ciprofloxacin has been researched along with lomefloxacin in 131 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (7.63) | 18.7374 |
| 1990's | 52 (39.69) | 18.2507 |
| 2000's | 46 (35.11) | 29.6817 |
| 2010's | 23 (17.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bridges, AJ; Culbertson, TP; Domagala, JM; Gambino, L; Hagen, SE; Karrick, G; Porter, K; Sanchez, JP; Sesnie, JA; Spense, FG | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Antón-Fos, GM; Duart, MJ; Mut-Ronda, S; Salabert-Salvador, MT | 1 |
| Baroni, M; Cecchetti, V; Cianchetta, G; Cruciani, G; Mannhold, R | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Arakawa, Y; Kato, H; Kimura, K; Konda, T; Shibata, N; Shibayama, K; Suzuki, S; Wachino, J; Yamane, K | 1 |
| China, A; Dinakaran, M; Nagaraja, V; Senthilkumar, P; Sriram, D; Yogeeswari, P | 1 |
| Long, F; Rouquette-Loughlin, C; Shafer, WM; Yu, EW | 1 |
| Brun, R; Ma, X; Zhou, W | 1 |
| Baliani, A; Barrett, MP; Chollet, C; Gilbert, IH; Wong, PE | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Azéma, J; Dewelle, J; Guidetti, B; Kiss, R; Korolyov, A; Le Calve, B; Malet-Martino, M; Martino, R; Mijatovic, T; Vaysse, J | 1 |
| Dempsey, S; Jack, C; Miller, CH; Nisa, S; O'Toole, R | 1 |
| Avdeef, A; Sun, N; Tam, KY; Tsinman, O | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Sen, S; Sinha, N | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Akylbekov, N; Bulatova, A; Burilov, A; Chugunova, E; Dobrynin, A; Gavrilov, N; Kulik, N; Syakaev, V; Voloshina, A; Zobov, V | 1 |
| Feng, LS; Liu, X; Pan, B; Zhang, GF; Zhang, S | 1 |
| Bai, L; Deng, JL; Gao, F; Lv, ZS; Wang, Y; Xu, Z; Zhang, F; Zhao, SJ | 1 |
| Guo, H | 1 |
| Ciura, K; Fallarero, A; Fedorowicz, J; Gilbert-Girard, S; Konopacka, A; Lejnowski, D; Morawska, M; Sączewski, J; Savijoki, K; Skok, Ž; Tomašič, T; Waleron, K | 1 |
| Blaskovich, MAT; Pham, TDM; Ziora, ZM | 1 |
| Debbia, EA; Pesce, A; Schito, GC | 1 |
| García, I; Pascual, A; Perea, EJ | 1 |
| Cox, CE | 1 |
| Jones, RN | 1 |
| Adler, LP; Bednarczyk, EM; Berridge, MS; Green, JA; Leisure, GP; Little, D; Miraldi, FD; Nelson, AD; Panacek, EA | 1 |
| Bornigia, S; De Sio, G; Morbiducci, V; Piersimoni, C; Scalise, G | 1 |
| Bartlett, RC; Mazens-Sullivan, MF; McCarter, YS | 1 |
| Hashmi, ZS; Smith, JM | 1 |
| Andrews, JM; Baldwin, DR; Honeybourne, D; Wise, R | 1 |
| Conejo, MC; García, I; Pascual, A; Perea, EJ | 1 |
| Barry, AL; Fuchs, PC | 1 |
| Pattyn, SR | 1 |
| McDonald, PJ; Pruul, H | 1 |
| Allen, RA; Amyes, SG; Lewin, CS | 1 |
| Borsa-Lebas, F; Dhib, M; Fillastre, JP; Humbert, G; Leroy, A; Moulin, B | 1 |
| Hall, MC; Piddock, LJ; Wise, R | 1 |
