ciprofloxacin has been researched along with norfloxacin in 817 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 221 (27.05) | 18.7374 |
| 1990's | 185 (22.64) | 18.2507 |
| 2000's | 184 (22.52) | 29.6817 |
| 2010's | 174 (21.30) | 24.3611 |
| 2020's | 53 (6.49) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, P; Cisek, EP; Cornell, CP; Elliott, NC; Gootz, TD; Haskell, SL; Hindahl, MS; Jefson, MR; Mann, DD; McGuirk, PR | 1 |
| Cohen, MA; Domagala, JM; Mailloux, GB; Roland, GE; Suto, MJ | 1 |
| Bridges, AJ; Bucsh, R; Domagala, JM; Gogliotti, RD; Hagen, SE; Heifetz, CL; Joannides, ET; Sanchez, JP; Sesnie, JC; Shapiro, MA | 1 |
| Bridges, AJ; Culbertson, TP; Domagala, JM; Gambino, L; Hagen, SE; Karrick, G; Porter, K; Sanchez, JP; Sesnie, JA; Spense, FG | 1 |
| Koga, H; Ohta, M | 1 |
| Domagala, JM; Hagen, SE; Heifetz, CL; Johnson, J | 1 |
| Inoue, Y; Iuchi, K; Kawahata, Y; Kondo, H; Sotomura, M; Tsukamoto, G; Uno, T | 1 |
| Bouzard, D; Di Cesare, P; Essiz, M; Jacquet, JP; Kessler, RE; Kiechel, JR; Masuyoshi, M; Oki, T; Remuzon, P; Weber, A | 1 |
| Culbertson, TP; Gambino, L; Sanchez, JP; Sesnie, JA | 1 |
| Domagala, JM; Heifetz, CL; Hutt, MP; Mich, TF; Nichols, JB; Solomon, M; Worth, DF | 1 |
| Bouzard, D; Di Cesare, P; Essiz, M; Jacquet, JP; Masuyoshi, M; Oki, T; Remuzon, P; Weber, A | 1 |
| Domagala, JM; Hanna, LD; Heifetz, CL; Hutt, MP; Mich, TF; Sanchez, JP; Solomon, M | 1 |
| Domagala, JM; Heifetz, CL; Mich, TF; Nichols, JB | 1 |
| Chu, DT; Mitscher, LA; Pernet, AG; Sharma, PN; Shen, LL | 1 |
| Borodkin, S; Chu, DT; Fernandes, PB; Lico, IM; Pernet, AG; Rosen, T; Shen, L | 1 |
| Chu, DT; Claiborne, AK; Fernandes, PB; Gracey, EH; Pernet, AG | 1 |
| Chu, DT; Fernandes, PB; Maleczka, RE; Nordeen, CW; Pernet, AG | 1 |
| Carabateas, PM; Daum, SJ; Dorff, PH; Gruett, MD; Pennock, P; Perni, RB; Reuman, M; Saindane, MT; Singh, B; Wentland, MP | 1 |
| Araki, K; Hirayama, F; Ikeda, Y; Iwao, E; Kuroda, T; Moriguchi, A; Uemori, S; Yakushiji, T; Yokoyama, Y | 1 |
| Kawakami, K; Okuno, T; Sakamoto, F; Tsukamoto, G; Uno, T | 1 |
| Dever, JA; Domagala, JM; Gage, JW; Gracheck, SJ; Renau, TE; Sanchez, JP; Shapiro, MA | 1 |
| Cortijo, J; Gálvez, J; García-Domenech, R; Morcillo, E; Ríos-Santamarina, I; Santamaria, P | 1 |
| Baskaran, S; Bharath, KS; Kumar, MS; Lohray, BB; Mallesham, B; Rao, BS; Reddy, BY; Sadhukhan, AK; Sarnaik, HM; Venkateswarlu, S | 1 |
| García-March, FJ; Jaén-Oltra, J; Pérez-Giménez, F; Salabert-Salvador, MT; Tomás-Vert, F | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Atifi, S; Barbe, J; Chevalier, J; Eyraud, A; Mahamoud, A; Pagès, JM | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Cha, R; Diwadkar, VU; Grucz, RG; Kaatz, GW; Kerns, RJ; Rybak, MJ; Vaka, F; Ward, TD | 1 |
| Antón-Fos, GM; Duart, MJ; Mut-Ronda, S; Salabert-Salvador, MT | 1 |
| Bal, TR; Srichakravarthy, N; Sriram, D; Yogeeswari, P | 1 |
| Gibbons, S; Kaatz, GW; Zloh, M | 1 |
| Baroni, M; Cecchetti, V; Cianchetta, G; Cruciani, G; Mannhold, R | 1 |
| Appelbaum, PC; Bhawsar, SB; Bozdogan, B; de Souza, NJ; Desai, VN; Deshpande, PK; Gupte, SV; Hooper, DC; Jacobs, MR; Jha, R; Khorakiwala, HF; Patel, MV; Shetty, N; Shukla, MC; Strahilevitz, J; Yeole, RD | 1 |
| Emami, S; Foroumadi, A; Hassanzadeh, A; Moshafi, MH; Rajaee, M; Shafiee, A; Sokhanvar, K | 1 |
| Brown, NC; Butler, MM; Dix, EJ; Foster, KA; Holm, K; LaMarr, WA; Lamothe, S; Long, ZY; Manikowski, A; Motorina, I; Skow, DJ; Storer, R; Tarantino, PM; Wright, GE; Zhi, C | 1 |
| Bradbury, BJ; Cheng, J; Deshpande, M; Hashimoto, A; Incarvito, CD; Pucci, MJ; Thanassi, JA; Wiles, JA | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bachand, B; Barnes, MH; Bethell, R; Brown, NC; Butler, MM; Cadilhac, C; Charron, S; Comstock, J; Dix, EJ; Foster, KA; Holm, KA; LaMarr, WA; Lamothe, S; Long, ZY; Manikowski, A; Motorina, I; Storer, R; Tarantino, PM; Wright, GE; Xu, WC; Zhi, C | 1 |
| Beikmohammadi, L; Emami, S; Faramarzi, MA; Foroumadi, A; Ghodsi, S; Najjari, S; Samadi, N; Shafiee, A; Shirazi, FH | 1 |
| Bae, T; Chen, PR; Duguid, EM; He, C; Rice, PA; Schneewind, O; Williams, WA | 1 |
| Drlica, K; Hussain, S; Malik, M | 1 |
| Arpin, C; Ba, BB; Caignard, DH; Forfar-Bares, I; Grellet, J; Guillon, J; Jarry, C; Moreau, S; Quentin, C; Vidaillac, C | 1 |
| Catalan, A; de la Campa, AG; Dominguez, L; Escudero, JA; Gonzalez-Zorn, B; Lopez, G; Moreno, MA; Rivero, E; San Millan, A | 1 |
| Dumas, JL; Köhler, T; Reinhardt, A; Ricou, B; Rohner, P; van Delden, C; Wood, P | 1 |
| Caniça, M; Ferreira, E; Leitão, J; Manageiro, V; Mendonça, N | 1 |
| Allison, BD; Goldschmidt, RM; Gomez, L; Grice, CA; Hack, MD; Jones, TK; Morrow, BJ; Motley, ST; Santillán, A; Schwarz, KL; Shaw, KJ; Shinde, S; Tang, L; Venkatesan, H; Wiener, JJ | 1 |
| Cattoir, V; Mazel, D; Nordmann, P; Poirel, L; Soussy, CJ | 1 |
| Courvalin, P; Galimand, M; Périchon, B | 1 |
| Cattoir, V; Nordmann, P; Poirel, L | 2 |
| Arakawa, Y; Kato, H; Kimura, K; Konda, T; Shibata, N; Shibayama, K; Suzuki, S; Wachino, J; Yamane, K | 1 |
| Al-Momani, W; Antunes, NT; Assunção, P; Ayling, RD; Mercier, P; Poveda, JB; Rosales, RS; Tavío, MM | 1 |
| Beceiro, A; Bou, G; Canle, D; Fernández, A; Lasa, I; Latasa, C; Mallo, S; Molina, F; Pérez, A; Pérez, S; Poza, M; Tomás, Mdel M; Villanueva, R | 1 |
| Morgan-Linnell, SK; Zechiedrich, L | 1 |
| Brazas, MD; Breidenstein, EB; Hancock, RE; Overhage, J | 1 |
| Andres, P; Centrón, D; Galas, M; Guerriero, L; Petroni, A; Quiroga, C; Quiroga, MP; Soler Bistué, AJ; Tokumoto, M; Tolmasky, ME; Vargas, LJ; Zorreguieta, A | 1 |
| Jones, GL; Stickler, DJ | 1 |
| Gadaginamath, GS; Joshi, SD; Vagdevi, HM; Vaidya, VP | 1 |
| Chen, T; Khalil, H; Riffon, R; Wang, R; Wang, Z | 1 |
| Arakawa, Y; Suzuki, S; Wachino, J; Yamane, K | 1 |
| Arakawa, Y; Chen, L; Chen, ZL; Deng, YT; Gao, JH; Liu, JH; Zeng, ZL | 1 |
| Alba, V; Alcalde, E; Blasco, MD; Esteve, C; Marti, S; Sánchez-Céspedes, J; Vila, J | 1 |
| Badur, S; Cagatay, AA; Carrër, A; Eraksoy, H; Nordmann, P; Poirel, L | 1 |
| Cattoir, V; Espinal, P; Nordmann, P; Poirel, L; Silva-Sanchez, J | 1 |
| Bammert, GF; Banitt, LS; Barbachyn, MR; Boyle, TP; Bundy, GL; Dolak, LA; Ford, CW; Graber, DR; Hamel, JC; Han, F; Harris, DW; Hromockyj, AE; Hurd, AR; Kamilar, GM; Marotti, KR; Martin, GE; Miller, AA; Mott, JE; Munzner, JB; Palmer, JR; Ruble, JC; Seest, EP; Skepner, JE; Sweeney, MT; Zhong, WZ; Zurenko, GE | 1 |
| Long, F; Rouquette-Loughlin, C; Shafer, WM; Yu, EW | 1 |
| Hiramatsu, K; Kikuchi, K; Ohtsuka, M; Ono, Y; Sasaki, T; Shimizu, K; Takahashi, N | 2 |
| Bailey, AM; Paulsen, IT; Piddock, LJ | 1 |
| Bremont, S; Charavay, F; Courvalin, P; Goarant, C; Le Hello, S; O'Connor, O; Page, S; Vernel-Pauillac, F | 1 |
| Becnel Boyd, L; Morgan-Linnell, SK; Steffen, D; Zechiedrich, L | 1 |
| Becnel Boyd, L; Hamill, RJ; Horton, LB; Jimenez, JR; Maynard, MJ; Morgan-Linnell, SK; Steffen, D; Sucgang, R; Versalovic, J; Zechiedrich, L | 1 |
| Berçot, B; Nordmann, P; Poirel, L | 1 |
| Baptista, BC; Correia, JD; da Fonseca, JD; Martínez-Martínez, L; Pomba, C | 1 |
| Aarestrup, FM; Cavaco, LM; Hasman, H; Xia, S | 1 |
| Wang, X; Zhao, X | 1 |
| Baliani, A; Barrett, MP; Chollet, C; Gilbert, IH; Wong, PE | 1 |
| Choi, SH; Jeong, JY; Jun, JB; Kim, ES; Kim, MN; Kim, YS; Lee, SO; Woo, JH | 1 |
| Bartolomé, R; Coelho, A; González-López, JJ; Larrosa, MN; Lavilla, S; Prats, G | 1 |
| Dionisi, AM; Lucarelli, C; Luzzi, I; Owczarek, S; Villa, L | 1 |
| Chhasatia, MR; Gandhi, DS; Patel, MN | 1 |
| Espinal, P; Gibert, I; Marti, S; Martínez, P; Roca, I; Vila, J | 1 |
| Gaillard, JL; Jackson, M; McDonnell, G; Niederweis, M; Skovierová, H; Svetlíková, Z | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Chandrashekar, SM; Mallikarjuna, BP; Rajendraprasad, Y; Sastry, BS; Sathisha, K; Suresh Kumar, GV | 1 |
| Azéma, J; Dewelle, J; Guidetti, B; Kiss, R; Korolyov, A; Le Calve, B; Malet-Martino, M; Martino, R; Mijatovic, T; Vaysse, J | 1 |
| Caddick, JM; Gunell, M; Hakanen, AJ; Huovinen, P; Jalava, J; Kotilainen, P; Lilly, AJ; Piddock, LJ; Siitonen, A; Webber, MA | 1 |
| Brasme, L; De Champs, C; Duval, V; Forte, D; Guillard, T; Madoux, J; Maiga, A; Maiga, I; Vernet-Garnier, V | 1 |
| Hamasuna, R; Jensen, JS; Osada, Y | 1 |
| Gebreyes, WA; Rajamohan, G; Srinivasan, VB | 1 |
| Larruskain, J; Montes, M; Orden, B; Perez-Trallero, E; Tamayo, E | 1 |
| Brillault, J; Couet, W; De Castro, WV | 1 |
| Courvalin, P; Coyne, S; Guigon, G; Périchon, B | 1 |
| Avdeef, A; Sun, N; Tam, KY; Tsinman, O | 1 |
| Fàbrega, A; Martin, RG; Rosner, JL; Tavio, MM; Vila, J | 1 |
| Bartalesi, F; Bartoloni, A; Gotuzzo, E; Mantella, A; Pallecchi, L; Riccobono, E; Rossolini, GM; Sennati, S; Trigoso, C | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Hakanen, AJ; Huovinen, P; Kotilainen, P; Lehtopolku, M; Nakari, UM; Siitonen, A | 1 |
| Chandrashekar, SM; Kistayya, C; Mallikarjuna, BP; Rajendraprasad, Y; Suresh Kumar, GV | 1 |
| Amsler, KM; Bush, K; Foleno, BD; He, W; Lynch, AS; Macielag, MJ; Morrow, BJ | 1 |
| Blango, MG; Mulvey, MA | 1 |
| Avdeef, A; Tam, KY | 1 |
| Ahn, JH; Bae, IK; Lee, JE; Lee, JJ; Lee, SH; Park, I; Park, KS; Sun, HI; Woo, GJ | 1 |
| Mima, T; Schweizer, HP | 1 |
| Bohnert, JA; Karamian, B; Nikaido, H | 1 |
| Nakaminami, H; Noguchi, N; Sasatsu, M | 1 |
| Chen, S; Chen, Z; Deng, Y; Huang, X; Liu, JH; Liu, Y; Sun, Y; Tian, W; Wu, C; Zeng, Z; Zhao, J | 1 |
| Gadakh, AV; Karale, BK; Pandit, C; Rindhe, SS | 1 |
| Chandrashekar, SM; Mallikarjuna, BP; Rajendra Prasad, Y; Suresh Kumar, GV | 1 |
| Gotoh, N; Hayashi, N; Okuda, J; Wakahara, Y | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Mali, MD; Patel, MM; Patel, SK | 1 |
| Beema Shafreen, RM; Manisankar, P; Nithyanand, P; Pandian, SK; Srinivasan, S | 1 |
| Baylay, AJ; Garvey, MI; Piddock, LJ; Wong, RL | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Briales, A; Díaz de Alba, P; Domínguez-Herrera, J; Pachón, J; Pascual, A; Rodríguez-Martínez, JM; Velasco, C | 1 |
| Chauhan, K; Chauhan, PM; Gupta, L; Mishra, NN; Shukla, PK; Sunduru, N | 1 |
| Bosze, S; Horváti, K; Kočevar, M; Polanc, S; Stolaříková, J; Vavříková, E; Vávrová, K; Vinšová, J | 1 |
| Bowlin, TL; Butler, MM; Ding, X; Nguyen, ST; Peet, NP; Tashjian, TF | 1 |
| Makawana, JA; Mungra, DC; Patel, MP; Patel, RG | 1 |
| Akhaja, TN; Raval, JP | 1 |
| Anderson, KC; Kellogg, GE; Sarkar, A | 1 |
| Barad, HA; Gupta, VK; Kant, R; Pansuriya, BR; Parmar, NJ; Teraiya, SB | 1 |
| Barad, HA; Gupta, VK; Kant, R; Pansuriya, BR; Parmar, NJ | 1 |
| Patel, MP; Patel, RG; Shah, NM | 1 |
| Bonifácio, VD; Gawande, MB; Mhaske, GR; Shelke, SN | 1 |
| Parmar, BD; Parmar, NJ; Patel, RA; Talpada, NP | 1 |
| Kathrotiya, HG; Patel, MP | 1 |
| Kanawade, SB; Rajani, DP; Toche, RB | 1 |
| Jardosh, HH; Patel, MP | 1 |
| Kalinin, AA; Kulik, NV; Mamedov, VA; Voloshina, AD; Zobov, VV | 1 |
| Kumar, A; Srivastava, N | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Alamry, KA; Birs, AS; Gonzalez, CF; Ibrahim, MA; Katritzky, AR; Panda, SS; Serrano, JC | 1 |
| Kalaria, PN; Raval, DK; Satasia, SP | 1 |
| Chen, L; Fan, L; He, ZQ; Jiang, L; Lei, HS; Liu, CP; Liu, J; Peng, XM; Xu, XR; Yang, DC; Zhou, CH; Zhou, FW; Zou, YY | 1 |
| Karad, SC; Purohit, VB; Raval, DK | 1 |
| Bouillon, A; Cresteil, T; Fontaine, F; Héquet, A; Jolivalt, C; Lesnard, A; Rault, S; Voisin-Chiret, AS | 1 |
| Geng, RX; Kumar, KV; Zhang, L; Zhou, CH | 1 |
| Girgis, AS; Hall, CD; Katritzky, AR; Liaqat, S; Panda, SS; Samir, A | 1 |
| Aminabhavi, TM; Dixit, SR; Joshi, SD; Kirankumar, MN; Lherbet, C; Narayan, R; Raju, KV; Yang, KS | 1 |
| Addla, D; Cai, GX; Geng, RX; Li, S; Ponmani, J; Wang, A; Wang, YN; Xie, D; Zhang, L; Zhang, SL; Zhou, CH | 1 |
| Karad, SC; Purohit, VB; Raval, DK; Thakkar, VR; Thakor, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Detistov, OS; Girgis, AS; Katritzky, AR; Mohapatra, PP; Panda, SS; Samir, A | 1 |
| Akylbekov, N; Bulatova, A; Burilov, A; Chugunova, E; Dobrynin, A; Gavrilov, N; Kulik, N; Syakaev, V; Voloshina, A; Zobov, V | 1 |
| Aminabhavi, TM; Dixit, SR; Joshi, SD; Kulkarni, VH; Lherbet, C; Nadagouda, MN | 1 |
| Kamani, RD; Karad, SC; Purohit, VB; Raval, DK; Ray, A; Thakkar, SS; Thakkar, VR; Thakor, P; Thummar, RP; Vaghasiya, BK | 1 |
| Sankar, C; Umamatheswari, S | 1 |
| Doshi, H; Ray, A; Thakkar, SS; Thakor, P | 1 |
| Doshi, H; Ray, A; Thakkar, SS; Thakkar, VR; Thakor, P | 1 |
| Bernardino, AMR; Boechat, N; Dos Santos, MS; Faria, JV; Miguita, AGC; Vegi, PF | 1 |
| Al-Mahmoudy, AMM; Alamry, KA; Asiri, AM; Faidallah, HM; Girgis, AS; Honkanadavar, HH; Ibrahim, TS; Kalmouch, A; Khan, KA; Panda, SS; Samir, A; Thomas, SJ; Tiwari, AD | 1 |
| Cvijetić, IN; Drakulić, BJ; Ernesto de Resende, P; Gibbons, S; Juranić, IO; Stapleton, P; Verbić, TŽ; Zloh, M | 1 |
| Feng, LS; Liu, X; Pan, B; Zhang, GF; Zhang, S | 1 |
| Chu, XM; Gong, KK; Liang, LL; Liu, W; Sun, KL; Wang, C; Zhao, CY | 1 |
| Bai, L; Deng, J; Feng, L; Lv, Z; Wang, Y; Xu, Z; Zhang, F; Zhao, S | 1 |
| Bukhari, SNA; Mallesha, N; Manukumar, HM; Qin, HL; Rakesh, KP; Vivek, HK; Wang, SM; Zha, GF | 1 |
| Bai, L; Deng, JL; Gao, F; Lv, ZS; Wang, Y; Xu, Z; Zhang, F; Zhao, SJ | 1 |
| Guo, H | 1 |
| Gao, F; Wang, T; Xiao, J; Zhang, X | 1 |
| Cai, S; Fang, Z; Guo, Q; Huang, X; Li, Y; Lin, H; Lu, YJ; Sun, N; Tang, Z; Wong, KY; Wong, WL; Yuan, W | 1 |
| Zhang, B | 1 |
| Gao, F; Huang, G; Wang, T; Xiao, J | 1 |
| Ba, Y; Hou, X; Wang, S; Xu, Z; Yang, H; Zhang, J | 1 |
| Chen, T; Li, Z; Lyu, Y; Shan, A; Shang, L; Yang, Y; Zhu, J | 1 |
| Ciura, K; Fallarero, A; Fedorowicz, J; Gilbert-Girard, S; Konopacka, A; Lejnowski, D; Morawska, M; Sączewski, J; Savijoki, K; Skok, Ž; Tomašič, T; Waleron, K | 1 |
| Caljon, G; Cappoen, D; Claes, P; Cools, F; Cos, P; De Kimpe, N; de Macedo, MB; Delputte, P; Holvoet, F; Maes, L; Mangelinckx, S; Matheeussen, A; Meiresonne, T; Neyrolles, O; Piller, T; Semina, E; Torfs, E; Van Calster, K | 1 |
| Gao, F; Huang, G; Xiao, J | 1 |
| Blaskovich, MAT; Pham, TDM; Ziora, ZM | 1 |
| Askar, AA; El-Khalafawy, A; Makhlouf, AH; Ragab, A; Salem, MA | 1 |
| Capito, JE; El-Manawaty, MA; George, RF; Girgis, AS; Panda, SS; Salman, A; Samir, A; Thomas, SJ | 1 |
| Cai, J; Gao, R; Li, C; Li, Q; Sang, P; Wang, M; Zhang, E; Zheng, M | 1 |
| Alves Borges Leal, AL; Araújo de Oliveira Alcântara, F; Barreto, HM; de Siqueira-Júnior, JP; Faillace, MS; Ferreira, JHL; Peláez, WJ; Sampaio Nogueira, CE | 1 |
| Daraji, DG; Jayanthi, S; Patel, HD; Pithawala, EA; Rajani, DP; Rajani, SD | 1 |
| Ansari, MF; Battini, N; Chen, JP; Zhou, CH | 1 |
| Chen, WM; Hou, W; Huang, MY; Lin, J; Meng, Y; Xu, XF; Yu, JH | 1 |
| Amata, E; Barbaraci, C; Dichiara, M; Fallica, AN; Ferroni, C; Gariboldi, MB; Gentile, D; Intagliata, S; Marras, E; Marrazzo, A; Martini, C; Orlandi, VT; Pasquinucci, L; Rescifina, A; Turnaturi, R; Varchi, G | 1 |
| Akhtar, S; Ansari, MM; Ghosh, JK; Mitra, K; Pant, G; Pratap Verma, D; Saroj, J; Singh, BN; Verma, NK | 1 |
| Cai, GX; Gopala, L; Zhang, PL; Zhang, SL; Zhou, CH | 1 |
| Bora, A; Deka, B; Devi, MV; Dihingia, A; Pahari, P; Sarma, S; Sen, T; Singh, AK; Suri, M | 1 |
| Chen, F; Chen, J; Ji, L; Liu, F; Qin, Y; Wang, S; Wang, Y; Wu, P; Xue, J | 1 |
| Fang, B; Fawad Ansari, M; Li, D; Li, FF; Tan, YM; Zhou, CH | 1 |
| Gao, WW; Laiche, MH; Li, YL; Lin, JM; Zhang, PL; Zhou, CH | 1 |
| Yolton, DP | 1 |
| Cobbs, CG; Smith, KR | 1 |
| García, I; Pascual, A; Perea, EJ | 1 |
| Abo-Askar, H; Qadri, SM; Ueno, Y | 1 |
| Almodovar, E; Burns, JJ; Qadri, SM; Rabea, N; Ueno, Y | 1 |
| Arai, S; Gohara, Y; Kawashima, T; Kuwano, K; Matsu-Ura, I | 1 |
| Jones, RN | 2 |
| Kiyota, H; Mitani, H | 1 |
| Erwin, ME; Jones, RN | 1 |
| Aoyama, H; Fukuda, H; Hirai, K; Hosaka, M; Tomizawa, H; Yasue, T | 1 |
| Mitsuhashi, S; Wakebe, H | 1 |
| Hancock, RE; Young, M | 1 |
| Cao, CX; Gao, PX; Neu, HC; Rudin, DE; Silverstein, SC | 1 |
| Drinovec, J | 1 |
| Anderson, RU; Schaeffer, AJ | 1 |
| Brar, GK; Lal, G; Parsad, D; Sing, N; Singh, CP | 1 |
| Kudo, M; Ohkubo, T; Sugawara, K | 1 |
| Fallara, A; Ravaoarinoro, M; Toma, E | 1 |
| Gootz, TD; Martin, BA | 1 |
| Conejo, MC; García, I; Pascual, A; Perea, EJ | 1 |
| Inoue, Y; Ito, K; Kotera, Y; Ohashi, M; Tsukamoto, G | 1 |
| Adler-Mosca, H; Altwegg, M | 1 |
| Cundy, KV; Fasching, CE; Peterson, LR; Willard, KE | 1 |
| Batmanov, VP | 1 |
| Adler-Mosca, H; Altwegg, M; Burnens, A; Lüthy-Hottenstein, J; Martinetti Lucchini, G | 1 |
| Brody, T; Pensak, ML | 1 |
| Avilés, P; Castilla, C; Rodriguez-Tudela, JL; Soriano, F | 1 |
| Grasela, TH; Green, L; Jolson, HM; Tanner, LA | 1 |
| Kaatz, GW; Ruble, CA; Seo, SM | 1 |
| Räisäinen, S; Schildt, R; Syrjälä, H | 1 |
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| Chen, J; Jin, Y; Ren, T; Tang, Y; Wang, S; Wang, X; Zhang, F | 1 |
| Ebrahimzadeh, F; Gholami, S; Jafari-Sales, A; Rostami, A; Zadeh, FA | 1 |
| Gębalski, J; Gospodarek-Komkowska, E; Kwiecińska-Piróg, J; Przekwas, J; Rutkowska, D; Skowron, K; Wałecka-Zacharska, E; Wiktorczyk-Kapischke, N | 1 |
| Du, H; Li, J; Li, Z; Yang, Y; Zhong, Z | 1 |
| Ahmadi, F; Garg, AX; Kim, RB; Knoll, GA; Muanda, FT; Silverman, MS; Sontrop, JM; Sood, MM; Weir, MA; Yoo, E | 1 |
| Gao, Y; Ji, Y; Lin, Y; Lin, Z; Lu, Y; Yang, Y; Zhang, L | 1 |
| Chen, H; Di, X; Ding, J; Lin, J; Sun, W; Zhang, H | 1 |
| Bandeira, PN; Coutinho, HDM; de Andrade, EM; de Freitas, TS; de Lacerda, BCGV; Dos Santos, HS; Marinho, ES; Marinho, MM; Nogueira, CES; Pereira Junior, FN; Pereira, RLS; Rocha, JE; Rodrigues, LG; Teixeira, AMR; Xavier, JC | 1 |
| Do, KH; Lee, WK; Seo, K | 1 |
| Gui, D; Hua, P; Krebs, P; Wu, S; Ying, G; Zhang, J | 1 |
| Bykov, K; Fischer, MA; Gagne, JJ; Kattinakere-Sreedhara, S; Wang, J | 1 |
| Abbasi, A; Afzal, MZ; Hameed, S; Mohiuddin, M | 1 |
| Emara, Y; Fantke, P; Finkbeiner, M; Heß, S; Jolliet, O; Kosnik, M; Siegert, MW | 1 |
| Guo, L; Kuang, H; Lei, X; Liu, L; Xu, C; Xu, L | 1 |
| Li, B; Li, X; Zhang, J | 1 |
| Araújo, MRB; Sant'Anna, LO; Santos, LSD; Santos, NNCD; Seabra, LF | 1 |
| Han, Z; Li, Y; Lyu, C; Zhao, L; Zhou, M | 1 |
| Chakraborty, P; Karayi, M; Neppolian, B; Yazhini, C | 1 |
| Chen, G; Gao, H; Gu, J; Li, L; Ma, C; Yang, Z; Zhu, C | 1 |
| Ricky, R; Shanthakumar, S | 1 |
| Ganeshbabu, M; Manoj, GM; Priya, JS; Puneeth, NPN; Selvan, RK; Shankar, H; Shobana, C | 1 |
| Acuña-Askar, K; Guzmán-Mar, JL; Larralde-Piña, IA; Murillo-Sierra, JC; Ruiz-Ruiz, EJ; Villanueva-Rodríguez, M | 1 |
52 review(s) available for ciprofloxacin and norfloxacin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Recently reported biological activities of pyrazole compounds.
Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Pyrazoles | 2017 |
4-Quinolone derivatives and their activities against Gram positive pathogens.
Topics: 4-Quinolones; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 2018 |
Quinoline and quinolone dimers and their biological activities: An overview.
Topics: Anti-Bacterial Agents; Antimalarials; Antineoplastic Agents; Bacteria; Dimerization; Humans; Neoplasms; Quinolines; Quinolones | 2019 |
Benzofuran derivatives and their anti-tubercular, anti-bacterial activities.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Benzofurans; Humans; Structure-Activity Relationship | 2019 |
Fluoroquinolone-isatin hybrids and their biological activities.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Antitubercular Agents; Antiviral Agents; Fluoroquinolones; Humans; Isatin; Structure-Activity Relationship | 2019 |
Isatin derivatives and their anti-bacterial activities.
Topics: Anti-Bacterial Agents; Bacteria; Humans; Isatin; Structure-Activity Relationship | 2019 |
Quinolone hybrids and their anti-cancer activities: An overview.
Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Quinolones; Structure-Activity Relationship | 2019 |
Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles | 2019 |
Antibacterial activity study of 1,2,4-triazole derivatives.
Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles | 2019 |
Nitroimidazole-containing compounds and their antibacterial and antitubercular activities.
Topics: Anti-Bacterial Agents; Bacterial Infections; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Nitroimidazoles | 2019 |
Current scenario of tetrazole hybrids for antibacterial activity.
Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles | 2019 |
Quinolone antibiotics.
Topics: | 2019 |
New antibacterial drugs for topical ophthalmic use.
Topics: Ciprofloxacin; Conjunctivitis, Bacterial; Corneal Ulcer; Drug Therapy, Combination; Eye Infections, Bacterial; Humans; Norfloxacin; Ophthalmic Solutions; Polymyxin B; Trimethoprim | 1992 |
Prevention of infection in acute leukemia.
Topics: Acute Disease; Anti-Bacterial Agents; Ciprofloxacin; Colistin; Drug Therapy, Combination; Humans; Infection Control; Infections; Leukemia; Multicenter Studies as Topic; Neutropenia; Norfloxacin; Randomized Controlled Trials as Topic; Trimethoprim, Sulfamethoxazole Drug Combination | 1990 |
Pharmacokinetics of quinolones in renal insufficiency.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Glomerular Filtration Rate; Half-Life; Humans; Kidney Failure, Chronic; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1990 |
Safety profile of quinolones.
Topics: Animals; Ciprofloxacin; Dogs; Drug Tolerance; Humans; Male; Norfloxacin; Ofloxacin; Rats | 1990 |
Update on quinolone drug interactions.
Topics: Ciprofloxacin; Drug Interactions; Humans; Norfloxacin | 1990 |
[Prospects of clinical uses of quinolones in burn wound infections].
Topics: Animals; Anti-Infective Agents; Burns; Ciprofloxacin; Humans; Norfloxacin; Wound Infection | 1990 |
Clinical impact of newer quinolones: influence on normal microflora.
Topics: Bacterial Infections; Ciprofloxacin; Humans; Immune Tolerance; Intestinal Mucosa; Norfloxacin; Oropharynx; Recurrence; Urinary Tract Infections | 1989 |
Norfloxacin, ciprofloxacin, and ofloxacin: current clinical roles.
Topics: Bacteria; Bacterial Infections; Ciprofloxacin; Drug Tolerance; Humans; Norfloxacin; Ofloxacin | 1989 |
Action of quinolones on gene expression and bacterial membranes.
Topics: Animals; Anti-Bacterial Agents; Cell Membrane; Ciprofloxacin; Gene Expression Regulation; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines; SOS Response, Genetics; Topoisomerase II Inhibitors | 1987 |
The fluoroquinolones: pharmacology, clinical uses, and toxicities in humans.
Topics: Anti-Bacterial Agents; Bacteria; Blood Proteins; Ciprofloxacin; Enoxacin; Fluorine; Humans; Kidney; Kinetics; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Protein Binding; Quinolines; Urinary Tract Infections | 1985 |
Two new fluoroquinolones: ciprofloxacin and norfloxacin.
Topics: Bacterial Infections; Ciprofloxacin; Humans; Norfloxacin | 1988 |
Mechanisms of action of and resistance to ciprofloxacin.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Escherichia coli; Mutation; Nalidixic Acid; Norfloxacin; Topoisomerase II Inhibitors | 1987 |
Bacterial resistance to norfloxacin and other newer quinolones: pattern and prospects.
