of Langerhans; Molsidomine; Nitric Oxide Synthase; Nitroso Compounds; Ornithine; Rats; S-Nitrosoglutathione; Tumor Cells, Cultured | 1997 |
The nitric oxide synthase of mouse spermatozoa.
Topics: Animals; Antibodies; Arginine; Carbon Radioisotopes; Citrulline; Female; Immunoblotting; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nitric Oxide; Nitric Oxide Synthase; Spermatozoa | 1997 |
Role of L-arginine, a substrate for nitric oxide-synthase, in gastroprotection and ulcer healing.
Topics: Animals; Arginine; Capsaicin; Citrulline; Dose-Response Relationship, Drug; Endothelium; Gastric Acid; Gastric Mucosa; Glutamine; Immunohistochemistry; Indomethacin; Male; Neovascularization, Pathologic; Neurons, Afferent; Nitroarginine; Ornithine; Pepsin A; Rats; Rats, Wistar; Ulcer | 1997 |
Adrenal control of erectile function and nitric oxide synthase in the rat penis.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Arginine; Citrulline; Dihydrotestosterone; Hydrocortisone; Male; Nitric Oxide Synthase; Orchiectomy; Penile Erection; Penis; Rats; Rats, Inbred F344 | 1997 |
[Measurement of NOS activity by monitoring the conversion of 3H-arginine].
Topics: Animals; Arginine; Chromatography, Affinity; Citrulline; Female; Male; Nitric Oxide Synthase; Rats; Rats, Wistar | 1996 |
Reduction of placental nitric oxide synthase activity in pre-eclampsia.
Topics: Arginine; Citrulline; Culture Techniques; Female; Humans; Nitric Oxide Synthase; Obstetric Labor, Premature; Placenta; Pre-Eclampsia; Pregnancy | 1997 |
Morphologic evidence for L-citrulline conversion to L-arginine via the argininosuccinate pathway in porcine cerebral perivascular nerves.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Cerebral Arteries; Citrulline; Microscopy, Electron; Nerve Fibers; Swine | 1997 |
Arginine metabolism in keratinocytes and macrophages during nitric oxide biosynthesis: multiple modes of action of nitric oxide synthase inhibitors.
Topics: Animals; Arginine; Cell Line; Citrulline; Dose-Response Relationship, Drug; Guanidines; Interferon-gamma; Keratinocytes; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Tumor Cells, Cultured | 1997 |
Inhibition of NO synthase induction by an anticancer drug 4'-epi-doxorubicin in rats.
Topics: Acetylcholine; Animals; Antibiotics, Antineoplastic; Aorta, Thoracic; Arginine; Cerebellum; Citrulline; Endothelium, Vascular; Enzyme Induction; Epirubicin; In Vitro Techniques; Lipopolysaccharides; Lung; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Wistar | 1996 |
Ketamine inhibits nitric oxide synthase in lipopolysaccharide-treated rat alveolar macrophages.
Topics: Analysis of Variance; Anesthetics, Dissociative; Animals; Arginine; Blotting, Western; Cell Respiration; Cell Survival; Cells, Cultured; Citrulline; Culture Media; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Enzymologic; Ketamine; Lipopolysaccharides; Macrophages, Alveolar; Male; Nitric Oxide Synthase; Nitrites; Radiopharmaceuticals; Rats; Rats, Inbred WKY; Tritium; Tumor Necrosis Factor-alpha | 1997 |
Analysis of neuronal NO synthase under single-turnover conditions: conversion of Nomega-hydroxyarginine to nitric oxide and citrulline.
Topics: Animals; Arginine; Citrulline; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase | 1997 |
No increase of ornithine concentration in the liver of ornithine transcarbamylase-deficient spf-ash mice following intraperitoneal injection of ammonium chloride.
Topics: Ammonia; Ammonium Chloride; Animals; Arginine; Citrulline; Liver; Mice; Mice, Inbred Strains; Mice, Transgenic; Ornithine; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Peptones | 1997 |
Post-hypoxic hypothermia reduces cerebrocortical release of NO and excitotoxins.
Topics: Animals; Arginine; Cerebral Cortex; Citrulline; Electroencephalography; Excitatory Amino Acids; Hypothermia; Hypoxia, Brain; Microdialysis; Nitric Oxide; Swine | 1997 |
Orthotopic liver transplantation for adult-onset type II citrullinaemia.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Ammonia; Arginine; Argininosuccinate Synthase; Brain Edema; Cause of Death; Citrulline; Diet, Protein-Restricted; Disease Progression; Fatal Outcome; Glutamic Acid; Hepatic Encephalopathy; Humans; Immunohistochemistry; Liver; Liver Transplantation; Male; Prognosis; Referral and Consultation | 1997 |
L-citrulline conversion to L-arginine in sphenopalatine ganglia and cerebral perivascular nerves in the pig.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Cerebral Arteries; Cerebral Veins; Citrulline; Dihydrolipoamide Dehydrogenase; Electric Stimulation; Ganglia, Parasympathetic; Nerve Fibers; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pia Mater; Swine | 1997 |
Activation of brain nitric oxide synthase in depolarized human temporal cortex slices: differential role of voltage-sensitive calcium channels.
Topics: Alanine; Arginine; Calcium Channel Blockers; Calcium Channels; Citrulline; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; In Vitro Techniques; Mecamylamine; Nicotinic Antagonists; Nitric Oxide Synthase; Nitroarginine; Potassium; Potassium Chloride; Quinoxalines; Temporal Lobe | 1997 |
Changes in nitric oxide synthase activity during exposure to hydrogen peroxide in cultured endothelial cells.
Topics: Animals; Arginine; Cattle; Cell Death; Cells, Cultured; Citrulline; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; Ionomycin; Ionophores; L-Lactate Dehydrogenase; Nitric Oxide Synthase | 1997 |
Formation of N delta-cyanoornithine from NG-hydroxy-L-arginine and hydrogen peroxide by neuronal nitric oxide synthase: implications for mechanism.
Topics: Animals; Arginine; Cell Line; Chromatography, High Pressure Liquid; Citrulline; Hydrogen Peroxide; Kinetics; Mass Spectrometry; Models, Chemical; Neurons; Nitric Oxide Synthase; Ornithine; Recombinant Proteins; Spodoptera; Substrate Specificity; Transfection | 1997 |
Determination of nitric oxide synthase activity in rat, pig and rabbit prostate glands.
Topics: Animals; Arginase; Arginine; Calcium; Citrulline; Enzyme Inhibitors; Male; Nitric Oxide Synthase; Nitroarginine; Prostate; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity; Swine | 1997 |
Effect of chronic administration of [D-Pen2, D-Pen5] enkephalin on the activity of nitric oxide synthase in brain regions and spinal cord of mice.
Topics: Analgesics; Animals; Arginine; Brain; Citrulline; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Nitric Oxide Synthase; Pain Measurement; Receptors, Opioid, delta; Spinal Cord | 1998 |
Effects of ATP, ADP, thrombin, vasopressin and U46619 on human placental nitric oxide synthase activity.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Arginine; Chromatography, Thin Layer; Citrulline; Female; Hemostatics; Humans; In Vitro Techniques; Nitric Oxide Synthase; Nitroarginine; Placenta; Thrombin; Vasoconstrictor Agents; Vasopressins | 1997 |
Substrate inhibition of nitric oxide synthase in pulmonary artery endothelial cells in culture.
Topics: Animals; Arginine; Benzoates; Cell Membrane; Cells, Cultured; Citrulline; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Oxyhemoglobins; Pulmonary Artery; Superoxide Dismutase; Swine | 1997 |
NADPH-diaphorase-stained neurons after experimental epilepsy in rats.
Topics: Animals; Arginine; Behavior, Animal; Brain; Citrulline; Electric Stimulation; Electrophysiology; Epilepsy, Generalized; Glutamic Acid; Histocytochemistry; Image Processing, Computer-Assisted; Kindling, Neurologic; Male; NADPH Dehydrogenase; Neurons; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar | 1997 |
Elevated D-glucose induces insulin insensitivity in human umbilical endothelial cells isolated from gestational diabetic pregnancies.
Topics: Amino Acids; Antimetabolites; Arginine; Calcium; Citrulline; Cyclic GMP; Deoxyglucose; Endothelium, Vascular; Epoprostenol; Female; Glucose; Humans; Insulin Resistance; Membrane Potentials; Onium Compounds; Organophosphorus Compounds; Pregnancy; Pregnancy in Diabetics; Umbilical Veins | 1998 |
Role of nitric oxide synthase inhibition in the acute hypertensive response to intracerebroventricular cadmium.
Topics: Animals; Arginine; Blood Pressure; Brain Chemistry; Cadmium; Calcium Chloride; Citrulline; Enzyme Inhibitors; Heart Rate; Hypertension; Injections, Intraventricular; Male; Molsidomine; Nitric Oxide Synthase; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1998 |
Neuronal NOS-cGMP-dependent ACh-induced relaxation in pial arterioles of endothelial NOS knockout mice.
Topics: Acetylcholine; Animals; Arginine; Arterioles; Autoradiography; Brain; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Indazoles; Mice; Mice, Knockout; Neurons; Nitric Oxide Synthase; Pia Mater; Quinuclidinyl Benzilate; Receptors, Muscarinic; Vasodilation | 1998 |
Selective deimination of vimentin in calcium ionophore-induced apoptosis of mouse peritoneal macrophages.
Topics: Animals; Apoptosis; Arginine; Blotting, Western; Calcium; Cell Nucleus; Citrulline; DNA Fragmentation; Fluorescent Antibody Technique; Hydrolases; Ionomycin; Ionophores; Kinetics; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Vimentin | 1998 |
Reduction of serum citrulline levels in women at term toward the day of labor onset.
Topics: Arginine; Citrulline; Cohort Studies; Female; Gestational Age; Humans; Labor, Obstetric; Nitric Oxide; Pregnancy | 1998 |
Changes in the concentrations of free amino acids in milk during growth of Lactococcus lactis indicate biphasic nitrogen metabolism.
Topics: Amino Acids; Animals; Arginine; Citrulline; Hydrogen-Ion Concentration; Hydrolases; Lactococcus lactis; Milk; Nitrogen; Ornithine | 1998 |
Structure of nitric oxide synthase oxygenase dimer with pterin and substrate.
Topics: Animals; Arginine; Binding Sites; Biopterins; Citrulline; Crystallography, X-Ray; Dimerization; Hydrogen Bonding; Isoenzymes; Ligands; Macrophages; Mice; Models, Molecular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Conformation; Protein Folding; Protein Structure, Secondary; Thiourea | 1998 |
Characterization of Cyprinus carpio brain nitric oxide synthase.
Topics: Animals; Arginine; Brain; Brain Chemistry; Carps; Citrulline; Enzyme Inhibitors; Free Radicals; Indazoles; Male; Nitric Oxide Synthase; Rats; Rats, Wistar; Species Specificity; Tritium | 1998 |
L-arginine inhibits smooth muscle cell proliferation of vein graft intimal thickness in hypercholesterolemic rabbits.
Topics: Acetylcholine; Analysis of Variance; Animals; Arginine; Bromodeoxyuridine; Cell Division; Citrulline; Graft Rejection; Hypercholesterolemia; In Vitro Techniques; Jugular Veins; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Rabbits; Tunica Intima | 1997 |
Arginine-metabolizing enzymes in the developing rat small intestine.
Topics: Animals; Animals, Newborn; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Blotting, Northern; Carbamoyl-Phosphate Synthase (Ammonia); Citrulline; Female; In Situ Hybridization; Intestine, Small; Male; Ornithine Carbamoyltransferase; Ornithine-Oxo-Acid Transaminase; Rats; Rats, Wistar; RNA, Messenger; Weaning | 1998 |
Effects of pH on the structure and function of neuronal nitric oxide synthase.
Topics: Animals; Arginine; Biopterins; Brain; Citrulline; Dimerization; Heme; Hydrogen Peroxide; Hydrogen-Ion Concentration; NADP; Nerve Tissue Proteins; Nitric Oxide Synthase; Protein Binding; Protein Conformation; Rats; Spectrophotometry | 1998 |
Myogenic NOS in canine lower esophageal sphincter: enzyme activation, substrate recycling, and product actions.
Topics: Animals; Arginine; Citrulline; Dogs; Electric Conductivity; Enzyme Activation; Esophagogastric Junction; Female; Male; Muscles; Nitric Oxide; Nitric Oxide Synthase | 1998 |
H2O2 causes endothelial barrier dysfunction without disrupting the arginine-nitric oxide pathway.
Topics: Animals; Arginine; Capillary Permeability; Cells, Cultured; Citrulline; Cyclic GMP; Endothelium, Vascular; Hydrogen Peroxide; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Pulmonary Artery; Swine | 1998 |
L-arginine produces NO-independent increases in dopamine efflux in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Arginine; Citrulline; Corpus Striatum; Dopamine; Enzyme Inhibitors; Homovanillic Acid; Indazoles; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Stereoisomerism | 1998 |
L-arginine binding to liver arginase requires proton transfer to gateway residue His141 and coordination of the guanidinium group to the dimanganese(II,II) center.
Topics: Animals; Arginase; Arginine; Asparagine; Binding Sites; Borates; Citrulline; Electron Spin Resonance Spectroscopy; Guanidine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Liver; Lysine; Manganese; Mutagenesis, Site-Directed; Ornithine; Protons; Rats; Substrate Specificity | 1998 |
Capillary electrophoresis analysis of nitric oxide synthase related metabolites in single identified neurons.
Topics: Animals; Aplysia; Arginine; Argininosuccinic Acid; Citrulline; Electrophoresis, Capillary; Mollusca; Nerve Tissue Proteins; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Organophosphorus Compounds; Ornithine | 1998 |
Nitric oxide downregulates tumour necrosis factor in mRNA in RAW 264.7 cells.
Topics: Animals; Arginine; Blotting, Northern; Cell Line; Citrulline; Dactinomycin; Down-Regulation; Kinetics; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1998 |
Substrate specificity of NO synthases: detailed comparison of L-arginine, homo-L-arginine, their N omega-hydroxy derivatives, and N omega-hydroxynor-L-arginine.
Topics: Animals; Arginine; Catalysis; Cattle; Citrulline; Homoarginine; Kinetics; NADP; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Oxygen; Substrate Specificity | 1998 |
Calcium-dependent nitric oxide synthase activity in rat thymocytes.
Topics: Animals; Arginine; Calcium; CD2 Antigens; Citrulline; Immunohistochemistry; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Wistar; T-Lymphocytes; Thymus Gland | 1998 |
Evidence for the presence of L-arginine-nitric oxide pathway in human red blood cells: relevance in the effects of red blood cells on platelet function.
Topics: Animals; Arginine; Blood Platelets; Blotting, Western; Citrulline; Enzyme Inhibitors; Erythrocytes; Humans; In Vitro Techniques; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Aggregation; Serotonin | 1998 |
Nitric oxide synthase activity in human renal cell carcinoma.
Topics: Analysis of Variance; Anticarcinogenic Agents; Arginine; Calcium; Carcinogens; Carcinoma, Renal Cell; Cell Division; Cells, Cultured; Citrulline; DNA; Enzyme Inhibitors; Humans; Interleukin-2; Kidney Neoplasms; Kidney Tubules, Proximal; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Thymidine; Tumor Cells, Cultured | 1998 |
The activation of eNOS by copper ion (Cu2+) in human pulmonary arterial endothelial cells (HPAEC).
Topics: Arginine; Calcium; Cations, Divalent; Cells, Cultured; Citrulline; Copper; Edetic Acid; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Luminescent Measurements; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Pulmonary Artery | 1998 |
Up-regulation of the neuronal form of nitric oxide synthase in response to prolonged muscarinic M1 receptor stimulation.
Topics: Animals; Arginine; Binding, Competitive; Calcium; Carbachol; CHO Cells; Citrulline; Cricetinae; Dose-Response Relationship, Drug; Humans; Ionomycin; Ionophores; Muscarinic Agonists; Nerve Tissue Proteins; Neuroblastoma; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Receptor, Muscarinic M1; Receptors, Muscarinic; Tritium; Tumor Cells, Cultured | 1998 |
Studies of arginine metabolism and salt sensitivity in the Dahl/Rapp rat models of hypertension.
Topics: Alanine; Animals; Arginine; Argininosuccinate Synthase; Blood Pressure; Body Weight; Citrulline; Disease Models, Animal; Hypertension; Kidney; Liver; Male; Ornithine; Rats; Sodium Chloride, Dietary; Urea | 1998 |
An improved assay for measurement of nitric oxide synthase activity in biological tissues.
Topics: Animals; Arginase; Arginine; Carbon Radioisotopes; Cell Fractionation; Chromatography, Ion Exchange; Citrulline; Cytosol; Enzyme Inhibitors; Female; In Vitro Techniques; Kinetics; Membranes; Methods; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley; Scintillation Counting | 1998 |
Proceedings of a satellite meeting on advances in inherited urea cycle disorders. Vienna, 20-21 May 1997.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Carbamoyl-Phosphate Synthase (Ammonia); Citrulline; Genetic Therapy; Genome, Human; Humans; Nitrogen; Ornithine Carbamoyltransferase Deficiency Disease; Urea | 1998 |
Evaluation of gene therapy for citrullinaemia using murine and bovine models.
Topics: Adenoviruses, Human; Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Arginine; Argininosuccinate Synthase; Benzoates; Benzoic Acid; Cattle; Citrulline; Disease Models, Animal; Evaluation Studies as Topic; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Liver; Mice; Nitrogen; Treatment Outcome; Urea | 1998 |
Factors contributing to differences in the regulation of cGMP in isolated porcine pulmonary vessels.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Blotting, Western; Carbon Radioisotopes; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Female; Guanylate Cyclase; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Pulmonary Veins; Purinones; Swine | 1998 |
Effects of antisense oligonucleotide to iNOS on hemodynamic and vascular changes induced by LPS.
Topics: Animals; Aorta; Arginine; Citrulline; Cyclic GMP; Enzyme Inhibitors; Hemodynamics; Lipopolysaccharides; Lung; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Norepinephrine; Oligonucleotides, Antisense; Rats; Rats, Wistar; RNA, Messenger | 1998 |
Plasma and muscle amino acid levels in relation to resting energy expenditure and inflammation in stable chronic obstructive pulmonary disease.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Adipose Tissue; Aged; Alanine; Amino Acids; Arginine; Carrier Proteins; Case-Control Studies; Citrulline; Energy Metabolism; Glutamic Acid; Glutamine; Humans; Lipopolysaccharides; Lung Diseases, Obstructive; Membrane Glycoproteins; Middle Aged; Muscle, Skeletal; Muscular Diseases; Ornithine; Proteins; Rest | 1998 |
Reactivity of the flavin semiquinone of nitric oxide synthase in the oxygenation of arginine to NG-hydroxyarginine, the first step of nitric oxide synthesis.
Topics: Arginine; Citrulline; Electron Spin Resonance Spectroscopy; Flavin-Adenine Dinucleotide; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Oxygen | 1998 |
High concentration of L-arginine suppresses nitric oxide synthase activity and produces reactive oxygen species in NB9 human neuroblastoma cells.
Topics: Arginine; Citrulline; DNA Damage; Enzyme Inhibitors; Humans; Kinetics; Neuroblastoma; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Reactive Oxygen Species; RNA, Messenger; Transcription Factor AP-1; Transcriptional Activation; Tumor Cells, Cultured | 1998 |
Post-absorptive plasma citrulline concentration: a marker of intestinal failure in humans.
Topics: Adult; Arginine; Biomarkers; Citrulline; Humans; Intestinal Absorption; Regression Analysis; Short Bowel Syndrome | 1998 |
Renal arginine metabolism in fasted rats with subacute short bowel syndrome.
Topics: Amino Acids; Animals; Arginine; Citrulline; Fasting; Kidney; Male; p-Aminohippuric Acid; Rats; Rats, Wistar; Renal Plasma Flow; Short Bowel Syndrome; Statistics, Nonparametric; Time Factors | 1998 |
Effect of prostaglandin F2 alpha (PGF2 alpha) on oviductal nitric oxide synthase (NOS) activity: possible role of endogenous NO on PGF2 alpha-induced contractions in rat oviduct.
Topics: Animals; Arginine; Calcium; Chelating Agents; Citrulline; Dinoprost; Egtazic Acid; Enzyme Inhibitors; Fallopian Tubes; Female; Guanidines; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar | 1998 |
Effect of citrulline for arginine replacement on the structure and turnover of phosphopeptide substrates of protein phosphatase-1.
Topics: Alkaline Phosphatase; Animals; Arginine; Binding Sites; Canavanine; Citrulline; Enzyme Activation; Hydrolysis; Oligopeptides; Phosphates; Phosphopeptides; Phosphoprotein Phosphatases; Phosphorylases; Phosphorylation; Protein Binding; Protein Phosphatase 1; Rabbits; Substrate Specificity | 1998 |
De novo synthesis of arginine and ornithine from citrulline in human colon carcinoma cells: metabolic fate of L-ornithine.
Topics: Animals; Animals, Newborn; Arginine; Cell Differentiation; Cell Division; Citrulline; Colonic Neoplasms; Enzyme Inhibitors; Humans; Intestinal Mucosa; Intestines; Microscopy, Electron; Nitric Oxide Synthase; Nitroarginine; Ornithine; Swine; Tumor Cells, Cultured | 1998 |
Expression of NO-synthase in cells of foreign-body and BCG-induced granulomata in mice: influence of L-NAME on the evolution of the lesion.
Topics: Analysis of Variance; Animals; Arginine; Citrulline; Epithelioid Cells; Granuloma, Foreign-Body; Macrophages, Peritoneal; Male; Mice; Mycobacterium bovis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Tuberculoma | 1998 |
Nitric oxide synthase activity in fresh cells from ovarian tumour tissue: relationship of enzyme activity with clinical parameters of patients with ovarian cancer.
Topics: Arginine; Ascites; Biopsy; Citrulline; Female; Humans; Nitric Oxide; Nitric Oxide Synthase; Ovarian Neoplasms; Tumor Cells, Cultured | 1998 |
Progesterone enhances prostaglandin E2 production via interaction with nitric oxide in the mouse acrosome reaction.
Topics: Acrosome Reaction; Animals; Arginine; Citrulline; Cyclic GMP; Dinoprostone; Enzyme Inhibitors; Exocytosis; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Progesterone; Spermatozoa | 1998 |
Relationship between mouse uterine contractility, nitric oxide and prostaglandin production in early pregnancy.
Topics: Animals; Arginine; Citrulline; Dinoprost; Enzyme Inhibitors; Female; Mice; Mice, Inbred Strains; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins E; Uterus | 1998 |
Synthesis of boronic acid analogs of L-arginine as alternate substrates or inhibitors of nitric oxide synthase.
Topics: Arginine; Boronic Acids; Citrulline; Enzyme Inhibitors; Models, Chemical; Nitric Oxide Synthase; Recombinant Proteins | 1998 |
Nitric oxide synthesis is increased in periodontal disease.
Topics: Arginine; Case-Control Studies; Citrulline; Epoprostenol; Humans; Nitric Oxide; Nitric Oxide Synthase; Periodontitis | 1998 |
Inability of rat alveolar macrophages to recycle L-citrulline to L-arginine despite induction of argininosuccinate synthetase mRNA and protein, and inhibition of nitric oxide synthesis by exogenous L-citrulline.
Topics: Animals; Arginine; Argininosuccinate Lyase; Blotting, Western; Cells, Cultured; Citrulline; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Lipopolysaccharides; Macrophages, Alveolar; Male; Nitric Oxide; Rats; RNA, Messenger | 1998 |
The epitopes targeted by the rheumatoid arthritis-associated antifilaggrin autoantibodies are posttranslationally generated on various sites of (pro)filaggrin by deimination of arginine residues.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Arthritis, Rheumatoid; Autoantibodies; Citrulline; Epidermis; Epithelium; Epitopes; Filaggrin Proteins; Humans; Hydrolases; Intermediate Filament Proteins; Molecular Sequence Data; Peptide Fragments; Protein Precursors; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Recombinant Proteins | 1999 |
Nitric oxide synthase.
Topics: Animals; Arginine; Brain; Chromatography, Ion Exchange; Citrulline; Humans; Indicators and Reagents; Ion Exchange Resins; Kinetics; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rabbits | 1998 |
cGMP production is coupled to Ca(2+)-dependent nitric oxide generation in rabbit parotid acinar cells.
Topics: Aminoquinolines; Animals; Arginine; Calcimycin; Calcium; Citrulline; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Methacholine Chloride; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Parotid Gland; Rabbits; Receptors, Muscarinic; Thapsigargin; Time Factors | 1998 |
Inhibition of astroglial nitric oxide synthase type 2 expression by idazoxan.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Arginine; Astrocytes; Cell Line; Cell-Free System; Chloramphenicol O-Acetyltransferase; Citrulline; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Idazoxan; Lipopolysaccharides; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Norepinephrine; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; RNA, Messenger; Time Factors; Tumor Cells, Cultured | 1999 |
Synergistic protective effects of selected arginine analogues against sulphur mustard toxicity in neuron culture.
Topics: Animals; Arginine; Carcinogens; Cells, Cultured; Chick Embryo; Citrulline; Drug Synergism; Mustard Gas; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Thiourea | 1999 |
The recycling of L-citrulline to L-arginine in a chicken macrophage cell line.
Topics: Animals; Arginine; Aspartic Acid; Cell Line; Chickens; Citrulline; Culture Media; Macrophages; Nitric Oxide; Nitric Oxide Synthase | 1999 |
Rapid assay for nitric oxide synthase using thin-layer chromatography.
Topics: Animals; Arginine; Carbon Radioisotopes; Chromatography, Thin Layer; Citrulline; Hippocampus; Mice; Nitric Oxide Synthase; Substrate Specificity | 1999 |
Effects of castration and androgen replacement on erectile function in a rabbit model.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Blood Pressure; Blotting, Western; Citrulline; Electric Stimulation; Estradiol; Hemodynamics; Hormone Replacement Therapy; Male; Models, Biological; Muscle, Smooth; Nitric Oxide Synthase; Orchiectomy; Penile Erection; Penis; Rabbits; Receptors, Adrenergic, alpha; Testosterone | 1999 |
Intracellular polyamine levels are involved in NMDA-evoked nitric oxide production in chick retina cells.
Topics: Animals; Arginine; Cells, Cultured; Chick Embryo; Citrulline; Cyclic GMP; Eflornithine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; N-Methylaspartate; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Polyamines; Receptors, N-Methyl-D-Aspartate; Retina; Spermidine | 1999 |
Reduced arginine plasma levels are the drive for arginine production by the kidney in the rat.
Topics: Animals; Arginase; Arginine; Blood Chemical Analysis; Cattle; Citrulline; Digestive System; Endotoxemia; Kidney; Liver; Male; Nitrates; Nitrites; Ornithine; Rats; Rats, Wistar; Regional Blood Flow | 1999 |
Effects of ethanol on intraovarian nitric oxide production in the prepubertal rat.
Topics: Animals; Arginine; Blotting, Western; Citrulline; Estradiol; Ethanol; Female; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Ovary; Rats; Rats, Sprague-Dawley; Sexual Maturation | 1999 |
Dietary glutamine supplementation reduces plasma nitrate levels in rats.
Topics: Animals; Arginine; Citrulline; Dietary Supplements; Glutamine; Kinetics; Male; Nitrates; Rats; Rats, Inbred F344 | 1998 |
Nutrient uptake by viscera drained by the portal vein in neonatal calves during intravenous infusion of glutamine.
Topics: Absorption; Animals; Animals, Newborn; Arginine; Blood Glucose; Cattle; Citrulline; Glutamine; Infusions, Intravenous; Intestines; Male; Oxygen Consumption; Proline; Regeneration; Time Factors; Viscera | 1999 |
Methylene blue inhibits hippocampal nitric oxide synthase activity in vivo.
Topics: Animals; Arginine; Biological Transport; Citrulline; Enzyme Inhibitors; Hippocampus; Male; Methylene Blue; Microdialysis; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Tritium | 1999 |
Nitric oxide production is reduced in patients with chronic renal failure.
Topics: Arginine; Arteriosclerosis; Blood Pressure; Cholesterol; Citrulline; Creatinine; Female; Humans; Hyperlipoproteinemia Type II; Kidney Failure, Chronic; Male; Nitric Oxide; Risk Factors; Smoking; Triglycerides | 1999 |
Lactate inhibits citrulline and arginine synthesis from proline in pig enterocytes.
Topics: Animal Nutritional Physiological Phenomena; Animals; Animals, Suckling; Arginine; Citrulline; Enzyme Inhibitors; Glutamine; Jejunum; Kinetics; Lactic Acid; Mitochondria; Proline; Proline Oxidase; Swine | 1999 |
Nitric oxide production is low in end-stage renal disease patients on peritoneal dialysis.
Topics: Adult; Aged; Arginine; Citrulline; Creatinine; Cyclic GMP; Female; Humans; Hypertension, Renal; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Peritoneal Dialysis | 1999 |
Synthesis and evaluation of new sulfur-containing L-arginine-derived inhibitors of nitric oxide synthase.
Topics: Arginine; Citrulline; Enzyme Inhibitors; Heme; Isoenzymes; NADPH Oxidases; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Structure-Activity Relationship | 1999 |
Interleukin 1beta increases arginine accumulation and activates the citrulline-NO cycle in rat pancreatic beta cells.
Topics: Amino Acid Transport Systems; Amino Acids; Animals; Arginine; Biological Transport; Carrier Proteins; Cells, Cultured; Citrulline; Interleukin-1; Islets of Langerhans; Lysine; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 1999 |
Metabolic capacity for L-citrulline synthesis from ammonia in rat isolated colonocytes.
Topics: Ammonia; Ammonium Chloride; Animals; Arginase; Arginine; Argininosuccinate Synthase; Cell Survival; Cells, Cultured; Citrulline; Colon; Ketoglutaric Acids; Male; Ornithine Carbamoyltransferase; Oxidation-Reduction; Rats; Rats, Inbred F344; Urea | 1999 |
Arginine dihydrolase pathway in Lactobacillus plantarum from orange.
Topics: Ammonia; Arginine; Beverages; Citrulline; Citrus; Colorimetry; Glucose; Hydrogen-Ion Concentration; Hydrolases; Lactobacillus; Ornithine; Spectrophotometry; Urea | 1999 |
Autoinhibition of neuronal nitric oxide synthase: distinct effects of reactive nitrogen and oxygen species on enzyme activity.
Topics: Animals; Arginine; Cerebellum; Citrulline; Feedback; Free Radical Scavengers; Glutathione; Hydrogen Peroxide; Inhibitory Concentration 50; Kinetics; Methemoglobin; Methionine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrogen; Reactive Oxygen Species; Superoxide Dismutase; Swine | 1999 |
Stimulation of NO synthase activity in the immune-competent lepidopteran Estigmene acraea hemocyte line.
Topics: Animals; Arginine; Cell Line; Citrulline; Enzyme Activation; Enzyme Inhibitors; Hemocytes; Immunocompetence; Kinetics; Lepidoptera; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Superoxide Dismutase | 1999 |
Activation of nitric oxide synthase by beta 2-adrenoceptors in human umbilical vein endothelium in vitro.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Arginine; Calcium; Cells, Cultured; Citrulline; Cyclic AMP; Cytoplasm; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Receptors, Adrenergic, beta-2; Umbilical Veins | 1999 |
Effect of L-arginine load on platelet aggregation: a comparison between normotensive and preeclamptic pregnant women.
Topics: Adenosine Diphosphate; Adult; Arginine; Citrulline; Collagen; Female; Humans; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Pre-Eclampsia; Pregnancy | 1999 |
Maternal cigarette smoking increases F2-isoprostanes and reduces prostacyclin and nitric oxide in umbilical vessels.
Topics: Adult; Arginine; Citrulline; Cysteine; Dinoprost; Dinoprostone; Epoprostenol; F2-Isoprostanes; Female; Humans; Nitric Oxide; Pregnancy; Smoking; Umbilical Arteries; Umbilical Cord; Umbilical Veins; Vasoconstriction | 1999 |
Characterization and regional distribution of nitric oxide synthase in the human brain during normal ageing.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Brain; Cadaver; Child; Child, Preschool; Citrulline; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Reference Values; Tissue Distribution | 1999 |
L-arginine uptake, the citrulline-NO cycle and arginase II in the rat brain: an in situ hybridization study.
Topics: Amino Acid Transport Systems, Basic; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Brain; Carrier Proteins; Citrulline; In Situ Hybridization; Male; Membrane Proteins; Nerve Tissue Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase; Organ Specificity; Rats; Rats, Sprague-Dawley | 1999 |
No detectable NO synthesis from L-arginine or N(G)-hydroxy-L-arginine in fMLP-stimulated human blood neutrophils despite production of nitrite, nitrate, and citrulline from N(G)-hydroxy-L-arginine.
Topics: Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Nitroarginine | 1999 |
Cationic proteins inhibit L-arginine uptake in rat alveolar macrophages and tracheal epithelial cells. Implications for nitric oxide synthesis.
Topics: Animals; Arginase; Arginine; Blood Proteins; Citrulline; Dose-Response Relationship, Drug; Eosinophil Granule Proteins; Epithelial Cells; Female; Fibrinolytic Agents; Gene Expression; Heparin; Lipopolysaccharides; Lung; Lysine; Macrophages, Alveolar; Male; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Ribonucleases; Time Factors; Trachea | 1999 |
Highly deiminated isoform of myelin basic protein from multiple sclerosis brain causes fragmentation of lipid vesicles.
Topics: Animals; Arginine; Cattle; Citrulline; Electrochemistry; Humans; Imines; Light; Liposomes; Multiple Sclerosis; Myelin Basic Protein; Protein Isoforms; Scattering, Radiation | 1999 |
Expression of inducible nitric oxide synthase and enzymes of arginine metabolism in Fusarium kyushuense-exposed mouse lung.
Topics: Amino Acid Transport Systems, Basic; Animals; Arginase; Arginine; Argininosuccinate Synthase; Carrier Proteins; Citrulline; Enzyme Induction; Female; Fusarium; Isoenzymes; Kinetics; Lung Diseases, Fungal; Membrane Proteins; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; RNA, Messenger | 1999 |
Systemic administration of cocaine, given alone or in combination with sensory stimuli, differentially affects L-arginine-nitric oxide metabolism in discrete regions of the brain of rat.
Topics: Acoustic Stimulation; Animals; Arginine; Brain; Brain Mapping; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Citrulline; Cocaine; Corpus Striatum; Drug Administration Schedule; Frontal Lobe; Hippocampus; Injections, Intraperitoneal; Male; Nitric Oxide; Rats; Rats, Wistar | 1999 |
Lead acetate exposure inhibits nitric oxide synthase activity in capillary and synaptosomal fractions of mouse brain.
Topics: Animals; Arginine; Brain; Capillaries; Citrulline; Dose-Response Relationship, Drug; Lead; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Organometallic Compounds; Random Allocation; Synaptosomes | 1999 |
Tetrahydrobiopterin-dependent inhibition of superoxide generation from neuronal nitric oxide synthase.
Topics: Animals; Arginine; Biopterins; Cattle; Citrulline; Electron Spin Resonance Spectroscopy; Models, Chemical; NADP; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxygen; Superoxides | 1999 |
Reduced nitric oxide production by L-arginine deficiency in lysinuric protein intolerance exacerbates intravascular coagulation.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Antithrombin III; Arginine; Blood Coagulation Disorders; Citrulline; Cyclic GMP; Humans; Lysine; Male; Nitric Oxide; Nitroglycerin; Ornithine; Peptide Hydrolases; Platelet Aggregation; Thrombosis | 1999 |
Localization and activity of nitric oxide synthases in the gastrointestinal tract of Trypanosoma cruzi-infected mice.
Topics: Animals; Arginine; Calcium; Chagas Disease; Citrulline; Colon; Digestive System; Enzyme Inhibitors; Epithelial Cells; Esophagus; Female; Ileum; Intestinal Mucosa; Isoenzymes; Male; Mice; Mice, Inbred C3H; Muscle, Smooth; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Stomach; Trypanosoma cruzi | 1999 |
Peroxynitrite anion stimulates arginine release from cultured rat astrocytes.
Topics: Animals; Animals, Newborn; Arginine; Astrocytes; Cells, Cultured; Citrulline; Glutamic Acid; Hydrogen Peroxide; Kinetics; Lysine; Nitrates; Nitric Oxide Donors; Oxidants; Rats; Rats, Wistar; Serine | 1999 |
Changes in amino acid concentrations over time and space around an impact injury and their diffusion through the rat spinal cord.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Citrulline; Glutamic Acid; Glycine; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine; Time Factors | 1999 |
L-arginine increases UVA cytotoxicity in irradiated human keratinocyte cell line: potential role of nitric oxide.
Topics: Antioxidants; Arginine; Catalase; Cell Line; Cell Survival; Citrulline; DNA Damage; Humans; Keratinocytes; Metalloproteins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Penicillamine; Poly(ADP-ribose) Polymerases; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Thiourea; Ultraviolet Rays | 1999 |
7-Nitroindazole, a selective inhibitor of nNOS, increases hippocampal extracellular glutamate concentration in status epilepticus induced by kainic acid in rats.
Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Citrulline; Electroencephalography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Extracellular Space; Glutamic Acid; Hippocampus; Indazoles; Kainic Acid; Male; Microdialysis; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Status Epilepticus; Synaptic Transmission | 1999 |
Aberrations of ammonia metabolism in ornithine carbamoyltransferase-deficient spf-ash mice and their prevention by treatment with urea cycle intermediate amino acids and an ornithine aminotransferase inactivator.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Ammonium Chloride; Animals; Arginine; Citrulline; Enzyme Inhibitors; Injections, Intraperitoneal; Liver; Male; Mice; Mice, Transgenic; Ornithine; Ornithine Carbamoyltransferase Deficiency Disease; Perfusion; Urea | 1999 |
Glutamine is essential for nitric oxide synthesis by murine macrophages.
Topics: Animals; Arginine; Cell Line; Cell Survival; Citrulline; Extracellular Space; Glutamine; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide | 1999 |
Reaction of neuronal nitric oxide synthase with the nitric oxide spin-trapping agent, iron complexed with N-dithiocarboxysarcosine.
Topics: Animals; Arginine; Citrulline; Electron Spin Resonance Spectroscopy; Electron Transport; Enzyme Inhibitors; Ferric Compounds; Heme; In Vitro Techniques; Iron; Mice; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxygen Consumption; Spin Labels; Swine; Thiocarbamates | 1999 |
Expression of citrulline-nitric oxide cycle in lipopolysaccharide and cytokine-stimulated rat astroglioma C6 cells.
Topics: Animals; Arginine; Astrocytoma; Citrulline; Cytokines; Enzyme Induction; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Interferon-gamma; Kinetics; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Kinetic studies on the successive reaction of neuronal nitric oxide synthase from L-arginine to nitric oxide and L-citrulline.
Topics: Animals; Arginine; Citrulline; Enzyme Activation; Kinetics; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Spectrophotometry; Temperature | 1999 |
Plasma concentrations and renal clearance of orotic acid in argininosuccinic acid synthetase deficiency.
Topics: Amino Acids; Arginine; Child; Chromatography, Gas; Citrulline; Citrullinemia; Creatinine; Glutamine; Humans; Male; Ornithine; Orotic Acid; Quaternary Ammonium Compounds; Time Factors | 1999 |
Segmental and laminar distributions of nicotinamide adenine dinucleotide phosphate-diaphorase-expressing and neuronal nitric oxide synthase-immunoreactive neurons versus radioassay detection of catalytic nitric oxide synthase activity in the rabbit spinal
Topics: Animals; Arginine; Catalysis; Citrulline; Female; Male; NADPH Dehydrogenase; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rabbits; Radioimmunoassay; Spinal Cord; Tritium | 1999 |
L-Arginine-nitric oxide pathway-related metabolites in the aqueous humor of diabetic patients.
Topics: Aged; Aged, 80 and over; Aqueous Humor; Arginine; Chromatography, High Pressure Liquid; Citrulline; Diabetic Retinopathy; Humans; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Up-Regulation | 2000 |
Increase in renal medullary nitric oxide synthase activity protects from norepinephrine-induced hypertension.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Arginine; Blood Pressure; Chromatography, High Pressure Liquid; Citrulline; Consciousness; Enzyme Activation; Hypertension; Infusions, Intravenous; Kidney Cortex; Kidney Medulla; Male; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sympathomimetics; Yohimbine | 2000 |
Ethyl carbamate precursor citrulline formation from arginine degradation by malolactic wine lactic acid bacteria.
Topics: Arginine; Carcinogens; Citrulline; Fermentation; Hydrogen-Ion Concentration; Lactates; Lactobacillaceae; Malates; Urethane; Wine | 2000 |
Effects of selected arginine analogues on sulphur mustard toxicity in human and hairless guinea pig skin keratinocytes.
Topics: Administration, Topical; Animals; Arginine; Cells, Cultured; Citrulline; Dermatologic Agents; Enzyme Inhibitors; Guinea Pigs; Humans; Keratinocytes; Mustard Gas; NG-Nitroarginine Methyl Ester; Nitroarginine; Organophosphorus Compounds; Skin; Thiourea | 2000 |
Nitric oxide synthesis is increased in periodontitis.
Topics: Adult; Arginine; Case-Control Studies; Citrulline; Epoprostenol; Female; Gingiva; Humans; Male; Middle Aged; Nitric Oxide; Periodontitis; Prostaglandin-Endoperoxide Synthases | 1999 |
Cryoelectron microscopy of protein-lipid complexes of human myelin basic protein charge isomers differing in degree of citrullination.
Topics: Adult; Arginine; Autoimmune Diseases; Citrulline; Cryoelectron Microscopy; G(M1) Ganglioside; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Macromolecular Substances; Microscopy, Electron, Scanning; Multiple Sclerosis; Myelin Basic Protein; Phosphatidylserines; Protein Isoforms; Protein Processing, Post-Translational | 2000 |
P(1),P(4)-Diadenosine 5'-tetraphosphate modulates l-arginine and l-citrulline uptake by bovine aortic endothelial cells.
Topics: Animals; Aorta; Arginine; Binding Sites; Binding, Competitive; Biological Transport; Cattle; Cells, Cultured; Citrulline; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Endothelium, Vascular; Receptors, Cell Surface; Receptors, Purinergic P2; Substrate Specificity; Suramin | 2000 |
Cellular and enzymatic studies of N(omega)-propyl-l-arginine and S-ethyl-N-[4-(trifluoromethyl)phenyl]isothiourea as reversible, slowly dissociating inhibitors selective for the neuronal nitric oxide synthase isoform.
Topics: Animals; Arginine; Calcium; Calmodulin; Cell Line; Citrulline; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoenzymes; Macrophage Activation; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Pituitary Gland; Rats; Substrate Specificity; Thiourea | 2000 |
Formation and reactions of the heme-dioxygen intermediate in the first and second steps of nitric oxide synthesis as studied by stopped-flow spectroscopy under single-turnover conditions.
Topics: Animals; Arginine; Catalysis; Citrulline; Ferrous Compounds; Heme; Kinetics; Models, Chemical; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Oxygen; Rats; Spectrophotometry | 2000 |
Arginine, citrulline and ornithine metabolism by lactic acid bacteria from wine.
Topics: Arginine; Citrulline; Colorimetry; Glucose; Hydrogen-Ion Concentration; Lactobacillaceae; Lactobacillus; Ornithine; Urease; Wine | 1999 |
Nitric oxide-induced autoinhibition of neuronal nitric oxide synthase in the presence of the autoxidation-resistant pteridine 5-methyltetrahydrobiopterin.
Topics: Animals; Arginine; Biopterins; Catalase; Catalysis; Cattle; Citrulline; Dimerization; Free Radical Scavengers; Guanylate Cyclase; Heme; Hydrogen Peroxide; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidants; Pteridines; Rats; Superoxide Dismutase; Superoxides | 2000 |
Characterization of an isogenic mutant of Streptococcus pyogenes Manfredo lacking the ability to make streptococcal acid glycoprotein.
Topics: Arginine; Bacterial Proteins; Cell Division; Citrulline; Epithelial Cells; Glycoproteins; Humans; Hydrogen-Ion Concentration; Leukocytes, Mononuclear; Mitogens; Mutagenesis; Phytohemagglutinins; Streptococcus pyogenes | 2000 |
Amino acid release into the knee joint: key role in nociception and inflammation.
Topics: Amino Acids; Anesthetics, Local; Animals; Arginine; Arthritis; Carrageenan; Chromatography, High Pressure Liquid; Citrulline; Glutamic Acid; Hindlimb; Injections, Intra-Articular; Joints; Kaolin; Lidocaine; Male; Pain; Rats; Rats, Sprague-Dawley; Synovial Fluid | 2000 |
Arginine, citrulline, and nitric oxide metabolism in end-stage renal disease patients.
Topics: Adult; Aged; Arginine; Citrulline; Female; Homeostasis; Humans; Infusions, Intravenous; Kidney Failure, Chronic; Kinetics; Leucine; Male; Middle Aged; Nitric Oxide; Renal Dialysis | 2000 |
Catalytic nitric oxide synthase activity in the white and gray matter regions of the spinal cord of rabbits.
Topics: Animals; Arginine; Catalysis; Cervical Vertebrae; Citrulline; Lumbosacral Region; Male; Nitric Oxide Synthase; Rabbits; Spinal Cord; Thoracic Vertebrae; Tissue Distribution; Tritium | 2000 |
Decreased plasma concentrations of L-hydroxy-arginine as a marker of reduced NO formation in patients with combined cardiovascular risk factors.
Topics: Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Citrulline; Female; Humans; Hyperglycemia; Hyperlipidemias; Hypertension; Male; Mass Spectrometry; Middle Aged; Nitric Oxide; Obesity; Risk Factors; Syndrome | 2000 |
Deimination of myelin basic protein. 1. Effect of deimination of arginyl residues of myelin basic protein on its structure and susceptibility to digestion by cathepsin D.
Topics: Animals; Arginine; Cathepsins; Cattle; Chromatography, High Pressure Liquid; Citrulline; Demyelinating Autoimmune Diseases, CNS; Hydrolases; Kinetics; Mass Spectrometry; Models, Molecular; Myelin Basic Protein; Peptide Fragments; Protein Conformation; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases | 2000 |
Deimination of myelin basic protein. 2. Effect of methylation of MBP on its deimination by peptidylarginine deiminase.
Topics: Animals; Arginine; Brain; Cathepsin D; Cattle; Citrulline; Humans; Hydrolases; Kinetics; Mass Spectrometry; Methylation; Multiple Sclerosis; Myelin Basic Protein; Peptide Fragments; Protein Processing, Post-Translational; Protein Structure, Secondary; Protein Structure, Tertiary; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases | 2000 |
L-glutamate, L-arginine and L-citrulline levels in cerebrospinal fluid of Parkinson's disease, multiple system atrophy, and Alzheimer's disease patients.
Topics: Aged; Alzheimer Disease; Arginine; Citrulline; Glutamic Acid; Humans; Middle Aged; Multiple System Atrophy; Neurons; Nitric Oxide; Nitric Oxide Synthase; Parkinson Disease | 2000 |
Characterization of L-arginine transporters in rat renal inner medullary collecting duct.
Topics: Amino Acid Transport Systems; Animals; Arginine; beta-Alanine; Biological Transport; Carrier Proteins; Cations; Citrulline; Enzyme Inhibitors; Gene Expression; Homeostasis; Kidney Medulla; Kidney Tubules, Collecting; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substrate Specificity; Tritium; Water-Electrolyte Balance | 2000 |
Normal circulating adult human red blood cells contain inactive NOS proteins.
Topics: Arginase; Arginine; Chromatography, Thin Layer; Citrulline; Enzyme Inhibitors; Erythrocytes; Humans; Hydrolysis; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Valine | 2000 |
Citrulline does not relax isolated rat and rabbit vessels.
Topics: Animals; Aorta, Thoracic; Arginine; Carotid Arteries; Citrulline; Dose-Response Relationship, Drug; Female; Femoral Artery; In Vitro Techniques; Male; Molsidomine; Nitric Oxide Donors; Norepinephrine; Rabbits; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2000 |
Dietary arginine requirement of juvenile red drum (Sciaenops ocellatus) based on weight gain and feed efficiency.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Aquaculture; Arginine; Aspartic Acid; Citrulline; Energy Intake; Fishes; Glutamic Acid; Glycine; Nutritional Requirements; Ornithine; Weight Gain | 2000 |
A study to assess inducible nitric oxide synthase expression in oral lichen planus.
Topics: Adult; Aged; Aged, 80 and over; Antibodies; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Arginine; Citrulline; Coloring Agents; Down-Regulation; Female; Gene Expression Regulation, Enzymologic; Humans; Lichen Planus, Oral; Macrophages; Male; Middle Aged; Mouth Mucosa; Nitric Oxide Synthase | 2000 |
Indicators of L-arginine metabolism and cardiovascular risk factors--a cross-sectional study in healthy middle-aged men.
Topics: Adult; Arginine; Blood Pressure; Cardiovascular Diseases; Cholesterol, LDL; Citrulline; Creatinine; Cross-Sectional Studies; Humans; Male; Middle Aged; Orotic Acid; Risk Factors | 2000 |
Characterisation of nitric oxide synthase activity in the tropical sea anemone Aiptasia pallida.
Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Epithelial Cells; NADP; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Sea Anemones; Staining and Labeling; Valine | 2000 |
Measurement of NOS activity by conversion of radiolabeled arginine to citrulline using ion-exchange separation.
Topics: Animals; Arginine; Carbon Radioisotopes; Cell Fractionation; Chromatography, Ion Exchange; Citrulline; Enzyme Inhibitors; Nitric Oxide Synthase; omega-N-Methylarginine; Radioisotope Dilution Technique; Tritium | 1998 |
Radiochemical measurement of NOS activity by conversion of [14C]L-arginine to citrulline using HPLC separation.
Topics: Animals; Arginine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Citrulline; Indicators and Reagents; Insulinoma; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pancreatic Neoplasms; Radioisotope Dilution Technique; Rats; Tumor Cells, Cultured | 1998 |
Changes of endothelial nitric oxide synthase level and activity during endothelial cell proliferation.
Topics: Animals; Arginine; Cattle; Cell Division; Cells, Cultured; Citrulline; Endothelium, Vascular; Kinetics; Luminescent Measurements; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Superoxide Dismutase; Superoxides | 2000 |
Acute blockade of nitric oxide synthesis induces disorganization and amplifies lesion-induced plasticity in the rat retinotectal projection.
Topics: Animals; Arginine; Axons; Citrulline; Enzyme Inhibitors; NADPH Dehydrogenase; Neuronal Plasticity; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Inbred Strains; Retina; Superior Colliculi; Visual Pathways | 2000 |
Arginine conversion to nitroxide by tetrahydrobiopterin-free neuronal nitric-oxide synthase. Implications for mechanism.
Topics: Arginine; Biopterins; Catalysis; Citrulline; Heme; Hydrogen Peroxide; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidation-Reduction | 2000 |
Increased L-citrulline/L-arginine plasma ratio in severe preeclampsia.
Topics: Adult; Arginine; Birth Weight; Chromatography, High Pressure Liquid; Citrulline; Female; Gestational Age; Humans; Infant, Newborn; Nitric Oxide; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Reference Values | 2000 |
Decrease of neuronal nitric oxide synthase in the cerebellum of aged rats.
Topics: Aging; Animals; Arginine; Blotting, Northern; Blotting, Western; Cerebellum; Citrulline; Densitometry; Electrophoresis, Polyacrylamide Gel; Glyceraldehyde-3-Phosphate Dehydrogenases; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; RNA, Messenger | 2000 |
Neurochemical changes after morphine, dizocilpine or riluzole in the ventral posterolateral thalamic nuclei of rats with hyperalgesia.
Topics: Analysis of Variance; Animals; Arginine; Aspartic Acid; Carrageenan; Citrulline; Dialysis Solutions; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamic Acid; Hindlimb; Hyperalgesia; Male; Microdialysis; Morphine; Neuroprotective Agents; Rats; Rats, Wistar; Riluzole; Thalamic Nuclei | 2000 |
Modulation of the nitric oxide pathway by copper in glial cells.
Topics: Animals; Arginine; Citrulline; Copper; Cyclic GMP; Gene Expression Regulation, Enzymologic; Interferon-gamma; Isoenzymes; Lipopolysaccharides; Neuroglia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Rats; RNA, Messenger; Tumor Cells, Cultured | 2000 |
Postnatal changes of plasma amino acids in suckling pigs.
Topics: Amino Acids; Animals; Animals, Newborn; Arginine; Body Weight; Citrulline; Female; Male; Ornithine; Swine | 2000 |
Endotoxin augments cerebral hyperemic response to halothane by inducing nitric oxide synthase and cyclooxygenase.
Topics: Anesthetics, Inhalation; Animals; Arginine; Cerebrovascular Circulation; Citrulline; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Endotoxins; Enzyme Inhibitors; Escherichia coli; Guanidines; Halothane; Hydrazines; Hyperemia; Isoenzymes; Laser-Doppler Flowmetry; Lipopolysaccharides; Male; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrobenzenes; Nitrogen Oxides; Peroxidases; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Sulfonamides | 2000 |
Arginine to citrulline replacement in substrates of phosphorylase kinase.
Topics: Amino Acid Sequence; Arginine; Citrulline; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Phosphorylase Kinase; Phosphorylation; Protein Conformation; Substrate Specificity | 2000 |
L-arginine attenuates trauma-hemorrhage-induced liver injury.
Topics: Animals; Arginine; Citrulline; Endothelium, Vascular; Glutathione Transferase; Hemodynamics; Hemorrhage; Immunity, Cellular; Liver; Male; Neutrophil Infiltration; Nitric Oxide; Ornithine; Prospective Studies; Rats; Rats, Sprague-Dawley; Resuscitation | 2000 |
A highly sensitive high-performance liquid chromatography-- fluorometric method for the assay of peptidylarginine deiminase activity.
Topics: Animals; Arginine; Brain; Chromatography, High Pressure Liquid; Citrulline; Dansyl Compounds; Fluorometry; Glycine; HL-60 Cells; Humans; Hydrogen-Ion Concentration; Hydrolases; Male; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Rats; Rats, Wistar; Sensitivity and Specificity; Substrate Specificity; Urea | 2000 |
Kinetics of the arginine metabolism of malolactic wine lactic acid bacteria Lactobacillus buchneri CUC-3 and Oenococcus oeni Lo111.
Topics: Arginine; Citrulline; Fermentation; Fructose; Glucose; Gram-Positive Cocci; Kinetics; Leuconostoc; Ribose; Wine | 2000 |
The inhibitory potency and selectivity of arginine substrate site nitric-oxide synthase inhibitors is solely determined by their affinity toward the different isoenzymes.
Topics: Arginine; Citrulline; Enzyme Inhibitors; Humans; Isoenzymes; Nitric Oxide Synthase; Picolines; Radioligand Assay; Substrate Specificity; Tritium | 2000 |
Modulation of nitric-oxide synthase by nicotine.
Topics: Animals; Aorta, Thoracic; Arginine; Biopterins; Citrulline; Dogs; Endothelium, Vascular; Flavin-Adenine Dinucleotide; Male; NADP; Nicotine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Recombinant Proteins | 2000 |
Electrochemical detection of nitroso-arginine as an intermediate between N-hydroxy-arginine and citrulline. An in vitro versus in vivo study using microcarbon electrodes in neuronal nitric oxide synthase and mice brain.
Topics: Animals; Arginine; Brain; Brain Chemistry; Citrulline; Electrochemistry; Mice; Microelectrodes; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Nitroso Compounds; Oxidation-Reduction; Surface Properties | 2000 |
Coinduction of inducible nitric oxide synthase and arginine recycling enzymes in cytokine-stimulated PC12 cells and high output production of nitric oxide.
Topics: Animals; Antineoplastic Agents; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Bucladesine; Citrulline; Dexamethasone; Gene Expression Regulation, Enzymologic; Glucocorticoids; Interferon-gamma; Lipopolysaccharides; Nerve Growth Factor; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; PC12 Cells; Rats; RNA, Messenger; Tumor Necrosis Factor-alpha | 2000 |
p(1),p(4)-diadenosine 5'-tetraphosphate induces the uptake of arginine and citrulline by a pore on the plasma membrane of bovine aortic endothelial cells.
Topics: Animals; Aorta; Arginine; Argininosuccinic Acid; Autoradiography; Cattle; Cell Membrane Structures; Cells, Cultured; Citrulline; Cycloheximide; Dinucleoside Phosphates; Endothelium, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Protein Synthesis Inhibitors; Suramin; Temperature; Tritium | 2000 |
Hyperammonemia with reduced ornithine, citrulline, arginine and proline: a new inborn error caused by a mutation in the gene encoding delta(1)-pyrroline-5-carboxylate synthase.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Animals; Arginine; Catalytic Domain; Child; CHO Cells; Citrulline; Cricetinae; DNA Mutational Analysis; Female; Fibroblasts; France; Humans; Hyperammonemia; Male; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Pedigree; Phenotype; Proline; RNA, Messenger; Transfection | 2000 |
2-thiouracil is a selective inhibitor of neuronal nitric oxide synthase antagonising tetrahydrobiopterin-dependent enzyme activation and dimerisation.
Topics: Animals; Antithyroid Agents; Arginine; Binding, Competitive; Biopterins; Cerebellum; Citrulline; Cytochrome c Group; Dimerization; Enzyme Activation; Enzyme Inhibitors; Hydrogen Peroxide; Kinetics; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Thiouracil | 2000 |
Regulation of the successive reaction catalyzed by rat neuronal nitric oxide synthase.
Topics: Animals; Arginine; Calmodulin; Citrulline; Electron Transport; Gene Expression Regulation, Enzymologic; NADP; Nerve Tissue Proteins; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Recombinant Proteins | 2000 |
C60-Fullerene monomalonate adducts selectively inactivate neuronal nitric oxide synthase by uncoupling the formation of reactive oxygen intermediates from nitric oxide production.
Topics: Animals; Arginine; Carbon; Catalysis; Cattle; Cell Line; Citrulline; Fullerenes; Hydrogen Peroxide; Isoenzymes; Kinetics; Malonates; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Reactive Oxygen Species | 2001 |
Long-term management of patients with urea cycle disorders.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Carbamoyl-Phosphate Synthase (Ammonia); Citrulline; Dietary Proteins; Humans; Hyperammonemia; Ornithine Carbamoyltransferase Deficiency Disease; Phenylbutyrates; Urea | 2001 |
Antineutrophil cytoplasm antibody-induced neutrophil nitric oxide production is nitric oxide synthase independent.
Topics: Antibodies, Antineutrophil Cytoplasmic; Arginine; Cells, Cultured; Citrulline; Endothelium, Vascular; Humans; Luminescent Measurements; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Polymerase Chain Reaction; RNA, Messenger | 2001 |
Nitric oxide generation by hemocytes of the mussel Mytilus galloprovincialis.
Topics: Animals; Arginine; Bivalvia; Citrulline; Enzyme Inhibitors; Hemocytes; Latex; Luminescent Measurements; Microspheres; NADPH Oxidases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Phagocytosis; Superoxide Dismutase; Superoxides | 2001 |
Arginine catabolism by Thermanaerovibrio acidaminovorans.
Topics: Acetates; Adenosine Triphosphate; Arginine; Citrulline; Energy Metabolism; Gram-Negative Anaerobic Bacteria; Hydrogen; Hydrolases; Methanobacterium; Ornithine; Propionates; Quaternary Ammonium Compounds; Temperature; Thermodynamics | 2001 |
L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat.
Topics: Adrenocorticotropic Hormone; Amino Acids; Animals; Arginine; Citrulline; Cyclic GMP; Drug Evaluation; Hypertension; Male; Nitrates; Nitric Oxide; Nitrites; Random Allocation; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2000 |
Metabolic flux measurements across portal drained viscera, liver, kidney and hindquarter in mice.
Topics: Amino Acids; Animals; Arginine; Blood Flow Velocity; Catheterization; Citrulline; Female; Glutamine; Hindlimb; Kidney; Liver; Male; Mice; Models, Animal; Portal System; Regional Blood Flow; Specific Pathogen-Free Organisms; Viscera | 2001 |
Insulin restores neuronal nitric oxide synthase expression in streptozotocin-induced diabetic rats.
Topics: Animals; Arginine; Blood Glucose; Blotting, Northern; Blotting, Western; Citrulline; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Insulin; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar | 2000 |
Neural network partitioning by NO and cGMP.
Topics: Animals; Arginine; Brachyura; Citrulline; Cyclic GMP; Digestive System; Enzyme Inhibitors; Fluorescent Dyes; Ganglia, Invertebrate; Guanylate Cyclase; Immunohistochemistry; In Vitro Techniques; Isoquinolines; Male; Nerve Net; Neurons; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Donors; Periodicity; Signal Transduction | 2001 |
Nitric oxide synthases in pregnant rat uterus.
Topics: Animals; Arginine; Blotting, Western; Carbon Radioisotopes; Citrulline; Diestrus; Female; Gestational Age; Guanidines; Labor, Obstetric; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pregnancy; Rats; Rats, Wistar; Uterus | 2001 |
Effect of arginine on cyclosporine-induced systemic hypertension after cardiac transplantation in the young.
Topics: Adolescent; Adult; Arginine; Blood Pressure; Case-Control Studies; Chromatography, High Pressure Liquid; Citrulline; Cyclosporine; Echocardiography; Female; Heart Transplantation; Humans; Hypertension; Immunosuppressive Agents; Infusions, Intravenous; Male; Ventricular Function, Left | 2001 |
Hypochlorite-modified low density lipoprotein inhibits nitric oxide synthesis in endothelial cells via an intracellular dislocalization of endothelial nitric-oxide synthase.
Topics: Antioxidants; Arginine; Biopterins; Blotting, Western; Cell Membrane; Cells, Cultured; Centrifugation, Density Gradient; Citrulline; Cyclic GMP; Cyclodextrins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Golgi Apparatus; Humans; Hypochlorous Acid; Immunoblotting; Immunohistochemistry; Ionomycin; Ionophores; Lipoproteins, LDL; Microscopy, Fluorescence; Myristic Acids; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Palmitic Acids; Precipitin Tests; RNA, Messenger; Subcellular Fractions; Sucrose; Time Factors; Umbilical Veins | 2001 |
Indomethacin prevents the induction of inducible nitric oxide synthase in murine peritoneal macrophages and decreases their nitric oxide production.
Topics: Animals; Arginase; Arginine; Blotting, Western; Citrulline; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Induction; Indomethacin; Macrophages, Peritoneal; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Uridine | 2001 |
Caveolar localization of arginine regeneration enzymes, argininosuccinate synthase, and lyase, with endothelial nitric oxide synthase.
Topics: Animals; Aorta; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Blotting, Western; Bradykinin; Cattle; Caveolae; Chromatography, High Pressure Liquid; Citrulline; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III | 2001 |
Time course of inducible nitric oxide synthase activity following endotoxin administration in dogs.
Topics: Animals; Arginine; Chromatography, Thin Layer; Citrulline; Dogs; Endotoxins; Enzyme Induction; Intestines; Kidney; Liver; Lung; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Shock, Septic; Substrate Specificity; Time Factors | 2001 |
Retinoic acid attenuates inducible nitric oxide synthase (NOS2) activation in cultured rat cardiac myocytes and microvascular endothelial cells.
Topics: Animals; Arginine; Blotting, Northern; Blotting, Western; Cells, Cultured; Citrulline; Dactinomycin; Endothelium, Vascular; Enzyme Activation; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Macrophages, Alveolar; Male; Microcirculation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Time Factors; Tretinoin | 2001 |
Nitric oxide synthase in porcine heart mitochondria: evidence for low physiological activity.
Topics: Animals; Arginine; Cell Respiration; Citrulline; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Mitochondria, Heart; Mitochondria, Liver; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidative Phosphorylation; Oxygen Consumption; Swine | 2001 |
Convenient method for the determination of arginine and its related compounds in rumen fluid by reversed-phase high-performance liquid chromatography.
Topics: Amino Acids, Neutral; Animals; Arginine; Body Fluids; Buffers; Chromatography, High Pressure Liquid; Citrulline; Gastrointestinal Contents; Goats; Hydrogen-Ion Concentration; Ornithine; Proline; Reproducibility of Results; Rumen; Time Factors | 2001 |
Neonatal pulmonary hypertension--urea-cycle intermediates, nitric oxide production, and carbamoyl-phosphate synthetase function.
Topics: Arginine; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Case-Control Studies; Citrulline; Female; Genetics, Population; Genotype; Humans; Infant, Newborn; Male; Nitric Oxide; Persistent Fetal Circulation Syndrome; Polymorphism, Genetic; Urea | 2001 |
Extremely short small bowel induces focal tubulointerstitial fibrosis.
Topics: Animals; Arginine; Citrulline; Disease Models, Animal; Fibrosis; Immunohistochemistry; Kidney; Male; Orotic Acid; Rats; Rats, Sprague-Dawley; Short Bowel Syndrome | 2001 |
Structural requirements for conserved arginine of parathyroid hormone.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Cell Line; Circular Dichroism; Citrulline; Conserved Sequence; Enzyme Activation; Humans; Molecular Sequence Data; Norleucine; Ornithine; Parathyroid Hormone; Peptide Fragments; Protein Structure, Secondary; Rats; Structure-Activity Relationship | 2001 |
Detection of neonatal argininosuccinate lyase deficiency by serum tandem mass spectrometry.
Topics: Amino Acid Sequence; Amino Acids; Ammonia; Arginine; Argininosuccinate Lyase; Argininosuccinic Acid; Argininosuccinic Aciduria; Base Sequence; Citrulline; Coma; Frameshift Mutation; Humans; Hyperammonemia; Infant, Newborn; Mass Spectrometry; Molecular Sequence Data; Neonatal Screening; Ornithine | 2001 |
Effects of ENA713 and CHF2819, two anti-Alzheimer's disease drugs, on rat amino acid levels.
Topics: Alzheimer Disease; Animals; Arginine; Aspartic Acid; Carbamates; Cholinesterase Inhibitors; Citrulline; Cyclic N-Oxides; Dose-Response Relationship, Drug; Excitatory Amino Acids; Extracellular Space; Glutamic Acid; Hippocampus; Male; Microdialysis; Neurons; Phenylcarbamates; Rats; Rats, Wistar; Rivastigmine; Synaptic Transmission; Taurine | 2001 |
Response of nitric oxide pathway to L-arginine infusion at the altitude of 4,350 m.
Topics: Adult; Altitude; Altitude Sickness; Arginine; Citrulline; Cyclic GMP; Female; Humans; Hypoxia; Infusions, Intravenous; Linear Models; Male; Nitric Oxide; Oxygen; Radioimmunoassay; Reference Values; Time Factors | 2001 |
Neuronal and glial coexpression of argininosuccinate synthetase and inducible nitric oxide synthase in Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Arginine; Argininosuccinate Synthase; Citrulline; Encephalitis; Entorhinal Cortex; Frontal Lobe; Glial Fibrillary Acidic Protein; Hippocampus; Humans; Neuroglia; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peptide Fragments | 2001 |
Augmented age-associated innate immune responses contribute to negative inotropic and lusitropic effects of lipopolysaccharide and interferon gamma.
Topics: Adrenergic beta-Agonists; Age Factors; Aging; Animals; Arginine; Blotting, Western; Citrulline; Cyclic AMP; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunity; Interferon-gamma; Isoproterenol; Lipopolysaccharide Receptors; Lipopolysaccharides; Lysine; Nitric Oxide; Rats; Rats, Wistar; Sepsis; Signal Transduction; Up-Regulation | 2001 |
GABA, taurine and learning: release of amino acids from slices of chick brain following filial imprinting.
Topics: Animals; Animals, Newborn; Arginine; Aspartic Acid; Behavior, Animal; Calcium; Cell Membrane; Chickens; Chromatography, High Pressure Liquid; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Imprinting, Psychological; Membrane Potentials; Neurons; Neuropsychological Tests; Potassium Chloride; Taurine; Telencephalon | 2001 |
Calculated background elimination in quantifying nitric-oxide synthase enzyme activity.
Topics: Arginine; Biochemistry; Citrulline; Humans; Models, Theoretical; Nitric Oxide Synthase; Temperature | 2001 |
L-citrulline mediated relaxation in the control and lipopolysaccharide-treated rat aortic rings.
Topics: Animals; Aorta; Arginine; Citrulline; Corticosterone; Cyclic GMP; Cycloheximide; Glutamine; Guanidines; In Vitro Techniques; Lipopolysaccharides; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilation | 2001 |
Citrulline is not the major product using the standard "NOS activity" assay on renal cortical homogenates.
Topics: Animals; Antioxidants; Arginine; Biopterins; Calcium; Carbon Radioisotopes; Chelating Agents; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Citrulline; Egtazic Acid; Enzyme Inhibitors; Female; Guanidines; Humans; Kidney Cortex; Male; Mice; Mice, Inbred Strains; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Placenta; Rats; Rats, Long-Evans; Tritium | 2002 |
Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway.
Topics: Animals; Aorta; Arginine; Calcium Signaling; Cells, Cultured; Chromones; Citrulline; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Hydrogen Peroxide; Kinetics; Morpholines; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Phosphothreonine; Quinazolines; Signal Transduction; Swine; Tyrphostins | 2002 |
Low exhaled nitric oxide and a polymorphism in the NOS I gene is associated with acute chest syndrome.
Topics: Acute Disease; Adolescent; Anemia, Sickle Cell; Arginine; Breath Tests; Child; Citrulline; Forced Expiratory Volume; Genotype; Humans; Lung Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Polymorphism, Genetic; Syndrome; Trinucleotide Repeats; Vital Capacity | 2001 |
Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans.
Topics: Amino Acid Sequence; Animals; Arginine; Biopterins; Catalysis; Citrulline; Cloning, Molecular; Dimerization; Dithiothreitol; Dose-Response Relationship, Drug; Electrons; Heme; Hydrogen Peroxide; Kinetics; Ligands; Models, Chemical; Models, Molecular; Molecular Sequence Data; NADP; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Thermus; Time Factors; Zinc | 2002 |
L-arginine-nitric oxide pathway in end-stage renal disease.
Topics: Arginine; Citrulline; Humans; Kidney Failure, Chronic; Nitric Oxide; Renal Dialysis; Signal Transduction | 2002 |
Cardiac-specific overexpression of inducible nitric oxide synthase does not result in severe cardiac dysfunction.
Topics: Amino Acid Transport Systems; Animals; Arginine; Argininosuccinate Synthase; Citrulline; Echocardiography; Female; Gene Expression; Gene Expression Regulation, Enzymologic; Heart Failure; Hemodynamics; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity | 2002 |
Renal arginine and protein synthesis are increased during early endotoxemia in mice.
Topics: Amino Acids; Ammonia; Animals; Arginine; Citrulline; Endotoxemia; Female; Kidney; Lipopolysaccharides; Mice; Nitrates; Nitric Oxide; Protein Biosynthesis; Urea | 2002 |
Deimination of arginine residues in nucleophosmin/B23 and histones in HL-60 granulocytes.
Topics: Arginine; Calcimycin; Citrulline; Electrophoresis, Gel, Two-Dimensional; Granulocytes; Histones; HL-60 Cells; Humans; Hydrolases; Immunoblotting; Immunohistochemistry; Ionophores; Kinetics; Nuclear Proteins; Nucleophosmin; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases | 2002 |
Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity.
Topics: Anemia, Sickle Cell; Animals; Arginine; Citrulline; Disease Models, Animal; Erythrocyte Count; Erythrocytes; Hemoglobins; Humans; Kinetics; Mice; Mice, Transgenic; Oxygen; Potassium; Potassium Channels, Calcium-Activated | 2002 |
Perferryl complex of nitric oxide synthase: role in secondary free radical formation.
Topics: Arginine; Binding Sites; Carbon Radioisotopes; Citrulline; Electron Spin Resonance Spectroscopy; Ethanol; Free Radicals; Heme; Humans; Iron; NADP; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidation-Reduction; Potassium Compounds; Recombinant Proteins; Sodium Cyanide; Spin Trapping; Sulfates | 2002 |
Recognition and invasion of human skin by Schistosoma mansoni cercariae: the key-role of L-arginine.
Topics: Animals; Arginine; Chemotaxis; Citrulline; Female; Humans; Mice; Nitric Oxide; Parasitemia; Schistosoma mansoni; Schistosomiasis mansoni; Skin | 2002 |
A brain nitric oxide synthase study in the rat: production of a nitroso-compound NA and absence of nitric oxide synthesis.
Topics: Animals; Arginine; Brain; Citrulline; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nitroso Compounds; Rats | 2002 |
Complementary distribution of NADPH-diaphorase and l-arginine in the snail nervous system.
Topics: Animals; Arginine; Calcium; Citrulline; Ganglia, Invertebrate; Helix, Snails; Homeostasis; NADPH Dehydrogenase; Neurons; Nitric Oxide; Nitric Oxide Synthase | 2002 |
Novel lipoic acid analogues that inhibit nitric oxide synthase.
Topics: Animals; Antioxidants; Arginine; Cell Death; Cell Line; Cell Survival; Citrulline; Drug Design; Enzyme Inhibitors; Glutamic Acid; Glutathione; Mice; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Thioctic Acid | 2002 |
The 'intestinal-renal' arginine biosynthetic axis in the aging rat.
Topics: Aging; Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbamoyl-Phosphate Synthase (Ammonia); Cerebellum; Citrulline; Female; Glutaminase; Intestine, Small; Kidney; Kidney Cortex; Male; Ornithine Carbamoyltransferase; Rats; Rats, Sprague-Dawley | 2002 |
The influence of nitric oxide on basal and cholecystokinin-8-induced proliferation and apoptosis in the rat pancreas.
Topics: Amylases; Animals; Apoptosis; Arginine; Caspases; Cell Division; Cholecystokinin; Citrulline; DNA; Male; Nitric Oxide; Nitroarginine; Organ Size; Pancreas; Peptide Fragments; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine | 2002 |
A case of acrodermatitis enteropathica-like dermatosis caused by ornithine transcarbamylase deficiency.
