citric acid, anhydrous and aminolevulinic acid

citric acid, anhydrous has been researched along with aminolevulinic acid in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's12 (52.17)24.3611
2020's11 (47.83)2.80

Authors

AuthorsStudies
Abe, F; Fujino, M; Ishii, T; Ishizuka, M; Ito, H; Li, XK; Nagahara, Y; Nakajima, M; Nishio, Y; Takahashi, K; Taketani, S; Tanaka, T; Zhao, M1
Abe, F; Chen, J; Chen, Y; Fujino, M; Guo, H; Hei, M; Huang, H; Huang, S; Ito, H; Li, J; Li, XK; Ma, X; Nakajima, M; Takahashi, K; Tanaka, T; Wang, J; Zhao, L; Zhao, M; Zheng, S; Zhu, P; Zhuang, J1
Ikegawa, S; Kamijo, Y; Kataoka, Y; Masuki, S; Morita, A; Nakajima, M; Nose, H; Ogawa, Y; Sumiyoshi, E; Takahashi, K; Tanaka, T1
Chen, J; Fujino, M; Ito, H; Li, XK; Nakajima, M; Nishio, Y; Takahashi, K; Tanaka, T; Zhao, L; Zhao, M; Zhu, P; Zhuang, J1
Al-Saber, F; Aldosari, W; Alselaiti, M; Darwish, A; Harb, G; Kaladari, A; Khalfan, H; Khan, G; Koda, A; Kudo, S; Nakajima, M; Rehani, R; Tanaka, T1
Fukuhara, H; Hara, T; Inoue, K; Ishizuka, M; Kamiya, A; Kitajima, Y; Koda, A; Kuroda, Y; Nakagawa, H; Nakajima, M; Ota, U; Shuin, T; Tanaka, T; Tsuda, M; Tsuru, E1
Hara, T; Ito, H; Li, XK; Nishio, Y; Sugihara, H; Tanaka, T1
Abbasi, GH; Ahmad, I; Ali, B; Ali, S; Bukhari, SAH; Farid, M; Hussain, A; Rizwan, M; Saeed, R; Zamir, MSI1
Fujino, M; Ito, H; Li, XK; Liu, C; Nakajima, M; Takahashi, K; Tanaka, T; Zhu, P; Zhu, S; Zhuang, J1
Fushimi, T; Ichimoto, K; Ishii, T; Kishita, Y; Matsunaga, A; Murayama, K; Nakajima, M; Nozawa, N; Ogawa-Tominaga, M; Ohtake, A; Okazaki, Y; Shimura, M; Tajika, M; Takahashi, K; Tanaka, T; Tsuruoka, T1
Hosogaya, N; Kawakami, A; Koga, T; Sato, S; Shimizu, T; Sumiyoshi, R; Tashiro, S; Yamamoto, H1
Guo, WZ; Hirano, H; Hu, X; Ishii, T; Ishizuka, M; Ito, H; Li, XK; Nakajima, M; Nozawa, N; Que, W; Takahashi, K; Tanaka, T; Wang, Z; Zhu, P1
Aizawa, S; Ando, K; Asada, A; Iijima, KM; Ishii, T; Ishizuka, M; Noguchi, M; Nozawa, N; Saito, T; Shinno, K; Tajima, M1
Chatziantonio, C; Negoro, H; Razzaque, MS1
Elgendy, O; Kitahara, G; Osawa, T; Taniguchi, S1
Iwanaga, K; Iwashima, A; Kawamura, K; Kojima, T; Matsushima, H; Mitsuishi, Y; Nakajima, M; Nakamura, S; Natsume, I; Nishi, K; Ohsaki, Y; Sakai, H; Sasaki, S; Sasaki, T; Sato, K; Shigenaga, T; Takahashi, K; Taniguchi, H; Yamauchi, M1
Auwerx, J; Benegiamo, G; Hosoda, S; Kitamura, N; Morel, JD; Nagano, U; Nakamura, A; Ogawa, Y; Taworntawat, T; Tsubota, K; Watanabe, M; Yokoyama, Y; Zhang, S1
Kamijo, YI; Masuki, S; Morikawa, A; Nakajima, M; Nose, H; Ogawa, Y; Suzuki, H; Takahashi, K1
Fujino, M; Isaka, Y; Ito, H; Li, XK; Liu, C; Nakajima, M; Takahashi, K; Tanaka, T; Zhu, P; Zhu, S1
Guo, WZ; Hu, X; Ito, H; Li, XK; Liu, C; Ma, K; Nakajima, M; Que, W; Ren, K; Takahashi, K; Tanaka, T; Wang, Z; Yi, SQ1
Fujine, K; Inaoka, DK; Kita, K; Kurosaki, Y; Morita, K; Ngwe Tun, MM; Sakura, T; Sakurai, Y; Yasuda, J1
Abiru, N; Haraguchi, A; Horie, I; Ito, A; Kawakami, A; Nakamura, Y; Shigeno, R1
Hu, X; Ito, H; Li, XK; Liu, C; Nakajima, M; Takahashi, K; Tanaka, T; Wang, Z; Zhu, P1

