ciprofloxacin and paclitaxel

ciprofloxacin has been researched along with paclitaxel in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.04)18.2507
2000's10 (43.48)29.6817
2010's10 (43.48)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gibbons, S; Kaatz, GW; Zloh, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Dahse, HM; Fu, H; Grabley, S; Han, L; Huang, X; Lin, W; Moellmann, U; Sattler, I1
Hamann, MT; Kasanah, N; Shilabin, AG; Wedge, DE1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Ahmed, SA; Elsohly, MA; Galal, AM; Gul, W; Jacob, MR; Khan, SI; Radwan, MM; Ross, SA; Slade, D; Tekwani, BL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Hamann, MT; Shilabin, AG1
Alla, M; Balasubramanian, S; Bommena, VR; Bommineni, MR; Mandha, SR; Siliveri, S1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Arora, D; Bhushan, S; Gupta, P; Jaglan, S; Kumar, A; Kushwaha, M; Sharma, N; Sharma, V; Singamaneni, V1
Adcock, LL; Carlson, JW; Carson, LF; Carter, JR; Chen, MD; Dunn, D; Fowler, JM; Mitchell, SK; Saltzman, AK; Twiggs, LB1
Conejo, MC; García, I; Pascual, A; Perea, EJ; Salvador, J1
Carlson, JW; Carson, LF; Copeland, LJ; Fowler, JM; Mayer, AR; Mitchell, SK1
Theodoridis, G1
Edginton, A; Höhn, K; Lippert, J; Schmitt, W; Sevestre, M; Solodenko, J; Weiss, W; Willmann, S1
Bahleda, R; Cadranel, J; Ferte, C; Gomez-Roca, C; Loriot, Y; Moldovan, C; Soria, JC; Wislez, M1
Ashar, YV; Chen, ZS; Gao, HL; Gupta, P; Karadkhelkar, NM; Yoganathan, S1

Reviews

2 review(s) available for ciprofloxacin and paclitaxel

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for ciprofloxacin and paclitaxel

ArticleYear
Chemoprophylaxis with ciprofloxacin in ovarian cancer patients receiving paclitaxel: a randomized trial.
    Gynecologic oncology, 1997, Volume: 65, Issue:2

    Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Bacterial Infections; Ciprofloxacin; Female; Humans; Middle Aged; Neutropenia; Ovarian Neoplasms; Paclitaxel

1997

Other Studies

20 other study(ies) available for ciprofloxacin and paclitaxel

ArticleYear
Inhibitors of multidrug resistance (MDR) have affinity for MDR substrates.
    Bioorganic & medicinal chemistry letters, 2004, Feb-23, Volume: 14, Issue:4

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Cell Membrane; Drug Resistance, Microbial; Drug Resistance, Multiple; Ligands; Models, Molecular

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Unusual naphthoquinone derivatives from the twigs of Avicennia marina.
    Journal of natural products, 2007, Volume: 70, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Avicennia; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Humans; Mice; Molecular Structure; Naphthoquinones; Plant Stems; Plants, Medicinal; Structure-Activity Relationship

2007
Lysosome and HER3 (ErbB3) selective anticancer agent kahalalide F: semisynthetic modifications and antifungal lead-exploration studies.
    Journal of medicinal chemistry, 2007, Sep-06, Volume: 50, Issue:18

    Topics: Antifungal Agents; Antineoplastic Agents; Antiparasitic Agents; Cell Line, Tumor; Depsipeptides; Drug Screening Assays, Antitumor; Fusarium; Humans; Lysosomes; Microbiological Techniques; Mycobacterium tuberculosis; Opportunistic Infections; Parasitic Sensitivity Tests; Receptor, ErbB-3; Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Antiprotozoal, anticancer and antimicrobial activities of dihydroartemisinin acetal dimers and monomers.
    Bioorganic & medicinal chemistry, 2009, Dec-01, Volume: 17, Issue:23

    Topics: Acetals; Antifungal Agents; Antineoplastic Agents; Antiprotozoal Agents; Artemisinins; Cell Line, Tumor; Cryptococcus neoformans; Dimerization; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
In vitro and in vivo evaluation of select kahalalide F analogs with antitumor and antifungal activities.
    Bioorganic & medicinal chemistry, 2011, Nov-15, Volume: 19, Issue:22

