ciproxifan and imidazole

ciproxifan has been researched along with imidazole* in 1 studies

Other Studies

1 other study(ies) available for ciproxifan and imidazole

Article	Year
Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates. Bioorganic & medicinal chemistry letters, 2009, Dec-01, Volume: 19, Issue:23 A series of imidazole-containing (non-)chiral carbamates were tested at human histamine H(3) receptor (H(3)R). All compounds displayed K(i) values below 100 nM. A trend for a stereoselectivity at human H(3)R was observed for the chiral alpha-branched ligands. Selected compounds were also tested at human histamine H(4) receptor and showed moderate to weak affinities (118-1460 nM). Topics: Carbamates; Drug Design; Humans; Imidazoles; Molecular Structure; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship	2009

Article

Year

Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates.

Bioorganic & medicinal chemistry letters, 2009, Dec-01, Volume: 19, Issue:23

A series of imidazole-containing (non-)chiral carbamates were tested at human histamine H(3) receptor (H(3)R). All compounds displayed K(i) values below 100 nM. A trend for a stereoselectivity at human H(3)R was observed for the chiral alpha-branched ligands. Selected compounds were also tested at human histamine H(4) receptor and showed moderate to weak affinities (118-1460 nM).

Topics: Carbamates; Drug Design; Humans; Imidazoles; Molecular Structure; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship

2009