| Atkinson, HC; Begg, EJ; Frampton, CM; Robson, RA; Saunders, DA | 1 |
| Matsumoto, F; Morita, M; Takahashi, T | 1 |
| Bhattacharya, SS; Lal, HM; Lalitha, MK; Nisha, AK; Ramamoorthy, U | 1 |
| Clarke, AM; Zemcov, SJ | 1 |
| Greenwood, D; Kanematsu, M | 1 |
| Arakawa, S; Fujii, A; Kamidono, S; Maeda, H; Nakata, K | 1 |
| Andrews, JM; Ashby, JP; Matthews, RS; Wise, R | 1 |
| Fernandes, PB; Swanson, RN | 1 |
| Nagayama, A; Nakao, T; Taen, H | 1 |
| Chin, NX; Neu, HC; Novelli, A | 1 |
| Dohtsu, Y; Hara, K; Hayashi, T; Hirota, M; Koga, H; Kohno, S; Saito, A; Yamaguchi, K | 1 |
| Nishino, T; Obana, Y | 1 |
| Finch, R; Martin, J; Pilkington, R | 1 |
| Koeppe, P; Lode, H; Rost, KL; Schaberg, T; Stuht, H | 1 |
| Beskid, G; Prosser, BL | 2 |
| el-Kersh, TA; Ramadan, MA; Shibl, AM; Tawfik, AF | 1 |
| D'iakov, SI; Katsalukha, VV; Lebedeva, IK; Lukashina, AV; Raĭskaia, VA | 1 |
| Fujita, H; Matsuo, I | 1 |
| Dutov, VV; Kalinin, VN; Nasonov, VN; Nekhorosheva, AG; Rusanova, EV; Savitskaia, KI; Shanina, AG; Solodilova, OE; Trapeznikova, MF | 1 |
| Croizé, J; Le Noc, D; Le Noc, P | 1 |
| Belliveau, P; Crowe, H; Gousee, G; Nightingale, CH; Quintiliani, R | 1 |
| Andrews, JM; Baldwin, DR; Gill, M; Honeybourne, D; Wise, R | 1 |
| Hale, JA; Knapp, JS; Neal, SW; Rice, RJ; Whittington, WL; Wintersheid, K | 1 |
| Appelbaum, PC; Jacobs, MR; Visalli, MA | 1 |
| Iakovlev, SV; Iakovlev, VP; Izotova, GN | 1 |
| Cheung, MM; Ho, NK; Kam, KM; Wong, PW | 1 |
| Bartoletti, R; Pisani, E; Rizzo, M; Trinchieri, A | 1 |
| Albertini, S; Chételat, AA; Gocke, E | 1 |
| Kunichan, AD; Mozhokina, GN; Shapatava, MN | 1 |
| Klecak, G; Urbach, F; Urwyler, H | 1 |
| Forbes, PD; Mäkinen, M; Stenbäck, F | 1 |
| Anan'eva, LP; Belov, BS; Nasonova, VA; Shubin, SV; Soldatova, SI; Tarasova, GM; Urumova, MM; Ushakova, MA | 1 |
| Arakane, K; Hirobe, M; Mashiko, S; Nagano, T; Ryu, A; Umezawa, N | 1 |
| Chen, D; Prahalad, AK; Rosen, JE; Schlüter, G; Williams, GM | 1 |
| Choi, EC; Kang, JA; Kim, BK; Kim, JH; Kim, JW; Kim, YG; Lee, JH | 1 |
| Hoogkamp-Korstanje, JA | 1 |
| Choi, EC; Choi, KH; Kim, BK; Kim, JH; Kim, JW; Lee, JH | 1 |
| Kawada, A; Kimura, M | 1 |
| Baumann-Wilschke, I; Förster, C; Rücker, M; Shakibaei, M; Stahlmann, R; Vormann, J | 1 |
| Belousov, IuB; Efremenkova, OV; Komarova, VP | 1 |
| Anjo, S; Hara, A; Nakamura, M; Sakai, M | 1 |
| Gomi, H; Hatanaka, K; Kawada, A; Matsuo, I | 1 |
| Greenberg, RN; Newman, MT; Pectol, RW; Shariaty, S | 1 |
| Agarwal, HC; Biswas, NR; Gupta, SK; Gupta, YK; Velpandian, T | 1 |
| Al-Ajmi, H; Colman, PJ; Ferguson, J; McEwen, J; Purkins, L; Willavize, SA | 1 |
| Bubnov, VP; D'iakov, SI; Lebedeva, IK; Moskalenko, VI; Sidorenko, SV | 1 |
