ciprofloxacin and theophylline

ciprofloxacin has been researched along with theophylline in 82 studies

Research

Studies (82)

Timeframe	Studies, this research(%)	All Research%
pre-1990	23 (28.05)	18.7374
1990's	39 (47.56)	18.2507
2000's	9 (10.98)	29.6817
2010's	11 (13.41)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cortijo, J; Gálvez, J; García-Domenech, R; Morcillo, E; Ríos-Santamarina, I; Santamaria, P	1
Caron, G; Ermondi, G	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chyrek-Borowska, S; Michalska, I; Siergiejko, Z; Szymański, W	1
Carnegie, CM; Lindsay, G; Scorer, HJ	1
Gordon, T; Hamilton, RA	1
Bader, MB	1
Davis, RL; Kelly, HW; Powell, JR; Quenzer, RW	1
LeBel, M; Parent, M	1
FitzGerald, MX; O'Mahony, MS	1
Goodwin, SD; Heyd, A; Nix, DE; Wilton, JH	1
Allen, N; Semel, JD	1
Goss, TF; Laughlin, PH; Nix, DE; Spivey, JM	1
Michaud, R; Sesin, GP	1
Flowers, MK; Taylor, DM	1
LeBel, M; Parent, M; St-Laurent, M	1
Christ, W	1
Bachmann, KA; Sullivan, TJ	1
Richardson, JP	1
Atkinson, HC; Begg, EJ; Frampton, CM; Robson, RA; Saunders, DA	1
Harris, JM	1
Guzelian, PS; Hunt, C; Karnes, HT; Polk, RE; Sarkar, M	1
Erickson, S; Paidipaty, B	1
Bentley, DW; Karki, SD; Raghavan, M	1
Pedersen, SS	1
Polk, RE	1
Healy, DP; Kanawati, L; Mooney, ML; Polk, RE; Rock, DT	1
Adair, CG; Casabar, E; Kasik, JE; Lettieri, J; Prince, RA; Wexler, DB	1
Eckert, G; Kropp, R	1
Beer, C; Harder, S; Papenburg, A; Shah, PM; Staib, AH; Stille, W	1
Rehavi, M; Rubinstein, E; Segev, S	1
Baur, C; Davies, BI; Maesen, FP	1
Bem, JL; Mann, RD	1
Holden, R	1
Bachmann, KA; Jauregui, L; Schwartz, JI	1
Bachmann, K; Jauregui, L; Lettieri, J; Schwartz, J	1
Duraski, RM	1
Hepburn, M; Thomson, AH; Thomson, GD; Whiting, B	1
Beer, C; Frech, K; Harder, S; Mieke, S; Shah, PM; Staib, AH; Stille, W	1
Kawane, H; Niki, Y; Soejima, R; Sumi, M; Umeki, S	1
Baars, AM; van Herwaarden, CL; Vree, TB; Wijnands, WJ	2
Rubinstein, E; Segev, S	1
Afzal, Q; Guarneri, JJ; Khan, FA; LaBombardi, V; Raoof, S; Wollschlager, CM	1
DeVito, JM; Nix, DE; Schentag, JJ; Whitbread, MA	1
Khan, FA; Raoof, S; Wollschlager, C	1
Bowles, SK; Chandrasekar, PH; Edwards, DJ; Rybak, MJ	1
Korrapati, MR; Muppalla, S; Vestal, RE; Wei, X; Zhai, S	1
Batty, KT; Davis, TM; Dusci, LJ; Ilett, KF; Langton, SR	1
Aarons, L; Davis, JD; Houston, JB	2
Echevarria, KH	1
Nightingale, CH; Zhi, J	1
Embardo, LS; Rockwood, RP	1
Climo, MW; Gillum, JG; Israel, DS; Polk, RE; Scott, RB	1
Guanci, R; Lilley, LL	1
Kunze, KL; Parker, BM; Vestal, RE; Wei, X; Zhai, S	1
Haefeli, WE; Ritz, R; Schlienger, RG; Wyser, C	1
de'Clari, F	1
Cusack, BJ; Loi, CM; Parker, BM; Vestal, RE	1
Cusack, BJ; Loi, CM; Parker, BM; Vestal, R	1
Breisch, S; Chodosh, S; Lakshminarayan, S; Swarz, H	1
Pons, G; Rey, E; Tréluyer, JM	1
Hajime, N; Kamberi, M; Kamberi, P; Nakamura, K; Nakano, S; Uemura, N	1
Amighi, K; Hamdani, J; Moës, AJ	1
Aly, ZH; Radwan, MA; Zaghloul, IY	1
Gagne, JJ; Maio, V; Rabinowitz, C	1
Antoniou, T; Gomes, T; Juurlink, DN; Mamdani, MM	1
Bellini, MS; Clavel, A; Lodi, A; Pijnenburg, N	1
Lightstone, FC; Navid, A; Ng, DM; Wong, SE	1