Topics: Acrodermatitis; Arginine; Citrulline; Diagnosis, Differential; Diaper Rash; Diet, Protein-Restricted; Facial Dermatoses; Female; Humans; Infant; Ornithine Carbamoyltransferase Deficiency Disease; Peritoneal Dialysis; Sodium Benzoate | 2002 |
Recombinant arginine deiminase as a potential anti-angiogenic agent.
Topics: Angiogenesis Inhibitors; Arginine; Cell Division; Cell Movement; Cells, Cultured; Citrulline; Dose-Response Relationship, Drug; Endothelium, Vascular; Escherichia coli; Humans; Hydrolases; Microcirculation; Mutagenesis, Site-Directed; Mycoplasma; Recombinant Proteins; Umbilical Veins | 2002 |
[The role of L-arginine and L-citrulline in activated macrophage against Toxoplasma gondii infection in vitro].
Topics: Animals; Arginine; Cells, Cultured; Citrulline; Female; Macrophage Activation; Macrophages, Peritoneal; Mice; Nitric Oxide; Toxoplasma | 1998 |
Nitric oxide synthase activity in hyperthyroid and hypothyroid rats.
Topics: Animals; Aorta; Arginine; Brain; Citrulline; Hyperthyroidism; Hypothyroidism; Kidney; Male; Myocardium; Nitric Oxide Synthase; Rats; Rats, Wistar; Tritium; Venae Cavae | 2002 |
Evidence for the involvement of L-citrulline but not nitric oxide in the proconvulsant action of the precursor L-arginine on picrotoxin-induced convulsions in rats.
Topics: Animals; Arginine; Citrulline; Disease Models, Animal; Epilepsy; Male; Nitric Oxide; Rats; Rats, Wistar | 2002 |
Improving the prenatal diagnosis of citrullinemia using citrulline/ornithine+arginine ratio in amniotic fluid.
Topics: Amniocentesis; Amniotic Fluid; Arginine; Argininosuccinate Synthase; Chorionic Villi Sampling; Citrulline; Citrullinemia; Female; Humans; Ornithine; Pregnancy; Sensitivity and Specificity | 2002 |
Dinitrobenzene-mediated production of peroxynitrite by neuronal nitric oxide synthase.
Topics: Animals; Arginine; Catalysis; Citrulline; Dinitrobenzenes; Electron Transport; Isomerism; NADP; Neurons; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Rats; Superoxides | 2002 |
Neuronal nitric oxide synthase modulates basal catecholamine secretion in bovine chromaffin cells.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Blotting, Western; Catecholamines; Cattle; Cell Culture Techniques; Chromaffin Cells; Citrulline; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Guanylate Cyclase; Isoenzymes; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phosphodiesterase Inhibitors; Purinones; Thiourea; Time Factors | 2002 |
The activation of neuronal nitric-oxide synthase by various divalent cations.
Topics: Animals; Arginine; Calcium; Carbonates; Cations, Divalent; Citrulline; Electron Spin Resonance Spectroscopy; Enzyme Activation; Kinetics; Lead; Long-Term Potentiation; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Strontium | 2002 |
Intrauterine growth retardation is associated with reduced activity and expression of the cationic amino acid transport systems y+/hCAT-1 and y+/hCAT-2B and lower activity of nitric oxide synthase in human umbilical vein endothelial cells.
Topics: Amino Acid Transport Systems, Basic; Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Cationic Amino Acid Transporter 2; Cells, Cultured; Citrulline; Endothelium, Vascular; Ethylmaleimide; Female; Fetal Growth Retardation; Gene Expression Regulation; Humans; Lysine; Membrane Potentials; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pregnancy; RNA, Messenger; Umbilical Veins | 2002 |
Inhibition of superoxide generation from neuronal nitric oxide synthase by heat shock protein 90: implications in NOS regulation.
Topics: Animals; Arginine; Cell Line; Citrulline; Electron Spin Resonance Spectroscopy; HSP90 Heat-Shock Proteins; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Recombinant Proteins; Superoxides; Time Factors; Xanthine Oxidase | 2002 |
Ruthenium(III) readily abstracts NO from L-arginine, the physiological precursor to NO, in the presence of H2O2. A remarkably simple model system for NO synthases.
Topics: Arginine; Citrulline; Hydrogen Peroxide; Nitric Oxide; Nitric Oxide Synthase; Ruthenium; Ruthenium Compounds | 2001 |
Inducible nitric oxide synthase is expressed in synovial fluid granulocytes.
Topics: Adult; Aged; Arginine; Arthritis, Rheumatoid; Autoimmune Diseases; Blood Cells; Chromatography, High Pressure Liquid; Citrulline; Colorimetry; Enzyme Induction; Exudates and Transudates; Female; Granulocytes; Humans; Knee; Male; Membrane Proteins; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Organ Specificity; Synovial Fluid | 2002 |
Can the nitrogenous composition of xylem sap be used to assess salinity stress in Casuarina glauca?
Topics: Arginine; Asparagine; Citrulline; Glutamine; Hamamelidaceae; Nitrogen Compounds; Plant Stems; Proline; Queensland; Rain; Soil; Trees; Water | 2002 |
L-Arginine supplementation enhances diabetic wound healing: involvement of the nitric oxide synthase and arginase pathways.
Topics: Amino Acids; Animals; Arginase; Arginine; Blood Glucose; Blood Proteins; Body Weight; Citrulline; Diabetes Complications; Hydroxyproline; Male; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Wound Healing; Wounds and Injuries | 2002 |
Coupling sap flow velocity and amino acid concentrations as an alternative method to (15)N labeling for quantifying nitrogen remobilization by walnut trees.
Topics: Amino Acids; Arginine; Aspartic Acid; Biological Transport; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Juglans; Light; Nitrogen; Nitrogen Isotopes; Plant Shoots; Rheology; Seasons; Time Factors | 2002 |
Comparative survey in Lactobacillus plantarum of the growth and metabolism of arginine and citrulline in different media.
Topics: Arginine; Base Sequence; Beverages; Citrulline; Citrus; Culture Media; DNA, Ribosomal; Hydrolases; Lactobacillus; Molecular Sequence Data; Ornithine Carbamoyltransferase; RNA, Ribosomal, 16S; Solanum lycopersicum | 2002 |
The antithyroid agent 6-n-propyl-2-thiouracil is a mechanism-based inactivator of the neuronal nitric oxide synthase isoform.
Topics: Animals; Antithyroid Agents; Arginine; Biopterins; Calcium; Calmodulin; Carbon Monoxide; Carbon Radioisotopes; Citrulline; Enzyme Activation; Enzyme Inhibitors; Heme; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pituitary Neoplasms; Propylthiouracil; Rats; Thiouracil; Tumor Cells, Cultured | 2002 |
Cerebrospinal fluid and plasma concentrations of nitric oxide metabolites are increased in dementia with Lewy bodies.
Topics: Aged; Arginine; Citrulline; Female; Humans; Lewy Body Disease; Male; Nitrates; Nitrites | 2002 |
Lack of a role of neuronal nitric oxide synthase in the regulation of the renal function in rats fed a low-sodium diet.
Topics: Animals; Arginine; Blood Pressure; Citrulline; Diet, Sodium-Restricted; Enzyme Inhibitors; Glomerular Filtration Rate; Kidney; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Organ Size; Rats; Rats, Sprague-Dawley; Renal Plasma Flow; Renin; RNA, Messenger; Sodium; Thiourea; Urodynamics | 2002 |
L-citrulline recycling by argininosuccinate synthetase and lyase in rat gastric fundus.
Topics: Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Argininosuccinic Acid; Aspartic Acid; Citrulline; Dinoprost; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; Glutamic Acid; Glutamine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Thiolester Hydrolases; Ubiquitin Thiolesterase | 2002 |
Haemorheological and endothelial-dependent alterations in heart failure after ACE inhibitor, calcium antagonist and beta blocker.
Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Arginine; Blood Viscosity; Calcium; Carbazoles; Carvedilol; Citrulline; Erythrocytes; Female; Fibrinogen; Heart Failure; Humans; Male; Middle Aged; Nitric Oxide Synthase; Propanolamines; Ramipril; Time Factors; Treatment Outcome; Vascular Cell Adhesion Molecule-1; Vasodilator Agents | 2002 |
Synthesis and characterization of nitric oxide generative polyrotaxane.
Topics: alpha-Cyclodextrins; Arginine; Biocompatible Materials; Citrulline; Cyclodextrins; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Poloxamer; Rotaxanes | 2002 |
Effect of cardiopulmonary bypass on urea cycle intermediates and nitric oxide levels after congenital heart surgery.
Topics: Arginine; Blood Urea Nitrogen; Cardiopulmonary Bypass; Citrulline; Female; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Male; Nitric Oxide; Ornithine; Urea | 2003 |
Effect of arginine, ornithine and citrulline supplementation upon performance and metabolism of trained rats.
Topics: Ammonia; Animals; Arginine; Citrulline; Dietary Supplements; Glutamate-Ammonia Ligase; Glutamine; Glycogen; Liver; Male; Muscle, Skeletal; Ornithine; Rats; Rats, Wistar; Swimming; Urea | 2003 |
Induction of citrulline-nitric oxide (NO) cycle enzymes and NO production in immunostimulated rat RPE-J cells.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Cell Culture Techniques; Cell Line; Citrulline; Cyclic AMP; Dexamethasone; Enzyme Induction; Gene Expression Regulation, Enzymologic; Glucocorticoids; Interferon-gamma; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; Pigment Epithelium of Eye; Rats; RNA, Messenger; Tumor Necrosis Factor-alpha | 2003 |
Resistance to the anti-proliferative activity of recombinant arginine deiminase in cell culture correlates with the endogenous enzyme, argininosuccinate synthetase.
Topics: Animals; Arginine; Argininosuccinate Synthase; Cell Division; Cell Line; Cell Survival; Citrulline; Cricetinae; Dogs; Drug Resistance; Humans; Hydrolases; Mice; Mycoplasma; Recombinant Proteins | 2003 |
Selective stabilization of the chorismate mutase transition state by a positively charged hydrogen bond donor.
Topics: Alanine; Amino Acid Substitution; Arginine; Bacillus subtilis; Cations; Chorismate Mutase; Citrulline; Enzyme Stability; Escherichia coli; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Fusion Proteins | 2003 |
Role of endogenous nitric oxide in unilateral ureteropelvic junction obstruction in children.
Topics: Arginine; Child; Child, Preschool; Citrulline; Female; Gene Expression Regulation, Enzymologic; Humans; Immunohistochemistry; Infant; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; RNA, Messenger; Tritium; Ureteral Obstruction | 2003 |
Treatment of ammonia intoxication in rats with urea cycle amino acids, furosemide and fluids.
Topics: Ammonia; Animals; Arginine; Citrulline; Diuretics; Fluid Therapy; Furosemide; Male; Ornithine; Poisoning; Rats; Rats, Wistar | 2003 |
Arginine deprivation and tumour cell death: arginase and its inhibition.
Topics: Animals; Arginase; Arginine; Cattle; Cell Death; Cell Division; Cell Line; Citrulline; Dose-Response Relationship, Drug; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Mice; Ornithine; Time Factors; Valine | 2003 |
Cyanide binding study of neuronal nitric oxide synthase: effects of inhibitors and mutations at the substrate binding site.
Topics: Arginine; Binding Sites; Citrulline; Cyanides; Enzyme Inhibitors; Indazoles; Mutagenesis, Site-Directed; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Spectrophotometry, Ultraviolet; Thiourea | 2003 |
Computational docking of L-arginine and its structural analogues to C-terminal domain of Escherichia coli arginine repressor protein (ArgRc).
Topics: Arginine; Binding Sites; Canavanine; Citrulline; Computer Simulation; Crystallization; Escherichia coli Proteins; Homoarginine; Lysine; Models, Molecular; Molecular Structure; Protein Binding; Protein Conformation; Repressor Proteins | 2003 |
Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrolase I and increases nitric oxide synthase activity in vascular endothelial cells.
Topics: Animals; Arginine; Biopterins; Blotting, Northern; Brain; Cells, Cultured; Citrulline; DNA Primers; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; GTP Cyclohydrolase; Hydrogen Peroxide; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidants; Reverse Transcriptase Polymerase Chain Reaction | 2003 |
Extent of genetic lesions of the arginine and pyrimidine biosynthetic pathways in Lactobacillus plantarum, L. paraplantarum, L. pentosus, and L. casei: prevalence of CO(2)-dependent auxotrophs and characterization of deficient arg genes in L. plantarum.
Topics: Arginine; Carbamyl Phosphate; Carbon Dioxide; Citrulline; Codon, Nonsense; Culture Media; Evolution, Molecular; Genes, Bacterial; Humans; Lacticaseibacillus casei; Lactobacillus; Mutation; Ornithine; Phenotype; Pyrimidines; Species Specificity | 2003 |
Impairment of vascular endothelial nitric oxide synthase activity by advanced glycation end products.
Topics: Animals; Antibodies; Aorta; Arginine; Blood Pressure; Cells, Cultured; Citrulline; Diabetes Mellitus; Endothelium, Vascular; Enzyme Inhibitors; Female; Femoral Artery; Glycation End Products, Advanced; Humans; In Vitro Techniques; Lysine; Male; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rabbits; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Vasodilation | 2003 |
Neuroprotective kappa-opioid receptor agonist BRL 52537 attenuates ischemia-evoked nitric oxide production in vivo in rats.
Topics: Animals; Arginine; Cerebral Infarction; Citrulline; Corpus Striatum; Disease Models, Animal; Ischemic Attack, Transient; Male; Microdialysis; Neuroprotective Agents; Nitric Oxide; Piperidines; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Treatment Outcome | 2003 |
The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms.
Topics: Amino Acid Transport Systems, Basic; Arginine; Biological Transport; Carrier Proteins; Citrulline; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Humans; Hyperammonemia; Kinetics; Liposomes; Liver; Lysine; Malates; Membrane Transport Proteins; Mitochondria; Models, Biological; Mutation; Ornithine; Phosphates; Protein Folding; Protein Isoforms; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity; Time Factors; Tissue Distribution; Transcription, Genetic | 2003 |
Cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1*0401 MHC class II molecule.
Topics: Alleles; Animals; Arginine; Arthritis, Experimental; Arthritis, Rheumatoid; Cells, Cultured; Citrulline; HLA-DR Antigens; HLA-DR4 Antigen; HLA-DRB1 Chains; Humans; Lymphocyte Activation; Mice; Mice, Transgenic; Peptide Fragments; Protein Binding; Protein Processing, Post-Translational; T-Lymphocytes; Vimentin | 2003 |
Characterization of suppression of nitric oxide production by carbon monoxide poisoning in the striatum of free-moving rats, as determined by in vivo brain microdialysis.
Topics: Animals; Arginine; Carbon Monoxide Poisoning; Citrulline; Corpus Striatum; Extracellular Space; Isomerism; Male; Microdialysis; Movement; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley | 2003 |
Heat shock protein 90 as an endogenous protein enhancer of inducible nitric-oxide synthase.
Topics: Allosteric Site; Amino Acid Sequence; Animals; Arginine; Blotting, Western; Cell Line; Citrulline; COS Cells; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Escherichia coli; HSP90 Heat-Shock Proteins; Humans; Macrophages; Mice; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Precipitin Tests; Protein Binding; Protein Processing, Post-Translational; Recombinant Proteins; Sequence Homology, Amino Acid; Spin Trapping; Transcription, Genetic; Transfection | 2003 |
Oral supplementation corrects plasma lysine concentrations in lysinuric protein intolerance.
Topics: Absorption; Adult; Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Citrulline; Female; Humans; Intestinal Absorption; Kidney Tubules; Kinetics; Lysine; Male; Nitrogen; Ornithine; Reference Values; Urea | 2003 |
Influence of dietary arginine on sexual dimorphism of arginine metabolism in mice.
Topics: Animals; Arginase; Arginine; Citrulline; Creatinine; Diet; Female; Kidney; Male; Mice; Muscle, Skeletal; Nitric Oxide Synthase; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Orotic Acid; Putrescine; Sex Characteristics; Urea | 2003 |
Arginine deprivation, growth inhibition and tumour cell death: 3. Deficient utilisation of citrulline by malignant cells.
Topics: Arginine; Argininosuccinate Synthase; Cell Death; Cell Division; Citrulline; Humans; Tumor Cells, Cultured | 2003 |
Cauda equina syndrome and nitric oxide synthase immunoreactivity in the spinal cord of the dog.
Topics: Animals; Arginine; Catalysis; Citrulline; Dogs; Female; Immunohistochemistry; Male; NADPH Dehydrogenase; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Polyradiculopathy; Radioimmunoassay; Spinal Cord | 2003 |
[Arginine deaminase and the enzymatic formation of citrulline by yeasts].
Topics: Amidohydrolases; Aminohydrolases; Arginine; Citrulline; Saccharomyces cerevisiae; Yeast, Dried; Yeasts | 1952 |
Proline: synthesis from ornithine, citrulline, or arginine.
Topics: Arginine; Citrulline; Ornithine; Proline | 1952 |
The arginine dihydrolase system of Streptococcus faecalis. I. Identification of citrulline as an intermediate.
Topics: Arginine; Citrulline; Enterococcus faecalis; Humans; Hydrolases; Streptococcus | 1952 |
[Argininedesiminase and the enzymatic formation of citrulline by yeast].
Topics: Arginine; Biochemical Phenomena; Citrulline; Enzymes; Saccharomyces cerevisiae; Yeasts | 1952 |
Biosynthesis of urea. IV. Further studies on condensation in arginine synthesis from citrulline.
Topics: Arginine; Citrulline; Urea | 1953 |
The mechanism of arginine synthesis from citrulline in kidney.
Topics: Arginine; Citrulline; Kidney | 1953 |
[The biosynthesis of arginine phosphate from citrulline].
Topics: Amino Acids; Arginine; Citrulline; Organophosphorus Compounds; Phosphates | 1954 |
Urea synthesis and metabolism of arginine and citrulline.
Topics: Amino Acids; Arginine; Citrulline; Urea | 1954 |
The effects of arginine, ornithine and citrulline on the growth of Drosophila.
Topics: Amino Acids; Animals; Arginine; Citrulline; Diptera; Drosophila; Ornithine | 1956 |
Conversion of argininosuccinic acid to citrulline coupled to ATP formation.
Topics: Adenosine Triphosphate; Amino Acids; Arginine; Argininosuccinic Acid; Citrulline; Liver; Succinates | 1956 |
Growth response of stable and primary cell cultures to L-ornithine, L-citrulline, and L-arginine.
Topics: Amino Acids; Arginine; Citrulline; Ornithine; Primary Cell Culture; Tissue Culture Techniques | 1960 |
On the relation of inflammation to the chemical constitution of injurious agents. On the pharmacology of inflammation.
Topics: Acids; Alkalies; Arginine; Citrulline; Electrolytes; Histamine; Inflammation; Proteins | 1963 |
Determination of ornithine, lysine, arginine, citrulline and histidine.
Topics: Amino Acids; Arginine; Chromatography; Citrulline; Histidine; Lysine; Ornithine | 1963 |
RESPONSE OF JENSEN SARCOMA CELL CULTURES TO SOME ANALOGS, HOMOLOGS, AND PEPTIDES OF ARGININE, ORNITHINE, AND CITRULLINE.
Topics: Amino Acids; Animals; Arginine; Cell Culture Techniques; Citrulline; Histocytochemistry; Ornithine; Peptides; Research; Sarcoma; Sarcoma, Experimental; Tissue Culture Techniques | 1963 |
A STUDY OF ORNITHINE, CITRULLINE AND ARGININE SYNTHESIS IN GROWING CHICKS.
Topics: Amino Acids; Animals; Arginine; Benzoates; Blood Chemical Analysis; Carbonates; Chickens; Citrulline; Glutamates; Intestines; Kidney; Liver; Muscles; Myocardium; Ornithine; Poultry; Proteins; Research; Spleen; Uric Acid | 1963 |
[RADIOACTIVE CARBON LABELED AMINO ACIDS OF THE KREBS CYCLE].
Topics: Amino Acids; Arginine; Carbon; Carbon Isotopes; Citric Acid Cycle; Citrulline; Ornithine; Radioactivity; Research | 1963 |
ENZYMES OF ARGININE METABOLISM IN MAMMALIAN CELL CULTURE. I. REPRESSION OF ARGININOSUCCINATE SYNTHETASE AND ARGININOSUCCINASE.
Topics: Amino Acids; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbon Dioxide; Carbon Isotopes; Chromatography; Citrulline; Connective Tissue; Genetics; Histidine; Ligases; Lyases; Mice; Ornithine; Phosphotransferases; Proteins; Research; Tissue Culture Techniques | 1964 |
[INITIAL CLINICAL RESULTS FOLLOWING THE USE OF A NEW HEPATOPROTECTIVE AND ANTI-BLOOD AMMONIA PREPARATION].
Topics: Amino Acids; Ammonia; Arginine; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Citrulline; Geriatrics; Hepatitis; Hepatitis A; Humans; Ornithine | 1963 |
MENTAL RETARDATION AND THE INBORN ERRORS OF METABOLISM.
Topics: Alkaptonuria; Amino Acid Metabolism, Inborn Errors; Arginine; Citrulline; Fructose; Galactosemias; Histidine; Homocysteine; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Maple Syrup Urine Disease; Metabolic Diseases; Phenylketonurias; Renal Aminoacidurias; Vitamin B 6 Deficiency | 1964 |
[DETERMINATION OF THE AMINO ACIDS OF THE UREOPOIETIC CYCLE OF KREBS-HENSELEIT: L-ARGININE, L-ORNITHINE AND L-CITRULLINE].
Topics: Amino Acids; Antifibrinolytic Agents; Arginine; Chemistry Techniques, Analytical; Citrulline; Ornithine; Research | 1964 |
INDUCIBLE TRANSPORT SYSTEM FOR CITRULLINE IN STREPTOCOCCUS FAECALIS.
Topics: Amino Acids; Arginine; Bacteriological Techniques; Biological Transport; Citrulline; Culture Media; Enterococcus faecalis; Manometry; Nitrogen; Permeability; Research; Spectrophotometry; Ultrasonics | 1964 |
[REMARKS ON ISATIN-BETA-THIOSEMICARBAZONE AND ON SEVERAL INHIBITORS OF VIRAL DEVELOPMENT].
Topics: Antiviral Agents; Arginine; Citrulline; Creatine; Creatinine; Enterovirus C, Human; Glutamine; Glycine; Guanidine; Guanidines; Indoles; Isatin; Mutation; Ornithine; Pharmacology; Poliovirus; Thiosemicarbazones; Thiourea; Uracil; Urea | 1964 |
[CLINICAL OBSERVATIONS ON THE THERAPEUTIC EFFECTIVENESS OF AN ASSOCIATION OF ANTITOXIC HEPATIC EXTRACT, ARGININE HYDROCHLORIDE, ORNITHINE HYDROCHLORIDE AND CITRULLINE IN PATIENTS WITH LIVER DISEASES].
Topics: Amino Acids; Arginine; Blood Coagulation; Blood Proteins; Citrulline; Humans; Liver Cirrhosis; Liver Diseases; Liver Extracts; Liver Function Tests; Ornithine; Pharmacology | 1964 |
PHYSIOLOGY OF THE SPORULATION PROCESS IN CLOSTRIDIUM BOTULINUM. II. MATURATION OF FORESPORES.
Topics: Acetates; Alanine; Amino Acids; Arginine; Carbon Dioxide; Carbon Isotopes; Citrulline; Clostridium botulinum; DNA; DNA, Bacterial; Fatty Acids; Fermentation; Hot Temperature; Isoleucine; Metabolism; Ornithine; Phosphorus Isotopes; Picolinic Acids; Proline; Research; RNA; RNA, Bacterial; Spores; Spores, Bacterial | 1964 |
EFFECTS OF BICARBONATE ON GROWTH OF PASTEURELLA PESTIS. 3. REPLACEMENT OF BICARBONATE BY PYRIMIDINES.
Topics: Arginine; Bicarbonates; Carbamates; Carbon Dioxide; Citrulline; Culture Media; Cytosine; Metabolism; Orotic Acid; Pharmacology; Phosphates; Pyrimidines; Research; Uracil; Yersinia pestis | 1964 |
THE ASSIMILATION OF ARGININE AND LYSINE IN CANAVANINE RESISTANT AND SENSITIVE STRAINS OF NEUROSPORA CRASSA.
Topics: Amino Acids; Arginine; Biochemical Phenomena; Canavanine; Carbon Isotopes; Citrulline; Lysine; Neurospora; Neurospora crassa; Ornithine; Research; Serine | 1964 |
THE EFFECT OF AMMONIA ADMINISTRATION ON OROTIC ACID EXCRETION IN RATS.
Topics: Ammonia; Ammonium Chloride; Antimetabolites; Arginine; Chromatography; Citrulline; Diet; Glutamine; Ornithine; Orotic Acid; Pharmacology; Rats; Research; Succinates; Urine | 1965 |
KERATIN IN MONILETHRIX.
Topics: Arginine; Citrulline; Hair; Histocytochemistry; Humans; Keratins; Metabolic Diseases; Monilethrix | 1965 |
EFFECTS OF SOME AMINO ACIDS ON THE INHIBITION OF PLASMIN BY ANTIPLASMIN.
Topics: Amino Acids; Aminobutyrates; Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Arginine; Citrulline; Enzyme Inhibitors; Fatty Acids; Fibrinolysin; Kinetics; Lysine; Ornithine; Research | 1965 |
APPARENT INDUCTION OF ORNITHINE TRANSCARBAMYLASE AND ARGINASE BY ARGININE IN BACILLUS LICHENIFORMIS.
Topics: Amino Acids; Arginase; Arginine; Bacillus; Citrulline; Colorimetry; Culture Media; Enzyme Repression; Glutamates; Ornithine; Ornithine Carbamoyltransferase; Research | 1965 |
ARGININE AND UREA BIOSYNTHESIS IN THE EARTHWORM LUMBRICUS TERRESTRIS.
Topics: Amino Acids; Animals; Annelida; Arginine; Bicarbonates; Chromatography; Citrulline; Intestines; Ligases; Lyases; Oligochaeta; Ornithine; Ornithine Carbamoyltransferase; Research; Starvation; Urea | 1965 |
Depletion of serum L-arginine in patients with acute pancreatitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Alcoholism; Amylases; Arginine; C-Reactive Protein; Cholecystitis, Acute; Citrulline; Female; Gallstones; Humans; Male; Middle Aged; Nitrates; Nitrites; Pancreatitis; Pancreatitis, Alcoholic; Recurrence; Time Factors | 2003 |
Role of neutral amino acid transport and protein breakdown for substrate supply of nitric oxide synthase in human endothelial cells.
Topics: Amino Acid Transport Systems, Neutral; Amino Acids; Amino Acids, Neutral; Animals; Arginine; Biological Transport; Carcinoma; Cells, Cultured; Citrulline; Endothelium, Vascular; Glutamine; Humans; Intracellular Fluid; Membrane Transport Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Proteins; Rats; Substrate Specificity; Transfection; Umbilical Veins; Urinary Bladder Neoplasms | 2003 |
Inhibitory effects and spectral interactions of isomeric methoxyindazoles on recombinant nitric oxide synthases.
Topics: Arginine; Citrulline; Cytochromes c; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Indazoles; Isoenzymes; NADP; Nitric Oxide Synthase; Recombinant Proteins; Spectrophotometry, Ultraviolet | 2003 |
A decrease in glucose production is associated with an increase in plasma citrulline response to oral arginine in normal volunteers.
Topics: Adult; Alanine; Arginine; Biomarkers; Blood Glucose; Body Mass Index; C-Peptide; Citrulline; Female; Glucose; Humans; Insulin; Liver; Male; Middle Aged; Nitric Oxide | 2003 |
Long-term outcome of patients with urea cycle disorders and the question of neonatal screening.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Arginine; Argininosuccinic Acid; Child; Citrulline; Diet; False Positive Reactions; Humans; Hyperammonemia; Infant, Newborn; Intellectual Disability; Metabolism, Inborn Errors; Neonatal Screening; Retrospective Studies; Treatment Outcome; Urea | 2003 |
Myeloperoxidase up-regulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition.
Topics: Animals; Arginine; Catalysis; Chromatography, High Pressure Liquid; Citrulline; Electrochemistry; Escherichia coli; Feedback, Physiological; Hydrogen Peroxide; Inflammation; Kinetics; Mice; Milk; Models, Biological; Models, Chemical; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxygen; Peroxidase; Protein Binding; RNA, Messenger; Spectrophotometry; Time Factors; Ultraviolet Rays; Up-Regulation | 2003 |
Expression analysis of putative arcA, arcB and arcC genes partially cloned from Lactobacillus plantarum isolated from wine.
Topics: Amino Acid Sequence; Ammonia; Arginine; Bacterial Outer Membrane Proteins; Citrulline; Cloning, Molecular; Escherichia coli Proteins; Fermentation; Gene Expression Regulation; Genes, Bacterial; Humans; Lactobacillus; Membrane Proteins; Molecular Sequence Data; Protein Kinases; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Wine | 2004 |
Expression of nitric oxide synthase and effect of substrate manipulation of the nitric oxide pathway in mouse ovarian follicles.
Topics: Animals; Arginine; Citrulline; Culture Media; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Mice; Mice, Inbred Strains; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ovarian Follicle; Ovulation; RNA, Messenger; Tissue Survival; Transferrin | 2004 |
Pertussis toxin activates L-arginine uptake in pulmonary endothelial cells through downregulation of PKC-alpha activity.
Topics: Animals; Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Cells, Cultured; Citrulline; Colforsin; Cyclic AMP; Endothelium, Vascular; Enzyme Inhibitors; Pertussis Toxin; Protein Kinase C; Protein Kinase C-alpha; Pulmonary Artery; Swine; Thionucleotides | 2004 |
Relationship between carbamoyl-phosphate synthetase genotype and systemic vascular function.
Topics: Adult; Arginine; Bradykinin; Carbamoyl-Phosphate Synthase (Ammonia); Citrulline; Female; Forearm; Genotype; Humans; Male; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Polymorphism, Genetic; Regional Blood Flow; Urea; Vasodilation; Vasodilator Agents | 2004 |
Arginine increases growth hormone gene expression in rat pituitary and GH3 cells.
Topics: Analysis of Variance; Animals; Arginine; Blotting, Northern; Cell Line, Tumor; Citrulline; Dose-Response Relationship, Drug; Drug Combinations; Gene Expression Regulation; Growth Hormone; Male; Ornithine; Pituitary Gland; Rats; Rats, Wistar; RNA, Messenger | 2004 |
IL-10 inhibits nitric oxide synthesis in murine uterus.
Topics: Animals; Arginine; Citrulline; Dose-Response Relationship, Drug; Down-Regulation; Estrogens; Female; Interleukin-10; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Pregnancy; Uterus | 2004 |
Preparation of D-ornithine, D-citrulline, and D-arginine.
Topics: Amino Acids; Arginine; Citrulline; Humans; Ornithine | 1951 |
Biosynthesis of urea. III. Further studies on arginine synthesis from citrulline.
Topics: Arginine; Citrulline; Enzymes; Urea | 1951 |
Argininosuccinate synthase expression is required to maintain nitric oxide production and cell viability in aortic endothelial cells.
Topics: Animals; Aorta; Apoptosis; Arginine; Argininosuccinate Synthase; Cattle; Cell Survival; Citrulline; Endothelium, Vascular; Gene Silencing; Nitric Oxide; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering | 2004 |
Toxoplasma gondii lacks the enzymes required for de novo arginine biosynthesis and arginine starvation triggers cyst formation.
Topics: Animals; Arginine; Cell Line; Citrulline; Fibroblasts; Host-Parasite Interactions; Humans; Life Cycle Stages; Microscopy, Fluorescence; Ornithine; Toxoplasma | 2004 |
In vivo and in vitro evidence for ACh-stimulated L-arginine uptake.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adult; Animals; Aorta; Arginine; Cattle; Cells, Cultured; Citrulline; Endothelium, Vascular; Forearm; Humans; Isoproterenol; Male; Nitric Oxide Donors; Nitroprusside; Regional Blood Flow; Vasodilator Agents | 2004 |
Upregulation of endothelial nitric oxide synthase in rat aorta after ingestion of fish oil-rich diet.
Topics: Animals; Aorta; Arginine; Citrulline; Cyclic GMP; Dietary Fats, Unsaturated; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Fish Oils; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidoreductases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxides; Up-Regulation | 2004 |
Crystal structures of arginine deiminase with covalent reaction intermediates; implications for catalytic mechanism.
Topics: Amino Acid Sequence; Arginine; Citrulline; Crystallography, X-Ray; Hydrolases; Molecular Sequence Data; Mycoplasma; Protein Structure, Tertiary | 2004 |
Adaptative increase of ornithine production and decrease of ammonia metabolism in rat colonocytes after hyperproteic diet ingestion.
Topics: Adaptation, Physiological; Ammonia; Ammonium Chloride; Animals; Arginine; Body Weight; Citrulline; Colon; Dietary Proteins; Dose-Response Relationship, Drug; Eating; Feces; Hydrogen-Ion Concentration; Intestines; Male; Ornithine; Osmolar Concentration; Polyamines; Quaternary Ammonium Compounds; Rats; Rats, Inbred F344; Veins | 2004 |
Spin trapping of nitric oxide with the iron-dithiocarbamate complex: chemistry and biology.
Topics: Arginine; Citrulline; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Iron; Models, Chemical; Nitric Oxide; Nitrogen Oxides; Spin Trapping; Thiocarbamates | 2004 |
Acute reduction of circulating arginine in mice does not compromise whole body NO production.
Topics: Animals; Arginase; Arginine; Citrulline; Kidney; Lipopolysaccharides; Male; Mice; Nitric Oxide; Random Allocation | 2004 |
Application of the linear interaction energy method (LIE) to estimate the binding free energy values of Escherichia coli wild-type and mutant arginine repressor C-terminal domain (ArgRc)-l-arginine and ArgRc-l-citrulline protein-ligand complexes.
Topics: Arginine; Bacterial Proteins; Citrulline; Computer Simulation; Escherichia coli; Escherichia coli Proteins; Models, Molecular; Molecular Structure; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Repressor Proteins; Thermodynamics | 2004 |
Enterocyte metabolism during early adaptation after extensive intestinal resection in a rat model.
Topics: Adaptation, Physiological; Animals; Arginine; Arteries; Body Weight; Cell Separation; Citrulline; Decarboxylation; Enterocytes; Glutaminase; Glutamine; Glutathione; Intestine, Small; Intestines; Male; Ornithine; Ornithine Decarboxylase; Rats; Rats, Wistar | 2004 |
Increased (E)-4-hydroxy-2-nonenal and asymmetric dimethylarginine concentrations and decreased nitric oxide concentrations in the plasma of patients with major depression.
Topics: Aldehydes; Arginine; Citrulline; Coronary Disease; Depressive Disorder, Major; Female; Glutathione; Humans; Lipid Peroxidation; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites | 2004 |
The effect of divalent cations on neuronal nitric oxide synthase activity.
Topics: Arginine; Barium; Cadmium; Calmodulin; Cations, Divalent; Citrulline; Cyclic N-Oxides; Cytochromes c; Indicators and Reagents; Kinetics; Manganese; Nickel; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Reactive Oxygen Species; Spin Trapping; Xanthine Oxidase | 2004 |
A quantitative study of the neuronal nitric oxide synthase expression in the superficial layers of the adult rat superior colliculus after perinatal enucleation.
Topics: Animals; Animals, Newborn; Arginine; Blotting, Western; Citrulline; Densitometry; Eye Enucleation; Functional Laterality; Gene Expression Regulation, Developmental; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Protein Isoforms; Rats; Superior Colliculi; Tritium | 2004 |
Structural basis for Ca(2+)-induced activation of human PAD4.
Topics: Amino Acid Motifs; Arginine; Binding Sites; Cadmium; Calcium; Catalysis; Citrulline; Crystallography, X-Ray; Enzyme Activation; Humans; Hydrolases; Hydrolysis; Ions; Models, Chemical; Models, Molecular; Mutagenesis; Mutation; Polymorphism, Single Nucleotide; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Substrate Specificity | 2004 |
Time course of nitric oxide production after endotoxin challenge in mice.
Topics: Analysis of Variance; Animals; Arginine; Citrulline; Endotoxemia; Glutamine; Injections, Intraperitoneal; Lipopolysaccharides; Male; Mice; Nitric Oxide; Phenylalanine; Radioactive Tracers; Time Factors | 2004 |
Role of adenosine transport in gestational diabetes-induced L-arginine transport and nitric oxide synthesis in human umbilical vein endothelium.
Topics: Adenosine; Adult; Arginine; Cationic Amino Acid Transporter 1; Cells, Cultured; Citrulline; Diabetes, Gestational; Endothelium, Vascular; Female; Humans; Infant, Newborn; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pregnancy; Protein Kinase C; Receptor, Adenosine A2A; RNA, Messenger; Umbilical Veins | 2004 |
Reduced endothelial nitric oxide synthase activity and concentration in fetal umbilical veins from maternal cigarette smokers.
