Compounds > ciprofloxacin

ciprofloxacin and pd-117596

ciprofloxacin has been researched along with pd-117596 in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	13 (92.86)	18.2507
2000's	1 (7.14)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cohen, MA; Domagala, JM; Mailloux, GB; Roland, GE; Suto, MJ	1
Bouzard, D; Coroneos, E; Ledoussal, B	1
Bridges, AJ; Bucsh, R; Domagala, JM; Gogliotti, RD; Hagen, SE; Heifetz, CL; Joannides, ET; Sanchez, JP; Sesnie, JC; Shapiro, MA	1
Bridges, AJ; Culbertson, TP; Domagala, JM; Gambino, L; Hagen, SE; Karrick, G; Porter, K; Sanchez, JP; Sesnie, JA; Spense, FG	1
Domagala, JM; Hagen, SE; Heifetz, CL; Johnson, J	1
Culbertson, TP; Gambino, L; Sanchez, JP; Sesnie, JA	1
Cohen, MA; Domagala, JM; Gogliotti, RD; Gracheck, SJ; Huband, MD; Sanchez, JP; Sesnie, JA; Shapiro, MA	1
Domagala, JM; Gracheck, SJ; Hagen, SE; Sesnie, JA; Stier, MA; Suto, MJ	1
Domagala, JM; Hagen, SE; Joannides, T; Kiely, JS; Laborde, E; Schroeder, MC; Sesnie, JA; Shapiro, MA; Suto, MJ; Vanderroest, S	1
García-March, FJ; Jaén-Oltra, J; Pérez-Giménez, F; Salabert-Salvador, MT; Tomás-Vert, F	1
Bailey, DL; Epling, GA; Kiely, JS; Robertson, DG; Song, B	1
Hall, MC; Piddock, LJ; Walters, RN	1
Bodey, GP; Ho, DH; LeBlanc, B; Rolston, KV	1
Amyes, SG; Barnes, AC; Hastings, TS; Lewin, CS	1