Reviews

7 review(s) available for ciprofloxacin and theophylline

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Meta-analysis of quinolone-theophylline interactions. DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:2 Topics: Ciprofloxacin; Drug Interactions; Enoxacin; Humans; Meta-Analysis as Topic; Quinolones; Theophylline	1991
Clinical efficacy of ciprofloxacin in lower respiratory tract infections. Scandinavian journal of infectious diseases. Supplementum, 1989, Volume: 60 Topics: Ciprofloxacin; Clinical Trials as Topic; Cystic Fibrosis; Drug Interactions; Humans; Lung Diseases, Obstructive; Meta-Analysis as Topic; Pneumonia, Mycoplasma; Respiratory Tract Infections; Theophylline	1989
Drug-drug interactions with ciprofloxacin and other fluoroquinolones. The American journal of medicine, 1989, Nov-30, Volume: 87, Issue:5A Topics: Antacids; Caffeine; Ciprofloxacin; Cyclosporins; Drug Interactions; Humans; Intestinal Absorption; Rifampin; Theophylline	1989
Drug interactions of ciprofloxacin with other non-antibiotic agents. The American journal of medicine, 1987, Apr-27, Volume: 82, Issue:4A Topics: Administration, Oral; Animals; Central Nervous System; Ciprofloxacin; Drug Interactions; Eukaryotic Cells; Humans; Intestinal Absorption; Theophylline	1987
[Clinico-pharmacological case (4). Epileptic seizure as an unwanted drug effect on theophylline poisoning]. Praxis, 1996, Oct-29, Volume: 85, Issue:44 Topics: Aged; Atrial Fibrillation; Ciprofloxacin; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Male; Theophylline	1996
Drug disposition in cystic fibrosis. Clinical pharmacokinetics, 1998, Volume: 35, Issue:4 Topics: Absorption; Anti-Infective Agents; Ciprofloxacin; Cloxacillin; Cyclosporine; Cystic Fibrosis; Fleroxacin; Humans; Theophylline; Tissue Distribution	1998