Topics: Ciprofloxacin; DNA, Bacterial; Drug Resistance, Microbial; Humans; Mutation; Norfloxacin; Quinolines | 1988 |
A review on the impact of 4-quinolones on the normal oropharyngeal and intestinal human microflora.
Topics: Ciprofloxacin; Enoxacin; Humans; Intestines; Naphthyridines; Norfloxacin; Ofloxacin; Oropharynx; Oxazines; Pefloxacin; Quinolines | 1988 |
Pharmacokinetics of ciprofloxacin.
Topics: Anti-Infective Agents; Biological Availability; Ciprofloxacin; Humans; Norfloxacin; Ofloxacin; Oxazines; Tissue Distribution | 1988 |
[Refractory respiratory tract infections. 7. Trends in the development of new chemotherapeutic agents for respiratory tract infections. b. Synthetic antibacterial agents].
Topics: 4-Quinolones; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Humans; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Quinolines; Respiratory Tract Infections | 1987 |
Ciprofloxacin and norfloxacin, two fluoroquinolone antimicrobials.
Topics: Ciprofloxacin; Humans; Norfloxacin | 1987 |
Symposium on antimicrobial agents. The quinolones.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Female; Humans; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1987 |
Quinolones.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Enoxacin; Humans; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
Ciprofloxacin in the treatment of gonorrhoea and non-gonococcal urethritis.
Topics: 4-Quinolones; Anti-Infective Agents; Anti-Infective Agents, Urinary; Chlamydia Infections; Chlamydia trachomatis; Ciprofloxacin; Gonorrhea; Humans; Norfloxacin; Quinolines; Quinolones; Urethritis | 1986 |
The mode of action of 4-quinolones and possible mechanisms of resistance.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Humans; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1986 |
New antibiotics: areas of appropriate use.
Topics: Anti-Bacterial Agents; Aztreonam; Bacterial Infections; beta-Lactamase Inhibitors; Cephalosporins; Ciprofloxacin; Enoxacin; Humans; Imipenem; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Thienamycins | 1987 |
The role of 4-quinolones in the treatment of infections.
Topics: Bacterial Infections; Ciprofloxacin; Humans; Kinetics; Norfloxacin; Ofloxacin; Oxazines; Urinary Tract Infections | 1987 |
Review of the 4-quinolones.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Interactions; Drug Resistance, Microbial; Enoxacin; Humans; Kinetics; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1987 |
Quinolone therapy in intensive care unit settings.
Topics: Administration, Oral; Aged; Ciprofloxacin; Clinical Protocols; Clinical Trials as Topic; Cross Infection; Drug Interactions; Drug Resistance, Microbial; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Intensive Care Units; Male; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Tissue Distribution | 1993 |
In-vitro activities of quinolones against mycobacteria.
Topics: Anti-Infective Agents; Ciprofloxacin; Humans; Microbial Sensitivity Tests; Mycobacterium leprae; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin | 1993 |
[Pharmacokinetics of fluoroquinolones].
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Humans; Norfloxacin; Ofloxacin; Pefloxacin | 1993 |
Fluoroquinolones reviewed.
Topics: Adult; Anti-Infective Agents; Child; Ciprofloxacin; Clinical Trials as Topic; Female; Humans; Norfloxacin; Ofloxacin; Urinary Tract Infections | 1993 |
Allergic nephropathy associated with norfloxacin and ciprofloxacin therapy. Report of two cases and review of the literature.
Topics: Aged; Anti-Infective Agents; Biopsy; Ciprofloxacin; Drug Hypersensitivity; Female; Humans; Kidney; Nephritis, Interstitial; Norfloxacin | 1997 |
[Current role of aminoglycosides in the treatment of acute pyelonephritis].
Topics: Acute Disease; Administration, Oral; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Cefadroxil; Cefotaxime; Cephalosporins; Ciprofloxacin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Gentamicins; Humans; Infusions, Intravenous; Inpatients; Male; Norfloxacin; Pyelonephritis; Recurrence; Time Factors; Tobramycin; Urinary Tract Infections | 1998 |
The expanding role of fluoroquinolones.
Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Urinary Tract Infections | 2002 |
Pediatric urinary tract infections: the role of fluoroquinolones.
Topics: Age Factors; Child; Child, Preschool; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluoroquinolones; Follow-Up Studies; Humans; Infant; Male; Norfloxacin; Randomized Controlled Trials as Topic; Risk Assessment; Severity of Illness Index; Treatment Outcome; Urinary Tract Infections | 2003 |
Quinolones for uncomplicated acute cystitis in women.
Topics: Acute Disease; Adult; Anti-Infective Agents, Urinary; Ciprofloxacin; Cystitis; Female; Fluoroquinolones; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Randomized Controlled Trials as Topic | 2006 |
[Bacterial infections in liver cirrhosis].
Topics: Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ascites; Bacteremia; Bacterial Infections; Cefotaxime; Cephalosporins; Ciprofloxacin; Fluoroquinolones; Gastrointestinal Hemorrhage; Humans; Infusions, Intravenous; Liver Cirrhosis; Norfloxacin; Peritonitis; Pneumonia, Bacterial; Primary Prevention; Severity of Illness Index; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections | 2007 |
Determination of four fluoroquinolone antibiotics in tap water in Guangzhou and Macao.
Topics: Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Water Pollutants, Chemical; Water Supply | 2010 |
Role of prophylactic antibiotics in cirrhotic patients with variceal bleeding.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Ciprofloxacin; Endoscopy; Esophageal and Gastric Varices; Fibrosis; Fluoroquinolones; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Norfloxacin; Practice Guidelines as Topic; Treatment Outcome | 2014 |
A systematic review of randomised clinical trials for oral antibiotic treatment of acute pyelonephritis.
Topics: Acute Disease; Administration, Oral; Anti-Bacterial Agents; Cephalosporins; Ciprofloxacin; Drug Combinations; Humans; Norfloxacin; Pyelonephritis; Randomized Controlled Trials as Topic; Sulfamethizole; Trimethoprim | 2018 |
Norfloxacin, ciprofloxacin, trimethoprim-sulfamethoxazole, and rifaximin for the prevention of spontaneous bacterial peritonitis: a network meta-analysis.
Topics: Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Humans; Network Meta-Analysis; Norfloxacin; Peritonitis; Rifaximin; Trimethoprim, Sulfamethoxazole Drug Combination | 2019 |
Globally Vibrio cholera antibiotics resistance to RNA and DNA effective antibiotics: A systematic review and meta-analysis.
Topics: Anti-Bacterial Agents; Cephalothin; Cholera; Cholera Toxin; Ciprofloxacin; Drug Resistance, Bacterial; Furazolidone; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Nalidixic Acid; Nitrofurantoin; Norfloxacin; Novobiocin; Rifampin; Vibrio cholerae; Virulence Factors | 2022 |
21 trial(s) available for ciprofloxacin and norfloxacin
| Article | Year |
|---|---|
Efficacy and tolerability of norfloxacin vs. ciprofloxacin in complicated urinary tract infection.
Topics: Ciprofloxacin; Drug Administration Schedule; Escherichia coli Infections; Female; Humans; Male; Middle Aged; Norfloxacin; Prospective Studies; Urinary Tract Infections | 1992 |
Prevention of bacterial infection in neutropenic patients with hematologic malignancies. A randomized, multicenter trial comparing norfloxacin with ciprofloxacin. The GIMEMA Infection Program. Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Female; Fever; Hematologic Diseases; Humans; Leukemia; Male; Middle Aged; Multivariate Analysis; Neutropenia; Norfloxacin | 1991 |
Prevention of infection in acute leukemia.
Topics: Acute Disease; Anti-Bacterial Agents; Ciprofloxacin; Colistin; Drug Therapy, Combination; Humans; Infection Control; Infections; Leukemia; Multicenter Studies as Topic; Neutropenia; Norfloxacin; Randomized Controlled Trials as Topic; Trimethoprim, Sulfamethoxazole Drug Combination | 1990 |
[Prophylaxis using quinolones in neutropenic patients. Preliminary results of a cooperative study by the Grupo Italiano Malattie Ematologiche maligne dell'adulto (GIMEMEA)].
Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Bone Marrow Transplantation; Ciprofloxacin; Disease Susceptibility; Female; Humans; Leukemia; Male; Multicenter Studies as Topic; Neutropenia; Norfloxacin; Prospective Studies; Random Allocation | 1989 |
Effect of quinolone antimicrobials on theophylline pharmacokinetics.
Topics: Adult; Ciprofloxacin; Half-Life; Humans; Male; Metabolic Clearance Rate; Nalidixic Acid; Norfloxacin; Random Allocation; Theophylline | 1989 |
4-quinolones inhibit biotransformation of caffeine.
Topics: Adult; Biotransformation; Caffeine; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Interactions; Enoxacin; Humans; Male; Molecular Structure; Norfloxacin; Ofloxacin; Pipemidic Acid; Quinolones; Random Allocation; Theophylline | 1988 |
Ocular penetration of topical ciprofloxacin and norfloxacin drops and their effect upon eyelid flora.
Topics: Administration, Topical; Aged; Aged, 80 and over; Aqueous Humor; Cataract Extraction; Ciprofloxacin; Colony Count, Microbial; Double-Blind Method; Eyelids; Female; Humans; Male; Middle Aged; Norfloxacin; Premedication; Prospective Studies; Staphylococcus | 1994 |
Safety of the new quinolones in pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Ciprofloxacin; Female; Humans; Infant, Newborn; Musculoskeletal Abnormalities; Norfloxacin; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, First; Prospective Studies | 1994 |
The effect of ferrous sulphate on the absorption of norfloxacin, ciprofloxacin and ofloxacin.
Topics: Absorption; Adult; Ciprofloxacin; Drug Interactions; Female; Ferrous Compounds; Humans; Male; Norfloxacin; Ofloxacin; Software | 1994 |
Penetration of topically applied ciprofloxacin, norfloxacin, and ofloxacin into the aqueous humor.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aqueous Humor; Biological Assay; Biological Availability; Cataract Extraction; Ciprofloxacin; Female; Humans; Lenses, Intraocular; Male; Middle Aged; Norfloxacin; Ofloxacin; Ophthalmic Solutions | 1994 |
Effective postcoital quinolone prophylaxis of recurrent urinary tract infections in women.
Topics: Adult; Ciprofloxacin; Coitus; Female; Humans; Norfloxacin; Ofloxacin; Prospective Studies; Recurrence; Urinary Tract Infections | 1994 |
Efficacy of ciprofloxacin and norfloxacin in multidrug resistant enteric fever in adults.
Topics: Adolescent; Adult; Ampicillin Resistance; Chloramphenicol Resistance; Ciprofloxacin; Drug Resistance, Microbial; Humans; Middle Aged; Norfloxacin; Typhoid Fever | 1993 |
Single dose quinolone treatment in acute uncomplicated urinary tract infection in women.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Ciprofloxacin; Female; Gram-Negative Bacterial Infections; Humans; Menopause; Middle Aged; Norfloxacin; Ofloxacin; Prospective Studies; Urinary Tract Infections | 1993 |
Comparative tear concentrations of topically applied ciprofloxacin, ofloxacin, and norfloxacin in human eyes.
Topics: Administration, Topical; Adult; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Eye; Female; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Spectrophotometry, Ultraviolet; Tears | 1997 |
Penetration of topically applied ciprofloxacin, norfloxacin and ofloxacin into the aqueous humor of the uninflamed human eye.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Aqueous Humor; Cataract Extraction; Ciprofloxacin; Eye Infections; Female; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Ophthalmic Solutions | 1997 |
Kinetics of 4-fluoroquinolones permeation into saliva.
Topics: Adult; Anti-Infective Agents; Biological Transport; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Monitoring; Humans; Male; Norfloxacin; Ofloxacin; Pefloxacin; Saliva | 1999 |
Single-dose ciprofloxacin versus 3 days of norfloxacin in uncomplicated urinary tract infections in women.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Female; Humans; Middle Aged; Norfloxacin; Treatment Outcome; Urinary Tract Infections | 2002 |
[Treatment of bacterial conjuntivitis with topical ciprofloxacin and norfloxacin: a comparative study].
Topics: Administration, Topical; Adult; Anti-Infective Agents; Ciprofloxacin; Conjunctivitis, Bacterial; Female; Humans; Male; Norfloxacin | 2003 |
Comparison of short-term treatment regimen of ciprofloxacin versus long-term treatment regimens of trimethoprim/sulfamethoxazole or norfloxacin for uncomplicated lower urinary tract infections: a randomized, multicentre, open-label, prospective study.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Administration Schedule; Female; Humans; Latin America; Norfloxacin; Premenopause; Prospective Studies; Sulfamethoxazole; Time Factors; Treatment Outcome; Trimethoprim; Urinary Tract Infections | 2004 |
Validation of a reversed-phase high-performance liquid chromatography method with fluorescence detection for the bioequivalence study of norfloxacin in plasma samples.
Topics: Anti-Bacterial Agents; Blood Proteins; Calibration; Chromatography, High Pressure Liquid; Ciprofloxacin; Cross-Over Studies; Double-Blind Method; Drugs, Generic; Humans; Indicators and Reagents; Norfloxacin; Quality Control; Reference Standards; Reproducibility of Results; Spectrometry, Fluorescence; Therapeutic Equivalency | 2008 |
Daily Norfloxacin vs. Weekly Ciprofloxacin to Prevent Spontaneous Bacterial Peritonitis: A Randomized Controlled Trial.
Topics: Adult; Aged; Anti-Bacterial Agents; Ascites; Bacterial Infections; Ciprofloxacin; Disease-Free Survival; Drug Administration Schedule; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Male; Middle Aged; Norfloxacin; Peritonitis; Republic of Korea; Treatment Outcome; Young Adult | 2018 |
745 other study(ies) available for ciprofloxacin and norfloxacin
| Article | Year |
|---|---|
Synthesis and structure-activity relationships of 7-diazabicycloalkylquinolones, including danofloxacin, a new quinolone antibacterial agent for veterinary medicine.
Topics: Actinobacillus Infections; Actinobacillus pleuropneumoniae; Aerobiosis; Anaerobiosis; Animals; Anti-Infective Agents; Bacterial Infections; Cattle; Cattle Diseases; Female; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Mice; Molecular Structure; Pasteurella Infections; Quinolones; Structure-Activity Relationship; Swine; Swine Diseases | 1992 |
Fluoroquinolones: relationships between structural variations, mammalian cell cytotoxicity, and antimicrobial activity.
Topics: Animals; Anti-Infective Agents; Cricetinae; Cricetulus; Fluoroquinolones; Microbial Sensitivity Tests; Structure-Activity Relationship | 1992 |
New 8-(trifluoromethyl)-substituted quinolones. The benefits of the 8-fluoro group with reduced phototoxic risk.
Topics: 4-Quinolones; Administration, Oral; Animals; Anti-Infective Agents; Bacterial Infections; Female; Injections, Subcutaneous; Mice; Microbial Sensitivity Tests; Photosensitivity Disorders; Structure-Activity Relationship | 1992 |
Synthesis and biological activity of 5-amino- and 5-hydroxyquinolones, and the overwhelming influence of the remote N1-substituent in determining the structure-activity relationship.
Topics: Alkylation; Aminoquinolines; Animals; Anti-Bacterial Agents; Bacterial Infections; Chemical Phenomena; Chemistry; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydroxyquinolines; Mice; Microbial Sensitivity Tests; Molecular Structure; Piperazines; Pyrrolidines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1991 |
Three-dimensional structure-activity relationships and receptor mapping of N1-substituents of quinolone antibacterials.
Topics: 4-Quinolones; Anti-Infective Agents; Computer Simulation; Escherichia coli; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Molecular Structure; Receptors, Drug; Software; Structure-Activity Relationship | 1991 |
Synthesis and biological activity of 5-alkyl-1,7,8-trisubstituted-6-fluoroquinoline-3-carboxylic acids.
Topics: 4-Quinolones; Anti-Infective Agents; Chemical Phenomena; Chemistry; Gram-Negative Bacteria; Gram-Positive Bacteria; Methylation; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 1991 |
Synthesis of antimicrobial agents. 3. Syntheses and antibacterial activities of 7-(4-hydroxypiperazin-1-yl)quinolones.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Chemical Phenomena; Chemistry, Physical; Drug Design; Injections, Intravenous; Mice; Piperazines; Quinolones; Structure-Activity Relationship | 1990 |
Fluoronaphthyridines and quinolones as antibacterial agents. 2. Synthesis and structure-activity relationships of new 1-tert-butyl 7-substituted derivatives.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Chemical Phenomena; Chemistry; Dogs; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Metabolic Clearance Rate; Mice; Microbial Sensitivity Tests; Naphthyridines; Structure-Activity Relationship | 1990 |
Quinolone antibacterial agents substituted at the 7-position with spiroamines. Synthesis and structure-activity relationships.
Topics: Bacteria; Chemical Phenomena; Chemistry; Gram-Negative Bacteria; Gram-Positive Bacteria; Molecular Structure; Piperazines; Pyrrolidines; Quinolines; Spiro Compounds; Structure-Activity Relationship | 1990 |
1-Substituted 7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8- difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids. New quantitative structure-activity relationships at N1 for the quinolone antibacterials.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Carboxylic Acids; Chemical Phenomena; Chemistry; Mice; Microbial Sensitivity Tests; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1988 |
Fluoronaphthyridines and quinolones as antibacterial agents. 1. Synthesis and structure-activity relationships of new 1-substituted derivatives.
Topics: 4-Quinolones; Animals; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Dogs; Gram-Negative Bacteria; Mice; Microbial Sensitivity Tests; Molecular Structure; Naphthyridines; Staphylococcus; Structure-Activity Relationship | 1989 |
New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay.
Topics: Anti-Bacterial Agents; Bacteria; DNA, Bacterial; DNA, Superhelical; Escherichia coli; Microbial Sensitivity Tests; Naphthyridines; Plasmids; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1986 |
1-Ethyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4- dihydro-4-oxo-3-quinoline-carboxylic acid. New quinolone antibacterial with potent gram-positive activity.
Topics: Animals; Anti-Bacterial Agents; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Naphthyridines; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1986 |
Chiral DNA gyrase inhibitors. 1. Synthesis and antimicrobial activity of the enantiomers of 6-fluoro-7-(1-piperazinyl)-1-(2'-trans-phenyl-1'-cyclopropyl)-1, 4-dihydro-4-oxoquinoline-3-carboxylic acid.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Fluoroquinolones; Stereoisomerism; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1986 |
Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride.
Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Solubility; Stereoisomerism; Structure-Activity Relationship | 1988 |
Synthesis and structure-activity relationships of new arylfluoronaphthyridine antibacterial agents.
Topics: Anti-Bacterial Agents; Bacteria; Fluorine; Naphthyridines; Structure-Activity Relationship | 1986 |
Synthesis and structure-activity relationship of 1-aryl-6,8-difluoroquinolone antibacterial agents.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Female; Fluorine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Microbial Sensitivity Tests; Quinolines; Spectrophotometry, Infrared; Structure-Activity Relationship | 1987 |
Synthesis and antibacterial activity of some novel 1-substituted 1,4-dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic acids. Potent antistaphylococcal agents.
Topics: Anti-Bacterial Agents; Bacillus; Carboxylic Acids; Enterococcus faecalis; Pseudomonas aeruginosa; Staphylococcus aureus; Streptococcus pneumoniae; Structure-Activity Relationship | 1995 |
Quinolone antimicrobial agents substituted with morpholines at the 7-position. Syntheses and structure-activity relationships.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Escherichia coli; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Morpholines; Quinolones; Staphylococcus aureus; Structure-Activity Relationship | 1993 |
Synthesis of antimicrobial agents. 5. In vivo metabolism of 7-(4-hydroxypiperazin-1-yl)quinolones.
Topics: 4-Quinolones; Administration, Oral; Animals; Anti-Infective Agents; Mice; Microbial Sensitivity Tests; Piperazines; Rats; Structure-Activity Relationship | 1993 |
Structure-activity relationships of the quinolone antibacterials against mycobacteria: effect of structural changes at N-1 and C-7.
Topics: Anti-Bacterial Agents; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Mycobacterium; Spectrophotometry, Infrared; Structure-Activity Relationship | 1996 |
New bronchodilators selected by molecular topology.
Topics: Animals; Bronchodilator Agents; Discriminant Analysis; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Structure-Activity Relationship; Trachea | 1998 |
Novel quinolone derivatives as potent antibacterials.
Topics: Anti-Bacterial Agents; Bacteria; Microbial Sensitivity Tests; Quinolones; Species Specificity; Structure-Activity Relationship | 1998 |
Artificial neural network applied to prediction of fluorquinolone antibacterial activity by topological methods.
Topics: Algorithms; Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Neural Networks, Computer; Structure-Activity Relationship | 2000 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
New pyridoquinoline derivatives as potential inhibitors of the fluoroquinolone efflux pump in resistant Enterobacter aerogenes strains.
Topics: Anti-Infective Agents; Bacterial Proteins; DNA-Binding Proteins; Drug Antagonism; Drug Resistance, Bacterial; Drug Resistance, Multiple; Enterobacter aerogenes; Escherichia coli Proteins; Microbial Sensitivity Tests; Norfloxacin; Quinolines; Structure-Activity Relationship; Thermodynamics | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Piperazinyl-linked fluoroquinolone dimers possessing potent antibacterial activity against drug-resistant strains of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cross-Linking Reagents; Dimerization; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Piperazines; Staphylococcus aureus; Structure-Activity Relationship | 2003 |
Search compounds with antimicrobial activity by applying molecular topology to selected quinolones.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Discriminant Analysis; Drug Design; Microbial Sensitivity Tests; Quantitative Structure-Activity Relationship; Quinolones | 2003 |
Synthesis of stavudine amino acid ester prodrugs with broad-spectrum chemotherapeutic properties for the effective treatment of HIV/AIDS.
Topics: Amino Acids; Anti-Bacterial Agents; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Esters; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Prodrugs; Stavudine | 2004 |
Inhibitors of multidrug resistance (MDR) have affinity for MDR substrates.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Cell Membrane; Drug Resistance, Microbial; Drug Resistance, Multiple; Ligands; Models, Molecular | 2004 |
Chemometric studies on the bactericidal activity of quinolones via an extended VolSurf approach.
Topics: Anti-Bacterial Agents; Enterococcus faecalis; Escherichia coli; Models, Molecular; Pseudomonas aeruginosa; Quantitative Structure-Activity Relationship; Quinolones; Staphylococcus aureus; Thermodynamics | 2004 |
A chiral benzoquinolizine-2-carboxylic acid arginine salt active against vancomycin-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Clinical Trials, Phase I as Topic; Dogs; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Half-Life; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Mutation; Prodrugs; Quinolizines; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship; Vancomycin Resistance | 2005 |
Synthesis and antibacterial activity of N-(5-benzylthio-1,3,4-thiadiazol-2-yl) and N-(5-benzylsulfonyl-1,3,4-thiadiazol-2-yl)piperazinyl quinolone derivatives.
Topics: Anti-Bacterial Agents; Microbial Sensitivity Tests; Quinolones; Staphylococcus aureus; Staphylococcus epidermidis; Structure-Activity Relationship | 2005 |
Synthesis and antibacterial activity of 3-substituted-6-(3-ethyl-4-methylanilino)uracils.
Topics: Aniline Compounds; Animals; Anti-Bacterial Agents; DNA Polymerase III; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship; Uracil | 2005 |
Isothiazolopyridones: synthesis, structure, and biological activity of a new class of antibacterial agents.
Topics: Anti-Bacterial Agents; Crystallography, X-Ray; DNA Topoisomerase IV; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Pyridones; Structure-Activity Relationship; Thiazoles; Topoisomerase II Inhibitors | 2006 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hybrid antibacterials. DNA polymerase-topoisomerase inhibitors.
Topics: Aniline Compounds; Animals; Anti-Bacterial Agents; DNA Polymerase III; Drug Resistance, Bacterial; Gram-Positive Bacteria; Male; Mice; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship; Topoisomerase II Inhibitors; Toxicity Tests, Acute; Uracil | 2006 |
Synthesis and antibacterial activity of new fluoroquinolones containing a substituted N-(phenethyl)piperazine moiety.
Topics: Anti-Bacterial Agents; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; In Vitro Techniques; Microbial Sensitivity Tests; Molecular Structure; Piperazines; Stereoisomerism; Structure-Activity Relationship | 2006 |
An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus.
Topics: Bacterial Proteins; Cysteine; Hydrogen Peroxide; Oxidation-Reduction; Protein Conformation; Protein Structure, Tertiary; Repressor Proteins; Staphylococcus aureus | 2006 |
Effect of anaerobic growth on quinolone lethality with Escherichia coli.
Topics: Aerobiosis; Anaerobiosis; Anti-Infective Agents; Chloramphenicol; Ciprofloxacin; DNA Fragmentation; DNA Gyrase; DNA, Bacterial; DnaB Helicases; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Escherichia coli; Microbial Sensitivity Tests; Models, Biological; Molecular Structure; Nalidixic Acid; Quinolones | 2007 |
Synthesis of omeprazole analogues and evaluation of these as potential inhibitors of the multidrug efflux pump NorA of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Culture Media; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Indicators and Reagents; Kinetics; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Norfloxacin; Omeprazole; Staphylococcus aureus; Structure-Activity Relationship | 2007 |
First characterization of fluoroquinolone resistance in Streptococcus suis.
Topics: Amino Acid Sequence; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Female; Fluoroquinolones; Genes, Bacterial; Humans; Male; Molecular Sequence Data; Point Mutation; RNA, Ribosomal, 16S; Sequence Alignment; Streptococcus suis | 2007 |
Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Drug Resistance, Bacterial; Humans; Longitudinal Studies; Pneumonia, Ventilator-Associated; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections | 2007 |
Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal.
Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Middle Aged; Portugal | 2007 |
Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains.
Topics: Anti-Bacterial Agents; Drug Design; Drug Resistance, Multiple; Enzyme Inhibitors; Indazoles; Microbial Sensitivity Tests; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2007 |
Vibrio splendidus as the source of plasmid-mediated QnrS-like quinolone resistance determinants.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Computer Simulation; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleic Acid Amplification Techniques; Open Reading Frames; Plasmids; Polymerase Chain Reaction; Quinolones; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Vibrio | 2007 |
Transferable resistance to aminoglycosides by methylation of G1405 in 16S rRNA and to hydrophilic fluoroquinolones by QepA-mediated efflux in Escherichia coli.
Topics: Amino Acid Motifs; Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Conjugation, Genetic; Conserved Sequence; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Genes, rRNA; Methylation; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Norfloxacin; Plasmids; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2007 |
Plasmid-mediated quinolone resistance determinant QnrB4 identified in France in an Enterobacter cloacae clinical isolate coexpressing a QnrS1 determinant.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Child, Preschool; Conjugation, Genetic; Drug Resistance, Bacterial; Enterobacter cloacae; Escherichia coli; France; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Plasmids; Quinolones; Transformation, Genetic | 2007 |
New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chitosan; Conjugation, Genetic; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Humans; Malates; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Transformation, Bacterial; Uncoupling Agents | 2007 |
In vitro susceptibilities of Mycoplasma putrefaciens field isolates.
Topics: Anti-Bacterial Agents; France; Humans; Jordan; Lincomycin; Macrolides; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma Infections; Tetracycline Resistance | 2007 |
Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate.
Topics: Bacterial Proteins; Base Sequence; beta-Lactamases; Carrier Proteins; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Genes, MDR; Genetic Vectors; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Porins | 2007 |
Contributions of the combined effects of topoisomerase mutations toward fluoroquinolone resistance in Escherichia coli.
Topics: DNA Topoisomerases; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Mutation | 2007 |
Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gene Expression Regulation, Bacterial; Heat-Shock Proteins; Microbial Sensitivity Tests; Oligonucleotide Array Sequence Analysis; Protease La; Pseudomonas aeruginosa | 2007 |
Complex class 1 integrons with diverse variable regions, including aac(6')-Ib-cr, and a novel allele, qnrB10, associated with ISCR1 in clinical enterobacterial isolates from Argentina.
Topics: Alleles; Amino Acid Sequence; Argentina; Bacterial Proteins; Base Sequence; beta-Lactamases; Cross Infection; DNA Transposable Elements; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid | 2007 |
Reduced Susceptibility of Proteus mirabilis to triclosan.
Topics: Anti-Infective Agents, Local; Biofilms; Colony Count, Microbial; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Models, Anatomic; Mutation; Proteus mirabilis; Triclosan; Urinary Bladder; Urinary Catheterization | 2008 |
Synthesis of new 4-pyrrol-1-yl benzoic acid hydrazide analogs and some derived oxadiazole, triazole and pyrrole ring systems: a novel class of potential antibacterial and antitubercular agents.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Benzoic Acid; Drug Design; Mycobacterium tuberculosis; Oxadiazoles; Pyrroles; Triazoles | 2008 |
Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa.
Topics: Aminoglycosides; Anti-Bacterial Agents; Carbenicillin; Ceftazidime; Ciprofloxacin; Drug Resistance, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Novobiocin; Ofloxacin; Piperacillin; Polyethyleneimine; Pseudomonas aeruginosa; Pseudomonas Infections; Rifampin; Ticarcillin; Tobramycin | 2008 |
Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan.
Topics: Anti-Bacterial Agents; Conjugation, Genetic; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Fluoroquinolones; Hospitals; Humans; Japan; Microbial Sensitivity Tests; Plasmids; Prevalence | 2008 |
Coprevalence of plasmid-mediated quinolone resistance determinants QepA, Qnr, and AAC(6')-Ib-cr among 16S rRNA methylase RmtB-producing Escherichia coli isolates from pigs.
Topics: Animals; Anti-Bacterial Agents; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Methyltransferases; Plasmids; RNA, Ribosomal, 16S; Swine; Swine Diseases | 2008 |
Plasmid-mediated QnrS2 determinant from a clinical Aeromonas veronii isolate.
Topics: Aeromonas; Ciprofloxacin; Drug Resistance, Bacterial; Genes, Bacterial; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Plasmids; Quinolones | 2008 |
Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey.
Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Turkey | 2008 |
ISEcp1-mediated transposition of qnrB-like gene in Escherichia coli.
Topics: Base Sequence; DNA Transposable Elements; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Microbial Sensitivity Tests; Molecular Sequence Data; Quinolones | 2008 |
Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Bacteria; Bacterial Infections; Bacterial Proteins; Cell Line; Cell Proliferation; Metabolic Clearance Rate; Mice; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Stereoisomerism; Topoisomerase II Inhibitors | 2008 |
Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli.
Topics: Anti-Bacterial Agents; Antiporters; ATP-Binding Cassette Transporters; Bacterial Proteins; Cloning, Molecular; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Ethidium; Fluorescence Polarization; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin | 2008 |
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.
Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids | 2008 |
Smqnr, a new chromosome-carried quinolone resistance gene in Stenotrophomonas maltophilia.
Topics: Alleles; Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Chromosomes, Bacterial; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Genes, Bacterial; Gram-Negative Bacterial Infections; Humans; Molecular Sequence Data; Sequence Homology, Amino Acid; Stenotrophomonas maltophilia | 2008 |
RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine.
Topics: Anti-Bacterial Agents; Antipsychotic Agents; Bacterial Proteins; Base Sequence; Chlorpromazine; DNA Primers; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Synergism; Ethidium; Gene Expression; Genes, Bacterial; Humans; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Oligonucleotide Array Sequence Analysis; Phenothiazines; Salmonella typhimurium; Trans-Activators | 2008 |
Real-time PCR detection of gyrA and parC mutations in Streptococcus pneumoniae.
Topics: Amino Acid Substitution; Base Sequence; DNA Gyrase; DNA Mutational Analysis; DNA Primers; DNA Probes; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Genes, Bacterial; Humans; Nucleic Acid Denaturation; Point Mutation; Polymerase Chain Reaction; Streptococcus pneumoniae; Thermodynamics | 2008 |
Mechanisms accounting for fluoroquinolone resistance in Escherichia coli clinical isolates.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Escherichia coli; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Norfloxacin; Ofloxacin | 2009 |
Relationships among ciprofloxacin, gatifloxacin, levofloxacin, and norfloxacin MICs for fluoroquinolone-resistant Escherichia coli clinical isolates.
Topics: Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; United States | 2009 |
Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates.
Topics: Anti-Bacterial Agents; beta-Lactamases; Conjugation, Genetic; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Escherichia coli; Humans; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA; Transformation, Bacterial | 2008 |
Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog.
Topics: Animals; Anti-Bacterial Agents; Dogs; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Humans; Plasmids; Virulence | 2009 |
qnrD, a novel gene conferring transferable quinolone resistance in Salmonella enterica serovar Kentucky and Bovismorbificans strains of human origin.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Cattle; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Quinolones; Salmonella enterica | 2009 |
Contribution of oxidative damage to antimicrobial lethality.
Topics: 2,2'-Dipyridyl; Anti-Bacterial Agents; Bacterial Proteins; Catalase; Escherichia coli; Escherichia coli Proteins; Hydroxyl Radical; Microbial Sensitivity Tests; Norfloxacin; Oxidative Stress; Superoxide Dismutase; Thiourea | 2009 |
Targeted delivery of compounds to Trypanosoma brucei using the melamine motif.
Topics: Animals; Eflornithine; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Triazines; Trypanocidal Agents; Trypanosoma brucei brucei | 2009 |
Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea.
