ciprofloxacin and phenytoin

ciprofloxacin has been researched along with phenytoin in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (33.33)18.2507
2000's7 (23.33)29.6817
2010's13 (43.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Caron, G; Ermondi, G1
Jolivette, LJ; Ward, KW1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Gozalbes, R; Pineda-Lucena, A1
Sen, S; Sinha, N1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dillard, ML; Fink, RM; Parkerson, R1
Arn, SK; D'Souza, MJ; Jacobs, NF; Job, ML; Strom, JG1
Hull, RL1
Pollak, PT; Slayter, KL2
Brouwers, PJ; de Boer, LE; Guchelaar, HJ1
Springuel, P1
McLeod, R; Trinkle, R1
Morán, D; Otero, MJ; Valverde, MP1
Bhargava, VK; Garg, SK; Islam, AF1
Bhadresa, S; Coon, DJ; Lawrence, MS; Magiera, D; Struharik, M; Ward, KW1
Hanken, I; Sander, CA; Schimmer, M1
Gribakina, OG; Kolyvanov, GB; Novitskaia, IaG; Seredenin, SB; Smirnov, VV; Zherdev, VP1
Liew, EK; Malladi, SS; Ng, XT; Tan, RK1
El-Kasapy, A; El-Sherbiny, IM; Khalil, IA; Mostafa, A; Osman, A; Salah, M; Shokry, MM1

Reviews

1 review(s) available for ciprofloxacin and phenytoin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

29 other study(ies) available for ciprofloxacin and phenytoin

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Ciprofloxacin-phenytoin interaction.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:2

    Topics: Aged; Ciprofloxacin; Drug Interactions; Humans; Male; Phenytoin; Seizures

1992
Effect of ciprofloxacin on the pharmacokinetics of multiple-dose phenytoin serum concentrations.
    Therapeutic drug monitoring, 1994, Volume: 16, Issue:4

    Topics: Adult; Ciprofloxacin; Drug Interactions; Female; Humans; Male; Phenytoin

1994
Possible phenytoin-ciprofloxacin interaction.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:10

    Topics: Aged; Aged, 80 and over; Ciprofloxacin; Drug Interactions; Epilepsy, Tonic-Clonic; Female; Humans; Phenytoin

1993
Hazards of doubling phenytoin dose in the face of an unrecognized interaction with ciprofloxacin.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:1

    Topics: Ciprofloxacin; Dose-Response Relationship, Drug; Drug Interactions; Humans; Male; Middle Aged; Phenytoin; Seizures

1997
Ciprofloxacin-phenytoin interaction.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:4

    Topics: Aged; Anti-Infective Agents; Anticonvulsants; Ciprofloxacin; Drug Interactions; Humans; Male; Phenytoin; Pneumonia; Seizures

1997
Comment: ciprofloxacin-phenytoin interaction.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:12

    Topics: Adult; Anti-Infective Agents; Anticonvulsants; Ciprofloxacin; Drug Administration Routes; Drug Interactions; Female; Humans; Infusions, Intravenous; Phenytoin

1997
Risk of seizures from concomitant use of ciprofloxacin and phenytoin in patients with epilepsy.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1998, Jan-13, Volume: 158, Issue:1

    Topics: Anti-Infective Agents; Anticonvulsants; Ciprofloxacin; Drug Interactions; Epilepsy; Humans; Phenytoin; Risk; Seizures

1998
Comment: unexpectedly low phenytoin concentration in a patient receiving ciprofloxacin.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:10

    Topics: Aged; Anti-Infective Agents; Anticonvulsants; Ciprofloxacin; Drug Interactions; Female; Humans; Phenytoin; Seizures

1998
Interaction between phenytoin and ciprofloxacin.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:2

    Topics: Anti-Infective Agents; Anticonvulsants; Ciprofloxacin; Drug Interactions; Female; Humans; Middle Aged; Phenytoin; Status Epilepticus; Urinary Tract Infections

1999
Effect of ciprofloxacin on steady state pharmacokinetics of phenytoin in rabbits.
    Indian journal of experimental biology, 1999, Volume: 37, Issue:1

    Topics: Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Male; Phenytoin; Rabbits

1999
Exploration of the African green monkey as a preclinical pharmacokinetic model: oral pharmacokinetic parameters and drug-drug interactions.
    Xenobiotica; the fate of foreign compounds in biological systems, 2009, Volume: 39, Issue:3

    Topics: Animals; Aza Compounds; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Evaluation, Preclinical; Erythromycin; Fluoroquinolones; Lidocaine; Mass Spectrometry; Models, Animal; Moxifloxacin; Pharmacokinetics; Phenytoin; Prednisolone; Propranolol; Quinolines; Species Specificity

2009
Basic measures and systemic medical treatment of patients with toxic epidermal necrolysis.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2010, Volume: 8, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticonvulsants; Bacterial Infections; Ciprofloxacin; Drug Combinations; Female; Folic Acid; Gout Suppressants; Humans; Hydroxocobalamin; Lidocaine; Male; Middle Aged; Phenytoin; Prednisone; Pyridoxine; Stevens-Johnson Syndrome; Superinfection; Survival Rate; Trimethoprim, Sulfamethoxazole Drug Combination

2010
[In vivo evaluation of the metabolic ratio of CYP2C9 and CYP1A2 drug markers after administration of afobazole in comparison to standard inducers and inhibitors of cytochromes].
    Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:11

    Topics: Animals; Anti-Anxiety Agents; Anti-Bacterial Agents; Anticonvulsants; Antifungal Agents; Benzimidazoles; Ciprofloxacin; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Enzyme Inhibitors; Fluconazole; Male; Morpholines; Phenytoin; Rats; Rifampin

2013
Ciprofloxacin eye drops-induced subtherapeutic serum phenytoin levels resulting in breakthrough seizures.
    Singapore medical journal, 2014, Volume: 55, Issue:7

    Topics: Administration, Oral; Aged, 80 and over; Anti-Bacterial Agents; Ciprofloxacin; Drug Interactions; Epilepsy, Temporal Lobe; Female; Hospitalization; Humans; Ophthalmic Solutions; Phenytoin; Psychotic Disorders; Seizures

2014
Multifunctional prosthetic polyester-based hybrid mesh for repairing of abdominal wall hernias and defects.
    Carbohydrate polymers, 2019, Nov-01, Volume: 223

    Topics: Abdominal Wall; Alginates; Animals; Anti-Bacterial Agents; Chitosan; Ciprofloxacin; Dogs; Drug Delivery Systems; Female; Hernia, Abdominal; Male; Micelles; Phenytoin; Polyesters; Prostheses and Implants; Surgical Mesh; Wound Healing

2019