Trials

14 trial(s) available for ciprofloxacin and theophylline

Article	Year
[Effect of ofloxacin, ciprofloxacin and nalidixic acid on serum theophylline level in patients treated with methylxanthine preparations]. Pneumonologia i alergologia polska, 1992, Volume: 60, Issue:1-2 Topics: Administration, Oral; Adult; Aminophylline; Asthma; Biological Availability; Ciprofloxacin; Drug Therapy, Combination; Humans; Middle Aged; Nalidixic Acid; Ofloxacin; Theophylline; Time Factors	1992
Safety and efficacy of temafloxacin versus ciprofloxacin in lower respiratory tract infections: a randomized, double-blind trial. The Journal of antimicrobial chemotherapy, 1992, Volume: 30, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteria; Ciprofloxacin; Double-Blind Method; Drug Interactions; Female; Fluoroquinolones; Humans; Male; Middle Aged; Prospective Studies; Quinolones; Respiratory Tract Infections; Theophylline	1992
Effect of the addition of ciprofloxacin on theophylline pharmacokinetics in subjects inhibited by cimetidine. The Annals of pharmacotherapy, 1992, Volume: 26, Issue:1 Topics: Adult; Cimetidine; Ciprofloxacin; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Drug Therapy, Combination; Female; Half-Life; Humans; Infusions, Intravenous; Liver; Male; Metabolic Clearance Rate; Theophylline	1992
Comparative effects of ciprofloxacin and lomefloxacin on the oxidative metabolism of theophylline. British journal of clinical pharmacology, 1990, Volume: 29, Issue:4 Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Fluoroquinolones; Humans; Male; Oxidation-Reduction; Quinolones; Random Allocation; Theophylline	1990
Clinical efficacy of ciprofloxacin in lower respiratory tract infections. Scandinavian journal of infectious diseases. Supplementum, 1989, Volume: 60 Topics: Ciprofloxacin; Clinical Trials as Topic; Cystic Fibrosis; Drug Interactions; Humans; Lung Diseases, Obstructive; Meta-Analysis as Topic; Pneumonia, Mycoplasma; Respiratory Tract Infections; Theophylline	1989
Effect of quinolone antimicrobials on theophylline pharmacokinetics. Journal of clinical pharmacology, 1989, Volume: 29, Issue:7 Topics: Adult; Ciprofloxacin; Half-Life; Humans; Male; Metabolic Clearance Rate; Nalidixic Acid; Norfloxacin; Random Allocation; Theophylline	1989
4-quinolones inhibit biotransformation of caffeine. European journal of clinical pharmacology, 1988, Volume: 35, Issue:6 Topics: Adult; Biotransformation; Caffeine; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Interactions; Enoxacin; Humans; Male; Molecular Structure; Norfloxacin; Ofloxacin; Pipemidic Acid; Quinolones; Random Allocation; Theophylline	1988
[Gyrase inhibitors can delay caffeine elimination]. Deutsche medizinische Wochenschrift (1946), 1986, Sep-26, Volume: 111, Issue:39 Topics: Caffeine; Ciprofloxacin; Enoxacin; Humans; Naphthyridines; Theophylline	1986
Controlled, comparative study of ciprofloxacin versus ampicillin in treatment of bacterial respiratory tract infections. The American journal of medicine, 1987, Apr-27, Volume: 82, Issue:4A Topics: Adult; Aged; Aged, 80 and over; Ampicillin; Bacterial Infections; Ciprofloxacin; Clinical Trials as Topic; Digestive System; Double-Blind Method; Female; Humans; Male; Middle Aged; Penicillin Resistance; Prospective Studies; Respiratory Tract Infections; Theophylline	1987
Effect of multiple dose oral ciprofloxacin on the pharmacokinetics of theophylline and indocyanine green. The Journal of antimicrobial chemotherapy, 1987, Volume: 19, Issue:2 Topics: Administration, Oral; Ciprofloxacin; Drug Interactions; Half-Life; Humans; Indocyanine Green; Kinetics; Male; Random Allocation; Regression Analysis; Theophylline	1987
Effect of combination therapy with ciprofloxacin and clarithromycin on theophylline pharmacokinetics in healthy volunteers. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:7 Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Clarithromycin; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Humans; Male; Theophylline	1996
Relation between plasma and saliva concentrations of enoxacin, ciprofloxacin, and theophylline. Therapeutic drug monitoring, 1996, Volume: 18, Issue:6 Topics: Adult; Anti-Infective Agents; Bronchodilator Agents; Ciprofloxacin; Drug Interactions; Enoxacin; Female; Humans; Male; Protein Binding; Saliva; Theophylline	1996
Individual and combined effects of cimetidine and ciprofloxacin on theophylline metabolism in male nonsmokers. British journal of clinical pharmacology, 1993, Volume: 36, Issue:3 Topics: Adult; Bronchodilator Agents; Cimetidine; Ciprofloxacin; Drug Interactions; Humans; Male; Smoking; Theophylline	1993
Efficacy and safety of a 10-day course of 400 or 600 milligrams of grepafloxacin once daily for treatment of acute bacterial exacerbations of chronic bronchitis: comparison with a 10-day course of 500 milligrams of ciprofloxacin twice daily. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:1 Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Bronchodilator Agents; Chronic Disease; Ciprofloxacin; Double-Blind Method; Drug Administration Schedule; Female; Fluoroquinolones; Humans; Male; Middle Aged; Piperazines; Prospective Studies; Quinolones; Theophylline; Treatment Outcome	1998

