ciprofloxacin and pyrazinamide

ciprofloxacin has been researched along with pyrazinamide in 67 studies

Research

Studies (67)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.49)	18.7374
1990's	13 (19.40)	18.2507
2000's	7 (10.45)	29.6817
2010's	37 (55.22)	24.3611
2020's	9 (13.43)	2.80

Authors

Authors	Studies
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S	1
Imramovský, A; Jampílek, J; Kaustová, J; Kocevar, M; Polanc, S; Recková, Z; Vinsová, J	1
Connell, TG; Curtis, N; Ritz, N; Robins-Browne, R; Sievers, A; Tebruegge, M	1
Gaillard, JL; Jackson, M; McDonnell, G; Niederweis, M; Skovierová, H; Svetlíková, Z	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Banerjee, D; Kumar, RS; Perumal, S; Rajesh, SM; Sriram, D; Yogeeswari, P	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Perumal, S; Raja, VP; Sriram, D; Yogeeswari, P	1
Bosze, S; Horváti, K; Kočevar, M; Polanc, S; Stolaříková, J; Vavříková, E; Vávrová, K; Vinšová, J	1
Murugavel, M; Muthusubramanian, S; Paul, N; Sriram, D	1
Chikhalia, KH; Kumari, P; Patel, PK; Patel, RV; Rajani, DP	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Doležal, M; Kubíček, V; Kučera, R; Kuneš, J; Mandíková, J; Paterová, P; Servusová, B; Zitko, J	1
Bharate, SS; Vishwakarma, RA	1
Askri, M; Boudriga, S; Golz, C; Knorr, M; Mhiri, C; Nana, F; Sriram, D; Strohmann, C; Yogeeswari, P	1
Anand, A; Dixit, SR; Joshi, SD; Kulkarni, MV; Naik, RJ; Revankar, HM	1
Dalimba, U; Nayak, N; Ramprasad, J	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Abouelhassan, Y; Bai, F; Burch, GM; Garrison, AT; Huigens, RW; Jin, S; Kallifidas, D; Luesch, H; Nguyen, MT; Norwood, VM; Rolfe, M	1
Chakraborti, AK; Dhameliya, TM; Jadhavar, PS; Pancholia, S; Shah, P; Sridevi, JP; Sriram, D; Yogeshwari, P	1
Chakraborti, AK; Dhameliya, TM; Jadhavar, PS; Kumar, D; Sridevi, JP; Sriram, D; Vaja, MD; Yogeeswari, P	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Anand, A; Dixit, SR; Joshi, SD; Kulkarni, MV	1
Chakraborti, AK; Kumar, A; Sriram, D; Tanwar, B; Yogeeswari, P	1
Balaji, NV; Hari Babu, B; Murali Krishna Kumar, M; Purna Nagasree, K; Subbaraju, GV	1
Alegaon, SG; Salve, PS; Sriram, D	1
Desai, S; Desai, V; Dixit, SK; Gaonkar, SN; Joshi, SD; Palyekar, U	1
Fan, YL; Feng, LS; Gao, T; Huang, ZP; Jin, XH; Yu, HF; Zeng, ZG	1
Banerjee, A; Chakraborti, AK; Dhameliya, TM; Pancholia, S; Panda, D; Sriram, D; Tiwari, R	1