Topics: Adult; Arginine; Citrulline; Endothelial Cells; Endothelium, Vascular; Female; Fetal Growth Retardation; Humans; Immunoenzyme Techniques; Infant, Newborn; Maternal-Fetal Exchange; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pregnancy; Smoking; Umbilical Veins; Vasodilation | 2004 |
Activation of endothelial nitric-oxide synthase by the p38 MAPK in response to black tea polyphenols.
Topics: Adenoviridae; Animals; Aorta; Arginine; Blotting, Western; Calcium; Calmodulin; Catalysis; Citrulline; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genetic Vectors; Imidazoles; Immunoprecipitation; Mutation; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphatidylinositol 3-Kinases; Phosphorylation; Polyphenols; Pyridines; Signal Transduction; Swine; Tea; Time Factors; Transfection | 2004 |
Histone deimination antagonizes arginine methylation.
Topics: Arginine; Cell Line, Tumor; Citrulline; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Histones; Humans; Hydrolases; Imines; Methylation; Promoter Regions, Genetic; Protein Structure, Tertiary; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Protein-Arginine N-Methyltransferases; Proteins; Transcriptional Activation; Trefoil Factor-1; Tumor Suppressor Proteins | 2004 |
Human PAD4 regulates histone arginine methylation levels via demethylimination.
Topics: Amino Acid Sequence; Arginine; Blotting, Western; Calcimycin; Cell Line, Tumor; Citrulline; Gene Expression Regulation; Genes, Reporter; Histones; HL-60 Cells; Humans; Hydrolases; Ionophores; Membrane Proteins; Methylamines; Methylation; Molecular Sequence Data; Presenilin-2; Promoter Regions, Genetic; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Protein-Arginine N-Methyltransferases; Recombinant Fusion Proteins; Recombinant Proteins | 2004 |
Biochemical responses of healthy subjects during dietary supplementation with L-arginine.
Topics: Arginine; Biological Availability; Blood; Blood Glucose; Citrulline; Cyclic GMP; Dietary Supplements; Dose-Response Relationship, Drug; Female; Glycine; Humans; Insulin; Lysine; Male; Ornithine | 2004 |
Urea synthesis by ruminal epithelial and duodenal mucosal cells from growing sheep.
Topics: Ammonia; Animals; Arginase; Arginine; Aspartic Acid; Carbamoyl-Phosphate Synthase (Ammonia); Cells, Cultured; Citrulline; Duodenum; Enzyme Activation; Epithelial Cells; Gastric Mucosa; Intestinal Mucosa; Ornithine; Rumen; Sheep; Urea | 2004 |
Electrostatic interactions dominate the catalytic contribution of arg39 in 4-oxalocrotonate tautomerase.
Topics: Amino Acid Substitution; Arginine; Catalysis; Circular Dichroism; Citrulline; Isomerases; Kinetics; Protein Folding; Static Electricity | 2004 |
Molecular biology: no exception to reversibility.
Topics: Arginine; Chromatin; Citrulline; Gene Silencing; Histones; Humans; Hydrolases; Methylation; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases | 2004 |
Determination of arginine and asymmetric dimethylarginine (ADMA) in human plasma by liquid chromatography/mass spectrometry with the isotope dilution technique.
Topics: Adult; Aged; Arginine; Calibration; Carbon Isotopes; Chromatography, Liquid; Citrulline; Female; Humans; Indicator Dilution Techniques; Kidney Failure, Chronic; Male; Mass Spectrometry; Middle Aged; Plasma; Sensitivity and Specificity | 2004 |
The Influence of a load of L-arginine on serum amino acids and pancreatic apoptosis/proliferation and ATP levels in the rat.
Topics: Adenosine Triphosphate; Amino Acids; Amylases; Animals; Apoptosis; Arginine; Cell Proliferation; Citrulline; DNA; Male; Mitosis; Organ Size; Pancreas; Proteins; Rats; Rats, Wistar; Water | 2004 |
Delta1-pyrroline-5-carboxylate synthase deficiency: neurodegeneration, cataracts and connective tissue manifestations combined with hyperammonaemia and reduced ornithine, citrulline, arginine and proline.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Cataract; Child; Child, Preschool; Citrulline; delta-1-Pyrroline-5-Carboxylate Reductase; Female; Humans; Hyperammonemia; Male; Mutation, Missense; Ornithine; Phenotype; Proline; Pyrroline Carboxylate Reductases | 2005 |
Citrulline increases arginine pools and restores nitrogen balance after massive intestinal resection.
Topics: Amino Acids; Animals; Arginine; Citrulline; Dietary Supplements; Intestinal Mucosa; Intestines; Liver; Male; Muscles; Nitrogen; Rats; Rats, Wistar; Short Bowel Syndrome | 2004 |
Endogenous methylarginines modulate superoxide as well as nitric oxide generation from neuronal nitric-oxide synthase: differences in the effects of monomethyl- and dimethylarginines in the presence and absence of tetrahydrobiopterin.
Topics: Animals; Arginine; Biopterins; Calcium; Calmodulin; Cell Line; Citrulline; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Humans; Magnetics; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Rats; Spin Trapping; Superoxides; Time Factors; Transfection | 2005 |
Accessibility of endothelial and inducible nitric oxide synthase to the intracellular citrulline-arginine regeneration pathway.
Topics: Animals; Arginine; Cells, Cultured; Citrulline; Endothelium, Vascular; Intracellular Fluid; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Signal Transduction | 2005 |
Screening of bitterness-suppressing agents for quinine: the use of molecularly imprinted polymers.
Topics: Arginine; Chromatography, High Pressure Liquid; Citrulline; Drug Evaluation, Preclinical; Drug Interactions; Humans; Lysine; Models, Biological; Models, Molecular; Ornithine; Quinine; Reference Standards; Sweetening Agents; Taste; Taste Threshold | 2005 |
Comparison of enzymatic properties between hPADI2 and hPADI4.
Topics: Amino Acid Sequence; Arginine; Arthritis, Rheumatoid; Calcium; Catalysis; Citrulline; Fibrinogen; Filaggrin Proteins; Humans; Hydrogen-Ion Concentration; Hydrolases; Immunohistochemistry; Intermediate Filament Proteins; Kinetics; Molecular Sequence Data; Protein Denaturation; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Substrate Specificity; Synovial Membrane | 2005 |
Arginine metabolism during macrophage autocrine activation and infection with mouse hepatitis virus 3.
Topics: Animals; Arginase; Arginine; Autocrine Communication; Bone Marrow Cells; Citrulline; Gene Expression; Immunity, Innate; Interferon-gamma; Interleukin-12; Interleukin-18; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Murine hepatitis virus; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Polyamines; Virus Replication | 2004 |
Supplemental enteral arginine is metabolized to ornithine in injured patients.
Topics: Adolescent; Adult; Aged; Arginase; Arginine; Citrulline; Energy Intake; Enteral Nutrition; Female; Humans; Infections; Male; Middle Aged; Ornithine; Wounds and Injuries | 2005 |
The soy isoflavone genistein induces a late but sustained activation of the endothelial nitric oxide-synthase system in vitro.
Topics: Arginine; Cell Line; Citrulline; Endothelial Cells; Enzyme Activation; Estradiol; Gene Expression Regulation, Enzymologic; Genes, Reporter; Genistein; Humans; Luciferases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phytoestrogens | 2005 |
Sunscreen ingredients inhibit inducible nitric oxide synthase (iNOS): a possible biochemical explanation for the sunscreen melanoma controversy.
Topics: Arginine; Citrulline; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Sunscreening Agents | 2005 |
Effect of arginine loss in myelin basic protein, as occurs in its deiminated charge isoform, on mediation of actin polymerization and actin binding to a lipid membrane in vitro.
Topics: Actin Cytoskeleton; Actins; Amino Acid Sequence; Animals; Arginine; Citrulline; Exons; Imines; Lipid Bilayers; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Myelin Basic Protein; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Isoforms; Recombinant Proteins; Static Electricity; Xenotropic and Polytropic Retrovirus Receptor | 2005 |
Interaction between ArgR and AhrC controls regulation of arginine metabolism in Lactococcus lactis.
Topics: Arginine; Bacterial Physiological Phenomena; Bacterial Proteins; Base Sequence; Catalysis; Citrulline; Deoxyribonuclease I; DNA; DNA Primers; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Deletion; Genome; Genome, Bacterial; Lactococcus lactis; Models, Biological; Models, Genetic; Molecular Sequence Data; Mutation; Plasmids; Point Mutation; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; RNA; Sequence Homology, Nucleic Acid; Trans-Activators; Transcription, Genetic; Transgenes | 2005 |
Brain neuronal nitric oxide synthase neuron-mediated sympathoinhibition is enhanced in hypertensive Dahl rats.
Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Hypertension; Immunohistochemistry; Injections, Intraventricular; Male; Medulla Oblongata; Nerve Tissue Proteins; Neural Inhibition; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pedunculopontine Tegmental Nucleus; Periaqueductal Gray; Raphe Nuclei; Rats; Rats, Inbred Dahl; Solitary Nucleus; Sympathetic Nervous System; Thiourea | 2005 |
Direct single cell determination of nitric oxide synthase related metabolites in identified nitrergic neurons.
Topics: Animals; Arginine; Argininosuccinic Acid; Cells, Cultured; Citrulline; Electric Conductivity; Electrophoresis, Capillary; Ganglia, Invertebrate; Intracellular Fluid; Lymnaea; Microscopy, Fluorescence; Nitrates; Nitrergic Neurons; Nitric Oxide Synthase; Nitrites; Ornithine | 2005 |
Humoral immune response to citrullinated collagen type II determinants in early rheumatoid arthritis.
Topics: Amino Acid Sequence; Animals; Antibody Formation; Arginine; Arthritis, Rheumatoid; Autoantibodies; Blotting, Western; Citrulline; Collagen Type II; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Epitopes, B-Lymphocyte; Female; Filaggrin Proteins; Humans; Hydrolases; Immunoglobulin G; Male; Mice; Middle Aged; Molecular Sequence Data; Protein-Arginine Deiminases; T-Lymphocytes | 2005 |
A designed synthetic analogue of 4-OT is specific for a non-natural substrate.
Topics: Amino Acid Substitution; Arginine; Binding Sites; Citrulline; Hydrogen Bonding; Isomerases; Kinetics; Static Electricity; Substrate Specificity; Urea | 2005 |
Lactobacillus plantarum ccl gene is non-essential, arginine-repressed and codes for a conserved protein in Firmicutes.
Topics: Arginine; Bacterial Proteins; Citrulline; Gene Deletion; Gene Expression Regulation, Bacterial; Genes, Bacterial; Lactobacillus plantarum; Promoter Regions, Genetic; Transcription, Genetic | 2005 |
Elevated plasma citrulline and arginine due to consumption of Citrullus vulgaris (watermelon).
Topics: Adult; Arginine; Citrulline; Citrullinemia; Citrullus; Developmental Disabilities; Diet; Female; Humans; Infant; Models, Biological; Nutritional Requirements; Urea | 2005 |
Intestinal renal metabolism of L-citrulline and L-arginine following enteral or parenteral infusion of L-alanyl-L-[2,15N]glutamine or L-[2,15N]glutamine in mice.
Topics: Algorithms; Animals; Arginine; Citrulline; Dipeptides; Glutamine; Hematocrit; Intestinal Mucosa; Intestines; Kidney; Kinetics; Male; Mice; p-Aminohippuric Acid; Regional Blood Flow; Renal Plasma Flow | 2005 |
Influence of ethanol and low pH on arginine and citrulline metabolism in lactic acid bacteria from wine.
Topics: Arginine; Citrulline; Ethanol; Hydrogen-Ion Concentration; Lactobacillaceae; Urethane; Wine | 2005 |
Functional characterization of brain mitochondrial nitric oxide synthase during hypertension and aging.
Topics: Aging; Animals; Arginine; Brain; Citrulline; Hypertension; Indazoles; Male; Mitochondria; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar | 2006 |
Methylation of the guanidino group of arginine residues prevents citrullination by peptidylarginine deiminase IV.
Topics: Arginine; Catalysis; Chromatography, High Pressure Liquid; Citrulline; Guanidine; Hydrolases; Methylation; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2005 |
Ornithine alpha-ketoglutarate metabolism in the healthy rat in the postabsorptive state.
Topics: Amino Acids, Branched-Chain; Animals; Arginine; Citrulline; Glutamic Acid; Intestinal Absorption; Intestinal Mucosa; Keto Acids; Ketoglutaric Acids; Liver; Male; Muscle, Skeletal; Ornithine; Proline; Rats; Rats, Wistar | 2005 |
Integrity and stability of the citrulline-arginine pathway in normal and tumour cell lines.
Topics: Animals; Arginine; Argininosuccinic Acid; Carbon Radioisotopes; Cell Division; Cells, Cultured; Citrulline; Cricetinae; Dogs; Humans; Mice; Neoplasms; Rats; Signal Transduction | 2005 |
The feeding route (enteral or parenteral) affects the plasma response of the dipetide Ala-Gln and the amino acids glutamine, citrulline and arginine, with the administration of Ala-Gln in preoperative patients.
Topics: Adult; Aged; Amino Acids; Analysis of Variance; Arginine; Citrulline; Dietary Supplements; Dipeptides; Enteral Nutrition; Female; Glutamic Acid; Glutamine; Humans; Male; Middle Aged; Parenteral Nutrition; Preoperative Care | 2005 |
Ornithine aminotransferase deficiency: diagnostic difficulties in neonatal presentation.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Citrulline; Diagnosis, Differential; Female; Fibroblasts; Glutamine; Humans; Hyperammonemia; Infant, Newborn; Male; Mutation; Neonatal Screening; Ornithine; Ornithine-Oxo-Acid Transaminase; Orotic Acid | 2005 |
l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.
Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Arteriosclerosis; Ascorbic Acid; Citrulline; Cyclic AMP Response Element-Binding Protein; Cyclic GMP; Diet, Atherogenic; DNA-Binding Proteins; Endothelium, Vascular; ets-Domain Protein Elk-1; Humans; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Proto-Oncogene Proteins; Rabbits; Superoxides; Transcription Factors; Vasodilation; Vitamin E | 2005 |
Vascular and renal effects of dopamine during extracellular volume expansion: Role of nitric oxide pathway.
Topics: Animals; Aorta; Arginine; Blood Pressure; Citrulline; Diuresis; Dopamine; Dopamine Antagonists; Extracellular Fluid; Haloperidol; Kidney; Male; NADPH Dehydrogenase; Natriuresis; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Renal Artery; Renal Plasma Flow | 2006 |
Metabolic fates of ammonia-N in ruminal epithelial and duodenal mucosal cells isolated from growing sheep.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Citrulline; Duodenum; Epithelium; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Intestinal Mucosa; Nitrogen; Nitrogen Isotopes; Rumen; Sheep; Urea | 2005 |
Increased nitric oxide (NO) pathway metabolites in the vitreous fluid of patients with rhegmatogenous retinal detachment or diabetic traction retinal detachment.
Topics: Aged; Arginine; Chromatography, High Pressure Liquid; Citrulline; Diabetic Retinopathy; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Retinal Detachment; Signal Transduction; Vitreous Body | 2006 |
Arginine metabolism, pulmonary hypertension, and sickle cell disease.
Topics: Anemia, Sickle Cell; Arginase; Arginine; Citrulline; Dietary Supplements; Humans; Hypertension, Pulmonary | 2005 |
Blood cell NO synthesis in response to exercise.
Topics: Adult; Arginase; Arginine; Bicycling; Citrulline; Erythrocytes; Exercise; Humans; Lymphocytes; Male; Neutrophils; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Ornithine; Superoxide Dismutase | 2006 |
Citrulline, Viagra and BiDil--bad medicine.
Topics: Adult; Arginine; Chronic Disease; Citrulline; Cyclic GMP; Endothelium, Vascular; Erectile Dysfunction; Humans; Hypertension, Pulmonary; Infant; Male; Marketing; Nitric Oxide; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasodilator Agents | 2005 |
Regulation of inducible nitric oxide synthase in post-operative adhesions.
Topics: Animals; Arginine; Biopsy; Biopterins; Citrulline; Female; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Nitric Oxide Synthase Type II; Oxygen; Rats; Rats, Sprague-Dawley; Tissue Adhesions | 2006 |
The regulatory PII protein controls arginine biosynthesis in Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Arginine; Carboxy-Lyases; Citrulline; Enzyme Activation; Gene Expression Profiling; Gene Expression Regulation, Plant; Mutation; Ornithine; Phosphotransferases (Alcohol Group Acceptor); PII Nitrogen Regulatory Proteins; Recombinant Proteins; RNA, Messenger; Transcription, Genetic | 2006 |
[Histone demethylation isn't what it used to be].
Topics: Arginine; Citrulline; Dioxygenases; F-Box Proteins; Gene Expression Regulation; Histone Demethylases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Hydrolases; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Oxidoreductases, N-Demethylating; Protein Methyltransferases; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases | 2006 |
HHH syndrome (hyperornithinaemia, hyperammonaemia, homocitrullinuria), with fulminant hepatitis-like presentation.
Topics: Alanine Transaminase; Amino Acid Transport Systems, Basic; Arginine; Aspartate Aminotransferases; Child, Preschool; Citrulline; Diet, Protein-Restricted; Hepatitis; Humans; Hyperammonemia; Liver; Male; Metabolism, Inborn Errors; Mitochondrial Membrane Transport Proteins; Ornithine; Proteins; Syndrome | 2006 |
Inhibition of protein synthesis by activation of NMDA receptors in cultured retinal cells: a new mechanism for the regulation of nitric oxide production.
Topics: Animals; Arginine; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chick Embryo; Citrulline; Elongation Factor 2 Kinase; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Nerve Tissue Proteins; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Peptide Elongation Factor 2; Phosphorylation; Protein Synthesis Inhibitors; Receptors, N-Methyl-D-Aspartate; Retina; Up-Regulation | 2006 |
Citrulline modulates muscle protein metabolism in old malnourished rats.
Topics: Age Factors; Amino Acids; Animals; Arginine; Citrulline; Creatine; Dietary Supplements; Duodenum; Food Deprivation; Insulin; Liver; Male; Malnutrition; Methylhistidines; Muscle Proteins; Muscle, Skeletal; Nitrogen; Ornithine; Proteins; Random Allocation; Rats; Rats, Sprague-Dawley | 2006 |
Quercetin inhibits eNOS, microtubule polymerization, and mitotic progression in bovine aortic endothelial cells.
Topics: Animals; Aorta; Arginine; Cattle; Cell Division; Cell Line; Citrulline; Endothelium, Vascular; Microtubules; Mitosis; Nitric Oxide Synthase Type III; Quercetin | 2006 |
Inhaled L-arginine improves exhaled nitric oxide and pulmonary function in patients with cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Adult; Arginine; Breath Tests; Citrulline; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Lung; Male; Middle Aged; Nitric Oxide; Ornithine; Pilot Projects; Respiratory System Agents | 2006 |
Infected chronic wounds show different local and systemic arginine conversion compared with acute wounds.
Topics: Acute Disease; Adult; Amino Acids; Arginase; Arginine; Body Fluids; Chronic Disease; Citrulline; Female; Humans; Male; Middle Aged; Nitrates; Nitrites; Ornithine; Prospective Studies; Wound Healing; Wound Infection; Wounds and Injuries | 2006 |
Route of administration (enteral or parenteral) affects the contribution of L-glutamine to de novo L-arginine synthesis in mice: a stable-isotope study.
Topics: Animals; Arginine; Citrulline; Enteral Nutrition; Glutamine; Male; Mice; Models, Biological; Nitrogen Isotopes; Parenteral Nutrition | 2006 |
Structure of the mammalian NOS regulator dimethylarginine dimethylaminohydrolase: A basis for the design of specific inhibitors.
Topics: Amidohydrolases; Amino Acid Sequence; Animals; Arginine; Brain; Cattle; Citrulline; Crystallography; Drug Design; Enzyme Inhibitors; Homocysteine; Isoenzymes; Molecular Sequence Data; Nitric Oxide Synthase; Protein Conformation; Zinc | 2006 |
Proteomics implicates peptidyl arginine deiminase 2 and optic nerve citrullination in glaucoma pathogenesis.
Topics: Aged; Aged, 80 and over; Animals; Arginine; Astrocytes; Blotting, Western; Citrulline; Disease Models, Animal; Down-Regulation; Female; Glaucoma, Open-Angle; Humans; Hydrolases; Immunohistochemistry; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Middle Aged; Optic Nerve Diseases; Proteomics; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2006 |
Phytoestrogen alpha-zearalanol antagonizes homocysteine-induced imbalance of nitric oxide/endothelin-1 and apoptosis in human umbilical vein endothelial cells.
Topics: Apoptosis; Arginine; bcl-2-Associated X Protein; Blotting, Western; Cells, Cultured; Citrulline; Endothelin-1; Endothelium, Vascular; Estradiol; Female; Gene Expression Regulation; Homocysteine; Humans; Nitric Oxide; Nitric Oxide Synthase; Phytoestrogens; Umbilical Veins; Zeranol | 2006 |
Citrulline is an effective arginine precursor in enterally fed neonatal piglets.
Topics: Amino Acids; Animals; Animals, Newborn; Arginine; Citrulline; Diet; Swine | 2006 |
Adverse effects of cigarette smoke on NO bioavailability: role of arginine metabolism and oxidative stress.
Topics: Adult; Animals; Antioxidants; Arginine; Biological Availability; Biological Transport; Cationic Amino Acid Transporter 1; Cattle; Cells, Cultured; Citrulline; Cotinine; Culture Media; Endothelial Cells; Enzyme Activation; Humans; Male; Nicotiana; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Oxidative Stress; Reactive Oxygen Species; Smoke; Smoking | 2006 |
Synthetic vascular prosthesis impregnated with mesenchymal stem cells overexpressing endothelial nitric oxide synthase.
Topics: Adenoviridae; Animals; Arginine; beta-Galactosidase; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Citrulline; DNA, Complementary; Equipment Design; Genes, Reporter; Genetic Vectors; Implants, Experimental; Lac Operon; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Polytetrafluoroethylene; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Transduction, Genetic | 2006 |
The uptake of glutamine and release of arginine, citrulline and proline by the small intestine of developing pigs.
Topics: Amino Acids; Animals; Arginine; Citrulline; Glutamine; Intestine, Small; Proline; Swine; Weaning | 1994 |
Impact of winemaking practices on arginine and citrulline metabolism during and after malolactic fermentation.
Topics: Arginine; Citrulline; Fermentation; Food Technology; Lactobacillaceae; Malates; Saccharomyces cerevisiae; Time Factors; Wine | 2006 |
Characterization of cationic amino acid transport systems in rat erythrocytes: lack of effect of uraemia on L-arginine influx.
Topics: Amino Acid Transport System y+; Amino Acid Transport System y+L; Animals; Arginine; Citrulline; Disease Models, Animal; Erythrocytes; Kinetics; Leucine; Lysine; Male; Nephrectomy; Ornithine; Rats; Rats, Wistar; Uremia | 2006 |
Role of the L-citrulline/L-arginine cycle in iNANC nerve-mediated nitric oxide production and airway smooth muscle relaxation in allergic asthma.
Topics: Allergens; Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Asthma; Citrulline; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth; N-Methylaspartate; Neural Inhibition; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Ovalbumin; Specific Pathogen-Free Organisms; Succinic Acid; Trachea | 2006 |
Effects of N-methyl-D-aspartate on extracellular citrulline level in the rat nucleus accumbens.
Topics: Animals; Arginine; Citrulline; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Male; Microdialysis; N-Methylaspartate; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 2006 |
Cardiac nitric oxide synthases are elevated in dietary copper deficiency.
Topics: Animals; Arginine; Citrulline; Copper; Diet; Male; Models, Animal; Myocardium; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley | 2007 |
Inhibitors and inactivators of protein arginine deiminase 4: functional and structural characterization.
Topics: Amidines; Arginine; Arthritis, Rheumatoid; Calcium; Chronic Disease; Citrulline; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrocarbons, Fluorinated; Hydrolases; Molecular Probes; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases | 2006 |
Understanding the enzymatic activity of 4-oxalocrotonate tautomerase and its mutant analogues: a computational study.
Topics: Arginine; Binding Sites; Citrulline; Computer Simulation; Databases, Protein; Dimerization; Enzymes; Hydrogen Bonding; Isomerases; Kinetics; Models, Chemical; Molecular Conformation; Mutation; Pseudomonas putida; Software | 2006 |
Nitric oxide and neopterin in bipolar affective disorder.
Topics: Adult; Arginine; Biopterins; Bipolar Disorder; Chi-Square Distribution; Citrulline; Female; Humans; Male; Mental Status Schedule; Middle Aged; Neopterin; Nitric Oxide | 2006 |
Degradation of arginine by Slackia exigua ATCC 700122 and Cryptobacterium curtum ATCC 700683.
Topics: Ammonia; Arginine; Chromatography, High Pressure Liquid; Citrulline; Dental Pulp Necrosis; Eubacterium; Humans; Hydrolases; Ornithine; Periodontal Pocket | 2006 |
Renal cell carcinoma does not express argininosuccinate synthetase and is highly sensitive to arginine deprivation via arginine deiminase.
Topics: Adult; Aged; Animals; Arginase; Arginine; Argininosuccinate Synthase; Carcinoma, Renal Cell; Cell Growth Processes; Citrulline; Female; Humans; Hydrolases; Kidney Neoplasms; Male; Mice; Mice, Inbred BALB C; Middle Aged; Neovascularization, Pathologic; Polyethylene Glycols; Survival Rate; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2007 |
Arginine, citrulline and nitrate concentrations in the cerebrospinal fluid from patients with acute hydrocephalus.
Topics: Adult; Albumins; Amino Acids; Arginine; Case-Control Studies; Citrulline; Humans; Hydrocephalus; Middle Aged; Nitrates | 2007 |
Arginine and urea metabolism in the liver graft: A study using microdialysis in human orthotopic liver transplantation.
Topics: Adolescent; Adult; Aged; Arginine; Brain Death; Cadaver; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Liver Transplantation; Microdialysis; Middle Aged; Ornithine; Tissue Donors; Urea | 2006 |
Does the ornithine-alpha-ketoglutarate ratio influence ornithine alpha-ketoglutarate metabolism in healthy rats?
Topics: Animals; Arginine; Citrulline; Glutamic Acid; Intestinal Mucosa; Ketoglutaric Acids; Liver; Male; Muscle, Skeletal; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Random Allocation; Rats; Rats, Wistar | 2007 |
Interorgan amino acid exchange in humans: consequences for arginine and citrulline metabolism.
Topics: Adult; Aged; Arginine; Blood Flow Velocity; Citrulline; Colorectal Neoplasms; Female; Glutamine; Hepatectomy; Humans; Intestine, Small; Kidney; Liver; Male; Middle Aged; Organ Specificity; Ornithine | 2007 |
Ubiquitous presence of argininosuccinate at millimolar levels in the central nervous system of Aplysia californica.
Topics: Animals; Aplysia; Arginine; Argininosuccinic Acid; Capillary Electrochromatography; Central Nervous System; Citrulline; Ganglia, Invertebrate; Hemolymph; In Vitro Techniques; Models, Biological; Nerve Net; Neurons | 2007 |
Conditional neuronal nitric oxide synthase overexpression impairs myocardial contractility.
Topics: Animals; Arginine; Caffeine; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cell Size; Cells, Cultured; Citrulline; Cyclic GMP; Doxycycline; Enzyme Induction; Ion Channel Gating; Mice; Mice, Transgenic; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide Synthase Type I; Ornithine; Protein Interaction Mapping; Recombinant Fusion Proteins; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stroke Volume; Ultrasonography; Ventricular Dysfunction, Left | 2007 |
Methylation of arginine residues interferes with citrullination by peptidylarginine deiminases in vitro.
Topics: Amino Acid Sequence; Animals; Arginine; Cells, Cultured; Citrulline; Histones; Humans; Hydrolases; Immunoenzyme Techniques; Methylation; Mice; Models, Biological; Molecular Sequence Data; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Protein-Arginine N-Methyltransferases; Sequence Homology, Amino Acid | 2007 |
Arginine deficiency in preconfluent intestinal Caco-2 cells modulates expression of proteins involved in proliferation, apoptosis, and heat shock response.
Topics: Apoptosis; Arginine; Caco-2 Cells; Cell Proliferation; Citrulline; Electrophoresis, Gel, Two-Dimensional; Heat-Shock Proteins; Humans; Proteome; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2007 |
Paracetamol inhibits nitric oxide synthesis in murine spinal cord slices.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arginine; Caffeine; Central Nervous System Stimulants; Cerebellum; Citrulline; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; In Vitro Techniques; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Spinal Cord | 2007 |
Intestinal and hepatic metabolism of glutamine and citrulline in humans.
Topics: Arginine; Biotransformation; Blood Flow Velocity; Carbon Isotopes; Citrulline; Glutamine; Hepatic Veins; Humans; Infusions, Intravenous; Intestinal Mucosa; Intestines; Laser-Doppler Flowmetry; Liver; Liver Circulation; Middle Aged; Nitrogen Isotopes; Portal Vein; Splanchnic Circulation | 2007 |
Activation of peroxynitrite by inducible nitric-oxide synthase: a direct source of nitrative stress.
Topics: Animals; Arginine; Carbon Dioxide; Chromatography, High Pressure Liquid; Citrulline; Fluorescence; Kinetics; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; Oxygen; Peroxynitrous Acid; Phenylacetates | 2007 |
Divergent polyamine metabolism in the Apicomplexa.
Topics: Animals; Apicomplexa; Arginine; Carbamyl Phosphate; Citrulline; Fibroblasts; Foreskin; Genome, Protozoan; Humans; Male; Ornithine; Polyamines; Putrescine; Spermidine; Toxoplasma | 2007 |
L-citrulline inhibits [3H]acetylcholine release from rat motor nerve terminals by increasing adenosine outflow and activation of A1 receptors.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Arginine; Citrulline; Dose-Response Relationship, Drug; Female; Male; Motor Neurons; Muscle Contraction; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar; Receptor, Adenosine A1 | 2007 |
Apoptotic cells induce arginase II in macrophages, thereby attenuating NO production.
Topics: Animals; Apoptosis; Arginase; Arginine; Blotting, Western; Cells, Cultured; Citrulline; Humans; Macrophage Activation; Macrophages; Mice; Necrosis; Nitric Oxide; Nitric Oxide Synthase Type II; Ornithine; RNA, Small Interfering | 2007 |
Effect of ocular hypertension on retinal nitridergic pathway activity.
Topics: Amino Acid Transport Systems, Basic; Animals; Anterior Chamber; Arginine; Blotting, Western; Citrulline; Cyclic GMP; Disease Models, Animal; Hyaluronic Acid; Intraocular Pressure; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ocular Hypertension; Radioimmunoassay; Rats; Rats, Wistar; Retina; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
Tumor necrosis factor-alpha reduces argininosuccinate synthase expression and nitric oxide production in aortic endothelial cells.
Topics: Animals; Aorta; Arginine; Argininosuccinate Synthase; Cattle; Cell Nucleus; Cells, Cultured; Citrulline; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Enzyme Repression; Genes, Reporter; Luciferases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type III; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Sp1 Transcription Factor; Sp3 Transcription Factor; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 2007 |
Protein arginine deiminase 4: evidence for a reverse protonation mechanism.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Citrulline; Cysteine; Histidine; Humans; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Protons; Recombinant Proteins; Substrate Specificity | 2007 |
Post-translational modifications in the rat lumbar spinal cord in experimental autoimmune encephalomyelitis.
Topics: Amino Acid Sequence; Animals; Arginine; Astrocytes; Citrulline; Encephalomyelitis, Autoimmune, Experimental; Glial Fibrillary Acidic Protein; Lumbar Vertebrae; Lysine; Methylation; Molecular Sequence Data; Multiple Sclerosis; Phosphorylation; Protein Processing, Post-Translational; Proteomics; Rats; Serine; Spinal Cord | 2007 |
Interference with the citrulline-based nitric oxide synthase assay by argininosuccinate lyase activity in Arabidopsis extracts.
Topics: Arabidopsis; Arabidopsis Proteins; Arginine; Argininosuccinate Lyase; Argininosuccinic Acid; Biological Assay; Catalysis; Chromatography, Ion Exchange; Chromatography, Thin Layer; Citrulline; Fumarates; Kinetics; Nitric Oxide Synthase; Plant Extracts | 2007 |
Determination of dimethylarginine dimethylaminohydrolase activity in the kidney.
Topics: Amidohydrolases; Animals; Arginine; Citrulline; Kidney; Male; Rats; Rats, Sprague-Dawley; Urea | 2007 |
[The effect of arginine and its metabolites on tissue culture of rat myocardium].
Topics: Amino Acids, Sulfur; Animals; Arginine; Cell Proliferation; Citrulline; Heart; Myocardium; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Ornithine; Rats; Tissue Culture Techniques; Urea | 2007 |
L-arginine is essential for conidiation in the filamentous fungus Coniothyrium minitans.
Topics: Arginine; Ascomycota; Blotting, Southern; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Citrulline; DNA, Bacterial; Fungal Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; RNA Interference; Signal Transduction; Spores, Fungal | 2007 |
Interaction between murine spf-ash mutation and genetic background yields different metabolic phenotypes.
Topics: Alanine; Ammonia; Animals; Arginine; Citrulline; Disease Models, Animal; Female; Glycine; Injections, Intravenous; Intestinal Mucosa; Liver; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Mice, Mutant Strains; Models, Biological; Mutation; Nitric Oxide; Ornithine; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Phenotype; Phenylalanine; Urea | 2007 |
Maternal supplementation with citrulline increases renal nitric oxide in young spontaneously hypertensive rats and has long-term antihypertensive effects.
Topics: Amino Acid Transport Systems, Basic; Amino Acids; Animals; Antihypertensive Agents; Arginine; Argininosuccinate Synthase; Blood Pressure; Citrulline; Female; Gene Expression Profiling; Kidney; Male; Maternal Nutritional Physiological Phenomena; Nitric Oxide; Nitric Oxide Synthase; Pregnancy; Rats; Rats, Inbred SHR | 2007 |
Reduced nitric oxide in diabetic kidneys due to increased hepatic arginine metabolism: implications for renomedullary oxygen availability.
Topics: alpha-Tocopherol; Animals; Antioxidants; Arginase; Arginine; Blood Pressure; Cationic Amino Acid Transporter 2; Cell Hypoxia; Citrulline; Diabetic Nephropathies; Glomerular Filtration Rate; Kidney Medulla; Liver; Male; Nitric Oxide; Ornithine; Oxidative Stress; Oxygen; Rats; Rats, Inbred WF; Regional Blood Flow | 2008 |
Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction.
Topics: Aged; Arginine; Biomarkers; Citrulline; Humans; Male; Methylation; Myocardial Infarction; Nitric Oxide; Ornithine; Oxidation-Reduction; Oxidative Stress; Predictive Value of Tests; Shock, Cardiogenic | 2007 |
[Effect of the arginine and its metabolites on the rat myocardium in organothypic tissue culture in young and old rats].
Topics: Animals; Arginine; Cell Proliferation; Citrulline; Heart; Liver; Lymphoid Tissue; Myocardium; Ornithine; Rats; Rats, Wistar; Tissue Culture Techniques; Urea | 2007 |
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Nitric Oxide Synthase; Nitrites; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2007 |
Plasma arginine and citrulline concentrations in critically ill children: strong relation with inflammation.
Topics: Amino Acids; Arginine; C-Reactive Protein; Child; Child, Preschool; Citrulline; Critical Illness; Female; Humans; Infant; Inflammation; Male | 2007 |
Dietary supplementation with watermelon pomace juice enhances arginine availability and ameliorates the metabolic syndrome in Zucker diabetic fatty rats.
Topics: Animals; Aorta; Arginine; Beverages; Blood Glucose; Citrulline; Citrullus; Diabetes Complications; Dietary Supplements; Drinking; Eating; Energy Metabolism; GTP Cyclohydrolase; Lipids; Metabolic Syndrome; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Zucker; Water | 2007 |
Biosynthesis of urea; enzymatic mechanism of arginine synthesis from citrulline.
Topics: Arginine; Citrulline; Urea | 1949 |
Biosynthesis of urea; arginine synthesis from citrulline in liver homogenates.
Topics: Arginine; Citrulline; Liver; Urea | 1949 |
Synthetic approaches to N(delta)-methylated L-arginine, N(omega)-hydroxy-L-arginine, L-citrulline, and N(delta)-cyano-L-ornithine.
Topics: Arginine; Boron Compounds; Citrulline; Molecular Structure; Ornithine; Oxazolone | 2008 |
Impairment of arginine metabolism in rats after massive intestinal resection: effect of parenteral nutrition supplemented with citrulline compared with arginine.
Topics: Animals; Arginine; Citrulline; Intestinal Mucosa; Intestine, Small; Male; Muscular Atrophy; Nitrogen; Parenteral Nutrition; Polyamines; Rats; Rats, Wistar; Short Bowel Syndrome; Weight Loss | 2008 |
Obesity reduces the bioavailability of nitric oxide in juveniles.
Topics: Adolescent; Arginine; Cardiovascular Diseases; Citrulline; Female; Humans; Insulin Resistance; Male; Nitric Oxide; Obesity | 2008 |
Myelin localization of peptidylarginine deiminases 2 and 4: comparison of PAD2 and PAD4 activities.
