cisapride and mosapride

cisapride has been researched along with mosapride in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (19.35)18.2507
2000's19 (61.29)29.6817
2010's6 (19.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karasawa, T; Kato, S; Kon, T; Matsumoto, J; Morie, T; Yoshida, N1
Bender, E; Gommeren, W; Jurzak, M; Leysen, J; Luyten, W; Pindon, A; van Oers, I; Verhasselt, P; Zhang, YB1
Fischmeister, R; Langlois, M1
Fujiwara, I; Harada, H; Hirokawa, Y; Kato, S; Suzuki, K; Yoshida, N; Yoshikawa, T1
Imai, YN; Oiki, S; Ryu, S1
Sen, S; Sinha, N1
Ito, T; Itoh, Z; Karasawa, T; Yoshida, N1
Ito, T; Kii, Y2
Amos, GJ; Andersson, B; Carlsson, L; Drews, L; Duker, G; Wadstedt, G1
Kamato, T; Miyata, K; Nagakura, Y; Yamano, M1
Kakigami, T; Kataoka, T; Tsukamoto, K; Usui, T1
Douya, R; Mushiroda, T; Nagata, O; Takahara, E1
Ito, T; Kii, Y; Mizuki, Y; Nakatsuji, K; Nose, I; Yabuuchi, M1
Baró, I; Bouyssou, T; Escande, D; Potet, F1
Hongo, M; Satake, M1
Dkhar, SA; Shashindran, CH; Shewade, DG; Suchitra, AD1
Fujii, H; Kadowaki, M; Kojima, Y; Nakagawa, T; Nakajima, Y; Shimatani, H; Takaki, M1
Cange, L; Finizia, C; Lundell, L; Ruth, M1
Chayama, K; Haruma, K; Hiyama, T; Ito, M; Kamada, T; Kusunoki, H; Matsuo, K; Nishi, N; Tanaka, S; Yoshihara, M1
Chayama, K; Haruma, K; Hiyama, T; Ito, M; Kamada, T; Kusunoki, H; Matsuo, K; Tanaka, S; Yoshihara, M1
Kawatsu, R; Kohmura, Y; Toga, T1
Armstrong, SR; Beattie, DT; Humphrey, PP; Marquess, D; Sandlund, C; Shaw, JP; Smith, JA; Taylor, JA1
Beattie, DT; Humphrey, PP; Marquess, D; Shaw, JP; Smith, JA; Vickery, RG1
Nandurkar, S1
Inokuma, H; Okamura, K; Sasaki, N; Yamada, H; Yamada, M1
Eta, R; Furuta, S; Hori, Y; Itoh, Z; Kawabata, Y; Matsumura, T; Matsunaga, Y; Tack, J; Takei, M; Tanaka, T; Ueki, S; Yoshida, K; Yoshii, K; Yoshinaga, K1
Hahn, SJ; Sung, KW1
Chen, WJ; Dai, YK; Hu, L; Huang, MX; Li, DY; Li, RL; Ou-Yang, J; Zhang, YZ1
Bollegala, NP; Khanna, R; Leontiadis, GI; Moayyedi, P; Pittayanon, R; Yuan, Y1
Choi, TY; Kim, KH; Kim, TH; Lee, MS1

Reviews

7 review(s) available for cisapride and mosapride

ArticleYear
5-HT4 receptor ligands: applications and new prospects.
    Journal of medicinal chemistry, 2003, Jan-30, Volume: 46, Issue:3

    Topics: Animals; Benzamides; Benzimidazoles; Benzoates; Binding Sites; Cardiovascular Physiological Phenomena; Central Nervous System; Digestive System Physiological Phenomena; Humans; Indoles; Ketones; Ligands; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2003
[Prokinetics of gastrointestinal system; its newer aspects with regard to motillity stimulants].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 2

    Topics: Acetylcholine; Benzamides; Cisapride; Domperidone; Dyspepsia; Gastrointestinal Agents; Gastrointestinal Motility; Humans; Metoclopramide; Morpholines; Stimulation, Chemical; Trimebutine

2002
Meta-analysis of the effects of prokinetic agents in patients with functional dyspepsia.
    Journal of gastroenterology and hepatology, 2007, Volume: 22, Issue:3

