cisapride and acetaminophen

cisapride has been researched along with acetaminophen in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.00)18.7374
1990's9 (36.00)18.2507
2000's8 (32.00)29.6817
2010's6 (24.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Moncrieff, J; Sommers, DK; van Wyk, M1
Nimmo, WS; Parnacott, S; Rowbotham, DJ1
Kluger, MT; Owen, H; Plummer, JL1
Harasawa, S; Kaneshige, H; Kasai, S; Machimura, H; Sakai, H; Takeda, H; Tanaka, K1
Ito, Y; Itoh, Z; Iwanaga, Y; Kato, H; Miyashita, N; Mizutani, F; Morikawa, K1
Bamber, PA; Nimmo, WS; Rowbotham, DJ1
Nimmo, WS; Rowbotham, DJ1
Furuhama, K; Hatanaka, S; Kawarabayashi, K; Kondoh, M1
Cook, DJ; Guyatt, GH; Heyland, DK; Tougas, G1
Abraha, TW; Blackford, JT; Doherty, TJ; Frazier, DL; Valk, N1
Jones, AW; Jönsson, KA; Kechagias, S1
Brown, RO; Dickerson, RN; Gervasio, JM; Headley, S; Kudsk, KA; Kuhl, DA; Lima, JJ; Livingston, TN; MacLaren, R; Swift, K1
Mizutani, Y; Suzuki, T; Takeda, M; Tsukamoto, K; Yamano, M1
Itoh, H; Nagano, T; Takeyama, M1
Itoh, Z; Koto, M; Omura, S; Onoma, M; Ozaki, K; Takanashi, H; Yogo, K1
Akima, M; Itoh, Z; Kamei, K; Koga, H; Omura, S; Onoma, M; Ozaki, K; Takanashi, H; Yogo, K1
Her, C1

Trials

9 trial(s) available for cisapride and acetaminophen

ArticleYear
No effect of cisapride on paracetamol absorption after oral simultaneous administration.
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adult; Cisapride; Double-Blind Method; Drug Combinations; Gastric Emptying; Humans; Intestinal Absorption; Male; Piperidines; Serotonin Antagonists

1992
The influence of rectal cisapride on morphine-induced gastric stasis.
    Anaesthesia and intensive care, 1991, Volume: 19, Issue:3

    Topics: Acetaminophen; Administration, Rectal; Adult; Cisapride; Double-Blind Method; Female; Gastric Emptying; Humans; Injections, Intramuscular; Intestinal Absorption; Male; Middle Aged; Morphine; Piperidines; Placebos; Preanesthetic Medication; Rectum; Serotonin Antagonists; Suppositories

1991
Comparison of the effect of cisapride and metoclopramide on morphine-induced delay in gastric emptying.
    British journal of clinical pharmacology, 1988, Volume: 26, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Cisapride; Clinical Trials as Topic; Double-Blind Method; Female; Gastric Emptying; Humans; Intestinal Absorption; Male; Metoclopramide; Middle Aged; Morphine; Piperidines; Premedication; Random Allocation; Time Factors

1988
Effect of cisapride on morphine-induced delay in gastric emptying.
    British journal of anaesthesia, 1987, Volume: 59, Issue:5

    Topics: Acetaminophen; Adolescent; Adult; Cisapride; Gastric Emptying; Humans; Intestinal Absorption; Male; Middle Aged; Morphine; Piperidines; Preanesthetic Medication; Stimulation, Chemical; Time Factors

1987
Cisapride improves gastric emptying in mechanically ventilated, critically ill patients. A randomized, double-blind trial.
    American journal of respiratory and critical care medicine, 1996, Volume: 154, Issue:6 Pt 1

    Topics: Acetaminophen; Anti-Ulcer Agents; Cisapride; Critical Illness; Double-Blind Method; Female; Gastric Emptying; Humans; Male; Middle Aged; Piperidines; Respiration, Artificial; Serotonin Antagonists

1996
Effect of cisapride on gastric emptying in horses following endotoxin treatment.
    Equine veterinary journal, 1998, Volume: 30, Issue:4

    Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Area Under Curve; Cisapride; Endotoxins; Female; Gastric Emptying; Gastrointestinal Agents; Horse Diseases; Horses; Intestinal Obstruction; Piperidines; Postoperative Complications

1998
Impact of gastric emptying on the pharmacokinetics of ethanol as influenced by cisapride.
    British journal of clinical pharmacology, 1999, Volume: 48, Issue:5

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Area Under Curve; Central Nervous System Depressants; Cisapride; Cross-Over Studies; Drug Interactions; Ethanol; Gastric Emptying; Gastrointestinal Agents; Humans; Male