Topics: Animals; Arginine; Blotting, Western; Brain; Citrulline; Humans; Hydrolases; Immunohistochemistry; Mice; Mice, Knockout; Myelin Basic Protein; Myelin Sheath; Phosphatidylcholines; Phosphatidylserines; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases | 2008 |
iNOS activity in the aged rat liver tissue.
Topics: Aging; Animals; Arginine; Blotting, Western; Citrulline; Gene Expression; Immunohistochemistry; Kidney; Liver; Male; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
A density functional theory investigation on the mechanism of the second half-reaction of nitric oxide synthase.
Topics: Arginine; Binding Sites; Citrulline; Computer Simulation; Heme; Models, Chemical; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Oxygen; Quantum Theory | 2008 |
Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo.
Topics: Acetylcholine; Adult; Arginine; Brachial Artery; Citrulline; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Stress, Psychological; Thiourea; Vasodilation; Vasomotor System | 2008 |
Effect of chronic inhibition of converting enzyme on proximal tubule acidification.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Citrulline; Enalapril; Kidney Tubules, Proximal; Male; Nitric Oxide; Oxidation-Reduction; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Vacuolar Proton-Translocating ATPases | 2008 |
Postchemotherapy hyperammonemic encephalopathy emulating ornithine transcarbamoylase (OTC) deficiency.
Topics: Adult; Arginine; Carcinoma, Hepatocellular; Citrulline; Female; Glutamine; Hepatic Encephalopathy; Humans; Hyperammonemia; Liver Neoplasms; Ornithine; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Polymorphism, Single-Stranded Conformational; Syndrome | 2008 |
Measurement of NO and NO synthase.
Topics: Animals; Arginine; Citrulline; Colorimetry; Ethylenediamines; Luminescent Measurements; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Sulfanilamides | 2001 |
Arginine therapy of transgenic-knockout sickle mice improves microvascular function by reducing non-nitric oxide vasodilators, hemolysis, and oxidative stress.
Topics: Acetylcholine; Anemia, Sickle Cell; Animals; Arginine; Citrulline; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Enzyme Inhibitors; Globins; Heme Oxygenase-1; Hemodynamics; Hemoglobins; Hemolysis; Humans; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; Oxidative Stress; Tyrosine; Vasodilator Agents | 2008 |
Glutamine is an important precursor for de novo synthesis of arginine in humans.
Topics: Analysis of Variance; Arginine; Carbon Isotopes; Citrulline; Deuterium; Digestive System Surgical Procedures; Female; Glutamine; Humans; Infusions, Intravenous; Kidney; Liver; Male; Middle Aged; Nitrogen Isotopes; Pancreas | 2008 |
The 2007 ESPEN Sir David Cuthbertson Lecture: amino acids between and within organs. The glutamate-glutamine-citrulline-arginine pathway.
Topics: Amino Acids; Arginine; Citrulline; Critical Illness; Enteral Nutrition; Glutamic Acid; Glutamine; Humans; Kidney; Liver; Organ Specificity; Parenteral Nutrition | 2008 |
L-arginine plasma levels and severity of idiopathic pulmonary arterial hypertension.
Topics: Adult; Aged; Arginine; Biomarkers; Blood Pressure; Cardiac Catheterization; Chromatography, High Pressure Liquid; Citrulline; Cohort Studies; Exercise Test; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Middle Aged; Pilot Projects; Pulmonary Artery; Severity of Illness Index | 2008 |
Dietary supplementation with cholesterol and docosahexaenoic acid increases the activity of the arginine-nitric oxide pathway in tissues of young pigs.
Topics: Analysis of Variance; Animals; Animals, Newborn; Arginine; Biopterins; Blotting, Western; Brain; Cholesterol, Dietary; Chromatography, High Pressure Liquid; Citrulline; Dietary Supplements; Docosahexaenoic Acids; GTP Cyclohydrolase; Liver; Muscle, Skeletal; NADP; Nitric Oxide; Nitric Oxide Synthase; Swine | 2008 |
Interorgan synthesis of arginine is down-regulated in tumor-bearing mice undergoing surgical trauma.
Topics: Amino Acids; Animals; Arginine; Cell Line, Tumor; Citrulline; Down-Regulation; Glutamine; Laparotomy; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Postoperative Complications; Regional Blood Flow; Sarcoma, Experimental; Tissue Distribution | 2008 |
Increase in brain tumor permeability in glioma-bearing rats with nitric oxide donors.
Topics: Administration, Oral; Animals; Arginine; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Citrulline; Cyclic GMP; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Synergism; Female; Glioma; Hydroxyurea; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Rats; Rats, Inbred F344; Tumor Cells, Cultured | 2008 |
Citrullinated fibrinogen inhibits thrombin-catalysed fibrin polymerization.
Topics: Arginine; Blood Coagulation; Catalysis; Citrulline; Edetic Acid; Fibrin; Fibrinogen; Humans; Inflammation; Kinetics; Peptides; Substrate Specificity; Thrombin; Time Factors | 2008 |
A new severe acute necrotizing pancreatitis model induced by L-ornithine in rats.
Topics: alpha-Amylases; Animals; Apoptosis; Arginine; Citrulline; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Ornithine; Pancreatic alpha-Amylases; Pancreatitis, Acute Necrotizing; Peroxidase; Rats; Rats, Wistar; Time Factors; Trypsin | 2008 |
Lateralization of hippocampal nitric oxide mediator system in people with Alzheimer disease, multi-infarct dementia and schizophrenia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Citrulline; Dementia, Multi-Infarct; Female; Functional Laterality; Glutamine; Hippocampus; Humans; Isoenzymes; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Schizophrenia; Signal Transduction | 2008 |
Reduced citrulline availability by OTC deficiency in mice is related to reduced nitric oxide production.
Topics: Animals; Arginine; Biological Availability; Carbon Isotopes; Citrulline; Deuterium; Female; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Nitric Oxide; Nitrogen Isotopes; Ornithine Carbamoyltransferase Deficiency Disease | 2008 |
Possible indirect detection of rHuEPO administration in human urine by high-performance liquid chromatography tandem mass spectrometry.
Topics: Adult; Amidohydrolases; Arginine; Biomarkers; Chromatography, High Pressure Liquid; Citrulline; Doping in Sports; Erythropoietin; Humans; Injections, Intravenous; Male; Nitric Oxide Synthase; Predictive Value of Tests; Recombinant Proteins; Reference Values; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry | 2008 |
Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation.
Topics: Animals; Arginine; Autoimmune Diseases; Citrulline; Cornea; Glycosylation; Humans; Hydrolases; Inflammation; Interleukin-8; Neovascularization, Physiologic; Phosphorylation; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Rabbits | 2008 |
Letter by Stuehlinger et al regarding article, "Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction".
Topics: Aged; Arginine; Biomarkers; Citrulline; Hemodynamics; Humans; Male; Methylation; Myocardial Infarction; Nitric Oxide; Ornithine; Oxidation-Reduction; Oxidative Stress; Predictive Value of Tests; Shock, Cardiogenic | 2008 |
Co-administration of nitric oxide (NO) donors prevents haloperidol-induced orofacial dyskinesia, oxidative damage and change in striatal dopamine levels.
Topics: Animals; Antipsychotic Agents; Arginine; Chromatography, High Pressure Liquid; Citrulline; Dopamine; Dyskinesia, Drug-Induced; Haloperidol; Male; Molsidomine; Movement Disorders; Neostriatum; Nitric Oxide Donors; Oxidative Stress; Rats; Rats, Wistar; Superoxides | 2009 |
Mechanisms and kinetics of citrulline uptake in a model of human intestinal epithelial cells.
Topics: Arginine; Caco-2 Cells; Carbon Radioisotopes; Carrier Proteins; Citrulline; Electric Impedance; Humans; Intestinal Absorption; Intestine, Small | 2008 |
Nitric oxide production and monoamine oxidase activity in cancer patients during interferon-alpha therapy.
Topics: Adult; Aged; Arginine; Blood Platelets; Carcinoma, Renal Cell; Citrulline; Female; Humans; Interferon-alpha; Kidney Neoplasms; Male; Melanoma; Middle Aged; Monoamine Oxidase; Nitrates; Nitric Oxide; Nitrites; Prospective Studies; Skin Neoplasms | 2009 |
Arginine and citrulline do not stimulate growth of two Oenococcus oeni strains in wine.
Topics: Arginine; Citrulline; Food Technology; Gram-Positive Cocci; Lactobacillus; Wine | 2009 |
Primary sequence, together with other factors, influence peptide deimination by peptidylarginine deiminase-4.
Topics: Amino Acid Sequence; Arginine; Citrulline; Cyclization; Humans; Hydrolases; Kinetics; Molecular Sequence Data; Peptides; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2009 |
Reduced citrulline production in sepsis is related to diminished de novo arginine and nitric oxide production.
Topics: Arginine; Carbon Isotopes; Case-Control Studies; Citrulline; Critical Illness; Deuterium; Female; Humans; Infusions, Intravenous; Intensive Care Units; Isotope Labeling; Male; Middle Aged; Nitric Oxide; Nitrogen Isotopes; Nutritional Requirements; Shock, Septic | 2009 |
Arginine, citrulline and nitric oxide metabolism in sepsis.
Topics: Arginine; Case-Control Studies; Citrulline; Female; Homeostasis; Humans; Leucine; Male; Middle Aged; Nitric Oxide; Shock, Septic | 2009 |
Reengineering of a Corynebacterium glutamicum L-arginine and L-citrulline producer.
Topics: Arginine; Citrulline; Corynebacterium glutamicum; Escherichia coli Proteins; Gene Deletion; Genes, Bacterial; Metabolic Networks and Pathways; Mutation; Recombination, Genetic | 2009 |
Memory-related changes in L-citrulline and agmatine in the rat brain.
Topics: Agmatine; Animals; Arginine; Brain; Citrulline; Male; Maze Learning; Memory; Ornithine; Random Allocation; Rats; Rats, Sprague-Dawley | 2009 |
Effect of uncoupling endothelial nitric oxide synthase on calcium homeostasis in aged porcine endothelial cells.
Topics: Animals; Arginine; Biopterins; Bradykinin; Calcium; Cells, Cultured; Cellular Senescence; Citrulline; Cyclic GMP; Endothelial Cells; Enzyme Inhibitors; Homeostasis; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Superoxides; Swine; Time Factors | 2009 |
Hematologic, biochemical, and cardiopulmonary effects of L-arginine supplementation or phosphodiesterase 5 inhibition in patients with sickle cell disease who are on hydroxyurea therapy.
Topics: Adult; Anemia, Sickle Cell; Arginase; Arginine; beta-Globins; Citrulline; Cyclic Nucleotide Phosphodiesterases, Type 5; Female; Fetal Hemoglobin; Humans; Hydroxyurea; Male; Middle Aged; Ornithine; Phosphodiesterase Inhibitors; Piperazines; Purines; Reticulocyte Count; Sildenafil Citrate; Sulfones | 2009 |
Evaluation of endogenous nitric oxide synthesis in congenital urea cycle enzyme defects.
Topics: Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Child, Preschool; Citrulline; Female; Humans; Infant; Infant, Newborn; Male; Nitric Oxide; Nitric Oxide Synthase; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Urea | 2009 |
Plasma asymmetric dimethylarginine is related to anticitrullinated protein antibodies in rheumatoid arthritis of short duration.
Topics: Antibodies; Arginine; Arthritis, Rheumatoid; Blood Proteins; Citrulline; Humans; Nitric Oxide; Time Factors | 2009 |
Intravenous administration of L-citrulline to pregnant ewes is more effective than L-arginine for increasing arginine availability in the fetus.
Topics: Animals; Arginine; Citrulline; Female; Fetus; Injections, Intravenous; Mothers; Pregnancy; Sheep | 2009 |
Selective neuronal nitric oxide synthase inhibitors and the prevention of cerebral palsy.
Topics: Animals; Animals, Newborn; Arginine; Behavior, Animal; Blood Pressure; Brain; Cerebral Palsy; Citrulline; Crystallography, X-Ray; Disease Models, Animal; Drug Design; Enzyme Inhibitors; Female; Male; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Pregnancy; Rabbits; Structure-Activity Relationship | 2009 |
Altered arginine metabolism in the central nervous system (CNS) of the Cln3-/- mouse model of juvenile Batten disease.
Topics: Animals; Arginine; Brain; Cationic Amino Acid Transporter 1; Cells, Cultured; Citrulline; Disease Models, Animal; Female; Gene Expression; Liver; Male; Membrane Glycoproteins; Mice; Mice, Knockout; Molecular Chaperones; Neuronal Ceroid-Lipofuscinoses; Neurons; Nitric Oxide; Nitric Oxide Synthase; Protein Isoforms; RNA, Messenger; Urea | 2009 |
Effect of enzymatic deimination on the conformation of recombinant prion protein.
Topics: Anilino Naphthalenesulfonates; Animals; Arginine; Birefringence; Circular Dichroism; Citrulline; Electrophoresis, Polyacrylamide Gel; Endopeptidase K; Fluorescent Dyes; Prions; Protein Conformation; Protein Processing, Post-Translational; Recombinant Proteins; Sheep; Spectroscopy, Fourier Transform Infrared | 2009 |
Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death.
Topics: Anemia, Sickle Cell; Arginine; Case-Control Studies; Citrulline; Follow-Up Studies; Hemolysis; Humans; Hypertension, Pulmonary; Kidney Diseases; Linear Models; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Proportional Hazards Models; Risk; Survival Rate | 2009 |
Muscarinic receptor-mediated nitric oxide release in a K562 erythroleukaemia cell line.
Topics: Arginine; Carbachol; Chromatography, High Pressure Liquid; Citrulline; Dose-Response Relationship, Drug; Humans; K562 Cells; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Nitric Oxide; Nitric Oxide Synthase; Piperidines; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tropicamide | 2009 |
Absence of nitric-oxide synthase in sequentially purified rat liver mitochondria.
Topics: Animals; Arginine; Blotting, Western; Calmodulin; Citrulline; Immunochemistry; Isoenzymes; Male; Mass Spectrometry; Mitochondria, Liver; NADP; Nitric Oxide Synthase; Proteome; Rats; Rats, Sprague-Dawley | 2009 |
Plasma levels of nitric oxide related amino acids in demented subjects with Down syndrome are related to neopterin concentrations.
Topics: Alzheimer Disease; Amino Acids; Amino Acids, Aromatic; Amino Acids, Branched-Chain; Arginine; Citrulline; Cohort Studies; Dementia; Depression; Down Syndrome; Epilepsy; Female; Humans; Intellectual Disability; Male; Middle Aged; Neopterin; Nitric Oxide; Oxidative Stress; Severity of Illness Index | 2010 |
Enteral administration of alanyl-[2-(15)N]glutamine contributes more to the de novo synthesis of arginine than does intravenous infusion of the dipeptide in humans.
Topics: Arginine; Body Mass Index; Citrulline; Dipeptides; Enteral Nutrition; Female; Gastrointestinal Diseases; Glutamine; Humans; Infusions, Intravenous; Isotope Labeling; Male; Middle Aged; Neoplasms; Nitrogen Isotopes | 2009 |
Diminished global arginine bioavailability and increased arginine catabolism as metabolic profile of increased cardiovascular risk.
Topics: Aged; Arginine; Biological Availability; C-Reactive Protein; Citrulline; Confidence Intervals; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Odds Ratio; Ornithine; Prognosis; Prospective Studies; Risk Assessment; Risk Factors | 2009 |
Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition.
Topics: Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Citrulline; Coronary Artery Disease; Creatinine; Female; Humans; Lysine; Male; Metabolomics; Methylation; Middle Aged; Nitric Oxide Synthase; Odds Ratio; omega-N-Methylarginine; Ornithine; Prognosis; Prospective Studies; Protein Processing, Post-Translational; Risk Assessment; Risk Factors; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors | 2009 |
Differential regulation of neuronal and inducible nitric oxide synthase (NOS) in the spinal cord of mutant SOD1 (G93A) ALS mice.
Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; Citrulline; Mice; Mice, Transgenic; Motor Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Spinal Cord; Superoxide Dismutase | 2009 |
Rhodotorula arctica sp. nov., a basidiomycetous yeast from Arctic soil.
Topics: Arctic Regions; Arginine; Citrulline; Culture Media; DNA, Fungal; DNA, Ribosomal; DNA, Ribosomal Spacer; Genotype; Molecular Sequence Data; Mycological Typing Techniques; Phenotype; Phylogeny; Rhodotorula; Sequence Analysis, DNA; Soil Microbiology; Species Specificity; Thiamine | 2010 |
Ask the doctor. My husband is taking arginine and citrulline supplements because he read that they will protect his heart and arteries. Should I try these supplements, too, or is this a waste of money?
Topics: Amino Acids; Arginine; Cardiovascular Diseases; Cardiovascular System; Citrulline; Coronary Vessels; Humans; Nitric Oxide | 2009 |
Effect of peroxynitrite on endothelial L-arginine transport and metabolism.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Citrulline; Endothelium, Vascular; Nitric Oxide; Nitrosation; Oxidative Stress; Peroxynitrous Acid; Protein Transport; TRPV Cation Channels | 2009 |
Age-related changes in arginine and its metabolites in memory-associated brain structures.
Topics: Aging; Analysis of Variance; Animals; Arginase; Arginine; Brain; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memory; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley | 2009 |
Environmental pH determines citrulline and ornithine release through the arginine deiminase pathway in Lactobacillus fermentum IMDO 130101.
Topics: Antiporters; Arginine; Bacterial Proteins; Citrulline; Fermentation; Genes, Bacterial; Hydrogen-Ion Concentration; Hydrolases; Limosilactobacillus fermentum; Metabolic Networks and Pathways; Models, Biological; Operon; Ornithine; Ornithine Carbamoyltransferase; Phosphotransferases (Carboxyl Group Acceptor) | 2009 |
The arginine deiminase pathway of Lactobacillus fermentum IMDO 130101 responds to growth under stress conditions of both temperature and salt.
Topics: Arginine; Bread; Citrulline; Hydrolases; Kinetics; Limosilactobacillus fermentum; Models, Theoretical; Ornithine; Osmolar Concentration; Sodium Chloride; Stress, Physiological; Temperature | 2009 |
EPR and ENDOR characterization of the reactive intermediates in the generation of NO by cryoreduced oxy-nitric oxide synthase from Geobacillus stearothermophilus.
Topics: Arginine; Bacterial Proteins; Catalytic Domain; Citrulline; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Geobacillus stearothermophilus; Heme; Models, Molecular; Nitric Oxide; Nitric Oxide Synthase; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction | 2009 |
Adverse effects associated with arginine alpha-ketoglutarate containing supplements.
Topics: Adult; Arginine; Arrhythmias, Cardiac; Blood Pressure; Citrulline; Dietary Supplements; Dizziness; Electrocardiography; Heart Rate; Humans; Ketoglutaric Acids; Male; Methemoglobin; Nitric Oxide; Young Adult | 2009 |
Role of dimethylarginine dimethylaminohydrolases in the regulation of endothelial nitric oxide production.
Topics: Amidohydrolases; Animals; Arginine; Cattle; Citrulline; Endothelium, Vascular; Gene Expression; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase Type III | 2009 |
Effect of citrullination on the function and conformation of antithrombin.
Topics: Antithrombins; Arginine; Citrulline; Electrophoresis, Polyacrylamide Gel; Humans; Hydrolases; Models, Molecular; Protein Multimerization; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein-Arginine Deiminases; Structure-Activity Relationship | 2009 |
In vivo renal arginine release is impaired throughout development of chronic kidney disease.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Chronic Disease; Citrulline; Disease Models, Animal; Kidney Cortex; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 2010 |
Role of arginine guanidinium moiety in nitric-oxide synthase mechanism of oxygen activation.
Topics: Animals; Arginine; Binding Sites; Catalytic Domain; Citrulline; Enzyme Activation; Guanidine; Heme; Hydrogen Bonding; Mice; Models, Molecular; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxygen; Reactive Nitrogen Species; Reactive Oxygen Species; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2010 |
Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production.
Topics: Adenoviridae; Animals; Arginine; Atherosclerosis; Chlorocebus aethiops; Citrulline; COS Cells; Diabetes Mellitus; Endothelial Cells; Gene Expression; Heart Failure; Humans; Hydrolysis; Hypertension; Kidney; Liver; Mice; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; Transaminases; Transduction, Genetic | 2010 |
Metabotropic glutamate receptor 5, but not 1, modulates NMDA receptor-mediated activation of neuronal nitric oxide synthase.
Topics: Animals; Arginine; Blotting, Western; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic AMP; Cyclic GMP; Enzyme Activation; Excitatory Amino Acid Agonists; Guanylate Cyclase; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Oncogene Protein v-akt; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2010 |
Potential utility of full-spectrum antioxidant therapy, citrulline, and dietary nitrate in the management of sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Antioxidants; Arginine; Citrulline; Hemoglobins; Humans; Models, Biological; Nitrates; Nitric Oxide; Oxidative Stress; Vegetables | 2010 |
Nitric oxide and endothelin after lipid apheresis - a pilot study.
Topics: Adult; Aged; Analysis of Variance; Arginine; Atherosclerosis; Biomarkers; Blood Component Removal; Case-Control Studies; Citrulline; Endothelin-1; Female; Humans; Hyperlipoproteinemia Type II; Lipids; Male; Middle Aged; Nitric Oxide; Pilot Projects; Treatment Outcome | 2009 |
'Relaxers' damage hair: evidence from amino acid analysis.
Topics: Adolescent; Adult; Amino Acids; Arginine; Black People; Citrulline; Cystine; Female; Glutamine; Hair; Hair Preparations; Humans; Trichothiodystrophy Syndromes | 2010 |
Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression.
Topics: Arginine; Cell Line, Tumor; Citrulline; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, p53; Histone Deacetylase 2; Histones; Humans; Hydrolases; Lysine; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Tumor Suppressor Protein p53 | 2010 |
Long-term outcome of patients with argininosuccinate lyase deficiency diagnosed by newborn screening in Austria.
Topics: Adolescent; Adult; Arginine; Argininosuccinic Aciduria; Austria; Child; Child, Preschool; Citrulline; Electroencephalography; Female; Follow-Up Studies; Humans; Infant, Newborn; Male; Neonatal Screening; Treatment Outcome | 2010 |
Research on the reaction of Borsook and Dubnoff (synthesis of arginine from citrulline in the presence of glutamic acid).
Topics: Arginine; Citrulline; Thiamine | 1947 |
The conversion of citrulline to arginine (transimination) by tissue slices and homogenates.
Topics: Arginine; Citrulline; Humans; Tissues | 1946 |
Dysregulation of L-arginine metabolism and bioavailability associated to free plasma heme.
Topics: Amino Acid Transport System y+; Amino Acid Transport System y+L; Arginase; Arginine; Biological Availability; Biological Transport; Cells, Cultured; Citrulline; Endothelial Cells; Enzyme Activation; Erythrocytes; Hemin; Humans; Hydrolysis; Kinetics; Malaria, Falciparum; Microvessels; Nitric Oxide; Nitric Oxide Synthase Type III; Ornithine; Urea | 2010 |
Effects of maternal L-citrulline supplementation on renal function and blood pressure in offspring exposed to maternal caloric restriction: the impact of nitric oxide pathway.
Topics: Analysis of Variance; Animals; Animals, Newborn; Arginine; Blood Pressure; Blotting, Western; Body Weight; Caloric Restriction; Citrulline; Female; Histocytochemistry; Kidney; Kidney Cortex; Kidney Glomerulus; Male; Maternal Exposure; Nephrons; Nitric Oxide; Pregnancy; Rats; Signal Transduction | 2010 |
Glutamine: precursor or nitrogen donor for citrulline synthesis?
Topics: Ammonia; Animals; Arginine; Carbon Isotopes; Citrulline; Gastrointestinal Tract; Glutamine; Male; Mass Spectrometry; Mice; Mice, Inbred ICR; Nitrogen; Nitrogen Isotopes; Proline; Random Allocation; Specific Pathogen-Free Organisms | 2010 |
Effects of angiotensin type 1 receptor blockade on arginine and ADMA synthesis and metabolic pathways in fawn-hooded hypertensive rats.
Topics: Amidohydrolases; Angiotensin II Type 1 Receptor Blockers; Animals; Arginine; Biphenyl Compounds; Citrulline; Hypertension; Irbesartan; Male; Metabolic Networks and Pathways; Nitric Oxide; Rats; Tetrazoles | 2010 |
Simultaneous determination of l-citrulline and l-arginine in plasma by high performance liquid chromatography.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Case-Control Studies; Chromatography, High Pressure Liquid; Citrulline; Female; Humans; Indicators and Reagents; Limit of Detection; Male; Methods; Middle Aged; Neoplasms | 2010 |
Plasma arginine and ornithine are the main citrulline precursors in mice infused with arginine-free diets.
Topics: Animals; Arginine; Citrulline; Diet; Glutamine; Male; Mice; Ornithine; Phenylalanine; Proline | 2010 |
Artifacts related to N-methyl-N-(tert-butyldimethylsilyl)trifluoroacetamide derivatization of citrulline revealed by gas chromatography-mass spectrometry using both electron and chemical ionization.
Topics: Acetamides; Arginine; Artifacts; Citrulline; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Organosilicon Compounds; Ornithine; Temperature; Trifluoroacetic Acid | 2010 |
Cancer cell sensitivity to arginine deprivation in vitro is not determined by endogenous levels of arginine metabolic enzymes.
Topics: Arginase; Arginine; Argininosuccinate Synthase; Citrulline; Epithelial Cells; Humans; Neoplasms; Ornithine; Ornithine Carbamoyltransferase; Tumor Cells, Cultured | 2010 |
Inhibition of arginase activity ameliorates L-arginine-induced acute pancreatitis in rats.
Topics: Acute Disease; Aminocaproates; Aminocaproic Acid; Animals; Arginase; Arginine; Cattle; Citrulline; Glutathione Peroxidase; Heat-Shock Proteins; Male; Ornithine; Pancreas; Pancreatitis; Peroxidase; Rats; Rats, Wistar; Severity of Illness Index | 2010 |
In vitro and in vivo induction and activation of nNOS by LPS in oligodendrocytes.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Analysis of Variance; Animals; Animals, Newborn; Arginine; Basic Helix-Loop-Helix Transcription Factors; Brain; Cell Survival; Cells, Cultured; Citrulline; Corpus Callosum; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Indazoles; Lipopolysaccharides; Nerve Tissue Proteins; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; O Antigens; Oligodendroglia; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Stem Cells; Tritium | 2010 |
L-citrulline attenuates arrested alveolar growth and pulmonary hypertension in oxygen-induced lung injury in newborn rats.
Topics: Animals; Animals, Newborn; Arginine; Bronchopulmonary Dysplasia; Citrulline; Disease Models, Animal; Humans; Hypertension, Pulmonary; Infant, Newborn; Lung; Lung Injury; Nitric Oxide; Pulmonary Alveoli; Rats | 2010 |
Simultaneous quantitative determination of N(G),N(G)-dimethyl-L-arginine or asymmetric dimethylarginine and related pathway's metabolites in biological fluids by ultrahigh-performance liquid chromatography/electrospray ionization-tandem mass spectrometry.
Topics: Adult; Arginine; Body Fluids; Chromatography, High Pressure Liquid; Citrulline; Enzyme Inhibitors; Humans; Infant, Newborn; Middle Aged; Nitric Oxide; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2010 |
Arginine is synthesized from proline, not glutamate, in enterally fed human preterm neonates.
Topics: Arginine; Chromatography, Liquid; Citrulline; Enteral Nutrition; Glutamic Acid; Humans; Infant, Newborn; Infant, Premature; Isotope Labeling; Ornithine; Proline; Tandem Mass Spectrometry | 2011 |
Enhancement of the citrulline-nitric oxide cycle in astroglioma cells by the proline-rich peptide-10c from Bothrops jararaca venom.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Astrocytoma; Brain Neoplasms; Cell Division; Cell Line, Tumor; Citrulline; Crotalid Venoms; Dose-Response Relationship, Drug; Drug Design; Neuroglia; Nitric Oxide; Proline-Rich Protein Domains; Rats; Up-Regulation | 2010 |
Reduced expression of intestinal N-acetylglutamate synthase in suckling piglets: a novel molecular mechanism for arginine as a nutritionally essential amino acid for neonates.
Topics: Amino-Acid N-Acetyltransferase; Animals; Animals, Newborn; Animals, Suckling; Arginine; Citrulline; Down-Regulation; Female; Intestine, Small; Male; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine | 2011 |
Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Blotting, Western; Body Weight; Citrulline; Histocytochemistry; Hypertension; Male; Melatonin; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Organ Size; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2010 |
Enteral arginase II provides ornithine for citrulline synthesis.
Topics: Animals; Arginase; Arginine; Carbon Isotopes; Citrulline; Glutamine; Intestinal Mucosa; Intestine, Small; Kidney; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrogen Isotopes; Ornithine; Phenylalanine; Proline; Random Allocation | 2011 |
Re and Tc tricarbonyl complexes: from the suppression of NO biosynthesis in macrophages to in vivo targeting of inducible nitric oxide synthase.
Topics: Animals; Arginine; Cell Line, Tumor; Cell Membrane Permeability; Citrulline; Coordination Complexes; Enzyme Inhibitors; Female; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Molecular Probes; Nitric Oxide; Nitric Oxide Synthase Type II; Organ Specificity; Rhenium; Technetium; Tissue Distribution | 2010 |
Acute endotoxemia following transjugular intrahepatic stent-shunt insertion is associated with systemic and cerebral vasodilatation with increased whole body nitric oxide production in critically ill cirrhotic patients.
Topics: Acute Disease; Ammonia; Arginine; Cerebrovascular Circulation; Citrulline; Critical Illness; Cytokines; Endotoxemia; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Neutrophils; Nitric Oxide; Portasystemic Shunt, Transjugular Intrahepatic; Vasodilation | 2011 |
Nitric oxide synthase inhibitors and cerebral vasospasm.
Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; S-Adenosylmethionine; Vasospasm, Intracranial | 2011 |
Arginase activities and global arginine bioavailability in wild-type and ApoE-deficient mice: responses to high fat and high cholesterol diets.
Topics: Alanine Transaminase; Animal Feed; Animals; Apolipoproteins E; Arginase; Arginine; Biological Availability; Cholesterol; Citrulline; Diet; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Ornithine; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
The complete microspeciation of arginine and citrulline.
Topics: Arginine; Chemistry, Pharmaceutical; Citrulline; Hydrogen-Ion Concentration; Isoelectric Point; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Potentiometry; Protons | 2011 |
Quantification of arginine and its metabolites in human erythrocytes using liquid chromatography-tandem mass spectrometry.
Topics: Arginine; Chromatography, High Pressure Liquid; Citrulline; Erythrocytes; Humans; Nitric Oxide; Ornithine; Tandem Mass Spectrometry | 2011 |
Analysis of ven3 and ven6 reticulate mutants reveals the importance of arginine biosynthesis in Arabidopsis leaf development.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Arabidopsis; Arabidopsis Proteins; Arginine; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Citrulline; Escherichia coli; Ethyl Methanesulfonate; Mesophyll Cells; Metabolomics; Molecular Sequence Data; Morphogenesis; Mutation; Ornithine; Phenotype; Plant Leaves; Sequence Alignment | 2011 |
Simultaneous bioanalysis of L-arginine, L-citrulline, and dimethylarginines by LC-MS/MS.
Topics: Animals; Arginine; Cell Line; Chromatography, Liquid; Citrulline; Drug Stability; Extracellular Space; Humans; Male; Nitrogen Isotopes; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2011 |
The kinetics of the arginine deiminase pathway in the meat starter culture Lactobacillus sakei CTC 494 are pH-dependent.
Topics: Arginine; Citrulline; Fermentation; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Lactobacillus; Meat Products; Metabolic Networks and Pathways; Ornithine | 2011 |
Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Apoptosis; Arginine; Citrulline; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastrointestinal Agents; HT29 Cells; Humans; Hydrolases; Mice; Mice, Inbred C57BL; Ornithine; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Up-Regulation | 2011 |
Dose effects of chronically infused nitric oxide synthase inhibitor N(G)-nitro-L-arginine methyl ester on anabolic response and arginine metabolism in rats with subacute peritonitis.
Topics: Acute Disease; Amino Acids; Animals; Arginine; Citrulline; Deficiency Diseases; Enzyme Inhibitors; Inflammation; Leukocytes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrogen; Parenteral Nutrition Solutions; Parenteral Nutrition, Total; Peritonitis; Rats; Rats, Wistar; Serum Albumin; Weight Gain | 2011 |
RNA interference of argininosuccinate synthetase restores sensitivity to recombinant arginine deiminase (rADI) in resistant cancer cells.
Topics: Antineoplastic Agents; Arginine; Argininosuccinate Synthase; Cell Line, Tumor; Cell Survival; Citrulline; Drug Resistance, Neoplasm; Gene Expression; HeLa Cells; Humans; Hydrolases; Neoplasms; Recombinant Proteins; RNA Interference; RNA, Small Interfering | 2011 |
Glutamine, ornithine, citrulline and arginine levels in children with phenylketonuria: The diet effect.
Topics: Arginine; Case-Control Studies; Child; Citrulline; Diet; Female; Glutamine; Humans; Male; Nutritional Status; Ornithine; Phenylketonurias | 2011 |
Protective effect of L-citrulline against acute gastric mucosal lesions induced by ischemia-reperfusion in rats.
Topics: Amidines; Animals; Arginine; Benzylamines; Celiac Artery; Citrulline; Enzyme Inhibitors; Gastric Mucosa; Hexosamines; Ligation; Male; Malondialdehyde; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxidase; Protective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stomach | 2011 |
Arginine bioavailability ratios are associated with cardiovascular mortality in patients referred to coronary angiography.
Topics: Aged; Arginine; Cardiovascular Diseases; Chromatography; Citrulline; Coronary Angiography; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Intercellular Adhesion Molecule-1; Male; Middle Aged; Models, Biological; Nitric Oxide; Ornithine; Proportional Hazards Models; Vascular Cell Adhesion Molecule-1 | 2011 |
The effect of L-arginine or L-citrulline supplementation on biochemical parameters and the vascular aortic wall in high-fat and high-cholesterol-fed rats.
Topics: Administration, Oral; Alanine Transaminase; Animals; Anticholesteremic Agents; Antioxidants; Aorta; Arginine; Aspartate Aminotransferases; Body Weight; Cholesterol; Citrulline; Creatinine; Diet; Dietary Fats; Endothelium, Vascular; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Lipid Metabolism; Male; Microscopy, Electron, Transmission; Muscle, Smooth, Vascular; Nitric Oxide; Rats; Tunica Intima; Urea | 2011 |
L-NAME treatment enhances exercise-induced content of myocardial heat shock protein 72 (Hsp72) in rats.
Topics: Animals; Arginine; Blotting, Western; Citrulline; Heart Ventricles; Hemodynamics; HSP72 Heat-Shock Proteins; Male; Motor Activity; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Phosphorylation; Rats; Rats, Wistar; Tritium | 2011 |
Relative contribution of different l-arginine sources to the substrate supply of endothelial nitric oxide synthase.
Topics: Arginine; Atherosclerosis; Biological Transport; Cell Line; Chloroquine; Chromatography, High Pressure Liquid; Citrulline; Dipeptides; Endothelium, Vascular; Genes, Reporter; Histidine; Human Umbilical Vein Endothelial Cells; Humans; Leupeptins; Lysosomes; Membrane Transport Proteins; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteolysis | 2011 |
Bothrops jararaca peptide with anti-hypertensive action normalizes endothelium dysfunction involved in physiopathology of preeclampsia.
Topics: Amino Acid Sequence; Animals; Antihypertensive Agents; Arginine; Argininosuccinate Synthase; Blotting, Western; Bothrops; Calcium; Cells, Cultured; Citrulline; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Superoxides; Viper Venoms | 2011 |
Endotoxemia affects citrulline, arginine and glutamine bioavailability.
Topics: Animals; Area Under Curve; Arginine; Biological Availability; Citrulline; Disease Models, Animal; Endotoxemia; Glutamine; Lipopolysaccharides; Male; Random Allocation; Rats; Rats, Sprague-Dawley | 2012 |
Arginine or citrulline associated with a statin stimulates nitric oxide production in bovine aortic endothelial cells.
Topics: Animals; Aorta; Arginine; Argininosuccinate Lyase; Cattle; Caveolin 1; Citrulline; Drug Interactions; Endothelial Cells; Gene Expression Regulation, Enzymologic; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Simvastatin | 2011 |
Systemic L-citrulline prevents cerebral vasospasm in haptoglobin 2-2 transgenic mice after subarachnoid hemorrhage.
Topics: Animals; Arginine; Basilar Artery; Cerebrovascular Circulation; Citrulline; Disease Models, Animal; Dose-Response Relationship, Drug; Genotype; Haptoglobins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2012 |
Ornithine transcarbamylase deficiency presenting as recurrent abdominal pain in childhood.