Other Studies

62 other study(ies) available for ciprofloxacin and theophylline

Article	Year
New bronchodilators selected by molecular topology. Bioorganic & medicinal chemistry letters, 1998, Mar-03, Volume: 8, Issue:5 Topics: Animals; Bronchodilator Agents; Discriminant Analysis; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Structure-Activity Relationship; Trachea	1998
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Incidence and cost of hospital admissions secondary to drug interactions involving theophylline. The Annals of pharmacotherapy, 1992, Volume: 26, Issue:12 Topics: Aged; Aged, 80 and over; Cimetidine; Ciprofloxacin; Drug Interactions; Erythromycin; Health Care Costs; Hospitalization; Hospitals, Veterans; Humans; Male; New York; Patient Admission; Theophylline	1992
Role of ciprofloxacin in fatal seizures. Chest, 1992, Volume: 101, Issue:3 Topics: Ciprofloxacin; Drug Interactions; Humans; Male; Middle Aged; Status Epilepticus; Theophylline	1992
Cystic fibrosis and seizures. Lancet (London, England), 1991, Jul-27, Volume: 338, Issue:8761 Topics: Adult; Ciprofloxacin; Cystic Fibrosis; Humans; Seizures; Theophylline	1991
Compatibility of ciprofloxacin injection with selected drugs and solutions. American journal of hospital pharmacy, 1991, Volume: 48, Issue:10 Topics: Amikacin; Anti-Bacterial Agents; Ciprofloxacin; Clindamycin; Drug Compounding; Drug Incompatibility; Drug Stability; Drug Storage; Drug Therapy, Combination; Gentamicins; Metronidazole; Solutions; Theophylline; Tobramycin	1991
Seizures in patients simultaneously receiving theophylline and imipenem or ciprofloxacin or metronidazole. Southern medical journal, 1991, Volume: 84, Issue:4 Topics: Aged; Ciprofloxacin; Drug Interactions; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Imipenem; Male; Metronidazole; Middle Aged; Monitoring, Physiologic; Seizures; Theophylline	1991
Theophylline toxicity secondary to ciprofloxacin administration. Annals of emergency medicine, 1991, Volume: 20, Issue:10 Topics: Aged; Charcoal; Ciprofloxacin; Drug Interactions; Female; Humans; Theophylline	1991
Computer monitoring ciprofloxacin-theophylline interactions. DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:9 Topics: Ciprofloxacin; Computers; Drug Interactions; Humans; Theophylline	1991
Variable theophylline clearance in cystic fibrosis. DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:2 Topics: Adult; Ciprofloxacin; Cystic Fibrosis; Drug Interactions; Humans; Male; Metabolic Clearance Rate; Theophylline	1991
Safety of fleroxacin coadministered with theophylline to young and elderly volunteers. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:6 Topics: Adult; Aged; Aging; Anti-Infective Agents; Ciprofloxacin; Drug Therapy, Combination; Fleroxacin; Humans; Male; Theophylline	1990
Central nervous system toxicity of quinolones: human and animal findings. The Journal of antimicrobial chemotherapy, 1990, Volume: 26 Suppl B Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System; Ciprofloxacin; Dogs; Drug Interactions; Fleroxacin; Fluoroquinolones; gamma-Aminobutyric Acid; Humans; Injections, Intraventricular; Narcotic Antagonists; Pefloxacin; Quinolizines; Seizures; Theophylline	1990
Method for assessing the probability of toxicity from drug interactions having a pharmacokinetic basis. Clinical pharmacy, 1990, Volume: 9, Issue:2 Topics: Anti-Bacterial Agents; Cimetidine; Ciprofloxacin; Drug Interactions; Humans; Lactams; Models, Biological; Pharmacokinetics; Probability; Theophylline	1990
Theophylline toxicity associated with the administration of ciprofloxacin in a nursing home patient. Journal of the American Geriatrics Society, 1990, Volume: 38, Issue:3 Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Ciprofloxacin; Drug Interactions; Humans; Male; Nursing Homes; Theophylline; Urinary Tract Infections	1990
