cisapride and norcisapride

cisapride has been researched along with norcisapride in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's5 (62.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bares, R; Dakshinamurty, KV; Gladziwa, U; Ittel, TH; Klotz, U; Seiler, KU; Sieberth, HG1
Cisternino, S; Saulnier, JL; Schlatter, J1
Addison, RS; Duffy, SL; Mathers, SR1
Bailey, DG; Bend, JR; Dresser, GK; Freeman, DJ; Munoz, C; Offman, EM1
Gotschall, RR; Kearns, GL; Leeder, JS; Pearce, RE1
Abdel-Rahman, SM; Bertino, JS; Kashuba, AD; Kearns, GL; Khan, IS; Leeder, JS; Lowry, JA; Nafziger, AN; Schuetz, EG; van den Anker, JN1
Kearns, GL; Knight, GR; Robinson, PK; van den Anker, JN; Ward, RM; Wilson, JT; Wilson-Costello, D1
Barberich, TJ; Hewitt, MC; Shao, L; Wang, F1

Trials

3 trial(s) available for cisapride and norcisapride

ArticleYear
Red wine-cisapride interaction: comparison with grapefruit juice.
    Clinical pharmacology and therapeutics, 2001, Volume: 70, Issue:1

    Topics: Adult; Area Under Curve; Beverages; Cisapride; Citrus; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Food-Drug Interactions; Gastrointestinal Agents; Humans; Male; Mixed Function Oxygenases; Reference Values; Wine

2001
Cisapride: a potential model substrate to assess cytochrome P4503A4 activity in vivo.
    Clinical pharmacology and therapeutics, 2003, Volume: 73, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Chromatography, High Pressure Liquid; Cisapride; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Humans; Infusions, Intravenous; LLC-PK1 Cells; Male; Mass Spectrometry; Midazolam; Middle Aged; Models, Biological; Regression Analysis; Swine

2003
Cisapride disposition in neonates and infants: in vivo reflection of cytochrome P450 3A4 ontogeny.
    Clinical pharmacology and therapeutics, 2003, Volume: 74, Issue:4

    Topics: Area Under Curve; Chromatography, High Pressure Liquid; Cisapride; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Gastrointestinal Agents; Half-Life; Humans; Infant; Infant, Newborn; Male; Metabolic Clearance Rate

2003

Other Studies

5 other study(ies) available for cisapride and norcisapride

ArticleYear
Pharmacokinetics and pharmacodynamics of cisapride in patients undergoing hemodialysis.
    Clinical pharmacology and therapeutics, 1991, Volume: 50, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Chromatography, Gas; Chromatography, High Pressure Liquid; Cisapride; Female; Gastric Emptying; Humans; Kidney Failure, Chronic; Male; Middle Aged; Monitoring, Physiologic; Piperidines; Renal Dialysis

1991
Determination of cisapride and norcisapride in human plasma using high-performance liquid chromatography with ultraviolet detection.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, Sep-04, Volume: 714, Issue:2

    Topics: Chromatography, High Pressure Liquid; Cisapride; Gastrointestinal Agents; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

1998
A simple high-performance liquid chromatography assay for the major cisapride metabolite, norcisapride, in human urine.
    Journal of chromatographic science, 1999, Volume: 37, Issue:3

    Topics: Chromatography, High Pressure Liquid; Cisapride; Humans; Indicators and Reagents; Reproducibility of Results

1999
Cytochrome P450 Involvement in the biotransformation of cisapride and racemic norcisapride in vitro: differential activity of individual human CYP3A isoforms.
    Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:12

    Topics: Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Biotransformation; Chromatography, High Pressure Liquid; Cisapride; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Isoenzymes; Male; Mass Spectrometry; Oxidoreductases, N-Demethylating; Stereoisomerism

2001
mu-Opioid/5-HT4 dual pharmacologically active agents-efforts towards an effective opioid analgesic with less GI and respiratory side effects (Part I).
    Bioorganic & medicinal chemistry letters, 2009, Oct-01, Volume: 19, Issue:19

    Topics: Analgesics, Opioid; Cisapride; Gastrointestinal Transit; Humans; Metoclopramide; Receptors, Opioid, mu; Receptors, Serotonin, 5-HT4; Respiratory System; Serotonin 5-HT4 Receptor Agonists; Stereoisomerism; Tramadol

2009