citraconic-acid and monomethyl-succinate

citraconic-acid has been researched along with monomethyl-succinate* in 1 studies

Other Studies

1 other study(ies) available for citraconic-acid and monomethyl-succinate

Article	Year
Fumarate reductase: structural and mechanistic insights from the catalytic reduction of 2-methylfumarate. FEBS letters, 2006, Mar-06, Volume: 580, Issue:6 The soluble fumarate reductase (FR) from Shewanella frigidimarina can catalyse the reduction of 2-methylfumarate with a k(cat) of 9.0 s(-1) and a K(M) of 32 microM. This produces the chiral molecule 2-methylsuccinate. Here, we present the structure of FR to a resolution of 1.5 A with 2-methylfumarate bound at the active site. The mode of binding of 2-methylfumarate allows us to predict the stereochemistry of the product as (S)-2-methylsuccinate. To test this prediction we have analysed the product stereochemistry by circular dichroism spectroscopy and confirmed the production of (S)-2-methylsuccinate. Topics: Catalysis; Circular Dichroism; Crystallography; Fumarates; Maleates; Oxidation-Reduction; Protein Conformation; Shewanella; Succinate Dehydrogenase; Succinates	2006

Article

Year

Fumarate reductase: structural and mechanistic insights from the catalytic reduction of 2-methylfumarate.

FEBS letters, 2006, Mar-06, Volume: 580, Issue:6

The soluble fumarate reductase (FR) from Shewanella frigidimarina can catalyse the reduction of 2-methylfumarate with a k(cat) of 9.0 s(-1) and a K(M) of 32 microM. This produces the chiral molecule 2-methylsuccinate. Here, we present the structure of FR to a resolution of 1.5 A with 2-methylfumarate bound at the active site. The mode of binding of 2-methylfumarate allows us to predict the stereochemistry of the product as (S)-2-methylsuccinate. To test this prediction we have analysed the product stereochemistry by circular dichroism spectroscopy and confirmed the production of (S)-2-methylsuccinate.

Topics: Catalysis; Circular Dichroism; Crystallography; Fumarates; Maleates; Oxidation-Reduction; Protein Conformation; Shewanella; Succinate Dehydrogenase; Succinates

2006