cisapride and tegaserod

cisapride has been researched along with tegaserod in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.52)18.2507
2000's12 (57.14)29.6817
2010's5 (23.81)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Fischmeister, R; Langlois, M1
Armstrong, SR; Beattie, DT; Choi, SK; Fatheree, PR; Gendron, RA; Goldblum, A; Humphrey, PP; Long, DD; Marquess, DG; McKinnell, RM; Shaw, JP; Smith, JA; Turner, SD; Vickery, RG1
Armstrong, SR; Beattie, DT; Fatheree, PR; Long, DD; Marquess, DG; McKinnell, RM; Shaw, JP; Vickery, RG1
Drici, MD; Ebert, SN; Liu, XK; Rodriguez, I; Wang, WX; Whitfield, BH; Woosley, RL1
Akkermans, LM; Briejer, MR; Lefebvre, RA; Prins, NH; Schuurkes, JA; Van Haselen, JF1
Washabau, RJ1
Petroianu, GA1
Olden, KW1
Gremlich, HU; Kinzy, W; Kneuer, R; Martínez, V; Pfannkuche, HJ; Rudin, M; Weber, E1
Kamm, MA1
Hanauer, SB1
Armstrong, SR; Beattie, DT; Humphrey, PP; Marquess, D; Sandlund, C; Shaw, JP; Smith, JA; Taylor, JA1
Beattie, DT; Humphrey, PP; Marquess, D; Shaw, JP; Smith, JA; Vickery, RG1
Eslick, GD; Kalantar, JS; Kan, AE; Shim, LS1
Boyle, G; Crowell, K; Mounsey, A1
Chai, W; Chan, KY; Danser, AH; de Maeyer, JH; de Vries, R; MaassenVanDenBrink, A; Saxena, PR; Schuurkes, JA; van den Bogeardt, AJ; Villalón, CM1
Camilleri, M; Chang, L; Chey, WD; De Maeyer, JH; Galligan, JJ; Lacy, BE; Müller-Lissner, S; Quigley, EM; Schuurkes, J; Stanghellini, V; Tack, J1
Amagasu, SM; Beattie, DT; Ero, MP; Higgins, DL; Hopkins, A; Kersey, K; Smith, JA; Vickery, RG1
Bollegala, NP; Khanna, R; Leontiadis, GI; Moayyedi, P; Pittayanon, R; Yuan, Y1
Fujio, Y; Hamatani, T; Kaji, Y; Kakuyama, H; Kawai, H; Noda, N; Takagaki, T; Yodo, Y1
Aquino, I; Coello, M; Ocampo, L1

Reviews

5 review(s) available for cisapride and tegaserod

ArticleYear
5-HT4 receptor ligands: applications and new prospects.
    Journal of medicinal chemistry, 2003, Jan-30, Volume: 46, Issue:3

    Topics: Animals; Benzamides; Benzimidazoles; Benzoates; Binding Sites; Cardiovascular Physiological Phenomena; Central Nervous System; Digestive System Physiological Phenomena; Humans; Indoles; Ketones; Ligands; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2003
Gastrointestinal motility disorders and gastrointestinal prokinetic therapy.
    The Veterinary clinics of North America. Small animal practice, 2003, Volume: 33, Issue:5

    Topics: Animals; Benzofurans; Cisapride; Dog Diseases; Dogs; Gastrointestinal Agents; Gastrointestinal Motility; Indoles; Intestinal Diseases; Motilin

2003
Pharmacological treatment of irritable bowel syndrome--from concept to sales.
    The European journal of surgery. Supplement. : = Acta chirurgica. Supplement, 2002, Issue:587

    Topics: Antidepressive Agents; Benzofurans; Carbolines; Cisapride; Constipation; Drug Industry; Gastrointestinal Agents; Humans; Indoles; Irritable Bowel Syndrome; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists

2002
Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders.
    Alimentary pharmacology & therapeutics, 2012, Volume: 35, Issue:7

    Topics: Cardiovascular Diseases; Cisapride; Gastrointestinal Agents; Gastrointestinal Diseases; Humans; Indoles; Randomized Controlled Trials as Topic; Serotonin 5-HT4 Receptor Agonists

2012
Prokinetics for functional dyspepsia.
    The Cochrane database of systematic reviews, 2018, Oct-18, Volume: 10

    Topics: Benzamides; Benzyl Compounds; Cisapride; Domperidone; Dyspepsia; Erythromycin; Gastrointestinal Agents; Humans; Indoles; Morpholines; Numbers Needed To Treat; Quality of Life; Randomized Controlled Trials as Topic; Thiazoles

2018

Trials

2 trial(s) available for cisapride and tegaserod

ArticleYear
Thorough QT/QTc Study Shows That a Novel 5-HT
    Clinical pharmacology in drug development, 2020, Volume: 9, Issue:8

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Arrhythmias, Cardiac; Asian People; Benzamides; Case-Control Studies; Cisapride; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Humans; Indoles; Irritable Bowel Syndrome; Long QT Syndrome; Male; Morpholines; Moxifloxacin; Piperidines; Placebos; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists

2020
Comparative Efficacy of the Prokinetic Effects of Cisapride and Tegaserod in Equines.
    Journal of equine veterinary science, 2020, Volume: 92

    Topics: Animals; Cisapride; Defecation; Horses; Indoles; Muscle, Smooth

2020

Other Studies

14 other study(ies) available for cisapride and tegaserod

ArticleYear
A multivalent approach to the design and discovery of orally efficacious 5-HT4 receptor agonists.
    Journal of medicinal chemistry, 2009, Sep-10, Volume: 52, Issue:17