Other Studies

14 other study(ies) available for ciprofloxacin and pd-117596

Article	Year
Fluoroquinolones: relationships between structural variations, mammalian cell cytotoxicity, and antimicrobial activity. Journal of medicinal chemistry, 1992, Dec-11, Volume: 35, Issue:25 Topics: Animals; Anti-Infective Agents; Cricetinae; Cricetulus; Fluoroquinolones; Microbial Sensitivity Tests; Structure-Activity Relationship	1992
Potent non-6-fluoro-substituted quinolone antibacterials: synthesis and biological activity. Journal of medicinal chemistry, 1992, Volume: 35, Issue:1 Topics: 4-Quinolones; Anti-Infective Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydrocarbons, Fluorinated; Microbial Sensitivity Tests; Structure-Activity Relationship	1992
New 8-(trifluoromethyl)-substituted quinolones. The benefits of the 8-fluoro group with reduced phototoxic risk. Journal of medicinal chemistry, 1992, Jan-24, Volume: 35, Issue:2 Topics: 4-Quinolones; Administration, Oral; Animals; Anti-Infective Agents; Bacterial Infections; Female; Injections, Subcutaneous; Mice; Microbial Sensitivity Tests; Photosensitivity Disorders; Structure-Activity Relationship	1992
Synthesis and biological activity of 5-amino- and 5-hydroxyquinolones, and the overwhelming influence of the remote N1-substituent in determining the structure-activity relationship. Journal of medicinal chemistry, 1991, Volume: 34, Issue:3 Topics: Alkylation; Aminoquinolines; Animals; Anti-Bacterial Agents; Bacterial Infections; Chemical Phenomena; Chemistry; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydroxyquinolines; Mice; Microbial Sensitivity Tests; Molecular Structure; Piperazines; Pyrrolidines; Structure-Activity Relationship; Topoisomerase II Inhibitors	1991
Synthesis and biological activity of 5-alkyl-1,7,8-trisubstituted-6-fluoroquinoline-3-carboxylic acids. Journal of medicinal chemistry, 1991, Volume: 34, Issue:3 Topics: 4-Quinolones; Anti-Infective Agents; Chemical Phenomena; Chemistry; Gram-Negative Bacteria; Gram-Positive Bacteria; Methylation; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship	1991
Quinolone antibacterial agents substituted at the 7-position with spiroamines. Synthesis and structure-activity relationships. Journal of medicinal chemistry, 1990, Volume: 33, Issue:8 Topics: Bacteria; Chemical Phenomena; Chemistry; Gram-Negative Bacteria; Gram-Positive Bacteria; Molecular Structure; Piperazines; Pyrrolidines; Quinolines; Spiro Compounds; Structure-Activity Relationship	1990
The synthesis, structure-activity, and structure-side effect relationships of a series of 8-alkoxy- and 5-amino-8-alkoxyquinolone antibacterial agents. Journal of medicinal chemistry, 1995, Oct-27, Volume: 38, Issue:22 Topics: Animals; Anti-Bacterial Agents; Bacteria; CHO Cells; Cricetinae; Dermatitis, Phototoxic; Drug Design; Female; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Quinolones; Structure-Activity Relationship	1995
Synthesis and antibacterial activity of new quinolones containing a 7-[3-(1-amino-1-methylethyl)-1-pyrrolidinyl] moiety. Gram-positive agents with excellent oral activity and low side-effect potential. Journal of medicinal chemistry, 1994, Mar-18, Volume: 37, Issue:6 Topics: 4-Quinolones; Administration, Oral; Animals; Anti-Infective Agents; Cricetinae; Cricetulus; Female; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Naphthyridines; Pyrrolidines; Stereoisomerism; Structure-Activity Relationship	1994
Quinolone antibacterials containing the new 7-[3-(1-aminoethyl)-1- pyrrolidinyl] side chain: the effects of the 1-aminoethyl moiety and its stereochemical configurations on potency and in vivo efficacy. Journal of medicinal chemistry, 1993, Apr-02, Volume: 36, Issue:7 Topics: 4-Quinolones; Animals; Anti-Infective Agents; Cricetinae; Cricetulus; Female; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Pyrrolidines; Stereoisomerism; Structure-Activity Relationship; Topoisomerase II Inhibitors	1993
Artificial neural network applied to prediction of fluorquinolone antibacterial activity by topological methods. Journal of medicinal chemistry, 2000, Mar-23, Volume: 43, Issue:6 Topics: Algorithms; Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Neural Networks, Computer; Structure-Activity Relationship	2000
Mechanistic studies of the phototoxic potential of PD 117596, a quinolone antibacterial compound. Toxicology and applied pharmacology, 1991, Volume: 111, Issue:2 Topics: 4-Quinolones; Animals; Anti-Infective Agents; Antioxidants; Ciprofloxacin; Dose-Response Relationship, Drug; Fluoroquinolones; Free Radical Scavengers; Hemolysis; Male; Mice; Mice, Inbred Strains; Nalidixic Acid; Nitroso Compounds; Oxygen; Photochemistry; Photolysis; Quinolones; Thiobarbiturates	1991
Phenotypic characterization of quinolone-resistant mutants of Enterobacteriaceae selected from wild type, gyrA type and multiply-resistant (marA) type strains. The Journal of antimicrobial chemotherapy, 1991, Volume: 28, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Enterobacter cloacae; Enterobacteriaceae; Escherichia coli; Fluoroquinolones; Klebsiella pneumoniae; Mutation; Nalidixic Acid; Phenotype; Quinolones; Serratia marcescens; Species Specificity	1991
In-vitro activity of PD 117 596, a new quinolone, against bacterial isolates from cancer patients. The Journal of antimicrobial chemotherapy, 1990, Volume: 26, Issue:1 Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Neoplasms; Quinolones	1990
In vitro activities of 4-quinolones against the fish pathogen Aeromonas salmonicida. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:9 Topics: Aeromonas; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enrofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Osmolar Concentration; Oxolinic Acid; Quinolones; Sodium Chloride	1990