citalopram and clomipramine

citalopram has been researched along with clomipramine in 109 studies

Research

Studies (109)

TimeframeStudies, this research(%)All Research%
pre-199019 (17.43)18.7374
1990's31 (28.44)18.2507
2000's31 (28.44)29.6817
2010's26 (23.85)24.3611
2020's2 (1.83)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Eid, NM; George, RF; Hanna, MM; Safwat, HM1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kato, H; Kogure, K; Nakata, N1
Blier, P; de Montigny, C1
Chilco, PJ; Donnan, GA; Kaczmarczyk, SJ; Kalnins, RM; Mendelsohn, FA; Paxinos, G; Woodhouse, DG1
Insel, TR; Winslow, JT1
Gibb, JW; Hanson, GR; Ritter, JK; Schmidt, CJ1
Lovenberg, W; Schmidt, CJ1
Fasmer, OB; Hole, K; Hunskaar, S1
Andersson, A; Bäckström, I; Marcusson, JO1
Fuller, RW1
Briley, M; Moret, C1
Graham, D; Langer, SZ; Tahraoui, L1
Eriksson, K; Marcusson, J1
Collard, KJ; Evans, SM1
Christensen, P1
Bech, P; Haaber, A; Joyce, CR1
Gibb, JW; Schmidt, CJ1
Conquy, T; Durand, A; Rop, PP; Viala, A1
Lingjaerde, O1
Christensen, P; Gram, LF; Kragh-Sørensen, P; Pedersen, OL; Thomsen, HY1
Pawłowski, L1
Buckholtz, NS; Sparks, DL1
Constantinidis, J; Dick, P; Tissot, R1
Bastide, P; Coudert, P; Rubat, C; Tronche, P1
Adrien, J; Hamon, M; Maudhuit, C2
Neuvonen, PJ; Pohjola-Sintonen, S; Tacke, U; Vuori, E1
Hayakawa, H; Kawai, K; Kikumoto, O; Motohashi, N; Nishida, A; Okamoto, Y; Tanra, AJ; Yamawaki, S1
Buchholtz-Hansen, PE; Kragh-Sørensen, P; Wang, AG1
Depierre, JW; Nässberger, L; Xia, Z2
Bech, P; Damsbo, N; Fuglum, E; Lauritzen, L; Rosenberg, C; Stage, K1
Berk, M; Koopowitz, LF; Szabo, CP1
Harnett-Sheehan, K; Sheehan, DV1
Kagaya, A; Uchitomi, Y; Yamaji, T; Yamawaki, S; Yokota, N1
Bouwer, C; Stein, DJ; van Heerden, B1
Appelkvist, EL; DePierre, JW; Nässberger, L; Xia, Z1
Balant, L; Busquets, X; Escribá, PV; García-Sevilla, JA; Guimón, J; Walzer, C1
Koponen, HJ; Lepola, U; Pedersen, T; Pedersen, V; Wade, AG1
Pidrman, V; Tůma, I1
Betz, H; Schloss, P; Sur, C1
Stein, MB1
Bejerot, S; Bodlund, O1
Meyers, BS1
Baumann, P; Bryois, C; Buclin, T; Kosel, M; Rubin, C; Voirol, P1
Bergstrand, A; DePierre, JW; Nässberger, L; Xia, Z1
Koran, LM; Paiva, RS; Pallanti, S; Quercioli, L1
Bechtel, PR; Bizouard, P; Broly, F; Haffen, E; Sechter, D; Vandel, P; Vandel, S1
Koponen, H; Lehto, H; Leinonen, E; Lepola, U; Turtonen, J; Wade, A1
Ali, Z; Brady, JP1
Bagi, Z; Kecskeméti, V; Lakó-Futó, Z; Nánási, PP; Pacher, P; Ungvári, Z1
Bergstrand, A; DePierre, JW; Lundgren, B; Nässberger, L; Xia, Z1
Auclair, A; Gobert, A; Lejeune, F; Millan, MJ; Newman-Tancredi, A; Peglion, JL; Rivet, JM1
Brocco, M; Dekeyne, A; La Rochelle, CD; MacSweeny, C; Millan, MJ; Papp, M; Peglion, JL1
Bellodi, L; Cavallini, MC; Cavedini, P; Diaferia, G; Erzegovesi, S; Locatelli, M1
Albert, U; Bergesio, C; Bogetto, F; Maina, G; Pessina, E1
DePierre, JW; Karlsson, H; Nässberger, L; Ying, G1
Corda, MG; Driscoll, P; Giorgi, O; Hansson, S; Lecca, D; Piras, G1
Broocks, A; Hohagen, F; Kordon, A1
Albert, U; Bogetto, F; Maina, G; Salvi, V1
Goodman, WK; Hollander, E; Pallanti, S1
Geday, J; Hermansen, F; Rosenberg, R; Smith, DF1
Chen, JY; Chen, YA; Tao, PL; Wu, CC; Yeh, GC1
Coppinger, D; Lin, RC; Lu, Y; Maciag, D; Paul, IA; Simpson, KL; Wang, Y1
Adkins, EM; Blakely, RD; Field, JR; Henry, LK; Newman, AH; Parnas, ML; Vaughan, RA; Zou, MF1
Bajbouj, M; Danker-Hopfe, H; Gallinat, J; Hellen, F; Lang, UE; Lisanby, SH; Neu, P; Vesper, J1
Drago, F; Leggio, GM; Micale, V1
Busto, G; Di Spigno, D; Falcini, R; Salvati, L; Tundo, A1
Lombion, S; Millot, JL; Morand-Villeneuve, N1
Aigner, M; Gutierrez-Lobos, K; Hornik, K; Pirker, W; Stompe, T; Thau, K; Wenzel, T; Zettinig, G; Zitterl, W; Zitterl-Eglseer, K1
Bun'kova, KM1
Altamura, AC; Buoli, M; Dell'Osso, B; Mundo, E; Zanoni, S1
Jung, SM; Ravindran, AV; Ravindran, LN1
Carlini, M; Catena Dell'osso, M; Consoli, G; Golia, F; Marazziti, D; Mungai, F; Pfanner, C; Presta, S1
Norante, FA; Taft, AS; Yoshino, TP1
de Vos, A; Loovers, HM; van der Weide, J1
Drago, F; Leggio, GM; Micale, V; Tamburella, A1
Avesani, M; Bortolomasi, M; Manganotti, P; Minelli, A; Salvoro, B; Scassellati, C1
Bhagya, V; Raju, TR; Rao, BS; Srikumar, BN1
Huston, JP; Klingenhegel, I; Komorowski, M; Paulat, J; Sackers, J; Topic, B1
Licht, RW1
Barak, Y; Baratz-Goldstein, R; Hostovsky, A; Pick, CG; Rubovitch, V; Schreiber, S; Volis, I1
Lubszky, S; Reinhart, WH; Schulzki, T; Thöny, S1
Andersen, SE; Gislasson, G; Hansen, AH; Holm, EA; Leth-Møller, KB; Torp-Pedersen, C; Torstensson, M; Ødum, L1
Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X1
Bhave, S; Faye, A; Gawande, S; Kirpekar, V; Tadke, R1
Cuypers, E; Somers, T; Vandenbosch, M1
Aydogdu, O; Dankis, M; Tobin, G; Winder, M1
Asadi-Pooya, AA; Firouzabadi, N; Kashkooli, M; Malekpour, M; Zamiri, B1