    Topics: Benzamides; Benzyl Compounds; Cisapride; Domperidone; Dopamine Antagonists; Dyspepsia; Gastrointestinal Agents; Humans; Metoclopramide; Morpholines; Trimebutine

2007
Treatment of functional dyspepsia with serotonin agonists: a meta-analysis of randomized controlled trials.
    Journal of gastroenterology and hepatology, 2007, Volume: 22, Issue:10

    Topics: Benzamides; Cisapride; Data Interpretation, Statistical; Dopamine Antagonists; Dyspepsia; Gastrointestinal Agents; Humans; Morpholines; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Trimebutine

2007
Systematic review and meta-analysis of traditional Chinese medicine in the treatment of constipation-predominant irritable bowel syndrome.
    PloS one, 2017, Volume: 12, Issue:12

    Topics: Benzamides; Cisapride; Constipation; Humans; Irritable Bowel Syndrome; Medicine, Chinese Traditional; Morpholines; Odds Ratio; Randomized Controlled Trials as Topic

2017
Prokinetics for functional dyspepsia.
    The Cochrane database of systematic reviews, 2018, Oct-18, Volume: 10

    Topics: Benzamides; Benzyl Compounds; Cisapride; Domperidone; Dyspepsia; Erythromycin; Gastrointestinal Agents; Humans; Indoles; Morpholines; Numbers Needed To Treat; Quality of Life; Randomized Controlled Trials as Topic; Thiazoles

2018
Acupuncture for symptomatic gastroparesis.
    The Cochrane database of systematic reviews, 2018, 12-18, Volume: 12

    Topics: Acupuncture Therapy; Benzamides; Cimetidine; Cisapride; Diabetes Complications; Domperidone; Gastrointestinal Agents; Gastroparesis; Histamine H2 Antagonists; Humans; Morpholines; Randomized Controlled Trials as Topic

2018

Trials

1 trial(s) available for cisapride and mosapride

ArticleYear
The effect of mosapride on oesophageal motor function and acid reflux in patients with gastro-oesophageal reflux disease.
    European journal of gastroenterology & hepatology, 2003, Volume: 15, Issue:10

    Topics: Adult; Aged; Benzamides; Cisapride; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Esophagus; Female; Gastroesophageal Reflux; Gastrointestinal Agents; Humans; Hydrogen-Ion Concentration; Male; Manometry; Middle Aged; Morpholines; Peristalsis; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Agonists

2003

Other Studies

23 other study(ies) available for cisapride and mosapride

ArticleYear
Novel benzamides as selective and potent gastrokinetic agents. 2. Synthesis and structure-activity relationships of 4-amino-5-chloro-2-ethoxy-N-[[4-(4-fluorobenzyl)-2- morpholinyl]methyl] benzamide citrate (AS-4370) and related compounds.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:2

    Topics: Animals; Benzamides; Chemical Phenomena; Chemistry; Cisapride; Dogs; Gastric Emptying; Gastrointestinal Agents; Male; Metoclopramide; Mice; Morpholines; Piperidines; Rats; Serotonin Antagonists; Structure-Activity Relationship

1991
Structure of the human serotonin 5-HT4 receptor gene and cloning of a novel 5-HT4 splice variant.
    Journal of neurochemistry, 2000, Volume: 74, Issue:2

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; COS Cells; DNA, Recombinant; Genetic Variation; Humans; Molecular Sequence Data; Protein Isoforms; Receptors, Serotonin; RNA, Messenger; Tissue Distribution

2000
Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity.
    Journal of medicinal chemistry, 2003, Feb-27, Volume: 46, Issue:5

    Topics: Animals; Antiemetics; Azepines; Brain; Crystallography, X-Ray; Dogs; Dopamine Antagonists; Ferrets; In Vitro Techniques; Models, Molecular; Pyridines; Rats; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Stereoisomerism; Structure-Activity Relationship

2003
Docking model of drug binding to the human ether-à-go-go potassium channel guided by tandem dimer mutant patch-clamp data: a synergic approach.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Amino Acid Sequence; Binding Sites; Cell Line; Cisapride; Dimerization; Ether-A-Go-Go Potassium Channels; Humans; Models, Molecular; Molecular Sequence Data; Mutation; Patch-Clamp Techniques; Piperidines; Pyridines; Sequence Homology, Amino Acid; Terfenadine

