citalopram and n-methyl-3,4-methylenedioxyamphetamine

citalopram has been researched along with n-methyl-3,4-methylenedioxyamphetamine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.45)18.7374
1990's5 (16.13)18.2507
2000's13 (41.94)29.6817
2010's10 (32.26)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Ben-Daniel, R; Brust, P; Deuther-Conrad, W; Mishani, E; Scheunemann, M; Steinbach, J1
Butler, SG; Cloonan, SM; Corrigan, D; Jørgensen, AM; Keating, JJ; Knox, AJ; Lloyd, DG; Meegan, MJ; Peters, GH; Rai, D; Williams, DC1
Butler, SG; Cloonan, SM; Keating, JJ; Knox, AJ; McNamara, YM; Meegan, MJ; Peters, GH; Williams, DC1
Levin, JA; Lovenberg, W; Schmidt, CJ1
Schmidt, CJ; Taylor, VL1
Halme, M; Lauerma, H; Wuorela, M1
Butcher, SP; Lawrence, JA; Marston, HM; Olverman, HJ; Reid, ME1
Kristensen, AS; Mortensen, OV; Rudnick, G; Wiborg, O1
Rink, J; Stein, DJ1
McEvoy, C; Neumaier, JF; Sexton, TJ1
Baumann, C; Gamma, A; Liechti, ME; Vollenweider, FX1
Liechti, ME; Vollenweider, FX1
Geyer, MA; Hell, D; Liechti, ME; Vollenweider, FX1
Ceglia, I; Gobbi, M; Mennini, T; Moia, M; Pirona, L; Reyes-Parada, M; Scorza, C1
Kovar, KA; Lebsanft, HB; Mayerhofer, A; Schmidt, WJ1
Adkins, EM; Blakely, RD; Field, JR; Henry, LK; Newman, AH; Parnas, ML; Vaughan, RA; Zou, MF1
Bomsien, S; Skopp, G1
Ali, SF; Fraiman, JB; Meyer, JS; Owens, CB; Piper, BJ1
Fahey, MA; Fryer, AK; Lynch, L; Madras, BK; Miller, GM; Verrico, CD1
Allott, K; Broadbear, JH; Canny, BK; Murphy, B; Redman, J; Stepto, NK1
El Yacoubi, M; Hamon, M; Hanoun, N; Lanfumey, L; Lesch, KP; Melfort, M; Païzanis, E; Renoir, T; Saurini, F1
Adori, C; Andó, RD; Bagdy, G; Ferrington, L; Kelly, PA; Kirilly, E; Kovács, GG; Molnár, E1
Kittler, K; Lau, T; Schloss, P1
Ali, SF; Daniels, LG; Meyer, JS; Piper, BJ1
Drummer, OH; Gerostamoulos, D; Pilgrim, JL1
Amos-Kroohs, RM; Braun, AA; Grace, CE; Graham, DL; Schaefer, TL; Skelton, MR; Vorhees, CV; Williams, MT1
Hanck, L; Schellekens, AF1
Hentschke, H; Liebig, L; von Ameln-Mayerhofer, A1
Duffy, P; Gorman, I; Gormley, S; Harkin, A; Jennings-Murphy, C; Kelly, ME; Kerskens, CM; Rouine, J1
Chen, LC; Huang, YS; Kao, TJ; Li, IH; Lin, YY; Ma, KH; Weng, SJ; Yen, TY1
Islas, ÁA; Scior, T1

Trials

3 trial(s) available for citalopram and n-methyl-3,4-methylenedioxyamphetamine

ArticleYear
Acute psychological effects of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") are attenuated by the serotonin uptake inhibitor citalopram.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 22, Issue:5

    Topics: Adult; Amphetamine-Related Disorders; Brain; Citalopram; Double-Blind Method; Female; Hallucinogens; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neuropsychological Tests; Nootropic Agents; Selective Serotonin Reuptake Inhibitors

2000
The serotonin uptake inhibitor citalopram reduces acute cardiovascular and vegetative effects of 3,4-methylenedioxymethamphetamine ('Ecstasy') in healthy volunteers.
    Journal of psychopharmacology (Oxford, England), 2000, Volume: 14, Issue:3

    Topics: Adult; Animals; Blood Pressure; Body Temperature; Citalopram; Cross-Over Studies; Dopamine; Double-Blind Method; Female; Hallucinogens; Heart Rate; Humans; Male; Mental Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Placebos; Selective Serotonin Reuptake Inhibitors; Serotonin