Drug interactions affecting theophylline clearance. The Journal of pediatrics, 1990, Volume: 116, Issue:5 Topics: Adolescent; Adult; Ciprofloxacin; Drug Interactions; Enoxacin; Humans; Propranolol; Theophylline	1990
In vitro effect of fluoroquinolones on theophylline metabolism in human liver microsomes. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:4 Topics: Biotransformation; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Interactions; Enoxacin; Humans; Hydroxylation; Microsomes, Liver; Norfloxacin; Theophylline; Uric Acid; Xanthines	1990
Ciprofloxacin-theophylline drug interaction. Critical care medicine, 1990, Volume: 18, Issue:6 Topics: Aged; Aged, 80 and over; Ciprofloxacin; Drug Interactions; Female; Humans; Male; Theophylline	1990
Seizure with ciprofloxacin and theophylline combined therapy. DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:6 Topics: Aged; Aged, 80 and over; Ciprofloxacin; Drug Therapy, Combination; Female; Humans; Male; Seizures; Theophylline	1990
Interaction between oral ciprofloxacin and caffeine in normal volunteers. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:4 Topics: Adult; Caffeine; Ciprofloxacin; Drug Interactions; Half-Life; Humans; Male; Theophylline	1989
[Interaction of gyrase inhibitor with theophylline]. Praxis und Klinik der Pneumologie, 1987, Volume: 41, Issue:12 Topics: Aged; Ciprofloxacin; Delayed-Action Preparations; Drug Interactions; Humans; Middle Aged; Theophylline; Topoisomerase II Inhibitors	1987
Quinolones, theophylline, and diclofenac interactions with the gamma-aminobutyric acid receptor. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:11 Topics: Animals; Ciprofloxacin; Diclofenac; Drug Synergism; GABA Antagonists; In Vitro Techniques; Male; Muscimol; Nalidixic Acid; Ofloxacin; Quinolones; Rats; Rats, Inbred Strains; Receptors, GABA-A; Theophylline	1988
Ciprofloxacin in the treatment of acute exacerbations of chronic bronchitis. European journal of clinical microbiology, 1986, Volume: 5, Issue:2 Topics: Aged; Anti-Bacterial Agents; Bacterial Infections; Bronchitis; Chronic Disease; Ciprofloxacin; Drug Therapy, Combination; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Male; Middle Aged; Neisseriaceae; Pneumococcal Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolines; Sputum; Streptococcus pneumoniae; Theophylline	1986
Danger of interaction between ciprofloxacin and theophylline. British medical journal (Clinical research ed.), 1988, Apr-16, Volume: 296, Issue:6629 Topics: Adolescent; Adult; Aged; Ciprofloxacin; Drug Interactions; Female; Humans; Male; Middle Aged; Theophylline	1988
Probable fatal interaction between ciprofloxacin and theophylline. BMJ (Clinical research ed.), 1988, Nov-19, Volume: 297, Issue:6659 Topics: Aged; Ciprofloxacin; Drug Interactions; Female; Heart Rate; Humans; Liver; Theophylline	1988
Predicting the ciprofloxacin-theophylline interaction from single plasma theophylline measurements. British journal of clinical pharmacology, 1988, Volume: 26, Issue:2 Topics: Administration, Oral; Adult; Ciprofloxacin; Drug Interactions; Humans; Male; Theophylline	1988
Impact of ciprofloxacin on theophylline clearance and steady-state concentrations in serum. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:1 Topics: Adult; Ciprofloxacin; Delayed-Action Preparations; Drug Interactions; Humans; Male; Theophylline	1988
Ciprofloxacin-induced theophylline toxicity. Southern medical journal, 1988, Volume: 81, Issue:9 Topics: Aged; Aged, 80 and over; Ciprofloxacin; Drug Interactions; Female; Humans; Tachycardia, Supraventricular; Theophylline	1988