Topics: Abdominal Pain; Alkalosis, Respiratory; Arginine; Carbamoyl-Phosphate Synthase I Deficiency Disease; Child, Preschool; Citrulline; Consciousness Disorders; Diagnosis, Differential; Diet, Protein-Restricted; Emergencies; Exons; Female; Glutamine; Humans; Hyperammonemia; Language Development Disorders; Liver Transplantation; Mutation, Missense; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Phenylbutyrates; Recurrence | 2011 |
Cytotoxicity of human recombinant arginase I (Co)-PEG5000 in the presence of supplemental L-citrulline is dependent on decreased argininosuccinate synthetase expression in human cells.
Topics: Antineoplastic Agents; Arginase; Arginine; Argininosuccinate Synthase; Cell Line, Tumor; Cell Proliferation; Citrulline; Culture Media; Drug Screening Assays, Antitumor; Epithelial Cells; Humans; Male; Ornithine Carbamoyltransferase; Polyethylene Glycols; Protein Synthesis Inhibitors; Recombinant Proteins | 2012 |
Nitric oxide synthase assays.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Chromatography, Thin Layer; Citrulline; Humans; Mice; Nitric Oxide Synthase; Rats; Tissue Extracts | 2001 |
Citrulline: a potential immunomodulator in sepsis.
Topics: Animals; Arginine; Citrulline; Disease Models, Animal; Endothelial Cells; Immunologic Factors; Inflammation Mediators; Interleukin-10; Interleukin-6; Interleukin-8; Nitric Oxide; Rats; Rats, Wistar; Sepsis | 2011 |
Site-specific incorporation of arginine analogs into proteins using arginyl-tRNA synthetase.
Topics: Amino Acid Sequence; Aminoacylation; Arginine; Arginine-tRNA Ligase; Catalysis; Citrulline; Homoarginine; Methylation; Molecular Sequence Data; omega-N-Methylarginine; Protein Biosynthesis | 2011 |
Pretreatment with citrulline improves gut barrier after intestinal obstruction in mice.
Topics: Animals; Arginine; Bacterial Translocation; Citrulline; Escherichia coli; Ileum; Immunoglobulin A, Secretory; Interferon-gamma; Intestinal Mucosa; Intestinal Obstruction; Male; Mice; Pentetic Acid; Permeability | 2012 |
Orally administered L-ornithine elevates brain L-ornithine levels and has an anxiolytic-like effect in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Arginine; Behavior, Animal; Brain; Cerebral Cortex; Citrulline; Dietary Supplements; Exploratory Behavior; Hippocampus; Male; Mice; Mice, Inbred ICR; Ornithine; Stress, Psychological; Time Factors | 2011 |
The role of asymmetric dimethyl arginine and oxidant/antioxidant system in preeclampsia.
Topics: Adult; Antioxidants; Arginine; Case-Control Studies; Citrulline; Female; Fetal Blood; Humans; Lipid Peroxidation; Malondialdehyde; Oxidants; Oxidative Stress; Pre-Eclampsia; Pregnancy; Young Adult | 2011 |
Spectroscopic, catalytic and binding properties of Bacillus subtilis NO synthase-like protein: comparison with other bacterial and mammalian NO synthases.
Topics: Animals; Arginine; Bacillus subtilis; Bacteria; Bacterial Proteins; Binding Sites; Biocatalysis; Biopterins; Citrulline; Ferric Compounds; Ferrous Compounds; Heme; Hydrogen Peroxide; Imidazoles; Kinetics; Mammals; Nitric Oxide Synthase; Oxidation-Reduction; Protein Binding; Recombinant Proteins; Species Specificity; Spectrophotometry | 2012 |
Continuous exposure to L-arginine induces oxidative stress and physiological tolerance in cultured human endothelial cells.
Topics: Arginase; Arginine; Ascorbic Acid; Cells, Cultured; Citrulline; Culture Media; Down-Regulation; Drug Tolerance; Free Radical Scavengers; Gene Expression; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Polyethylene Glycols; Superoxide Dismutase; Superoxides | 2012 |
Systemic arginine depletion after a murine model of surgery or trauma.
Topics: Adult; Alanine Transaminase; Animals; Arginase; Arginine; Aspartate Aminotransferases; Citrulline; Humans; Laparotomy; Male; Mice; Mice, Inbred C57BL; Middle Aged; Models, Animal; Ornithine; Wounds and Injuries; Young Adult | 2012 |
Endotoxemia exacerbates kidney injury and increases asymmetric dimethylarginine in young bile duct-ligated rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Kidney Injury; Animals; Arginine; Bile Ducts; Blotting, Western; Chromatography, High Pressure Liquid; Citrulline; Deoxyguanosine; Endotoxemia; Immunohistochemistry; Male; Rats; Rats, Sprague-Dawley | 2012 |
Arginine and ornithine are the main precursors for citrulline synthesis in mice.
Topics: Animals; Arginine; Carbon Isotopes; Citrulline; Deuterium; Infusions, Intravenous; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; Models, Biological; Nitrogen Isotopes; Ornithine | 2012 |
Restoration of impaired nitric oxide production in MELAS syndrome with citrulline and arginine supplementation.
Topics: Adolescent; Adult; Arginine; Case-Control Studies; Citrulline; Dietary Supplements; Female; Humans; Male; MELAS Syndrome; Middle Aged; Nitric Oxide; Prognosis; Young Adult | 2012 |
Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.
Topics: Animals; Apoptosis; Arginine; Cell Nucleus; Chromatin; Citrulline; DNA; DNA Damage; Gene Expression Regulation; Histones; Humans; Hydrolases; Lamin Type A; Mice; Mice, Transgenic; Models, Biological; Protein Structure, Tertiary; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Tumor Suppressor Protein p53 | 2012 |
An in silico model of enterocytic glutamine to citrulline conversion pathway.
Topics: Animals; Arginine; Citrulline; Computer Simulation; Enterocytes; Fasting; Glutamine; Humans; Kinetics; Mice; Models, Biological; Ornithine; Ornithine-Oxo-Acid Transaminase | 2012 |
Nitric oxide and L-arginine metabolism in a devascularized porcine model of acute liver failure.
Topics: Animals; Arginase; Arginine; Citrulline; Disease Models, Animal; Female; Liver; Liver Failure, Acute; Nitric Oxide; Ornithine; Portacaval Shunt, Surgical; Sus scrofa | 2012 |
L-citrulline prevents alveolar and vascular derangement in a rat model of moderate hyperoxia-induced lung injury.
Topics: Animals; Animals, Newborn; Arginine; Citrulline; Disease Models, Animal; Endothelium, Vascular; Female; Hyperoxia; Lung; Lung Injury; Matrix Metalloproteinase 2; Nitric Oxide; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Vascular Endothelial Growth Factor A | 2012 |
Hyperammonemia in a patient with late-onset ornithine carbamoyltransferase deficiency.
Topics: Age of Onset; Ammonia; Arginine; Citrulline; Humans; Hyperammonemia; Male; Middle Aged; Ornithine; Ornithine Carbamoyltransferase Deficiency Disease; Pedigree; Renal Dialysis; Sodium Benzoate | 2012 |
Influence of wine-like conditions on arginine utilization by lactic acid bacteria.
Topics: Arginine; Beer; Citrulline; Ethanol; Hydrogen-Ion Concentration; Lactobacillus; Malates; Pediococcus; Wine | 2011 |
Citrulline a more suitable substrate than arginine to restore NO production and the microcirculation during endotoxemia.
Topics: Animals; Arginine; Biological Availability; Citrulline; Dietary Supplements; Endotoxemia; Gene Expression Regulation, Enzymologic; Intracellular Space; Male; Mice; Mice, Inbred C57BL; Microcirculation; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III | 2012 |
Wine composition plays an important role in the control of carcinogenic precursor formation by Lactobacillus hilgardii X₁B.
Topics: Argentina; Arginine; Carboxylic Acids; Carcinogens; Citric Acid; Citrulline; Fructose; Fruit; Glucose; Hexoses; Humans; Hydrogen-Ion Concentration; Hydrolases; Hydroxybenzoates; Lactobacillus; Malates; Species Specificity; Urethane; Vitis; Wine | 2013 |
Lactic acid bacteria isolated from apples are able to catabolise arginine.
Topics: Ammonia; Arginine; Bacterial Load; Bacterial Typing Techniques; Citrulline; Culture Media; DNA, Bacterial; DNA, Ribosomal; Hydrogen-Ion Concentration; Lactobacillales; Malus; Molecular Sequence Data; RNA, Ribosomal, 16S; Sequence Analysis, DNA | 2012 |
Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation.
Topics: Animals; Arginine; Biocatalysis; Cell Line, Tumor; Chromatin; Citrulline; Estrogen Receptor alpha; Estrogens; Gene Expression Regulation, Neoplastic; Genome, Human; Histones; Humans; Hydrolases; Mice; Nucleotide Motifs; Promoter Regions, Genetic; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Response Elements; Transcription, Genetic; Transcriptional Activation | 2012 |
High sensitivity measurement of amino acid isotope enrichment using liquid chromatography-mass spectrometry.
Topics: Amino Acids; Animals; Arginine; Chromatography, High Pressure Liquid; Citrulline; Endotoxemia; Isotope Labeling; Isotopes; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Radioactive Tracers; Reproducibility of Results; Sensitivity and Specificity | 2012 |
Sustained generation of nitric oxide and control of mycobacterial infection requires argininosuccinate synthase 1.
Topics: Animals; Arginine; Argininosuccinate Synthase; Cells, Cultured; Citrulline; Macrophages; Mice; Mycobacterium bovis; Nitric Oxide | 2012 |
Crystal structures of arginine kinase in complex with ADP, nitrate, and various phosphagen analogs.
Topics: Adenosine Diphosphate; Animals; Arginine; Arginine Kinase; Catalytic Domain; Citrulline; Crystallography, X-Ray; Horseshoe Crabs; Nitrates; Protein Structure, Tertiary | 2012 |
Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease.
Topics: Adult; Amino Acid Sequence; Arginine; Chromatography, High Pressure Liquid; Citrulline; Coronary Artery Disease; Endothelium, Vascular; Erythrocytes; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Humans; Immunoprecipitation; Mass Spectrometry; Microscopy, Confocal; Molecular Sequence Data; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxyhemoglobins; Sequence Alignment; Sequence Analysis, Protein; Sequence Homology, Amino Acid | 2012 |
Arginine and citrulline protect intestinal cell monolayer tight junctions from hypoxia-induced injury in piglets.
Topics: Animals; Animals, Newborn; Arginine; Cell Line; Citrulline; Intestinal Mucosa; Lipid Peroxidation; Swine; Tight Junctions | 2012 |
De novo synthesis is the main source of ornithine for citrulline production in neonatal pigs.
Topics: Amino Acids; Animals; Animals, Newborn; Arginine; Biosynthetic Pathways; Carbon Isotopes; Citrulline; Female; Glutamine; Intestinal Mucosa; Ornithine; Proline; Radioactive Tracers; Swine | 2012 |
Chronic hypoxia decreases arterial and venous compliance in isolated perfused rat lungs: an effect that is reversed by exogenous L-arginine.
Topics: Animals; Arginine; Blood Pressure; Chronic Disease; Citrulline; Compliance; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lung; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Perfusion; Pulmonary Artery; Pulmonary Veins; Rats; Rats, Sprague-Dawley; Time Factors; Vascular Resistance; Vasoconstriction; Ventricular Dysfunction, Right | 2013 |
Effect of ethanol and low pH on citrulline and ornithine excretion and arc gene expression by strains of Lactobacillus brevis and Pediococcus pentosaceus.
Topics: Arginine; Bacterial Proteins; Citrulline; Ethanol; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Hydrogen-Ion Concentration; Levilactobacillus brevis; Ornithine; Pediococcus; Phosphotransferases (Carboxyl Group Acceptor); Wine | 2013 |
Dimethylarginine-dimethylaminohydrolase-2 (DDAH-2) does not metabolize methylarginines.
Topics: Amidohydrolases; Animals; Arginine; Citrulline; Enzyme Assays; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Spleen; Swine; Thyroid Gland | 2012 |
Oligonucleotide-peptide conjugates: solid-phase synthesis under acidic conditions and use in ELISA assays.
Topics: Antibodies; Arginine; Arthritis, Rheumatoid; Citrulline; Epitopes; Fibrin; Filaggrin Proteins; Humans; Intermediate Filament Proteins; Oligonucleotides; Peptides; Solid-Phase Synthesis Techniques | 2012 |
A putative transport protein is involved in citrulline excretion and re-uptake during arginine deiminase pathway activity by Lactobacillus sakei.
Topics: Arginine; Bacterial Proteins; Biological Transport, Active; Carrier Proteins; Citrulline; Gene Expression; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Hydrogen-Ion Concentration; Hydrolases; Lactobacillus; Mutation; Ornithine | 2013 |
Aminoguanidine attenuates hypertension, whereas 7-nitroindazole exacerbates kidney damage in spontaneously hypertensive rats: the role of nitric oxide.
Topics: Amidohydrolases; Animals; Arginine; Blood Pressure; Citrulline; Guanidines; Hypertension; Indazoles; Kidney Diseases; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Inbred SHR; Sodium Chloride, Dietary; Up-Regulation | 2013 |
Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling.
Topics: Animals; Antigens, Surface; Arginine; Arthritis, Rheumatoid; Binding Sites; Calreticulin; Cell Line; Citrulline; Epitopes; Fibroblasts; Gene-Environment Interaction; HLA-DRB1 Chains; Humans; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Recombinant Proteins; Signal Transduction; Surface Plasmon Resonance; Synovial Membrane | 2013 |
Serum homocysteine, arginine, citrulline and asymmetric dimethyl arginine levels, and histopathologic examination of the abdominal aorta in rats exposed to acrylamide.
Topics: Acrylamide; Animals; Aorta, Abdominal; Arginine; Carcinogens; Citrulline; Female; Homocysteine; Male; Rats; Rats, Wistar; Reference Standards | 2013 |
Effect of major and minor surgery on plasma levels of arginine, citrulline, nitric oxide metabolites, and ornithine in humans.
Topics: Adult; Arginine; Citrulline; Female; Humans; Laparotomy; Middle Aged; Minor Surgical Procedures; Nitric Oxide; Ornithine; Prospective Studies; Vulvar Diseases | 2013 |
Matrix-assisted laser desorption ionization-time of flight mass spectrometry identification of peptide citrullination site using Br signature.
Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Bromine; Cattle; Citrulline; Fibrinogen; Glyoxal; Peptides; Serum Albumin, Bovine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
Circulating microparticles carry a functional endothelial nitric oxide synthase that is decreased in patients with endothelial dysfunction.
Topics: Adult; Arginine; Biomarkers; Blotting, Western; Case-Control Studies; Cell-Derived Microparticles; Cells, Cultured; Citrulline; Coronary Stenosis; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Immunoprecipitation; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Reactive Oxygen Species; Time Factors; Vasodilation; Young Adult | 2012 |
Substrate selectivity in arginine-dependent acid resistance in enteric bacteria.
Topics: Amino Acid Transport Systems; Antiporters; Arginine; Bacterial Proteins; Biological Transport; Carbon Isotopes; Catalysis; Citrulline; Enterobacteriaceae; Hydrogen-Ion Concentration; Liposomes; Potassium; Protein Conformation; Protons; Substrate Specificity | 2013 |
Methylated N(ω)-hydroxy-L-arginine analogues as mechanistic probes for the second step of the nitric oxide synthase-catalyzed reaction.
Topics: Animals; Arginine; Catalysis; Chromatography, High Pressure Liquid; Citrulline; Crystallography, X-Ray; Kinetics; Mass Spectrometry; Methylation; Models, Molecular; Molecular Probes; NADP; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Substrate Specificity | 2013 |
Successful early management of a female patient with a metabolic stroke due to ornithine transcarbamylase deficiency.
Topics: Adolescent; Arginine; Brain; Carnitine; Case Management; Citrulline; Coma; Combined Modality Therapy; Drug Therapy, Combination; Electroencephalography; Female; Glutamates; Hemofiltration; Humans; Hyperammonemia; Lethargy; Ornithine Carbamoyltransferase Deficiency Disease; Phenylbutyrates; Renal Dialysis; Tomography, Emission-Computed, Single-Photon; Vomiting | 2013 |
Facile fluorescence-based detection of PAD4-mediated citrullination.
Topics: Arginine; Citrulline; Enzyme Assays; Humans; Hydrolases; Models, Molecular; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Spectrometry, Fluorescence; Substrate Specificity; Trypsin | 2013 |
Unilateral nephrectomy causes an early abrupt decrease in plasma arginine and simultaneous reduction in glomerular filtration rate in living kidney donors.
Topics: Arginine; Citrulline; Creatinine; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Transplantation; Living Donors; Male; Middle Aged; Nephrectomy; Nitric Oxide; Nitrites; Ornithine; Phenylalanine; Thiobarbituric Acid Reactive Substances; Urea | 2013 |
Malaria-associated L-arginine deficiency induces mast cell-associated disruption to intestinal barrier defenses against nontyphoidal Salmonella bacteremia.
Topics: Animals; Arginine; Bacteremia; Citrulline; Female; Intestines; Malaria; Mast Cells; Mice; Permeability; Plasmodium yoelii; Salmonella Infections, Animal | 2013 |
Circulating blood endothelial nitric oxide synthase contributes to the regulation of systemic blood pressure and nitrite homeostasis.
Topics: Animals; Arginine; Blood Pressure; Carbon Radioisotopes; Citrulline; Endothelium, Vascular; Enzyme Inhibitors; Erythrocytes; Homeostasis; Hypertension; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Signal Transduction | 2013 |
Cross-sectional observational study of 208 patients with non-classical urea cycle disorders.
Topics: Adolescent; Adult; Age of Onset; Aged; Arginine; Child; Child, Preschool; Citrulline; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Diet Therapy; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Neonatal Screening; Ornithine Carbamoyltransferase Deficiency Disease; Time Factors; Treatment Outcome; Urea Cycle Disorders, Inborn; Young Adult | 2014 |
Insights into the arginine paradox: evidence against the importance of subcellular location of arginase and eNOS.
Topics: Animals; Aorta; Arginase; Arginine; Cattle; Cell Line; Cells, Cultured; Chlorocebus aethiops; Citrulline; COS Cells; Endothelium, Vascular; Models, Animal; Nitric Oxide; Nitric Oxide Synthase Type III; Ornithine | 2013 |
Increased erythrocytes by-products of arginine catabolism are associated with hyperglycemia and could be involved in the pathogenesis of type 2 diabetes mellitus.
Topics: Adult; Aged; Arginine; Blood Glucose; Carbon Isotopes; Case-Control Studies; Citrulline; Diabetes Mellitus, Type 2; Endothelial Cells; Erythrocytes; Female; Glycosylation; Hemoglobins; Hemolysis; Humans; Hyperglycemia; Male; Malondialdehyde; Metabolic Networks and Pathways; Middle Aged; Models, Biological; Nitric Oxide; Nitrites; Ornithine; Oxidative Stress; Urea | 2013 |
Reduced plasma citrulline levels in low birth weight infants with necrotizing enterocolitis.
Topics: Arginine; Citrulline; Enterocolitis, Necrotizing; Female; Glutamine; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Prospective Studies | 2013 |
Porphyromonas gingivalis peptidylarginine deiminase substrate specificity.
Topics: Arginine; Citrulline; Enzyme Stability; Hydrogen-Ion Concentration; Hydrolases; Membrane Proteins; Peptides; Porphyromonas gingivalis; Protein-Arginine Deiminases; Substrate Specificity; Temperature | 2013 |
Decoding the substrate supply to human neuronal nitric oxide synthase.
Topics: Arginine; Cell Line; Citrulline; Enzyme Activation; Extracellular Space; Humans; Lysosomes; Neuroblastoma; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Proteasome Endopeptidase Complex; Proteolysis; Substrate Specificity | 2013 |
MALDI mass spectrometry-based sequence analysis of arginine-containing glycopeptides: improved fragmentation of glycan and peptide chains by modifying arginine residue.
Topics: Amino Acid Sequence; Arginine; Citrulline; Glycopeptides; Humans; Models, Chemical; Molecular Sequence Data; Polysaccharides; Sequence Analysis, Protein; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2013 |
Overexpression of arginine transporter CAT-1 is associated with accumulation of L-arginine and cell growth in human colorectal cancer tissue.
Topics: Aged; Arginine; Case-Control Studies; Cationic Amino Acid Transporter 1; Cell Line, Tumor; Cell Proliferation; Citrulline; Colorectal Neoplasms; Female; Gene Expression; Humans; Male; Middle Aged; Neoplasm Staging; RNA Interference | 2013 |
Changes in arginine metabolism during sepsis and critical illness in children.
Topics: Adult; Arginine; Child; Citrulline; Critical Illness; Dietary Supplements; Humans; Inflammation; Nitric Oxide; Sepsis | 2013 |
Two different approaches to restore renal nitric oxide and prevent hypertension in young spontaneously hypertensive rats: l-citrulline and nitrate.
Topics: Animals; Arginine; Citrulline; Dietary Supplements; Hypertension; Male; Nitrates; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2014 |
Streptococcus pyogenes arginine and citrulline catabolism promotes infection and modulates innate immunity.
Topics: Animals; Arginine; Citrulline; Disease Models, Animal; Gene Expression Regulation, Bacterial; Hydrolases; Immunity, Innate; Macrophages; Mice; Nitric Oxide Synthase Type II; Streptococcus pyogenes; Virulence | 2014 |
Cross-talk Between Nitrate-Nitrite-NO and NO Synthase Pathways in Control of Vascular NO Homeostasis.
Topics: Animals; Aorta; Arginine; Blood Pressure; Cardiovascular System; Citrulline; Dietary Supplements; Homeostasis; Male; Metabolic Networks and Pathways; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Phosphorylation; Rats, Sprague-Dawley | 2015 |
[Clinical effect of stem cell transplantation via hepatic artery in the treatment of type II hyperammonemia: a report on 6 cases].
Topics: AC133 Antigen; Ammonia; Antigens, CD; Arginine; Citrulline; Female; Glycoproteins; Hepatic Artery; Humans; Hyperammonemia; Infant; Male; Peptides; Stem Cell Transplantation | 2013 |
Citrulline uptake in rat cerebral cortex slices: modulation by Thioacetamide -Induced hepatic failure.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Cerebral Cortex; Citrulline; In Vitro Techniques; Kinetics; Liver Failure; Male; Nerve Tissue Proteins; Nitric Oxide; Rats; Rats, Sprague-Dawley; Thioacetamide | 2014 |
Citrullination regulates pluripotency and histone H1 binding to chromatin.
Topics: Animals; Arginine; Binding Sites; Cellular Reprogramming; Chromatin; Chromatin Assembly and Disassembly; Citrulline; DNA; Embryo, Mammalian; Gene Expression Regulation; Histones; Hydrolases; Mice; Pluripotent Stem Cells; Protein Binding; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Proteomics; Substrate Specificity; Transcription, Genetic | 2014 |
Arginase-1 deficiency regulates arginine concentrations and NOS2-mediated NO production during endotoxemia.
Topics: Animals; Arginase; Arginine; Cell Count; Citrulline; Cytokines; Endotoxemia; Integrases; Jejunum; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microcirculation; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Organ Specificity; Ornithine; Perfusion; Peroxidase; Receptor, TIE-2; RNA, Messenger | 2014 |
Ligand-dependent dynamics of the active-site lid in bacterial dimethylarginine dimethylaminohydrolase.
Topics: Amidohydrolases; Arginine; Catalytic Domain; Citrulline; Kinetics; Ligands; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Pseudomonas aeruginosa | 2014 |
The human peptidylarginine deiminases type 2 and type 4 have distinct substrate specificities.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Chlorocebus aethiops; Citrulline; COS Cells; Escherichia coli; Glycine; HEK293 Cells; Humans; Hydrolases; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Recombinant Proteins; Substrate Specificity; Tyrosine | 2014 |
Rapid enzymatic assays for L-citrulline and L-arginine based on the platform of pyrophosphate detection.
Topics: Arginine; Argininosuccinate Synthase; Bacterial Proteins; Blood Chemical Analysis; Citrulline; Diphosphates; Enzyme Assays; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Humans; Hydrolases; Propionibacterium; Pseudomonas aeruginosa; Pyruvate, Orthophosphate Dikinase; Recombinant Proteins; Urea | 2014 |
A novel method for simultaneous measurement of concentration and enrichment of NO synthesis-specific amino acids in human plasma using stable isotopes and LC/MS ion trap analysis.
Topics: Arginine; Chromatography, Liquid; Citrulline; Glutamine; Humans; Limit of Detection; Mass Spectrometry; Nitric Oxide | 2014 |
Amino acids as biomarker candidates for suicidality in male OEF/OIF Veterans: relevance to NMDA receptor modulation and nitric oxide signaling.
Topics: Afghan Campaign 2001-; Amino Acids; Arginine; Citrulline; Humans; Iraq War, 2003-2011; Male; Pilot Projects; Receptors, N-Methyl-D-Aspartate; Serine; Stress Disorders, Post-Traumatic; Suicidal Ideation; Veterans | 2014 |
Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner.
Topics: Amino Acid Motifs; Aminoacylation; Animals; Arginine; Bone Neoplasms; Cell Adhesion; Cell Line, Tumor; Cells, Cultured; Chickens; CHO Cells; Citrulline; Collagen Type II; Cricetinae; Cricetulus; Fibroblasts; Humans; Integrins; Mesenchymal Stem Cells; Osteoarthritis; Osteosarcoma; Peptide Fragments; Protein Binding; Protein Processing, Post-Translational; Rats; Recombinant Fusion Proteins; Synovial Membrane; Transfection | 2014 |
L-Citrulline, but not L-arginine, prevents diabetes mellitus-induced glomerular hyperfiltration and proteinuria in rat.
Topics: Animals; Arginine; Citrulline; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glomerular Filtration Rate; Kidney; Kidney Glomerulus; Oxygen Consumption; Proteinuria; Rats | 2014 |
Cultivation to improve in vivo solubility of overexpressed arginine deiminases in Escherichia coli and the enzyme characteristics.
Topics: Arginine; Bacterial Proteins; Base Sequence; Citrulline; Escherichia coli; Hydrogen-Ion Concentration; Hydrolases; Listeria; Molecular Chaperones; Molecular Sequence Data; Pseudomonas putida; Recombinant Proteins; Solubility | 2014 |
Simultaneous determination of citrulline and arginine in human blood plasma by capillary electrophoresis with ultraviolet absorption detection.
Topics: Adult; Aged; Amino Acids; Arginine; Citrulline; Electrophoresis, Capillary; Humans; Hypolipidemic Agents; Male; Middle Aged; Renal Insufficiency, Chronic; Spectrophotometry, Ultraviolet | 2014 |
Involvement of neuronal nitric oxide synthase in desensitisation of µ-opioid receptors in the rat locus coeruleus.
Topics: Action Potentials; Animals; Arginine; Citrulline; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ferricyanides; Indazoles; Locus Coeruleus; Male; Neural Inhibition; Nitric Oxide Synthase Type I; Nitroprusside; Norepinephrine; Ornithine; Rats; Receptors, Opioid, mu; Thiourea | 2014 |
Endothelial arginine resynthesis contributes to the maintenance of vasomotor function in male diabetic mice.
Topics: Acetylcholine; Animals; Arginase; Arginine; Argininosuccinate Synthase; Blood Pressure; Citrulline; Diabetes Mellitus, Experimental; Endothelial Cells; Endothelium; Female; Heart Rate; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Vasomotor System | 2014 |
Synthesis of Mycoplasma arginine deiminase in E. coli using stress-responsive proteins.
Topics: Arginine; Bacterial Proteins; Citrulline; Colorimetry; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Genes, Synthetic; Genetic Vectors; Hydrolases; Malate Dehydrogenase; Mycoplasma; Peptide Elongation Factors; Recombinant Fusion Proteins; Solubility | 2014 |
Extrarenal citrulline disposal in mice with impaired renal function.
Topics: Animals; Arginine; Citrulline; Ligation; Male; Mice; Mice, Inbred ICR; Nephrectomy; Renal Insufficiency | 2014 |
Granulocyte functions are independent of arginine availability.
Topics: Animals; Antineoplastic Agents; Apoptosis; Arginase; Arginine; Aspergillus fumigatus; Bronchoalveolar Lavage Fluid; Cells, Cultured; Chemotaxis, Leukocyte; Citrulline; Humans; Hydrolases; Immunity, Innate; Interleukin-8; Lung; Mice; Mice, Inbred C57BL; Neutrophils; Phagocytosis; Polyethylene Glycols; Primary Cell Culture; Pulmonary Aspergillosis; Reactive Oxygen Species; Respiratory Burst | 2014 |
Renal response to L-arginine in diabetic rats. A possible link between nitric oxide system and aquaporin-2.
Topics: Animals; Aquaporin 2; Arginine; Blood Glucose; Citrulline; Diabetes Mellitus, Experimental; Kidney Medulla; Kidney Tubules, Collecting; Male; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Streptozocin | 2014 |
Is arginine/asymetric dimethylarginine ratio depletion an indicator of insufficient resuscitation in a porcine model of hemorrhage-reperfusion?
Topics: Animals; Arginine; Biomarkers; Chromatography, Liquid; Citrulline; Female; Fluid Therapy; Interleukin-6; Male; Mass Spectrometry; Resuscitation; Shock, Hemorrhagic; Sus scrofa | 2014 |
Enzymatic and cryoreduction EPR studies of the hydroxylation of methylated N(ω)-hydroxy-L-arginine analogues by nitric oxide synthase from Geobacillus stearothermophilus.
Topics: Animals; Arginine; Bacterial Proteins; Biocatalysis; Citrulline; Cold Temperature; Electron Spin Resonance Spectroscopy; Geobacillus stearothermophilus; Hydrogen Peroxide; Hydroxylation; Isomerism; Kinetics; Methylation; Mice; Models, Molecular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Protein Stability; Recombinant Proteins; Substrate Specificity | 2014 |
Diabetic nephropathy is resistant to oral L-arginine or L-citrulline supplementation.
Topics: Amino Acids; Animals; Arginase; Arginine; Blood Pressure; Citrulline; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Supplements; Fibronectins; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred DBA; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Tumor Necrosis Factor-alpha | 2014 |
Peptidyl arginine deiminase from Porphyromonas gingivalis abolishes anaphylatoxin C5a activity.
Topics: Arginine; Bacterial Proteins; Calcium; Cell Membrane; Cell Movement; Cells, Cultured; Chemotaxis; Citrulline; Complement C5a; Electrophoresis, Polyacrylamide Gel; Humans; Hydrolases; Mutation; Neutrophils; Porphyromonas gingivalis; Protein-Arginine Deiminases; Receptor, Anaphylatoxin C5a; Transport Vesicles; U937 Cells | 2014 |
Intravenous glutamine supplementation enhances renal de novo arginine synthesis in humans: a stable isotope study.
Topics: Administration, Intravenous; Aged; Arginine; Citrulline; Cross-Sectional Studies; Dietary Supplements; Dipeptides; Evaluation Studies as Topic; Female; Glutamine; Humans; Isotope Labeling; Kidney; Male; Middle Aged | 2014 |
First Bulgarian case of citrin deficiency caused by one novel and one recurrent mutation in the SLC25A13 gene.
Topics: Arginine; Bulgaria; Calcium-Binding Proteins; Citrulline; Citrullinemia; DNA Mutational Analysis; Female; Follow-Up Studies; Galactose; Genetic Carrier Screening; Humans; Infant, Newborn; Male; Methionine; Mitochondrial Membrane Transport Proteins; Mutation, Missense; Organic Anion Transporters; Phenotype; Pregnancy; White People | 2014 |
In vitro anti-inflammatory effects of citrulline on peritoneal macrophages in Zucker diabetic fatty rats.
Topics: Animals; Anti-Inflammatory Agents; Arginine; Blood Glucose; Citrulline; Diabetes Mellitus, Type 2; Interleukin-6; Macrophages, Peritoneal; Male; Nitric Oxide; Obesity; Rats; Rats, Zucker; Tumor Necrosis Factor-alpha | 2015 |
Oral supplementation with a combination of L-citrulline and L-arginine rapidly increases plasma L-arginine concentration and enhances NO bioavailability.
Topics: Administration, Oral; Animals; Arginine; Atherosclerosis; Biological Availability; Citrulline; Cyclic GMP; Dietary Supplements; Drug Synergism; Humans; Male; Nitric Oxide; Rabbits; Rats; Rats, Sprague-Dawley; Signal Transduction | 2014 |
Renal transplantation promptly restores excretory function but disturbed L-arginine metabolism persists in patients during the early period after surgery.
Topics: Adult; Arginine; Citrulline; Creatinine; Female; Humans; Kidney Transplantation; Male; Middle Aged; Nitric Oxide; Postoperative Complications; Young Adult | 2015 |
Effects of hyperbaric oxygen on nitric oxide generation in humans.
Topics: Adult; Arginine; Breath Tests; Citrulline; Cyclic GMP; Humans; Hyperbaric Oxygenation; Nitrates; Nitric Oxide; Nitrites; Oxygen; Saliva; Tongue; Young Adult | 2015 |
Rescue Treatment with L-Citrulline Inhibits Hypoxia-Induced Pulmonary Hypertension in Newborn Pigs.
Topics: Animals; Animals, Newborn; Arginine; Cell Hypoxia; Citrulline; Drug Evaluation, Preclinical; Hypertension, Pulmonary; Sus scrofa | 2015 |
Plasma levels of dimethylarginines in preterm very low birth weight neonates: its relation with perinatal factors and short-term outcome.
Topics: Arginine; Birth Weight; Chorioamnionitis; Citrulline; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Male; Nitric Oxide; Pre-Eclampsia; Pregnancy | 2014 |
PAD2 Activity Monitored via a Fluorescent Substrate Analog.
Topics: Arginine; Benzamides; Calcium; Citrulline; Coumarins; Enzyme Assays; Enzyme Inhibitors; Fluorescent Dyes; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Spectrometry, Fluorescence; Trypsin | 2015 |
[Citrulline and arginine kinetics and its value as a prognostic factor in pediatric critically ill patients].
Topics: Adolescent; Arginine; Child; Child, Preschool; Citrulline; Critical Illness; Female; Humans; Infant; Infant, Newborn; Intensive Care Units, Pediatric; Kinetics; Male; Prognosis; Prospective Studies; Severity of Illness Index; Systemic Inflammatory Response Syndrome; Time Factors | 2015 |
Effect of specific amino acids on hepatic lipid metabolism in fructose-induced non-alcoholic fatty liver disease.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Arginine; Aspartate Aminotransferases; Bilirubin; Blood Glucose; Cholesterol; Citrulline; Dietary Supplements; Fructose; Glutamine; Hypertriglyceridemia; Insulin; Insulin Resistance; Intestinal Absorption; Lipid Metabolism; Liver; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; RNA, Messenger; Toll-Like Receptor 4; Triglycerides; Tumor Necrosis Factor-alpha | 2016 |
Indian women of childbearing age do not metabolically conserve arginine as do American and Jamaican women.
Topics: Adult; Arginine; Body Composition; Carbon Isotopes; Citrulline; Deuterium; Energy Metabolism; Female; Humans; India; Indicator Dilution Techniques; Jamaica; Meals; Models, Biological; Nitrogen Isotopes; Nutritional Requirements; Ornithine; Phenylalanine; Texas | 2015 |
Dietary arginine requirements for growth are dependent on the rate of citrulline production in mice.
Topics: Animals; Arginine; Carbamoyl-Phosphate Synthase (Ammonia); Citrulline; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Nutritional Requirements; Ornithine Carbamoyltransferase; Weaning | 2015 |
L-Citrulline dilates rat retinal arterioles via nitric oxide- and prostaglandin-dependent pathways in vivo.
Topics: Animals; Arginine; Argininosuccinate Synthase; Citrulline; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Prostaglandins; Rats, Wistar; Retinal Artery; Signal Transduction; Vasodilation | 2015 |
Plasma arginine metabolites reflect airway dysfunction in a murine model of allergic airway inflammation.
Topics: Animals; Arginase; Arginine; Asthma; Bronchoconstrictor Agents; Citrulline; Enzyme Inhibitors; Female; Methacholine Chloride; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase; Ornithine; Ovalbumin; Respiratory System | 2015 |
Enzymatic production of l-citrulline by hydrolysis of the guanidinium group of l-arginine with recombinant arginine deiminase.
Topics: Arginine; Bacterial Proteins; Citrulline; Escherichia coli; Guanidine; Hydrolases; Lactococcus lactis; Recombinant Proteins | 2015 |
L-citrulline for protection of endothelial function from ADMA-induced injury in porcine coronary artery.
Topics: Animals; Arginine; Cardiovascular Agents; Citrulline; Coronary Vessels; Cyclic GMP; Drug Evaluation, Preclinical; Endothelium, Vascular; Nitric Oxide Synthase Type III; Phosphorylation; Protein Processing, Post-Translational; Superoxides; Sus scrofa; Vascular System Injuries | 2015 |
Oral Citrulline Mitigates Inflammation and Jejunal Damage via the Inactivation of Neuronal Nitric Oxide Synthase and Nuclear Factor-κB in Intestinal Ischemia and Reperfusion.