2000
Neuroendocrine and subjective responses to pharmacological challenge with citalopram: a controlled study in male and female ecstasy/MDMA users.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:7

    Topics: Adult; Affect; Cannabis; Citalopram; Drug Users; Female; Humans; Hydrocortisone; Male; N-Methyl-3,4-methylenedioxyamphetamine; Personality; Prolactin; Selective Serotonin Reuptake Inhibitors; Sex Characteristics

2009

Other Studies

28 other study(ies) available for citalopram and n-methyl-3,4-methylenedioxyamphetamine

ArticleYear
Carbon-11 labeled indolylpropylamine analog as a new potential PET agent for imaging of the serotonin transporter.
    Bioorganic & medicinal chemistry, 2008, Jun-15, Volume: 16, Issue:12

    Topics: Animals; Carbon Radioisotopes; Cell Line; Humans; Indoles; Isoquinolines; Isotope Labeling; Ligands; Positron-Emission Tomography; Propylamines; Rats; Rats, Inbred Strains; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship

2008
Synthesis and serotonin transporter activity of sulphur-substituted alpha-alkyl phenethylamines as a new class of anticancer agents.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:12

    Topics: Amphetamines; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Phenethylamines; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Sulfur

2009
Synthesis and serotonin transporter activity of 1,3-bis(aryl)-2-nitro-1-propenes as a new class of anticancer agents.
    Bioorganic & medicinal chemistry, 2011, Feb-01, Volume: 19, Issue:3

    Topics: Alkenes; Antineoplastic Agents; Apoptosis; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Drug Design; Humans; Molecular Structure; Nitro Compounds; Serotonin; Serotonin Plasma Membrane Transport Proteins

2011
In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain.
    Biochemical pharmacology, 1987, Mar-01, Volume: 36, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Citalopram; Corpus Striatum; Dopamine; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; p-Chloroamphetamine; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism

1987
Depression of rat brain tryptophan hydroxylase activity following the acute administration of methylenedioxymethamphetamine.
    Biochemical pharmacology, 1987, Dec-01, Volume: 36, Issue:23

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Cerebral Cortex; Citalopram; Dose-Response Relationship, Drug; Fluoxetine; Ketanserin; Kinetics; Male; Methiothepin; N-Methyl-3,4-methylenedioxyamphetamine; Piperonyl Butoxide; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tryptophan Hydroxylase

1987
Interaction of serotonin reuptake inhibitor and 3,4-methylenedioxymethamphetamine?
    Biological psychiatry, 1998, Jun-15, Volume: 43, Issue:12

    Topics: Citalopram; Drug Interactions; Hallucinogens; Humans; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Selective Serotonin Reuptake Inhibitors

1998
Behavioural analysis of the acute and chronic effects of MDMA treatment in the rat.
    Psychopharmacology, 1999, Volume: 144, Issue:1

    Topics: Animals; Behavior, Animal; Biogenic Monoamines; Chromatography, High Pressure Liquid; Citalopram; Kinetics; Male; Mental Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Radioligand Assay; Rats

1999
Molecular cloning, expression and characterization of a bovine serotonin transporter.
    Brain research. Molecular brain research, 1999, Jul-23, Volume: 71, Issue:1

    Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cattle; Citalopram; Cloning, Molecular; Desipramine; Female; Fluoxetine; HeLa Cells; Humans; Imipramine; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Organ Specificity; Paroxetine; Phylogeny; Pregnancy; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin; Serotonin Plasma Membrane Transport Proteins; Transfection

1999
Effects of "Ecstasy" blocked by serotonin reuptake inhibitors.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:7

    Topics: Adult; Citalopram; Female; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Selective Serotonin Reuptake Inhibitors; Substance-Related Disorders; Trichotillomania

1999
(+) 3,4-methylenedioxymethamphetamine ('ecstasy') transiently increases striatal 5-HT1B binding sites without altering 5-HT1B mRNA in rat brain.
    Molecular psychiatry, 1999, Volume: 4, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Brain Chemistry; Citalopram; Corpus Striatum; Dose-Response Relationship, Drug; Gene Expression; Hippocampus; In Situ Hybridization; Iodine Radioisotopes; Iodocyanopindolol; N-Methyl-3,4-methylenedioxyamphetamine; Radioligand Assay; Raphe Nuclei; Rats; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Tritium