Topics: Acetyltransferases; beta-Lactamases; Ciprofloxacin; Conjugation, Genetic; Enterobacteriaceae; Microbial Sensitivity Tests; Plasmids | 2009 |
First detection of plasmid-encoded blaOXY beta-lactamase.
Topics: beta-Lactamases; Blotting, Southern; Child, Preschool; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Klebsiella; Klebsiella oxytoca; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction | 2009 |
Emergence of quinolone-resistant Bordetella pertussis in Japan.
Topics: Anti-Bacterial Agents; Bordetella pertussis; Child; DNA Gyrase; Fluoroquinolones; Humans; Japan; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Quinolones | 2009 |
Characterization of the plasmid-borne quinolone resistance gene qnrB19 in Salmonella enterica serovar Typhimurium.
Topics: Anti-Bacterial Agents; Bacterial Proteins; DNA Transposable Elements; Drug Resistance, Multiple, Bacterial; Evolution, Molecular; Microbial Sensitivity Tests; Multigene Family; Plasmids; Quinolones; Salmonella typhimurium | 2009 |
Interaction of drug based binuclear mixed-ligand complexes with DNA.
Topics: Anti-Bacterial Agents; Bacteria; Binding Sites; Ciprofloxacin; Cobalt; DNA, Bacterial; Ligands; Magnetic Resonance Spectroscopy; Magnetics; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Structure; Oxidation-Reduction; Spectrophotometry, Infrared; Structure-Activity Relationship; Temperature; Viscosity | 2009 |
CraA, a major facilitator superfamily efflux pump associated with chloramphenicol resistance in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Chloramphenicol Resistance; Drug Resistance, Multiple, Bacterial; Imipenem; Microbial Sensitivity Tests; Polymerase Chain Reaction; Quinolones; Tetracyclines | 2009 |
Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs.
Topics: Antitubercular Agents; Disinfectants; Drug Resistance, Bacterial; Glutaral; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Mycobacterium chelonae; Mycobacterium smegmatis; o-Phthalaldehyde; Porins | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Synthesis of new 4-isopropylthiazole hydrazide analogs and some derived clubbed triazole, oxadiazole ring systems--a novel class of potential antibacterial, antifungal and antitubercular agents.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antitubercular Agents; Bacteria; Cell Line, Tumor; Cell Survival; Fungi; Humans; Hydrazines; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Thiazoles | 2009 |
7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Ciprofloxacin; Humans; Maximum Tolerated Dose; Mice; Neoplasms; Piperazine; Piperazines | 2009 |
Mechanisms of resistance in nontyphoidal Salmonella enterica strains exhibiting a nonclassical quinolone resistance phenotype.
Topics: Bacterial Proteins; Drug Resistance, Bacterial; Electroporation; Genotype; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Quinolones; Salmonella enterica | 2009 |
High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali.
Topics: beta-Lactamases; Drug Resistance, Bacterial; Enterobacteriaceae; Humans; Random Amplified Polymorphic DNA Technique | 2009 |
Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR.
Topics: Microbial Sensitivity Tests; Mycoplasma genitalium; Polymerase Chain Reaction | 2009 |
Role of AbeS, a novel efflux pump of the SMR family of transporters, in resistance to antimicrobial agents in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Multiple, Bacterial; Escherichia coli; Membrane Transport Proteins; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Homology, Amino Acid | 2009 |
Prevalence and clonal characterization of Streptococcus pyogenes clinical isolates with reduced fluoroquinolone susceptibility in Spain.
Topics: Adult; Anti-Bacterial Agents; Child; Drug Resistance, Bacterial; Female; Fluoroquinolones; Genes, Bacterial; Humans; Male; Microbial Sensitivity Tests; Mutation; Prospective Studies; Spain; Streptococcal Infections; Streptococcus pyogenes | 2010 |
Relative contributions of active mediated transport and passive diffusion of fluoroquinolones with various lipophilicities in a Calu-3 lung epithelial cell model.
Topics: Absorption; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport, Active; Cell Line; Cell Membrane Permeability; Cyclosporins; Diffusion; Drug Interactions; Drug Resistance, Bacterial; Epithelial Cells; Fluoroquinolones; Kinetics; Lipids; Lung | 2010 |
Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; DNA, Bacterial; DNA, Complementary; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Genes, MDR; Metals, Heavy; Microbial Sensitivity Tests; Mutation; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Bacterial | 2010 |
The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability.
Topics: Caco-2 Cells; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Membranes, Artificial; Molecular Structure; Pharmaceutical Preparations | 2010 |
Constitutive SoxS expression in a fluoroquinolone-resistant strain with a truncated SoxR protein and identification of a new member of the marA-soxS-rob regulon, mdtG.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Gene Expression Regulation, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Regulon; Sequence Analysis, DNA; Trans-Activators; Transcription Factors | 2010 |
Characterization of small ColE-like plasmids mediating widespread dissemination of the qnrB19 gene in commensal enterobacteria.
Topics: Anti-Bacterial Agents; DNA Transposable Elements; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Genotype; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Quinolones | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents.
Topics: Anti-Bacterial Agents; Campylobacter coli; Campylobacter Infections; Campylobacter jejuni; Carbapenems; Drug Resistance, Multiple, Bacterial; Erythromycin; Feces; Finland; Humans; Macrolides; Microbial Sensitivity Tests; Minocycline; Tigecycline | 2010 |
Synthesis of some novel 2-substituted-5-[isopropylthiazole] clubbed 1,2,4-triazole and 1,3,4-oxadiazoles as potential antimicrobial and antitubercular agents.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Antitubercular Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Triazoles | 2010 |
In vitro antibacterial activities of JNJ-Q2, a new broad-spectrum fluoroquinolone.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Design; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Methicillin-Resistant Staphylococcus aureus; Streptococcus pneumoniae | 2010 |
Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Cell Membrane Permeability; Cells, Cultured; Drug Resistance, Bacterial; Endosomes; Escherichia coli; Escherichia coli Infections; Female; Humans; Mice; Mice, Inbred CBA; Microbial Sensitivity Tests; Recurrence; Urinary Bladder; Urinary Tract Infections; Urothelium | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Novel variants of the qnrB gene, qnrB22 and qnrB23, in Citrobacter werkmanii and Citrobacter freundii.
Topics: Animals; Bacterial Proteins; Chickens; Citrobacter; Citrobacter freundii; Escherichia coli; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Quinolones; Swine | 2010 |
The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Burkholderia pseudomallei; Culture Media; Drug Resistance, Multiple, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; Periplasmic Proteins; Quorum Sensing; Singapore; Virulence Factors | 2010 |
Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates.
Topics: Anti-Bacterial Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chlortetracycline; Dipeptides; Doxorubicin; Doxycycline; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Minocycline; Onium Compounds; Organophosphorus Compounds; Tetracycline | 2010 |
Fluoroquinolone efflux by the plasmid-mediated multidrug efflux pump QacB variant QacBIII in Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Fluoroquinolones; Membrane Transport Proteins; Plasmids; Staphylococcus aureus | 2010 |
Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment.
Topics: Animals; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Quinolones | 2010 |
Synthesis and antimicrobial activity of novel fluorine containing 4-(substituted-2-hydroxybenzoyl)-1H-pyrazoles and pyrazolyl benzo[d]oxazoles.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Bacillus subtilis; Bacteria; Bacterial Infections; Candida albicans; Candidiasis; Escherichia coli; Fluorine; Humans; Microbial Sensitivity Tests; Oxazoles; Pseudomonas aeruginosa; Pyrazoles; Staphylococcus aureus; Structure-Activity Relationship | 2010 |
Synthesis and pharmacological evaluation of clubbed isopropylthiazole derived triazolothiadiazoles, triazolothiadiazines and mannich bases as potential antimicrobial and antitubercular agents.
Topics: Anti-Infective Agents; Antitubercular Agents; Bacteria; Fungi; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Spectrophotometry, Infrared; Thiazoles | 2010 |
Reduced expression of the vca0421 gene of Vibrio cholerae O1 results in innate resistance to ciprofloxacin.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Fluoroquinolones; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Vibrio cholerae O1 | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Bernthsen synthesis, antimicrobial activities and cytotoxicity of acridine derivatives.
Topics: Acridines; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antineoplastic Agents; Aspergillus niger; Bacteria; Gram-Negative Bacteria; Gram-Positive Bacteria; Indicators and Reagents; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Spectrophotometry, Infrared | 2010 |
Synthesis and in vitro antimicrobial evaluation of novel fluoroquinolone derivatives.
Topics: Anti-Bacterial Agents; Antifungal Agents; Candida albicans; Cryptococcus neoformans; Fluoroquinolones; Microbial Sensitivity Tests; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2010 |
Overexpression of patA and patB, which encode ABC transporters, is associated with fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae.
Topics: Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Microbial Sensitivity Tests; Polymerase Chain Reaction; Streptococcus pneumoniae | 2011 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
In vitro effect of qnrA1, qnrB1, and qnrS1 genes on fluoroquinolone activity against isogenic Escherichia coli isolates with mutations in gyrA and parC.
Topics: Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Microbial Sensitivity Tests; Mutation | 2011 |
Synthesis and antibacterial evaluation of novel 8-fluoro Norfloxacin derivatives as potential probes for methicillin and vancomycin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Drug Interactions; Fluorenes; Fluorobenzenes; Folic Acid Antagonists; Klebsiella pneumoniae; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Norfloxacin; Tetrahydrofolate Dehydrogenase; Vancomycin Resistance | 2011 |
New fluorine-containing hydrazones active against MDR-tuberculosis.
Topics: Animals; Antitubercular Agents; Cell Line; Fluorine; Humans; Hydrazones; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium kansasii; Plasma; Rats; Tuberculosis, Multidrug-Resistant | 2011 |
Preparation and antibacterial evaluation of decarboxylated fluoroquinolones.
Topics: Anti-Bacterial Agents; Carboxylic Acids; Drug Design; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Structure-Activity Relationship | 2011 |
Microwave assisted synthesis and antimicrobial evaluation of new fused pyran derivatives bearing 2-morpholinoquinoline nucleus.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Candida albicans; Fungi; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Microwaves; Mycoses; Pyrans; Quinolines | 2011 |
1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study.
Topics: Antifungal Agents; Antitubercular Agents; Chemistry Techniques, Synthetic; Drug Design; Fungi; Indoles; Microbial Sensitivity Tests; Mycobacterium tuberculosis | 2011 |
Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics.
Topics: Anti-Bacterial Agents; beta-Lactams; Computational Biology; Drug Resistance, Bacterial; Hydrophobic and Hydrophilic Interactions; Ligands; Membrane Transport Proteins; Microbial Sensitivity Tests; Models, Molecular; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Regression Analysis; Thermodynamics | 2012 |
An efficient one-pot synthesis, structure, antimicrobial and antioxidant investigations of some novel quinolyldibenzo[b,e][1,4]diazepinones.
Topics: Anti-Infective Agents; Antioxidants; Azepines; Crystallography, X-Ray; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Conformation; Quinolines | 2012 |
An improved microwave assisted one-pot synthesis, and biological investigations of some novel aryldiazenyl chromeno fused pyrrolidines.
Topics: Antifungal Agents; Antitubercular Agents; Aspergillus fumigatus; Azo Compounds; Benzopyrans; Candida albicans; Crystallography, X-Ray; Gram-Negative Bacteria; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microwaves; Molecular Structure; Mycobacterium tuberculosis; Pyrrolidines; Stereoisomerism; Thiosemicarbazones | 2012 |
New N-arylamino biquinoline derivatives: synthesis, antimicrobial, antituberculosis, and antimalarial evaluation.
Topics: Antimalarials; Antitubercular Agents; Chemistry Techniques, Synthetic; Electrons; Fungi; Hydrophobic and Hydrophilic Interactions; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Plasmodium falciparum; Quinolines | 2012 |
Green synthesis and anti-infective activities of fluorinated pyrazoline derivatives.
Topics: Anti-Infective Agents; Antitubercular Agents; Bacteria; Bacterial Infections; Fungi; Green Chemistry Technology; Halogenation; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Mycoses; Pyrazoles; Tuberculosis | 2012 |
An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles.
Topics: Aldehydes; Anti-Bacterial Agents; Coumarins; Gram-Negative Bacteria; Gram-Positive Bacteria; Heterocyclic Compounds; Ionic Liquids; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrans; Pyrazolones; Quinolines; Structure-Activity Relationship | 2013 |
Synthesis and identification of β-aryloxyquinoline based diversely fluorine substituted N-aryl quinolone derivatives as a new class of antimicrobial, antituberculosis and antioxidant agents.
Topics: Animals; Anti-Infective Agents; Antioxidants; Antitubercular Agents; Artemia; Aspergillus fumigatus; Candida albicans; Dose-Response Relationship, Drug; Fluorine; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Models, Chemical; Molecular Structure; Mycobacterium tuberculosis; Ovum; Quinolines; Structure-Activity Relationship | 2013 |
Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents.
Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Benzoxazines; Dose-Response Relationship, Drug; Fungi; Microbial Sensitivity Tests; Molecular Structure; Piperidines; Structure-Activity Relationship | 2013 |
Design and synthesis of biquinolone-isoniazid hybrids as a new class of antitubercular and antimicrobial agents.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antitubercular Agents; Artemia; Bacteria; Dose-Response Relationship, Drug; Drug Design; Fungi; Isoniazid; Microbial Sensitivity Tests; Molecular Structure; Motor Activity; Quinolones; Structure-Activity Relationship; Tuberculosis | 2013 |
Antimicrobial activity of imidazo[1,5-a]quinoxaline derivatives with pyridinium moiety.
Topics: Animals; Anti-Infective Agents; Bacteria; Drug Design; Female; Fungi; Imidazoles; Male; Mice; Microbial Sensitivity Tests; Pyridinium Compounds | 2013 |
Synthesis and study of 1-ethyl-3-carbohydrazide and 3-[1-oxo-2-hydrazino-3-{p-toluenesulfon}]quinolone derivatives against bacterial infections.
Topics: Anti-Bacterial Agents; Bacterial Infections; Dose-Response Relationship, Drug; Escherichia coli; Hydrazines; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Quinolones; Salmonella typhi; Staphylococcus aureus; Structure-Activity Relationship | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Synthesis and antibacterial evaluation of amino acid-antibiotic conjugates.
Topics: Amino Acids; Anti-Bacterial Agents; Bacillus subtilis; Dose-Response Relationship, Drug; Escherichia coli; Metronidazole; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Structure-Activity Relationship; Sulfadiazine | 2014 |
Synthesis, characterization and pharmacological screening of some novel 5-imidazopyrazole incorporated polyhydroquinoline derivatives.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Bacteria; Dose-Response Relationship, Drug; Fungi; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymers; Pyrazoles; Quinolines; Structure-Activity Relationship | 2014 |
Design, synthesis, and biological evaluation of dihydroartemisinin-fluoroquinolone conjugates as a novel type of potential antitubercular agents.
Topics: Antitubercular Agents; Artemisinins; Drug Design; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2014 |
Design, synthesis and characterization of fluoro substituted novel pyrazolylpyrazolines scaffold and their pharmacological screening.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Bacteria; Dose-Response Relationship, Drug; Drug Design; Fungi; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrazoles; Structure-Activity Relationship | 2014 |
Boronic species as promising inhibitors of the Staphylococcus aureus NorA efflux pump: study of 6-substituted pyridine-3-boronic acid derivatives.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Boronic Acids; Ciprofloxacin; Humans; KB Cells; Multidrug Resistance-Associated Proteins; Pyridines; Staphylococcal Infections; Staphylococcus aureus | 2015 |
Design and biological evaluation of novel quinolone-based metronidazole derivatives as potent Cu(2+) mediated DNA-targeting antibacterial agents.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Chemistry Techniques, Synthetic; Ciprofloxacin; Copper; DNA, Bacterial; Drug Evaluation, Preclinical; Fibroblasts; Fluoroquinolones; HEK293 Cells; Humans; Metronidazole; Mice; Microbial Sensitivity Tests; Molecular Targeted Therapy; Norfloxacin; Pseudomonas aeruginosa; Quinolones; Structure-Activity Relationship | 2015 |
Novel antibacterial active quinolone-fluoroquinolone conjugates and 2D-QSAR studies.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Quantitative Structure-Activity Relationship; Quinolones | 2015 |
Synthesis, antimycobacterial screening and ligand-based molecular docking studies on novel pyrrole derivatives bearing pyrazoline, isoxazole and phenyl thiourea moieties.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; Chemistry Techniques, Synthetic; Drug Evaluation, Preclinical; Enzyme Inhibitors; Escherichia coli; Humans; Isoxazoles; Ligands; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; Pyrroles; Staphylococcus aureus; Thiourea | 2016 |
Discovery of membrane active benzimidazole quinolones-based topoisomerase inhibitors as potential DNA-binding antimicrobial agents.
Topics: Anti-Bacterial Agents; Benzimidazoles; Binding Sites; DNA, Bacterial; Dose-Response Relationship, Drug; Drug Discovery; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Quinolones; Structure-Activity Relationship; Topoisomerase Inhibitors | 2016 |
Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities.
Topics: Anti-Infective Agents; Antimalarials; Antitubercular Agents; Bacteria; Bacterial Infections; Fungi; Humans; Malaria, Falciparum; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Mycoses; Plasmodium falciparum; Pyrazoles; Quinolines; Structure-Activity Relationship; Tuberculosis | 2016 |
Synthesis and molecular modeling of antimicrobial active fluoroquinolone-pyrazine conjugates with amino acid linkers.
Topics: Amino Acids; Anti-Bacterial Agents; Fluoroquinolones; Models, Molecular; Piperazines; Pseudomonas aeruginosa; Pyrazines; Quantitative Structure-Activity Relationship; Quinolines; Salmonella typhi; Staphylococcus aureus; Streptococcus pyogenes; Triazoles | 2016 |
Synthesis and biological evaluation of novel structural hybrids of benzofuroxan derivatives and fluoroquinolones.
Topics: Anti-Bacterial Agents; Bacteria; Benzoxazoles; Chemistry Techniques, Synthetic; Drug Design; Fluoroquinolones; Hemolysis; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Structure-Activity Relationship | 2016 |
Synthesis, biological evaluation and in silico molecular modeling of pyrrolyl benzohydrazide derivatives as enoyl ACP reductase inhibitors.
Topics: Anti-Bacterial Agents; Bacteria; Binding Sites; Cell Line, Tumor; Chemistry Techniques, Synthetic; Computer Simulation; Drug Design; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Protein Conformation; Pyrroles | 2017 |
Synthesis and biological screening of novel 2-morpholinoquinoline nucleus clubbed with 1,2,4-oxadiazole motifs.
Topics: Anti-Infective Agents; Bacteria; Bacterial Proteins; Catalytic Domain; Chemistry Techniques, Synthetic; Drug Evaluation, Preclinical; Fungi; Microbial Sensitivity Tests; Molecular Docking Simulation; Oxadiazoles; Quinolines; Structure-Activity Relationship | 2017 |
Synthesis, identification and in vitro biological evaluation of some novel quinoline incorporated 1,3-thiazinan-4-one derivatives.
Topics: Anti-Bacterial Agents; Antimalarials; Antitubercular Agents; Clostridium tetani; Gram-Negative Bacteria; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Plasmodium falciparum; Quinolines; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Thiazines | 2017 |
1,2,4-Triazole and 1,3,4-oxadiazole analogues: Synthesis, MO studies, in silico molecular docking studies, antimalarial as DHFR inhibitor and antimicrobial activities.
Topics: Anti-Infective Agents; Antimalarials; Folic Acid Antagonists; Molecular Docking Simulation; Oxadiazoles; Spectrum Analysis; Triazoles | 2017 |
Benzothiazole analogues: Synthesis, characterization, MO calculations with PM6 and DFT, in silico studies and in vitro antimalarial as DHFR inhibitors and antimicrobial activities.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Benzothiazoles; Cell Survival; Computer Simulation; Dose-Response Relationship, Drug; Folic Acid Antagonists; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Plasmodium falciparum; Quantum Theory; Schizosaccharomyces; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2017 |
Synthesis, antibacterial properties and 2D-QSAR studies of quinolone-triazole conjugates.
Topics: Anti-Bacterial Agents; Bacteria; Chemistry Techniques, Synthetic; Microbial Sensitivity Tests; Quantitative Structure-Activity Relationship; Quinolones; Triazoles | 2018 |
Design, synthesis and biological evaluation of novel aryldiketo acids with enhanced antibacterial activity against multidrug resistant bacterial strains.
Topics: Anti-Bacterial Agents; Bacteria; Catalytic Domain; Chemistry Techniques, Synthetic; Drug Design; Drug Resistance, Multiple; Humans; Hydrophobic and Hydrophilic Interactions; Keto Acids; Molecular Docking Simulation; Serum Albumin, Human; Structure-Activity Relationship | 2018 |
Discovery of novel arylethenesulfonyl fluorides as potential candidates against methicillin-resistant of Staphylococcus aureus (MRSA) for overcoming multidrug resistance of bacterial infections.
Topics: Bacterial Infections; Biofilms; Drug Resistance, Multiple; Electron Transport Chain Complex Proteins; Fluorides; Methicillin-Resistant Staphylococcus aureus; Molecular Docking Simulation; Oxidation-Reduction; Staphylococcal Infections; Sulfinic Acids; Sulfones | 2019 |
Antibacterial activity of indolyl-quinolinium derivatives and study their mode of action.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Indoles; Microbial Sensitivity Tests; Molecular Structure; Quinolinium Compounds; Structure-Activity Relationship | 2019 |
Design of Trp-Rich Dodecapeptides with Broad-Spectrum Antimicrobial Potency and Membrane-Disruptive Mechanism.
Topics: Anti-Infective Agents; Antimicrobial Cationic Peptides; Bacterial Outer Membrane; Drug Design; Escherichia coli; Humans; Microbial Sensitivity Tests; Oligopeptides; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Staphylococcus aureus; Tryptophan | 2019 |
Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents.
Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Positive Bacteria; HEK293 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Quaternary Ammonium Compounds; Quinolones; Structure-Activity Relationship | 2019 |
The synthesis and in vitro biological evaluation of novel fluorinated tetrahydrobenzo[j]phenanthridine-7,12-diones against Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Benzophenanthridines; Cell Line; Dose-Response Relationship, Drug; Humans; Hydrocarbons, Fluorinated; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2019 |
One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor.
Topics: Anti-Bacterial Agents; Antifungal Agents; Arylsulfonates; DNA Gyrase; Dose-Response Relationship, Drug; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Immunologic Factors; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Spiro Compounds; Structure-Activity Relationship; Topoisomerase Inhibitors | 2020 |
Synthesis, pharmacological profile and 2D-QSAR studies of curcumin-amino acid conjugates as potential drug candidates.
Topics: Amino Acids; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Carrageenan; Cell Proliferation; Curcumin; Dose-Response Relationship, Drug; Edema; Mice; Microbial Sensitivity Tests; Molecular Structure; Pain; Pseudomonas aeruginosa; Quantitative Structure-Activity Relationship; Rats; Salmonella typhi; Spleen; Staphylococcus aureus; Streptococcus pyogenes; Ulcer | 2020 |
Development of Bis-cyclic Imidazolidine-4-one Derivatives as Potent Antibacterial Agents.
Topics: Anti-Bacterial Agents; Biofilms; Cyclization; Drug Design; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Imidazolidines; Microbial Sensitivity Tests; Structure-Activity Relationship | 2020 |
Inhibition of the NorA efflux pump of S. aureus by (Z)-5-(4-Fluorobenzylidene)-Imidazolidines.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Dose-Response Relationship, Drug; Imidazolidines; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Multidrug Resistance-Associated Proteins; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship | 2021 |
Structure based design, synthesis, and biological evaluation of imidazole derivatives targeting dihydropteroate synthase enzyme.
Topics: Anti-Bacterial Agents; Dihydropteroate Synthase; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Imidazoles; Ligands; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin-Resistant Enterococci | 2021 |
Membrane active 7-thiazoxime quinolones as novel DNA binding agents to decrease the genes expression and exert potent anti-methicillin-resistant Staphylococcus aureus activity.
Topics: Anti-Bacterial Agents; Binding Sites; DNA, Bacterial; Dose-Response Relationship, Drug; Gene Expression Regulation, Bacterial; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Oximes; Quinolones; Structure-Activity Relationship | 2021 |
Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Cell Survival; Cell Wall; Disease Models, Animal; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; RAW 264.7 Cells; Salicylates; Skin Diseases; Staphylococcal Infections; Staphylococcus aureus; Stilbenes; Structure-Activity Relationship | 2021 |
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Proliferation; Cell Survival; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Nitric Oxide; Nitric Oxide Donors; Norfloxacin; Photochemical Processes; Staphylococcus aureus; Structure-Activity Relationship; Tumor Cells, Cultured | 2021 |
Tandem Repeat of a Short Human Chemerin-Derived Peptide and Its Nontoxic d-Lysine-Containing Enantiomer Display Broad-Spectrum Antimicrobial and Antitubercular Activities.
Topics: Animals; Antimicrobial Peptides; Antitubercular Agents; Cell Survival; Chemokines; Dose-Response Relationship, Drug; Erythrocytes; Humans; Lysine; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Pseudomonas Infections; Stereoisomerism; Structure-Activity Relationship; THP-1 Cells | 2021 |
An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a.
Topics: Allosteric Regulation; Allosteric Site; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Drug Design; Drug Resistance, Multiple; Gram-Negative Bacteria; Gram-Positive Bacteria; Hemolysis; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Docking Simulation; Naphthalimides; Oxidative Stress; Oximes; Penicillin-Binding Proteins; Structure-Activity Relationship | 2022 |
Potentiating the intracellular killing of Staphylococcus aureus by dihydroquinazoline analogues as NorA efflux pump inhibitor.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cell Survival; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Multidrug Resistance-Associated Proteins; Quinazolines; Staphylococcus aureus; Structure-Activity Relationship; THP-1 Cells | 2022 |
Design, synthesis, and biological evaluation of membrane-active honokiol derivatives as potent antibacterial agents.
Topics: Allyl Compounds; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Biphenyl Compounds; Lignans; Mice; Microbial Sensitivity Tests; Phenols | 2022 |
Pyrimidine-conjugated fluoroquinolones as new potential broad-spectrum antibacterial agents.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Norfloxacin; Pyrimidines | 2022 |
An unanticipated discovery of novel naphthalimidopropanediols as potential broad-spectrum antibacterial members.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Mammals; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus | 2022 |
In vitro activity of sparfloxacin and three other fluoroquinolones against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones; Staphylococcus aureus; Staphylococcus epidermidis | 1992 |
Comparative penetration of lomefloxacin and other quinolones into human phagocytes.
Topics: Analysis of Variance; Anti-Infective Agents; Ascitic Fluid; Ciprofloxacin; Fluoroquinolones; Humans; In Vitro Techniques; Macrophages; Neutrophils; Norfloxacin; Ofloxacin; Quinolones | 1992 |
Antibacterial activity of the new quinolone CI-960 (PD 127391) against clinical isolates at a major tertiary care center in Saudi Arabia.
Topics: Anti-Infective Agents; Ciprofloxacin; Enterobacter cloacae; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Hospitals, Urban; Klebsiella pneumoniae; Microbial Sensitivity Tests; Norfloxacin; Pseudomonas aeruginosa; Quinolones; Saudi Arabia | 1992 |
In vitro activity of sparfloxacin (CI-978), a new broad-spectrum fluoroquinolone.
Topics: Anti-Infective Agents; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Microbial Sensitivity Tests; Norfloxacin; Quinolones | 1992 |
[In vitro antimicrobial activities of new quinolone antibiotics against Mycoplasma pneumoniae].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Macrolides; Mycoplasma pneumoniae; Norfloxacin; Ofloxacin; Quinolones; Tetracyclines | 1992 |
In vitro evaluation of E-4695, a new fluoro-naphthyridine.
Topics: Anti-Bacterial Agents; Azetidines; Bacteria; Ciprofloxacin; Drug Evaluation, Preclinical; Enoxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones | 1992 |
[Influence of new quinolones on superoxide anion generation of polymorphonuclear leukocytes].
Topics: Ciprofloxacin; Enoxacin; Humans; In Vitro Techniques; Neutrophils; Norfloxacin; Ofloxacin; Superoxides | 1992 |
In vitro activity of CP-74667 compared with four other fluoroquinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Enoxacin; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones | 1992 |
In vitro and in vivo antibacterial activities of AM-1155, a new 6-fluoro-8-methoxy quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; DNA Topoisomerases, Type II; Drug Evaluation, Preclinical; Fluoroquinolones; Gatifloxacin; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Piperazines; Quinolones; Tissue Distribution | 1992 |
Comparative in vitro activities of a new quinolone, OPC-17116, possessing potent activity against gram-positive bacteria.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Topoisomerases, Type II; Fluoroquinolones; Gram-Positive Bacteria; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Piperazines; Quinolones; Staphylococcus aureus | 1992 |
Fluoroquinolone supersusceptibility mediated by outer membrane protein OprH overexpression in Pseudomonas aeruginosa: evidence for involvement of a nonporin pathway.
Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Cell Membrane; Chloramphenicol; Ciprofloxacin; Drug Resistance, Microbial; Fleroxacin; Gene Expression; Norfloxacin; Porins; Pseudomonas aeruginosa | 1992 |
Gemfibrozil enhances the listeriacidal effects of fluoroquinolone antibiotics in J774 macrophages.
Topics: Animals; Cell Line; Ciprofloxacin; Drug Synergism; Gemfibrozil; Listeria monocytogenes; Macrophages; Mice; Norfloxacin | 1992 |
[The clinical use of norfloxacin (Nolicin) and ciprofloxacin (Ciprinol)].
Topics: Bacterial Infections; Ciprofloxacin; Humans; Norfloxacin | 1992 |
Therapy of enteric fever.
Topics: Chloramphenicol Resistance; Ciprofloxacin; Dose-Response Relationship, Drug; Female; Humans; India; Male; Norfloxacin; Typhoid Fever | 1992 |
Determination of ofloxacin in human serum by high-performance liquid chromatography with column switching.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Humans; Hydrogen-Ion Concentration; Norfloxacin; Ofloxacin; Spectrophotometry, Ultraviolet | 1992 |
Inducible beta-lactamases in clinical isolates of non-aeruginosa Pseudomonas.
Topics: beta-Lactamases; Cefazolin; Chloromercuribenzoates; Ciprofloxacin; Clavulanic Acids; Cloxacillin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Edetic Acid; Humans; Hydrolysis; Imipenem; Isoelectric Point; Molecular Weight; Norfloxacin; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Spectrophotometry | 1992 |
Characterization of high-level quinolone resistance in Campylobacter jejuni.
Topics: Anti-Infective Agents; Campylobacter jejuni; Ciprofloxacin; DNA Topoisomerases, Type II; DNA, Superhelical; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Norfloxacin; Quinolones; Topoisomerase II Inhibitors | 1991 |
Fluorometric and high-performance liquid chromatographic measurement of quinolone uptake by human neutrophils.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fleroxacin; Fluorescence; Fluoroquinolones; Humans; Neutrophils; Norfloxacin; Ofloxacin; Quinolones | 1991 |
Antibacterial activity of a new tetracyclic quinolone, No. 5290, against norfloxacin- and ciprofloxacin-resistant strains of Staphylococcus aureus.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Mutation; Norfloxacin; Piperazines; Quinolones; Staphylococcus aureus; Thiazoles | 1991 |
Fluoroquinolone resistance in Campylobacter jejuni and Campylobacter coli isolated from human faeces in Switzerland.
Topics: Campylobacter coli; Campylobacter jejuni; Ciprofloxacin; Drug Resistance, Microbial; Feces; Humans; Norfloxacin; Switzerland | 1991 |
Uptake of 3H-norfloxacin in methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Ciprofloxacin; Culture Media; Drug Resistance, Microbial; Methicillin Resistance; Microbial Sensitivity Tests; Norfloxacin; Staphylococcus aureus | 1991 |
[Sensitivity of Pseudomonas mallei to fluoroquinolones and their efficacy in experimental glanders].
Topics: Animals; Ciprofloxacin; Cricetinae; Drug Resistance, Microbial; Glanders; Guinea Pigs; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pseudomonas | 1991 |
Development of resistance to quinolones in five patients with campylobacteriosis treated with norfloxacin or ciprofloxacin.
Topics: Adult; Campylobacter coli; Campylobacter Infections; Campylobacter jejuni; Ciprofloxacin; DNA, Bacterial; DNA, Ribosomal; Drug Resistance, Microbial; Female; Humans; Male; Nalidixic Acid; Norfloxacin; Restriction Mapping | 1991 |
The fluoroquinolones.
Topics: Bacterial Infections; Ciprofloxacin; Humans; Norfloxacin; Otitis Externa | 1991 |
Treatment of encrusted cystitis caused by Corynebacterium group D2 with norfloxacin, ciprofloxacin, and teicoplanin in an experimental model in rats.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Corynebacterium Infections; Cystitis; Female; Glycopeptides; Norfloxacin; Rats; Rats, Inbred Strains; Teicoplanin | 1991 |
Adverse reaction reporting of interaction between warfarin and fluoroquinolones.
Topics: Adult; Aged; Aged, 80 and over; Ciprofloxacin; Drug Interactions; Female; Humans; Male; Middle Aged; Norfloxacin; Product Surveillance, Postmarketing; United States; United States Food and Drug Administration; Warfarin | 1991 |
Mechanisms of fluoroquinolone resistance in Staphylococcus aureus.