Trials

7 trial(s) available for citric acid, anhydrous and aminolevulinic acid

ArticleYear
Impact of 5-aminolevulinic acid with iron supplementation on exercise efficiency and home-based walking training achievement in older women.
    Journal of applied physiology (Bethesda, Md. : 1985), 2016, Jan-01, Volume: 120, Issue:1

    Topics: Accelerometry; Aged; Aminolevulinic Acid; Carbon Dioxide; Citric Acid; Cross-Over Studies; Diet; Dietary Supplements; Double-Blind Method; Exercise; Female; Ferrous Compounds; Humans; Lactic Acid; Middle Aged; Oxygen Consumption; Physical Conditioning, Human; Walking

2016
The Safety and Tolerability of 5-Aminolevulinic Acid Phosphate with Sodium Ferrous Citrate in Patients with Type 2 Diabetes Mellitus in Bahrain.
    Journal of diabetes research, 2016, Volume: 2016

    Topics: Abdominal Pain; Aminolevulinic Acid; Bahrain; Blood Glucose; Citric Acid; Cough; Diabetes Mellitus, Type 2; Diarrhea; Female; Ferrous Compounds; Glycated Hemoglobin; Humans; Male; Middle Aged; Phosphates; Pilot Projects; Single-Blind Method; Sodium

2016
Oral administration of 5-aminolevulinic acid induces heme oxygenase-1 expression in peripheral blood mononuclear cells of healthy human subjects in combination with ferrous iron.
    European journal of pharmacology, 2018, Aug-15, Volume: 833

    Topics: Administration, Oral; Adult; Aminolevulinic Acid; Citric Acid; Enzyme Induction; Ferrous Compounds; Heme Oxygenase-1; Humans; Leukocytes, Mononuclear; Male; Photosensitizing Agents; Young Adult

2018
Single-arm, open-label pilot intervention study to investigate an effect of oral 5-aminolevulinic acid plus sodium ferrous citrate on glucocorticoid reduction in patients with adult-onset Still disease: Study protocol for clinical trial (SPIRIT compliant)
    Medicine, 2020, Dec-11, Volume: 99, Issue:50

    Topics: Administration, Oral; Adult; Aminolevulinic Acid; Citric Acid; Drug Therapy, Combination; Female; Ferrous Compounds; Glucocorticoids; Heme; Heme Oxygenase-1; Humans; Japan; Male; Photosensitizing Agents; Pilot Projects; Safety; Still's Disease, Adult-Onset; Trace Elements; Treatment Outcome

2020
A Randomized Phase 2 Study of 5-Aminolevulinic Acid Hydrochloride and Sodium Ferrous Citrate for the Prevention of Nephrotoxicity Induced by Cisplatin-Based Chemotherapy of Lung Cancer.
    Oncology, 2022, Volume: 100, Issue:11

    Topics: Adult; Aged; Aminolevulinic Acid; Cisplatin; Citric Acid; Female; Humans; Lung Neoplasms; Male; Middle Aged

2022
Effects of 5-aminolevulinic acid supplementation on home-based walking training achievement in middle-aged depressive women: randomized, double-blind, crossover pilot study.
    Scientific reports, 2018, 05-08, Volume: 8, Issue:1

    Topics: Adult; Aged; Aminolevulinic Acid; Citric Acid; Combined Modality Therapy; Depressive Disorder, Major; Dietary Supplements; Double-Blind Method; Exercise Therapy; Female; Ferrous Compounds; Humans; Levulinic Acids; Middle Aged; Muscle Strength; Oxygen Consumption; Walking

2018
A single-arm, open-label, intervention study to investigate the improvement of glucose tolerance after administration of the 5-aminolevulinic acid (5-ALA) in the patients with mitochondrial diabetes mellitus.
    Medicine, 2021, Mar-12, Volume: 100, Issue:10

    Topics: Adenosine Triphosphate; Adult; Aminolevulinic Acid; Blood Glucose; Citric Acid; Deafness; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Ferrous Compounds; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Japan; Levulinic Acids; Male; Mitochondria; Mitochondrial Diseases; Pilot Projects; Treatment Outcome

2021

Other Studies

16 other study(ies) available for citric acid, anhydrous and aminolevulinic acid

ArticleYear
5-Aminolevulinic acid combined with ferrous iron enhances the expression of heme oxygenase-1.
    International immunopharmacology, 2014, Volume: 19, Issue:2

