ciprofloxacin has been researched along with probenecid in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (15.38) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 6 (23.08) | 29.6817 |
| 2010's | 12 (46.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Hori, S; Kaji, M; Kaneko, S; Kusajima, H; Miyahara, T; Ooie, T; Saito, A; Saito, S; Shiba, K; Shimada, J | 1 |
| Happonen, HP; Ingervo, L; Jeskanen, L; Karkulahti, R; Karppinen, L; Lassus, A; Reitamo, S | 1 |
| Handsfield, HH; Hook, EW; Roddy, RE | 1 |
| Dell, D; Lücker, PW; Partos, C; Portmann, R; Suter, K; Weidekamm, E | 1 |
| McMillan, A; Scott, GR; Young, H | 1 |
| Jaehde, U; Naber, KG; Reiter, A; Schunack, W; Sigl, G; Sörgel, F | 1 |
| Carbon, C; Dautrey, S; Farinotti, R; Huneau, JF; Ramon, J; Rubinstein, E; St Julien, L | 1 |
| Blackwell, AL; Singh, G; Thomas, PD | 1 |
| Ahmad, AH; Malik, JK; Ramesh, S; Rao, GS; Sharma, LD; Tripathi, HC | 2 |
| Michot, JM; Mingeot-Leclercq, MP; Tulkens, PM; Van Bambeke, F | 1 |
| Bulitta, JB; Holzgrabe, U; Jaehde, U; Kinzig, M; Kirkpatrick, CM; Landersdorfer, CB; Naber, KG; Reiter, A; Rodamer, M; Sörgel, F | 1 |
| Enriquez, RP; Lahra, MM | 1 |
| Ball, K; Chenel, M; Denizot, C; Jamier, T; Mallier, A; Parmentier, Y | 1 |
2 review(s) available for ciprofloxacin and probenecid
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
6 trial(s) available for ciprofloxacin and probenecid
| Article | Year |
|---|---|
Ciprofloxacin versus amoxycillin and probenecid in the treatment of uncomplicated gonorrhoea.
Topics: Adolescent; Adult; Amoxicillin; Chlamydia Infections; Chlamydia trachomatis; Ciprofloxacin; Drug Combinations; Female; Follow-Up Studies; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Neisseria gonorrhoeae; Probenecid; Random Allocation | 1989 |
Comparative trial of single-dose ciprofloxacin and ampicillin plus probenecid for treatment of gonococcal urethritis in men.
Topics: Adolescent; Adult; Ampicillin; Chlamydia Infections; Chlamydia trachomatis; Ciprofloxacin; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Probenecid; Urethritis | 1986 |
Single- and multiple-dose pharmacokinetics of fleroxacin, a trifluorinated quinolone, in humans.
Topics: Administration, Oral; Biological Availability; Ciprofloxacin; Drug Interactions; Fleroxacin; Humans; Infusions, Intravenous; Male; Probenecid | 1987 |
Ciprofloxacin versus ampicillin and probenecid in the treatment of uncomplicated gonorrhoea in men.
Topics: Ampicillin; Ciprofloxacin; Gonorrhea; Humans; Infections; Male; Microbial Sensitivity Tests; Pharyngeal Diseases; Probenecid; Random Allocation; Rectal Diseases | 1987 |
Effect of probenecid on the distribution and elimination of ciprofloxacin in humans.
Topics: Adult; Anti-Infective Agents; Body Fluids; Chromatography, High Pressure Liquid; Ciprofloxacin; Cross-Over Studies; Drug Interactions; Female; Half-Life; Humans; Infusions, Intravenous; Kidney; Male; Probenecid; Renal Agents; Tissue Distribution | 1995 |
Competitive inhibition of renal tubular secretion of ciprofloxacin and metabolite by probenecid.
Topics: Adjuvants, Pharmaceutic; Administration, Oral; Analysis of Variance; Anti-Infective Agents; Ciprofloxacin; Cross-Over Studies; Drug Interactions; Female; Humans; Injections, Intravenous; Kidney Function Tests; Kidney Tubules; Male; Metabolic Clearance Rate; Models, Biological; Probenecid; Statistics as Topic | 2010 |
18 other study(ies) available for ciprofloxacin and probenecid
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Renal handling of fleroxacin in rabbits, dogs, and humans.
Topics: Adult; Animals; Blood Proteins; Ciprofloxacin; Creatinine; Dogs; Fleroxacin; Glomerular Filtration Rate; Humans; Kidney; Kinetics; Male; Probenecid; Protein Binding; Rabbits; Species Specificity | 1990 |
The intestinal elimination of ciprofloxacin in the rat.
Topics: Amoxicillin; Analysis of Variance; Animals; Biological Transport; Chromatography, High Pressure Liquid; Ciprofloxacin; Dose-Response Relationship, Drug; Ileum; Jejunum; Male; Nifedipine; Probenecid; Rats; Rats, Sprague-Dawley | 1994 |
An audit of the problems in management of patients with gonorrhoea.
Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Antitrichomonal Agents; Bacteriological Techniques; Ciprofloxacin; Drug Therapy, Combination; Erythromycin; Female; Gonorrhea; Humans; Male; Metronidazole; Oxytetracycline; Penicillins; Probenecid; Renal Agents; Reproducibility of Results | 1997 |
Effects of endotoxin-induced fever and probenecid on disposition of enrofloxacin and its metabolite ciprofloxacin after intravascular administration of enrofloxacin in goats.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Drug Interactions; Endotoxins; Enrofloxacin; Female; Fever; Fluoroquinolones; Goats; Half-Life; Injections, Intravenous; Metabolic Clearance Rate; Probenecid; Quinolones; Uricosuric Agents | 2000 |
Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin in goats given enrofloxacin alone and in combination with probenecid.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Area Under Curve; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Goats; Half-Life; Injections, Intramuscular; Probenecid; Quinolones; Uricosuric Agents | 2002 |
Active efflux of ciprofloxacin from J774 macrophages through an MRP-like transporter.
Topics: Adenosine Triphosphate; Anti-Infective Agents; Azithromycin; Blotting, Western; Carrier Proteins; Cell Line; Cell Survival; Ciprofloxacin; DNA; Drug Resistance; Drug Resistance, Multiple; Glutathione; Humans; Hydrogen-Ion Concentration; Ionophores; Macrophages; Microscopy, Confocal; Microscopy, Phase-Contrast; Monensin; Probenecid; Protons; Renal Agents; Sulfhydryl Compounds | 2004 |
Australian Gonococcal Surveillance Programme, 1 July to 30 September 2015.
Topics: Amoxicillin; Anti-Bacterial Agents; Australia; Azithromycin; Ceftriaxone; Ciprofloxacin; Drug Resistance, Bacterial; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillins; Probenecid; Public Health Surveillance | 2016 |
Prediction of renal transporter-mediated drug-drug interactions for a drug which is an OAT substrate and inhibitor using PBPK modelling.
Topics: Animals; Area Under Curve; Cell Line; Ciprofloxacin; Drug Interactions; Humans; Inhibitory Concentration 50; Kidney; Macaca fascicularis; Male; Models, Biological; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Permeability; Probenecid; Renal Reabsorption; Tenofovir | 2017 |