Topics: Ampicillin; Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; Cloning, Molecular; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Humans; Membrane Proteins; Mutation; Norfloxacin; Nucleic Acid Hybridization; R Factors; Restriction Mapping; Staphylococcus aureus | 1991 |
In vitro susceptibility of Francisella tularensis to fluoroquinolones and treatment of tularemia with norfloxacin and ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Francisella tularensis; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pefloxacin; Tularemia | 1991 |
Streptococcus sanguis survival in K-Sol. Comparison of gentamicin and the fluoroquinolone antibiotics.
Topics: Anti-Infective Agents; Chondroitin Sulfates; Ciprofloxacin; Colony Count, Microbial; Gentamicins; HEPES; Norfloxacin; Ofloxacin; Streptococcus sanguis | 1991 |
The efficacy of topical ciprofloxacin and norfloxacin in the treatment of experimental Pseudomonas keratitis.
Topics: Administration, Topical; Animals; Ciprofloxacin; Colony Count, Microbial; Keratitis; Norfloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Tobramycin | 1991 |
Human serum enhances the postantibiotic effect of fluoroquinolones against Staphylococcus aureus.
Topics: Anti-Infective Agents; Blood Physiological Phenomena; Ciprofloxacin; Culture Media; Humans; Kinetics; Methicillin; Microbial Sensitivity Tests; Norfloxacin; Pefloxacin; Staphylococcus aureus | 1991 |
[Studies on pyridonecarboxylic acids as anti-bacterial agents. IX. Study on prodrugs of some pyridonecarboxylic acids].
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Escherichia coli Infections; Mice; Norfloxacin; Prodrugs | 1991 |
Oral antibiotic prophylaxis in patients with hematological diseases.
Topics: Ciprofloxacin; Humans; Norfloxacin; Sepsis; Staphylococcal Infections | 1991 |
Study of potential in vitro and in vivo genotoxicity in hepatocytes of quinolone antibiotics.
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; DNA; DNA Repair; Liver; Norfloxacin; Ofloxacin; Pefloxacin; Phosphorus Radioisotopes; Rats | 1991 |
Chlamydia trachomatis: in vitro susceptibility of genital and ocular isolates to some quinolones, amoxicillin and azithromycin.
Topics: Amoxicillin; Anti-Infective Agents; Azithromycin; Cervix Uteri; Chlamydia trachomatis; Ciprofloxacin; Conjunctiva; Drug Evaluation, Preclinical; Erythromycin; Female; Humans; Infant, Newborn; Male; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Urethra | 1990 |
Antimicrobial activity of intravenous quinolones on the intestinal microflora in dogs.
Topics: Animals; Anti-Infective Agents; Bacteroides fragilis; Ciprofloxacin; Colony Count, Microbial; Dogs; Enoxacin; Escherichia coli; Feces; Injections, Intravenous; Jejunum; Norfloxacin; Streptococcus | 1991 |
In vitro and in vivo antibacterial activities of E-4497, a new 3-amine-3-methyl-azetidinyl tricyclic fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Interactions; Fluoroquinolones; Magnesium; Male; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones | 1991 |
[Antibacterial activity of ciprofloxacin against fresh clinical isolates from superficial suppurative foci].
Topics: Amoxicillin; Bacteria; Cefaclor; Ciprofloxacin; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Suppuration | 1991 |
Fluoroquinolones protect the human lymphocyte CEM cell line from HIV-1-mediated cytotoxicity.
Topics: Acquired Immunodeficiency Syndrome; Cell Line; Cell Survival; Ciprofloxacin; Enoxacin; HIV-1; Humans; Lymphocytes; Norfloxacin; Ofloxacin | 1990 |
Influence of new quinolones on normal immune capabilities.
Topics: Animals; Anti-Infective Agents; Antibody Formation; Ciprofloxacin; Hypersensitivity, Delayed; Immunity, Cellular; Injections, Intramuscular; Male; Mice; Norfloxacin; Ofloxacin; Pefloxacin; Phagocytosis | 1990 |
Lomefloxacin-induced modification of the kinetics of growth of gram-negative bacteria and susceptibility to phagocytic killing by human neutrophils.
Topics: Anti-Infective Agents; Cell Division; Ciprofloxacin; Escherichia coli; Fluoroquinolones; Gram-Negative Bacteria; Humans; Neutrophils; Norfloxacin; Nucleic Acids; Phagocytosis; Pseudomonas aeruginosa; Quinolones; Tritium | 1990 |
Quinolone pharmacokinetics and metabolism.
Topics: Administration, Oral; Anti-Infective Agents; Biological Availability; Biotransformation; Ciprofloxacin; Enoxacin; Fleroxacin; Half-Life; Humans; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Pefloxacin | 1990 |
In vitro activity of fleroxacin against aerobic gram-positive bacteria including Corynebacterium jeikeium.
Topics: Bacteria, Aerobic; Ciprofloxacin; Corynebacterium; Fleroxacin; Gram-Positive Bacteria; Microbial Sensitivity Tests; Norfloxacin; Streptococcus pyogenes | 1990 |
In-vitro activity of azithromycin, erythromycin, ciprofloxacin and norfloxacin against Neisseria gonorrhoeae, Haemophilus ducreyi, and Chlamydia trachomatis.
Topics: Azithromycin; Chlamydia trachomatis; Ciprofloxacin; Erythromycin; Haemophilus ducreyi; Neisseria gonorrhoeae; Norfloxacin | 1990 |
Possible interaction of fluoroquinolones with the benzodiazepine-GABAA-receptor complex.
Topics: Adult; Animals; Brain Chemistry; Ciprofloxacin; Double-Blind Method; Electroencephalography; Female; Flunitrazepam; Humans; In Vitro Techniques; Male; Middle Aged; Norfloxacin; Ofloxacin; Quinolones; Radioligand Assay; Random Allocation; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Membranes | 1990 |
Mechanism of action of lomefloxacin.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; DNA Topoisomerases, Type II; DNA, Bacterial; DNA, Superhelical; Fluoroquinolones; Kinetics; Microbial Sensitivity Tests; Norfloxacin; Quinolones; Rec A Recombinases | 1990 |
Quinolones in collagen shields to treat aminoglycoside-resistant pseudomonal keratitis.
Topics: Animals; Ciprofloxacin; Collagen; Colony Count, Microbial; Cornea; Drug Resistance, Microbial; Eye Infections, Bacterial; Keratitis; Norfloxacin; Pharmaceutical Vehicles; Pseudomonas aeruginosa; Quinolones; Rabbits; Tobramycin | 1990 |
Pharmacokinetic determination of relative potency of quinolone inhibition of caffeine disposition.
Topics: Caffeine; Ciprofloxacin; Drug Interactions; Enoxacin; Humans; Male; Models, Biological; Norfloxacin; Ofloxacin; Pipemidic Acid; Quinolones | 1990 |
In vitro emergence of quinolone-resistant mutants of Escherichia coli, Enterobacter cloacae, and Serratia marcescens.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enterobacter; Enterobacteriaceae; Escherichia coli; Mutation; Norfloxacin; Serratia marcescens | 1990 |
[In vitro activity of 4 fluoroquinolones against Klebsiella pneumoniae. Distribution according to phenotype resistance to aminoglycosides or beta-lactams].
Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; In Vitro Techniques; Klebsiella pneumoniae; Norfloxacin; Ofloxacin; Pefloxacin; Phenotype | 1990 |
The influence of quinolones on the faecal flora.
Topics: Anti-Infective Agents; Ciprofloxacin; Enterobacteriaceae; Feces; Humans; Intestines; Norfloxacin; Ofloxacin; Pefloxacin | 1990 |
The pharmacokinetics of oral quinolones (norfloxacin, ciprofloxacin, ofloxacin).
Topics: Administration, Oral; Ciprofloxacin; Half-Life; Humans; Intestinal Absorption; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Time Factors | 1990 |
Fluoroquinolone drug interactions.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Humans; Norfloxacin | 1990 |
In vitro susceptibility of selected veterinary bacterial pathogens to ciprofloxacin, enrofloxacin and norfloxacin.
Topics: Actinobacillus; Actinomyces; Anti-Infective Agents; Ciprofloxacin; Corynebacterium; Enrofloxacin; Erysipelothrix; Fluoroquinolones; Haemophilus; In Vitro Techniques; Microbial Sensitivity Tests; Norfloxacin; Pasteurella; Quinolones; Rhodococcus; Streptococcus | 1990 |
In vitro effect of fluoroquinolones on theophylline metabolism in human liver microsomes.
Topics: Biotransformation; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Interactions; Enoxacin; Humans; Hydroxylation; Microsomes, Liver; Norfloxacin; Theophylline; Uric Acid; Xanthines | 1990 |
[Therapeutic drug monitoring of fluoroquinolone].
Topics: Anti-Infective Agents; Bile; Biological Assay; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones; Sputum | 1990 |
[Antibacterial activity of norfloxacin, ofloxacin and ciprofloxacin according to resistance phenotypes to nalidixic acid and pefloxacin].
Topics: Ciprofloxacin; Drug Resistance, Microbial; Gram-Negative Aerobic Bacteria; In Vitro Techniques; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; Phenotype; Staphylococcus aureus | 1990 |
Susceptibility pattern of bacterial isolates to lomefloxacin.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Nalidixic Acid; Norfloxacin; Quinolones | 1990 |
DNA breakdown by the 4-quinolones and its significance.
Topics: Ciprofloxacin; DNA, Bacterial; Escherichia coli; Nalidixic Acid; Norfloxacin; Rifampin; SOS Response, Genetics; Species Specificity; Time Factors | 1990 |
The in vitro activity of norfloxacin, ofloxacin and ciprofloxacin and other antibiotics in current use against Neisseria gonorrhoeae.
Topics: Ampicillin; Ampicillin Resistance; Ciprofloxacin; Doxycycline; Drug Resistance, Microbial; Gonorrhea; Humans; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Penicillin Resistance | 1989 |
Comparative in vitro activity of lomefloxacin, a new difluoroquinolone.
Topics: Anti-Infective Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Ceftazidime; Ciprofloxacin; Drug Evaluation, Preclinical; Fluoroquinolones; Gentamicins; Microbial Sensitivity Tests; Norfloxacin; Quinolones | 1989 |
Synthesis of novel 5-fluoro analogues of norfloxacin and ciprofloxacin.
Topics: Animals; Chemical Phenomena; Chemistry; Ciprofloxacin; Enterobacter; Enterococcus faecalis; Escherichia coli; Escherichia coli Infections; Klebsiella pneumoniae; Magnetic Resonance Spectroscopy; Mice; Microbial Sensitivity Tests; Molecular Structure; Norfloxacin; Pseudomonas aeruginosa; Serratia marcescens; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship | 1989 |
Antimicrobial activity and interaction of pefloxacin and its principal metabolites. Collaborative Antimicrobial Susceptibility Testing Group.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Interactions; Drug Therapy, Combination; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Norfloxacin; Pefloxacin; Staphylococcus; Streptococcus | 1989 |
Studies on the emergence of resistance to lomefloxacin in vitro.
Topics: Anti-Infective Agents; Ciprofloxacin; Cystitis; Drug Resistance, Microbial; Escherichia coli; Fluoroquinolones; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Biological; Norfloxacin; Quinolones | 1989 |
Quinolone resistance. Susceptibility data from a 300-bed community hospital.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Norfloxacin; Pseudomonas aeruginosa | 1989 |
[Activity of 5 fluoroquinolones on hospital Gram-negative bacilli with different sensitivities to pefloxacin].
Topics: Anti-Infective Agents; Ciprofloxacin; Citrobacter; Drug Resistance, Microbial; Enoxacin; Escherichia coli; Fleroxacin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pefloxacin; Pseudomonas aeruginosa; Serratia marcescens | 1989 |
Evaluation of four newer antimicrobial agents in the Avantage susceptibility test system.
Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria; Cefotetan; Ciprofloxacin; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Evaluation Studies as Topic; Microbial Sensitivity Tests; Norfloxacin | 1989 |
In vitro and in vivo antibacterial activities of KB-5246, a new tetracyclic quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Male; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Phenalenes; Quinolones | 1989 |
Increasing incidence of Corynebacterium group D2 strains resistant to norfloxacin and ciprofloxacin.
Topics: Ciprofloxacin; Corynebacterium; Corynebacterium Infections; Drug Resistance, Microbial; Humans; Norfloxacin; Species Specificity | 1989 |
[Fluoroquinolones--antibacterial activity, pharmacokinetics and indications for a new group of chemotherapeutic drugs].
Topics: Adult; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Dose-Response Relationship, Drug; Enoxacin; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Norfloxacin; Ofloxacin | 1989 |
Mechanisms of quinolone resistance in Escherichia coli: characterization of nfxB and cfxB, two mutant resistance loci decreasing norfloxacin accumulation.
Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Ciprofloxacin; Conjugation, Genetic; Culture Media; Drug Resistance, Microbial; Energy Metabolism; Escherichia coli; Hydrogen-Ion Concentration; Magnesium; Mutation; Norfloxacin; Spheroplasts; Transduction, Genetic | 1989 |
In vivo activity of ciprofloxacin, ofloxacin, norfloxacin and pipemidic acid against Escherichia coli infections in mice.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Escherichia coli Infections; Female; Mice; Microbial Sensitivity Tests; Neutropenia; Norfloxacin; Ofloxacin; Pipemidic Acid; Time Factors; Urinary Tract Infections; Uterus | 1989 |
Increasing rates of in vitro resistance to ciprofloxacin and norfloxacin in isolates from urine specimens.
Topics: Bacteria; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Humans; Norfloxacin | 1989 |
[In vitro determination of the sensitivity of mycobacteria to fluoroquinolones].
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Mycobacterium; Norfloxacin; Ofloxacin; Pefloxacin | 1989 |
In vitro and in vivo antibacterial activities of AT-4140, a new broad-spectrum quinolone.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Enoxacin; Fluoroquinolones; Lung Diseases; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Skin Diseases, Infectious; Urinary Tract Infections | 1989 |
In-vitro synergistic activity between ethambutol and fluorinated quinolones against Mycobacterium avium complex.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Drug Synergism; Ethambutol; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Norfloxacin; Ofloxacin | 1989 |
The role of quinolones in staphylococcal infection.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Humans; Norfloxacin; Ofloxacin; Pefloxacin; Staphylococcal Infections | 1989 |
Comparative in vitro activity of ciprofloxacin against aerobic and anaerobic bacteria from clinical isolates.
Topics: Anti-Bacterial Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Nalidixic Acid; Norfloxacin; Pseudomonas; Topoisomerase II Inhibitors | 1987 |
[Gyrase inhibitors modify metabolising processes in the liver].
Topics: Caffeine; Ciprofloxacin; DNA Topoisomerases, Type II; Enoxacin; Humans; Liver; Male; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Topoisomerase II Inhibitors | 1987 |
Modifications of DNA-gyrase and of permeability in a norfloxacin-resistant clinical isolate of Providencia stuartii.
Topics: Bacterial Outer Membrane Proteins; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; DNA Topoisomerases, Type II; DNA, Superhelical; Drug Resistance, Microbial; Electrophoresis, Polyacrylamide Gel; Mutation; Norfloxacin; Proteus; Providencia; Topoisomerase II Inhibitors | 1987 |
Activity of fluoroquinolone antibiotics against Plasmodium falciparum in vitro.
Topics: Aminocoumarins; Animals; Anti-Infective Agents; Chloroquine; Ciprofloxacin; Coumarins; Drug Interactions; Drug Resistance; Enoxacin; Fluoroquinolones; Nalidixic Acid; Norfloxacin; Novobiocin; Ofloxacin; Oxolinic Acid; Pefloxacin; Plasmodium falciparum; Tetracycline; Topoisomerase II Inhibitors | 1988 |
Clinical use of the quinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Diarrhea; Enoxacin; Gastrointestinal Diseases; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Osteomyelitis; Oxazines; Pefloxacin; Quinolines; Respiratory Tract Infections; Sexually Transmitted Diseases; Surgical Wound Infection; Urinary Tract Infections | 1987 |
Susceptibility of Bordetella pertussis to five quinolone antimicrobic drugs.
Topics: Anti-Bacterial Agents; Bordetella pertussis; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Whooping Cough | 1987 |
Ciprofloxacin and norfloxacin--potent oral antiinfectives.
Topics: Administration, Oral; Bacterial Infections; Ciprofloxacin; Humans; Norfloxacin | 1989 |
Influence of faeces on the activity of antimicrobial agents used for decontamination of the alimentary canal.
Topics: Anti-Bacterial Agents; Aztreonam; Ciprofloxacin; Colistin; Digestive System; Dose-Response Relationship, Drug; Feces; Humans; Nalidixic Acid; Neomycin; Norfloxacin; Pipemidic Acid; Quinolines; Tobramycin | 1985 |
Evaluation of the in vitro bactericidal action of ciprofloxacin on cells of Escherichia coli in the logarithmic and stationary phases of growth.
Topics: Chloramphenicol; Ciprofloxacin; Drug Interactions; Escherichia coli; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Norfloxacin; Quinolines; Time Factors | 1985 |
In vitro activities of ciprofloxacin, ofloxacin, norfloxacin and rosoxacin compared with cinoxacin and trimethoprim.
Topics: 4-Quinolones; Acinetobacter; Anti-Infective Agents; Anti-Infective Agents, Urinary; Cinoxacin; Ciprofloxacin; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines; Quinolones; Trimethoprim | 1985 |
Effect of ciprofloxacin on phagocytosis.
Topics: Chemotaxis, Leukocyte; Ciprofloxacin; Humans; Luminescent Measurements; Neutrophils; Norfloxacin; Ofloxacin; Oxazines; Phagocytosis; Providencia; Quinolines; Staphylococcus aureus | 1985 |
The comparative in-vitro activity of norfloxacin, ciprofloxacin, enoxacin and nalidixic acid against 423 strains of gram-negative rods and staphylococci isolated from infected hospitalised patients.
Topics: Acinetobacter; Bacteria; Bacterial Infections; Ciprofloxacin; Citrobacter; Drug Resistance, Microbial; Enoxacin; Enterobacteriaceae; Escherichia coli; Humans; Klebsiella; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Pseudomonas aeruginosa; Quinolines; Serratia; Staphylococcus | 1986 |
The in-vitro comparative activity of quinolones against bacteria from urinary tract infections in general practice.
Topics: Anti-Infective Agents, Urinary; Bacteria; Ciprofloxacin; Enterococcus faecalis; Escherichia coli; Humans; Microbial Sensitivity Tests; Norfloxacin; Pefloxacin; Pseudomonas; Quinolines; Staphylococcus; Urinary Tract Infections | 1986 |
[New oral quinolone compounds in chronic bronchitis].
Topics: Administration, Oral; Anti-Bacterial Agents; Bacterial Infections; Bronchitis; Chronic Disease; Ciprofloxacin; Dose-Response Relationship, Drug; Enoxacin; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Male; Middle Aged; Naphthyridines; Neisseria; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pneumococcal Infections; Pseudomonas Infections; Quinolines; Streptococcus pneumoniae | 1986 |
New 4-quinolones in the treatment of urinary tract infections.
Topics: Anti-Infective Agents, Urinary; Ciprofloxacin; Drug Combinations; Humans; Male; Norfloxacin; Pefloxacin; Prostatitis; Pseudomonas Infections; Quinolines; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Bladder, Neurogenic; Urinary Tract Infections | 1986 |
Quinolones and colonization resistance in human volunteers.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Digestive System; Feces; Female; Humans; Male; Nalidixic Acid; Norfloxacin; Pefloxacin; Quinolines | 1986 |
Quantitative determination of ofloxacin, ciprofloxacin, norfloxacin and pefloxacin in serum by high pressure liquid chromatography.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Humans; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Spectrophotometry, Ultraviolet | 1986 |
In vitro activity of the aryl-fluoroquinolones A-56619 and A-56620 and evaluation of disk susceptibility tests.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Microbial Sensitivity Tests; Norfloxacin; Piperazines; Quinolines; Staphylococcus; Streptococcus | 1986 |
Activity of ciprofloxacin against resistant clinical isolates.
Topics: Bacteria; Bacterial Infections; Cefotaxime; Ceftazidime; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Humans; Microbial Sensitivity Tests; Norfloxacin; Quinolines | 1986 |
Comparative in vitro activities of ciprofloxacin, enoxacin, norfloxacin, ofloxacin and pefloxacin against Bacteroides fragilis and Clostridium difficile.
Topics: Anti-Bacterial Agents; Bacteroides fragilis; Ciprofloxacin; Clostridium; Enoxacin; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1986 |
The action of quinolone carboxylic acids on Chlamydia trachomatis in vitro.
Topics: Animals; Carboxylic Acids; Cells, Cultured; Chlamydia trachomatis; Ciprofloxacin; Enoxacin; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1986 |
The clinical use of quinolones.
Topics: Ciprofloxacin; Escherichia coli; Feces; Female; Genital Diseases, Female; Genital Diseases, Male; Humans; Kinetics; Male; Micrococcus; Nalidixic Acid; Norfloxacin; Quinolines; Respiratory Tract Infections; Time Factors; Urologic Diseases | 1986 |
The comparative in-vitro activity of pefloxacin.
Topics: Acinetobacter; Aeromonas; Aminoglycosides; Anti-Bacterial Agents; Bacteria; Bacteroides; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Gardnerella vaginalis; Haemophilus influenzae; Lactams; Neisseria gonorrhoeae; Norfloxacin; Pefloxacin; Pseudomonas aeruginosa; Quinolines; Streptococcus | 1986 |
In-vitro activity of newer quinolones against aerobic bacteria.
Topics: Anti-Bacterial Agents; Bacteria, Aerobic; Calcium; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Magnesium Sulfate; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pseudomonas; Quinolines; Sulfates; Zinc; Zinc Sulfate | 1986 |
Comparative efficacy of pefloxacin and six other antimicrobial agents on Staphylococcus aureus experimental abscesses.
Topics: Abscess; Administration, Oral; Animals; Anti-Bacterial Agents; Cephalothin; Ciprofloxacin; Injections, Subcutaneous; Methicillin; Mice; Norfloxacin; Pefloxacin; Penicillin Resistance; Peptides; Quinolines; Staphylococcal Infections; Staphylococcus aureus; Thigh; Vancomycin; Virginiamycin | 1986 |
In vitro comparison of A-56619, A-56620, amifloxacin, ciprofloxacin, enoxacin, norfloxacin, and ofloxacin against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Methicillin; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Penicillin Resistance; Piperazines; Quinolines; Staphylococcus aureus | 1986 |
Comparative in vitro activity of seven quinolones against 100 clinical isolates of Clostridium difficile.
Topics: Anti-Bacterial Agents; Child; Ciprofloxacin; Clostridium; Enoxacin; Fluoroquinolones; Humans; Infant, Newborn; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1986 |
The comparative in vitro activity of twelve 4-quinolone antimicrobials against enteric pathogens.
Topics: 4-Quinolones; Aeromonas; Anti-Bacterial Agents; Anti-Infective Agents; Campylobacter fetus; Cinoxacin; Ciprofloxacin; Diarrhea; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Intestines; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Salmonella; Shigella; Vibrio cholerae; Vibrio parahaemolyticus; Yersinia enterocolitica | 1985 |
The comparative activity of twelve 4-quinolone antimicrobials against Haemophilus influenzae and Streptococcus pneumoniae.
Topics: 4-Quinolones; Anti-Infective Agents; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Streptococcus pneumoniae | 1985 |
Comparative in vitro studies with 4-quinolone antimicrobials.
Topics: 4-Quinolones; Anti-Infective Agents; Bacteria; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones | 1985 |
Comparative in vitro activity of ciprofloxacin and five other quinoline derivatives against gram-negative isolates.
Topics: Bacteriuria; Cinoxacin; Ciprofloxacin; Gram-Negative Bacteria; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Oxolinic Acid; Pipemidic Acid; Quinolines | 1985 |
Influence of pH and human urine on the antibacterial activity of ciprofloxacin, norfloxacin and ofloxacin.
Topics: Ciprofloxacin; Escherichia coli; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus; Urine | 1985 |
Assessment of the in vitro and in vivo activity of ciprofloxacin measured against current standards of therapy.
Topics: Ampicillin; Animals; Azlocillin; Blood; Ciprofloxacin; Escherichia coli; Humans; In Vitro Techniques; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines; Sisomicin; Tobramycin | 1985 |
Comparative antimicrobial activity of enoxacin, ciprofloxacin, amifloxacin, norfloxacin and ofloxacin against 177 bacterial isolates.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines | 1986 |
In vitro evaluation of A-56619 and A-56620, two new quinolones.
Topics: Anti-Bacterial Agents; Bacteria; Bacteria, Anaerobic; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Piperazines; Quinolines | 1986 |
In vitro and in vivo antibacterial activity of AM-833, a new quinolone derivative.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Fleroxacin; Male; Mice; Mice, Inbred ICR; Norfloxacin; Ofloxacin; Oxazines; Pneumonia; Quinolines; Urinary Tract Infections | 1986 |
Determination of ciprofloxacine, norfloxacine, and ofloxacine by high performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Humans; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1986 |
In vitro studies of S-25930 and S-25932, two new 4-quinolones.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Edetic Acid; Enterobacteriaceae; Gram-Positive Bacteria; Humans; Kinetics; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Quinolines; Quinolizines | 1986 |
[In vitro activity of seven gyrase inhibitors of a group of heterocyclic carbonic acids against nonfermenting gram negative rods (nonfermenters)].
Topics: Anti-Bacterial Agents; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Gram-Negative Aerobic Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Pseudomonas aeruginosa; Quinolines; Topoisomerase II Inhibitors | 1985 |
[Biotransformation of selected gyrase inhibitors].
Topics: Anti-Infective Agents; Biotransformation; Ciprofloxacin; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1986 |
Clinical uses of nalidixic acid analogues: the fluoroquinolones.
Topics: Administration, Oral; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Drug Evaluation; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Humans; Male; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Topoisomerase II Inhibitors | 1986 |
Inhibition of DNA gyrase by optically active ofloxacin.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Electrophoresis, Agar Gel; Escherichia coli; Micrococcus; Norfloxacin; Ofloxacin; Oxazines; Topoisomerase II Inhibitors | 1987 |
[Resistance against new gyrase inhibitors--1985/86].
Topics: Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Topoisomerase II Inhibitors | 1987 |
Association between early inhibition of DNA synthesis and the MICs and MBCs of carboxyquinolone antimicrobial agents for wild-type and mutant [gyrA nfxB(ompF) acrA] Escherichia coli K-12.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Mutation; Norfloxacin | 1988 |
Endogenous active efflux of norfloxacin in susceptible Escherichia coli.
Topics: Anti-Infective Agents; Biological Transport, Active; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Enoxacin; Escherichia coli; Kinetics; Norfloxacin; Ofloxacin; Spheroplasts | 1988 |
Penetrability of ofloxacin into cultured epithelial cells and macrophages.
Topics: Animals; Cell Membrane Permeability; Cells, Cultured; Ciprofloxacin; Epithelium; HeLa Cells; Macrophages; Male; Norfloxacin; Ofloxacin; Salmonella typhimurium; Shigella | 1988 |
Inhibition of plasmid conjugation by some recently synthetized 4-quinolone compounds.
Topics: Anti-Infective Agents; Chemical Phenomena; Chemistry; Ciprofloxacin; Conjugation, Genetic; Escherichia coli; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; R Factors | 1988 |
In vitro evaluation of A-56619 (difloxacin) and A-56620: new aryl-fluoroquinolones.
Topics: Anti-Infective Agents; Aztreonam; Bacteria; Cefotaxime; Ciprofloxacin; Drug Combinations; Enterobacteriaceae; Escherichia coli; Fluoroquinolones; Gentamicins; Haemophilus influenzae; Half-Life; Humans; Imipenem; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Penicillins; Piperacillin; Piperazines; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus; Streptococcus; Thienamycins | 1986 |
In vitro activity of aryl fluoroquinolones, Abbott 56619 and Abbott 56620, compared to ciprofloxacin, norfloxacin and beta-lactams versus multidrug-resistant Enterobacteriaceae and Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Microbial Sensitivity Tests; Norfloxacin; Pseudomonas aeruginosa | 1986 |
[In vitro activity of new quinolones against nonfermenters and references to sensitivity tests].
Topics: Acinetobacter; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Gram-Negative Bacteria; Immunodiffusion; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Pseudomonas | 1986 |
Activity of ciprofloxacin against multiply resistant strains of Pseudomonas aeruginosa, Staphylococcus epidermidis, and group JK corynebacteria.
Topics: Actinomycetales; Cefotaxime; Ciprofloxacin; Gentamicins; Humans; Methicillin; Mezlocillin; Microbial Sensitivity Tests; Norfloxacin; Penicillin Resistance; Pseudomonas aeruginosa; Staphylococcus epidermidis; Ticarcillin; Vancomycin | 1986 |
In vitro activity of A-56619 (difloxacin), A-56620, and other new quinolone antimicrobial agents against genital pathogens.
Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Ciprofloxacin; Female; Fluoroquinolones; Gardnerella vaginalis; Genitalia; Haemophilus; Haemophilus ducreyi; Humans; Male; Microbial Sensitivity Tests; Mycoplasma; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Oxazines; Ureaplasma | 1986 |
In vitro activity of RO 23-6240 (AM-833): a new fluoroquinolone.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Fleroxacin; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
In vitro activity of the new 4-quinolone compound Ro 23-6240.
Topics: Anti-Bacterial Agents; Bacteria; Bacteroides fragilis; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Fleroxacin; Gentamicins; Haemophilus influenzae; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Pefloxacin; Pseudomonas aeruginosa; Staphylococcus aureus | 1987 |
Comparative in-vitro activity of five fluoroquinolones against mycobacteria.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Enoxacin; Mycobacterium; Mycobacterium avium; Mycobacterium bovis; Mycobacterium tuberculosis; Naphthyridines; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
In-vitro activity of six fluorinated quinolones against Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1987 |
[In vitro antibacterial activity of new derivatives of pyridonecarboxylic acid, norfloxacin, ofloxacin, enoxacin and ciprofloxacin, against Vibrio cholerae O-1].
Topics: Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Vibrio cholerae | 1987 |
[In vitro and in vivo activities of norfloxacin, ofloxacin and ciprofloxacin against various mycobacteria].
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Female; Mice; Mycobacterium; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines | 1987 |
[Comparative in vitro activity of 10 new 4-quinolones against enteropathogenic bacteria].
Topics: Anti-Bacterial Agents; Campylobacter fetus; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Salmonella; Shigella; Vibrio cholerae; Yersinia enterocolitica | 1987 |
Comparative in vitro activity of RO 23-6240 (fleroxacin), a new 4-quinolone derivative.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Enterobacteriaceae; Enterococcus faecalis; Fleroxacin; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Staphylococcus | 1987 |
Membrane permeability of Pseudomonas aeruginosa to 4-quinolones.
Topics: Anti-Bacterial Agents; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Drug Resistance, Microbial; Escherichia coli; Humans; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Polymyxin B; Pseudomonas aeruginosa; Quinolines | 1987 |
A comparison of the in-vitro activity of seventeen antibiotics against Streptococcus faecalis.
Topics: Ampicillin; Anti-Bacterial Agents; Ciprofloxacin; Enterococcus faecalis; Mezlocillin; Microbial Sensitivity Tests; Norfloxacin | 1987 |
Comparative in-vitro activity of Ro 23-6240, a new trifluorinated quinolone.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines | 1987 |
Resistance occurring after fluoroquinolone therapy of experimental Pseudomonas aeruginosa peritonitis.
Topics: Animals; Ciprofloxacin; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Norfloxacin; Pefloxacin; Peritonitis; Pseudomonas aeruginosa; Pseudomonas Infections | 1987 |
In vitro activity of five new quinolones against cultivable mycobacteria.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
In vitro activity of four fluoroquinolones against eighty-six isolates of mycobacteria.
Topics: Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Development of resistance in Pseudomonas aeruginosa to imipenem, norfloxacin, and ciprofloxacin during therapy: proof provided by typing with a DNA probe.
Topics: Ciprofloxacin; DNA, Bacterial; Drug Resistance, Microbial; Imipenem; Norfloxacin; Plasmids; Pseudomonas aeruginosa; Thienamycins | 1988 |
Enhancement of interleukin 2 production by quinolone-treated human mononuclear leukocytes.
Topics: Anti-Infective Agents; Ciprofloxacin; Humans; In Vitro Techniques; Interleukin-2; Kinetics; Leukocytes, Mononuclear; Lymphocyte Activation; Mitomycin; Mitomycins; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Receptors, Immunologic; Receptors, Interleukin-2 | 1988 |
Comparative in vitro activity of the new quinolone fleroxacin (RO 23-6240).
Topics: Amikacin; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteria; Cefaclor; Ceftazidime; Cefuroxime; Ciprofloxacin; Clavulanic Acids; Corynebacterium; Drug Combinations; Drug Resistance, Microbial; Fleroxacin; Norfloxacin; Pefloxacin; Piperacillin; Staphylococcus; Vancomycin | 1988 |
In vitro activity of three fluoroquinolones against enterococci and Pseudomonas aeruginosa: modified categorization system for discrepant broth dilution and agar disk diffusion test results.
Topics: Ciprofloxacin; Drug Evaluation, Preclinical; Immunodiffusion; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Streptococcus | 1988 |
The response of Streptococcus faecalis to ciprofloxacin, norfloxacin and enoxacin.
Topics: Anti-Infective Agents, Urinary; Ciprofloxacin; Culture Media; Drug Resistance, Microbial; Enoxacin; Enterococcus faecalis; Humans; Naphthyridines; Nephelometry and Turbidimetry; Norfloxacin; Urinary Bladder | 1988 |
Activity of E-3846, a new fluoroquinolone, in vitro and in experimental cystitis and pyelonephritis in rats.