1999
Sequential single doses of cisapride, erythromycin, and metoclopramide in critically ill patients intolerant to enteral nutrition: a randomized, placebo-controlled, crossover study.
    Critical care medicine, 2000, Volume: 28, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adult; Aged; Antiemetics; Cisapride; Critical Illness; Cross-Over Studies; Enteral Nutrition; Erythromycin; Female; Gastric Emptying; Gastrointestinal Agents; Humans; Intestinal Absorption; Male; Metoclopramide; Middle Aged; Placebos; Respiration, Artificial; Time Factors

2000
Cisapride raises the bioavailability of paracetamol by inhibiting its glucuronidation in man.
    The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:7

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Area Under Curve; Biological Availability; Cisapride; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Agents; Glucuronosyltransferase; Humans; Male; Statistics, Nonparametric

2001

Other Studies

16 other study(ies) available for cisapride and acetaminophen

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Influence of cisapride, metoclopramide and loperamide on gastric emptying of normal volunteers as measured by means of the area under the curve of the cumulative fraction absorbed-time profiles of paracetamol.
    Methods and findings in experimental and clinical pharmacology, 1992, Volume: 14, Issue:5

    Topics: Acetaminophen; Adult; Biological Availability; Cisapride; Gastric Emptying; Humans; Loperamide; Male; Metoclopramide; Piperidines; Serotonin Antagonists

1992
Effect of cisapride on gastric emptying in diabetic patients without gastrointestinal symptoms.
    The Tokai journal of experimental and clinical medicine, 1991, Volume: 16, Issue:2

    Topics: Acetaminophen; Blood Glucose; Cisapride; Diabetes Mellitus, Type 2; Female; Gastric Emptying; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Piperidines; Serotonin Antagonists

1991
Stimulatory effect of N-[4-[2-(dimethylamino)-ethoxy] benzyl]-3,4-dimethoxybenzamide hydrochloride (HSR-803) on normal and delayed gastrointestinal propulsion.
    Japanese journal of pharmacology, 1991, Volume: 56, Issue:3

    Topics: Acetaminophen; Administration, Oral; Animals; Benzamides; Benzyl Compounds; Cisapride; Dogs; Domperidone; Dopamine; Dyspepsia; Female; Gastric Emptying; Gastrointestinal Motility; Male; Metoclopramide; Mice; Piperidines; Rats; Rats, Inbred Strains; Stimulation, Chemical

1991
The measurement of gastric emptying in conscious rats by monitoring serial changes in serum acetaminophen level.
    Journal of pharmacological and toxicological methods, 1994, Volume: 31, Issue:3

    Topics: Acetaminophen; Administration, Oral; Animals; Cisapride; Gastric Emptying; Male; Phenolsulfonphthalein; Piperidines; Rats; Rats, Sprague-Dawley; Sincalide; Time Factors

1994
Gastric emptying in diabetic gastroparetic dogs: ffects of SK-951,a novel prokinetic agent.
    Pharmacology, 2001, Volume: 62, Issue:1

    Topics: Acetaminophen; Animals; Benzofurans; Blood Glucose; Body Weight; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Diabetes Mellitus, Experimental; Dogs; Gastric Emptying; Gastrointestinal Agents; Gastroparesis; Male; Time Factors

2001
Effects of oral mitemcinal (GM-611), erythromycin, EM-574 and cisapride on gastric emptying in conscious rhesus monkeys.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:4

    Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Cisapride; Consciousness; Erythromycin; Gastric Emptying; Gastrointestinal Agents; Macaca mulatta; Male

2008
Oral mitemcinal (GM-611), an erythromycin-derived prokinetic, accelerates normal and experimentally delayed gastric emptying in conscious dogs.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:1

    Topics: Acetaminophen; Administration, Oral; Animals; Cisapride; Clonidine; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Duodenum; Erythromycin; Gastric Emptying; Gastric Mucosa; Gastrointestinal Agents; Gastrointestinal Motility; Gastroparesis; Postprandial Period; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Stomach; Time Factors; Vagotomy

2008
Acetaminophen-induced, not desflurane-induced, hepatotoxicity.
    Anesthesiology, 2008, Volume: 109, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Anti-Ulcer Agents; Chemical and Drug Induced Liver Injury; Cisapride; Cytochrome P-450 Enzyme System; Desflurane; Diagnosis, Differential; Humans; Infant; Isoflurane; Liver; Male; Mobius Syndrome; Omeprazole; Ophthalmologic Surgical Procedures

2008