A clinically significant interaction between ciprofloxacin and theophylline. European journal of clinical pharmacology, 1987, Volume: 33, Issue:4 Topics: Aged; Aged, 80 and over; Ciprofloxacin; Drug Interactions; Humans; Male; Theophylline	1987
New synthetic quinolone antibacterial agents and serum concentration of theophylline. Chest, 1987, Volume: 92, Issue:4 Topics: Adult; Anti-Infective Agents; Chemical Phenomena; Chemistry; Ciprofloxacin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Male; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid; Theophylline	1987
Steady-state kinetics of the quinolone derivatives ofloxacin, enoxacin, ciprofloxacin and pefloxacin during maintenance treatment with theophylline. Drugs, 1987, Volume: 34 Suppl 1 Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Enoxacin; Female; Humans; Male; Middle Aged; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Theophylline	1987
The influence of the 4-quinolones ciprofloxacin, pefloxacin and ofloxacin on the elimination of theophylline. Pharmaceutisch weekblad. Scientific edition, 1987, Dec-11, Volume: 9 Suppl Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Lung Diseases, Obstructive; Male; Metabolic Clearance Rate; Middle Aged; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Theophylline	1987
Ciprofloxacin increases serum levels of theophylline. The American journal of medicine, 1987, Apr-27, Volume: 82, Issue:4A Topics: Administration, Oral; Adult; Aged; Ciprofloxacin; Drug Interactions; Female; Humans; Injections, Intravenous; Male; Middle Aged; Theophylline	1987
Increased theophylline concentrations secondary to ciprofloxacin. Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:11 Topics: Aged; Aged, 80 and over; Ciprofloxacin; Drug Interactions; Humans; Male; Theophylline	1987
Simultaneous determination of theophylline, enoxacin and ciprofloxacin in human plasma and saliva by high-performance liquid chromatography. Journal of chromatography. B, Biomedical applications, 1995, Jul-21, Volume: 669, Issue:2 Topics: Anti-Infective Agents; Bronchodilator Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Humans; Male; Reproducibility of Results; Saliva; Theophylline	1995
The effect of ciprofloxacin on theophylline pharmacokinetics in healthy subjects. British journal of clinical pharmacology, 1995, Volume: 39, Issue:3 Topics: Administration, Oral; Adolescent; Adult; Chromatography, High Pressure Liquid; Ciprofloxacin; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Fluorescence Polarization; Humans; Male; Metabolic Clearance Rate; Mixed Function Oxygenases; Oxidoreductases; Theophylline	1995
Relationship between enoxacin and ciprofloxacin plasma concentrations and theophylline disposition. Pharmaceutical research, 1994, Volume: 11, Issue:10 Topics: Animals; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Infusions, Intravenous; Male; Rats; Rats, Sprague-Dawley; Theophylline	1994
A warning on the use of Cipro. The Nurse practitioner, 1994, Volume: 19, Issue:6 Topics: Aged; Ciprofloxacin; Drug Interactions; Humans; Lung Diseases, Obstructive; Theophylline	1994
Biphenylacetate, but not theophylline, lethally interacts with ciprofloxacin in mice. Pharmacology & toxicology, 1993, Volume: 73, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Drug Interactions; Female; Mice; Phenylacetates; Seizures; Theophylline	1993
Simultaneous assay of fluoroquinolones and theophylline in plasma by high-performance liquid chromatography. Journal of chromatography, 1993, Nov-17, Volume: 621, Issue:1 Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Male; Norfloxacin; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Theophylline	1993
Theophylline, ciprofloxacin, erythromycin: a potentially harmful regimen. The Annals of pharmacotherapy, 1993, Volume: 27, Issue:5 Topics: Aged; Aged, 80 and over; Ciprofloxacin; Drug Interactions; Erythromycin; Humans; Theophylline	1993