Topics: Animals; Apoptosis; Arginine; Cell Proliferation; Citrulline; Cytokines; Glutamine; Inflammation; Interferon-gamma; Jejunum; Male; NF-kappa B; Nitric Oxide Synthase Type I; Ornithine; Rats; Rats, Wistar; Reperfusion Injury | 2017 |
Citrulline Supplementation Improves Organ Perfusion and Arginine Availability under Conditions with Enhanced Arginase Activity.
Topics: Animals; Arginase; Arginine; Citrulline; Jejunum; Male; Mice; Mice, Inbred C57BL; Microcirculation; Nitric Oxide | 2015 |
Extracellular expression of natural cytosolic arginine deiminase from Pseudomonas putida and its application in the production of L-citrulline.
Topics: Actinomycetales; Arginine; Bioreactors; Carboxylic Ester Hydrolases; Citrulline; Culture Media; Escherichia coli; Fermentation; Hydrolases; Lactose; Pseudomonas putida | 2015 |
Citrulline and Nonessential Amino Acids Prevent Fructose-Induced Nonalcoholic Fatty Liver Disease in Rats.
Topics: Algorithms; Amino Acids; Animals; Arginine; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Biomarkers; Citrulline; Dietary Supplements; Fatty Acid Synthase, Type I; Fructose; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Humans; Insulin Resistance; Liver; Male; Non-alcoholic Fatty Liver Disease; Ornithine; PPAR alpha; Random Allocation; Rats, Sprague-Dawley; Sterol Regulatory Element Binding Protein 1 | 2015 |
Prazosin-Conjugated Matrices Based on Biodegradable Polymers and α-Amino Acids--Synthesis, Characterization, and in Vitro Release Study.
Topics: Adrenergic alpha-1 Receptor Antagonists; Aliivibrio fischeri; Amino Acids; Antihypertensive Agents; Arginine; Calorimetry, Differential Scanning; Caproates; Ciliophora; Citrulline; Drug Delivery Systems; Imidazoles; Lactones; Magnetic Resonance Spectroscopy; Nuclear Magnetic Resonance, Biomolecular; Polyesters; Prazosin | 2015 |
Differential Requirements for L-Citrulline and L-Arginine during Antimycobacterial Macrophage Activity.
Topics: Animals; Arginase; Arginine; Cells, Cultured; Citrulline; Interferon-gamma; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mycobacterium bovis; Nitric Oxide; Nitric Oxide Synthase Type II; Tuberculosis | 2015 |
Acute ingestion of citrulline stimulates nitric oxide synthesis but does not increase blood flow in healthy young and older adults with heart failure.
Topics: Adult; Aged; Arginine; Cardiovascular Agents; Citrulline; Dietary Supplements; Elder Nutritional Physiological Phenomena; Endothelium, Vascular; Female; Forearm; Heart Failure; Humans; Hyperemia; Kinetics; Male; Middle Aged; Nitric Oxide; Regional Blood Flow; Severity of Illness Index; Up-Regulation; Young Adult | 2015 |
Synthetic Peptide-Based ELISA and ELISpot Assay for Identifying Autoantibody Epitopes.
Topics: Arginine; Autoantibodies; Avidin; B-Lymphocytes; Cell Separation; Citrulline; Enzyme-Linked Immunosorbent Assay; Enzyme-Linked Immunospot Assay; Epitope Mapping; Humans; Peptides | 2016 |
Global arginine bioavailability, a marker of nitric oxide synthetic capacity, is decreased in PTSD and correlated with symptom severity and markers of inflammation.
Topics: Adult; Arginine; Biological Availability; Biomarkers; C-Reactive Protein; Case-Control Studies; Citrulline; Depressive Disorder; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Male; Nitric Oxide; Ornithine; Psychiatric Status Rating Scales; Stress Disorders, Post-Traumatic; Veterans | 2016 |
Controlling the transcription levels of argGH redistributed L-arginine metabolic flux in N-acetylglutamate kinase and ArgR-deregulated Corynebacterium crenatum.
Topics: Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Bacterial Proteins; Biosynthetic Pathways; Citrulline; Corynebacterium; Feedback, Physiological; Fermentation; Gene Expression Regulation, Bacterial; Genes, Bacterial; Metabolic Flux Analysis; Ornithine; Phosphotransferases (Carboxyl Group Acceptor); Transcription, Genetic | 2016 |
Serine 1179 Phosphorylation of Endothelial Nitric Oxide Synthase Increases Superoxide Generation and Alters Cofactor Regulation.
Topics: Animals; Arginine; Biopterins; Calcium; Calmodulin; Cattle; Cell Survival; Citrulline; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; HEK293 Cells; Humans; Mutation; NADP; Nitric Oxide Synthase Type III; Oxygen; Phosphorylation; Reactive Oxygen Species; Recombinant Proteins; Serine; Spin Trapping; Superoxides; Vascular Endothelial Growth Factor A | 2015 |
Nitric oxide synthesis capacity, ambulatory blood pressure and end organ damage in a black and white population: the SABPA study.
Topics: Adult; Aged; Arginine; Biomarkers; Black People; Blood Pressure; Carotid Intima-Media Thickness; Citrulline; Cross-Sectional Studies; Female; Homoarginine; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; South America; White People | 2016 |
High salt exacerbates programmed hypertension in maternal fructose-fed male offspring.
Topics: Analysis of Variance; Animals; Animals, Newborn; Arginine; Blotting, Western; Chromatography, High Pressure Liquid; Citrulline; Female; Fructose; Hypertension; Male; Nitric Oxide; Pregnancy; Pregnancy, Animal; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reference Values; Renin-Angiotensin System; Sodium Chloride, Dietary; Survival Rate | 2015 |
Arginine behaviour after arginine or citrulline administration in older subjects.
Topics: Aged; Amino Acids; Arginine; Body Mass Index; Citrulline; Dietary Supplements; Fasting; Humans; Male; Ornithine | 2016 |
Changes in Biliary Levels of Arginine and its Methylated Derivatives after Hepatic Ischaemia/Reperfusion.
Topics: Alanine Transaminase; Alkaline Phosphatase; Amidohydrolases; Amino Acid Transport Systems, Basic; Animals; Arginine; Aspartate Aminotransferases; Bile; Citrulline; Liver; Liver Diseases; Male; Nitric Oxide; Rats; Rats, Wistar; Reperfusion Injury; RNA, Messenger | 2016 |
Protein Arginine Methylation and Citrullination in Epigenetic Regulation.
Topics: Arginine; Chromatin; Citrulline; Epigenesis, Genetic; Humans; Methylation | 2016 |
Age-dependent damage of hair cuticle: contribution of S100A3 protein and its citrullination.
Topics: Adolescent; Adult; Age Factors; Aged; Arginine; Citrulline; Female; Hair; Humans; Hygiene; Middle Aged; S100 Proteins; Skin Aging; Stress, Mechanical; Young Adult | 2016 |
Low urinary citrulline/arginine ratio associated with blood pressure abnormalities and arterial stiffness in childhood chronic kidney disease.
Topics: Adolescent; Arginine; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Child; Citrulline; Female; Humans; Hypertension; Male; Nitric Oxide; Nitric Oxide Synthase; Pulse Wave Analysis; Renal Insufficiency, Chronic; Taiwan; Vascular Remodeling; Vascular Stiffness | 2016 |
[The value of the kinetics of citrulline and arginine as a prognostic factor in critically ill paediatric patients].
Topics: Arginine; Child; Citrulline; Critical Illness; Humans; Intensive Care Units; Kinetics | 2016 |
Impaired nitric oxide production in children with MELAS syndrome and the effect of arginine and citrulline supplementation.
Topics: Adolescent; Arginine; Case-Control Studies; Child; Child, Preschool; Citrulline; Dietary Supplements; Female; Humans; Male; MELAS Syndrome; Nitric Oxide; Treatment Outcome | 2016 |
L-Citrulline Supplementation Enhances Fetal Growth and Protein Synthesis in Rats with Intrauterine Growth Restriction.
Topics: Animals; Arginine; Citrulline; Diet, Protein-Restricted; Dietary Supplements; Female; Fetal Development; Fetal Growth Retardation; Fetal Weight; Fetus; Maternal Nutritional Physiological Phenomena; Nitric Oxide; Nutritional Status; Placenta; Pregnancy; Protein Biosynthesis; Rats; Rats, Sprague-Dawley | 2016 |
Characterization and Localization of Citrullinated Proteoglycan Aggrecan in Human Articular Cartilage.
Topics: Adult; Aggrecans; Antibody Specificity; Arginine; Arthritis, Rheumatoid; Blotting, Western; Cartilage, Articular; Citrulline; Complex Mixtures; Epitopes; Humans; Immunohistochemistry; Osteoarthritis; Protein Structure, Tertiary; Tissue Extracts | 2016 |
Plasma kallikrein-bradykinin pathway promotes circulatory nitric oxide metabolite availability during hypoxia.
Topics: Acclimatization; Adult; Altitude; Angiotensinogen; Arginine; Bradykinin; Citrulline; Humans; Hypoxia; Isoprostanes; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Oxidative Stress; Plasma Kallikrein; Protein Carbonylation; Proteome; Signal Transduction | 2016 |
L-Arginine Availability and Metabolism Is Altered in Ulcerative Colitis.
Topics: Amino Acid Transport Systems, Basic; Amino Acids; Arginase; Arginine; Biological Availability; Case-Control Studies; Citrulline; Clinical Trials as Topic; Colitis, Ulcerative; Colon; Crohn Disease; Diet Records; Humans; Nitric Oxide Synthase Type II; Prospective Studies; RNA, Messenger; Severity of Illness Index | 2016 |
Reduced arginine availability and nitric oxide synthesis in cancer is related to impaired endogenous arginine synthesis.
Topics: Aged; Amino Acids; Arginine; Carcinoma, Non-Small-Cell Lung; Citrulline; Humans; Lung Neoplasms; Male; Middle Aged; Nitric Oxide | 2016 |
Alterations in whole-body arginine metabolism in chronic obstructive pulmonary disease.
Topics: Aged; Amino Acids; Arginine; Citrulline; Female; Forced Expiratory Volume; Humans; Kinetics; Lung; Male; Middle Aged; Nitric Oxide; Protein Biosynthesis; Proteins; Pulmonary Disease, Chronic Obstructive | 2016 |
Amino acid metabolism reflecting arginase activity is increased in patients with type 2 diabetes and associated with endothelial dysfunction.
Topics: Aged; Arginase; Arginine; Biomarkers; Case-Control Studies; Citrulline; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Female; Forearm; Humans; Male; Middle Aged; Nitric Oxide Synthase; Ornithine; Up-Regulation; Vasodilation | 2016 |
Roles of export genes cgmA and lysE for the production of L-arginine and L-citrulline by Corynebacterium glutamicum.
Topics: Amino Acid Transport Systems, Basic; Arginine; Bacterial Proteins; Citrulline; Corynebacterium glutamicum; Gene Deletion; Gene Expression | 2016 |
Two weeks of watermelon juice supplementation improves nitric oxide bioavailability but not endurance exercise performance in humans.
Topics: Arginine; Arterial Pressure; Blood Glucose; Citrulline; Citrullus; Dietary Supplements; Fruit and Vegetable Juices; Heart Rate; Humans; Lactic Acid; Male; Malus; Nitric Oxide; Nitrites; Oxygen Consumption; Physical Endurance; Pulmonary Gas Exchange; Young Adult | 2016 |
Extensive Citrullination Promotes Immunogenicity of HSP90 through Protein Unfolding and Exposure of Cryptic Epitopes.
Topics: Arginine; Autoantibodies; Citrulline; Enzyme-Linked Immunosorbent Assay; Epitopes; HSP90 Heat-Shock Proteins; Humans; Hydrolases; Mass Spectrometry; Molecular Dynamics Simulation; Peptides; Protein Isoforms; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Unfolding; Protein-Arginine Deiminases | 2016 |
Altered brain arginine metabolism in schizophrenia.
Topics: Agmatine; Arginase; Arginine; Autopsy; Blotting, Western; Brain; Case-Control Studies; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citrulline; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Mass Spectrometry; Middle Aged; Nitric Oxide Synthase Type III; Ornithine; Regression Analysis; Schizophrenia | 2016 |
PADI4 has genetic susceptibility to gastric carcinoma and upregulates CXCR2, KRT14 and TNF-α expression levels.
Topics: Apoptosis; Arginine; Carcinogenesis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Citrulline; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Genotyping Techniques; Humans; Keratin-14; Neovascularization, Pathologic; Polymorphism, Single Nucleotide; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Receptors, Interleukin-8B; RNA Interference; RNA, Small Interfering; Signal Transduction; Stomach Neoplasms; Tumor Necrosis Factor-alpha; Up-Regulation | 2016 |
l-citrulline prevents asymmetric dimethylarginine-mediated reductions in nitric oxide and nitrosative stress in primary human airway epithelial cells.
Topics: Adult; Arginine; Asthma; Citrulline; Epithelial Cells; Female; Humans; Hydrogen Peroxide; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Nitrosative Stress; Oxidation-Reduction; Respiratory Function Tests; Respiratory Mucosa; Young Adult | 2017 |
Bacterial toxins activation of abbreviated urea cycle in porcine cerebral vascular smooth muscle cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Argininosuccinate Synthase; Bacterial Toxins; Cerebral Arteries; Citrulline; Female; Lipopolysaccharides; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Synthase Type II; Swine; Teichoic Acids; Urea; Vasoconstrictor Agents | 2016 |
Cl-Amidine Prevents Histone 3 Citrullination and Neutrophil Extracellular Trap Formation, and Improves Survival in a Murine Sepsis Model.
Topics: Animals; Arginine; Cecum; Cell Movement; Cells, Cultured; Citrulline; Disease Models, Animal; Extracellular Traps; Histones; Humans; Hydrolases; Male; Mice; Mice, Inbred C57BL; Neutrophils; Ornithine; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Sepsis | 2017 |
Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting antidepressants.
Topics: Adult; Arginine; Citrulline; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Indoleacetic Acids; Infusions, Intravenous; Ketamine; Male; Metabolomics; Methionine; Middle Aged; Ornithine; Phenotype; Phospholipids; Tryptophan; Urea | 2016 |
Co-application of canavanine and irradiation uncouples anticancer potential of arginine deprivation from citrulline availability.
Topics: Apoptosis; Arginine; Argininosuccinate Synthase; Canavanine; Cell Cycle; Cell Line, Tumor; Citrulline; Colorectal Neoplasms; DNA Methylation; Gene Expression; Humans; Intestinal Mucosa; Radiation Tolerance; Radiation, Ionizing; Spheroids, Cellular; Tumor Cells, Cultured | 2016 |
A propeptide-independent protease from Tannerella sp.6_1_58FAA_CT1 displays trypsin-like specificity.
Topics: Adhesins, Bacterial; Animals; Arginine; Bacteroidetes; Binding Sites; Cattle; Citrulline; Cysteine Endopeptidases; Cysteine Proteases; Gingipain Cysteine Endopeptidases; Kinetics; Lysine; Models, Molecular; Recombinant Proteins; Substrate Specificity; Swine; Tannerella forsythia; Trypsin | 2017 |
The increased ability to present citrullinated peptides is not unique to HLA-SE molecules: arginine-to-citrulline conversion also enhances peptide affinity for HLA-DQ molecules.
Topics: Antigen Presentation; Arginine; Arthritis, Rheumatoid; Autoantigens; Cell Line; Citrulline; HLA-DQ Antigens; Humans; Models, Molecular; Peptides, Cyclic | 2016 |
Decreased Rate of Plasma Arginine Appearance in Murine Malaria May Explain Hypoargininemia in Children With Cerebral Malaria.
Topics: Animals; Arginase; Arginine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Citrulline; Female; Humans; Infant; Malaria; Malaria, Cerebral; Malawi; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Ornithine; Plasma; Plasmodium berghei; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |
Supramolecular Chemistry-Assisted Electrochemical Method for the Assay of Endogenous Peptidylarginine Deiminases Activities.
Topics: Arginine; Citrulline; Electrochemical Techniques; Humans; Hydrolases; Oligopeptides; Protein-Arginine Deiminases | 2017 |
Predicting Citrullination Sites in Protein Sequences Using mRMR Method and Random Forest Algorithm.
Topics: Algorithms; Amino Acid Sequence; Arginine; Binding Sites; Citrulline; Humans; Hydrolases; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Support Vector Machine | 2017 |
24-Hour protein, arginine and citrulline metabolism in fed critically ill children - A stable isotope tracer study.
Topics: Arginine; Carbon Isotopes; Child; Child, Preschool; Circadian Rhythm; Citrulline; Critical Illness; Dietary Proteins; Enteral Nutrition; Humans; Infant; Intensive Care Units; Leucine; Phenylalanine; Tyrosine | 2017 |
Correlation between plasma levels of arginine and citrulline in preterm and full-term neonates: Therapeutical implications.
Topics: Arginine; Citrulline; Cohort Studies; Electrophoresis, Capillary; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Infant, Premature, Diseases; Male; Nitric Oxide; Spectrometry, Fluorescence | 2017 |
Levels of l-arginine and l-citrulline in patients with erectile dysfunction of different etiology.
Topics: Adult; Arginine; Citrulline; Erectile Dysfunction; Humans; Male; Middle Aged; Penile Erection; Severity of Illness Index; Ultrasonography, Doppler, Color | 2017 |
Metabolic profiling of presymptomatic Huntington's disease sheep reveals novel biomarkers.
Topics: Amino Acids, Branched-Chain; Animals; Animals, Genetically Modified; Area Under Curve; Arginine; Biomarkers; Citrulline; Genotype; Huntington Disease; Logistic Models; Metabolomics; ROC Curve; Sheep | 2017 |
Drastic decrease of global l-arginine bioavailability during orthotopic liver transplantation: A matter of ATP deficiency of the graft?
Topics: Adenosine Triphosphate; Arginine; Biological Availability; Citrulline; Humans; Liver Transplantation; Ornithine | 2018 |
Further studies of the effects of aging on arginine metabolites in the rat vestibular nucleus and cerebellum.
Topics: Aging; Animals; Arginine; Cerebellum; Citrulline; Glutamic Acid; Male; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley; Vestibular Nuclei | 2017 |
Lowering relative humidity level increases epidermal protein deimination and drives human filaggrin breakdown.
Topics: Adult; Arginine; Cell Differentiation; Citrulline; Climate; Cross-Linking Reagents; Dermatitis, Atopic; Epidermis; Female; Filaggrin Proteins; Fluorescent Dyes; Humans; Humidity; Hydrogen-Ion Concentration; Hydrolases; Intermediate Filament Proteins; Keratinocytes; Keratins; Microscopy, Electron, Transmission; Middle Aged; Protein-Arginine Deiminases; Skin; Transglutaminases | 2017 |
The nitric oxide synthase 2 pathway is targeted by both pro- and anti-inflammatory treatments in the immature human intestine.
Topics: Anti-Inflammatory Agents; Arginine; Citrulline; Epidermal Growth Factor; Fetal Research; Gastrointestinal Agents; Humans; Ileum; Indomethacin; Nitric Oxide Synthase Type II; Organ Culture Techniques; Signal Transduction | 2017 |
Plasma Arginine/Asymmetric Dimethylarginine Ratio and Incidence of Cardiovascular Events: A Case-Cohort Study.
Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Chromatography, Liquid; Citrulline; Cohort Studies; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; omega-N-Methylarginine; Ornithine; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Tandem Mass Spectrometry | 2017 |
Expression of peptidylarginine deiminase 4 in an alkali injury model of retinal gliosis.
Topics: Animals; Arginine; Burns, Chemical; Citrulline; Eye Burns; Female; Gliosis; Hydrolases; Male; Mice; Protein-Arginine Deiminase Type 4; Retina; Retinal Diseases; Sodium Hydroxide | 2017 |
A novel mass spectrometry-based method for simultaneous determination of asymmetric and symmetric dimethylarginine, l-arginine and l-citrulline optimized for LC-MS-TOF and LC-MS/MS.
Topics: Arginine; Chromatography, Liquid; Citrulline; Humans; Limit of Detection; Linear Models; Nitric Oxide; Reproducibility of Results; Tandem Mass Spectrometry | 2017 |
Theoretical insights into the protonation states of active site cysteine and citrullination mechanism of Porphyromonas gingivalis peptidylarginine deiminase.
Topics: Amino Acid Motifs; Arginine; Aspartic Acid; Bacterial Proteins; Binding Sites; Catalytic Domain; Citrulline; Crystallography, X-Ray; Cysteine; Histidine; Hydrolases; Hydrolysis; Molecular Dynamics Simulation; Porphyromonas gingivalis; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein-Arginine Deiminases; Protons; Quantum Theory; Substrate Specificity; Thermodynamics | 2017 |
The intestinal-renal axis for arginine synthesis is present and functional in the neonatal pig.
Topics: Animals; Animals, Domestic; Animals, Newborn; Arginine; Cells, Cultured; Citrulline; Intestinal Mucosa; Kidney; Metabolic Networks and Pathways; Organ Culture Techniques; Premature Birth; Sus scrofa; Swine | 2017 |
Plasma l-citrulline concentrations in l-arginine-supplemented healthy dogs.
Topics: Animals; Arginine; Blood Pressure; Citrulline; Dogs; Female; Male; Nitric Oxide | 2017 |
Alterations in Circulating Amino Acid Metabolite Ratio Associated with Arginase Activity Are Potential Indicators of Metabolic Syndrome: The Korean Genome and Epidemiology Study.
Topics: Adult; Aged; Alanine Transaminase; Amino Acids; Arginase; Arginine; Asian People; Aspartate Aminotransferases; Cholesterol; Citrulline; Cross-Sectional Studies; Epidemiologic Studies; Female; Follow-Up Studies; Humans; Life Style; Male; Metabolic Syndrome; Middle Aged; Ornithine; Proline; Prospective Studies; Republic of Korea; Risk Factors; Surveys and Questionnaires; Triglycerides | 2017 |
Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.
Topics: Alaska; Alaskan Natives; Alleles; Arginine; Arthritis, Rheumatoid; Autoantibodies; Canada; Case-Control Studies; CD4-Positive T-Lymphocytes; Citrulline; Female; Flow Cytometry; Genetic Predisposition to Disease; Genotype; HLA-DRB1 Chains; Humans; Indians, North American; Male; Peptides, Cyclic; Polymorphism, Genetic; Risk Factors; Vimentin | 2017 |
Decreased serum L-arginine and L-citrulline levels in major depression.
Topics: Adolescent; Adult; Arginine; Cardiovascular Diseases; Citrulline; Depressive Disorder, Major; Female; Humans; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Reference Values; Risk Factors; Young Adult | 2017 |
Joint inflammation related citrullination of functional arginines in extracellular proteins.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arginine; Arthritis; Chronic Disease; Citrullination; Citrulline; Extracellular Matrix Proteins; Extracellular Space; Humans; Models, Molecular; Protein Conformation; Protein Interaction Domains and Motifs; Structure-Activity Relationship; Synovial Fluid | 2017 |
Major surgery diminishes systemic arginine availability and suppresses nitric oxide response to feeding in patients with early stage breast cancer.
Topics: Adult; Arginine; Breast Neoplasms; Citrulline; Female; Genetic Predisposition to Disease; Glutamine; Humans; Mastectomy; Metabolic Clearance Rate; Middle Aged; Nitric Oxide; Postoperative Complications; Postprandial Period | 2018 |
The utility of arginine-citrulline stable isotope tracer infusion technique in the assessment of nitric oxide production in MELAS syndrome.
Topics: Arginine; Citrulline; Humans; Isotopes; MELAS Syndrome; Nitric Oxide | 2018 |
Decreased nitric oxide serum level after pituitary adenoma resection.
Topics: Adenoma; Arginine; Citrulline; Humans; Nitric Oxide; Pituitary Neoplasms | 2020 |
Plasma biomarker discovery for early chronic kidney disease diagnosis based on chemometric approaches using LC-QTOF targeted metabolomics data.
Topics: Adolescent; Age Factors; Arginine; Biomarkers; Child; Child, Preschool; Chromatography, High Pressure Liquid; Citrulline; Creatinine; Early Diagnosis; Female; Glomerular Filtration Rate; Humans; Male; Metabolic Networks and Pathways; Metabolomics; Multivariate Analysis; Renal Insufficiency, Chronic; S-Adenosylmethionine; Sex Factors; Tandem Mass Spectrometry | 2018 |
On the role of salt formation and structural similarity of co-formers in co-amorphous drug delivery systems.
Topics: Adjuvants, Pharmaceutic; Arginine; Citrulline; Drug Delivery Systems; Drug Stability; Molecular Structure; Pharmaceutical Preparations; Salts; Solubility; Technology, Pharmaceutical | 2018 |
The IN-PANCIA Study: Clinical Evaluation of Gastrointestinal Dysfunction and Failure, Multiple Organ Failure, and Levels of Citrulline in Critically Ill Patients.
Topics: Aged; Arginine; Biomarkers; Citrulline; Critical Illness; Female; Gastrointestinal Diseases; Glutamine; Humans; Intensive Care Units; Intra-Abdominal Hypertension; Male; Middle Aged; Multiple Organ Failure; Organ Dysfunction Scores; Prospective Studies | 2020 |
[Production of L-citrulline by a recombinant Corynebacterium crenatum SYPA 5-5 whole-cell biocatalyst].
Topics: Arginine; Citrulline; Corynebacterium; Hydrolases; Industrial Microbiology | 2017 |
Experience of correcting endothelial dysfunction in children-residents of radioactively contaminated areas by nitric oxide potential donator citrulline.
Topics: Arginine; Bronchial Spasm; Cardiovascular Diseases; Chernobyl Nuclear Accident; Child; Citrulline; Endothelium, Vascular; Female; Humans; Immunity, Cellular; Immunity, Humoral; Lipid Peroxidation; Malates; Male; Nitric Oxide; Nitric Oxide Donors; Nitrites; Radiation Dosage; Radiation Exposure; Radioactive Pollutants; Rural Population; Survivors; T-Lymphocytes; Ukraine; Urban Population | 2017 |
A pilot study of a non-invasive oral nitrate stable isotopic method suggests that arginine and citrulline supplementation increases whole-body NO production in Tanzanian children with sickle cell disease.
Topics: Administration, Oral; Anemia, Sickle Cell; Arginine; Child; Citrulline; Dietary Supplements; Female; Humans; Male; Nitrates; Nitric Oxide; Nitrogen Isotopes; Pilot Projects; Tanzania | 2018 |
Global arginine bioavailability ratio is decreased in patients with major depressive disorder.
Topics: Adult; Aged; Arginine; Biological Availability; Citrulline; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Nitric Oxide; Ornithine; Oxidative Stress; Surveys and Questionnaires; Young Adult | 2018 |
Theoretical studies of the second step of the nitric oxide synthase reaction: Electron tunneling prevents uncoupling.
Topics: Animals; Arginine; Biocatalysis; Biopterins; Catalytic Domain; Citrulline; Conserved Sequence; Databases, Protein; Electron Transport; Humans; Hydrogen Bonding; Models, Molecular; NADP; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidation-Reduction; Protons; Quantum Theory; Thermodynamics | 2018 |
Administration of L-arginine plus L-citrulline or L-citrulline alone successfully retarded endothelial senescence.
Topics: Animals; Arginine; Cellular Senescence; Citrulline; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Rats; Rats, Zucker | 2018 |
Biochemical markers and neuropsychological functioning in distal urea cycle disorders.
Topics: Adolescent; Adult; Ammonia; Arginine; Argininosuccinic Aciduria; Biomarkers; Child; Child, Preschool; Citrulline; Citrullinemia; Female; Glutamine; Humans; Hyperargininemia; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; Young Adult | 2018 |
8-year retrospective analysis of intravenous arginine therapy for acute metabolic strokes in pediatric mitochondrial disease.
Topics: Adolescent; Adult; Arginine; Brain; Child; Child, Preschool; Citrulline; DNA, Mitochondrial; Female; Humans; Infant; Infusions, Intravenous; Magnetic Resonance Imaging; Male; Mitochondria; Mitochondrial Diseases; Nitric Oxide; Prospective Studies; Retrospective Studies; Stroke; Treatment Outcome; Young Adult | 2018 |
Accumulation of Citrulline by Microbial Arginine Metabolism during Alcoholic Fermentation of Soy Sauce.
Topics: Arginine; Carcinogens; Citrulline; Ethanol; Fermentation; Pediococcus acidilactici; Soy Foods; Staphylococcus | 2018 |
Effects of glucocorticoids on serum amino acid levels during cardiac surgery in children.
Topics: Adolescent; Amino Acids; Arginine; Cardiac Surgical Procedures; Child; Child, Preschool; Citrulline; Female; Glucocorticoids; Glutamine; Heart Defects, Congenital; Humans; Hydrocortisone; Infant; Intensive Care Units, Pediatric; Male; Nitric Oxide; Prospective Studies | 2018 |
Kidney Mass Reduction Leads to l-Arginine Metabolism-Dependent Blood Pressure Increase in Mice.
Topics: Animals; Arginase; Arginine; Blood Pressure; Citrulline; Female; Kidney; Male; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Nitric Oxide; Organ Size | 2018 |
Ready-to-use food supplement, with or without arginine and citrulline, with daily chloroquine in Tanzanian children with sickle-cell disease: a double-blind, random order crossover trial.
Topics: Anemia, Sickle Cell; Arginine; Child; Chloroquine; Citrulline; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Humans; Male; Tanzania | 2018 |
Plasma citrulline levels are increased in patients with multiple sclerosis.
Topics: Adult; Aged; Arginine; Citrulline; Disability Evaluation; Female; Glutamine; Humans; Immunologic Factors; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Myelin Basic Protein; Nitric Oxide; Statistics, Nonparametric | 2018 |
The cyanobacterial ornithine-ammonia cycle involves an arginine dihydrolase.
Topics: Ammonia; Arginine; Bacterial Proteins; Biomass; Carbon Dioxide; Citrulline; Cyanobacteria; Hydrolases; Mutation; Nitrogen; Nitrogen Isotopes; Ornithine; Oscillometry; Polyamines; Synechocystis; Urea | 2018 |
Alterations in plasma L-arginine and methylarginines in heart failure and after heart transplantation.
Topics: Arginine; Biomarkers; Citrulline; Endothelium, Vascular; Female; Heart Failure; Heart Transplantation; Hemodynamics; Humans; Male; Middle Aged; Nitric Oxide; Ornithine; Prospective Studies; Time Factors; Treatment Outcome | 2018 |
[Characterization of arginine utilization strains from fermented grains and evaluation of their contribution to citrulline accumulation in Chinese Luzhou-flavor spirits].
Topics: Arginine; Bacillus amyloliquefaciens; Citrulline; Edible Grain; Fermentation; Lactococcus; Pediococcus acidilactici; Staphylococcus; Urethane; Wine | 2016 |
Pentraxins CRP-I and CRP-II are post-translationally deiminated and differ in tissue specificity in cod (Gadus morhua L.) ontogeny.
Topics: Animals; Arginine; C-Reactive Protein; Citrulline; Fish Proteins; Gadus morhua; Humans; Mucous Membrane; Nerve Tissue; Organ Specificity; Protein Isoforms; Protein Processing, Post-Translational | 2018 |
Giardia lamblia: identification of molecules that contribute to direct mast cell activation.
Topics: Animals; Arginine; Cell Extracts; Cell Line; Citrulline; Giardia lamblia; Giardiasis; Hydrolases; Interleukin-6; Mast Cells; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Toll-Like Receptor 2; Toll-Like Receptor 4; Trophozoites; Tumor Necrosis Factor-alpha | 2018 |
Replacing voltage sensor arginines with citrulline provides mechanistic insight into charge versus shape.
Topics: Amino Acid Substitution; Animals; Arginine; Citrulline; Ion Channel Gating; Membrane Potentials; Mice; Protein Domains; Shaker Superfamily of Potassium Channels; Static Electricity; Xenopus | 2018 |
The Citrulline Recycling Pathway Sustains Cardiovascular Function in Arginine-Depleted Healthy Mice, but Cannot Sustain Nitric Oxide Production during Endotoxin Challenge.
Topics: Animals; Arginine; Argininosuccinate Synthase; Citrulline; Endotoxins; Gene Expression Regulation, Enzymologic; Hydrolases; Isotope Labeling; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Nitric Oxide; Polyethylene Glycols; Vasomotor System | 2018 |
Post-translational protein deimination in cod (Gadus morhua L.) ontogeny novel roles in tissue remodelling and mucosal immune defences?
Topics: Animals; Arginine; Citrulline; Fish Proteins; Gadus morhua; Imines; Immunity, Mucosal; Larva; Mucous Membrane; Phylogeny; Protein Processing, Post-Translational; Protein-Arginine Deiminases | 2018 |
Progesterone-associated arginine decline at luteal phase of menstrual cycle and associations with related amino acids and nuclear factor kB activation.
Topics: Adult; Amino Acids; Arginine; Citrulline; Female; Follicular Phase; Healthy Volunteers; Humans; Leukocytes, Mononuclear; Luteal Phase; NF-kappa B p50 Subunit; Ornithine; Progesterone; Putrescine; Reference Values; Spermidine; Spermine; Transcription Factor RelA | 2018 |
Plasma citrulline is a sensitive safety biomarker for small intestinal injury in rats.
Topics: Animals; Antineoplastic Agents, Phytogenic; Arginine; Biomarkers; Camptothecin; Citrulline; Down-Regulation; Ileum; Intestinal Diseases; Irinotecan; Jejunum; Male; Metabolomics; Rats, Sprague-Dawley; Time Factors | 2018 |
Thermostability and Specific-Activity Enhancement of an Arginine Deiminase from Enterococcus faecalis SK23.001 via Semirational Design for l-Citrulline Production.
Topics: Arginine; Bacterial Proteins; Citrulline; Enterococcus faecalis; Enzyme Stability; Hydrolases; Kinetics; Protein Engineering; Substrate Specificity | 2018 |
Prematurity reduces citrulline-arginine-nitric oxide production and precedes the onset of necrotizing enterocolitis in piglets.
Topics: Animals; Arginine; Citrulline; Enterocolitis, Necrotizing; Fetal Development; Intestinal Mucosa; Nitric Oxide; Swine | 2018 |
Changes in arginine are inversely associated with type 2 diabetes: A case-cohort study in the PREDIMED trial.
Topics: Aged; Aged, 80 and over; Arginine; Case-Control Studies; Citrulline; Cohort Studies; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Diet, Mediterranean; Female; Humans; Incidence; Insulin Resistance; Male; Middle Aged; omega-N-Methylarginine; Ornithine; Risk Factors | 2019 |
Ex Vivo Enteroids Recapitulate In Vivo Citrulline Production in Mice.
Topics: Animals; Arginine; Citrulline; Disease Models, Animal; Intestines; Liver; Male; Mice; Mice, Inbred ICR; Mice, Mutant Strains; Mutation; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Tissue Culture Techniques; Urea | 2018 |
Watermelon and l-arginine consumption improve serum lipid profile and reduce inflammation and oxidative stress by altering gene expression in rats fed an atherogenic diet.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Atherosclerosis; C-Reactive Protein; Cardiovascular Diseases; Citrulline; Citrullus; Diet, Atherogenic; Dietary Supplements; Gene Expression; Gene Expression Regulation; Hydroxymethylglutaryl CoA Reductases; Inflammation; Lipid Metabolism; Lipids; Liver; Male; NF-kappa B; Oxidative Stress; Plant Preparations; Rats, Sprague-Dawley; Sterol Regulatory Element Binding Protein 2 | 2018 |
Citrulline Generation Test: What Does It Measure?
Topics: Animals; Arginine; Citrulline; Dipeptides; Enteral Nutrition; Female; Gastrointestinal Tract; Glutamine; Infusions, Intravenous; Kidney; Male; Models, Animal; Nitrogen Isotopes; Parenteral Nutrition; Swine | 2019 |
Simultaneous analysis of acetylcarnitine, proline, hydroxyproline, citrulline, and arginine as potential plasma biomarkers to evaluate NSAIDs-induced gastric injury by liquid chromatography-tandem mass spectrometry.
Topics: Acetylcarnitine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Biomarkers; Chromatography, Liquid; Citrulline; Diclofenac; Dogs; Gastrointestinal Diseases; Hydroxyproline; Limit of Detection; Male; Proline; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry | 2019 |
Pharmacological activation of dimethylarginine dimethylaminohydrolase (DDAH) activity by inorganic nitrate and DDAH inhibition by N
Topics: Amidohydrolases; Animals; Arginine; Citrulline; Liver; Nitrates; Rats; Recombinant Proteins | 2019 |
The Effect of Branched-Chain Amino Acids, Citrulline, and Arginine on High-Intensity Interval Performance in Young Swimmers.
Topics: Adolescent; Amino Acids, Branched-Chain; Arginine; Athletes; Citrulline; Female; Humans; Male; Physical Exertion; Sports; Swimming | 2018 |
l-Arginine metabolism before and after 10 weeks of antipsychotic treatment in first-episode psychotic patients.
Topics: Agmatine; Antipsychotic Agents; Arginine; Case-Control Studies; Citrulline; Female; Humans; Male; Olanzapine; Ornithine; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Risperidone; Young Adult | 2019 |
The iridoid loganic acid and anthocyanins from the cornelian cherry (Cornus mas L.) fruit increase the plasma l-arginine/ADMA ratio and decrease levels of ADMA in rabbits fed a high-cholesterol diet.