Reviews

11 review(s) available for citalopram and clomipramine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Biochemical pharmacology of the serotonin system.
    Advances in neurology, 1986, Volume: 43

    Topics: Alanine; Brain; Citalopram; Clomipramine; Fenfluramine; Fluoxetine; Fluvoxamine; Humans; Monoamine Oxidase Inhibitors; Neurons; Oximes; p-Chloroamphetamine; Paroxetine; Piperidines; Propylamines; Receptors, Serotonin; Reserpine; Serotonin; Serotonin Antagonists; Synapses; Tetrabenazine; Zimeldine

1986
From clomipramine to mianserin: therapeutic relevance of interactions with serotonin uptake and storage, as studied in the blood platelet model.
    Acta psychiatrica Scandinavica. Supplementum, 1985, Volume: 320

    Topics: Antidepressive Agents; Biological Transport; Blood Platelets; Blood Proteins; Citalopram; Clomipramine; Cytoplasmic Granules; Depression, Chemical; Humans; Imipramine; Kinetics; Propylamines; Protein Binding; Reserpine; Serotonin

1985
The role of SSRIs in panic disorder.
    The Journal of clinical psychiatry, 1996, Volume: 57 Suppl 10

    Topics: 1-Naphthylamine; Citalopram; Clinical Trials as Topic; Clomipramine; Fluoxetine; Fluvoxamine; Humans; Panic Disorder; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome

1996
Medication treatments for panic disorder and social phobia.
    Depression and anxiety, 1998, Volume: 7, Issue:3

    Topics: Antidepressive Agents, Tricyclic; Benzamides; Benzodiazepines; Citalopram; Clinical Trials as Topic; Clomipramine; Clonazepam; Dose-Response Relationship, Drug; Female; Humans; Male; Moclobemide; Monoamine Oxidase Inhibitors; Panic Disorder; Paroxetine; Piperidines; Recurrence; Selective Serotonin Reuptake Inhibitors; Social Behavior Disorders

1998
Depression and dementia: comorbidities, identification, and treatment.
    Journal of geriatric psychiatry and neurology, 1998,Winter, Volume: 11, Issue:4

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Benzamides; Citalopram; Clomipramine; Cognition Disorders; Comorbidity; Dementia; Depression; Female; Fluoxetine; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Neuropsychological Tests; Nortriptyline; Selective Serotonin Reuptake Inhibitors; Sertraline

1998
Management of treatment resistant obsessive-compulsive disorder. Algorithms for pharmacotherapy.
    Panminerva medica, 2002, Volume: 44, Issue:2

    Topics: Algorithms; Citalopram; Clomipramine; Cognitive Behavioral Therapy; Combined Modality Therapy; Dopamine Antagonists; Drug Resistance; Drug Therapy, Combination; Humans; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors

2002
[Obsessive-compulsive disorders in general practice. How the obsessive-compulsive neurotic is revealed by skin and hair].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior Therapy; Child; Citalopram; Clomipramine; Depression; Diagnosis, Differential; Eczema; Family Practice; Female; Fluoxetine; Fluvoxamine; Humans; Male; Obsessive-Compulsive Disorder; Paroxetine; Psychotherapy; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Sertraline; Surveys and Questionnaires; Time Factors; Trichotillomania

2003
A qualitative analysis of nonresponse: management of treatment-refractory obsessive-compulsive disorder.
    The Journal of clinical psychiatry, 2004, Volume: 65 Suppl 14

    Topics: Adrenergic Uptake Inhibitors; Citalopram; Clomipramine; Deep Brain Stimulation; Electric Stimulation Therapy; Electroshock; Humans; Magnetics; Obsessive-Compulsive Disorder; Radiosurgery; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Vagus Nerve

2004
Intravenous anti-obsessive agents: a review.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:3

    Topics: Antidepressive Agents; Citalopram; Clinical Trials as Topic; Clomipramine; Drug Administration Schedule; Humans; Infusions, Intravenous; Obsessive-Compulsive Disorder; Pulse Therapy, Drug; Time Factors