Topics: Animals; Anti-Infective Agents; Anti-Infective Agents, Urinary; Bacteria; Chemical Phenomena; Chemistry; Ciprofloxacin; Cystitis; Disease Models, Animal; Enterobacteriaceae; Escherichia coli Infections; Female; Fluoroquinolones; Hydrogen-Ion Concentration; Klebsiella Infections; Norfloxacin; Proteus Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Pyelonephritis; Quinolines; Quinolones; Rats; Rats, Inbred Strains; Staphylococcus; Streptococcal Infections; Streptococcus | 1988 |
Alterations in outer membrane proteins of Pseudomonas aeruginosa associated with selective resistance to quinolones.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Cell Membrane; Cephalosporins; Ciprofloxacin; Drug Resistance, Microbial; Electrophoresis, Polyacrylamide Gel; Humans; Norfloxacin; Penicillins; Pseudomonas aeruginosa | 1988 |
[In vitro antibacterial activity of piperacillin/quinolone combinations].
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Synergism; Escherichia coli; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Piperacillin; Pseudomonas aeruginosa; Serratia marcescens | 1988 |
[Comparative bactericidal kinetics of ciprofloxacin, ofloxacin and pefloxacin alone and in combination against strains of group D Streptococcus].
Topics: Amoxicillin; Anti-Bacterial Agents; Ciprofloxacin; Drug Synergism; Enterococcus faecalis; Fosfomycin; Microbial Sensitivity Tests; Netilmicin; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Penicillin G; Vancomycin | 1988 |
[Post-antibiotic effect of ciprofloxacin alone and in combination on Streptococcus faecalis].
Topics: Ciprofloxacin; Drug Synergism; Enterococcus faecalis; Fosfomycin; Microbial Sensitivity Tests; Netilmicin; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Vancomycin | 1988 |
[Corynebacterium group D2. Clinical study, biochemical identification and antibiotic sensitivity].
Topics: Anti-Bacterial Agents; Ciprofloxacin; Corynebacterium; Corynebacterium Infections; Drug Resistance, Microbial; Enoxacin; Female; Humans; Male; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Peptides, Cyclic; Pipemidic Acid; Rifampin; Tetracycline; Tetracycline Resistance; Urinary Tract Infections; Vancomycin; Virginiamycin | 1988 |
[Sensitivity of 7 mycobacterial species to new quinolones].
Topics: Amikacin; Anti-Bacterial Agents; Ciprofloxacin; Drug Combinations; Drug Synergism; Erythromycin; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Sulfamethoxazole; Thienamycins; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
[In vitro activity of new quinolones against Mycoplasma pathogenic to humans].
Topics: 4-Quinolones; Anti-Bacterial Agents; Ciprofloxacin; Enoxacin; Humans; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma pneumoniae; Mycoplasmataceae; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Quinolones; Ureaplasma | 1988 |
[Trends of fluoroquinolone-resistant strains isolated from clinical materials].
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Humans; Norfloxacin; Ofloxacin | 1988 |
Development of resistance to nalidixic acid and the fluoroquinolones after the introduction of norfloxacin and ofloxacin.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Enterobacteriaceae; Enterococcus faecalis; Humans; Nalidixic Acid; Norfloxacin; Ofloxacin; Pseudomonas aeruginosa; Staphylococcus aureus | 1988 |
Comparative activities of norfloxacin and fleroxacin in experimental infections due to Salmonella typhimurium and Escherichia coli.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Escherichia coli Infections; Female; Fleroxacin; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Norfloxacin; Salmonella Infections, Animal; Salmonella typhimurium | 1988 |
In-vitro activity of fleroxacin compared with three other quinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fleroxacin; Microbial Sensitivity Tests; Norfloxacin; Pefloxacin | 1988 |
Fleroxacin: in-vitro activity worldwide against 20,807 clinical isolates and comparison to ciprofloxacin and norfloxacin.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Fleroxacin; Microbial Sensitivity Tests; Norfloxacin | 1988 |
Effect of method, medium, pH and inoculum on the in-vitro antibacterial activities of fleroxacin and norfloxacin.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Culture Media; Fleroxacin; Hydrogen-Ion Concentration; Methods; Norfloxacin | 1988 |
Correlation of in vitro activities of the fluoroquinolones to their in vivo efficacies.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1988 |
In vitro activities of ofloxacin and four other new quinoline-carboxylic acids against Chlamydia trachomatis.
Topics: Anti-Infective Agents; Chlamydia trachomatis; Ciprofloxacin; Doxycycline; Fleroxacin; Fluoroquinolones; Minocycline; Norfloxacin; Ofloxacin; Quinolones | 1988 |
Comparative evaluation of recently developed quinolone compounds--with a note on the frequency of resistant mutants.
Topics: Acinetobacter; Ampicillin; Anti-Bacterial Agents; Bacteria; Cefotaxime; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Enterococcus faecalis; Gentamicins; Haemophilus influenzae; Mezlocillin; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Penicillin Resistance; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus | 1985 |
Incomplete cross-resistance of nalidixic and pipemidic acid-resistant variants of Serratia marcescens against ciprofloxacin, enoxacin, and norfloxacin.
Topics: Anti-Infective Agents, Urinary; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Nalidixic Acid; Naphthyridines; Norfloxacin; Pipemidic Acid; Quinolines; Serratia marcescens | 1985 |
Comparative in vitro activity of three new quinolone antibiotics against recent clinical isolates.
Topics: Anti-Bacterial Agents; Bacteria; Bacteroides fragilis; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus; Streptococcus | 1985 |
Comparative in vitro activities of aztreonam, ciprofloxacin, norfloxacin, ofloxacin, HR 810 (a new cephalosporin), RU28965 (a new macrolide), and other agents against enteropathogens.
Topics: Anti-Bacterial Agents; Aztreonam; Cefpirome; Cephalosporins; Ciprofloxacin; Enterobacteriaceae; Leucomycins; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1985 |
Antichlamydial activity of quinolone carboxylic acids.
Topics: Chlamydia trachomatis; Ciprofloxacin; Enoxacin; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1985 |
Inhibition of conjugal transfer by new quinolinic compounds.
Topics: 4-Quinolones; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Conjugation, Genetic; Escherichia coli; Nalidixic Acid; Norfloxacin; Quinolines; Quinolones | 1985 |
[Effect ofloxacin on Haemophilus influenza, Streptococcus pneumoniae and Neisseria meningitidis. Comparison with similar molecules].
Topics: Ciprofloxacin; Dose-Response Relationship, Drug; Haemophilus influenzae; Microbial Sensitivity Tests; Nalidixic Acid; Neisseria meningitidis; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Streptococcus pneumoniae | 1985 |
[Comparative in vitro study of the activity of 5 quinolones against Acinetobacter calcoaceticus].
Topics: Acinetobacter; Ciprofloxacin; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1985 |
In vitro antibacterial activity of imipenem in combination with newer quinolone derivatives.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Interactions; Drug Resistance, Microbial; Humans; Imipenem; Norfloxacin; Ofloxacin; Oxazines; Thienamycins | 1988 |
In vitro activity of lomefloxacin (SC-47111; NY-198), a difluoroquinolone 3-carboxylic acid, compared with those of other quinolones.
Topics: Anaerobiosis; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Magnesium; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Quinolones | 1988 |
Synthesis of some derivatives of 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(piperazin-1-yl)-3-quino linecarbo xylic acid (norfloxacin) as potential antibacterial agents.
Topics: Anti-Bacterial Agents; Bacteria; Chemical Phenomena; Chemistry; Ciprofloxacin; Microbial Sensitivity Tests; Norfloxacin | 1988 |
[The antibacterial effect of ciprofloxacin, ofloxacin and norfloxacin in vitro].
Topics: Bacteria; Ciprofloxacin; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin | 1988 |
In vitro activity of pefloxacin compared with five other quinolones on nalidixic acid-resistant proteae species.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; Pipemidic Acid; Proteus; Providencia; Urinary Tract Infections | 1988 |
In vitro activities of five new quinolones against 88 genital and neonatal Haemophilus isolates.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Enoxacin; Female; Genital Diseases, Female; Genital Diseases, Male; Haemophilus; Haemophilus Infections; Haemophilus influenzae; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1988 |
Studies on prodrugs. 7. Synthesis and antimicrobial activity of 3-formylquinolone derivatives.
Topics: Animals; Anti-Bacterial Agents; Biological Availability; Ciprofloxacin; Escherichia coli Infections; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Indicators and Reagents; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Norfloxacin; Pefloxacin; Pharmaceutical Preparations; Prodrugs; Structure-Activity Relationship | 1988 |
Bactericidal activity of ciprofloxacin, norfloxacin and ofloxacin in serum and urine after oral administration to healthy volunteers.
Topics: Administration, Oral; Ciprofloxacin; Escherichia coli; Humans; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines | 1988 |
In-vitro activity of antifungal agents in combination with four quinolones.
Topics: 4-Quinolones; Amphotericin B; Anti-Infective Agents; Antifungal Agents; Candida; Candida albicans; Ciprofloxacin; Drug Combinations; Enoxacin; Flucytosine; Mepartricin; Nalidixic Acid; Naphthyridines; Norfloxacin; Quinolines; Saccharomyces cerevisiae | 1988 |
[In vitro antibacterial activity of 2 new quinolones: A 56619 (difloxacin) and A 56620. Comparison with pefloxacin, ofloxacin and ciprofloxacin].
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
[Modulation by quinolones of the in vitro proliferative response of splenic cells of the mouse and IL 1 production].
Topics: Animals; Anti-Infective Agents; Cell Division; Cells, Cultured; Ciprofloxacin; Interleukin-1; Macrophages; Male; Mice; Mice, Inbred DBA; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid; Spleen | 1987 |
Fluoroquinolone derivatives: effects on neutrophil functional tests.
Topics: Anti-Infective Agents; Candida albicans; Chemotaxis, Leukocyte; Ciprofloxacin; Humans; In Vitro Techniques; Neutrophils; Norfloxacin; Ofloxacin; Pefloxacin; Phagocytosis; Staphylococcus aureus | 1987 |
Quinolones: their uses in geriatric infections.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Humans; Norfloxacin | 1988 |
Effects of quinolones on mitogen-stimulated human mononuclear leucocytes.
Topics: 4-Quinolones; Adult; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; In Vitro Techniques; Lymphocyte Activation; Norfloxacin; Phytohemagglutinins; Quinolines; Quinolones | 1988 |
Activity and mechanism of action of DuP 105 and DuP 721, new oxazolidinone compounds.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Gram-Negative Bacteria; Humans; Norfloxacin; Oxazoles; Oxazolidinones; Ribosomal Proteins; Staphylococcus; Streptococcus; Time Factors | 1988 |
Influence of quinolones on throat- and faecal flora of healthy volunteers.
Topics: Adult; Ciprofloxacin; Feces; Gram-Negative Bacteria; Humans; Male; Norfloxacin; Pharynx | 1987 |
The comparative pharmacokinetics and tissue penetration of four quinolones including intravenously administered enoxacin.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Half-Life; Humans; Kinetics; Male; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Tissue Distribution | 1986 |
Quinolone antimicrobial agents in acute exacerbations of chronic bronchitis.
Topics: Anti-Infective Agents; Bacterial Infections; Bronchitis; Ciprofloxacin; Enoxacin; Female; Humans; Male; Middle Aged; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1986 |
[Comparison of in vitro growth-inhibitory activities of ofloxacin, ciprofloxacin and norfloxacin against various species of mycobacteria (comparison of organ concentrations and blood concentrations in mice)].
Topics: Animals; Ciprofloxacin; Drug Resistance, Microbial; Male; Mice; Mycobacterium; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines | 1986 |
[Gyrase inhibitors: unwanted central nervous system effects].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Brain Chemistry; Brain Diseases; Ciprofloxacin; Enoxacin; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Solubility | 1987 |
The comparative in-vitro activity of eight newer quinolones and nalidixic acid.
Topics: Acinetobacter; Aeromonas; Anti-Bacterial Agents; Bacteria; Bacteria, Anaerobic; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fluoroquinolones; Gram-Positive Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Pefloxacin; Quinolines | 1986 |
The comparative pharmacokinetics of five quinolones.
Topics: Administration, Oral; Adult; Ciprofloxacin; Enoxacin; Half-Life; Humans; Infusions, Intravenous; Kinetics; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1986 |
Effects of quinolones on granulocyte function in vitro.
Topics: Anti-Infective Agents; Cell Survival; Ciprofloxacin; Hexosephosphates; Humans; Neutrophils; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Phagocytosis | 1986 |
Susceptibility of non-fermentative gram-negative bacteria to ciprofloxacin, norfloxacin, amifloxacin, pefloxacin and cefpirome.
Topics: Anti-Infective Agents; Cefpirome; Cephalosporins; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Microbial Sensitivity Tests; Norfloxacin; Pefloxacin; Quinolines | 1986 |
In-vitro selection of bacteria resistant to the 4-quinolone agents.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Staphylococcus; Streptococcus | 1987 |
CI-934, a new difluoroquinolone: in vitro antibacterial activity and proposed disk diffusion test interpretive criteria.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Regression Analysis | 1987 |
In vitro activity of CI-934 compared with ciprofloxacin, enoxacin, norfloxacin, and vancomycin.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Quinolines; Vancomycin | 1987 |
Comparative in vitro activities of pefloxacin, ofloxacin, enoxacin and ciprofloxacin against 256 clinical isolates.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Enoxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Comparative in vitro activity of ciprofloxacin, ofloxacin and pefloxacin against resistant clinical isolates.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Comparative in vitro activity of amifloxacin and five other fluoroquinolone antimicrobial agents and preliminary criteria for the disk susceptibility test.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
[Therapeutic contribution of the new quinolones].
Topics: Anti-Infective Agents; Bacterial Infections; Biotransformation; Chemical Phenomena; Chemistry; Ciprofloxacin; Drug Therapy, Combination; Humans; Kinetics; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
The adverse effects of fluoroquinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
New synthetic quinolone antibacterial agents and serum concentration of theophylline.
Topics: Adult; Anti-Infective Agents; Chemical Phenomena; Chemistry; Ciprofloxacin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Male; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid; Theophylline | 1987 |
In vitro susceptibility of Mycobacterium fortuitum, Mycobacterium chelonae and Mycobacterium avium against some quinolones.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines | 1987 |
Steady-state kinetics of the quinolone derivatives ofloxacin, enoxacin, ciprofloxacin and pefloxacin during maintenance treatment with theophylline.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Enoxacin; Female; Humans; Male; Middle Aged; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Theophylline | 1987 |
The influence of the 4-quinolones ciprofloxacin, pefloxacin and ofloxacin on the elimination of theophylline.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Lung Diseases, Obstructive; Male; Metabolic Clearance Rate; Middle Aged; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Theophylline | 1987 |
Quinolone penetration into canine vaginal and urethral secretions.
Topics: Animals; Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Dogs; Enoxacin; Female; Fluoroquinolones; Mucous Membrane; Naphthyridines; Norfloxacin; Quinolines; Urethra; Vagina | 1987 |
[Fluoroquinolones].
Topics: Bacteria; Chemical Phenomena; Chemistry; Ciprofloxacin; Enoxacin; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
Effects of quinolones on interleukin 1 production in vitro by human monocytes.
Topics: Adult; Anti-Infective Agents; Cell Division; Ciprofloxacin; HLA-DR Antigens; Humans; In Vitro Techniques; Interleukin-1; Kinetics; Monocytes; Norfloxacin; Pefloxacin; Penicillins; Phytohemagglutinins | 1987 |
Comparative effects of quinolones on human mononuclear leucocyte functions.
Topics: Cell Survival; Ciprofloxacin; Humans; Indomethacin; Interleukin-1; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Monocytes; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
In vitro activity of ciprofloxacin, norfloxacin, and ofloxacin against multi-resistant Enterobacteriaceae.
Topics: Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin | 1987 |
In vitro activity of E-3846, a new fluoroquinolone, against gram-negative and gram-positive bacteria.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Norfloxacin; Quinolones | 1987 |
In vivo evaluation of A-56619 (difloxacin) and A-56620: new aryl-fluoroquinolones.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Enterobacteriaceae Infections; Escherichia coli Infections; Female; Fluoroquinolones; Half-Life; Immunosuppression Therapy; Klebsiella Infections; Mice; Norfloxacin; Piperazines; Proteus Infections; Pseudomonas Infections; Pyelonephritis; Quinolines; Salmonella Infections, Animal; Staphylococcal Infections; Streptococcal Infections | 1986 |
The response of Escherichia coli to ciprofloxacin and norfloxacin.
Topics: Cell Wall; Ciprofloxacin; Cytoplasm; Drug Resistance, Microbial; Escherichia coli; Microscopy, Electron; Microscopy, Electron, Scanning; Nalidixic Acid; Norfloxacin; Vacuoles | 1987 |
Frequency and expression of mutational resistance to the 4-quinolone antibacterials.
Topics: 4-Quinolones; Anti-Bacterial Agents; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Escherichia coli; Fluoroquinolones; Mutation; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pipemidic Acid; Quinolines; Quinolizines; Quinolones | 1986 |
Activities of pefloxacin and ciprofloxacin against Mycobacterium leprae in the mouse.
Topics: Animals; Ciprofloxacin; Dapsone; Female; Half-Life; Kinetics; Leprosy; Mice; Mycobacterium leprae; Norfloxacin; Pefloxacin; Time Factors | 1987 |
Antibacterial activity of the metabolites of ciprofloxacin and its significance in the bioassay.
Topics: Bacteria; Ciprofloxacin; Dose-Response Relationship, Drug; Escherichia coli; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Structure-Activity Relationship | 1987 |
In vitro antibacterial activity of irloxacin (E-3432) on clinical isolates.
Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Nalidixic Acid; Norfloxacin; Quinolines | 1987 |
Assay of ciprofloxacin and norfloxacin in serum and urine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Humans; Kinetics; Norfloxacin | 1987 |
Comparison of in vitro activity of quinolone antibiotics and vancomycin against gentamicin- and methicillin-resistant Staphylococcus aureus by time-kill kinetic studies.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Gentamicins; Kinetics; Methicillin; Microbial Sensitivity Tests; Norfloxacin; Penicillin Resistance; Staphylococcus aureus; Vancomycin | 1986 |
In vitro activity of A-56619 and A56620, two new aryl-fluoroquinolone antimicrobial agents.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Norfloxacin; Piperazines; Quinolines | 1986 |
Determination of norfloxacin and ciprofloxacin concentrations in serum and urine by high-pressure liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Humans; Norfloxacin | 1986 |
[Evaluation of the effect of new fluoroderivatives of piperazinol-quinoline on clinical strains of aerobic and anaerobic bacteria].
Topics: Bacteroides; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Norfloxacin; Staphylococcus aureus | 1986 |
Synthesis and structure-activity relationships of novel arylfluoroquinolone antibacterial agents.
Topics: Acinetobacter; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Chemical Phenomena; Chemistry; Ciprofloxacin; Enterobacter; Escherichia coli; Female; Fluorine; Fluoroquinolones; Klebsiella pneumoniae; Mice; Norfloxacin; Pefloxacin; Piperazines; Pseudomonas aeruginosa; Quinolines; Staphylococcus; Streptococcus; Structure-Activity Relationship | 1985 |
Intraphagocytic bactericidal activity of bacterial DNA gyrase inhibitors against Serratia marcescens.
Topics: Blood Bactericidal Activity; Ciprofloxacin; Culture Media; Enoxacin; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Phagocytosis; Pipemidic Acid; Quinolines; Serratia marcescens; Topoisomerase II Inhibitors | 1984 |
Selection of multiple antibiotic resistance by quinolones, beta-lactams, and aminoglycosides with special reference to cross-resistance between unrelated drug classes.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Cefotaxime; Ciprofloxacin; Enterobacter; Enterobacteriaceae; Humans; Klebsiella pneumoniae; Mezlocillin; Mutation; Nalidixic Acid; Norfloxacin; Penicillin Resistance; Quinolines | 1984 |
Activities of newer quinolones against Legionella group organisms.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Legionella; Nalidixic Acid; Norfloxacin; Quinolines | 1983 |
In vitro activity of Bay 09867, a new quinoline derivative, compared with those of other antimicrobial agents.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Quinolines | 1983 |
In vitro activity of ciprofloxacin, norfloxacin and nalidixic acid.
Topics: Anti-Infective Agents, Urinary; Bacteria; Ciprofloxacin; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Quinolines | 1983 |
Comparative activities of ciprofloxacin (Bay o 9867), norfloxacin, pipemidic acid, and nalidixic acid.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Microbial Sensitivity Tests; Nalidixic Acid; Nicotinic Acids; Norfloxacin; Pipemidic Acid; Quinolines | 1983 |
In vitro activity of ciprofloxacin (Bay o 9867).
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Quinolines | 1983 |
In vitro activities of ciprofloxacin, norfloxacin, pipemidic acid, cinoxacin, and nalidixic acid against Chlamydia trachomatis.
Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Cinoxacin; Ciprofloxacin; Humans; Nalidixic Acid; Norfloxacin; Pipemidic Acid; Quinolines | 1984 |
Ciprofloxacin, a quinolone carboxylic acid compound active against aerobic and anaerobic bacteria.
Topics: Anti-Bacterial Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Ciprofloxacin; Drug Resistance, Microbial; Female; Humans; Male; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Norfloxacin; Protein Binding; Quinolines | 1984 |
The in-vitro activity of ciprofloxacin compared with that of norfloxacin and nalidixic acid.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Humans; Nalidixic Acid; Norfloxacin; Quinolines | 1984 |
In-vitro studies with ciprofloxacin, a new 4-quinolone compound.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Bacteria; Blood Proteins; Body Fluids; Ciprofloxacin; Culture Media; Drug Resistance, Microbial; Humans; Hydrogen-Ion Concentration; Nalidixic Acid; Norfloxacin; Protein Binding; Quinolines | 1984 |
Antibacterial activities of ciprofloxacin, norfloxacin, oxolinic acid, cinoxacin, and nalidixic acid.
Topics: Anti-Bacterial Agents; Cinoxacin; Ciprofloxacin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Micrococcaceae; Nalidixic Acid; Norfloxacin; Oxolinic Acid; Quinolines | 1984 |
Cross-resistance among cinoxacin, ciprofloxacin, DJ-6783, enoxacin, nalidixic acid, norfloxacin, and oxolinic acid after in vitro selection of resistant populations.
Topics: Anti-Bacterial Agents; Bacteria; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Enterobacteriaceae; Nalidixic Acid; Naphthyridines; Norfloxacin; Oxolinic Acid; Pseudomonas aeruginosa; Quinolines | 1984 |
In vitro activities of norfloxacin and ciprofloxacin against Mycobacterium tuberculosis, M. avium complex, M. chelonei, M. fortuitum, and M. kansasii.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Ciprofloxacin; Drug Interactions; Microbial Sensitivity Tests; Mycobacterium avium; Mycobacterium tuberculosis; Nalidixic Acid; Norfloxacin; Quinolines | 1984 |
A laboratory assessment of ciprofloxacin and comparable antimicrobial agents.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Microbial; Enoxacin; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Quinolines; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1984 |
Comparative in vitro activity of five quinoline derivatives and five other antimicrobial agents used in oral therapy.
Topics: Administration, Oral; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Dose-Response Relationship, Drug; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Pefloxacin; Pseudomonas; Quinolines; Respiratory Tract Infections; Trimethoprim; Urinary Tract Infections | 1984 |
The in vitro and in vivo activity of ciprofloxacin.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Dose-Response Relationship, Drug; Humans; Injections, Subcutaneous; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Quinolines | 1984 |
The activity of ciprofloxacin and other 4-quinolones against Chlamydia trachomatis and Mycoplasmas in vitro.
Topics: 4-Quinolones; Anti-Bacterial Agents; Chlamydia trachomatis; Ciprofloxacin; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Mycoplasma; Nalidixic Acid; Norfloxacin; Oxolinic Acid; Oxytetracycline; Quinolines; Quinolones; Ureaplasma | 1984 |
Mutational resistance to 4-quinolone antibacterial agents.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; Humans; Mutation; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Species Specificity | 1984 |
Comparison of the in vitro activity of ciprofloxacin (Bay o 9867) and norfloxacin against gastrointestinal tract pathogens.
Topics: Anti-Bacterial Agents; Campylobacter fetus; Ciprofloxacin; Gastroenteritis; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Quinolines; Salmonella; Shigella | 1984 |
In vitro activity of ciprofloxacin and norfloxacin against Gardnerella vaginalis.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Female; Gardnerella vaginalis; Haemophilus; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Quinolines | 1984 |
In vitro activity of ciprofloxacin against group JK corynebacteria.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Corynebacterium; Dose-Response Relationship, Drug; Humans; Nalidixic Acid; Norfloxacin; Quinolines | 1984 |
In vitro activities of the spectinomycin analog U-63366 and four quinolone derivatives against Neisseria gonorrhoeae.
Topics: 4-Quinolones; Anti-Bacterial Agents; Ciprofloxacin; Microbial Sensitivity Tests; Nalidixic Acid; Neisseria gonorrhoeae; Norfloxacin; Quinolines; Quinolones; Spectinomycin | 1984 |
Distribution of ciprofloxacin in the dog prostate and various tissues.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Body Fluids; Ciprofloxacin; Dogs; Hydrogen-Ion Concentration; Infusions, Parenteral; Male; Nalidixic Acid; Norfloxacin; Prostate; Quinolines; Quinolones; Tissue Distribution | 1984 |
Analysis of gyrA and grlA mutations in stepwise-selected ciprofloxacin-resistant mutants of Staphylococcus aureus.
Topics: Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Genes, Bacterial; Mutation; Norfloxacin; Staphylococcus aureus | 1995 |
Noncytotoxic combinations of topical antimicrobial agents for use with cultured skin substitutes.
Topics: Administration, Topical; Amphotericin B; Burns; Candida; Cells, Cultured; Ciprofloxacin; Culture Techniques; Drug Therapy, Combination; Enterobacteriaceae; Fibroblasts; Humans; Keratinocytes; Microbial Sensitivity Tests; Norfloxacin; Nystatin; Skin; Skin, Artificial; Staphylococcus aureus | 1995 |
Topical 0.3% ciprofloxacin, norfloxacin, and ofloxacin in treatment of bacterial keratitis: a new method for comparative evaluation of ocular drug penetration.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Chromatography, High Pressure Liquid; Ciprofloxacin; Cornea; Drug Therapy, Combination; Eye Infections, Bacterial; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Keratitis; Male; Microbial Sensitivity Tests; Middle Aged; Norfloxacin; Ofloxacin; Ophthalmic Solutions | 1995 |
Determination of the susceptibility in vitro of 54 isolates of Mycobacterium fortuitum against three fluoroquinolones using two methods.
Topics: Anti-Infective Agents; Ciprofloxacin; Microbial Sensitivity Tests; Mycobacterium; Norfloxacin; Ofloxacin | 1995 |
Tandem scanning confocal microscopic analysis of ciprofloxacin corneal deposits in vivo.
Topics: Administration, Topical; Animals; Calcinosis; Chemical Precipitation; Ciprofloxacin; Cornea; Corneal Diseases; Epithelium; Humans; Hydrogen-Ion Concentration; Male; Microscopy, Confocal; Middle Aged; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Rabbits; Random Allocation; Tears; Wound Healing | 1995 |
Function of the SOS process in repair of DNA damage induced by modern 4-quinolones.
Topics: Anti-Infective Agents; Cell Division; Ciprofloxacin; DNA Damage; DNA Repair; DNA, Bacterial; Escherichia coli; Mutation; Nalidixic Acid; Norfloxacin; Ofloxacin; RNA, Bacterial; SOS Response, Genetics | 1993 |
Stimulation of genetic instability and associated large genomic rearrangements in Streptomyces ambofaciens by three fluoroquinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA, Bacterial; Enoxacin; Gene Amplification; Gene Deletion; Gene Rearrangement; Genome, Bacterial; Humans; Models, Biological; Mutation; Norfloxacin; Pigmentation; Stimulation, Chemical; Streptomyces | 1994 |
In-vitro activity of new sulphanilil fluoroquinolones against Staphylococcus aureus.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Methicillin Resistance; Microbial Sensitivity Tests; Norfloxacin; Quinolones; Staphylococcal Infections; Staphylococcus aureus; Time Factors | 1994 |
Antibiotic susceptibility pattern of gonococcal isolates.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Norfloxacin; Penicillin Resistance; Urethritis | 1994 |
In vitro activity of subinhibitory concentrations of quinolones on urea-splitting bacteria: effect on urease activity and on cell surface hydrophobicity.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enterobacteriaceae; Fluoroquinolones; Norfloxacin; Ofloxacin; Proteus; Providencia; Quinolones; Surface Properties; Urea; Urease | 1995 |
In vitro phototoxic activities of new quinolone antibacterial agents: lipid peroxidative potentials.
Topics: Absorption; Anti-Infective Agents; Azides; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Lipid Peroxidation; Norfloxacin; Ofloxacin; Oxygen; Photochemistry; Photosensitivity Disorders; Quinolones; Sodium Azide; Squalene; Ultraviolet Rays | 1994 |
Resistance to fluoroquinolones in Pseudomonas aeruginosa and Klebsiella pneumoniae.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Norfloxacin; Pseudomonas aeruginosa | 1994 |
[Quinolone-resistant Escherichia coli in the health area of a 650-bed hospital].
Topics: Catchment Area, Health; Ciprofloxacin; Drug Resistance, Microbial; Escherichia coli; Hospital Bed Capacity, 500 and over; Humans; Microbial Sensitivity Tests; Norfloxacin; Pipemidic Acid; Retrospective Studies; Spain; Urinary Tract Infections | 1994 |
Effects of ciprofloxacin, norfloxacin, and ofloxacin on in vitro adhesion and survival of Pseudomonas aeruginosa AK1 on urinary catheters.
Topics: Anti-Infective Agents; Bacterial Adhesion; Biofilms; Chromatography, High Pressure Liquid; Ciprofloxacin; Equipment Contamination; Humans; Microscopy, Electron, Scanning; Norfloxacin; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Spectrophotometry, Ultraviolet; Urinary Catheterization | 1994 |
Dissociation and complexation of fluoroquinolone analogues.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Ferric Compounds; Models, Theoretical; Norfloxacin; Ofloxacin; Spectrophotometry | 1994 |
The effect of temperature and pH on the solubility of quinolone compounds: estimation of heat of fusion.
Topics: Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Ciprofloxacin; Hot Temperature; Hydrogen-Ion Concentration; Norfloxacin; Quinolones; Solubility; Temperature; Thermodynamics | 1994 |
Interference of ofloxacin with determination of urinary porphyrins.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; False Positive Reactions; Humans; Nalidixic Acid; Norfloxacin; Ofloxacin; Porphyrins; Spectrometry, Fluorescence | 1994 |
Comparative study of permeability into rat cerebrospinal fluid of the quinolones: dependency on their lipophilicities.
Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Injections, Intravenous; Male; Nalidixic Acid; Norfloxacin; Ofloxacin; Rats; Rats, Wistar | 1994 |
Antagonism between bactericidal activities of 4-quinolones and coumarins gives insight into 4-quinolone killing mechanisms.
Topics: Aminocoumarins; Anti-Infective Agents; Ciprofloxacin; Coumarins; DNA Topoisomerases, Type II; Escherichia coli; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Norfloxacin; Novobiocin; Ofloxacin; Rifampin | 1994 |
Active intestinal secretion of the fluoroquinolone antibacterials ciprofloxacin, norfloxacin and pefloxacin; a common secretory pathway?
Topics: Biological Transport; Carbon Radioisotopes; Cells, Cultured; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Humans; Intestinal Mucosa; Norfloxacin; Ofloxacin; Pefloxacin; Quinolizines | 1994 |
Simultaneous determination of ofloxacin, norfloxacin and ciprofloxacin in human hair by high-performance liquid chromatography and fluorescence detection.
Topics: Adult; Chromatography, High Pressure Liquid; Ciprofloxacin; Hair; Humans; Middle Aged; Norfloxacin; Ofloxacin; Reproducibility of Results; Spectrometry, Fluorescence; Spectrum Analysis | 1994 |
High prevalence of Neisseria gonorrhoeae strains with reduced susceptibility to fluoroquinolones in Japan.
Topics: Chi-Square Distribution; Ciprofloxacin; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Serotyping; Urethritis | 1994 |
Correlation between umuC induction and Salmonella mutagenicity assay for quinolone antimicrobial agents.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; DNA-Directed DNA Polymerase; Enoxacin; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Gene Expression Regulation, Bacterial; Mutagenicity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Quinolones; Salmonella typhimurium; SOS Response, Genetics; Species Specificity | 1993 |
[Evolution of fluoroquinolone sensitivity in Staphylococcus aureus isolated from hemocultures in a general hospital].
Topics: Bacteremia; Blood; Ciprofloxacin; Cross Infection; Drug Resistance, Microbial; Hospitals, General; Humans; Norfloxacin; Staphylococcal Infections; Staphylococcus aureus | 1993 |
Simultaneous assay of fluoroquinolones and theophylline in plasma by high-performance liquid chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Male; Norfloxacin; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Theophylline | 1993 |
Fixed eruption caused by ciprofloxacin with cross-sensitivity to norfloxacin.
Topics: Aged; Ciprofloxacin; Drug Eruptions; Drug Interactions; Female; Humans; Norfloxacin; Skin Tests | 1993 |
Ten-year survey of quinolone resistance in Escherichia coli causing urinary tract infections.