Avoiding adverse reactions. The American journal of nursing, 1996, Volume: 96, Issue:9 Topics: Antacids; Anti-Infective Agents; Asthma; Bronchodilator Agents; Ciprofloxacin; Drug Interactions; Humans; Male; Middle Aged; Pneumonia; Theophylline	1996
Ciprofloxacin was the culprit--not itraconazole. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Bronchodilator Agents; Central Nervous System; Ciprofloxacin; Clarithromycin; Drug Interactions; Drug Therapy, Combination; Humans; Itraconazole; Theophylline; Time Factors	1997
Aging and drug interactions. III. Individual and combined effects of cimetidine and cimetidine and ciprofloxacin on theophylline metabolism in healthy male and female nonsmokers. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2 Topics: Adult; Age Factors; Aged; Aging; Analysis of Variance; Biotransformation; Cimetidine; Ciprofloxacin; Creatinine; Drug Interactions; Female; Humans; Male; Metabolic Clearance Rate; Regression Analysis; Sex Characteristics; Theophylline	1997
Simultaneous determination of grepafloxacin, ciprofloxacin, and theophylline in human plasma and urine by HPLC. Therapeutic drug monitoring, 1999, Volume: 21, Issue:3 Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Interactions; Drug Monitoring; Fluoroquinolones; Humans; Piperazines; Reproducibility of Results; Sensitivity and Specificity; Theophylline	1999
Development and in vitro evaluation of a novel floating multiple unit dosage form obtained by melt pelletization. International journal of pharmaceutics, 2006, Sep-28, Volume: 322, Issue:1-2 Topics: Ciprofloxacin; Delayed-Action Preparations; Diglycerides; Drug Compounding; Excipients; Fatty Acids; Sodium Bicarbonate; Tetracycline; Theophylline	2006
The effect of chronic cadmium exposure on the pharmacokinetics of theophylline and ciprofloxacin in rats. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2007, Volume: 21, Issue:2 Topics: Animals; Anti-Infective Agents; Bronchodilator Agents; Cadmium Chloride; Ciprofloxacin; Female; Humans; Male; Rats; Rats, Sprague-Dawley; Theophylline	2007
Prevalence and predictors of potential drug-drug interactions in Regione Emilia-Romagna, Italy. Journal of clinical pharmacy and therapeutics, 2008, Volume: 33, Issue:2 Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Aminophylline; Anti-Inflammatory Agents, Non-Steroidal; Barbiturates; Child; Child, Preschool; Ciprofloxacin; Drug Interactions; Drug Utilization; Female; Fluvoxamine; Humans; Italy; Male; Middle Aged; Outpatients; Theophylline; Warfarin	2008
Ciprofloxacin-induced theophylline toxicity: a population-based study. European journal of clinical pharmacology, 2011, Volume: 67, Issue:5 Topics: Aged; Aged, 80 and over; Case-Control Studies; Ciprofloxacin; Drug Interactions; Female; Humans; Male; Ontario; Pulmonary Disease, Chronic Obstructive; Theophylline	2011
Determination of water content by capillary gas chromatography coupled with thermal conductivity detection. Pharmeuropa bio & scientific notes, 2011, Volume: 2011, Issue:2 Topics: Amoxicillin; Anti-Bacterial Agents; Chromatography, Gas; Ciprofloxacin; European Union; Indicators and Reagents; Pharmaceutical Preparations; Solvents; Spectinomycin; Theophylline; Thermal Conductivity; Water	2011
Application of a Physiologically Based Pharmacokinetic Model to Study Theophylline Metabolism and Its Interactions With Ciprofloxacin and Caffeine. CPT: pharmacometrics & systems pharmacology, 2016, Volume: 5, Issue:2 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Bronchodilator Agents; Caffeine; Ciprofloxacin; Computer Simulation; Dose-Response Relationship, Drug; Drug Dosage Calculations; Drug Interactions; Female; Humans; Male; Middle Aged; Models, Biological; Precision Medicine; Sex Factors; Theophylline	2016