2010
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
    Lancet (London, England), 2016, Aug-27, Volume: 388, Issue:10047

    Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride

2016

Trials

16 trial(s) available for citalopram and clomipramine

ArticleYear
Citalopram: clinical effect profile in comparison with clomipramine. A controlled multicenter study. Danish University Antidepressant Group.
    Psychopharmacology, 1986, Volume: 90, Issue:1

    Topics: Adolescent; Adult; Antidepressive Agents; Citalopram; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Female; Humans; Male; Propylamines; Psychiatric Status Rating Scales; Random Allocation

1986
Experiments on clinical observation and judgement in the assessment of depression: profiled videotapes and Judgement Analysis.
    Psychological medicine, 1986, Volume: 16, Issue:4

    Topics: Adult; Citalopram; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Propylamines; Psychiatry; Psychological Tests; Videotape Recording

1986
Orthostatic side effects of clomipramine and citalopram during treatment for depression.
    Psychopharmacology, 1985, Volume: 86, Issue:4

    Topics: Adult; Citalopram; Clomipramine; Depressive Disorder; Female; Humans; Hypotension, Orthostatic; Male; Middle Aged; Propylamines; Serotonin Antagonists

1985
Mortality in major affective disorder: relationship to subtype of depression. The Danish University Antidepressant Group.
    Acta psychiatrica Scandinavica, 1993, Volume: 87, Issue:5

    Topics: Adult; Aged; Citalopram; Clomipramine; Denmark; Depressive Disorder; Female; Follow-Up Studies; Humans; Male; Middle Aged; Paroxetine; Placebos; Prospective Studies; Psychiatric Status Rating Scales; Risk Factors; Sex Factors; Suicide

1993
Screening and treating depressed patients. A comparison of two controlled citalopram trials across treatment settings: hospitalized patients vs. patients treated by their family doctors. Danish University Antidepressant Group.
    Acta psychiatrica Scandinavica, 1996, Volume: 94, Issue:1

    Topics: Citalopram; Clomipramine; Depressive Disorder; Family Practice; Female; Humans; Imipramine; Male; Observer Variation; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors

1996
The effect of citalopram in panic disorder.
    The British journal of psychiatry : the journal of mental science, 1997, Volume: 170

    Topics: Adolescent; Adult; Aged; Citalopram; Clomipramine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Panic Disorder; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

1997
Fenfluramine challenge test in obsessive-compulsive disorder--first results.
    Acta medica (Hradec Kralove), 1997, Volume: 40, Issue:4

    Topics: Adult; Citalopram; Clomipramine; Double-Blind Method; Female; Fenfluramine; Humans; Male; Obsessive-Compulsive Disorder; Prolactin; Selective Serotonin Reuptake Inhibitors; Serotonin Agents

1997
Pharmacokinetic consequences of a citalopram treatment discontinuation.
    Therapeutic drug monitoring, 1999, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Citalopram; Clomipramine; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Stereoisomerism; Substance Withdrawal Syndrome

1999
Citalopram for treatment-resistant obsessive-compulsive disorder.
    European psychiatry : the journal of the Association of European Psychiatrists, 1999, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Citalopram; Clomipramine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Prospective Studies; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome

1999
Citalopram controls phobic symptoms in patients with panic disorder: randomized controlled trial.
    Journal of psychiatry & neuroscience : JPN, 2000, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Aged; Citalopram; Clomipramine; Dose-Response Relationship, Drug; Female; Humans; Long-Term Care; Male; Middle Aged; Panic Disorder; Phobic Disorders; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2000
Weight gain during long-term treatment of obsessive-compulsive disorder: a prospective comparison between serotonin reuptake inhibitors.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:10

    Topics: Adult; Ambulatory Care; Citalopram; Clomipramine; Female; Fluoxetine; Fluvoxamine; Follow-Up Studies; Humans; Male; Obesity; Obsessive-Compulsive Disorder; Paroxetine; Patient Compliance; Prospective Studies; Risk Factors; Selective Serotonin Reuptake Inhibitors; Sertraline; Weight Gain

2004
Serotonin modulation of cerebral blood flow measured with positron emission tomography (PET) in humans.
    Synapse (New York, N.Y.), 2005, Mar-15, Volume: 55, Issue:4

    Topics: Adult; Aged; Brain; Cerebral Arteries; Cerebrovascular Circulation; Citalopram; Clomipramine; Double-Blind Method; Female; Gyrus Cinguli; Humans; Hypothalamus; Injections, Intravenous; Male; Middle Aged; Oxygen Radioisotopes; Positron-Emission Tomography; Selective Serotonin Reuptake Inhibitors; Serotonin; Thalamus

2005
Motor cortex excitability after vagus nerve stimulation in major depression.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Therapy, Combination; Electric Stimulation; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Motor Cortex; Neural Conduction; Neural Inhibition; Olanzapine; Paroxetine; Psychiatric Status Rating Scales; Reboxetine; Tranylcypromine; Triazines; Vagus Nerve; Valproic Acid

2007
Intravenous augmentative citalopram versus clomipramine in partial/nonresponder depressed patients: a short-term, low dose, randomized, placebo-controlled study.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:4

    Topics: Administration, Oral; Antidepressive Agents; Citalopram; Clomipramine; Depressive Disorder, Major; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Selective Serotonin Reuptake Inhibitors

2008
Effectiveness of long-term augmentation with citalopram to clomipramine in treatment-resistant OCD patients.
    CNS spectrums, 2008, Volume: 13, Issue:11

    Topics: Adult; Citalopram; Clomipramine; Demography; Drug Resistance; Drug Synergism; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Surveys and Questionnaires; Time Factors; Young Adult