    Topics: Administration, Oral; Animals; Binding Sites; Biological Availability; Cell Line; Dogs; Drug Design; Gastrointestinal Diseases; Humans; Male; Movement; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Substrate Specificity

2009
Discovery of TD-8954, a clinical stage 5-HT(4) receptor agonist with gastrointestinal prokinetic properties.
    Bioorganic & medicinal chemistry letters, 2013, Jul-15, Volume: 23, Issue:14

    Topics: Animals; Benzimidazoles; Crystallography, X-Ray; Dogs; Drug Evaluation, Preclinical; Guinea Pigs; Half-Life; Intestinal Mucosa; Male; Molecular Conformation; Piperidines; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists

2013
Comparison of tegaserod (HTF 919) and its main human metabolite with cisapride and erythromycin on cardiac repolarization in the isolated rabbit heart.
    Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:1

    Topics: Animals; Cisapride; Dose-Response Relationship, Drug; Electrocardiography; Erythromycin; Female; Gastrointestinal Agents; Heart; In Vitro Techniques; Indoles; Perfusion; Rabbits

1999
Pharmacological characterization of 5-HT4 receptors mediating relaxation of canine isolated rectum circular smooth muscle.
    British journal of pharmacology, 1999, Volume: 127, Issue:6

    Topics: 5-Methoxytryptamine; Animals; Cisapride; Colon; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Indoles; Male; Muscle Relaxation; Muscle, Smooth; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Rectum; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides

1999
Chronic idiopathic singultus: is there life after cisapride?
    The New Zealand medical journal, 2004, Jan-30, Volume: 117, Issue:1188

    Topics: Acetates; Amines; Anticonvulsants; Cisapride; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Agents; Hiccup; Humans; Indoles; Phosphodiesterase Inhibitors; Serotonin Receptor Agonists

2004
Therapy for irritable bowel syndrome.
    The New England journal of medicine, 2004, Mar-18, Volume: 350, Issue:12

    Topics: Antidepressive Agents; Cisapride; Female; Humans; Indoles; Irritable Bowel Syndrome; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists

2004
Noninvasive assessment of gastric emptying by near-infrared fluorescence reflectance imaging in mice: pharmacological validation with tegaserod, cisapride, and clonidine.
    Molecular imaging, 2004, Volume: 3, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Carbocyanines; Cisapride; Clonidine; Fluorescence; Fluorescent Dyes; Gastric Emptying; Indoles; Male; Mice; Mice, Inbred BALB C; Serotonin Receptor Agonists

2004
Moving ahead or falling behind?
    Nature clinical practice. Gastroenterology & hepatology, 2007, Volume: 4, Issue:6

    Topics: Cisapride; Constipation; Domperidone; Gastrointestinal Agents; Gastrointestinal Diseases; Gastrointestinal Motility; Humans; Indoles; Piperidines; Risk Assessment

2007
The in vivo gastrointestinal activity of TD-5108, a selective 5-HT(4) receptor agonist with high intrinsic activity.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 378, Issue:1

    Topics: Administration, Oral; Animals; Azabicyclo Compounds; Benzamides; Cisapride; Colon; Dogs; Dose-Response Relationship, Drug; Esophagus; Female; Gastrointestinal Transit; Guinea Pigs; Indoles; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists

2008
The in vitro pharmacological profile of TD-5108, a selective 5-HT(4) receptor agonist with high intrinsic activity.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 378, Issue:1

    Topics: Animals; Azabicyclo Compounds; Benzamides; Cell Line; Cisapride; Colon; Cyclic AMP; Esophagus; Ether-A-Go-Go Potassium Channels; Guinea Pigs; Humans; Indoles; Kidney; Morpholines; Protein Binding; Rats; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists

2008
A case of chronic intestinal pseudo-obstruction secondary to primary visceral myopathy.
    Nature clinical practice. Gastroenterology & hepatology, 2008, Volume: 5, Issue:10

    Topics: Adolescent; Biopsy; Chronic Disease; Cisapride; Female; Gastrointestinal Agents; Humans; Indoles; Intestinal Pseudo-Obstruction; Parenteral Nutrition, Total; Serotonin Receptor Agonists; Tomography, X-Ray Computed

2008
Clinical inquiries: what is the role of prokinetic agents for constipation?
    The Journal of family practice, 2009, Volume: 58, Issue:4

    Topics: Cisapride; Constipation; Gastrointestinal Agents; Humans; Indoles

2009
Inotropic effects of prokinetic agents with 5-HT(4) receptor agonist actions on human isolated myocardial trabeculae.
    Life sciences, 2012, Apr-09, Volume: 90, Issue:13-14

    Topics: 5-Methoxytryptamine; Adolescent; Adult; Aged; Benzofurans; Calcium Channels; Child; Cisapride; Female; Gastrointestinal Agents; Heart Atria; Heart Ventricles; Humans; Indoles; Male; Middle Aged; Muscle Contraction; Myocardium; Pyridines; Quinuclidines; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Agonists; Serotonin Antagonists; Sulfonamides; Young Adult

2012
An in vitro investigation of the cardiovascular effects of the 5-HT(4) receptor selective agonists, velusetrag and TD-8954.
    Vascular pharmacology, 2013, Volume: 58, Issue:1-2

    Topics: Adult; Animals; Azabicyclo Compounds; Benzimidazoles; CHO Cells; Cisapride; Coronary Vessels; Cricetinae; Cricetulus; Dogs; Ether-A-Go-Go Potassium Channels; Female; Humans; In Vitro Techniques; Indoles; Male; Middle Aged; Piperidines; Platelet Aggregation; Serotonin 5-HT4 Receptor Agonists; Swine

2013