Ashok, D; Goud, GL; Manga, V; Ramesh, S; Reddy, VP; Saikrishna, B; Sriram, D; Yogeeswari, P	1
Bai, L; Deng, J; Feng, L; Lv, Z; Wang, Y; Xu, Z; Zhang, F; Zhao, S	1
Dalimba, U; Madan Kumar, S; Reddyrajula, R	1
Bera, S; Mondal, D	1
Anil Kumar, GN; Joshi, SD; Khanapurmath, N; Kulkarni, MV	1
Dalimba, U; Reddyrajula, R	1
Augustynowicz-Kopeć, E; Bojanowski, K; Foks, H; Gobis, K; Głogowska, A; Korona-Głowniak, I; Krause, M; Siluk, D; Ziembicka, D	1
Krishna Kumar Muthyala, M; Kurati, S; Tirumalasetty, M; Veeravarapu, H; Wunnava, U	1
Cordeiro, R; Kachroo, M	1
Trotsko, N	1
Bayannavar, PK; Hoolageri, SR; Joshi, SD; Kamble, RR; Kodasi, B; Kumbar, VM; Nesaragi, AR; Shaikh, SKJ	1
Ahmad, I; Alshahrani, MY; Jain, R; Pradeep Kumar, CB; Prashanth, MK; Raghu, MS; Yogesh Kumar, K	1
Agrahari, AK; Rajkhowa, S; Sharma, A; Tiwari, VK	1
Collins, CH; Uttley, AH	1
Nelson, SD; Nolan, CM; Sandblom, RE; Slattery, JT; Thummel, KE	1
Daniel, TM; Stevens, JP	2
Gallagher, CT; Passannante, MR; Reichman, LB	1
Gillespie, SH; Kennedy, N	1
Greten, T; Hautmann, H; Huber, RM; Trauner, A	1
Ahn, CH; Brown, BA; Dunbar, D; Dunlap, R; Murphy, DT; Onyi, G; Wallace, RJ	1
Fox, R; Gillespie, SH; Kennedy, N; Kisyombe, GM; Ngowi, FI; Ramsay, AR; Saruni, AO; Uiso, LO	1
Berger, L; Curram, J; Fox, R; Gillespie, SH; Gutmann, J; Kennedy, N; Kisyombe, GM; Ngowi, FI; Ramsay, AR; Sam, N; Saruni, AO; Tillotson, G; Uiso, LO; Yates, M	1
Nolan, CM	1
Coker, RJ; Fisher, M; Tomlinson, DR	1
Drobniewski, FA; Eltringham, IJ; Wilson, SM	1
Bartsch, P; Corhay, JL; Gach, O; Lousberg, L	1
Cox, VC; Elwood, RK; FitzGerald, JM; Marra, F; Moadebi, S	1
Carbonell, D; Fernández-Olivera, N; García-García, I; López-Saura, PA; Machado-Molina, D; Milanés-Virelles, MT; Suárez-Méndez, R; Valdés-Quintana, M; Valenzuela-Silva, CM	1
Campbell, PJ; Cowan, LS; Dalton, TL; Hooks, DP; Metchock, B; Morlock, GP; Plikaytis, BB; Posey, JE; Sikes, RD; Starks, AM	1
Ambrose, PG; Bhavnani, SM; Caws, M; Chau, TT; Dung, NT; Farrar, J; Hammel, JP; Hien, TT; Kulawy, R; Mai, PP; Reynolds, DK; Thwaites, GE; Török, ME; Van Wart, SA	1
Patsche, CB; Svensson, E; Wejse, C	1
Eakambaram, RS; Ibrahim, IA; Krishnasamy, SK; Mathew, S; Namasivayam, V; Natarajan, A; Palaniappan, S	1
Jung, JA; Kaisar, N; Parvez, MM; Shin, HJ; Shin, JG	1
Clifton, DA; Crook, DW; Iqbal, Z; Niehaus, KE; Peto, TEA; Smith, EG; Walker, AS; Walker, TM; Wilson, DJ; Yang, Y; Zhu, T	1
Alsayed, SSR; Bishai, WR; Gunosewoyo, H; Lun, S; Payne, A	1