| Leitão, ML; Redinha, JS; Teixeira, F; Teixeira, MH | 1 |
| Castell, JV; Morlière, P; Ouédraogo, G; Santus, R | 1 |
| Gordon, YJ; Kowalski, RP; Romanowski, EG; Yates, KA | 1 |
| Gonçalves, NJ; Maya, MT; Morais, JA; Silva, NB | 1 |
| Bai, ZZ; Guan, DW; Zhang, QS | 1 |
| Feng, P; Lei, B; Lu, X; Xia, P; Zhong, L | 1 |
| Schaeffer, AJ | 1 |
| Naber, KG | 2 |
| Hayakawa, H; Kawamura, Y; Miyazaki, M; Nagasawa, M; Nakamura, S; Nojima, Y | 1 |
| Fukuda, H; Kawamura, Y | 1 |
| Li, JL; Ma, XC; Tu, ZH; Xin, J; Zhang, T | 2 |
| Chiang, SR; Chuang, YC; Ko, WC; Lee, HC; Tang, HJ; Wang, YY | 1 |
| Ono, C; Tanaka, M | 1 |
| Hong, JW; Hu, CQ; Sheng, LS | 1 |
| Booranapong, W; Kosrirukvongs, P; Prabhasawat, P; Srivannaboon, S; Suttiprakarn, P | 1 |
| Hatano, K | 1 |
| Holzgrabe, U; Kiefer, W; Neugebauer, U; Popp, J; Schmitt, M; Szeghalmi, A | 1 |
| Paramasivan, CN; Rahman, F; Sulochana, S | 1 |
| Abba, M; Donnelly, J; Hussain, B; Shervington, LA | 1 |
| Depta, JP; Pichler, WJ; Schmid, DA | 1 |
| Romero, IC; Saravia, NG; Walker, J | 1 |
| Bayar, B; Bozkurt, A; Dinçel, A; Duman, S; Kaya, E; Oflu, Y; Yağci, R; Yağci, S | 1 |
| Gross-Tholl, N; Herbold, B; von Keutz, E; Wirnitzer, U | 1 |
| Andreeva, I; Rafalsky, V; Rjabkova, E | 1 |
| Huang, CH; Zhang, H | 1 |
| Li, H; Lin, J; Lin, JM; Wei, S | 1 |
| Chen, X; Hua, H; Ji, C; Lin, X; Liu, Y; Tang, S; Yue, Z | 1 |
| Marazuela, MD; Moreno-Bondi, MC; Rodriguez, E | 1 |
| Kim, J; Ohtani, H; Sawada, Y; Tsujimoto, M | 1 |
| Carda-Broch, S; Esteve-Romero, J; Rambla-Alegre, M | 1 |
| Gao, P; Li, YW; Mo, CH; Ruan, ZL; Tai, YP; Wang, QJ; Xu, JW; Zhang, Y | 1 |
| Alves, G; Falcão, A; Fortuna, A; Lino, C; Pena, A; Sousa, J | 1 |
| Li, YW; Mo, CH; Su, QY; Tai, YP; Wang, JY; Wu, XL; Zhang, Y | 1 |
| Jiang, W; Korshin, GV; Liu, C; Nanaboina, V | 1 |
| Haritova, AM; Krustev, SZ; Rusenova, NV | 1 |
| Bosca, F; Consuelo Cuquerella, M; Edge, R; Lhiaubet-Vallet, V; Soldevila, S | 1 |
| Cai, QH; Chen, GH; Chen, P; Guo, X; Meng, HL; Tian, YF | 1 |
| Albini, A; Cazzalini, O; Fasani, E; Ferraro, D; Maccario, C; Mocchi, R; Perucca, P; Pizzala, R; Pretali, L; Savio, M; Sommatis, S; Stivala, LA | 1 |
| Cui, YF; He, JT; Qiao, XC; Su, SH; Yang, L | 1 |
| Chen, B; Han, J; Lu, Y; Tan, Z; Wang, Y; Yan, Y; Yu, M | 1 |
| Dai, LL; Dai, XH; Li, N; Liu, HJ; Xue, YG; Yan, H | 1 |
| Beberok, A; Buszman, E; Delijewski, M; Otręba, M; Respondek, M; Rok, J; Rzepka, Z; Wrześniok, D | 1 |
12 review(s) available for ciprofloxacin and lomefloxacin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
4-Quinolone derivatives and their activities against Gram positive pathogens.