    Topics: Aminolevulinic Acid; Animals; Basic-Leucine Zipper Transcription Factors; Cell Line; Citric Acid; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; Ferrous Compounds; Heme Oxygenase-1; Membrane Proteins; Mice; p38 Mitogen-Activated Protein Kinases; RNA, Messenger; RNA, Small Interfering

2014
5-aminolevulinic acid combined with sodium ferrous citrate ameliorates H2O2-induced cardiomyocyte hypertrophy via activation of the MAPK/Nrf2/HO-1 pathway.
    American journal of physiology. Cell physiology, 2015, Apr-15, Volume: 308, Issue:8

    Topics: Aminolevulinic Acid; Animals; Antioxidants; Atrial Natriuretic Factor; Cardiomegaly; Cell Line; Citric Acid; Ferrous Compounds; Heme Oxygenase-1; Hydrogen Peroxide; Membrane Proteins; Mice; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Myosin Heavy Chains; Natriuretic Peptide, Brain; NF-E2-Related Factor 2; Oxidative Stress; RNA Interference; RNA, Small Interfering; Signal Transduction; Ventricular Myosins

2015
5-Aminolevulinic acid with sodium ferrous citrate induces autophagy and protects cardiomyocytes from hypoxia-induced cellular injury through MAPK-Nrf-2-HO-1 signaling cascade.
    Biochemical and biophysical research communications, 2016, Oct-28, Volume: 479, Issue:4

    Topics: Aminolevulinic Acid; Animals; Apoptosis; Autophagy; Cell Hypoxia; Chromones; Citric Acid; Enzyme Inhibitors; Ferrous Compounds; Heme Oxygenase-1; Ischemia; Kidney; Macrophages; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Morpholines; Myocytes, Cardiac; Oxidative Stress; Protective Agents; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Up-Regulation

2016
5-aminolevulinic acid combined with ferrous ion reduces adiposity and improves glucose tolerance in diet-induced obese mice via enhancing mitochondrial function.
    BMC pharmacology & toxicology, 2017, 01-30, Volume: 18, Issue:1

    Topics: 3T3 Cells; Adiposity; Aminolevulinic Acid; Animals; Citric Acid; Diet, High-Fat; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ferrous Compounds; Glucose; Glucose Tolerance Test; Male; Mice; Mice, Inbred C57BL; Mitochondria; Obesity

2017
Combined application of citric acid and 5-aminolevulinic acid improved biomass, photosynthesis and gas exchange attributes of sunflower (
    International journal of phytoremediation, 2019, Volume: 21, Issue:8

    Topics: Aminolevulinic Acid; Antioxidants; Biodegradation, Environmental; Biomass; Chromium; Citric Acid; Helianthus; Photosynthesis; Soil; Soil Pollutants

2019
5-ALA/SFC Attenuated Binge Alcohol-Induced Gut Leakiness and Inflammatory Liver Disease in HIV Transgenic Rats.
    Alcoholism, clinical and experimental research, 2019, Volume: 43, Issue:8

    Topics: Alanine Transaminase; Aminolevulinic Acid; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aspartate Aminotransferases; Binge Drinking; Cell Adhesion Molecules, Neuronal; Citric Acid; Endotoxins; Enterobacteriaceae Infections; Ethanol; Ferrous Compounds; gag Gene Products, Human Immunodeficiency Virus; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hepatitis; HIV Infections; HIV-1; Inflammation Mediators; Intestines; Lipopolysaccharides; Liver; Permeability; Rats; Rats, Transgenic; Receptors, Cell Surface; Sirtuin 1; Stem Cells; Triglycerides; Zonula Occludens-1 Protein

2019
Effects of 5-aminolevulinic acid and sodium ferrous citrate on fibroblasts from individuals with mitochondrial diseases.
    Scientific reports, 2019, 07-22, Volume: 9, Issue:1

    Topics: Adenosine Triphosphate; Aminolevulinic Acid; Biosynthetic Pathways; Case-Control Studies; Citric Acid; DNA Copy Number Variations; DNA, Mitochondrial; Female; Ferrous Compounds; Fibroblasts; Heme; Heme Oxygenase-1; Humans; In Vitro Techniques; Infant; Infant, Newborn; Male; Mitochondrial Diseases; Oxidative Phosphorylation; Oxygen Consumption; RNA, Messenger; Sodium Citrate; Up-Regulation

2019
5-Aminolevulinic acid/sodium ferrous citrate enhanced the antitumor effects of programmed cell death-ligand 1 blockade by regulation of exhausted T cell metabolism in a melanoma model.
    Cancer science, 2021, Volume: 112, Issue:7

