ciprofloxacin and pd 124816

ciprofloxacin has been researched along with pd 124816 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's5 (71.43)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cohen, MA; Domagala, JM; Mailloux, GB; Roland, GE; Suto, MJ1
Bridges, AJ; Culbertson, TP; Domagala, JM; Gambino, L; Hagen, SE; Karrick, G; Porter, K; Sanchez, JP; Sesnie, JA; Spense, FG1
Domagala, JM; Hagen, SE; Heifetz, CL; Hutt, MP; Mich, TF; Sanchez, JP; Trehan, AK1
Cohen, MA; Domagala, JM; Gogliotti, RD; Gracheck, SJ; Huband, MD; Sanchez, JP; Sesnie, JA; Shapiro, MA1
Domagala, JM; Hagen, SE; Joannides, T; Kiely, JS; Laborde, E; Schroeder, MC; Sesnie, JA; Shapiro, MA; Suto, MJ; Vanderroest, S1
García-March, FJ; Jaén-Oltra, J; Pérez-Giménez, F; Salabert-Salvador, MT; Tomás-Vert, F1
Curry, PT; Fiedler, RD; Garvin, JR; Kropko, ML; Theiss, JC1

Other Studies

7 other study(ies) available for ciprofloxacin and pd 124816

ArticleYear
Fluoroquinolones: relationships between structural variations, mammalian cell cytotoxicity, and antimicrobial activity.
    Journal of medicinal chemistry, 1992, Dec-11, Volume: 35, Issue:25

    Topics: Animals; Anti-Infective Agents; Cricetinae; Cricetulus; Fluoroquinolones; Microbial Sensitivity Tests; Structure-Activity Relationship

1992
Synthesis and biological activity of 5-amino- and 5-hydroxyquinolones, and the overwhelming influence of the remote N1-substituent in determining the structure-activity relationship.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Alkylation; Aminoquinolines; Animals; Anti-Bacterial Agents; Bacterial Infections; Chemical Phenomena; Chemistry; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydroxyquinolines; Mice; Microbial Sensitivity Tests; Molecular Structure; Piperazines; Pyrrolidines; Structure-Activity Relationship; Topoisomerase II Inhibitors

1991
7-substituted 5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3- quinolinecarboxylic acids: synthesis and biological activity of a new class of quinolone antibacterials.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:3

    Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Ciprofloxacin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Quinolines; Structure-Activity Relationship

1988
The synthesis, structure-activity, and structure-side effect relationships of a series of 8-alkoxy- and 5-amino-8-alkoxyquinolone antibacterial agents.
    Journal of medicinal chemistry, 1995, Oct-27, Volume: 38, Issue:22

    Topics: Animals; Anti-Bacterial Agents; Bacteria; CHO Cells; Cricetinae; Dermatitis, Phototoxic; Drug Design; Female; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Quinolones; Structure-Activity Relationship

1995
Quinolone antibacterials containing the new 7-[3-(1-aminoethyl)-1- pyrrolidinyl] side chain: the effects of the 1-aminoethyl moiety and its stereochemical configurations on potency and in vivo efficacy.
    Journal of medicinal chemistry, 1993, Apr-02, Volume: 36, Issue:7

    Topics: 4-Quinolones; Animals; Anti-Infective Agents; Cricetinae; Cricetulus; Female; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Pyrrolidines; Stereoisomerism; Structure-Activity Relationship; Topoisomerase II Inhibitors

1993
Artificial neural network applied to prediction of fluorquinolone antibacterial activity by topological methods.
    Journal of medicinal chemistry, 2000, Mar-23, Volume: 43, Issue:6

    Topics: Algorithms; Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Neural Networks, Computer; Structure-Activity Relationship

2000
In vitro induction of micronuclei and chromosome aberrations by quinolones: possible mechanisms.
    Mutation research, 1996, Jun-10, Volume: 352, Issue:1-2

    Topics: Animals; Anti-Infective Agents; Cell Cycle; Cell Survival; Cells, Cultured; Chromosome Aberrations; Ciprofloxacin; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Fibroblasts; Fluoroquinolones; Kinetochores; Lung; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenicity Tests; Mutagens; Quinolones

1996