Topics: Anti-Infective Agents; Ciprofloxacin; Data Collection; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Infections; Humans; Longitudinal Studies; Norfloxacin; Pipemidic Acid; Urinary Tract Infections | 1993 |
Induction of resistance of Streptococcus pneumoniae to quinolones in vitro.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones; Streptococcus pneumoniae | 1993 |
The in-vitro activity of OPC-17116, a new 5-methyl substituted quinolone.
Topics: Amoxicillin; Anti-Infective Agents; Bacteroides fragilis; Cefaclor; Chlamydia trachomatis; Chlamydophila pneumoniae; Ciprofloxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Norfloxacin; Piperazines; Protein Binding; Quinolones; Staphylococcus | 1993 |
Developmental toxicity of fleroxacin and comparative pharmacokinetics of four fluoroquinolones in the cynomolgus macaque (Macaca fascicularis).
Topics: Administration, Oral; Animals; Anti-Infective Agents; Ciprofloxacin; Embryo, Mammalian; Female; Fleroxacin; Fluoroquinolones; Macaca fascicularis; Norfloxacin; Pregnancy; Pregnancy, Animal; Quinolones | 1993 |
In vitro activity of fluoroquinolones against chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum.
Topics: Animals; Chloroquine; Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Plasmodium falciparum | 1993 |
The new fluorinated quinolones for antimicrobial prophylaxis in neutropenic cancer patients.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Therapy, Combination; Gram-Negative Bacterial Infections; Humans; Neoplasms; Neutropenia; Norfloxacin; Prospective Studies; Randomized Controlled Trials as Topic | 1993 |
In vitro and in vivo antibacterial activities of T-3761, a new quinolone derivative.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Lung Diseases; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Urinary Tract Infections | 1993 |
Evaluation of the efficacy of different antibiotics in inhibiting colonisation of Vibrio cholerae O1 in the rabbit intestine.
Topics: Animals; Anti-Bacterial Agents; Cholera; Ciprofloxacin; Disease Models, Animal; Evaluation Studies as Topic; Intestines; Microbial Sensitivity Tests; Norfloxacin; Rabbits; Tetracycline; Vibrio cholerae | 1993 |
Emergence of bacterial resistance to imipenem and ciprofloxacin in a university hospital.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Cross Infection; Drug Resistance, Microbial; Drug Utilization; Humans; Imipenem; Microbial Sensitivity Tests; Norfloxacin; Oxacillin; Penicillins; Thienamycins | 1995 |
Topoisomerase IV is a target of quinolones in Escherichia coli.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Replication; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA, Bacterial; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; Mutation; Norfloxacin; Nucleic Acid Conformation; Quinolones | 1995 |
Proposed criteria for interpretation of susceptibilities of strains of Neisseria gonorrhoeae to ciprofloxacin, ofloxacin, enoxacin, lomefloxacin, and norfloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Diffusion; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Quinolones | 1995 |
In vitro antibacterial activity of FA103, a new quinolone derivative of C-7 position with 7-perhydrodiazepinone.
Topics: Anti-Infective Agents; Azepines; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Norfloxacin; Ofloxacin; Quinolones | 1995 |
Fixed eruption caused by ciprofloxacin without cross-sensitivity to norfloxacin.
Topics: Ciprofloxacin; Cross Reactions; Drug Eruptions; Exanthema; Female; Humans; Middle Aged; Norfloxacin; Respiratory Tract Infections | 1995 |
Modulation of biofilms of Pseudomonas aeruginosa by quinolones.
Topics: Anti-Infective Agents; Bacterial Adhesion; Biofilms; Catheterization; Ciprofloxacin; Glycoproteins; Norfloxacin; Ofloxacin; Pefloxacin; Polysaccharides; Pseudomonas aeruginosa | 1995 |
Use of the new quinolones during pregnancy.
Topics: Abnormalities, Drug-Induced; Anti-Infective Agents; Child, Preschool; Ciprofloxacin; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Norfloxacin; Pregnancy; Pregnancy Trimester, First; Risk Factors; Urinary Tract Infections | 1996 |
A comparison of ciprofloxacin, norfloxacin, ofloxacin, azithromycin and cefixime examined by observational cohort studies.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Cefotaxime; Ciprofloxacin; Cohort Studies; Drug Prescriptions; Female; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Pregnancy; Product Surveillance, Postmarketing; Treatment Outcome | 1996 |
Spectrophotometric and spectrofluorimetric estimation of ciprofloxacin and norfloxacin by ternary complex formation with eosin and palladium(II).
Topics: Anti-Infective Agents; Ciprofloxacin; Eosine Yellowish-(YS); Hydrogen-Ion Concentration; Norfloxacin; Palladium; Spectrometry, Fluorescence; Spectrophotometry; Tablets; Temperature | 1996 |
Pharmacokinetics of topically applied ciprofloxacin in rabbit tears.
Topics: Animals; Anti-Infective Agents; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Rabbits; Tears | 1996 |
[Comparative study of the antimicrobial activity of pefloxacin, ciprofloxacin, norfloxacin and azithromycin with respect to Strains of Yersinia pseudotuberculosis].
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Ciprofloxacin; Humans; Microbial Sensitivity Tests; Norfloxacin; Pefloxacin; Yersinia pseudotuberculosis | 1996 |
Sequential mutations of gyrA in Escherichia coli associated with quinolone therapy.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Codon; DNA Gyrase; DNA Topoisomerases, Type II; Escherichia coli; Humans; Mutation; Norfloxacin; Plasmids; Urinary Tract Infections | 1995 |
[Determination of antimycobacterial activities of fluoroquinolones against clinical isolates of Mycobacterium tuberculosis: comparative determination with egg-based Ogawa and agar-based Middlebrook 7H10 media].
Topics: Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Culture Media; Fluoroquinolones; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Quinolones | 1996 |
Gyrase mutations in laboratory-selected, fluoroquinolone-resistant mutants of Mycobacterium tuberculosis H37Ra.
Topics: Anti-Infective Agents; Antitubercular Agents; Base Sequence; Cell Wall; Cephaloridine; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Permeability; Quinolones | 1996 |
Fluoroquinolone antibiotics inhibit cytochrome P450-mediated microsomal drug metabolism in rat and human.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Isoenzymes; Microsomes, Liver; Norfloxacin; Rats | 1996 |
Intermolecular interactions of antimicrobial fluoroquinolones with purified rat liver CYP1A2 studied by proton nuclear magnetic resonance spectroscopy.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Cytochrome P-450 CYP1A2; Enoxacin; Fluoroquinolones; Liver; Magnetic Resonance Spectroscopy; Male; Norfloxacin; Phenacetin; Rats; Rats, Wistar | 1996 |
Evaluation of 500 gram negative isolates to determine the number of major susceptibility interpretation discrepancies between the Vitek and MicroScan Walkaway for 9 antimicrobial agents.
Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Clavulanic Acid; Clavulanic Acids; Enterobacter; Escherichia coli; Imipenem; Klebsiella pneumoniae; Mezlocillin; Microbial Sensitivity Tests; Norfloxacin; Penicillins; Piperacillin; Proteus mirabilis; Pseudomonas aeruginosa; Quality Control; Reproducibility of Results; Sulbactam; Thienamycins; Ticarcillin | 1996 |
[Evolution of susceptibilities of Campylobacter jejuni isolated from diarrhoeal cases to fluoroquinolones in Tokyo].
Topics: Anti-Infective Agents; Campylobacter jejuni; Ciprofloxacin; Diarrhea; Drug Resistance, Microbial; Humans; Norfloxacin; Ofloxacin; Tokyo | 1996 |
False-positive EMIT II opiates from ofloxacin.
Topics: Anti-Infective Agents; Antibodies; Ciprofloxacin; Cross Reactions; Enzyme Multiplied Immunoassay Technique; False Positive Reactions; Humans; Morphine; Nalidixic Acid; Norfloxacin; Ofloxacin | 1997 |
[Elimination of virulence plasmids of Yersinia pseudotuberculosis as affected by fluoroquinolones].
Topics: Anti-Infective Agents; Ciprofloxacin; Microbial Sensitivity Tests; Molecular Weight; Norfloxacin; Pefloxacin; Plasmids; Virulence; Yersinia pseudotuberculosis | 1996 |
Absorption of ciprofloxacin and norfloxacin when administered as niosome-encapsulated inclusion complexes.
Topics: Absorption; Administration, Intranasal; Administration, Oral; Animals; Anti-Infective Agents; Area Under Curve; beta-Cyclodextrins; Ciprofloxacin; Cyclodextrins; Drug Carriers; Drug Stability; Liposomes; Norfloxacin; Rats; Temperature | 1997 |
Enhanced hematopoiesis in sublethally irradiated mice treated with various quinolones.
Topics: Animals; Anti-Infective Agents; Bone Marrow; Cells, Cultured; Ciprofloxacin; Cobalt Radioisotopes; Colony-Forming Units Assay; Culture Media, Conditioned; Fleroxacin; Fluoroquinolones; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cells; Hemoglobins; Interleukin-3; Leukocyte Count; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Norfloxacin; Ofloxacin; Quinolones; Whole-Body Irradiation | 1997 |
Enteropathogens associated with diarrhea among military personnel during Operation Bright Star 96, in Alexandria, Egypt.
Topics: Ampicillin Resistance; Animals; Anti-Infective Agents; Antigens, Bacterial; Bacterial Proteins; Blastocystis hominis; Blastocystis Infections; Chloramphenicol Resistance; Ciprofloxacin; Cryptosporidiosis; Diarrhea; Dientamoebiasis; Dysentery, Amebic; Egypt; Entamoeba; Entamoeba histolytica; Escherichia coli; Escherichia coli Infections; Eukaryota; Fimbriae Proteins; Humans; Military Personnel; Nalidixic Acid; Norfloxacin; Pili, Sex; Protozoan Infections; Tetracycline Resistance; United States | 1997 |
Fixed drug eruption (FDE) caused by norfloxacin.
Topics: Aged; Anti-Infective Agents; Biopsy; Ciprofloxacin; Drug Eruptions; Female; Humans; Norfloxacin; Patch Tests | 1997 |
The role of fluoroquinolones in the promotion of alginate synthesis and antibiotic resistance in Pseudomonas aeruginosa.
Topics: Alginates; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Glucuronic Acid; Hexuronic Acids; Norfloxacin; Ofloxacin; Pseudomonas aeruginosa | 1997 |
In-vitro activity of trovafloxacin against clinical bacterial isolates from patients with cancer.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Neoplasms; Norfloxacin; Ofloxacin; Quinolones | 1997 |
Antibacterial activity of trovafloxacin against nosocomial Gram-positive and Gram-negative isolates.
Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Cross Infection; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Lactams; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin | 1997 |
Inhibitory effect of new quinolones on GABA(A) receptor-mediated response and its potentiation with felbinac in Xenopus oocytes injected with mouse-brain mRNA: correlation with convulsive potency in vivo.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Bicuculline; Brain Chemistry; Cells, Cultured; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Synergism; Enoxacin; Female; GABA-A Receptor Antagonists; Injections, Intraventricular; Male; Membrane Potentials; Mice; Microinjections; Norfloxacin; Oocytes; Phenylacetates; Receptors, GABA-A; RNA, Messenger; Seizures; Xenopus laevis | 1997 |
Development of a rapid assay for detecting gyrA mutations in Escherichia coli and determination of incidence of gyrA mutations in clinical strains isolated from patients with complicated urinary tract infections.
Topics: Anti-Infective Agents; Asparagine; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Infections; Genes, Bacterial; Humans; Incidence; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Serine; Urinary Tract Infections | 1997 |
Application of terbium sensitized fluorescence for the determination of fluoroquinolone antibiotics pefloxacin, ciprofloxacin and norfloxacin in serum.
Topics: Anti-Infective Agents; Cetylpyridinium; Ciprofloxacin; Fluorescence; Humans; Hydrogen-Ion Concentration; Norfloxacin; Organophosphorus Compounds; Pefloxacin; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Terbium; Time Factors | 1997 |
Minimum inhibitory concentration (MIC) of some antibiotics against Vibrio cholerae O139 isolates from Pondicherry.
Topics: Ampicillin; Anti-Bacterial Agents; Cefotaxime; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Furazolidone; Gentamicins; India; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; O Antigens; Tetracycline; Trimethoprim, Sulfamethoxazole Drug Combination; Vibrio cholerae | 1997 |
The beneficial effects of ciprofloxacin on survival and hepatic regenerative activity in a rat model of fulminant hepatic failure.
Topics: Alanine Transaminase; Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; DNA; Immunohistochemistry; Liver Failure; Liver Regeneration; Male; Norfloxacin; Proliferating Cell Nuclear Antigen; Putrescine; Rats; Rats, Sprague-Dawley; Survival Rate; Time Factors | 1998 |
Penetration of ciprofloxacin, norfloxacin and ofloxacin into the aqueous humours of patients by different topical application modes.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Aqueous Humor; Ciprofloxacin; Female; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Prospective Studies | 1997 |
Hydrophobicity and serum sensitivity of Klebsiella pneumoniae treated with sub-MICs of quinolones.
Topics: Anti-Infective Agents; Blood Bactericidal Activity; Cell Membrane; Ciprofloxacin; Enoxacin; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Norfloxacin; Respiratory System; Surface Properties | 1997 |
Antibiotic sensitivity and proticine typing of Proteus mirabilis strains associated with rheumatoid arthritis.
Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Arthritis, Rheumatoid; Bacteriocins; Case-Control Studies; Ciprofloxacin; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Norfloxacin; Proteus Infections; Proteus mirabilis; Serotyping; Trimethoprim | 1998 |
Antimicrobial resistance in gonococci isolated from patients and from commercial sex workers in Harare, Zimbabwe.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactam Resistance; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Female; Gonorrhea; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Penicillinase; Sex Work; Zimbabwe | 1997 |
Emergence of ciprofloxacin resistance in Escherichia coli isolates after widespread use of fluoroquinolones.
Topics: Aged; Anti-Bacterial Agents; Ciprofloxacin; Contraindications; Drug Resistance, Microbial; Drug Utilization; Escherichia coli; Humans; Linear Models; Norfloxacin | 1998 |
Urinary bactericidal activity and pharmacokinetics of enoxacin versus norfloxacin and ciprofloxacin in healthy volunteers after a single oral dose.
Topics: Administration, Oral; Adult; Bacteriuria; Calibration; Chromatography, High Pressure Liquid; Ciprofloxacin; Cross-Over Studies; Enoxacin; Enterococcus faecalis; Escherichia coli; Female; Humans; Klebsiella pneumoniae; Male; Metabolic Clearance Rate; Microbial Sensitivity Tests; Norfloxacin; Proteus mirabilis; Pseudomonas aeruginosa; Random Allocation; Reference Values; Spectrophotometry, Ultraviolet; Time Factors | 1998 |
In vitro susceptibility of multiple drug resistant Salmonella typhimurium to newer fluroquinolone derivatives.
Topics: Anti-Infective Agents; Ciprofloxacin; Diarrhea, Infantile; Drug Resistance, Multiple; Humans; In Vitro Techniques; Infant; Norfloxacin; Ofloxacin; Salmonella Infections; Salmonella typhimurium | 1995 |
[Observation of 212 cases of typhoid fever treated with FQNS].
Topics: Adult; Anti-Infective Agents; Child; Ciprofloxacin; Enoxacin; Humans; Norfloxacin; Recurrence; Typhoid Fever | 1997 |
Effects of NorA inhibitors on in vitro antibacterial activities and postantibiotic effects of levofloxacin, ciprofloxacin, and norfloxacin in genetically related strains of Staphylococcus aureus.
Topics: Anti-Infective Agents; Bacterial Proteins; Biological Transport; Ciprofloxacin; Drug Synergism; Humans; Levofloxacin; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Norfloxacin; Ofloxacin; Staphylococcal Infections; Staphylococcus aureus; Time Factors | 1999 |
Penetration of ciprofloxacin, norfloxacin and ofloxacin into the aqueous humor using different topical application modes.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Aqueous Humor; Bacteria; Biological Availability; Cataract Extraction; Chromatography, High Pressure Liquid; Ciprofloxacin; Cornea; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Prospective Studies | 1999 |
Mechanisms of quinolone resistance in clinical strains of Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Microbial; Fluoroquinolones; Humans; Mutation; Naphthyridines; Norfloxacin; Pseudomonas aeruginosa; Transcription Factors | 1998 |
Synthesis and methemoglobin toxicity of the amides of 6/7 mono or disubstituted quinolone.
Topics: Amides; Animals; Anti-Infective Agents; Ciprofloxacin; Cytochrome-B(5) Reductase; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Methemoglobin; Methemoglobinemia; Norfloxacin; Ofloxacin; Quinolones; Structure-Activity Relationship | 1999 |
Infections caused by Escherichia coli resistant to norfloxacin in hospitalized cirrhotic patients.
Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Drug Therapy, Combination; Escherichia coli; Escherichia coli Infections; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Norfloxacin; Ofloxacin; Time Factors; Treatment Outcome | 1999 |
Post-antibiotic effect of quinolones on Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Norfloxacin; Pseudomonas aeruginosa | 1999 |
Electrophoretic behaviour of quinolones in capillary electrophoresis. Effect of pH and evaluation of ionization constants.
Topics: Anti-Infective Agents; Chemical Phenomena; Chemistry, Physical; Ciprofloxacin; Electrophoresis, Capillary; Fluoroquinolones; Hydrogen-Ion Concentration; Ions; Mathematics; Models, Chemical; Molecular Structure; Norfloxacin; Quinolones; Solutions; Water | 1999 |
The effects of NorA inhibition on the activities of levofloxacin, ciprofloxacin and norfloxacin against two genetically related strains of Staphylococcus aureus in an in-vitro infection model.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; Drug Interactions; Drug Resistance, Microbial; Enzyme Inhibitors; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Multidrug Resistance-Associated Proteins; Norfloxacin; Ofloxacin; Omeprazole; Species Specificity; Staphylococcal Infections; Staphylococcus aureus | 1999 |
In vitro phototoxicity of new quinolones: production of active oxygen species and photosensitized lipid peroxidation.
Topics: Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; DNA Damage; Fleroxacin; Fluoroquinolones; Humans; Lipid Peroxidation; Norfloxacin; Ofloxacin; Quinolones; Reactive Oxygen Species; Squalene; Time Factors; Ultraviolet Rays | 1999 |
In vitro antimalarial activity of trovafloxacin, a fourth-generation fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Fluoroquinolones; Naphthyridines; Norfloxacin; Plasmodium falciparum | 2000 |
Molecular mechanisms of fluoroquinolone resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients.
Topics: Adult; Anti-Infective Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; Ciprofloxacin; Cystic Fibrosis; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Microbial; Electrophoresis, Gel, Pulsed-Field; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Norfloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA; Transcription Factors | 2000 |
Nonstoichiometric hydroxyapatite-anionic collagen composite as support for the double sustained release of gentamicin and norfloxacin/ciprofloxacin.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Biocompatible Materials; Biodegradation, Environmental; Bone Diseases; Calcium; Chelating Agents; Ciprofloxacin; Collagen; Delayed-Action Preparations; Diffusion; Drug Carriers; Drug Delivery Systems; Durapatite; Gentamicins; Gram-Negative Bacteria; Male; Norfloxacin; Osteogenesis; Rats | 2000 |
Antibiotics sensitivity pattern of N. gonorrhoeae with special emphasis on norfloxacin and ciprofloxacin.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Urethritis | 1999 |
Roles of gyrA mutations in resistance of clinical isolates and in vitro mutants of Bacteroides fragilis to the new fluoroquinolone trovafloxacin.
Topics: Anti-Infective Agents; Bacteroides fragilis; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mutation; Naphthyridines; Norfloxacin | 2000 |
[The effect of fluoroquinolones on the adhesive properties of different plasmidovars of Yersinia pseudotuberculosis].
Topics: Anti-Infective Agents; Bacterial Adhesion; Ciprofloxacin; Erythrocytes; Humans; In Vitro Techniques; Norfloxacin; Pefloxacin; Plasmids; Serotyping; Yersinia pseudotuberculosis | 2000 |
Effect of suprainhibitory concentrations of quinolones on hydrophobicity and motility of Serratia marcescens.
Topics: Anti-Infective Agents; Cell Division; Ciprofloxacin; Dose-Response Relationship, Drug; Enoxacin; Movement; Norfloxacin; Serratia marcescens; Virulence | 2000 |
Selective targeting of topoisomerase IV and DNA gyrase in Staphylococcus aureus: different patterns of quinolone-induced inhibition of DNA synthesis.
Topics: Anti-Infective Agents; Chromosomes, Bacterial; Ciprofloxacin; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA, Bacterial; Kinetics; Macromolecular Substances; Nalidixic Acid; Norfloxacin; Staphylococcus aureus; Topoisomerase II Inhibitors | 2000 |
[Accumulation and efflux of quinolones by clinical isolates of Stenotrophomonas maltophilia].
Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Biological Transport, Active; Blotting, Western; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Membrane Potentials; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Stenotrophomonas maltophilia; Uncoupling Agents | 2000 |
Study on three-dimensional fluorescent spectral characteristics of fluoroquinolones in varying media.
Topics: Acids; Anti-Infective Agents; Ciprofloxacin; Dioctyl Sulfosuccinic Acid; Micelles; Norfloxacin; Ofloxacin; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Water | 2000 |
In vitro selection of fluoroquinolone-resistant Neisseria gonorrhoeae harboring alterations in DNA gyrase and topoisomerase IV.
Topics: Anti-Infective Agents; Aspartic Acid; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Genes, Bacterial; Glutamic Acid; Humans; Microbial Sensitivity Tests; Mutation; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Selection, Genetic; Serine | 2000 |
Antimicrobial activity of gemifloxacin (SB-265805), a newer fluoroquinolone, against clinical isolates of Neisseria gonorrhoeae, including fluoroquinolone-resistant isolates.
Topics: Amoxicillin; Anti-Infective Agents; Ciprofloxacin; Clavulanic Acid; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Gonorrhea; Humans; Levofloxacin; Naphthyridines; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin | 2000 |
In vitro and in vivo investigations on fluoroquinolones; effects of the P-glycoprotein efflux transporter on brain distribution of sparfloxacin.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Antitubercular Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Cell Line; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Infusions, Intra-Arterial; Kidney; Mice; Mice, Inbred Strains; Mice, Knockout; Microdialysis; Norfloxacin; Pefloxacin; Recombinant Proteins; Rhodamine 123; Swine; Tissue Distribution; Transfection | 2000 |
Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones.
Topics: Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Cytoplasm; Fibroblasts; Fluoroquinolones; Humans; Mitochondria; Norfloxacin; Ofloxacin; Photosensitizing Agents; Quinolones; Skin | 2000 |
Seasonal variation in fluoroquinolone prescribing.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Utilization Review; England; Humans; Norfloxacin; Ofloxacin; Seasons; Urinary Tract Infections | 1999 |
Antimicrobial resistance of Enterococci in Lebanon.
Topics: Aminoglycosides; Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Chloramphenicol; Ciprofloxacin; Drug Resistance, Microbial; Enterococcus; Erythromycin; Gentamicins; Humans; Lebanon; Microbial Sensitivity Tests; Norfloxacin; Penicillins; Rifampin; Streptomycin; Teicoplanin; Tetracycline; Vancomycin | 2001 |
Development of an indirect competitive ELISA for ciprofloxacin residues in food animal edible tissues.
Topics: Animals; Animals, Domestic; Cattle; Ciprofloxacin; Cross Reactions; Drug Residues; Enzyme-Linked Immunosorbent Assay; Humans; Meat; Norfloxacin; Serum Albumin; Serum Albumin, Bovine | 2001 |
Fluorescence characteristic study of the ternary complex of fluoroquinolone antibiotics and cobalt (II) with ATP.
Topics: Adenosine Triphosphate; Anti-Infective Agents; Ciprofloxacin; Cobalt; Fluorescence; Molecular Structure; Norfloxacin; Ofloxacin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2001 |
In vitro activity of levofloxacin against coagulase-positive and -negative staphylococci.
Topics: Anti-Infective Agents; Ciprofloxacin; Coagulase; Drug Resistance, Microbial; Levofloxacin; Methicillin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Penicillins; Staphylococcus | 2001 |
The impact of norfloxacin, ciprofloxacin and ofloxacin on human gut colonization by Candida albicans.
Topics: Adult; Aged; Anti-Infective Agents; Candida albicans; Ciprofloxacin; Digestive System; Female; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Urinary Tract Infections | 2001 |
Interaction between biofilms formed by Staphylococcus epidermidis and quinolones.
Topics: Anti-Infective Agents; Bacterial Adhesion; Biofilms; Catheterization; Ciprofloxacin; Dose-Response Relationship, Drug; Glycocalyx; Microbial Sensitivity Tests; Models, Biological; Norfloxacin; Pefloxacin; Staphylococcus epidermidis | 2001 |
Trace determination of fluoroquinolone antibacterial agents in urban wastewater by solid-phase extraction and liquid chromatography with fluorescence detection.
Topics: Anti-Infective Agents; Chromatography, Liquid; Ciprofloxacin; Environmental Monitoring; Fluorescence; Ion Exchange; Mass Spectrometry; Medical Waste; Norfloxacin; Sewage; Switzerland; Urbanization; Water Pollutants, Chemical | 2001 |
Comparison of the in vitro activities of BMS-284756 and four fluoroquinolones against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Moxifloxacin; Norfloxacin; Quinolines; Quinolones; Streptococcus pneumoniae | 2001 |
The fungus Pestalotiopsis guepini as a model for biotransformation of ciprofloxacin and norfloxacin.
Topics: Anti-Infective Agents; Biodegradation, Environmental; Chromatography, High Pressure Liquid; Ciprofloxacin; Culture Media, Conditioned; Fungi; Magnetic Resonance Spectroscopy; Norfloxacin | 2001 |
[Degradation of liquid preparations of four fluoroquinolones by factorial experiment. ].
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Light; Norfloxacin; Ofloxacin; Quinolones | 1997 |
[Studies on pyridonecarboxylic acids as antibacterial agents. XII. Synthesis and antibacterial activity of 6-chloro-1-cyclopropyl-7-(1-piperazinyl)-1, 4-dihydro-4-oxo-quinoline-3-carboxylic acid and analogues].
Topics: Animals; Anti-Infective Agents; Carboxylic Acids; Ciprofloxacin; Escherichia coli; Mice; Norfloxacin; Pseudomonas aeruginosa; Pyridones; Quinolones; Staphylococcal Infections; Staphylococcus aureus | 1997 |
[The activity of four fluoroquinolones against strains of Pseudomonas aeruginosa with a different sensitivity pattern to ceftazidime and imipenem].
Topics: 4-Quinolones; Anti-Infective Agents; Ceftazidime; Ciprofloxacin; Drug Resistance; Fluoroquinolones; Humans; Imipenem; Microbial Sensitivity Tests; Norfloxacin; Pefloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Spain | 2001 |
Accumulation of five fluoroquinolones by Mycobacterium tuberculosis H37Rv.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Quinolines | 2001 |
Profiles of hepatic and dysrhythmic cardiovascular events following use of fluoroquinolone antibacterials: experience from large cohorts from the Drug Safety Research Unit Prescription-Event Monitoring database.
Topics: Adult; Aged; Anti-Infective Agents; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Ciprofloxacin; Cohort Studies; Databases, Factual; Drug Monitoring; England; Enoxacin; Family Practice; Female; Humans; Liver Diseases; Male; Middle Aged; Norfloxacin; Ofloxacin; Product Surveillance, Postmarketing; Retrospective Studies; Surveys and Questionnaires; Time Factors | 2001 |
[Activity of new fluoroquinolones against clinical isolates of Acinetobacter baumannii].
Topics: Acinetobacter; Acinetobacter Infections; Ampicillin; Anti-Infective Agents; Aza Compounds; Cefepime; Cephalosporins; Ciprofloxacin; Colistin; Fluoroquinolones; Gatifloxacin; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Moxifloxacin; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Opportunistic Infections; Quinolines; Sulbactam; Thienamycins | 2001 |
[In vitro activity of six fluoroquinolones and penicillin against 101 viridans group streptococci characterized by their susceptibility to erythromycin].
Topics: Anti-Infective Agents; Aza Compounds; Bacteremia; Ciprofloxacin; Drug Resistance; Drug Resistance, Multiple, Bacterial; Erythromycin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Norfloxacin; Ofloxacin; Penicillins; Quinolines; Streptococcal Infections; Streptococcus | 2001 |
Resistance of Klebsiella pneumoniae strains producing and not producing ESBL (extended-spectrum beta-lactamase) type enzymes to selected non-beta-lactam antibiotics.
Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactamases; Ciprofloxacin; Drug Resistance, Microbial; Gentamicins; Klebsiella pneumoniae; Microbial Sensitivity Tests; Nalidixic Acid; Netilmicin; Norfloxacin; Prevalence; Time Factors | 2002 |
Effectiveness of 3 vs. 7 day therapy cited.
Topics: Anti-Infective Agents; Ciprofloxacin; Cystitis; Drug Administration Schedule; Female; Humans; Norfloxacin; Randomized Controlled Trials as Topic; Trimethoprim, Sulfamethoxazole Drug Combination | 2001 |
Osteoadsorptive bisphosphonate derivatives of fluoroquinolone antibacterials.
Topics: Animals; Anti-Infective Agents; Bone and Bones; Ciprofloxacin; Diphosphonates; Enoxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydrogen-Ion Concentration; In Vitro Techniques; Microbial Sensitivity Tests; Norfloxacin; Piperazines; Quinolones; Rats; Spectrometry, Fluorescence; Structure-Activity Relationship; Swine | 2002 |
Clinical toxicological aspects of fluoroquinolones.
Topics: Anti-Infective Agents; Bacterial Infections; Cardiovascular Diseases; Central Nervous System Diseases; Ciprofloxacin; Connective Tissue Diseases; Diarrhea; Dizziness; Gastrointestinal Diseases; Headache; Humans; Nausea; Norfloxacin; Ofloxacin; Vomiting | 2002 |
Antibiotic susceptibility pattern of Salmonella worthington isolated from neonates--a retrospective study.
Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Cefotaxime; Chloramphenicol; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Humans; Infant, Newborn; Infant, Newborn, Diseases; Meningitis; Norfloxacin; Penicillins; Prevalence; Retrospective Studies; Salmonella; Salmonella Infections; Sepsis; Time Factors | 2002 |
[Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration].
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; beta-Alanine; Biphenyl Compounds; Cefazolin; Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Convulsants; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Imipenem; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Norfloxacin; Oxazines; Penicillin G; Quinolones; Seizures; Thienamycins | 2002 |
Comparative articular toxicity of garenoxacin, a novel quinolone antimicrobial agent, in juvenile beagle dogs.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Cartilage, Articular; Ciprofloxacin; Dogs; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Indoles; Injections, Intravenous; Joint Diseases; Male; Norfloxacin; Quinolones; Toxicity Tests | 2002 |
Release kinetics and up-take studies of model fluoroquinolones from carbomer hydrogels.
Topics: Acrylic Resins; Animals; Anti-Infective Agents; Ciprofloxacin; Colloids; Colony Count, Microbial; Drug Carriers; Drug Incompatibility; Drug Stability; Escherichia coli; Hydrogels; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Male; Microbial Sensitivity Tests; Norfloxacin; Polyvinyls; Rats; Staphylococcus aureus; Water | 2002 |
Environmental exposure and risk assessment of fluoroquinolone antibacterial agents in wastewater and river water of the Glatt Valley Watershed, Switzerland.
Topics: Anti-Infective Agents; Chlorophyta; Ciprofloxacin; Drug Industry; Environmental Exposure; Fresh Water; Norfloxacin; Pseudomonas putida; Quality Control; Risk Assessment; Switzerland; Water Pollutants, Chemical; Water Purification; Water Supply | 2002 |
Determination of fluoroquinolone antibacterial agents in sewage sludge and sludge-treated soil using accelerated solvent extraction followed by solid-phase extraction.
Topics: Anti-Infective Agents; Chemistry Techniques, Analytical; Chemistry, Physical; Ciprofloxacin; Humans; Medical Waste; Norfloxacin; Reproducibility of Results; Sensitivity and Specificity; Sewage; Soil Pollutants; Solvents | 2002 |
The NorM efflux pump of Neisseria gonorrhoeae and Neisseria meningitidis recognizes antimicrobial cationic compounds.
Topics: Amino Acid Sequence; Antiporters; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Molecular Sequence Data; Mutation; Neisseria gonorrhoeae; Neisseria meningitidis; Norfloxacin; Structure-Activity Relationship; Transcription, Genetic | 2003 |
Quinolone susceptibility of Vibrio cholerae O1 & O139 isolates from Vellore.
Topics: Anti-Infective Agents; Ciprofloxacin; Humans; India; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Vibrio cholerae O1; Vibrio cholerae O139 | 2002 |
[Comparative in vitro activities of several antimicrobial agents against Helicobacter pylori].
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Ciprofloxacin; Clarithromycin; Drug Resistance, Bacterial; Erythromycin; Fluoroquinolones; Gastric Mucosa; Helicobacter pylori; Humans; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Penicillins; Stomach Ulcer | 2002 |
Reliability of phototoxic tests of fluoroquinolones in vitro.