2009
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
AS-4370, a new gastrokinetic agent, enhances upper gastrointestinal motor activity in conscious dogs.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:2

    Topics: Animals; Benzamides; Cisapride; Dogs; Duodenum; Female; Gastrointestinal Agents; Gastrointestinal Motility; Jejunum; Male; Metoclopramide; Morpholines; Piperidines; Pyloric Antrum; Serotonin Antagonists

1991
Effects of 5-HT4-receptor agonists, cisapride, mosapride citrate, and zacopride, on cardiac action potentials in guinea pig isolated papillary muscles.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:5

    Topics: Action Potentials; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Anti-Arrhythmia Agents; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Electric Stimulation; Electrocardiography; Guinea Pigs; Heart; In Vitro Techniques; Male; Microelectrodes; Morpholines; Muscle, Smooth, Vascular; Papillary Muscles; Piperidines; Prazosin; Quaternary Ammonium Compounds; Serotonin Antagonists; Serotonin Receptor Agonists; Sympathetic Nervous System

1997
Electrophysiological characterization of the prokinetic agents cisapride and mosapride in vivo and in vitro: implications for proarrhythmic potential?
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:1

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Benzamides; Cisapride; Guinea Pigs; Heart; In Vitro Techniques; Long QT Syndrome; Male; Morpholines; Piperidines; Purkinje Fibers; Rabbits; Structure-Activity Relationship

1997
Effects of gastroprokinetic agents on gastroparesis in streptozotocin-induced diabetic rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:1

    Topics: Animals; Benzamides; Benzimidazoles; Blood Glucose; Cisapride; Diabetes Mellitus, Experimental; Gastric Emptying; Gastrointestinal Motility; Gastroparesis; Granisetron; Male; Morpholines; Ondansetron; Piperidines; Pyrroles; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Vagotomy

1997
Synthesis and structure-activity relationship of 3-Substituted benzamide, benzo [b]furan-7-carboxamide, 2,3-dihydrobenzo[b]furan-77-carboxamide, and indole-5-carboxamide derivatives as selective serotonin 5-HT4 receptor agonists.
    Chemical & pharmaceutical bulletin, 1998, Volume: 46, Issue:1

    Topics: Animals; Benzamides; Benzofurans; Brain; Cisapride; Indoles; Morpholines; Piperidines; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Receptor Agonists; Structure-Activity Relationship

1998
The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: comparison with cisapride and mosapride citrate.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:10

    Topics: Administration, Oral; Animals; Antiemetics; Area Under Curve; Benzamides; Benzyl Compounds; Cimetidine; Cisapride; Clarithromycin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Stability; Erythromycin; Hot Temperature; Isoenzymes; Ketoconazole; Male; Microsomes, Liver; Mixed Function Oxygenases; Morpholines; Oxygen; Oxygenases; Rats; Rats, Sprague-Dawley

2000
Effects of 5-HT(4) receptor agonists, cisapride and mosapride citrate on electrocardiogram in anaesthetized rats and guinea-pigs and conscious cats.
    Pharmacology & toxicology, 2001, Volume: 89, Issue:2

    Topics: Anesthesia; Animals; Benzamides; Cats; Cisapride; Consciousness; Dose-Response Relationship, Drug; Electrocardiography; Female; Guinea Pigs; Heart Rate; Heart Ventricles; Long QT Syndrome; Male; Morpholines; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists

2001
Gastrointestinal prokinetic drugs have different affinity for the human cardiac human ether-à-gogo K(+) channel.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Benzamides; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Cation Transport Proteins; Cisapride; DNA-Binding Proteins; Electrophysiology; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Gastrointestinal Agents; Glycosaminoglycans; Humans; Morpholines; Potassium Channels; Potassium Channels, Voltage-Gated; Recombinant Proteins; Serotonin Antagonists; Trans-Activators; Transcriptional Regulator ERG

2001
Drug-induced ventricular tachyarrhythmia in isolated rabbit hearts with atrioventricular block.
    Pharmacology & toxicology, 2002, Volume: 90, Issue:5