    Topics: Adenosine Triphosphate; Aminolevulinic Acid; Animals; B7-H1 Antigen; Cell Line, Tumor; Citric Acid; Combined Modality Therapy; Female; Ferrous Compounds; Heme Oxygenase-1; Hepatitis A Virus Cellular Receptor 2; Ki-67 Antigen; Lymphocyte Activation; Lymphocyte Count; Lymphocytes, Tumor-Infiltrating; Melanoma, Experimental; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitochondria; Nuclear Respiratory Factor 1; Oxygen Consumption; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Sirtuin 1

2021
5-Aminolevulinic acid and sodium ferrous citrate ameliorate muscle aging and extend healthspan in Drosophila.
    FEBS open bio, 2022, Volume: 12, Issue:1

    Topics: Aminolevulinic Acid; Animals; Citric Acid; Drosophila; Drosophila melanogaster; Ferrous Compounds; Muscles

2022
Therapeutic potential of 5-aminolevulinic acid and sodium-ferrous citrate for viral insults: relevance to the COVID-19 crisis.
    Expert review of anti-infective therapy, 2022, Volume: 20, Issue:5

    Topics: Aminolevulinic Acid; Animals; Citric Acid; COVID-19 Drug Treatment; Ferrous Compounds; Heme; Heme Oxygenase-1; Humans; SARS-CoV-2; Sodium; Zika Virus; Zika Virus Infection

2022
5-Aminolevulinic acid combined with sodium ferrous citrate mitigates effects of heat stress on bovine oocyte developmental competence.
    The Journal of reproduction and development, 2022, Aug-01, Volume: 68, Issue:4

    Topics: Aminolevulinic Acid; Animals; Blastocyst; Cattle; Citric Acid; Cumulus Cells; Female; Ferrous Compounds; Heat-Shock Response; In Vitro Oocyte Maturation Techniques; Oocytes

2022
Sodium ferrous citrate and 5-aminolevulinic acid improve type 2 diabetes by maintaining muscle and mitochondrial health.
    Obesity (Silver Spring, Md.), 2023, Volume: 31, Issue:4

    Topics: Aminolevulinic Acid; Animals; Citric Acid; Diabetes Mellitus, Type 2; Diet, High-Fat; DNA, Mitochondrial; Ferrous Compounds; Insulin Resistance; Mice; Mice, Inbred C57BL; Mitochondria; Muscle, Skeletal

2023
5-ALA/SFC enhances HO-1 expression through the MAPK/Nrf2 antioxidant pathway and attenuates murine tubular epithelial cell apoptosis.
    FEBS open bio, 2019, Volume: 9, Issue:11

    Topics: Aminolevulinic Acid; Animals; Antioxidants; Apoptosis; Cells, Cultured; Citric Acid; Epithelial Cells; Ferrous Compounds; Heme Oxygenase-1; Kidney Tubules; Levulinic Acids; Mice; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2

2019
5-Aminolevulinic acid combined with sodium ferrous citrate (5-ALA/SFC) ameliorated liver injury in a murine acute graft-versus-host disease model by reducing inflammation responses through PGC1-α activation.
    Drug discoveries & therapeutics, 2021, Jan-23, Volume: 14, Issue:6

    Topics: Alanine Transaminase; Aminolevulinic Acid; Animals; Aspartate Aminotransferases; Citric Acid; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Ferrous Compounds; Gene Expression Regulation; Graft vs Host Disease; Levulinic Acids; Liver; Male; Mice; Mice, Inbred C57BL; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Sodium Citrate; T-Lymphocytes; Treatment Outcome; Up-Regulation

2021
5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro.
    Biochemical and biophysical research communications, 2021, 03-19, Volume: 545

    Topics: Aminolevulinic Acid; Animals; Antiviral Agents; Caco-2 Cells; Chlorocebus aethiops; Citric Acid; COVID-19; COVID-19 Drug Treatment; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ferrous Compounds; Humans; Levulinic Acids; Vero Cells

2021
5-aminolevulinic acid combined with sodium ferrous citrate ameliorated lupus nephritis in a mouse chronic graft-versus-host disease model.
    International immunopharmacology, 2021, Volume: 96

    Topics: Aminolevulinic Acid; Animals; B-Lymphocytes; Blood Urea Nitrogen; Body Weight; CD8-Positive T-Lymphocytes; Citric Acid; Creatine; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Female; Ferrous Compounds; Fibrosis; Graft vs Host Disease; Heme Oxygenase-1; Levulinic Acids; Lupus Nephritis; Lymphocyte Activation; Membrane Proteins; Mice; Spleen; T-Lymphocytes, Regulatory

2021