Reviews

8 review(s) available for ciprofloxacin and pyrazinamide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Recent advances of imidazole-containing derivatives as anti-tubercular agents. European journal of medicinal chemistry, 2018, Apr-25, Volume: 150 Topics: Animals; Antitubercular Agents; Dose-Response Relationship, Drug; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis	2018
Benzofuran derivatives and their anti-tubercular, anti-bacterial activities. European journal of medicinal chemistry, 2019, Jan-15, Volume: 162 Topics: Anti-Bacterial Agents; Antitubercular Agents; Benzofurans; Humans; Structure-Activity Relationship	2019
Insights of synthetic analogues of anti-leprosy agents. Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13 Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship	2019
Antitubercular properties of thiazolidin-4-ones - A review. European journal of medicinal chemistry, 2021, Apr-05, Volume: 215 Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Structure-Activity Relationship; Thiazolidines; THP-1 Cells; Vero Cells	2021
Emerging impact of triazoles as anti-tubercular agent. European journal of medicinal chemistry, 2022, Aug-05, Volume: 238 Topics: Antitubercular Agents; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles; Tuberculosis	2022
[Esophagomediastinal fistulae as a rare complication of tuberculosis in an HIV-infected patient]. Deutsche medizinische Wochenschrift (1946), 1994, Nov-25, Volume: 119, Issue:47 Topics: AIDS-Related Opportunistic Infections; Ciprofloxacin; Drug Therapy, Combination; Esophageal Fistula; Ethambutol; Fistula; HIV-1; Humans; Male; Mediastinal Diseases; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node	1994
Multidrug-resistant tuberculosis in the USA: the end of the beginning. Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1996, Volume: 77, Issue:4 Topics: Antitubercular Agents; BCG Vaccine; Ciprofloxacin; Health Personnel; Humans; Pyrazinamide; Tuberculosis, Multidrug-Resistant; United States	1996

Trials

4 trial(s) available for ciprofloxacin and pyrazinamide

Article	Year
Early bactericidal and sterilizing activities of ciprofloxacin in pulmonary tuberculosis. The American review of respiratory disease, 1993, Volume: 148, Issue:6 Pt 1 Topics: Adult; Aged; Ciprofloxacin; Drug Therapy, Combination; Ethambutol; Female; HIV Seropositivity; HIV-1; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary	1993
Randomized controlled trial of a drug regimen that includes ciprofloxacin for the treatment of pulmonary tuberculosis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:5 Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Ethambutol; Female; HIV-1; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Pulmonary	1996
Adjuvant interferon gamma in patients with drug - resistant pulmonary tuberculosis: a pilot study. BMC infectious diseases, 2004, Oct-22, Volume: 4 Topics: Adjuvants, Immunologic; Adult; Amikacin; Antitubercular Agents; Ciprofloxacin; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; Follow-Up Studies; Humans; Interferon-gamma; Kanamycin; Male; Middle Aged; Mycobacterium tuberculosis; Pilot Projects; Pyrazinamide; Radiography; Recombinant Proteins; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary	2004
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:7 Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Injections, Intramuscular; Isoniazid; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal; Young Adult	2011