Topics: 3T3 Cells; Animals; Anti-Infective Agents; Ciprofloxacin; Cricetinae; Cricetulus; Dermatitis, Phototoxic; Female; Fluoroquinolones; Mice; Mice, Inbred BALB C; Micronucleus Tests; Norfloxacin; Quinolones; Rats; Rats, Wistar; Ultraviolet Rays | 2003 |
Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cell Membrane Permeability; Ciprofloxacin; HeLa Cells; Humans; Lysosomes; Membrane Proteins; Metalloendopeptidases; Mitochondria; Norfloxacin; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2003 |
Low levels of fluoroquinolone resistance in Escherichia coli. A five-year trend in Australia measured through the use of TSN Database Australia.
Topics: Australia; Ciprofloxacin; Databases, Factual; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Humans; Norfloxacin; Population Surveillance; Time Factors | 2003 |
Simultaneous measurement of fluoroquinolones in eggs by a combination of supercritical fluid extraction and high pressure liquid chromatography.
Topics: Anti-Bacterial Agents; Calibration; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Ciprofloxacin; Eggs; Enrofloxacin; Fluoroquinolones; Food Contamination; Norfloxacin; Ofloxacin; Quinolones; Solvents | 2003 |
[In vitro fluoroquinolone resistance in ocular bacterial isolates].
Topics: Actinomyces; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Eye; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Norfloxacin; Ofloxacin | 2003 |
[Synthesis and antibacterial activity of pyridonecarboxylic acid derivatives containing 2-methyl-5-nitroimidazol].
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Combinatorial Chemistry Techniques; Enoxacin; Escherichia coli; Female; Mice; Microbial Sensitivity Tests; Molecular Structure; Nitroimidazoles; Norfloxacin | 2003 |
[Synthesis and antibacterial activity of 7-(4-acylamino-thiocarbamoyl-1-piperazinyl) fluoroquinolone analogues in vitro].
Topics: Anti-Infective Agents; Bacillus subtilis; Ciprofloxacin; Combinatorial Chemistry Techniques; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Molecular Structure; Norfloxacin | 2003 |
[Studies on correlation between protonation and tautomerism and luminescence characteristics of quinolone].
Topics: Anti-Infective Agents; Chemical Phenomena; Chemistry, Physical; Ciprofloxacin; Energy Transfer; Fluoroquinolones; Hydrogen-Ion Concentration; Luminescence; Molecular Structure; Norfloxacin; Piperazines; Protons; Quinolones; Spectrometry, Fluorescence; Stereoisomerism; Structure-Activity Relationship | 2001 |
Binding characteristics of fluoroquinolones to synthetic levodopa melanin.
Topics: Binding Sites; Chloroquine; Ciprofloxacin; Drug Interactions; Enoxacin; Fluoroquinolones; Levodopa; Levofloxacin; Melanins; Monophenol Monooxygenase; Norfloxacin; Ofloxacin; Quinolones; Timolol | 2003 |
Mutation rate and evolution of fluoroquinolone resistance in Escherichia coli isolates from patients with urinary tract infections.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; Norfloxacin; Urinary Tract Infections | 2003 |
Synthesis and in vitro antibacterial evaluation of N-[5-(5-nitro-2-thienyl)-1,3,4-thiadiazole-2-yl] piperazinyl quinolones.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Enoxacin; Microbial Sensitivity Tests; Norfloxacin; Piperazine; Piperazines; Quinolones | 2003 |
[Do tendon lesions occur during quinolone administration?].
Topics: Achilles Tendon; Adult; Age Factors; Anti-Infective Agents; Bronchitis; Ciprofloxacin; Enzyme Inhibitors; Fluoroquinolones; Humans; Incidence; Male; Norfloxacin; Ofloxacin; Risk Factors; Rupture; Time Factors | 2003 |
Corneal and scleral permeability of quinolones--a pharmacokinetics study.
Topics: Administration, Topical; Animals; Aqueous Humor; Cell Membrane Permeability; Cinoxacin; Ciprofloxacin; Conjunctiva; Cornea; Enoxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones; Rabbits; Sclera; Time Factors; Water | 2003 |
[Pharmacoeconomic evaluation of use of ciprofloxacin and norfloxacin with cost-benefit analysis].
Topics: Adult; Anti-Infective Agents; Bosnia and Herzegovina; Ciprofloxacin; Cost-Benefit Analysis; Humans; Norfloxacin; Urinary Tract Infections | 2003 |
Atomic absorption spectroscopic, conductometric and colorimetric methods for determination of fluoroquinolone antibiotics using ammonium reineckate ion-pair complex formation.
Topics: Absorption; Acetone; Anti-Bacterial Agents; Ciprofloxacin; Colorimetry; Dose-Response Relationship, Drug; Electric Conductivity; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Ions; Linear Models; Norfloxacin; Ofloxacin; Quaternary Ammonium Compounds; Quinolones; Salts; Solvents; Spectrophotometry, Atomic; Thiocyanates | 2004 |
[Study on the molecular mechanism of quinolone resistance in Shigellae spp].
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pipemidic Acid; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Quinolones; Shigella | 2004 |
Diabetes mellitus in itself is not a risk factor for antibiotic resistance in Escherichia coli isolated from patients with bacteriuria.
Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Infective Agents; Bacteriuria; Ciprofloxacin; Diabetes Complications; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Humans; Middle Aged; Nitrofurantoin; Norfloxacin; Ofloxacin; Risk Factors; Trimethoprim, Sulfamethoxazole Drug Combination | 2004 |
Generating signals of drug-adverse effects from prescription databases and application to the risk of arrhythmia associated with antibacterials.
Topics: Adverse Drug Reaction Reporting Systems; Anti-Bacterial Agents; Arrhythmias, Cardiac; Case-Control Studies; Ciprofloxacin; Clarithromycin; Cohort Studies; Community Health Planning; Databases, Factual; Drug Monitoring; Erythromycin; Humans; Italy; Levofloxacin; Miocamycin; Norfloxacin; Ofloxacin; Pharmacoepidemiology; Risk Factors | 2005 |
Spectrophotometric determination of some fluoroquinolone antibacterials by binary complex formation with xanthene dyes.
Topics: Anti-Infective Agents; Ciprofloxacin; Eosine Yellowish-(YS); Levofloxacin; Merbromin; Norfloxacin; Ofloxacin; Spectrophotometry, Ultraviolet; Tablets | 2004 |
An unusually high level of quinolone resistance associated with type II topoisomerase mutations in quinolone resistance-determining regions of Aeromonas caviae isolated from diarrhoeal patients.
Topics: Aeromonas; Anti-Infective Agents; Base Sequence; Ciprofloxacin; Diarrhea; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Norfloxacin | 2004 |
A comparison of effects of fluoroquinolones on fracture healing (an experimental study in rats).
Topics: Animals; Ciprofloxacin; Femoral Fractures; Fluoroquinolones; Fracture Healing; Norfloxacin; Ofloxacin; Pefloxacin; Rats; Rats, Wistar | 2005 |
Vibrational spectroscopic characterization of fluoroquinolones.
Topics: Aza Compounds; Cinoxacin; Ciprofloxacin; DNA Gyrase; DNA, Bacterial; Enoxacin; Enzyme Inhibitors; Fluoroquinolones; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Chemical; Models, Molecular; Models, Theoretical; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxolinic Acid; Quinolines; Quinolones; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Temperature; Ultraviolet Rays; Vibration; Water | 2005 |
The simultaneous separation and determination of five quinolone antibiotics using isocratic reversed-phase HPLC: application to stability studies on an ofloxacin tablet formulation.
Topics: Anti-Bacterial Agents; Calibration; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Industry; Drug Stability; Fluoroquinolones; Hydrogen-Ion Concentration; Models, Chemical; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones; Reproducibility of Results; Tablets; Time Factors | 2005 |
Ciprofloxacin and norfloxacin pharmacokinetics and prostatic fluid penetration in dogs after multiple oral dosing.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dogs; Male; Norfloxacin; Prostate | 2006 |
HPLC determination of enoxacin, ciprofloxacin, norfloxacin and ofloxacin with photoinduced fluorimetric (PIF) detection and multiemission scanning: application to urine and serum.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Norfloxacin; Ofloxacin; Sensitivity and Specificity; Spectrometry, Fluorescence | 2005 |
Inhibition of cell differentiation by quinolones in micromass cultures of rat embryonic limb bud and midbrain cells.
Topics: Animals; Anti-Infective Agents; Cell Differentiation; Cell Proliferation; Cell Survival; Ciprofloxacin; Dose-Response Relationship, Drug; Embryo Culture Techniques; Enrofloxacin; Fluoroquinolones; Inhibitory Concentration 50; Limb Buds; Mesencephalon; Norfloxacin; Quinolones; Rats; Rats, Wistar | 2005 |
Fluoroquinolone-resistant Vibrio cholerae isolated during a cholera outbreak in India.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Child; Child, Preschool; Cholera; Ciprofloxacin; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; India; Middle Aged; Norfloxacin; Vibrio cholerae | 2006 |
Interactions between 4-quinolone antibacterials and multivalent metal ions.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Gram-Negative Bacteria; Metals; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones | 1989 |
Inhibitory effect of several fluoroquinolones on hepatic microsomal cytochrome P-450 1A activities in dogs.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Cytochrome P-450 CYP1A1; Dogs; Drug Interactions; Enrofloxacin; Fluoroquinolones; Male; Microsomes, Liver; Norfloxacin; Ofloxacin | 2005 |
T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antigen-Presenting Cells; Aza Compounds; Cell Proliferation; Cells, Cultured; Ciprofloxacin; Clone Cells; Cross Reactions; Drug Hypersensitivity; Enoxacin; Female; Fluoroquinolones; Humans; Hypersensitivity, Delayed; Middle Aged; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Patch Tests; Pipemidic Acid; Quinolines; Quinolones; T-Lymphocytes | 2006 |
Sensitive determination of ciprofloxacin and norfloxacin in biological fluids using an enzymatic rotating biosensor.
Topics: Biosensing Techniques; Body Fluids; Ciprofloxacin; Enzymes; Humans; Norfloxacin | 2006 |
Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Availability; Cell Line; Ciprofloxacin; Dogs; Female; Fluoroquinolones; Lactation; Male; Mice; Mice, Knockout; Milk; Neoplasm Proteins; Norfloxacin; Ofloxacin; Transfection | 2006 |
Involvement of the putative ATP-dependent efflux proteins PatA and PatB in fluoroquinolone resistance of a multidrug-resistant mutant of Streptococcus pneumoniae.
Topics: Anti-Infective Agents; ATP-Binding Cassette Transporters; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Norfloxacin; Phenotype; Reserpine; RNA, Messenger; Streptococcus pneumoniae | 2006 |
Susceptibility studies of piperazinyl-cross-linked fluoroquinolone dimers against test strains of Gram-positive and Gram-negative bacteria.
Topics: Ciprofloxacin; Dimerization; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Norfloxacin | 2006 |
Selective action of fluoroquinolones against intracellular amastigotes of Leishmania (Viannia) panamensis in vitro.
Topics: Animals; Cell Line; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Leishmania guyanensis; Macrophages; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones | 2005 |
Liver initiation activity of norfloxacin but not nalidixic acid, pipemidic acid, and ciprofloxacin on in vivo short-term liver initiation assay in rats.
Topics: 2-Acetylaminofluorene; Animals; Anti-Infective Agents; Carbon Tetrachloride; Carcinogens; Ciprofloxacin; Glutathione Transferase; Liver; Male; Nalidixic Acid; Norfloxacin; Pipemidic Acid; Rats; Rats, Inbred F344 | 2006 |
Transfection of drug-specific T-cell receptors into hybridoma cells: tools to monitor drug interaction with T-cell receptors and evaluate cross-reactivity to related compounds.
Topics: Animals; B-Lymphocytes; CD3 Complex; CD4 Antigens; Cell Line, Transformed; Cells, Cultured; Ciprofloxacin; Cross Reactions; Drug Interactions; Flow Cytometry; Humans; Hybridomas; Interleukin-2; Mice; Norfloxacin; Quinolones; Receptors, Antigen, T-Cell; Sulfamethizole; Sulfamethoxazole; Sulfanilamides; T-Lymphocytes; Time Factors; Transfection | 2006 |
A new approach to quantitative NMR: fluoroquinolones analysis by evaluating the chemical shift displacements.
Topics: Anti-Infective Agents; Ciprofloxacin; Electromagnetic Fields; Enoxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Norfloxacin; Protons; Reproducibility of Results; Solutions; Temperature | 2006 |
Antibacterial evaluation of a collection of norfloxacin and ciprofloxacin derivatives against multiresistant bacteria.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Microbial Sensitivity Tests; Norfloxacin | 2006 |
Urinary bactericidal activity of oral antibiotics against common urinary tract pathogens in an ex vivo model.
Topics: Acetamides; Administration, Oral; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; beta-Lactamases; Biomarkers; Cefadroxil; Ceftibuten; Cefuroxime; Cephalexin; Cephalosporins; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Middle Aged; Norfloxacin; Oxazolidinones; Time Factors; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections | 2006 |
Adsorption and oxidation of fluoroquinolone antibacterial agents and structurally related amines with goethite.
Topics: Absorption; Anti-Bacterial Agents; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Iron Compounds; Kinetics; Minerals; Molecular Structure; Norfloxacin; Ofloxacin; Oxidation-Reduction | 2007 |
Determination of ofloxacin, norfloxacin, and ciprofloxacin in sewage by selective solid-phase extraction, liquid chromatography with fluorescence detection, and liquid chromatography--tandem mass spectrometry.
Topics: Chromatography, Liquid; Ciprofloxacin; Fluorescence; Molecular Structure; Norfloxacin; Ofloxacin; Reproducibility of Results; Sewage; Solid Phase Extraction; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2007 |
Environmental risk assessment of antibiotics in the Swedish environment with emphasis on sewage treatment plants.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Environmental Monitoring; Fluoroquinolones; Geography; Norfloxacin; Sewage; Sweden; Waste Disposal, Fluid; Water Pollution, Chemical | 2007 |
Antacid interaction with new quinolones: dose regimen recommendations based on pharmacokinetic modeling of clinical data for ciprofloxacin, gatifloxacin and norfloxacin and metal cations.
Topics: Administration, Oral; Aluminum Hydroxide; Antacids; Anti-Infective Agents; Biological Availability; Cations; Ciprofloxacin; Drug Administration Schedule; Drug Combinations; Drug Interactions; Fluoroquinolones; Gatifloxacin; Humans; Intestinal Absorption; Magnesium Hydroxide; Models, Biological; Norfloxacin; Reference Values; Sucralfate | 2007 |
Development of a monoclonal antibody-based broad-specificity ELISA for fluoroquinolone antibiotics in foods and molecular modeling studies of cross-reactive compounds.
Topics: Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibody Specificity; Ciprofloxacin; Enrofloxacin; Enzyme-Linked Immunosorbent Assay; Fluoroquinolones; Food Contamination; Inhibitory Concentration 50; Norfloxacin; Ofloxacin; Quantitative Structure-Activity Relationship; Sensitivity and Specificity | 2007 |
Resolution of ofloxacin-ciprofloxacin and ofloxacin-norfloxacin binary mixtures by flow-injection chemiluminescence in combination with partial least squares multivariate calibration.
Topics: Anti-Infective Agents; Cerium; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Combinations; Flow Injection Analysis; Least-Squares Analysis; Luminescent Measurements; Multivariate Analysis; Norfloxacin; Ofloxacin; Organometallic Compounds; Sulfuric Acids | 2007 |
Monitoring of fluoroquinolone residual levels in chicken eggs by microbiological assay and confirmation by liquid chromatography.
Topics: Animals; Anti-Bacterial Agents; Biological Assay; Calibration; Chemical Fractionation; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Residues; Eggs; Enrofloxacin; Escherichia coli; Fluoroquinolones; Food Analysis; Food Contamination; Mass Spectrometry; Norfloxacin; Sensitivity and Specificity; Spectrometry, Fluorescence | 2008 |
NMR and IR characterization of the aluminium complexes of norfloxacin and ciprofloxacin fluoroquinolones.
Topics: Aluminum Compounds; Carbon; Ciprofloxacin; Magnetic Resonance Spectroscopy; Molecular Structure; Norfloxacin; Spectrophotometry, Infrared; Time Factors | 2007 |
[Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry].
Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2007 |
[Simultaneous determination of residues of three fluoroquinolones in chicken using high performance liquid chromatography with post-column derivatization and terbium sensitized fluorescence].
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Reproducibility of Results; Terbium | 2007 |
Anxiogenic potential of ciprofloxacin and norfloxacin in rats.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anxiety; Ciprofloxacin; Exploratory Behavior; Fear; Feeding Behavior; Female; Male; Maze Learning; Norfloxacin; Rats; Social Behavior; Social Environment | 2007 |
Monohydrous dihydrogen phosphate salts of norfloxacin and ciprofloxacin.
Topics: Anions; Ciprofloxacin; Crystallization; Crystallography, X-Ray; Hydrogen Bonding; Molecular Structure; Norfloxacin; Phosphoric Acids; Solutions; Water | 2007 |
Quinolone-resistant Escherichia coli.
Topics: Anti-Infective Agents; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; Drug Resistance, Bacterial; Escherichia coli; Female; Genes, Bacterial; Humans; Male; Mutation; Nalidixic Acid; Norfloxacin | 2008 |
Comparison of solid-phase sorbents for the determination of fluoroquinolone antibiotics in wastewater.
Topics: Adsorption; Anti-Bacterial Agents; Cation Exchange Resins; Chromatography, High Pressure Liquid; Ciprofloxacin; Edetic Acid; Enrofloxacin; Fluoroquinolones; Hydrophobic and Hydrophilic Interactions; Norfloxacin; Ofloxacin; Polymers; Reproducibility of Results; Sensitivity and Specificity; Sewage; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2008 |
Study of fluorescence characteristics of the charge-transfer reaction of quinolone agents with bromanil.
Topics: Anti-Bacterial Agents; Benzoquinones; Catalysis; Ciprofloxacin; Electrons; Energy Transfer; Models, Biological; Norfloxacin; Ofloxacin; Osmolar Concentration; Quinolones; Solvents; Spectrometry, Fluorescence; Technology, Pharmaceutical; Temperature; Time Factors | 2009 |
Formation of secondary triplet species after excitation of fluoroquinolones in the presence of relatively strong bases.
Topics: Anti-Infective Agents; Buffers; Ciprofloxacin; Enoxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Norfloxacin; Oxygen; Photolysis; Solutions; Spectrophotometry; Water | 2008 |
Posttranslational modification influences the effects of MgrA on norA expression in Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Bacterial; Mass Spectrometry; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Mutation; Norfloxacin; Promoter Regions, Genetic; Protein Binding; Protein Processing, Post-Translational; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcus aureus; Transcription, Genetic | 2008 |
Determination of quinolone antibiotics in urine by capillary electrophoresis with chemiluminescence detection.
Topics: Anti-Infective Agents; Ciprofloxacin; Electrophoresis, Capillary; Humans; Luminescent Measurements; Molecular Structure; Norfloxacin; Ofloxacin; Quinolones; Sensitivity and Specificity; Solvents | 2008 |
Synthesis and antimicrobial activity of ciprofloxacin and norfloxacin permanently bonded to polyethylene glycol by a thiourea linker.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Cross-Linking Reagents; Indicators and Reagents; Mass Spectrometry; Microbial Sensitivity Tests; Norfloxacin; Polyethylene Glycols; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Thiourea | 2009 |
Solubility behavior and biopharmaceutical classification of novel high-solubility ciprofloxacin and norfloxacin pharmaceutical derivatives.
Topics: Biopharmaceutics; Ciprofloxacin; Drug Compounding; Excipients; Norfloxacin; Permeability; Solubility; Tablets | 2009 |
Standard addition analysis of fluoroquinolones in human serum in the presence of the interferent salicylate using lanthanide-sensitized excitation-time decay luminescence data and multivariate curve resolution.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Humans; Lanthanoid Series Elements; Luminescent Measurements; Norfloxacin; Salicylates; Terbium | 2009 |
Acetylation of fluoroquinolone antimicrobial agents by an Escherichia coli strain isolated from a municipal wastewater treatment plant.
Topics: Acetylation; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Escherichia coli; Fluoroquinolones; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Norfloxacin; Waste Disposal, Fluid | 2009 |
Fluoroquinolone-resistant Brucella melitensis mutants obtained in vitro.
Topics: Anti-Bacterial Agents; Aza Compounds; Brucella melitensis; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Norfloxacin; Ofloxacin; Quinolines; Sequence Analysis, DNA | 2009 |
Studies of the photooxidant properties of antibacterial fluoroquinolones and their naphthalene derivatives.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Culture Media; Enoxacin; Escherichia coli; Fluoroquinolones; Histidine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Luminescence; Naphthalenes; Norfloxacin; Oxidants; Oxidants, Photochemical; Photolysis; Photosensitizing Agents; Reactive Oxygen Species; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Ultraviolet Rays | 2009 |
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Diclofenac; Dioxolanes; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Phenylacetates; Piperazines; Receptors, GABA-A; Seizures | 2009 |
[Multi-residue determination of 11 quinolones in chicken muscle by high performance liquid chromatography with fluorescence detection].
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Residues; Fluorescence; Norfloxacin; Ofloxacin; Poultry Products; Quinolones | 2009 |
Comparison of fluoroquinolones: cytotoxicity on human corneal epithelial cells.
Topics: Anti-Infective Agents; Aza Compounds; Cell Survival; Cells, Cultured; Ciprofloxacin; Electric Impedance; Epithelial Cells; Epithelium, Corneal; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Moxifloxacin; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Preservatives, Pharmaceutical; Quinolines | 2010 |
[Simultaneous analysis of 7 fluoroquinolone residues in chicken muscle by ultra performance liquid chromatography-electrospray ionization tandem mass spectrometry].
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Residues; Fluoroquinolones; Food Contamination; Meat; Norfloxacin; Ofloxacin; Poultry; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2009 |
Relationship between the expression of ompF and quinolone resistance in Escherichia coli.
Topics: Animals; Anti-Bacterial Agents; Cell Growth Processes; Ciprofloxacin; Disease Models, Animal; DNA Gyrase; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Gene Expression; Genetic Complementation Test; Humans; Mice; Microbial Sensitivity Tests; Mutation; Norfloxacin; Polymerase Chain Reaction; Porins | 2009 |
Phosphorylation of MgrA and its effect on expression of the NorA and NorB efflux pumps of Staphylococcus aureus.
Topics: Bacterial Proteins; Base Sequence; Ciprofloxacin; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Norfloxacin; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcus aureus | 2010 |
Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Antigens, Bacterial; Bacterial Outer Membrane Proteins; Bacterial Typing Techniques; Carrier Proteins; Child; Ciprofloxacin; Drug Resistance, Bacterial; Humans; Molecular Epidemiology; Norfloxacin; Point Mutation; Portugal; Streptococcal Infections; Streptococcus pyogenes | 2010 |
When unfolding is better: unique success of unfolded partial least-squares regression with residual bilinearization for the processing of spectral-pH data with strong spectral overlapping. Analysis of fluoroquinolones in human urine based on flow-injectio
Topics: Algorithms; Anti-Bacterial Agents; Ciprofloxacin; Clinical Laboratory Techniques; Factor Analysis, Statistical; Flow Injection Analysis; Fluorescence; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Least-Squares Analysis; Norfloxacin; Nucleic Acid Denaturation; Spectrometry, Fluorescence | 2009 |
Competitive sorption and desorption behavior for three fluoroquinolone antibiotics in a wastewater treatment wetland soil.
Topics: Absorption; Adsorption; Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Kinetics; Norfloxacin; Ofloxacin; Soil; Soil Pollutants; Waste Disposal, Fluid; Wetlands | 2010 |
Development and validation of a fast isocratic liquid chromatography method for the simultaneous determination of norfloxacin, lomefloxacin and ciprofloxacin in human plasma.
Topics: Anti-Infective Agents; Chromatography, Liquid; Ciprofloxacin; Drug Stability; Fluoroquinolones; Humans; Levofloxacin; Linear Models; Norfloxacin; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity | 2011 |
Inequality in quality? Regional and educational differences in treatment with fluoroquinolone in urinary tract infection of 236,376 Swedish patients.
Topics: Adolescent; Adult; Age Distribution; Amdinocillin Pivoxil; Anti-Infective Agents, Urinary; Ciprofloxacin; Drug Utilization; Female; Fluoroquinolones; Guideline Adherence; Healthcare Disparities; Humans; Middle Aged; Multivariate Analysis; Nitrofurantoin; Norfloxacin; Practice Patterns, Physicians'; Quality Indicators, Health Care; Risk Adjustment; Social Class; Sweden; Trimethoprim; Urinary Tract Infections | 2011 |
[Preliminary study on occurrence and health risk assessment of quinolone antibiotics in vegetables from Guangzhou, China].
Topics: Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Food Contamination; Norfloxacin; Quinolones; Risk Assessment; Urban Health; Vegetables | 2010 |
Selective intestinal decontamination with fluoroquinolones for the prevention of early bacterial infections after liver transplantation.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Female; Fluoroquinolones; Hematopoietic Stem Cells; Humans; Intestines; Liver Failure; Liver Transplantation; Male; Middle Aged; Multivariate Analysis; Norfloxacin; Organ Transplantation; Prospective Studies; Registries; Spain; Treatment Outcome | 2011 |
Fluoroquinolone salts with carboxylic acids.
Topics: Anti-Bacterial Agents; Calorimetry, Differential Scanning; Carboxylic Acids; Ciprofloxacin; Crystallization; Drug Discovery; Drug Stability; Hydrogen Bonding; Models, Molecular; Molecular Structure; Norfloxacin; Salts; Solubility; Spectrophotometry, Infrared; X-Ray Diffraction | 2011 |
Antibacterial effects of Brazilian and Bulgarian propolis and synergistic effects with antibiotics acting on the bacterial DNA and folic acid.
Topics: Anti-Bacterial Agents; Brazil; Bulgaria; Ciprofloxacin; DNA, Bacterial; Drug Synergism; Folic Acid; Microbial Sensitivity Tests; Norfloxacin; Propolis; Salmonella typhi; Trimethoprim, Sulfamethoxazole Drug Combination | 2012 |
Chemiluminescence determination of fluoroquinolones using Fenton system in the presence of terbium(iii) ions.
Topics: Ciprofloxacin; Fluoroquinolones; Hydrogen Peroxide; Ions; Iron; Luminescent Measurements; Norfloxacin; Ofloxacin; Pharmaceutical Preparations; Spectrometry, Fluorescence; Terbium | 2011 |
In vitro potentiation of ampicillin, oxacillin, norfloxacin, ciprofloxacin, and vancomycin by sanguinarine against methicillin-resistant Staphylococcus aureus.
Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Load; Benzophenanthridines; Ciprofloxacin; Drug Synergism; Drug Therapy, Combination; Isoquinolines; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Norfloxacin; Oxacillin; Species Specificity; Vancomycin | 2011 |
Oral toxicity of pefloxacin, norfloxacin, ofloxacin and ciprofloxacin: comparison of biomechanical and histopathological effects on Achilles tendon in rats.
Topics: Achilles Tendon; Administration, Oral; Animals; Anti-Bacterial Agents; Ciprofloxacin; Elastic Modulus; Elasticity; Fluoroquinolones; Male; Norfloxacin; Ofloxacin; Pefloxacin; Rats; Rats, Wistar; Tensile Strength | 2011 |
Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS.
Topics: Amoxicillin; Anti-Bacterial Agents; Chromatography, Liquid; Ciprofloxacin; Erythromycin; Fluoroquinolones; Hydrogen-Ion Concentration; Norfloxacin; Ofloxacin; Oxolinic Acid; Reproducibility of Results; Rivers; Solid Phase Extraction; Sulfamethoxazole; Tandem Mass Spectrometry; Tetracycline; Trimethoprim; Tylosin; Vancomycin; Water Pollutants, Chemical | 2011 |
Residues of fluoroquinolones in marine aquaculture environment of the Pearl River Delta, South China.
Topics: Animals; Anti-Infective Agents; China; Chromatography, High Pressure Liquid; Ciprofloxacin; Environmental Monitoring; Geologic Sediments; Humans; Limit of Detection; Norfloxacin; Perciformes; Risk Assessment; Seawater; Species Specificity; Water Pollutants, Chemical | 2012 |
Two fluoroalcohols as components of basic buffers for liquid chromatography electrospray ionization mass spectrometric determination of antibiotic residues.
Topics: Anti-Bacterial Agents; Chromatography, Liquid; Ciprofloxacin; Drug Residues; Lactuca; Mass Spectrometry; Norfloxacin; Ofloxacin; Propanols; Spectrometry, Mass, Electrospray Ionization; Sulfadimethoxine; Sulfamethoxazole | 2011 |
Degradation of the antibiotics norfloxacin and ciprofloxacin by a white-rot fungus and identification of degradation products.
Topics: Anti-Bacterial Agents; Biodegradation, Environmental; Biotechnology; Biotransformation; Chromatography, Liquid; Ciprofloxacin; Dimerization; Laccase; Mass Spectrometry; Models, Chemical; Norfloxacin; Oxygen; Tandem Mass Spectrometry; Technology, Pharmaceutical; Time Factors; Trametes; Triazoles | 2011 |
Grafting of norfloxacin imprinted polymeric membranes on silica surface for the selective solid-phase extraction of fluoroquinolones in fish samples.
Topics: Adsorption; Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Fishes; Limit of Detection; Membranes, Artificial; Methacrylates; Molecular Imprinting; Norfloxacin; Ofloxacin; Polymers; Porosity; Silanes; Silica Gel; Solid Phase Extraction; Solvents; Vinyl Compounds | 2012 |
Detection of antibacterial-like activity on a silica surface: fluoroquinolones and their environmental metabolites.
Topics: Anti-Bacterial Agents; Bacteria; Bacteriological Techniques; Ciprofloxacin; Drug Resistance, Bacterial; Enrofloxacin; Environmental Monitoring; Fluoroquinolones; Norfloxacin; Silicon Dioxide; Soil; Soil Pollutants | 2011 |
Development of a dispersive liquid-liquid microextraction method for the determination of fluoroquinolones in chicken liver by high performance liquid chromatography.
Topics: Animals; Anti-Bacterial Agents; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Limit of Detection; Liquid Phase Microextraction; Liver; Norfloxacin; Regression Analysis; South Africa | 2012 |
Aluminium sensitized spectrofluorimetric determination of fluoroquinolones in milk samples coupled with salting-out assisted liquid-liquid ultrasonic extraction.
Topics: Acetonitriles; Aluminum; Ammonium Sulfate; Animals; Cattle; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Hydrogen-Ion Concentration; Limit of Detection; Liquid-Liquid Extraction; Milk; Norfloxacin; Ofloxacin; Solutions; Spectrometry, Fluorescence; Temperature; Ultrasonics; Water | 2012 |
Occurrence and sorption of fluoroquinolones in poultry litters and soils from São Paulo State, Brazil.
Topics: Animals; Anti-Bacterial Agents; Brazil; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Floors and Floorcoverings; Fluorescence; Fluoroquinolones; Housing, Animal; Norfloxacin; Poultry; Soil Pollutants | 2012 |
Spectroscopic study of degradation products of ciprofloxacin, norfloxacin and lomefloxacin formed in ozonated wastewater.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Mass Spectrometry; Norfloxacin; Oxidation-Reduction; Ozone; Piperazine; Piperazines; Quinolones; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2012 |
Transport studies through liquid membranes of ciprofloxacin and norfloxacin.
Topics: Anti-Bacterial Agents; Biochemistry; Biological Transport; Ciprofloxacin; Equipment Design; Glucose; Ions; Micelles; Norfloxacin; Nucleic Acid Synthesis Inhibitors; Permeability; Surface-Active Agents; Water | 2004 |
[Prevalence of qnr genes in clinical Enterobacteriaceae non-susceptible to fluoroquinolone in Poland].
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Bacterial; Enterobacteriaceae; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Gene Frequency; Genes, Bacterial; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Poland; Species Specificity | 2012 |
Photolytic degradation of norfloxacin, enrofloxacin and ciprofloxacin in various aqueous media.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Environmental Monitoring; Fluoroquinolones; Kinetics; Norfloxacin; Photolysis; Rivers; Sunlight; Tandem Mass Spectrometry; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2013 |
A preliminary study on the phytoremediation of antibiotic contaminated sediment.
Topics: Actinomycetales; Anti-Bacterial Agents; Biodegradation, Environmental; Biological Transport; Caulobacteraceae; Ciprofloxacin; DNA, Bacterial; DNA, Ribosomal; Drug Resistance; Geologic Sediments; Half-Life; Microbial Sensitivity Tests; Norfloxacin; Plant Leaves; Plant Roots; Plant Stems; Pteridaceae; Rhizophoraceae; Vietnam; Water; Wetlands | 2013 |
Synergistic antibacterial effect of curcumin against methicillin-resistant Staphylococcus aureus.
Topics: Ampicillin; Anti-Bacterial Agents; Ciprofloxacin; Curcuma; Curcumin; Drug Synergism; Humans; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Norfloxacin; Oxacillin; Plant Extracts; Rhizome; Time Factors | 2013 |
Effect of pH on the in vitro susceptibility of planktonic and biofilm-grown Proteus mirabilis to the quinolone antimicrobials.
Topics: Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Plankton; Proteus mirabilis; Quinolones | 2013 |
Effect of subinhibitory concentrations of fluoroquinolones on biofilm production by clinical isolates of Streptococcus pyogenes.