2008
Is it possible to evaluate true prophylactic efficacy of antidepressants in severely ill patients with recurrent depression? Lessons from a placebo-controlled trial. The fifth trial of the Danish University Antidepressant Group (DUAG-5).
    Journal of affective disorders, 2013, Volume: 148, Issue:2-3

    Topics: Antidepressive Agents; Citalopram; Clomipramine; Denmark; Depressive Disorder; Double-Blind Method; Feasibility Studies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Placebos; Secondary Prevention; Severity of Illness Index; Treatment Outcome

2013

Other Studies

82 other study(ies) available for citalopram and clomipramine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Synthesis of some tropane derivatives of anticipated activity on the reuptake of norepinephrine and/or serotonin.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Animals; Citalopram; Clomipramine; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoxetine; Mice; Molecular Structure; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tropanes; Yohimbine

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics

2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Protective effects of serotonin reuptake inhibitors, citalopram and clomipramine, against hippocampal CA1 neuronal damage following transient ischemia in the gerbil.
    Brain research, 1992, Sep-11, Volume: 590, Issue:1-2

    Topics: Amino Acids; Animals; Citalopram; Clomipramine; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Male; Neurons

1992
Desensitization of terminal 5-HT autoreceptors by 5-HT reuptake blockers.
    Archives of general psychiatry, 1991, Volume: 48, Issue:5

    Topics: Animals; Citalopram; Clomipramine; Clorgyline; Humans; Monoamine Oxidase Inhibitors; Obsessive-Compulsive Disorder; Rats; Receptors, Serotonin; Serotonin Antagonists

1991
Distribution of catecholamine uptake sites in human brain as determined by quantitative [3H] mazindol autoradiography.
    The Journal of comparative neurology, 1991, Feb-15, Volume: 304, Issue:3

    Topics: Aged; Benztropine; Binding, Competitive; Biological Transport; Brain Chemistry; Brain Mapping; Caudate Nucleus; Citalopram; Clomipramine; Corpus Striatum; Desipramine; Dopamine; Humans; Locus Coeruleus; Mazindol; Medulla Oblongata; Mianserin; Middle Aged; Norepinephrine; Piperazines; Pons; Substantia Nigra

1991
Serotonergic and catecholaminergic reuptake inhibitors have opposite effects on the ultrasonic isolation calls of rat pups.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1990, Volume: 3, Issue:1

    Topics: Animals; Body Temperature; Catecholamines; Citalopram; Clomipramine; Desipramine; Flumazenil; Mazindol; Motor Activity; Naltrexone; Nortriptyline; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stress, Psychological; Ultrasonics; Vocalization, Animal

1990
Dopamine-mediated increases in nigral substance P-like immunoreactivity.
    Biochemical pharmacology, 1985, Sep-01, Volume: 34, Issue:17

    Topics: Animals; Citalopram; Clomipramine; Corpus Striatum; Dopamine; Male; Methamphetamine; Nalidixic Acid; Naphthyridines; Nomifensine; Propylamines; Radioimmunoassay; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Substance P; Substantia Nigra

1985
In vitro demonstration of dopamine uptake by neostriatal serotonergic neurons of the rat.
    Neuroscience letters, 1985, Aug-16, Volume: 59, Issue:1

    Topics: Animals; Butaclamol; Citalopram; Clomipramine; Corpus Striatum; Dopamine; In Vitro Techniques; Methamphetamine; Nalidixic Acid; Naphthyridines; Propylamines; Serotonin

1985
Antinociceptive effects of serotonergic reuptake inhibitors in mice.
    Neuropharmacology, 1989, Volume: 28, Issue:12

    Topics: Alanine; Analgesics; Animals; Citalopram; Clomipramine; Desipramine; Formaldehyde; Hot Temperature; Male; Mice; Neurotransmitter Uptake Inhibitors; Serotonin Antagonists; Substance P

1989
Drug inhibition indicates a single-site model of the 5-HT uptake site/antidepressant binding site in rat and human brain.
    Psychopharmacology, 1989, Volume: 99, Issue:1

    Topics: Aged; Animals; Antidepressive Agents; Binding Sites; Brain; Citalopram; Clomipramine; Humans; In Vitro Techniques; Male; Middle Aged; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin

1989
High- and low-affinity binding of [3H]imipramine in rat hypothalamus.
    Journal of neurochemistry, 1986, Volume: 47, Issue:5

    Topics: Amitriptyline; Animals; Citalopram; Clomipramine; Cyclopropanes; Hypothalamus; Imipramine; Kinetics; Male; Milnacipran; Paroxetine; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Sodium

1986
Effect of chronic treatment with selective monoamine oxidase inhibitors and specific 5-hydroxytryptamine uptake inhibitors on [3H]paroxetine binding to cerebral cortical membranes of the rat.
    Neuropharmacology, 1987, Volume: 26, Issue:8

    Topics: Animals; Cerebral Cortex; Citalopram; Clomipramine; Clorgyline; Kinetics; Male; Membranes; Monoamine Oxidase Inhibitors; Paroxetine; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Selegiline; Serotonin

1987
Dissociation kinetics of [3H]paroxetine binding to rat brain consistent with a single-site model of the antidepressant binding/5-hydroxytryptamine uptake site.
    Journal of neurochemistry, 1988, Volume: 51, Issue:5

    Topics: Animals; Brain; Cell Membrane; Citalopram; Clomipramine; Imipramine; Kinetics; Male; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Zimeldine

1988
The mechanism by which monoamine oxidase inhibitors give rise to a non-calcium-dependent component in the depolarization-induced release of 5-HT from rat brain synaptosomes.
    British journal of pharmacology, 1988, Volume: 95, Issue:3