Other Studies

55 other study(ies) available for ciprofloxacin and pyrazinamide

Article	Year
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen	2007
A new modification of anti-tubercular active molecules. Bioorganic & medicinal chemistry, 2007, Apr-01, Volume: 15, Issue:7 Topics: Antitubercular Agents; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Half-Life; Isoniazid; Kinetics; Lipids; Microbial Sensitivity Tests; Mycobacterium avium; Mycobacterium kansasii; Pyrazinamide; Quantitative Structure-Activity Relationship	2007
Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1 Topics: Antitubercular Agents; BCG Vaccine; Microbial Sensitivity Tests; Mycobacterium bovis	2009
Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9 Topics: Antitubercular Agents; Disinfectants; Drug Resistance, Bacterial; Glutaral; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Mycobacterium chelonae; Mycobacterium smegmatis; o-Phthalaldehyde; Porins	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Novel three-component domino reactions of ketones, isatin and amino acids: synthesis and discovery of antimycobacterial activity of highly functionalised novel dispiropyrrolidines. European journal of medicinal chemistry, 2010, Volume: 45, Issue:1 Topics: Amino Acids; Anti-Bacterial Agents; Isatin; Ketones; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Mycobacterium tuberculosis; Pyrrolidines	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Synthesis and antimycobacterial activity of highly functionalized tetrahydro-4(1H)-pyridinones. Bioorganic & medicinal chemistry letters, 2011, Jul-01, Volume: 21, Issue:13 Topics: Anti-Bacterial Agents; Crystallography, X-Ray; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium tuberculosis; Pyridones	2011
New fluorine-containing hydrazones active against MDR-tuberculosis. European journal of medicinal chemistry, 2011, Volume: 46, Issue:10 Topics: Animals; Antitubercular Agents; Cell Line; Fluorine; Humans; Hydrazones; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium kansasii; Plasma; Rats; Tuberculosis, Multidrug-Resistant	2011
Camphorsulfonic acid catalysed facile tandem double Friedlander annulation protocol for the synthesis of phenoxy linked bisquinoline derivatives and discovery of antitubercular agents. Bioorganic & medicinal chemistry letters, 2012, Feb-15, Volume: 22, Issue:4 Topics: Animals; Antitubercular Agents; Camphor; Catalysis; Chemistry Techniques, Synthetic; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Phenols; Quinolines; Structure-Activity Relationship	2012
Synthesis of benzimidazolyl-1,3,4-oxadiazol-2ylthio-N-phenyl (benzothiazolyl) acetamides as antibacterial, antifungal and antituberculosis agents. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Antifungal Agents; Antitubercular Agents; Bacteria; Benzothiazoles; Chemistry Techniques, Synthetic; Fungi; Microbial Sensitivity Tests; Mycobacterium tuberculosis	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Alkylamino derivatives of pyrazinamide: synthesis and antimycobacterial evaluation. Bioorganic & medicinal chemistry letters, 2014, Jan-15, Volume: 24, Issue:2 Topics: Anti-Bacterial Agents; Antifungal Agents; Antitubercular Agents; Crystallography; Drug Evaluation, Preclinical; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide	2014
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery. Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7 Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics	2015
Design of novel dispirooxindolopyrrolidine and dispirooxindolopyrrolothiazole derivatives as potential antitubercular agents. Bioorganic & medicinal chemistry letters, 2015, Oct-01, Volume: 25, Issue:19 Topics: Animals; Antitubercular Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrrolidines; Spiro Compounds; Structure-Activity Relationship; Thiazoles	2015
A click chemistry approach for the synthesis of mono and bis aryloxy linked coumarinyl triazoles as anti-tubercular agents. European journal of medicinal chemistry, 2015, Nov-13, Volume: 105 Topics: Antitubercular Agents; Click Chemistry; Coumarins; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Quantitative Structure-Activity Relationship; Triazoles	2015
New INH-pyrazole analogs: Design, synthesis and evaluation of antitubercular and antibacterial activity. Bioorganic & medicinal chemistry letters, 2015, Dec-01, Volume: 25, Issue:23 Topics: Anti-Bacterial Agents; Antitubercular Agents; Bacteria; Binding Sites; Drug Design; Inhibitory Concentration 50; Isoniazid; Microbial Sensitivity Tests; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Pyrazoles	2015
Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis. Journal of medicinal chemistry, 2016, 04-28, Volume: 59, Issue:8 Topics: Biofilms; Carbon-13 Magnetic Resonance Spectroscopy; Drug Resistance, Bacterial; Drug Screening Assays, Antitumor; Halogens; HeLa Cells; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phenazines; Proton Magnetic Resonance Spectroscopy; Structure-Activity Relationship	2016
Benzo[d]thiazol-2-yl(piperazin-1-yl)methanones as new anti-mycobacterial chemotypes: Design, synthesis, biological evaluation and 3D-QSAR studies. European journal of medicinal chemistry, 2016, Jun-30, Volume: 116 Topics: Animals; Antitubercular Agents; Chemistry Techniques, Synthetic; Drug Design; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Mycobacterium tuberculosis; Piperazine; Piperazines; Quantitative Structure-Activity Relationship; RAW 264.7 Cells	2016
Synthesis, biological evaluation and structure-activity relationship of 2-styrylquinazolones as anti-tubercular agents. Bioorganic & medicinal chemistry letters, 2016, 06-01, Volume: 26, Issue:11 Topics: Antitubercular Agents; Cell Survival; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Quinazolines; Structure-Activity Relationship	2016
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
One pot Click chemistry: A three component reaction for the synthesis of 2-mercaptobenzimidazole linked coumarinyl triazoles as anti-tubercular agents. Bioorganic & medicinal chemistry letters, 2016, 10-01, Volume: 26, Issue:19 Topics: Antitubercular Agents; Benzimidazoles; Click Chemistry; Molecular Docking Simulation; Triazoles	2016
Design, development of new synthetic methodology, and biological evaluation of substituted quinolines as new anti-tubercular leads. Bioorganic & medicinal chemistry letters, 2016, 12-15, Volume: 26, Issue:24 Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Quinolines; Structure-Activity Relationship; Tuberculosis	2016
Synthesis, screening and docking analysis of hispolon analogs as potential antitubercular agents. Bioorganic & medicinal chemistry letters, 2017, 01-01, Volume: 27, Issue:1 Topics: Antitubercular Agents; Catechols; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship	2017
Three-component, one-pot synthesis of anthranilamide Schiff bases bearing 4-aminoquinoline moiety as Mycobacterium tuberculosis gyrase inhibitors. Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8 Topics: Aminoquinolines; Animals; Antitubercular Agents; DNA Gyrase; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; ortho-Aminobenzoates; Schiff Bases; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tuberculosis; Vero Cells	2017
Novel quinoxalinyl chalcone hybrid scaffolds as enoyl ACP reductase inhibitors: Synthesis, molecular docking and biological evaluation. Bioorganic & medicinal chemistry letters, 2017, 05-15, Volume: 27, Issue:10 Topics: Anti-Infective Agents; Antineoplastic Agents; Binding Sites; Candida albicans; Cell Proliferation; Chalcones; Disk Diffusion Antimicrobial Tests; Drug Design; Enoyl-CoA Hydratase; Enzyme Inhibitors; Escherichia coli; Humans; MCF-7 Cells; Molecular Docking Simulation; Mycobacterium tuberculosis; Protein Structure, Tertiary; Staphylococcus aureus	2017
Benzo[d]thiazole-2-carbanilides as new anti-TB chemotypes: Design, synthesis, biological evaluation, and structure-activity relationship. European journal of medicinal chemistry, 2018, Jul-15, Volume: 155 Topics: Animals; Antitubercular Agents; Carbanilides; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; RAW 264.7 Cells; Structure-Activity Relationship; Thiazoles	2018
Design, synthesis, molecular-docking and antimycobacterial evaluation of some novel 1,2,3-triazolyl xanthenones. MedChemComm, 2017, Mar-01, Volume: 8, Issue:3 Topics:	2017
Molecular hybridization approach for phenothiazine incorporated 1,2,3-triazole hybrids as promising antimicrobial agents: Design, synthesis, molecular docking and in silico ADME studies. European journal of medicinal chemistry, 2019, Apr-15, Volume: 168 Topics: Adsorption; Animals; Anti-Bacterial Agents; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Design; Escherichia coli; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Phenothiazines; Pseudomonas aeruginosa; Staphylococcus aureus; Structure-Activity Relationship; Triazoles; Vero Cells	2019
A click chemistry approach for the synthesis of cyclic ureido tethered coumarinyl and 1-aza coumarinyl 1,2,3-triazoles as inhibitors of Mycobacterium tuberculosis H37Rv and their in silico studies. Bioorganic & medicinal chemistry, 2019, 10-15, Volume: 27, Issue:20 Topics: Algorithms; Antitubercular Agents; Click Chemistry; Coumarins; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles; Uracil	2019