Topics: 4-Quinolones; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 2018 |
Fluoroquinolone-isatin hybrids and their biological activities.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Antitubercular Agents; Antiviral Agents; Fluoroquinolones; Humans; Isatin; Structure-Activity Relationship | 2019 |
Isatin derivatives and their anti-bacterial activities.
Topics: Anti-Bacterial Agents; Bacteria; Humans; Isatin; Structure-Activity Relationship | 2019 |
Quinolone antibiotics.
Topics: | 2019 |
Pharmacokinetics of quinolones in renal insufficiency.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Glomerular Filtration Rate; Half-Life; Humans; Kidney Failure, Chronic; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1990 |
Oral ciprofloxacin, ofloxacin, and lomefloxacin as alternatives to intravenous antimicrobial therapy.
Topics: Administration, Oral; Anti-Bacterial Agents; Ciprofloxacin; Drug Costs; Drug Tolerance; Female; Fluoroquinolones; Gram-Negative Aerobic Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Cocci; Humans; Male; Ofloxacin; Quinolones; Treatment Outcome | 1993 |
[Pharmacokinetics of fluoroquinolones in patients with renal insufficiency].
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Ofloxacin; Pefloxacin; Quinolones; Renal Insufficiency | 1995 |
The expanding role of fluoroquinolones.
Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Urinary Tract Infections | 2002 |
Levofloxacin in the treatment of urinary tract infections and prostatitis.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Cross Infection; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Microbial; Female; Fluoroquinolones; Follow-Up Studies; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Prostatitis; Quinolones; Severity of Illness Index; Treatment Outcome; Urinary Tract Infections | 2004 |
Quinolones for uncomplicated acute cystitis in women.
Topics: Acute Disease; Adult; Anti-Infective Agents, Urinary; Ciprofloxacin; Cystitis; Female; Fluoroquinolones; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Randomized Controlled Trials as Topic | 2006 |
Determination of four fluoroquinolone antibiotics in tap water in Guangzhou and Macao.
Topics: Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Water Pollutants, Chemical; Water Supply | 2010 |
12 trial(s) available for ciprofloxacin and lomefloxacin
| Article | Year |
|---|---|
A comparison of the safety and efficacy of lomefloxacin and ciprofloxacin in the treatment of complicated or recurrent urinary tract infections.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Escherichia coli Infections; Female; Fluoroquinolones; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Quinolones; Recurrence; Single-Blind Method; Treatment Outcome; Urinary Tract Infections | 1992 |
Comparative assessment of the effect of lomefloxacin, ciprofloxacin, and placebo on cerebral blood flow, and glucose and oxygen metabolism in healthy subjects by positron emission tomography.
Topics: Adolescent; Adult; Anti-Infective Agents; Brain; Cerebrovascular Circulation; Ciprofloxacin; Female; Fluoroquinolones; Glucose; Humans; Male; Oxygen; Quinolones; Tomography, Emission-Computed | 1992 |
Comparative effects of ciprofloxacin and lomefloxacin on the oxidative metabolism of theophylline.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Fluoroquinolones; Humans; Male; Oxidation-Reduction; Quinolones; Random Allocation; Theophylline | 1990 |
Interaction study of lomefloxacin and ciprofloxacin with omeprazole and comparative pharmacokinetics.
