citalopram and mecamylamine

citalopram has been researched along with mecamylamine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Isgor, C; Ma, Z; Pearson, E; Tao, R1
Andreasen, JT; Redrobe, JP1
Lindsley, CW1
Gruca, P; Lason-Tyburkiewicz, M; Litwa, E; Papp, M; Willner, P1
Demyttenaere, K; Dunbar, G; Eriksson, H; Hosford, D; Möller, HJ; Olausson, B; Szamosi, J; Tummala, R; Wilson, E1

Reviews

1 review(s) available for citalopram and mecamylamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for citalopram and mecamylamine

ArticleYear
(S)-(+)-mecamylamine (TC-5214): a neuronal nicotinic receptor modulator enters phase III trials as an adjunct treatment for Major Depressive Disorder (MDD).
    ACS chemical neuroscience, 2010, Aug-18, Volume: 1, Issue:8

    Topics: Animals; Antidepressive Agents; Citalopram; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Double-Blind Method; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Mecamylamine; Molecular Structure; Multicenter Studies as Topic; Nicotinic Antagonists; Patient Selection; Randomized Controlled Trials as Topic; Receptors, Nicotinic; Selective Serotonin Reuptake Inhibitors; Stereoisomerism

2010
Two Phase III randomised double-blind studies of fixed-dose TC-5214 (dexmecamylamine) adjunct to ongoing antidepressant therapy in patients with major depressive disorder and an inadequate response to prior antidepressant therapy.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2015, Volume: 16, Issue:7

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Mecamylamine; Middle Aged; Psychiatric Status Rating Scales; Sertraline; Treatment Outcome; Young Adult

2015

Other Studies

4 other study(ies) available for citalopram and mecamylamine

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Evidence of reuptake inhibition responsible for mecamylamine-evoked increases in extracellular serotonin.
    Brain research, 2006, Feb-16, Volume: 1073-1074

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aconitine; Animals; Citalopram; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Mecamylamine; Microdialysis; Nicotinic Antagonists; Raphe Nuclei; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Wakefulness

2006
Nicotine, but not mecamylamine, enhances antidepressant-like effects of citalopram and reboxetine in the mouse forced swim and tail suspension tests.
    Behavioural brain research, 2009, Jan-30, Volume: 197, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Mecamylamine; Mice; Morpholines; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Norepinephrine; Reboxetine; Receptors, Nicotinic; Selective Serotonin Reuptake Inhibitors; Serotonin

2009
Effects of chronic mild stress on the development of drug dependence in rats.
    Behavioural pharmacology, 2014, Volume: 25, Issue:5-6

    Topics: Animals; Chronic Disease; Citalopram; Depressive Disorder; Diazepam; Disease Models, Animal; Flumazenil; GABA Modulators; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Substance Withdrawal Syndrome; Substance-Related Disorders

2014