1999
Effects of MDMA (ecstasy) on prepulse inhibition and habituation of startle in humans after pretreatment with citalopram, haloperidol, or ketanserin.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:3

    Topics: Acoustic Stimulation; Adult; Citalopram; Dose-Response Relationship, Drug; Double-Blind Method; Female; Habituation, Psychophysiologic; Haloperidol; Humans; Ketanserin; Male; Models, Psychological; N-Methyl-3,4-methylenedioxyamphetamine; Psychiatric Status Rating Scales; Reflex, Startle; Selective Serotonin Reuptake Inhibitors; Serotonin

2001
p-Methylthioamphetamine and 1-(m-chlorophenyl)piperazine, two non-neurotoxic 5-HT releasers in vivo, differ from neurotoxic amphetamine derivatives in their mode of action at 5-HT nerve endings in vitro.
    Journal of neurochemistry, 2002, Volume: 82, Issue:6

    Topics: Amphetamines; Animals; Binding, Competitive; Brain Chemistry; Carrier Proteins; Citalopram; Dose-Response Relationship, Drug; Hippocampus; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Nerve Tissue Proteins; p-Chloroamphetamine; Piperazines; Rats; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Synaptosomes; Tritium

2002
Is the Ecstasy-induced ipsilateral rotation in 6-hydroxydopamine unilaterally lesioned rats dopamine independent?
    Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Agents; Animals; Apomorphine; Behavior, Animal; Citalopram; Dopamine; Fenclonine; Functional Laterality; Hallucinogens; Male; Medial Forebrain Bundle; Models, Animal; N-Methyl-3,4-methylenedioxyamphetamine; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotation; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists

2003
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
    The Journal of biological chemistry, 2006, Jan-27, Volume: 281, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Amino Acid Sequence; Animals; Antidepressive Agents; Binding Sites; Binding, Competitive; Blotting, Western; Cadmium; Cell Line; Cell Membrane; Citalopram; Clomipramine; Cocaine; Cysteine; Dopamine Uptake Inhibitors; Fluoxetine; HeLa Cells; Humans; Immunoprecipitation; Isoleucine; Kinetics; LLC-PK1 Cells; Mazindol; Methionine; Mice; Models, Chemical; Molecular Sequence Data; Mutation; N-Methyl-3,4-methylenedioxyamphetamine; Nomifensine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Radiopharmaceuticals; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Species Specificity; Stereoisomerism; Substrate Specificity; Tyrosine

2006
An in vitro approach to potential methadone metabolic-inhibition interactions.
    European journal of clinical pharmacology, 2007, Volume: 63, Issue:9

    Topics: Algorithms; Amitriptyline; Analgesics, Opioid; Atomoxetine Hydrochloride; Chromatography, Liquid; Citalopram; Clozapine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Isoenzymes; Kinetics; Methadone; Methylation; N-Methyl-3,4-methylenedioxyamphetamine; Oxidoreductases, N-Demethylating; Propylamines; Psychotropic Drugs; Pyridines; Pyrrolidines; Tandem Mass Spectrometry; Zolpidem

2007
Dissociation of the neurochemical and behavioral toxicology of MDMA ('Ecstasy') by citalopram.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:5

    Topics: Analysis of Variance; Animals; Behavior, Animal; Body Temperature; Body Weight; Brain Chemistry; Citalopram; Dose-Response Relationship, Drug; Ejaculation; Exploratory Behavior; Hallucinogens; Interpersonal Relations; Male; Maze Learning; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Selective Serotonin Reuptake Inhibitors; Time Factors

2008
MDMA-induced impairment in primates: antagonism by a selective norepinephrine or serotonin, but not by a dopamine/norepinephrine transport inhibitor.
    Journal of psychopharmacology (Oxford, England), 2008, Volume: 22, Issue:2

    Topics: Administration, Oral; Animals; Appetitive Behavior; Association Learning; Cell Line; Citalopram; Desipramine; Discrimination Learning; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Injections, Intramuscular; Macaca fascicularis; Male; Mental Recall; Methylphenidate; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine Plasma Membrane Transport Proteins; Reversal Learning; Serotonin Plasma Membrane Transport Proteins; Stereotyped Behavior

2008
Differential long-term effects of MDMA on the serotoninergic system and hippocampal cell proliferation in 5-HTT knock-out vs. wild-type mice.
    The international journal of neuropsychopharmacology, 2008, Volume: 11, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cell Proliferation; Citalopram; Electrophysiology; Female; Hallucinogens; Hindlimb Suspension; Hippocampus; Injections, Intraperitoneal; Male; Membranes; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Patch-Clamp Techniques; Raphe Nuclei; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Swimming

2008
Acute SSRI-induced anxiogenic and brain metabolic effects are attenuated 6 months after initial MDMA-induced depletion.
    Behavioural brain research, 2010, Mar-05, Volume: 207, Issue:2

    Topics: Animals; Anxiety; Axons; Brain; Citalopram; Fluoxetine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neuropsychological Tests; Piperazines; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Social Behavior; Time Factors

2010
Antagonists and substrates differentially regulate serotonin transporter cell surface expression in serotonergic neurons.
    European journal of pharmacology, 2010, Mar-10, Volume: 629, Issue:1-3

    Topics: Animals; Cell Line; Citalopram; Cocaine; Gene Expression Regulation; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Protein Transport; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins

2010
Repeated intermittent methylenedioxymethamphetamine exposure protects against the behavioral and neurotoxic, but not hyperthermic, effects of an MDMA binge in adult rats.
    Synapse (New York, N.Y.), 2010, Volume: 64, Issue:6

    Topics: Age Factors; Animals; Binding, Competitive; Body Temperature; Cerebral Cortex; Citalopram; Dose-Response Relationship, Drug; Drug Administration Schedule; Fever; Hippocampus; Hydroxyindoleacetic Acid; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxins; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins

2010
Deaths involving serotonergic drugs.
    Forensic science international, 2010, May-20, Volume: 198, Issue:1-3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Australia; Cause of Death; Citalopram; Cyclohexanols; Female; Fluoxetine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Serotonin Agents; Sertraline; Tramadol; Venlafaxine Hydrochloride

2010
Cognitive impairments from developmental exposure to serotonergic drugs: citalopram and MDMA.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:6

    Topics: Animals; Animals, Newborn; Body Weight; Citalopram; Cognition Disorders; Disease Models, Animal; Female; Locomotion; Male; Maze Learning; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Serotonin Agents; Swimming

2013
[Hallucinogen persisting perception disorder after ecstasy use].
    Nederlands tijdschrift voor geneeskunde, 2013, Volume: 157, Issue:24

    Topics: Anxiety Disorders; Citalopram; Depressive Disorder; Hallucinations; Hallucinogens; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Young Adult

2013
MDMA modulates spontaneous firing of subthalamic nucleus neurons in vitro.
    Experimental brain research, 2015, Volume: 233, Issue:1

    Topics: Action Potentials; Adrenergic Uptake Inhibitors; Animals; Citalopram; Desipramine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Rats; Rats, Sprague-Dawley; Serotonin Agents; Subthalamic Nucleus

2015
Investigation of the mechanisms mediating MDMA "Ecstasy"-induced increases in cerebro-cortical perfusion determined by btASL MRI.
    Psychopharmacology, 2015, Volume: 232, Issue:9

    Topics: Animals; Brain; Cerebrovascular Circulation; Citalopram; Dopamine Antagonists; Fenclonine; Fenfluramine; Magnetic Resonance Imaging; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Spin Labels

2015
Involvement of autophagy upregulation in 3,4-methylenedioxymethamphetamine ('ecstasy')-induced serotonergic neurotoxicity.
    Neurotoxicology, 2016, Volume: 52

    Topics: Adenine; Animals; Autophagy; Benzylamines; Brain Stem; Cells, Cultured; Citalopram; Dose-Response Relationship, Drug; Down-Regulation; Fluorine Radioisotopes; Functional Neuroimaging; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Neurites; Neuroprotective Agents; Phagosomes; Positron-Emission Tomography; Rats; Serotonergic Neurons; Serotonin Plasma Membrane Transport Proteins

2016
Allosteric Binding of MDMA to the Human Serotonin Transporter (hSERT) via Ensemble Binding Space Analysis with ΔG Calculations, Induced Fit Docking and Monte Carlo Simulations.
    Molecules (Basel, Switzerland), 2022, May-06, Volume: 27, Issue:9

    Topics: Antidepressive Agents; Citalopram; Humans; Monte Carlo Method; N-Methyl-3,4-methylenedioxyamphetamine; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins

2022