    Topics: Animals; Brain; Calcium; Citalopram; Clomipramine; Fluoxetine; Male; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Potassium; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes

1988
Receptor assay based on 3H-imipramine binding.
    Psychopharmacology series, 1987, Volume: 3

    Topics: Antidepressive Agents; Binding, Competitive; Blood Platelets; Chromatography, Thin Layer; Citalopram; Clomipramine; Humans; Imipramine; Propylamines; Radioligand Assay

1987
Role of the serotonin uptake carrier in the neurochemical response to methamphetamine: effects of citalopram and chlorimipramine.
    Neurochemical research, 1985, Volume: 10, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Carrier Proteins; Cerebral Cortex; Citalopram; Clomipramine; Corpus Striatum; Dopamine; Male; Methamphetamine; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tryptophan Hydroxylase

1985
Determination of citalopram, amitriptyline and clomipramine in plasma by reversed-phase high-performance liquid chromatography.
    Journal of chromatography, 1985, Feb-27, Volume: 338, Issue:1

    Topics: Amitriptyline; Chromatography, High Pressure Liquid; Citalopram; Clomipramine; Humans; Propylamines; Serotonin Antagonists; Spectrophotometry, Ultraviolet

1985
Amitriptyline and femoxetine, but not clomipramine or citalopram, antagonize hyperthermia induced by directly acting 5-hydroxytryptamine-like drugs in heat adapted rats.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:3

    Topics: Adaptation, Physiological; Amitriptyline; Animals; Body Temperature; Citalopram; Clomipramine; Dose-Response Relationship, Drug; Hot Temperature; Male; Piperazines; Piperidines; Propylamines; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists

1984
Effects of 6-methoxy-1,2,3,4-tetrahydro-beta-carboline (6-MeO-THbetaC) on audiogenic seizures in DBA/2J mice.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:1

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Benzofurans; Carbolines; Citalopram; Clomipramine; Clorgyline; Fluoxetine; Harmine; Indoles; Methoxydimethyltryptamines; Mice; Mice, Inbred DBA; N,N-Dimethyltryptamine; Pargyline; Propylamines; Quipazine; Seizures; Selegiline

1980
Antidepressants and serotonin neurons of the raphe.
    Neuropsychobiology, 1981, Volume: 7, Issue:3

    Topics: Animals; Antidepressive Agents, Tricyclic; Benzofurans; Brain Stem; Citalopram; Clomipramine; Ethers; Fluvoxamine; Imipramine; Indoles; Locus Coeruleus; Male; Microscopy, Fluorescence; Norepinephrine; Oximes; Piperidines; Propylamines; Raphe Nuclei; Rats; Receptors, Serotonin; Serotonin

1981
Behavioural profile of two potential antidepressant pyridazine derivatives including arylpiperazinyl moieties in their structure, in mice.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:2

    Topics: 5-Hydroxytryptophan; Analgesia; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Blepharoptosis; Citalopram; Clomipramine; Drug Interactions; Fluoxetine; Hypothermia; Imipramine; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Models, Molecular; Motor Activity; Naloxone; Piperazines; Pyridazines; Reserpine; Structure-Activity Relationship; Swimming; Trazodone; Yohimbine

1995
Electrophysiological activity of raphe dorsalis serotoninergic neurones in a possible model of endogenous depression.
    Neuroreport, 1995, Mar-07, Volume: 6, Issue:4

    Topics: Animals; Antidepressive Agents; Citalopram; Clomipramine; Disease Models, Animal; Male; Membrane Potentials; Neurons; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors

1995
Five fatal cases of serotonin syndrome after moclobemide-citalopram or moclobemide-clomipramine overdoses.
    Lancet (London, England), 1993, Dec-04, Volume: 342, Issue:8884

    Topics: Adult; Benzamides; Citalopram; Clomipramine; Drug Interactions; Drug Overdose; Fatal Outcome; Female; Humans; Male; Moclobemide; Monoamine Oxidase Inhibitors; Serotonin

1993
[Studies on lithium potentiation of antidepressant treatment].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1994, Volume: 14, Issue:1

    Topics: Animals; Biogenic Monoamines; Brain; Citalopram; Clomipramine; Drug Synergism; Lithium; Male; Rats; Rats, Wistar; Receptors, Serotonin

1994
The tricyclic antidepressants clomipramine and citalopram induce apoptosis in cultured human lymphocytes.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:1

    Topics: Antidepressive Agents, Tricyclic; Apoptosis; Cells, Cultured; Citalopram; Clomipramine; DNA; Humans; T-Lymphocytes

1996
Effects of chronic treatment with zimelidine and REM sleep deprivation on the regulation of raphe neuronal activity in a rat model of depression.
    Psychopharmacology, 1996, Volume: 124, Issue:3

    Topics: Animals; Citalopram; Clomipramine; Depression; Dose-Response Relationship, Drug; Electrophysiology; Male; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Sleep Deprivation; Zimeldine

1996
Antidepressant induced mania in obsessive compulsive disorder.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1996, Volume: 6, Issue:1

    Topics: Adult; Antidepressive Agents; Bipolar Disorder; Citalopram; Clomipramine; Female; Fluoxetine; Follow-Up Studies; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder

1996
Dysregulation of bcl-2, c-myc, and Fas expression during tricyclic antidepressant-induced apoptosis in human peripheral lymphocytes.
    Journal of biochemical toxicology, 1996, Volume: 11, Issue:4

    Topics: Antidepressive Agents, Tricyclic; Apoptosis; Cell Membrane; Citalopram; Clomipramine; fas Receptor; Gene Expression Regulation; Humans; Imipramine; Lymphocytes; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc

1996
Chronic treatment with antidepressants, verapamil, or lithium inhibits the serotonin-induced intracellular calcium response in individual C6 rat glioma cells.
    Life sciences, 1997, Volume: 60, Issue:11

    Topics: Animals; Antidepressive Agents; Calcium; Calcium Channel Blockers; Citalopram; Clomipramine; Drug Interactions; Glioma; Intracellular Fluid; Lithium Chloride; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Tumor Cells, Cultured; Verapamil

1997
Pica and the obsessive-compulsive spectrum disorders.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1996, Volume: 86, Issue:12 Suppl

    Topics: 1-Naphthylamine; Adolescent; Adult; Antidepressive Agents; Child; Citalopram; Clomipramine; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Pica; Sertraline; Tomography, Emission-Computed, Single-Photon

1996
Tricyclic antidepressant-induced lipidosis in human peripheral monocytes in vitro, as well as in a monocyte-derived cell line, as monitored by spectrofluorimetry and flow cytometry after staining with Nile red.
    Biochemical pharmacology, 1997, May-15, Volume: 53, Issue:10

    Topics: Antidepressive Agents, Tricyclic; Cell Line; Citalopram; Clomipramine; Flow Cytometry; Fluorescent Dyes; Humans; Imipramine; Lipidoses; Lipopolysaccharide Receptors; Microscopy, Electron; Microscopy, Fluorescence; Monocytes; Oxazines; Spectrometry, Fluorescence

1997
Density of guanine nucleotide-binding proteins in platelets of patients with major depression: increased abundance of the G alpha i2 subunit and down-regulation by antidepressant drug treatment.
    Biological psychiatry, 1997, Oct-15, Volume: 42, Issue:8

    Topics: Adult; Antidepressive Agents; Blood Platelets; Citalopram; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Down-Regulation; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Humans; Imipramine; Male; Middle Aged; Personality Inventory; Receptors, Adrenergic, alpha-2; Signal Transduction

1997
Distinct effects of imipramine on 5-hydroxytryptamine uptake mediated by the recombinant rat serotonin transporter SERT1.
    Journal of neurochemistry, 1998, Volume: 70, Issue:6

    Topics: Allosteric Site; Animals; Antidepressive Agents, Tricyclic; Biological Transport; Carrier Proteins; Cell Line; Citalopram; Clomipramine; Desipramine; Humans; Imipramine; Kidney; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sodium

1998
Response to high doses of citalopram in treatment-resistant obsessive-compulsive disorder.
    Acta psychiatrica Scandinavica, 1998, Volume: 98, Issue:5

    Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Buspirone; Citalopram; Clomipramine; Delusions; Drug Resistance; Female; Flupenthixol; Humans; Obsessive-Compulsive Disorder; Recurrence; Treatment Outcome

1998
The antidepressants imipramine, clomipramine, and citalopram induce apoptosis in human acute myeloid leukemia HL-60 cells via caspase-3 activation.
    Journal of biochemical and molecular toxicology, 1999, Volume: 13, Issue:6

    Topics: Antidepressive Agents; Apoptosis; Caspase 3; Caspases; Citalopram; Clomipramine; DNA Fragmentation; Flow Cytometry; HL-60 Cells; Humans; Imipramine; In Situ Nick-End Labeling; Leukemia, Promyelocytic, Acute; Reactive Oxygen Species

1999
Citalopram: new indication. No advantage.
    Prescrire international, 1999, Volume: 8, Issue:39

    Topics: Adult; Antidepressive Agents, Second-Generation; Citalopram; Clinical Trials as Topic; Clomipramine; Double-Blind Method; Humans; Panic Disorder; Paroxetine; Selective Serotonin Reuptake Inhibitors

1999
Citalopram: an interaction study with clomipramine in a patient heterozygous for CYP2D6 genotype.
    Pharmacopsychiatry, 1999, Volume: 32, Issue:6

    Topics: Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Citalopram; Clomipramine; Cytochrome P-450 CYP2D6; Drug Interactions; Drug Therapy, Combination; Female; Genotype; Humans; Obsessive-Compulsive Disorder; Phenotype

1999
Alprazolam, citalopram, and clomipramine for stuttering.
    Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:2

    Topics: Alprazolam; Anti-Anxiety Agents; Citalopram; Clomipramine; Drug Therapy, Combination; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Stuttering

2000
Cardiac electrophysiological effects of citalopram in guinea pig papillary muscle comparison with clomipramine.
    General pharmacology, 2000, Volume: 34, Issue:1

    Topics: Action Potentials; Animals; Antidepressive Agents, Tricyclic; Citalopram; Clomipramine; Guinea Pigs; Papillary Muscles; Selective Serotonin Reuptake Inhibitors

2000
Changes in the generation of reactive oxygen species and in mitochondrial membrane potential during apoptosis induced by the antidepressants imipramine, clomipramine, and citalopram and the effects on these changes by Bcl-2 and Bcl-X(L).
    Biochemical pharmacology, 1999, May-15, Volume: 57, Issue:10

    Topics: Antidepressive Agents; Apoptosis; bcl-X Protein; Cell Survival; Citalopram; Clomipramine; HL-60 Cells; Humans; Imipramine; Membrane Potentials; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Transfection

1999
S33005, a novel ligand at both serotonin and norepinephrine transporters: I. Receptor binding, electrophysiological, and neurochemical profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:2

    Topics: Animals; Brain Chemistry; Carrier Proteins; Citalopram; Clomipramine; Cyclohexanols; Electrophysiology; Humans; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Morpholines; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; p-Chloroamphetamine; Rats; Rats, Wistar; Reboxetine; Receptors, Adrenergic, alpha; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Symporters; Venlafaxine Hydrochloride

2001
S33005, a novel ligand at both serotonin and norepinephrine transporters: II. Behavioral profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:2