The bioisosteric modification of pyrazinamide derivatives led to potent antitubercular agents: Synthesis via click approach and molecular docking of pyrazine-1,2,3-triazoles. Bioorganic & medicinal chemistry letters, 2020, 01-15, Volume: 30, Issue:2 Topics: Antitubercular Agents; Humans; Molecular Docking Simulation; Molecular Structure; Pyrazinamide; Structure-Activity Relationship; Triazoles	2020
4-Substituted picolinohydrazonamides as a new class of potential antitubercular agents. European journal of medicinal chemistry, 2020, Mar-15, Volume: 190 Topics: Animals; Antitubercular Agents; Bacteria; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Pyridines; Thiosemicarbazones; Yeasts	2020
Design, synthesis, antimycobacterial activity and molecular docking studies of novel 3- (N-substituted glycinamido) benzoic acid analogues as anti tubercular agents. Bioorganic & medicinal chemistry letters, 2020, 12-01, Volume: 30, Issue:23 Topics: Antitubercular Agents; Benzoates; Catalytic Domain; Drug Design; Enzyme Inhibitors; Glycine; Methyltransferases; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Protein Binding	2020
Synthesis and biological evaluation of anti-tubercular activity of Schiff bases of 2-Amino thiazoles. Bioorganic & medicinal chemistry letters, 2020, 12-15, Volume: 30, Issue:24 Topics: Amination; Antitubercular Agents; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Schiff Bases; Thiazoles; Tuberculosis	2020
Microwave assisted regioselective synthesis of quinoline appended triazoles as potent anti-tubercular and antifungal agents via copper (I) catalyzed cycloaddition. Bioorganic & medicinal chemistry letters, 2021, 06-01, Volume: 41 Topics: Antifungal Agents; Antitubercular Agents; Aspergillus; Candida albicans; Catalysis; Cell Survival; Copper; Cycloaddition Reaction; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Microbial Sensitivity Tests; Microwaves; Molecular Structure; Mycobacterium tuberculosis; Quinolines; Stereoisomerism; Structure-Activity Relationship; Triazoles	2021
Design, synthesis and molecular docking studies of imidazole and benzimidazole linked ethionamide derivatives as inhibitors of InhA and antituberculosis agents. Bioorganic & medicinal chemistry letters, 2022, 03-15, Volume: 60 Topics: Antitubercular Agents; Benzimidazoles; Dose-Response Relationship, Drug; Drug Design; Ethionamide; Humans; Imidazoles; Inhibins; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship	2022
In vitro activity of ciprofloxacin in combination with standard antituberculous drugs against mycobacterium tuberculosis. Tubercle, 1988, Volume: 69, Issue:3 Topics: Antitubercular Agents; Ciprofloxacin; Ethambutol; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin	1988
Hepatotoxicity associated with acetaminophen usage in patients receiving multiple drug therapy for tuberculosis. Chest, 1994, Volume: 105, Issue:2 Topics: Acetaminophen; Adult; Capreomycin; Ciprofloxacin; Drug Combinations; Drug Overdose; Ethambutol; Female; Humans; Isoniazid; Liver; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	1994
Chemoprophylaxis of multidrug-resistant tuberculous infection in HIV-uninfected individuals using ciprofloxacin and pyrazinamide. A decision analysis. Chest, 1995, Volume: 108, Issue:3 Topics: Adult; Ciprofloxacin; Decision Support Techniques; Decision Trees; Health Personnel; HIV Seronegativity; Humans; Occupational Diseases; Probability; Pyrazinamide; Sensitivity and Specificity; Software; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	1995
Preventive therapy for contacts of multidrug-resistant tuberculosis. A Delphi survey. Chest, 1994, Volume: 106, Issue:2 Topics: Adult; Antitubercular Agents; Ciprofloxacin; Delphi Technique; Humans; Middle Aged; Pyrazinamide; Tuberculosis, Multidrug-Resistant	1994
Early bactericidal activity as a method of assessment of drugs for the treatment of tuberculosis. The Journal of antimicrobial chemotherapy, 1994, Volume: 34, Issue:1 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Isoniazid; Microbial Sensitivity Tests; Predictive Value of Tests; Pyrazinamide; Rifabutin; Time Factors; Tuberculosis	1994
Rifampin-resistant Mycobacterium kansasii. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Amikacin; Antitubercular Agents; Ciprofloxacin; Clinical Protocols; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Pyrazinamide; Pyridoxine; Rifampin; Streptomycin; Texas; Treatment Outcome; Tuberculosis	1994
Bacille Calmette Guérin immunization of health care workers exposed to multidrug-resistant tuberculosis: a decision analysis. Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1996, Volume: 77, Issue:4 Topics: Antitubercular Agents; BCG Vaccine; Ciprofloxacin; Decision Support Techniques; Health Personnel; Humans; Probability; Pyrazinamide; Software; Tuberculosis, Multidrug-Resistant; Vaccination	1996