Topics: Adult; Anti-Infective Agents; Biotransformation; Chromatography, High Pressure Liquid; Ciprofloxacin; Double-Blind Method; Drug Interactions; Female; Fluoroquinolones; Half-Life; Humans; Male; Omeprazole; Quinolones | 1995 |
[Maxaquin and ciprofloxacin in the treatment of complicated and recurrent urinary infections in adults].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Female; Fluoroquinolones; Humans; Male; Middle Aged; Quinolones; Recurrence; Urinary Tract Infections | 1994 |
Comparative bronchoalveolar concentrations of ciprofloxacin and lomefloxacin following oral administration.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchi; Bronchoalveolar Lavage Fluid; Ciprofloxacin; Female; Fluoroquinolones; Humans; Male; Middle Aged; Mucous Membrane; Quinolones | 1993 |
Lomefloxacin versus ciprofloxacin in the treatment of complicated urinary tract infections: a multicenter study.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Escherichia coli; Female; Fluoroquinolones; Humans; Italy; Klebsiella; Male; Middle Aged; Proteus; Pseudomonas; Quinolones; Streptococcus; Treatment Outcome; Urinary Tract Infections | 1996 |
[Selection of antibacterial therapy for treatment of infections in elderly patients].
Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Cefaclor; Cephalosporins; Ciprofloxacin; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Male; Quinolones; Respiratory Tract Infections | 1998 |
Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis.
Topics: Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Fluoroquinolones; Follow-Up Studies; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Osteomyelitis; Quinolones | 2000 |
A comparison of the photosensitizing potential of trovafloxacin with that of other quinolones in healthy subjects.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Male; Naphthyridines; Photosensitivity Disorders; Quinolones; Single-Blind Method; Skin; Ultraviolet Rays | 2000 |
Lomefloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Fluoroquinolones; Humans; Male; Prostatitis; Pseudomonas; Quinolones; Treatment Outcome; Urinary Tract Infections | 2002 |
Comparison of topical lomefloxacin 0.3 per cent versus topical ciprofloxacin 0.3 per cent for the treatment of presumed bacterial corneal ulcers.
Topics: Administration, Topical; Adolescent; Adult; Anti-Infective Agents; Chi-Square Distribution; Child; Child, Preschool; Ciprofloxacin; Corneal Ulcer; Double-Blind Method; Female; Fluoroquinolones; Humans; Male; Middle Aged; Prospective Studies; Quinolones; Statistics, Nonparametric; Treatment Outcome | 2004 |
107 other study(ies) available for ciprofloxacin and lomefloxacin
| Article | Year |
|---|---|
Synthesis and biological activity of 5-amino- and 5-hydroxyquinolones, and the overwhelming influence of the remote N1-substituent in determining the structure-activity relationship.
Topics: Alkylation; Aminoquinolines; Animals; Anti-Bacterial Agents; Bacterial Infections; Chemical Phenomena; Chemistry; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydroxyquinolines; Mice; Microbial Sensitivity Tests; Molecular Structure; Piperazines; Pyrrolidines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1991 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Search compounds with antimicrobial activity by applying molecular topology to selected quinolones.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Discriminant Analysis; Drug Design; Microbial Sensitivity Tests; Quantitative Structure-Activity Relationship; Quinolones | 2003 |
Chemometric studies on the bactericidal activity of quinolones via an extended VolSurf approach.
Topics: Anti-Bacterial Agents; Enterococcus faecalis; Escherichia coli; Models, Molecular; Pseudomonas aeruginosa; Quantitative Structure-Activity Relationship; Quinolones; Staphylococcus aureus; Thermodynamics | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chitosan; Conjugation, Genetic; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Humans; Malates; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Transformation, