citalopram and metoprolol

citalopram has been researched along with metoprolol in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (11.54)18.2507
2000's11 (42.31)29.6817
2010's11 (42.31)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Jolivette, LJ; Ward, KW1
Jolivette, LJ; Nagilla, R; Ward, KW1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hjorth, S; Sharp, T1
Belpaire, FM; Brøsen, K; Rasmussen, BB; Temmerman, A; Wijnant, P1
Akarachkova, ES; Dlusskaia, IG; Striuk, RI; Tabeeva, GR; Veĭn, AM; Volkova, ZI1
Baker, B; Burt, T; Desta, Z; Flockhart, D; Greenblatt, DJ; Harmatz, JS; Klick-Davis, A; Luo, Y; Perloff, ES; Preskorn, SH1
Dolkart, O; Gigi, R; Katzburg, S; Salai, M; Somjen, D; Yakobson, O1
Dixit, S; Park, JH1
Park, JH; Park, JM1
Ahonen, R; Hartikainen, S; Koponen, M; Taipale, H; Tanskanen, A; Tiihonen, J; Tolppanen, AM1
Bahar, MA; Bos, JHJ; Hak, E; Wang, Y; Wilffert, B1
Arlı, G; Atkoşar, Z; Badulla, WFS; Dal Poçan, AG1

Reviews

1 review(s) available for citalopram and metoprolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for citalopram and metoprolol

ArticleYear
Comparison of duloxetine, escitalopram, and sertraline effects on cytochrome P450 2D6 function in healthy volunteers.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:1

    Topics: Adult; Antidepressive Agents; Citalopram; Cytochrome P-450 CYP2D6; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Male; Metoprolol; Middle Aged; Reference Values; Sertraline; Single-Blind Method; Thiophenes

2007

Other Studies

24 other study(ies) available for citalopram and metoprolol

ArticleYear
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
    Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2

    Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Citalopram; Dialysis; Hippocampus; Male; Metoprolol; Penbutolol; Perfusion; Pindolol; Propanolamines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stereoisomerism

1993
The oxidative metabolism of metoprolol in human liver microsomes: inhibition by the selective serotonin reuptake inhibitors.
    European journal of clinical pharmacology, 1998, Volume: 54, Issue:3

    Topics: 1-Naphthylamine; Adult; Anti-Arrhythmia Agents; Child; Citalopram; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Fluoxetine; Fluvoxamine; Humans; Hydroxylation; Kinetics; Male; Methylation; Metoprolol; Microsomes, Liver; Oxidation-Reduction; Paroxetine; Quinidine; Selective Serotonin Reuptake Inhibitors; Sertraline

1998
[Clinical significance of adrenoreactivity in patients with some paroxysmal disorders (panic attacks and migraine)].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2003, Volume: 103, Issue:1

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Citalopram; Diagnostic and Statistical Manual of Mental Disorders; Female; Fluoxetine; Humans; Hypertension; Male; Metoprolol; Migraine Disorders; Panic Disorder; Parasympathetic Nervous System; Selective Serotonin Reuptake Inhibitors; Surveys and Questionnaires; Sympathetic Nervous System

2003
Effects of commonly used medications on bone tissue mineralisation in SaOS-2 human bone cell line: an in vitro study.
    The bone & joint journal, 2013, Volume: 95-B, Issue:11

    Topics: Adrenergic beta-1 Receptor Antagonists; Bone and Bones; Calcification, Physiologic; Cell Line; Cell Proliferation; Citalopram; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Metoprolol; Omeprazole; Osteoblasts; Proton Pump Inhibitors; Pyrimidines; Rosuvastatin Calcium; Selective Serotonin Reuptake Inhibitors; Sulfonamides

2013
Penicillin G as a novel chiral selector in capillary electrophoresis.
    Journal of chromatography. A, 2014, Jan-24, Volume: 1326

    Topics: Anti-Bacterial Agents; Benzofurans; Citalopram; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Methanol; Metoprolol; Penicillin G; Propranolol; Pyrrolidines; Sertraline; Solubility; Stereoisomerism; Temperature

2014
Enantiomer separations of basic chiral compounds by capillary electrochromatography on a phosphated β-cyclodextrin-modified zirconia monolith.
    Journal of chromatography. A, 2014, Apr-25, Volume: 1339

    Topics: Atenolol; beta-Cyclodextrins; Buffers; Capillary Electrochromatography; Citalopram; Hydrogen-Ion Concentration; Metoprolol; Sertraline; Stereoisomerism; Zirconium

2014
From prescriptions to drug use periods - things to notice.
    BMC research notes, 2014, Nov-14, Volume: 7

    Topics: Alzheimer Disease; Citalopram; Diuretics; Dose-Response Relationship, Drug; Drug Labeling; Drug Prescriptions; Humans; Losartan; Metoprolol; Pharmaceutical Preparations; Tablets; Temazepam; Time Factors

2014
Discontinuation and dose adjustment of metoprolol after metoprolol-paroxetine/fluoxetine co-prescription in Dutch elderly.
    Pharmacoepidemiology and drug safety, 2018, Volume: 27, Issue:6

    Topics: Aged; Aged, 80 and over; Citalopram; Cohort Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Prescriptions; Drug Therapy, Combination; Female; Fluoxetine; Humans; Male; Metoprolol; Middle Aged; Mirtazapine; Netherlands; Paroxetine

2018
Capillary Electrophoresis Method for Determination of Escitalopram Oxalate in Urine Samples and Different Dosage Forms.
    Journal of chromatographic science, 2020, Aug-21, Volume: 58, Issue:8

    Topics: Citalopram; Dosage Forms; Electrophoresis, Capillary; Humans; Limit of Detection; Linear Models; Metoprolol; Reproducibility of Results

2020