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Body Temperature; Carrier Proteins; Citalopram; Clomipramine; Cyclohexanols; Discrimination, Psychological; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Morpholines; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; p-Chloroamphetamine; Postural Balance; Rats; Rats, Wistar; Reaction Time; Reboxetine; Reserpine; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Symporters; Venlafaxine Hydrochloride

2001
Clinical predictors of drug response in obsessive-compulsive disorder.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Citalopram; Clomipramine; Drug Resistance; Female; Fluvoxamine; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Paroxetine; Predictive Value of Tests; Psychological Tests; Random Allocation; Regression Analysis; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2001
Tricyclic antidepressants prevent the differentiation of monocytes into macrophage-like cells in vitro.
    Cell biology and toxicology, 2002, Volume: 18, Issue:6

    Topics: Antidepressive Agents, Tricyclic; Antigens, Surface; Cell Differentiation; Citalopram; Clomipramine; Humans; Imipramine; Macrophages; Monocytes; Phagocytosis

2002
Differential neurochemical properties of central serotonergic transmission in Roman high- and low-avoidance rats.
    Journal of neurochemistry, 2003, Volume: 86, Issue:2

    Topics: Animals; Anxiety; Autoradiography; Avoidance Learning; Behavior, Animal; Binding, Competitive; Brain; Central Nervous System; Citalopram; Clomipramine; Depression; Fluoxetine; Male; Microdialysis; Rats; Rats, Inbred Strains; Selective Serotonin Reuptake Inhibitors; Serotonin; Species Specificity; Synaptic Transmission; Tritium

2003
Serotonin reuptake inhibitors attenuate morphine withdrawal syndrome in neonatal rats passively exposed to morphine.
    European journal of pharmacology, 2005, Apr-04, Volume: 512, Issue:1

    Topics: Animals; Animals, Newborn; Behavior, Animal; Citalopram; Clomipramine; Female; Fluoxetine; Maternal-Fetal Exchange; Morphine Dependence; Naloxone; Narcotic Antagonists; Pregnancy; Pregnancy Complications; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome

2005
Neonatal antidepressant exposure has lasting effects on behavior and serotonin circuitry.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:1

    Topics: Animals; Animals, Newborn; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antigens, Nuclear; Behavior, Animal; Body Weight; Brain; Citalopram; Clomipramine; Data Interpretation, Statistical; Female; Immunohistochemistry; Motor Activity; Nerve Tissue Proteins; Pregnancy; Rats; Rats, Long-Evans; Selective Serotonin Reuptake Inhibitors; Serotonin; Sexual Behavior, Animal; Tryptophan Hydroxylase

2006
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
    The Journal of biological chemistry, 2006, Jan-27, Volume: 281, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Amino Acid Sequence; Animals; Antidepressive Agents; Binding Sites; Binding, Competitive; Blotting, Western; Cadmium; Cell Line; Cell Membrane; Citalopram; Clomipramine; Cocaine; Cysteine; Dopamine Uptake Inhibitors; Fluoxetine; HeLa Cells; Humans; Immunoprecipitation; Isoleucine; Kinetics; LLC-PK1 Cells; Mazindol; Methionine; Mice; Models, Chemical; Molecular Sequence Data; Mutation; N-Methyl-3,4-methylenedioxyamphetamine; Nomifensine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Radiopharmaceuticals; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Species Specificity; Stereoisomerism; Substrate Specificity; Tyrosine

2006
Increased sensitivity to antidepressants of D3 dopamine receptor-deficient mice in the forced swim test (FST).
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2008, Volume: 18, Issue:4

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Male; Mice; Mice, Knockout; Motor Activity; Paroxetine; Receptors, Dopamine D3; Selective Serotonin Reuptake Inhibitors; Sertraline; Species Specificity; Swimming

2008
Addition of cognitive-behavioral therapy for nonresponders to medication for obsessive-compulsive disorder: a naturalistic study.
    The Journal of clinical psychiatry, 2007, Volume: 68, Issue:10

    Topics: Adult; Citalopram; Clomipramine; Cognitive Behavioral Therapy; Combined Modality Therapy; Cyclohexanols; Demography; Drug Resistance; Female; Fluoxetine; Fluvoxamine; Humans; Male; Obsessive-Compulsive Disorder; Paroxetine; Practice Guidelines as Topic; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome; Venlafaxine Hydrochloride

2007
Effects of anti-depressants on olfactory sensitivity in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Apr-01, Volume: 32, Issue:3

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Choice Behavior; Citalopram; Clomipramine; Discrimination, Psychological; Female; Maze Learning; Mice; Odorants; Olfactory Pathways; Time Factors

2008
Changes in thalamus-hypothalamus serotonin transporter availability during clomipramine administration in patients with obsessive-compulsive disorder.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:13

    Topics: Adult; Binding, Competitive; Citalopram; Clomipramine; Down-Regulation; Female; Humans; Hypothalamus; Iodine Radioisotopes; Male; Middle Aged; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Thalamus; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Young Adult

2008
[Efficacy and tolerability of clomipramine, pirlindole and escitalopram in the treatment of neurotic level depression].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2008, Volume: 108, Issue:3

    Topics: Adolescent; Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Carbazoles; Citalopram; Clomipramine; Data Interpretation, Statistical; Depressive Disorder; Female; Humans; International Classification of Diseases; Male; Middle Aged; Remission Induction; Selective Serotonin Reuptake Inhibitors; Time Factors

2008
The identification of inhibitors of Schistosoma mansoni miracidial transformation by incorporating a medium-throughput small-molecule screen.
    Experimental parasitology, 2010, Volume: 125, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Anthelmintics; Benzophenanthridines; Calcimycin; Calcium Channel Blockers; Citalopram; Clomipramine; Colforsin; Cyclic AMP; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Immunohistochemistry; Mice; Schistosoma mansoni; Tetradecanoylphorbol Acetate; Triflupromazine