Topics: Amidohydrolases; Animals; Anthocyanins; Arginine; Atherosclerosis; Cholesterol, Dietary; Citrulline; Cornus; Dimethylamines; Fruit; Iridoids; Liver; Male; Nitric Oxide Synthase Type III; Rabbits | 2019 |
L-Arginine and L-Citrulline Supplementation Have Different Programming Effect on Regulatory T-Cells Function of Infantile Rats.
Topics: Animals; Animals, Newborn; Arginine; Citrulline; Dietary Supplements; Female; Forkhead Transcription Factors; Gene Expression Regulation; Interferon-gamma; Interleukin-10; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Smad7 Protein; T-Lymphocytes, Regulatory; Th1 Cells | 2018 |
Low CO2 induces urea cycle intermediate accumulation in Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Arginine; Biosynthetic Pathways; Carbon Dioxide; Citrulline; Gene Expression Regulation, Plant; Genes, Plant; Light; Models, Biological; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles; RNA, Plant; Stress, Physiological; Sucrose; Urea | 2019 |
l-Arginine Synthesis from l-Citrulline in Myeloid Cells Drives Host Defense against Mycobacteria In Vivo.
Topics: Animals; Arginine; Citrulline; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mycobacterium Infections; Myeloid Cells; Respiratory Tract Infections | 2019 |
Citrulline as a novel adjuvant candidate for vaccines.
Topics: Adjuvants, Immunologic; Alum Compounds; Amyloid beta-Peptides; Animals; Arginine; Citrulline; Female; Hemagglutinin Glycoproteins, Influenza Virus; Immunization; Mice; Peptides; Vaccines; Vaccines, Inactivated | 2019 |
Plasma citrulline, arginine, nitric oxide, and blood ammonia levels in neonatal calves with acute diarrhea.
Topics: Ammonia; Animals; Animals, Newborn; Arginine; Case-Control Studies; Cattle; Cattle Diseases; Citrulline; Dehydration; Diarrhea; Nitric Oxide; Systemic Inflammatory Response Syndrome | 2019 |
LC-QQQ-MS routine analysis method for new biomarker quantification in plasma aimed at early chronic kidney disease diagnosis.
Topics: Arginine; Biomarkers; Child; Child, Preschool; Chromatography, Liquid; Citrulline; Creatinine; Early Diagnosis; Female; Glomerular Filtration Rate; Humans; Male; Metabolomics; Plasma; Renal Insufficiency, Chronic; S-Adenosylmethionine; Tandem Mass Spectrometry | 2019 |
Citrulline protects mice from experimental cerebral malaria by ameliorating hypoargininemia, urea cycle changes and vascular leak.
Topics: Animals; Arginase; Arginine; Blood-Brain Barrier; Citrulline; Dietary Supplements; Disease Models, Animal; Free Radical Scavengers; Humans; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Nitric Oxide; Plasmodium berghei; Superoxides; Urea | 2019 |
Toward a Scientific Nutritional Supplement Combination for Prostatism and Erectile Dysfunction I: From Known Pharmacology to Clinical Testing.
Topics: Arginine; Cholecalciferol; Citrulline; Clinical Trials as Topic; Dietary Supplements; Erectile Dysfunction; Humans; Male; Meta-Analysis as Topic; Middle Aged; Panax; Pilot Projects; Plant Extracts; Prostatism; Sitosterols; Urination | 2019 |
Peptidylarginine Deiminase Inhibitor Cl-Amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis.
Topics: Arginine; Autophagy; Cell Differentiation; Cells, Cultured; Citrulline; Epidermis; Humans; Keratinocytes; Microscopy, Electron, Transmission; Ornithine; Primary Cell Culture; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 1; Protein-Arginine Deiminase Type 3; Recombinant Proteins | 2019 |
Nitric oxide synthase-mediated early nitric oxide burst alleviates water stress-induced oxidative damage in ammonium-supplied rice roots.
Topics: Ammonium Compounds; Antioxidants; Arginine; Citrulline; Dehydration; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oryza; Oxidation-Reduction; Plant Proteins; Plant Roots | 2019 |
A simple dual-inducible CRISPR interference system for multiple gene targeting in Corynebacterium glutamicum.
Topics: Arginine; Argininosuccinate Lyase; Bacterial Proteins; Base Pairing; Base Sequence; Citrulline; Corynebacterium glutamicum; CRISPR-Associated Protein 9; CRISPR-Cas Systems; Gene Expression Regulation, Bacterial; Gene Targeting; Glucose-6-Phosphate Isomerase; Isopropyl Thiogalactoside; Plasmids; RNA, Guide, Kinetoplastida; Tetracyclines | 2019 |
Lack of relationship between fasting plasma citrulline and glucose absorption: do not underestimate the role of the failing kidney!
Topics: Arginine; Citrulline; Critical Illness; Fasting; Glucose; Humans; Kidney | 2019 |
Asymmetric dimethylation and citrullination of proteinic arginine and homoarginine synthesis in human Helicobacter pylori infection.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Citrullination; Citrulline; Female; Gas Chromatography-Mass Spectrometry; Helicobacter Infections; Helicobacter pylori; Homoarginine; Humans; Lysine; Male; Methylation; Middle Aged; Nitric Oxide; Ornithine | 2019 |
Effects of Arginine Deimination and Citrulline Side-Chain Length on Peptide Secondary Structure Formation.
Topics: Arginine; Citrulline; Molecular Conformation; Peptide Biosynthesis; Peptides; Thermodynamics | 2019 |
Exogenous l-ARGININE does not stimulate production OF NO or cGMP within the rat corporal smooth muscle cells in culture.
Topics: Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Male; Muscle, Smooth; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Penis; Phosphodiesterase 5 Inhibitors; Rats, Sprague-Dawley | 2019 |
Deiminated proteins in extracellular vesicles and plasma of nurse shark (Ginglymostoma cirratum) - Novel insights into shark immunity.
Topics: Animals; Arginine; Citrullination; Citrulline; Extracellular Vesicles; Fish Proteins; Protein-Arginine Deiminases; Sharks | 2019 |
Ruminal microbes of adult steers do not degrade extracellular L-citrulline and have a limited ability to metabolize extracellular L-glutamate1,2.
Topics: Amino Acids; Ammonia; Animals; Arginine; Bacteria; Cattle; Citrulline; Glutamic Acid; Glutamine; Male; Ornithine; Proline; Rumen | 2019 |
Establishment of reference values for the lysine acetylation marker N
Topics: Adolescent; Adult; Arginine; Biomarkers; Cardiovascular Diseases; Carnitine; Chromatography, Liquid; Citrulline; Creatinine; Female; Homoarginine; Humans; Lysine; Male; Middle Aged; Ornithine; Reference Values; Renal Insufficiency, Chronic; Tandem Mass Spectrometry; Young Adult | 2019 |
Metabolites of the Nitric Oxide (NO) Pathway Are Altered and Indicative of Reduced NO and Arginine Bioavailability in Patients with Cardiometabolic Diseases Complicated with Chronic Wounds of Lower Extremities: Targeted Metabolomics Approach (LC-MS/MS).
Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Chemokines; Citrulline; Cytokines; Female; Growth Hormone; Humans; Lower Extremity; Male; Metabolomics; Middle Aged; Nitric Oxide; Wounds and Injuries | 2019 |
A synthetic metabolic network for physicochemical homeostasis.
Topics: Adenosine Triphosphate; Arginine; Artificial Cells; Carrier Proteins; Citrulline; Energy Metabolism; Hydrolases; Lactococcus lactis; Metabolic Networks and Pathways; Ornithine; Ornithine Carbamoyltransferase; Phosphotransferases (Carboxyl Group Acceptor) | 2019 |
Targeted metabolomic analysis of nitric oxide/L-arginine pathway metabolites in dementia: association with pathology, severity, and structural brain changes.
Topics: Arginine; Biomarkers; Brain; Citrulline; Dementia; Female; Humans; Male; Metabolomics; Middle Aged; Nitric Oxide; Signal Transduction | 2019 |
Aspergillus nidulans thermostable arginine deiminase-Dextran conjugates with enhanced molecular stability, proteolytic resistance, pharmacokinetic properties and anticancer activity.
Topics: Animals; Antineoplastic Agents; Arginine; Aspergillus nidulans; Cell Line, Tumor; Cell Proliferation; Citrulline; Dextrans; Enzyme Stability; Humans; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Mice; Molecular Weight; Protein Multimerization; Proteolysis; Temperature | 2019 |
Post-Translational Deimination of Immunological and Metabolic Protein Markers in Plasma and Extracellular Vesicles of Naked Mole-Rat (
Topics: Animals; Arginine; Biomarkers; Blood Proteins; Citrulline; Extracellular Vesicles; Gene Expression Regulation; Genome; Humans; Immunity; Longevity; MicroRNAs; Mole Rats; Plasma; Protein Interaction Maps; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Proteomics | 2019 |
Haplotype Networking of GWAS Hits for Citrulline Variation Associated with the Domestication of Watermelon.
Topics: Acetolactate Synthase; Arginine; Citrulline; Citrullus; Domestication; Ferrochelatase; Gene Frequency; Gene Ontology; Genes, Plant; Genome-Wide Association Study; Genome, Plant; Haplotypes; Nitric Oxide; Osmoregulation; Phenotype; Phylogeny; Polymorphism, Single Nucleotide | 2019 |
Pravastatin induces NO synthesis by enhancing microsomal arginine uptake in healthy and preeclamptic placentas.
Topics: Adult; Arginine; Benzoquinones; Case-Control Studies; Citrulline; Enzyme Inhibitors; Female; Humans; Lactams, Macrocyclic; Microsomes; Nitric Oxide Synthase Type III; Placenta; Pravastatin; Pre-Eclampsia; Pregnancy | 2019 |
Developmental changes in the utilization of citrulline by neonatal pigs.
Topics: Aging; Animals; Animals, Newborn; Arginine; Citrulline; Female; Kidney; Male; Swine | 2020 |
Broad-Spectrum Amino Acid Transporters ClAAP3 and ClAAP6 Expressed in Watermelon Fruits.
Topics: Amino Acid Transport Systems; Arginine; Citrulline; Citrullus; Fruit; Nicotiana; Plant Proteins; Plants, Genetically Modified; Substrate Specificity | 2019 |
Supplementation of arginine, ornithine and citrulline in rainbow trout (Oncorhynchus mykiss): Effects on growth, amino acid levels in plasma and gene expression responses in liver tissue.
Topics: Amino Acids; Animals; Arginine; Citrulline; Dietary Supplements; Liver; Oncorhynchus mykiss; Ornithine | 2020 |
Metabolic studies reveal that ruminal microbes of adult steers do not degrade rumen-protected or unprotected L-citrulline.
Topics: Ammonia; Animal Feed; Animals; Arginine; Cattle; Citrulline; Diet; Digestion; Edible Grain; Fermentation; Gastrointestinal Microbiome; Glutamic Acid; Glutamine; Male; Rumen | 2020 |
CRISPR-Cpf1-Assisted Engineering of Corynebacterium glutamicum SNK118 for Enhanced L-Ornithine Production by NADP-Dependent Glyceraldehyde-3-Phosphate Dehydrogenase and NADH-Dependent Glutamate Dehydrogenase.
Topics: Arginine; Bioreactors; Citrulline; Corynebacterium glutamicum; CRISPR-Cas Systems; Escherichia coli; Fermentation; Genome, Bacterial; Glucose; Glutamate Synthase (NADH); Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Industrial Microbiology; Metabolic Engineering; NADP; Ornithine; Plasmids; Recombinant Proteins; Transcription, Genetic | 2020 |
Citrullination mediated by PPAD constrains biofilm formation in P. gingivalis strain 381.
Topics: Adhesins, Bacterial; Arginine; Biofilms; Citrullination; Citrulline; Gene Deletion; Porphyromonas gingivalis; Protein-Arginine Deiminases | 2019 |
Prevention of vaginal dryness in perimenopausal women. Supplementation with Lady Prelox®.
Topics: Adult; Arginine; Citrulline; Dietary Supplements; Female; Flavonoids; Humans; Middle Aged; Pilot Projects; Postmenopause; Premenopause; Quality of Life; Sexual Dysfunction, Physiological; Surveys and Questionnaires; Vagina | 2019 |
Combined l-citrulline and tetrahydrobiopterin therapy improves NO signaling and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs.
Topics: Animals; Animals, Newborn; Arginine; Biopterins; Citrulline; Hypertension, Pulmonary; Hypoxia; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Artery; Signal Transduction; Swine; Vascular Resistance | 2020 |
[Prevention of the progression of atherosclerosis and aging through nitric oxide (NO)].
Topics: Aging; Animals; Arginine; Atherosclerosis; Citrulline; Humans; Nitric Oxide; Nitric Oxide Synthase; Vasodilation | 2020 |
High-throughput enrichment of temperature-sensitive argininosuccinate synthetase for two-stage citrulline production in E. coli.
Topics: Arginine; Argininosuccinate Synthase; Biomass; Citrulline; Escherichia coli; Escherichia coli Proteins; Flow Cytometry; Glucose; Metabolic Engineering; Plasmids; Proteomics; Temperature | 2020 |
Identification and Characterization of the Lactating Mouse Mammary Gland Citrullinome.
Topics: Animals; Arginine; Cells, Cultured; Citrullination; Citrulline; Female; Gas Chromatography-Mass Spectrometry; Gene Expression; Histones; Humans; Lactation; Mammary Glands, Animal; Mice; Milk Proteins; Prolactin; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Proteome; Proteomics; RNA, Messenger; Time Factors | 2020 |
Maternal supplementation with citrulline or arginine during gestation impacts fetal amino acid availability in a model of intrauterine growth restriction (IUGR).
Topics: Amino Acids; Animals; Arginine; Citrulline; Diet, Protein-Restricted; Dietary Supplements; Disease Models, Animal; Female; Fetal Development; Fetal Growth Retardation; Fetus; Maternal Nutritional Physiological Phenomena; Pregnancy; Prenatal Care; Rats | 2020 |
Activiation of the nitric oxide cycle by citrulline and arginine restores susceptibility of resistant brown planthoppers to the insecticide imidacloprid.
Topics: Animals; Arginine; Citrulline; Hemiptera; Imidazoles; Insecticides; Neonicotinoids; Nitric Oxide; Nitro Compounds | 2020 |
l-Arginine supplementation in severe asthma.
Topics: Adolescent; Arginine; Asthma; Citrulline; Dietary Supplements; Double-Blind Method; Exhalation; Female; Humans; Male; Middle Aged; Nitric Oxide | 2020 |
Nitric Oxide Synthase activity in major depressive episodes before and after antidepressant treatment: Results of a large case-control treatment study.
Topics: Antidepressive Agents; Arginine; Case-Control Studies; Citrulline; Depressive Disorder, Major; Humans; Nitric Oxide Synthase | 2022 |
Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation.
Topics: Animals; Arginine; Breast Neoplasms; Citrullination; Citrulline; Female; Glycosylation; Histones; Humans; MCF-7 Cells; Methylation; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Nucleosomes; Protein-Arginine Deiminase Type 4; Pyruvaldehyde | 2020 |
Comprehensive arginine metabolomics and peripheral vasodilatory capacity in rheumatoid arthritis: A monocentric cross-sectional study.
Topics: Aged; Aged, 80 and over; Arginine; Arthritis, Rheumatoid; Biomarkers; Case-Control Studies; Citrulline; Cross-Sectional Studies; Female; Fingers; Homoarginine; Humans; Italy; Male; Metabolomics; Middle Aged; Vasodilation | 2020 |
Substitution of high-dose sucrose with fructose in high-fat diets resulted in higher plasma concentrations of aspartic acid, cystine, glutamic acid, ornithine and phenylalanine, and higher urine concentrations of arginine and citrulline.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Blood Glucose; Citrulline; Cystine; Diet, High-Fat; Dietary Sucrose; Dietary Sugars; Fructose; Glutamic Acid; Lipids; Male; Ornithine; Phenylalanine; Rats; Rats, Wistar | 2020 |
Arginine/citrulline cycle changes in diet-induced rat model of non-alcoholic fatty liver disease.
Topics: Animals; Arginine; Citrulline; Diet; Female; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley | 2020 |
IFN-γ Activates the TLR4-CCL5 Signaling Through Reducing Arginine Level, Leading to Enhanced Susceptibility of Bovine Mammary Epithelial Cells to Staphylococcus aureus.
Topics: Animals; Arginine; Bacterial Adhesion; Cattle; Chemokine CCL5; Citrulline; Epithelial Cells; Female; Interferon-gamma; Mammary Glands, Animal; Mastitis; Mice; Ornithine; Rats; Signal Transduction; Staphylococcus aureus; Toll-Like Receptor 4 | 2020 |
Translational Detection of Nonproteinogenic Amino Acids Using an Engineered Complementary Cell-Free Protein Synthesis Assay.
Topics: Amino Acid Sequence; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carboxyl and Carbamoyl Transferases; Cell Extracts; Citrulline; Escherichia coli; Ornithine; Protein Processing, Post-Translational; Proteins; Proteomics; Stereoisomerism; Substrate Specificity | 2020 |
Dietary arginine and citrulline supplementation modulates the immune condition and inflammatory response of European seabass.
Topics: Animal Feed; Animals; Arginine; Bass; Citrulline; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Fish Diseases; Gram-Negative Bacterial Infections; Immunity, Innate; Inflammation; Photobacterium; Random Allocation | 2020 |
Short-Term Supplementation of Dietary Arginine and Citrulline Modulates Gilthead Seabream (
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Biomarkers; Citrulline; Dietary Supplements; Gene Expression Profiling; Immunity, Innate; Leukocytes; Proteome; Proteomics; Sea Bream | 2020 |
Plasma citrulline correlates with basolateral amino acid transporter LAT4 expression in human small intestine.
Topics: Adult; Aged; Arginine; Body Mass Index; Citrulline; Enterocytes; Female; Gene Expression; Humans; Intestine, Small; Male; Middle Aged; RNA, Messenger; Young Adult | 2021 |
Valproic acid up-regulates the whole NO-citrulline cycle for potent iNOS-NO signaling to promote neuronal differentiation of adipose tissue-derived stem cells.
Topics: Adipose Tissue; Animals; Arginine; Argininosuccinate Synthase; Cell Differentiation; Citrulline; Enzyme Inhibitors; Male; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase Type II; Rats, Wistar; Signal Transduction; Stem Cells; Up-Regulation; Valproic Acid | 2021 |
Arginase II Plays a Central Role in the Sexual Dimorphism of Arginine Metabolism in C57BL/6 Mice.
Topics: Amino Acids; Animals; Arginase; Arginine; Citrulline; Female; Gene Expression Regulation, Enzymologic; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Knockout | 2020 |
Benchmark Examination of Blood Amino Acids Patterns in Phenylketonuria Neonates and Young Children on Phenylalanine-Restricted Dietary Treatment.
Topics: Arginine; Benchmarking; Child; Child, Preschool; Citrulline; Diet; Humans; Infant, Newborn; Methionine; Phenylalanine; Phenylketonurias; Proline; Tyrosine; Valine | 2022 |
Arginine Biosynthesis by a Bacterial Symbiont Enables Nitric Oxide Production and Facilitates Larval Settlement in the Marine-Sponge Host.
Topics: Animals; Aquatic Organisms; Arginine; Bacteria; Citrulline; Larva; Metamorphosis, Biological; Nitric Oxide; Porifera; Seawater; Symbiosis | 2021 |
Single-Laboratory Validation Study of a Proton NMR Method for the Determination of L-Arginine, L-Citrulline, and Taurine Contents in Dietary Supplements.
Topics: Arginine; Citrulline; Dietary Supplements; Laboratories; Magnetic Resonance Spectroscopy; Protons; Taurine | 2020 |
The shifted balance of arginine metabolites in acute myocardial infarction patients and its clinical relevance.
Topics: Arginine; Citrulline; Coronary Angiography; Female; Humans; Male; Middle Aged; Ornithine; Proline; ST Elevation Myocardial Infarction; Treatment Outcome | 2021 |
Is the decrease in NO
Topics: Arginine; Citrulline; Depression; Depressive Disorder, Major; Humans; Nitric Oxide Synthase | 2021 |
Pegylated arginine deiminase depletes plasma arginine but maintains tissue arginine availability in young pigs.
Topics: Animals; Arginine; Biological Availability; Citrulline; Female; Hydrolases; Kinetics; Male; Polyethylene Glycols; Swine; Tissue Distribution | 2021 |
Intrathecal and systemic alterations of L-arginine metabolism in patients after intracerebral hemorrhage.
Topics: Aged; Arginine; Case-Control Studies; Cerebral Hemorrhage; Chromatography, High Pressure Liquid; Citrulline; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Risk Factors; Tandem Mass Spectrometry; Up-Regulation | 2021 |
Association of proton pump inhibitor use with endothelial function and metabolites of the nitric oxide pathway: A cross-sectional study.
Topics: Arginine; Citrulline; Cross-Sectional Studies; Endothelium, Vascular; Female; Humans; Male; Nitric Oxide; Proton Pump Inhibitors | 2021 |
Autocitrullination of PAD4 does not alter its enzymatic activity: In vitro and in silico studies.
Topics: Arginine; Arthritis, Rheumatoid; Citrullination; Citrulline; Computer Simulation; Enzyme Assays; Humans; In Vitro Techniques; Mass Spectrometry; Molecular Dynamics Simulation; Protein-Arginine Deiminase Type 4; Recombinant Proteins | 2021 |
Gene delivery corrects N-acetylglutamate synthase deficiency and enables insights in the physiological impact of L-arginine activation of N-acetylglutamate synthase.
Topics: Amino-Acid N-Acetyltransferase; Animals; Arginine; Citrulline; Dependovirus; Disease Models, Animal; Gene Transfer Techniques; Glutamates; Humans; Hyperammonemia; Mice; Mice, Knockout; Mutant Proteins; Urea; Urea Cycle Disorders, Inborn | 2021 |
Longitudinal associations of physical activity with plasma metabolites among colorectal cancer survivors up to 2 years after treatment.
Topics: Aged; Arginine; Cancer Survivors; Carnitine; Citrulline; Colorectal Neoplasms; Exercise; Female; Histidine; Humans; Longitudinal Studies; Lysophosphatidylcholines; Male; Metabolome; Middle Aged; Quality of Life; Self Report; Sphingomyelins; Tandem Mass Spectrometry | 2021 |
Cortisol enhances citrulline synthesis from proline in enterocytes of suckling piglets.
Topics: Animals; Animals, Suckling; Arginine; Cell Proliferation; Citrulline; Enterocytes; Glutamine; Hydrocortisone; Ileum; Jejunum; Male; Proline; Proline Oxidase; Protein Biosynthesis; Swine | 2021 |
A Cross-Talk between the Erythrocyte L-Arginine/ADMA/Nitric Oxide Metabolic Pathway and the Endothelial Function in Subjects with Type 2 Diabetes Mellitus.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Citrulline; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Endothelium, Vascular; Erythrocytes; Female; Humans; Male; Metabolic Networks and Pathways; Middle Aged; Nitric Oxide | 2021 |
Altered L-Arginine Metabolic Pathways in Gastric Cancer: Potential Therapeutic Targets and Biomarkers.
Topics: Aged; Arginine; Argininosuccinate Lyase; Cell Differentiation; Citrulline; DNA, Complementary; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Male; Mass Spectrometry; Metabolomics; Middle Aged; Mitochondrial Membrane Transport Proteins; Neoplasm Metastasis; Nitric Oxide Synthase Type II; Ornithine; Polymerase Chain Reaction; Protein-Arginine N-Methyltransferases; Reproducibility of Results; Stomach Neoplasms; Transcriptome | 2021 |
A Streamlined Data Analysis Pipeline for the Identification of Sites of Citrullination.
Topics: Algorithms; Arginine; Citrullination; Citrulline; Data Analysis; Data Management; Data Mining; Humans; Peptides; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Proteomics; Tandem Mass Spectrometry | 2021 |
Plasma levels of amino acids and derivatives in retinopathy of prematurity.
Topics: 2-Aminoadipic Acid; Amino Acids; Arginine; Biomarkers; Citrulline; Creatinine; Female; Humans; Infant, Newborn; Infant, Premature; Male; Metabolomics; Retinopathy of Prematurity | 2021 |
Plasma Arginine and Citrulline are Elevated in Diabetic Retinopathy.
Topics: Adult; Arginine; Chromatography, Liquid; Citrulline; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Humans; Tandem Mass Spectrometry | 2022 |
L-Arginine Nutrition and Metabolism in Ruminants.
Topics: Animals; Arginine; Cattle; Citrulline; Diet; Dietary Supplements; Endothelial Cells; Female; Lactation; Milk; Pregnancy; Ruminants; Sheep | 2022 |
Dysregulated Arginine Metabolism in Young Patients with Chronic Persistent Asthma and in Human Bronchial Epithelial Cells.
Topics: Adult; Arginine; Asthma; Bronchi; Case-Control Studies; Cell Culture Techniques; Chronic Disease; Citrulline; Eosinophils; Epithelial Cells; Female; Humans; Male; Nitric Oxide; Ornithine; Prospective Studies; Young Adult | 2021 |
Regulation of citrulline synthesis in human enterocytes: Role of hypoxia and inflammation.
Topics: Arginine; Citrulline; Enterocytes; Humans; Hypoxia; Inflammation | 2022 |
Biochemical and biophysical characterization of PADI4 supports its involvement in cancer.
Topics: Arginine; Biomarkers, Tumor; Carcinogenesis; Catalysis; Cell Differentiation; Cell Line, Tumor; Citrulline; Gene Expression Regulation; Humans; Molecular Dynamics Simulation; Protein Binding; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Signal Transduction; Tumor Suppressor Protein p53 | 2022 |
Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction.
Topics: Animals; Arginine; Biological Availability; Citrulline; Cytokines; Disease Models, Animal; Female; Immune Tolerance; Immunosuppression Therapy; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mitochondria; Myeloid-Derived Suppressor Cells; Sepsis; T-Lymphocytes; T-Lymphocytes, Regulatory | 2022 |
Equine enterocytes actively oxidize l-glutamine, but do not synthesize l-citrulline or l-arginine from l-glutamine or l-proline in vitro.
Topics: Animals; Arginine; Carbon Dioxide; Citrulline; Enterocytes; Glutamine; Horses; Ornithine; Proline | 2022 |
Serum metabolomic signatures of gestational diabetes in South Asian and white European women.
Topics: Arginine; Asian People; Canada; Citrulline; Creatinine; Diabetes, Gestational; Female; Glucose; Glutamic Acid; Glutamine; Humans; Ornithine; Pregnancy; Prospective Studies | 2022 |
Free Amino Acids and Volatile Aroma Compounds in Watermelon Rind, Flesh, and Three Rind-Flesh Juices.
Topics: Alcohols; Aldehydes; Arginine; Carbon; Citrulline; Citrullus; Fruit; Odorants | 2022 |
Metabolic characterization of amniotic fluid of fetuses with isolated choroid plexus cyst.
Topics: Amniotic Fluid; Arginine; Aspartic Acid; Choroid Plexus; Citrulline; Coenzyme A; Cysts; Ethanolamines; Female; Glucose; Humans; Hydroxylysine; Isoleucine; Leucine; Pregnancy; Proline; Ultrasonography, Prenatal; Valine | 2022 |
PAD2 immunization induces ACPA in wild-type and HLA-DR4 humanized mice.
Topics: Alleles; Animals; Arginine; Arthritis, Rheumatoid; Autoantibodies; Citrulline; HLA-DR4 Antigen; HLA-DRB1 Chains; Immunization; Mice; Mice, Inbred C3H; Mice, Inbred C57BL | 2022 |
Characterization of a recombinant arginine deiminase from Halothermothrix orenii and its application in citrulline production.
Topics: Arginine; Citrulline; Hydrolases | 2023 |
Citrullination is linked to reduced Ca
Topics: Actins; Animals; Arginine; Arthritis, Experimental; Arthritis, Rheumatoid; Citrullination; Citrulline; Disease Models, Animal; Heart Failure; Hydrolases; Mice; Protein-Arginine Deiminases; Tumor Necrosis Factor-alpha | 2022 |
Raised total methylated arginine load in patients with gout.
Topics: Arginine; Citrulline; Gout; Homoarginine; Humans; Nitric Oxide; Ornithine | 2022 |
Effect of microencapsulated watermelon (Citrullus Lanatus) rind on flow-mediated dilation and tissue oxygen saturation of young adults.
Topics: Arginine; Citrulline; Citrullus; Dilatation; Humans; Oxygen Saturation; Young Adult | 2023 |
PAD4-dependent citrullination of nuclear translocation of GSK3β promotes colorectal cancer progression via the degradation of nuclear CDKN1A.
Topics: Arginine; Biomarkers; Citrullination; Citrulline; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Glycogen Synthase Kinase 3 beta; Humans; Hydrolases; Kruppel-Like Transcription Factors; Proteasome Endopeptidase Complex; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Transcription Factors; Ubiquitins | 2022 |
Comparative structural insight into the unidirectional catalysis of ornithine carbamoyltransferases from Psychrobacter sp. PAMC 21119.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Carbamyl Phosphate; Catalysis; Citrulline; Cyclohexanones; Ornithine; Ornithine Carbamoyltransferase; Psychrobacter | 2022 |
Association of amino acids related to urea cycle with risk of diabetic nephropathy in two independent cross-sectional studies of Chinese adults.
Topics: Adult; Arginine; Citrulline; Cross-Sectional Studies; Diabetes Mellitus; Diabetic Nephropathies; Humans; Ornithine; Urea | 2022 |
Delayed puberty, gonadotropin abnormalities and subfertility in male Padi2/Padi4 double knockout mice.
Topics: Animals; Arginine; Citrulline; Disease Models, Animal; Female; Gonadotropins; Hydrolases; Infertility; Male; Mice; Mice, Knockout; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Testosterone | 2022 |
A simple screening method for heterozygous female patients with ornithine transcarbamylase deficiency.
Topics: Arginine; Child; Citrulline; Female; Glutamine; Heterozygote; Humans; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Retrospective Studies | 2022 |
Preface to Nitric Oxide Modulators in Health and Disease I.
Topics: Arginine; Citrulline; Nitric Oxide; Nitric Oxide Synthase | 2022 |
Pharmacokinetics of L-Citrulline in Neonates at Risk of Developing Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension.
Topics: Arginine; Bronchopulmonary Dysplasia; Child; Citrulline; Gestational Age; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn | 2023 |
The impact of L-citrulline on murine intestinal cell integrity, immune response, and arginine metabolism in the face of Giardia lamblia infection.
Topics: Animals; Arginase; Arginine; Citrulline; Cysts; Giardia; Giardia lamblia; Giardiasis; Immunity; Male; Metronidazole; Mice; Rats; Trophozoites | 2023 |
TRAUMA INDUCES INTRAVASCULAR HEMOLYSIS, EXACERBATED BY RED BLOOD CELL TRANSFUSION AND ASSOCIATED WITH DISRUPTED ARGININE-NITRIC OXIDE METABOLISM.
Topics: Arginase; Arginine; Citrulline; Erythrocyte Transfusion; Hemolysis; Humans; Multiple Organ Failure; Nitric Oxide | 2023 |
Effect of Obstructive Sleep Apnea and CPAP Treatment on the Bioavailability of Erythrocyte and Plasma Nitric Oxide.
Topics: Arginine; Citrulline; Continuous Positive Airway Pressure; Erythrocytes; Humans; Nitric Oxide; Nitric Oxide Synthase; Prospective Studies; Sleep Apnea, Obstructive | 2022 |
Ammonia detoxification promotes CD8
Topics: Ammonia; Arginase; Arginine; CD8-Positive T-Lymphocytes; Citrulline; Nitric Oxide; Urea | 2023 |
Determination of equilibria constants of arginine:glycine amidinotransferase (AGAT)-catalyzed reactions using concentrations of circulating amino acids.
Topics: Amidinotransferases; Arginine; Catalysis; Citrulline; Homoarginine; Humans; Muscular Dystrophy, Duchenne | 2023 |
Metabolomic Analysis of Microcystis aeruginosa After Exposure to the Algicide L-Lysine.
Topics: Ammonia; Arginine; Citrulline; Cyanobacteria; Ecosystem; Herbicides; Humans; Lysine; Microcystins; Microcystis; Ornithine | 2022 |
Citrulline enteral administration markedly reduces immunosuppressive extrafollicular plasma cell differentiation in a preclinical model of sepsis.
Topics: Animals; Arginine; Cell Differentiation; Citrulline; Coinfection; Immunosuppressive Agents; Mice; Sepsis | 2023 |
Subchronic tolerance trials of graded oral supplementation with ornithine hydrochloride or citrulline in healthy adults.
Topics: Adult; Arginine; Aspartic Acid; Citrulline; Dietary Supplements; Glutamic Acid; Humans; Male; Ornithine | 2023 |
A Low Arginine/Ornithine Ratio is Associated with Long-Term Cardiovascular Mortality.
Topics: Aged; Arginine; Citrulline; Female; Humans; Hypertension; Male; Middle Aged; Ornithine; Prognosis | 2023 |
Novel method to quantify peptidylarginine deiminase activity shows distinct citrullination patterns in rheumatoid and juvenile idiopathic arthritis.
Topics: Arginine; Arthritis, Juvenile; Arthritis, Rheumatoid; Citrullination; Citrulline; Humans; Hydrolases; Protein-Arginine Deiminases; Proteins | 2023 |
Urinary excretion of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine is positively related to nitric oxide level in tissues of normotensive and hypertensive rats.
Topics: Animals; Arginine; Chromatography, Liquid; Citrulline; Hypertension; Male; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tandem Mass Spectrometry | 2023 |
Associations of serum amino acids related to urea cycle with risk of chronic kidney disease in Chinese with type 2 diabetes.
Topics: Arginine; Citrulline; Diabetes Mellitus, Type 2; East Asian People; Female; Humans; Male; Ornithine; Renal Insufficiency, Chronic; Urea | 2023 |
Editorial for the Special Issue "Benefits of Supplementation with L-arginine, Citrulline and Watermelon on Vascular and Metabolic Health".
Topics: Arginine; Blood Pressure; Citrulline; Citrullus; Dietary Supplements | 2023 |
Dietary supplementation with L-citrulline improves placental angiogenesis and embryonic survival in gilts.
Topics: Animals; Arginine; Citrulline; Dietary Supplements; Female; Guanosine Triphosphate; Placenta; Polyamines; Pregnancy; Swine | 2023 |
Arginine concentration in arterial vs venous blood in a bleomycin-induced lung inflammation model in mice.
Topics: Animals; Arginine; Bleomycin; Citrulline; COVID-19; Endothelial Cells; Humans; Lung; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Pandemics; Pneumonia | 2023 |
Plasma arginine metabolites in health and chronic kidney disease.
Topics: Arginine; Cardiovascular Diseases; Citrulline; Humans; Kidney; Renal Insufficiency, Chronic | 2023 |
Low Plasma Citrulline Guiding the Diagnosis of a Mitochondrial Disorder.
Topics: Arginine; Citrulline; Humans; Mitochondrial Diseases | 2023 |
Defects in intratumoral arginine metabolism attenuate the replication and therapeutic efficacy of oncolytic myxoma virus.
Topics: Arginine; Citrulline; Humans; Myxoma virus; Neoplasms; Oncolytic Viruses | 2023 |
Phenotypic characteristics of asthma and morbidity are associated with distinct longitudinal changes in L-arginine metabolism.
Topics: Arginine; Asthma; Citrulline; Humans; Morbidity; Ornithine; Phenotype; Prospective Studies; Quality of Life | 2023 |
Ornithine is the central intermediate in the arginine degradative pathway and its regulation in Bacillus subtilis.
Topics: Adenosine Triphosphate; Arginine; Bacillus subtilis; Bacterial Proteins; Citrulline; Ornithine; Sigma Factor; Transcription Factors | 2023 |
Arginine Dysregulation and Myocardial Dysfunction in a Mouse Model and Children with Chronic Kidney Disease.
Topics: Animals; Arginase; Arginine; Citrulline; Disease Models, Animal; Mice; Renal Dialysis; Renal Insufficiency, Chronic | 2023 |
Citrulline in the management of patients with urea cycle disorders.
Topics: Ammonia; Arginine; Citrulline; Drug-Related Side Effects and Adverse Reactions; Humans; Retrospective Studies; Urea; Urea Cycle Disorders, Inborn | 2023 |
The interaction of ammonia and manganese in abnormal metabolism of minimal hepatic encephalopathy: A comparison metabolomics study.
Topics: Alanine; Ammonia; Animals; Arginine; Brain; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Hyperammonemia; Inositol; Isoleucine; Lactic Acid; Leucine; Manganese; Metabolomics; Rats; Rats, Sprague-Dawley; Taurine | 2023 |
Plasma amino acid signatures define types of pediatric diabetes.
Topics: Adolescent; Arginine; Child; Citrulline; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fabaceae; Glutamine; Humans; Methionine; Pilot Projects; Racemethionine | 2023 |
Pentachlorophenol exposure induced neurotoxicity by disrupting citrulline metabolism in larvae and adult zebrafish.
Topics: Animals; Arginine; Citrulline; Larva; Ornithine; Pentachlorophenol; Proline; Zebrafish | 2023 |