The management of mycobacterial infections in HIV seropositive individuals. Jefferiss Wing Therapeutics and Protocols Group. International journal of STD & AIDS, 1996, Volume: 7, Issue:4 Topics: Adrenal Cortex Hormones; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Clofazimine; Drug Therapy, Combination; Ethambutol; HIV Infections; Humans; Isoniazid; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Nontuberculous Mycobacteria; Practice Guidelines as Topic; Pyrazinamide; Pyridoxine; Radiography; Rifabutin; Rifampin; Tuberculosis, Meningeal; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	1996
Evaluation of a bacteriophage-based assay (phage amplified biologically assay) as a rapid screen for resistance to isoniazid, ethambutol, streptomycin, pyrazinamide, and ciprofloxacin among clinical isolates of Mycobacterium tuberculosis. Journal of clinical microbiology, 1999, Volume: 37, Issue:11 Topics: Antitubercular Agents; Ciprofloxacin; Drug Resistance, Microbial; Ethambutol; Evaluation Studies as Topic; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacteriophages; Mycobacterium tuberculosis; Phenotype; Pyrazinamide; Streptomycin; Tuberculosis	1999
[Breast abscess and pregnancy toxemia revealing multidrug resistant tuberculosis]. Revue des maladies respiratoires, 1999, Volume: 16, Issue:5 Topics: Abscess; Adult; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antitubercular Agents; Breast Diseases; Bronchoscopy; Cesarean Section; Ciprofloxacin; Drug Therapy, Combination; Eclampsia; Ethambutol; Female; Follow-Up Studies; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications, Infectious; Pyrazinamide; Radiography, Thoracic; Time Factors; Tomography, X-Ray Computed; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	1999
Successful treatment of multidrug-resistant tuberculosis following drug-induced hepatic necrosis requiring liver transplant. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2004, Volume: 8, Issue:7 Topics: Adult; Anti-Infective Agents; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Ciprofloxacin; Drug Hypersensitivity; Drug Resistance, Multiple; Female; Humans; Liver; Liver Transplantation; Necrosis; Pyrazinamide; Tuberculosis, Pulmonary	2004
Molecular detection of mutations associated with first- and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:5 Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; Ciprofloxacin; Ethambutol; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin	2011
Disseminated Mycobacterium celatum disease with prolonged pulmonary involvement. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2014, Volume: 26 Topics: Aged; Anti-Bacterial Agents; Azithromycin; Ciprofloxacin; Clarithromycin; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Lung; Lung Diseases; Mycobacterium; Mycobacterium Infections; Pyrazinamide; Radiography	2014
Design, Synthesis, and Characterization of Some Hybridized Pyrazolone Pharmacophore Analogs against Mycobacterium tuberculosis. Archiv der Pharmazie, 2016, Volume: 349, Issue:5 Topics: Antitubercular Agents; Ciprofloxacin; Drug Design; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Phosphotransferases (Alcohol Group Acceptor); Pyrazinamide; Pyrazolones; Schiff Bases; Streptomycin; Structure-Activity Relationship	2016
Inhibitory Interaction Potential of 22 Antituberculosis Drugs on Organic Anion and Cation Transporters of the SLC22A Family. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:11 Topics: 1-Methyl-4-phenylpyridinium; Aminosalicylic Acid; Animals; Antitubercular Agents; Ciprofloxacin; HEK293 Cells; Humans; Inhibitory Concentration 50; Ion Transport; Kinetics; Levofloxacin; Linezolid; Metformin; Octamer Transcription Factor-1; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 2; Pyrazinamide; Rifabutin; Rifampin; Zidovudine	2016
Machine learning for classifying tuberculosis drug-resistance from DNA sequencing data. Bioinformatics (Oxford, England), 2018, 05-15, Volume: 34, Issue:10 Topics: Antitubercular Agents; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Machine Learning; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant	2018
Facile synthesis and antimycobacterial activity of isoniazid, pyrazinamide and ciprofloxacin derivatives. Chemical biology & drug design, 2021, Volume: 97, Issue:6 Topics: Animals; Antitubercular Agents; Binding Sites; Catalytic Domain; Cell Survival; Chlorocebus aethiops; Ciprofloxacin; DNA Gyrase; Drug Design; Drug Resistance, Bacterial; Isoniazid; Microbial Sensitivity Tests; Molecular Conformation; Molecular Docking Simulation; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Pyrazinamide; Structure-Activity Relationship; Vero Cells	2021