ciprofloxacin and pd 117588

ciprofloxacin has been researched along with pd 117588 in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's6 (60.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cohen, MA; Domagala, JM; Mailloux, GB; Roland, GE; Suto, MJ1
Bridges, AJ; Bucsh, R; Domagala, JM; Gogliotti, RD; Hagen, SE; Heifetz, CL; Joannides, ET; Sanchez, JP; Sesnie, JC; Shapiro, MA1
Bridges, AJ; Culbertson, TP; Domagala, JM; Gambino, L; Hagen, SE; Karrick, G; Porter, K; Sanchez, JP; Sesnie, JA; Spense, FG1
Domagala, JM; Hagen, SE; Heifetz, CL; Johnson, J1
Culbertson, TP; Gambino, L; Sanchez, JP; Sesnie, JA1
Domagala, JM; Heifetz, CL; Hutt, MP; Mich, TF; Nichols, JB; Solomon, M; Worth, DF1
Domagala, JM; Hagen, SE; Heifetz, CL; Hutt, MP; Mich, TF; Sanchez, JP; Trehan, AK1
Domagala, JM; Hagen, SE; Heifetz, CL; Hutt, MP; Nichols, JB; Sanchez, JP; Trehan, AK1
Domagala, JM; Hagen, SE; Joannides, T; Kiely, JS; Laborde, E; Schroeder, MC; Sesnie, JA; Shapiro, MA; Suto, MJ; Vanderroest, S1
García-March, FJ; Jaén-Oltra, J; Pérez-Giménez, F; Salabert-Salvador, MT; Tomás-Vert, F1

Other Studies

10 other study(ies) available for ciprofloxacin and pd 117588

ArticleYear
Fluoroquinolones: relationships between structural variations, mammalian cell cytotoxicity, and antimicrobial activity.
    Journal of medicinal chemistry, 1992, Dec-11, Volume: 35, Issue:25

    Topics: Animals; Anti-Infective Agents; Cricetinae; Cricetulus; Fluoroquinolones; Microbial Sensitivity Tests; Structure-Activity Relationship

1992
New 8-(trifluoromethyl)-substituted quinolones. The benefits of the 8-fluoro group with reduced phototoxic risk.
    Journal of medicinal chemistry, 1992, Jan-24, Volume: 35, Issue:2

    Topics: 4-Quinolones; Administration, Oral; Animals; Anti-Infective Agents; Bacterial Infections; Female; Injections, Subcutaneous; Mice; Microbial Sensitivity Tests; Photosensitivity Disorders; Structure-Activity Relationship

1992
Synthesis and biological activity of 5-amino- and 5-hydroxyquinolones, and the overwhelming influence of the remote N1-substituent in determining the structure-activity relationship.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Alkylation; Aminoquinolines; Animals; Anti-Bacterial Agents; Bacterial Infections; Chemical Phenomena; Chemistry; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydroxyquinolines; Mice; Microbial Sensitivity Tests; Molecular Structure; Piperazines; Pyrrolidines; Structure-Activity Relationship; Topoisomerase II Inhibitors

1991
Synthesis and biological activity of 5-alkyl-1,7,8-trisubstituted-6-fluoroquinoline-3-carboxylic acids.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: 4-Quinolones; Anti-Infective Agents; Chemical Phenomena; Chemistry; Gram-Negative Bacteria; Gram-Positive Bacteria; Methylation; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

1991
Quinolone antibacterial agents substituted at the 7-position with spiroamines. Synthesis and structure-activity relationships.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:8

    Topics: Bacteria; Chemical Phenomena; Chemistry; Gram-Negative Bacteria; Gram-Positive Bacteria; Molecular Structure; Piperazines; Pyrrolidines; Quinolines; Spiro Compounds; Structure-Activity Relationship

1990
1-Substituted 7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8- difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids. New quantitative structure-activity relationships at N1 for the quinolone antibacterials.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Carboxylic Acids; Chemical Phenomena; Chemistry; Mice; Microbial Sensitivity Tests; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors

1988
7-substituted 5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3- quinolinecarboxylic acids: synthesis and biological activity of a new class of quinolone antibacterials.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:3

    Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Ciprofloxacin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Quinolines; Structure-Activity Relationship

1988
Quinolone antibacterial agents. Synthesis and structure-activity relationships of 8-substituted quinoline-3-carboxylic acids and 1,8-naphthyridine-3-carboxylic acids.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Carboxylic Acids; Chemical Phenomena; Chemistry; Gram-Negative Bacteria; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Naphthyridines; Quinolines; Structure-Activity Relationship

1988
Quinolone antibacterials containing the new 7-[3-(1-aminoethyl)-1- pyrrolidinyl] side chain: the effects of the 1-aminoethyl moiety and its stereochemical configurations on potency and in vivo efficacy.
    Journal of medicinal chemistry, 1993, Apr-02, Volume: 36, Issue:7

    Topics: 4-Quinolones; Animals; Anti-Infective Agents; Cricetinae; Cricetulus; Female; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Pyrrolidines; Stereoisomerism; Structure-Activity Relationship; Topoisomerase II Inhibitors

1993
Artificial neural network applied to prediction of fluorquinolone antibacterial activity by topological methods.
    Journal of medicinal chemistry, 2000, Mar-23, Volume: 43, Issue:6

    Topics: Algorithms; Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Neural Networks, Computer; Structure-Activity Relationship

2000