2010
Association between CYP2C19*17 and metabolism of amitriptyline, citalopram and clomipramine in Dutch hospitalized patients.
    The pharmacogenomics journal, 2011, Volume: 11, Issue:5

    Topics: Adolescent; Adult; Aged; Alleles; Amitriptyline; Aryl Hydrocarbon Hydroxylases; Biomarkers, Pharmacological; Citalopram; Clomipramine; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Dose-Response Relationship, Drug; Female; Genetic Association Studies; Humans; Male; Middle Aged; Netherlands; Polymorphism, Genetic

2011
The beta3 adrenoceptor agonist, amibegron (SR58611A) counteracts stress-induced behavioral and neurochemical changes.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010, Volume: 20, Issue:10

    Topics: Adrenergic beta-3 Receptor Agonists; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; bcl-2-Associated X Protein; Behavior, Animal; Brain-Derived Neurotrophic Factor; Citalopram; Clomipramine; Cyclic AMP Response Element-Binding Protein; Depression; Hippocampus; Male; Proto-Oncogene Proteins c-bcl-2; Rats; Stress, Psychological; Swimming; Tetrahydronaphthalenes

2010
Effects of intravenous antidepressant drugs on the excitability of human motor cortex: a study with paired magnetic stimulation on depressed patients.
    Brain stimulation, 2010, Volume: 3, Issue:1

    Topics: Antidepressive Agents, Tricyclic; Citalopram; Clomipramine; Depressive Disorder, Major; Evoked Potentials, Motor; Humans; Injections, Intravenous; Motor Cortex; Placebos; Selective Serotonin Reuptake Inhibitors; Transcranial Magnetic Stimulation

2010
Chronic escitalopram treatment restores spatial learning, monoamine levels, and hippocampal long-term potentiation in an animal model of depression.
    Psychopharmacology, 2011, Volume: 214, Issue:2

    Topics: Acetylcholinesterase; Analysis of Variance; Animals; Animals, Newborn; Antidepressive Agents, Second-Generation; Biogenic Monoamines; Citalopram; Clomipramine; Depression; Disease Models, Animal; Drug Administration Schedule; Feeding Behavior; Hippocampus; Learning; Long-Term Potentiation; Male; Maze Learning; Memory; Motor Activity; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Swimming; Time Factors

2011
Distance from source of reward as a marker for extinction-induced "despair": modulation by the antidepressants clomipramine and citalopram.
    Neuroscience, 2012, Oct-25, Volume: 223

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Citalopram; Clomipramine; Conditioning, Operant; Depressive Disorder, Major; Disease Models, Animal; Exploratory Behavior; Extinction, Psychological; Male; Rats; Rats, Wistar; Reaction Time; Reward; Time Factors

2012
Interaction of different antidepressants with acute and chronic methadone in mice, and possible clinical implications.
    Journal of molecular neuroscience : MN, 2014, Volume: 52, Issue:4

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Citalopram; Clomipramine; Cyclohexanols; Desipramine; Drug Interactions; Fluvoxamine; Male; Methadone; Mice; Mice, Inbred ICR; Morpholines; Nociception; Pain Threshold; Reboxetine; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride

2014
Interaction of injectable neurotropic drugs with the red cell membrane.
    Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:7

    Topics: Central Nervous System Agents; Chlorpromazine; Citalopram; Clomipramine; Clonazepam; Diazepam; Erythrocytes; Humans; Injections; Levetiracetam; Microscopy, Electron, Scanning; Neurotransmitter Agents; Phenobarbital; Phenytoin; Piracetam; Valproic Acid

2014
Antidepressants and the risk of hyponatremia: a Danish register-based population study.
    BMJ open, 2016, 05-18, Volume: 6, Issue:5

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Citalopram; Clomipramine; Denmark; Duloxetine Hydrochloride; Female; Humans; Hyponatremia; Incidence; Male; Mianserin; Middle Aged; Mirtazapine; Registries; Retrospective Studies; Risk Factors; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Sodium; Venlafaxine Hydrochloride

2016
Obsession of pregnancy: Does it exist?
    Asian journal of psychiatry, 2017, Volume: 29

    Topics: Attitude to Health; Citalopram; Clomipramine; Clonazepam; Cognitive Behavioral Therapy; Depressive Disorder; Diagnosis, Differential; Female; Fluoxetine; GABA Modulators; Humans; Middle Aged; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors

2017
Distribution of clomipramine, citalopram, midazolam, and metabolites in skeletal tissue after chronic dosing in rats.
    Drug testing and analysis, 2019, Volume: 11, Issue:7

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Bone and Bones; Chromatography, High Pressure Liquid; Citalopram; Clomipramine; Limit of Detection; Male; Midazolam; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2019
Acute Inhibitory Effects of Antidepressants on Lacrimal Gland Secretion in the Anesthetized Rat.
    Investigative ophthalmology & visual science, 2021, 06-01, Volume: 62, Issue:7

    Topics: Animals; Antidepressive Agents; Cholinergic Antagonists; Citalopram; Clomipramine; Dry Eye Syndromes; Evoked Potentials, Visual; Lacrimal Apparatus; Methacholine Chloride; Miotics; Rats; Tears

2021
FKBP5 blockade may provide a new horizon for the treatment of stress-associated disorders: An in-silico study.
    Epilepsia open, 2023, Volume: 8, Issue:2

    Topics: Citalopram; Clomipramine; Duloxetine Hydrochloride; Fluoxetine; Humans; Sertraline; United States

2023