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzamides; Cisapride; Dimethyl Sulfoxide; Disease Models, Animal; Electrocardiography; Heart Block; In Vitro Techniques; Magnesium Sulfate; Male; Morpholines; Potassium; Rabbits; Solvents; Sotalol; Tachycardia

2002
Relative efficacy of some prokinetic drugs in morphine-induced gastrointestinal transit delay in mice.
    World journal of gastroenterology, 2003, Volume: 9, Issue:4

    Topics: Animals; Benzamides; Cisapride; Domperidone; Drug Interactions; Erythromycin; Female; Gastric Emptying; Gastrointestinal Transit; Male; Metoclopramide; Mice; Morphine; Morpholines

2003
A 5-HT4 agonist mosapride enhances rectorectal and rectoanal reflexes in guinea pigs.
    American journal of physiology. Gastrointestinal and liver physiology, 2003, Volume: 285, Issue:2

    Topics: Anal Canal; Animals; Benzamides; Cisapride; Guinea Pigs; Indoles; Injections, Intravenous; Male; Morpholines; Muscle Contraction; Muscle Relaxation; Receptors, Serotonin; Rectum; Reflex; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Transducers, Pressure

2003
The 5-HT(4) agonists cisapride, mosapride, and CJ-033466, a Novel potent compound, exhibit different human ether-a-go-go-related gene (hERG)-blocking activities.
    Journal of pharmacological sciences, 2007, Volume: 105, Issue:2

    Topics: Aminopyridines; Arrhythmias, Cardiac; Benzamides; Cell Line; Cisapride; Electrophysiology; Ether-A-Go-Go Potassium Channels; Humans; Imidazoles; Inhibitory Concentration 50; Morpholines; Patch-Clamp Techniques; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists

2007
The in vivo gastrointestinal activity of TD-5108, a selective 5-HT(4) receptor agonist with high intrinsic activity.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 378, Issue:1

    Topics: Administration, Oral; Animals; Azabicyclo Compounds; Benzamides; Cisapride; Colon; Dogs; Dose-Response Relationship, Drug; Esophagus; Female; Gastrointestinal Transit; Guinea Pigs; Indoles; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists

2008
The in vitro pharmacological profile of TD-5108, a selective 5-HT(4) receptor agonist with high intrinsic activity.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 378, Issue:1

    Topics: Animals; Azabicyclo Compounds; Benzamides; Cell Line; Cisapride; Colon; Cyclic AMP; Esophagus; Ether-A-Go-Go Potassium Channels; Guinea Pigs; Humans; Indoles; Kidney; Morpholines; Protein Binding; Rats; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists

2008
Frequency scale symptoms for gastroesophageal reflux disease (Frequency Scale for Symptoms of GERD) predicts need for addition of prokinetics to proton pump inhibitor therapy.
    Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:8 Pt 1

    Topics: Benzamides; Cisapride; Gastroesophageal Reflux; Gastrointestinal Agents; Gastrointestinal Motility; Humans; Morpholines; Proton Pump Inhibitors; Severity of Illness Index

2008
Effects of mosapride citrate, metoclopramide hydrochloride, lidocaine hydrochloride, and cisapride citrate on equine gastric emptying, small intestinal and caecal motility.
    Research in veterinary science, 2009, Volume: 86, Issue:2

    Topics: Animals; Benzamides; Breath Tests; Carbon Isotopes; Cisapride; Female; Gastric Emptying; Gastrointestinal Agents; Horses; Lidocaine; Male; Metoclopramide; Morpholines

2009
Acotiamide hydrochloride (Z-338), a new selective acetylcholinesterase inhibitor, enhances gastric motility without prolonging QT interval in dogs: comparison with cisapride, itopride, and mosapride.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 336, Issue:3

    Topics: Animals; Benzamides; Benzyl Compounds; CHO Cells; Cholinesterase Inhibitors; Cisapride; Cricetinae; Cricetulus; Dogs; Gastrointestinal Motility; Guinea Pigs; Heart Conduction System; Humans; Male; Morpholines; Thiazoles

2011
Effect of mosapride on Kv4.3 potassium channels expressed in CHO cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:10

    Topics: Animals; Benzamides; CHO Cells; Cisapride; Cricetulus; Morpholines; Potassium Channel Blockers; Shal Potassium Channels

2013