Topics: Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Microscopy, Confocal; Microscopy, Electron, Scanning; Norfloxacin; Ofloxacin; Streptococcal Infections; Streptococcus pyogenes; Virulence | 2013 |
Effect of fluoroquinolone resistance selection on the fitness of three strains of Clostridium perfringens.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Clostridium perfringens; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Genetic Fitness; Microbial Sensitivity Tests; Microbial Viability; Mutation; Norfloxacin | 2013 |
Investigation of residual fluoroquinolones in a soil-vegetable system in an intensive vegetable cultivation area in Northern China.
Topics: Agriculture; Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Soil Pollutants; Statistics, Nonparametric; Tandem Mass Spectrometry; Vegetables | 2014 |
Biodegradation of ofloxacin, norfloxacin, and ciprofloxacin as single and mixed substrates by Labrys portucalensis F11.
Topics: Alphaproteobacteria; Anti-Bacterial Agents; Biotransformation; Carbon; Chromatography, Liquid; Ciprofloxacin; Culture Media; Environmental Pollutants; Fluorides; Humans; Mass Spectrometry; Metabolic Networks and Pathways; Norfloxacin; Ofloxacin | 2014 |
Performance of aerobic granular sludge in a sequencing batch bioreactor exposed to ofloxacin, norfloxacin and ciprofloxacin.
Topics: Aerobiosis; Bacteria; Batch Cell Culture Techniques; Biological Oxygen Demand Analysis; Bioreactors; Ciprofloxacin; Cluster Analysis; Denaturing Gradient Gel Electrophoresis; Nitrogen; Norfloxacin; Ofloxacin; Phosphates; Phylogeny; RNA, Ribosomal, 16S; Sewage | 2014 |
Degradation of fluoroquinolone antibiotics and identification of metabolites/transformation products by liquid chromatography-tandem mass spectrometry.
Topics: Anti-Bacterial Agents; Aza Compounds; Biotransformation; Chromatography, Liquid; Ciprofloxacin; Fluoroquinolones; Moxifloxacin; Norfloxacin; Ofloxacin; Photolysis; Quinolines; Tandem Mass Spectrometry | 2014 |
Determination of five quinolone antibiotic residues in foods by micellar electrokinetic capillary chromatography with quantum dot indirect laser-induced fluorescence.
Topics: Animal Feed; Animals; Anti-Bacterial Agents; Cadmium Compounds; Chromatography, Micellar Electrokinetic Capillary; Ciprofloxacin; Enrofloxacin; European Union; Fluorescence; Fluoroquinolones; Hydrogen-Ion Concentration; Japan; Lasers; Limit of Detection; Loxapine; Norfloxacin; Quantum Dots; Quinolones; Spectrometry, Fluorescence; Tellurium | 2014 |
[Simultaneous determination of clopidol, sulfonamide and quinolone residues in chickens by ultra performance liquid chromatography-tandem mass spectrometry].
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Clopidol; Drug Residues; Enrofloxacin; Fluoroquinolones; Food Contamination; Hexanes; Meat; Norfloxacin; Ofloxacin; Quinolones; Sulfanilamide; Sulfanilamides; Sulfonamides; Tandem Mass Spectrometry | 2013 |
Novel organic salts based on fluoroquinolone drugs: synthesis, bioavailability and toxicological profiles.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Biological Availability; Caco-2 Cells; Cell Survival; Chemistry, Pharmaceutical; Ciprofloxacin; Gluconates; Glycolates; Humans; Intestinal Absorption; Intestinal Mucosa; Mesylates; Micelles; Norfloxacin; Phosphorylcholine; Solubility; Solvents; Technology, Pharmaceutical; Water | 2014 |
Analysis of quinolone antibiotics in eggs: preparation and characterization of a raw material for method validation and quality control.
Topics: Anti-Bacterial Agents; Chromatography, Liquid; Ciprofloxacin; Eggs; Enrofloxacin; Fluoroquinolones; Food Contamination; Norfloxacin; Oxolinic Acid; Quality Control; Quinolones; Reproducibility of Results | 2012 |
[Antibiotic resistance and siderophore production in enterococci].
Topics: Ciprofloxacin; Drug Resistance, Bacterial; Enterococcus faecalis; Enterococcus faecium; Fluoroquinolones; Microbial Sensitivity Tests; Norfloxacin; Siderophores; Species Specificity; Virulence | 2014 |
Development of sensitive and reliable LC-MS/MS methods for the determination of three fluoroquinolones in water and fish tissue samples and preliminary environmental risk assessment of their presence in two rivers in northern Poland.
Topics: Animals; Anti-Bacterial Agents; Chromatography, Liquid; Ciprofloxacin; Enrofloxacin; Environmental Monitoring; Fishes; Fluoroquinolones; Norfloxacin; Poland; Rivers; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2014 |
Experimental and theoretical studies on the molecular properties of ciprofloxacin, norfloxacin, pefloxacin, sparfloxacin, and gatifloxacin in determining bioavailability.
Topics: Biological Availability; Buffers; Ciprofloxacin; Fluoroquinolones; Gastrointestinal Absorption; Gatifloxacin; Hydrogen-Ion Concentration; Models, Molecular; Molecular Conformation; Norfloxacin; Octanols; Pefloxacin; Phosphates; Solvents; Static Electricity; Thermodynamics | 2014 |
Responses of plasmid-mediated quinolone resistance genes and bacterial taxa to (fluoro)quinolones-containing manure in arable soil.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Enrofloxacin; Fluoroquinolones; Genes, Bacterial; Gram-Negative Bacteria; Manure; Norfloxacin; Plasmids; Quinolones; Selection, Genetic; Soil; Species Specificity; Time Factors | 2015 |
Overexpression of the novel MATE fluoroquinolone efflux pump FepA in Listeria monocytogenes is driven by inactivation of its local repressor FepR.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Listeria monocytogenes; Norfloxacin; Reserpine | 2014 |
Association of mutation patterns in GyrA and ParC genes with quinolone resistance levels in lactic acid bacteria.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Ciprofloxacin; Cultured Milk Products; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Resistance, Bacterial; Enterococcus; Lactic Acid; Lactobacillus; Microbial Sensitivity Tests; Mutation; Norfloxacin; Quinolones; Yogurt | 2015 |
Computational simulation and preparation of fluorescent magnetic molecularly imprinted silica nanospheres for ciprofloxacin or norfloxacin sensing.
Topics: Cadmium Compounds; Ciprofloxacin; Ferric Compounds; Fluorescence; Fluorescent Dyes; Humans; Magnetic Phenomena; Molecular Dynamics Simulation; Molecular Imprinting; Molecular Structure; Nanospheres; Norfloxacin; Particle Size; Polymers; Quantum Dots; Silicon Dioxide; Surface Properties; Tellurium | 2014 |
Fecal carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae in community setting in Casablanca.
Topics: Adult; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Carrier State; Ciprofloxacin; Enterobacter cloacae; Enterobacteriaceae Infections; Feces; Female; Humans; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Middle Aged; Morocco; Norfloxacin; Serratia; Young Adult | 2015 |
[Contamination characteristics of fluoroquinolones in different kinds of soil profiles in Southeast suburb of Beijing].
Topics: Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; Ciprofloxacin; Cities; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Soil; Soil Pollutants | 2014 |
Kidney function and the use of nitrofurantoin to treat urinary tract infections in older women.
Topics: Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Female; Glomerular Filtration Rate; Humans; Nitrofurantoin; Norfloxacin; Renal Insufficiency; Retrospective Studies; Sex Factors; Treatment Failure; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections | 2015 |
[Role of double strand DNA break repair for quinolone sensitivity in Escherichia coli: therapeutic implications].
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; DNA Breaks, Double-Stranded; DNA Helicases; DNA Repair; DNA Replication; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Exodeoxyribonuclease V; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Targeted Therapy; Nalidixic Acid; Norfloxacin; Quinolones; Rec A Recombinases; Recombinational DNA Repair; Serine Endopeptidases; SOS Response, Genetics | 2015 |
[Determination of 25 quinolones in cosmetics by liquid chromatography-tandem mass spectrometry].
Topics: Chromatography, Liquid; Ciprofloxacin; Cosmetics; Drug Residues; Enrofloxacin; Fluoroquinolones; Hexanes; Norfloxacin; Ofloxacin; Quinolones; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2015 |
Nonantibiotic Effects of Fluoroquinolones in Mammalian Cells.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Deferoxamine; Dioxygenases; DNA Methylation; Enrofloxacin; Epigenesis, Genetic; Fluoroquinolones; HEK293 Cells; Histones; HSP90 Heat-Shock Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Iron; Iron Chelating Agents; Methylation; Mitogen-Activated Protein Kinase 8; Molecular Structure; Norfloxacin; Reverse Transcriptase Polymerase Chain Reaction | 2015 |
Synthesis and potential antitumor activity of 7-(4-substituted piperazin-1-yl)-4-oxoquinolines based on ciprofloxacin and norfloxacin scaffolds: in silico studies.
Topics: 4-Quinolones; Antineoplastic Agents; Cell Line; Cell Proliferation; Ciprofloxacin; Computer Simulation; Humans; Molecular Structure; Norfloxacin; Piperazine; Piperazines; Structure-Activity Relationship | 2016 |
Fluoroquinolone residues in compost by green enhanced microwave-assisted extraction followed by ultra performance liquid chromatography tandem mass spectrometry.
Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Residues; Enrofloxacin; Fluoroquinolones; Microwaves; Norfloxacin; Reproducibility of Results; Soil; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2015 |
Simultaneous determination of fluoroquinolones in environmental water by liquid chromatography-tandem mass spectrometry with direct injection: A green approach.
Topics: Anti-Bacterial Agents; Brazil; Chromatography, Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Fresh Water; Gemifloxacin; Green Chemistry Technology; Moxifloxacin; Naphthyridines; Norfloxacin; Ofloxacin; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2015 |
The occurrence and removal of selected fluoroquinolones in urban drinking water treatment plants.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; China; Ciprofloxacin; Drinking Water; Enrofloxacin; Environmental Monitoring; Fluoroquinolones; Norfloxacin; Ofloxacin; Water Pollutants, Chemical; Water Purification | 2015 |
Impacts of urbanization on the prevalence of antibiotic-resistant Escherichia coli in the Chaophraya River and its tributaries.
Topics: Amoxicillin; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Drug Resistance, Microbial; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Rivers; Tetracycline; Thailand; Urbanization; Water Microbiology | 2016 |
Structural Insights into the Fluoroquinolone Resistance Mechanism of Shigella flexneri DNA Gyrase and Topoisomerase IV.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Aspartic Acid; Binding Sites; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Gene Expression; Kinetics; Microbial Sensitivity Tests; Molecular Docking Simulation; Mutation; Norfloxacin; Protein Binding; Serine; Shigella flexneri; Thermodynamics | 2016 |
MOLECULAR CHARACTERIZATION OF VIRULENCE AND ANTIMICROBIAL SUSCEPTIBILITY PROFILES OF UROPATHOGENIC ESCHERICHIA COLI FROM PATIENTS IN A TERTIARY HOSPITAL, SOUTHERN THAILAND.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Bacterial Toxins; beta-Lactamases; Ciprofloxacin; Drug Resistance, Microbial; Escherichia coli Infections; Escherichia coli Proteins; Female; Fimbriae, Bacterial; Hemolysin Proteins; Humans; Male; Middle Aged; Norfloxacin; Phylogeny; Tertiary Care Centers; Thailand; Urinary Tract Infections; Uropathogenic Escherichia coli; Virulence; Virulence Factors; Young Adult | 2015 |
The degradation of two fluoroquinolone based antimicrobials by SilA, an alkaline laccase from Streptomyces ipomoeae.
Topics: Anti-Infective Agents; Biotransformation; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Laccase; Norfloxacin; Streptomyces | 2016 |
Assessment of altered binding specificity of bacteriophage for ciprofloxacin-induced antibiotic-resistant Salmonella Typhimurium.
Topics: Ampicillin; Anti-Bacterial Agents; Bacterial Proteins; Bacteriophages; beta-Lactamases; Binding Sites; Chloramphenicol; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Membrane Transport Proteins; Microbial Sensitivity Tests; Norfloxacin; Salmonella typhimurium; Tetracycline; Trans-Activators | 2016 |
Electrochemical oxidation of fluoroquinolone antibiotics: Mechanism, residual antibacterial activity and toxicity change.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin | 2016 |
Fluorescent labelling of ciprofloxacin and norfloxacin and its application for residues analysis in surface water.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Environmental Monitoring; Fluorescent Dyes; Fresh Water; Norfloxacin; Oxadiazoles; Reproducibility of Results; Thailand | 2016 |
Direct Photolysis of Fluoroquinolone Antibiotics at 253.7 nm: Specific Reaction Kinetics and Formation of Equally Potent Fluoroquinolone Antibiotics.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Kinetics; Norfloxacin; Photolysis | 2016 |
Impact of AAC(6')-Ib-cr in combination with chromosomal-mediated mechanisms on clinical quinolone resistance in Escherichia coli.
Topics: Animals; Anti-Bacterial Agents; Chromosomes, Bacterial; Ciprofloxacin; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Genes, Bacterial; Male; Mice, Inbred C57BL; Microbial Sensitivity Tests; Microbial Viability; Norfloxacin; Peritonitis; Plasmids; Quinolones; Sepsis; Virulence | 2016 |
[Development of Determination Method of Fluoroquinolone Antibiotics in Sludge Based on Solid Phase Extraction and HPLC-Fluorescence Detection Analysis].
Topics: Adsorption; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluorescence; Fluoroquinolones; Norfloxacin; Ofloxacin; Sewage; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical | 2016 |
Low-dose norfloxacin and ciprofloxacin therapy worsen leptospirosis in hamster.
Topics: Animals; Anti-Bacterial Agents; Bacterial Load; Biopsy; Ciprofloxacin; Cricetinae; Cytokines; Disease Models, Animal; Female; Inflammation Mediators; Kidney; Leptospira; Leptospirosis; Lung; Norfloxacin; Treatment Failure | 2017 |
Detection of antibiotics in chicken eggs obtained from supermarkets in Ho Chi Minh City, Vietnam.
Topics: Animals; Anti-Bacterial Agents; Chickens; Chromatography, Liquid; Ciprofloxacin; Cities; Eggs; Enrofloxacin; Fluoroquinolones; Food Contamination; Norfloxacin; Tandem Mass Spectrometry; Vietnam | 2017 |
Quinolone Resistance Determinants of Clinical Salmonella Enteritidis in Thailand.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Clone Cells; DNA Gyrase; Drug Resistance, Bacterial; Gene Expression; Humans; Microbial Sensitivity Tests; Multilocus Sequence Typing; Mutation; Nalidixic Acid; Norfloxacin; Phylogeny; Plasmids; Prevalence; Salmonella enteritidis; Salmonella Infections; Thailand | 2017 |
In vitro evaluation of the antibacterial potential and modification of antibiotic activity of the Eugenia uniflora L. essential oil in association with led lights.
Topics: Anti-Bacterial Agents; Brazil; Chromatography, Gas; Ciprofloxacin; Drug Synergism; Escherichia coli; Eugenia; Light; Microbial Sensitivity Tests; Norfloxacin; Oils, Volatile; Staphylococcus aureus | 2017 |
Evaluation of lytic bacteriophages for control of multidrug-resistant Salmonella Typhimurium.
Topics: Anti-Bacterial Agents; Bacteriophages; Biological Control Agents; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Host-Pathogen Interactions; Hot Temperature; Hydrogen-Ion Concentration; Levofloxacin; Microbial Sensitivity Tests; Microbial Viability; Norfloxacin; Salmonella typhimurium; Tetracycline | 2017 |
Quantitative and automated MALDI-TOF MS-based detection of the plasmid-mediated quinolone resistance determinant AAC(6')-Ib-cr in Enterobacteriaceae.
Topics: Acetylation; Acetyltransferases; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Enterobacteriaceae; Norfloxacin; Plasmids; Quinolones; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2017 |
Amine-functionalized magnetic bamboo-based activated carbon adsorptive removal of ciprofloxacin and norfloxacin: A batch and fixed-bed column study.
Topics: Adsorption; Amines; Carbon; Charcoal; Ciprofloxacin; Norfloxacin; Water Pollutants, Chemical; Water Purification | 2018 |
Simultaneous removal of ciprofloxacin, norfloxacin, sulfamethoxazole by co-producing oxidative enzymes system of Phanerochaete chrysosporium and Pycnoporus sanguineus.
Topics: Anti-Bacterial Agents; Biotransformation; Ciprofloxacin; Coculture Techniques; Norfloxacin; Oxidation-Reduction; Oxidative Stress; Phanerochaete; Pycnoporus; Sulfamethoxazole | 2018 |
Cu
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Survival; Chelating Agents; Ciprofloxacin; Colonic Neoplasms; Coordination Complexes; Copper; Electrochemical Techniques; Humans; Lung Neoplasms; Mice; Molecular Structure; Norfloxacin; Phosphines; Reactive Oxygen Species; Structure-Activity Relationship | 2018 |
Variable-valence metals catalyzed solid NaBiO
Topics: Bismuth; Catalysis; Ciprofloxacin; Metals; Nanostructures; Norfloxacin; Ofloxacin; Oxidation-Reduction; Oxidative Stress; Oxygen; Sodium; X-Ray Diffraction | 2018 |
Optimization of process conditions for preparation of activated carbon from waste Salix psammophila and its adsorption behavior on fluoroquinolone antibiotics.
Topics: Adsorption; Anti-Bacterial Agents; Charcoal; Ciprofloxacin; Fluoroquinolones; Kinetics; Microscopy, Electron, Scanning; Norfloxacin; Phosphoric Acids; Salix; Solid Waste; Spectrometry, X-Ray Emission; Spectroscopy, Fourier Transform Infrared; Temperature; Waste Management; Water Pollutants, Chemical | 2018 |
[Effect of Fluoroquinolones on Performance and Microbial Community of a Vertical Flow Constructed Wetland].
Topics: Ammonia; Ciprofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Proteobacteria; Water Pollutants, Chemical; Wetlands | 2018 |
Replicon typing of plasmids in environmental Achromobacter sp. producing quinolone-resistant determinants.
Topics: Achromobacter; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Typing Techniques; Brazil; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Gene Expression; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Norfloxacin; Plasmids; Replicon; Soil Microbiology; Water Microbiology | 2018 |
An Integrated Microfluidic Platform for Quantifying Drug Permeation across Biomimetic Vesicle Membranes.
Topics: Anti-Bacterial Agents; Biomimetics; Ciprofloxacin; Drug Delivery Systems; Lab-On-A-Chip Devices; Liposomes; Microfluidics; Norfloxacin | 2019 |
Antimicrobial activity of Mimosa caesalpiniifolia Benth and its interaction with antibiotics against Staphylococcus aureus strains overexpressing efflux pump genes.
Topics: Anti-Bacterial Agents; Antiporters; Bacterial Proteins; Candida albicans; Ciprofloxacin; Drug Resistance, Multiple; Ethidium; Fluoroquinolones; Humans; Methylene Chloride; Microbial Sensitivity Tests; Mimosa; Multidrug Resistance-Associated Proteins; Norfloxacin; Plant Bark; Staphylococcal Infections; Staphylococcus aureus; Staphylococcus epidermidis; Tetracycline; Tetracycline Resistance | 2019 |
Association Between Peripheral Neuropathy and Exposure to Oral Fluoroquinolone or Amoxicillin-Clavulanate Therapy.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Case-Control Studies; Ciprofloxacin; Female; Fluoroquinolones; Humans; Incidence; Levofloxacin; Male; Middle Aged; Moxifloxacin; Norfloxacin; Ofloxacin; Peripheral Nervous System Diseases; Risk Factors; Sex Factors; United Kingdom | 2019 |
Highly Water-Stable Dye@Ln-MOFs for Sensitive and Selective Detection toward Antibiotics in Water.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Norfloxacin; Quinolones; Reproducibility of Results; Water; X-Ray Diffraction | 2019 |
Bacterial profile and antimicrobial susceptibility patterns in chronic suppurative otitis media at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Chronic Disease; Ciprofloxacin; Clarithromycin; Ethiopia; Hospitals, Special; Hospitals, University; Humans; Microbial Sensitivity Tests; Norfloxacin; Otitis Media, Suppurative; Proteus mirabilis; Staphylococcus aureus | 2019 |
Critical evaluation of third-order advantage with highly overlapped spectral signals. Determination of fluoroquinolones in fish-farming waters by fluorescence spectroscopy coupled to multivariate calibration.
Topics: Algorithms; Anti-Bacterial Agents; Calibration; Chile; Ciprofloxacin; Fisheries; Fluoroquinolones; Limit of Detection; Norfloxacin; Ponds; Spectrometry, Fluorescence; Water Pollutants, Chemical | 2019 |
Occurrence and distribution of selected antibiotics in the surface waters and ecological risk assessment based on the theory of natural disaster.
Topics: Anti-Bacterial Agents; China; Ciprofloxacin; Cities; Ecology; Ecosystem; Humans; Lakes; Natural Disasters; Norfloxacin; Risk Assessment; Seasons; Spatial Analysis; Water Pollutants, Chemical | 2019 |
Removal of aqueous fluoroquinolones with multi-functional activated carbon (MFAC) derived from recycled long-root Eichhornia crassipes: batch and column studies.
Topics: Adsorption; Anti-Infective Agents; Charcoal; Ciprofloxacin; Ecosystem; Eichhornia; Fluoroquinolones; Humans; Kinetics; Norfloxacin; Recycling; Thermodynamics; Water; Water Pollutants, Chemical; Water Purification | 2019 |
Degradation mechanism study of fluoroquinolones in UV/Fe
Topics: Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Iron; Mass Spectrometry; Norfloxacin; Oxidation-Reduction; Peroxides; Photolysis; Sulfates; Sulfuric Acids; Ultraviolet Rays; Water Pollutants, Chemical | 2020 |
Molecular Modification of Fluoroquinolone-Biodegrading Enzymes Based on Molecular Docking and Homology Modelling.
Topics: Amino Acids; Anti-Bacterial Agents; Binding Sites; Biodegradation, Environmental; Ciprofloxacin; Models, Molecular; Norfloxacin; Ofloxacin | 2019 |
Development of quinolone resistance and prevalence of different virulence genes among Shigella flexneri and Shigella dysenteriae in environmental water samples.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Humans; India; Membrane Transport Proteins; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Plasmids; Prevalence; Quinolones; Shigella dysenteriae; Shigella flexneri; Virulence | 2020 |
Fixed drug eruption due to norfloxacin with cross-reactivity to ciprofloxacin: A case report.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Cross Reactions; Drug Eruptions; Female; Humans; Middle Aged; Norfloxacin | 2020 |
Occurrence, sources and risk assessment of fluoroquinolones in dumpsite soil and sewage sludge from Chennai, India.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Cities; Environmental Monitoring; India; Norfloxacin; Ofloxacin; Risk Assessment; Sewage; Soil Pollutants; Waste Disposal Facilities; Water Pollutants, Chemical | 2020 |
Green synthesis of stable Fe,Cu oxide nanocomposites from loquat leaf extracts for removal of Norfloxacin and Ciprofloxacin.
Topics: Adsorption; Ciprofloxacin; Eriobotrya; Kinetics; Nanocomposites; Norfloxacin; Oxides; Plant Extracts; Spectroscopy, Fourier Transform Infrared; Water Pollutants, Chemical | 2020 |
Novel rapid room temperature synthesis of conjugated microporous polymer for metal-free photocatalytic degradation of fluoroquinolones.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Norfloxacin; Polymers; Temperature | 2020 |
Inhibition and eradication activity of truncated α-defensin analogs against multidrug resistant uropathogenic Escherichia coli biofilm.
Topics: alpha-Defensins; Amoxicillin; Anti-Bacterial Agents; Biofilms; Cefixime; Ciprofloxacin; Drug Resistance, Bacterial; Drug Synergism; Norfloxacin; Uropathogenic Escherichia coli | 2020 |
Occurrence, virulence genes, and antimicrobial profiles of Escherichia coli O157 isolated from ruminants slaughtered in Al Ain, United Arab Emirates.
Topics: Animals; Anti-Bacterial Agents; Camelus; Cattle; Cefotaxime; Chloramphenicol; Ciprofloxacin; Escherichia coli Infections; Escherichia coli Proteins; Feces; Female; Food Microbiology; Goats; Male; Microbial Sensitivity Tests; Norfloxacin; Polymyxin B; Prevalence; Ruminants; Sheep; Shiga-Toxigenic Escherichia coli; United Arab Emirates; Virulence Factors | 2020 |
Multi-phase distribution, spatiotemporal variation and risk assessment of antibiotics in a typical urban-rural watershed.
Topics: Anti-Bacterial Agents; China; Ciprofloxacin; Cities; Environmental Monitoring; Geologic Sediments; Lakes; Norfloxacin; Particulate Matter; Quinolones; Risk Assessment; Rivers; Seasons; Tetracycline; Water Pollutants, Chemical | 2020 |
The effect of Ultraviolet-B irradiation on the photodegradation of ciprofloxacin and norfloxacin as inhibitors of bacterial DNA replication and cell division in urea medium.
Topics: Cell Division; Ciprofloxacin; Culture Media; DNA Replication; DNA, Bacterial; Norfloxacin; Regression Analysis; Ultraviolet Rays; Urea | 2020 |
Basophil activation test in the diagnosis of hypersensitivity reactions to quinolones in a real-life setting.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Basophil Degranulation Test; Ciprofloxacin; Drug Hypersensitivity; Female; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Norfloxacin; Quinolones; Skin Tests; Young Adult | 2021 |
Potential biotransformation pathways and efficiencies of ciprofloxacin and norfloxacin by an activated sludge consortium.
Topics: Anti-Bacterial Agents; Biotransformation; Ciprofloxacin; Norfloxacin; RNA, Ribosomal, 16S; Sewage | 2021 |
A VigiBase descriptive study of fluoroquinolone induced disabling and potentially permanent musculoskeletal and connective tissue disorders.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Adverse Drug Reaction Reporting Systems; Arthralgia; Ciprofloxacin; Connective Tissue Diseases; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Musculoskeletal Diseases; Myalgia; Norfloxacin; Ofloxacin; Pain; Risk Factors; Tendinopathy; Tendons; Young Adult | 2021 |
New chemiluminescent method of levofloxacin and ofloxacin determination based on terbium (III)-sensitized fluoroquinolone-KBrO
Topics: Ciprofloxacin; Fluoroquinolones; Levofloxacin; Norfloxacin; Terbium | 2021 |
Design, synthesis, molecular modeling, and antimicrobial potential of novel 3-[(1H-pyrazol-3-yl)imino]indolin-2-one derivatives as DNA gyrase inhibitors.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; Indoles; Microbial Sensitivity Tests; Models, Molecular; Molecular Docking Simulation; Norfloxacin; Pyrazoles; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2022 |
Repurposing Approved Drugs as Fluoroquinolone Potentiators to Overcome Efflux Pump Resistance in Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Carrier Proteins; Ciprofloxacin; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Repositioning; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Multidrug Resistance-Associated Proteins; Norfloxacin; Pyrvinium Compounds; Raloxifene Hydrochloride; Staphylococcal Infections; Staphylococcus aureus | 2021 |
In silico toxicity evaluation for transformation products of antimicrobials, from aqueous photolysis degradation.
Topics: Anti-Infective Agents; Ciprofloxacin; Mutagens; Norfloxacin; Photolysis; Sulfamethoxazole; Water; Water Pollutants, Chemical | 2022 |
A novel terbium (III) and aptamer-based probe for label-free detection of three fluoroquinolones in honey and water samples.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Honey; Norfloxacin; Terbium; Water | 2022 |
The effect of fluoroquinolones and antioxidans on biofilm formation by Proteus mirabilis strains.
Topics: Anti-Bacterial Agents; Ascorbic Acid; Biofilms; Ciprofloxacin; Fluoroquinolones; Humans; Norfloxacin; Proteus mirabilis; Rutin | 2022 |
Efficient with low-cost removal and adsorption mechanisms of norfloxacin, ciprofloxacin and ofloxacin on modified thermal kaolin: experimental and theoretical studies.
Topics: Adsorption; Ciprofloxacin; Humans; Kaolin; Kinetics; Models, Theoretical; Norfloxacin; Ofloxacin; Water Pollutants, Chemical | 2022 |
Association of Higher-Dose Fluoroquinolone Therapy With Serious Adverse Events in Older Adults With Advanced Chronic Kidney Disease.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Ciprofloxacin; Cohort Studies; Death, Sudden, Cardiac; Female; Fluoroquinolones; Humans; Hypoglycemia; Levofloxacin; Norfloxacin; Ontario; Renal Dialysis; Renal Insufficiency, Chronic; Retinal Detachment; Sepsis | 2022 |
Antibiotics and antimycotics in waste water treatment plants: Concentrations, removal efficiency, spatial and temporal variations, prediction, and ecological risk assessment.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Clotrimazole; Environmental Monitoring; Moxifloxacin; Norfloxacin; Ofloxacin; Pefloxacin; Risk Assessment; Sewage; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Water Purification | 2022 |
Association between prenatal antibiotics exposure and measures of fetal growth: A repeated-measure study.
Topics: Anti-Bacterial Agents; Birth Weight; Ciprofloxacin; Female; Fetal Development; Humans; Infant, Newborn; Maternal Exposure; Norfloxacin; Pregnancy; Premature Birth; Sulfamethoxazole; Tandem Mass Spectrometry | 2022 |
ADMET study, spectroscopic characterization and effect of synthetic nitro chalcone in combination with norfloxacin, ciprofloxacin, and ethidium bromide against Staphylococcus aureus efflux pumps.
Topics: Anti-Bacterial Agents; Chalcone; Chalcones; Ciprofloxacin; Ethidium; Humans; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Norfloxacin; Staphylococcal Infections; Staphylococcus aureus | 2023 |
Molecular characteristics of fluoroquinolone-resistant Escherichia coli isolated from suckling piglets with colibacillosis.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; beta-Lactamases; Ciprofloxacin; DNA Gyrase; Enrofloxacin; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Norfloxacin; Quinolones; Sulfonamides; Swine | 2022 |
Occurrences, transport drivers, and risk assessments of antibiotics in typical oasis surface and groundwater.
Topics: Anti-Bacterial Agents; China; Ciprofloxacin; Ecosystem; Environmental Monitoring; Groundwater; Norfloxacin; Oxygen; Pefloxacin; Risk Assessment; Water; Water Pollutants, Chemical | 2022 |
Association between initiation of fluoroquinolones and hospital admission or emergency department visit for suicidality: population based cohort study.
Topics: Adult; Anti-Bacterial Agents; Azithromycin; Ciprofloxacin; Cohort Studies; Emergency Service, Hospital; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Hospitals; Humans; Levofloxacin; Moxifloxacin; Norfloxacin; Retrospective Studies; Suicidal Ideation; Suicide; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections | 2022 |
Simultaneous adsorptive removal of three fluoroquinolones using humic acid modified hydrogel beads.
Topics: Adsorption; Chitosan; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Humic Substances; Hydrogels; Hydrogen-Ion Concentration; Kinetics; Norfloxacin; Water; Water Pollutants, Chemical | 2023 |
Comparative selective pressure potential of antibiotics in the environment.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Norfloxacin; Tetracycline | 2023 |
Fluorescent strip sensor for rapid and ultrasensitive determination of fluoroquinolones in fish and milk.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Humans; Milk; Norfloxacin; Ofloxacin; Pefloxacin | 2023 |
A comprehensive description of the TolC effect on the antimicrobial susceptibility profile in
Topics: Anti-Bacterial Agents; Ciprofloxacin; Enterobacter cloacae; Erythromycin; Escherichia coli; Humans; Microbial Sensitivity Tests; Norfloxacin; Tetracycline | 2022 |
Monitoring fluoroquinolone resistance among ESBL-positive and ESBL-negative Escherichia coli strains isolated from urinary tract infections: An alert for empirical treatment.
Topics: Anti-Bacterial Agents; beta-Lactamases; Ciprofloxacin; Community-Acquired Infections; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Norfloxacin; Urinary Tract Infections | 2023 |
Field measures of strengthen plant-microbial remediation of PAHs-FQs compound pollution.
Topics: Ciprofloxacin; Enrofloxacin; Fluorenes; Molecular Docking Simulation; Norfloxacin; Ofloxacin; Peroxidases; Polycyclic Aromatic Hydrocarbons | 2023 |
A luminous strategy for the recognition of toxic antibiotics in water via efficient energy transfer.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Energy Transfer; Fluoroquinolones; India; Metal-Organic Frameworks; Norfloxacin; Ofloxacin; Water | 2023 |
Magnetic Fe
Topics: Algorithms; Anti-Bacterial Agents; Ciprofloxacin; Levofloxacin; Magnetic Phenomena; Norfloxacin | 2023 |
An investigation on removal of ciprofloxacin and norfloxacin by phycoremediation with an emphasis on acute toxicity and biochemical composition.
Topics: Anti-Bacterial Agents; Chlorella vulgaris; Chlorophyceae; Ciprofloxacin; Norfloxacin | 2023 |
Photocatalytic degradation of fluoroquinolone antibiotics using chitosan biopolymer functionalized copper oxide nanoparticles prepared by facile sonochemical method.
Topics: Anti-Bacterial Agents; Chitosan; Ciprofloxacin; Copper; Fluoroquinolones; Nanoparticles; Norfloxacin; Oxides | 2023 |
An optimized electro-fenton pretreatment for the degradation and mineralization of a mixture of ofloxacin, norfloxacin, and ciprofloxacin.
Topics: Carboxylic Acids; Ciprofloxacin; Electrodes; Fluoroquinolones; Hydrogen Peroxide; Norfloxacin; Ofloxacin; Oxidation-Reduction; Water Pollutants, Chemical | 2023 |