    Topics: Animals; Antifungal Agents; Antineoplastic Agents; Depsipeptides; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Nude; Microbial Sensitivity Tests; Structure-Activity Relationship

2011
Eco-friendly synthesis and biological evaluation of substituted pyrano[2,3-c]pyrazoles.
    Bioorganic & medicinal chemistry letters, 2012, Aug-15, Volume: 22, Issue:16

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Cell Proliferation; Crystallography, X-Ray; Edema; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; MCF-7 Cells; Microbial Sensitivity Tests; Molecular Conformation; Pyrazoles; Rats

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Valproic acid induces three novel cytotoxic secondary metabolites in Diaporthe sp., an endophytic fungus from Datura inoxia Mill.
    Bioorganic & medicinal chemistry letters, 2018, 07-01, Volume: 28, Issue:12

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Ascomycota; Cell Line, Tumor; Cell Proliferation; Datura; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Escherichia coli; Humans; Microbial Sensitivity Tests; Molecular Conformation; Peptides, Cyclic; Pseudomonas aeruginosa; Staphylococcus aureus; Structure-Activity Relationship; Valproic Acid

2018
Chemoprophylaxis with oral ciprofloxacin in ovarian cancer patients receiving taxol.
    Gynecologic oncology, 1994, Volume: 55, Issue:3 Pt 1

    Topics: Administration, Oral; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Carboplatin; Chi-Square Distribution; Ciprofloxacin; Cisplatin; Costs and Cost Analysis; Female; Fever; Granulocyte Colony-Stimulating Factor; Humans; Ifosfamide; Leukocyte Count; Middle Aged; Neutropenia; Neutrophils; Ovarian Neoplasms; Paclitaxel; Retrospective Studies

1994
Effect of paclitaxel alone or in combination on the intracellular penetration and activity of quinolones in human neutrophils.
    The Journal of antimicrobial chemotherapy, 1996, Volume: 38, Issue:5

    Topics: Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Ciprofloxacin; Cisplatin; Doxorubicin; Fluoroquinolones; Humans; Levofloxacin; Neutrophils; Ofloxacin; Paclitaxel; Quinolones; Staphylococcus aureus

1996
Application of solid-phase microextraction in the investigation of protein binding of pharmaceuticals.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Jan-18, Volume: 830, Issue:2

    Topics: Binding, Competitive; Chromatography, High Pressure Liquid; Ciprofloxacin; Haloperidol; Humans; Kinetics; Naproxen; Nortriptyline; Paclitaxel; Pharmaceutical Preparations; Protein Binding; Quinidine; Quinine; Serum Albumin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Ultrafiltration

2006
Development of a physiology-based whole-body population model for assessing the influence of individual variability on the pharmacokinetics of drugs.
    Journal of pharmacokinetics and pharmacodynamics, 2007, Volume: 34, Issue:3

    Topics: Adult; Age Factors; Algorithms; Body Height; Body Mass Index; Body Weight; Ciprofloxacin; Computer Simulation; Female; Humans; Male; Metabolic Clearance Rate; Models, Biological; Paclitaxel; Pharmacokinetics; Population Surveillance; Racial Groups; Reference Values; Regional Blood Flow; Reproducibility of Results; Sex Factors; User-Computer Interface

2007
Pemetrexed-induced pneumonitis: a case report.
    Clinical lung cancer, 2009, Volume: 10, Issue:5

    Topics: Adrenal Cortex Hormones; Aged; Anti-Infective Agents; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Ciprofloxacin; Cisplatin; Drug Hypersensitivity; Drug Therapy, Combination; Dyspnea; Erythema; Glutamates; Guanine; Humans; Lung; Lung Neoplasms; Male; Neoplasm Recurrence, Local; Paclitaxel; Pemetrexed; Pneumonia; Pulmonary Fibrosis; Recovery of Function; Solitary Pulmonary Nodule

2009
Ciprofloxacin Enhances the Chemosensitivity of Cancer Cells to ABCB1 Substrates.
    International journal of molecular sciences, 2019, Jan-11, Volume: 20, Issue:2

    Topics: ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Molecular Docking Simulation; Neoplasms; Paclitaxel; Protein Binding; Up-Regulation

2019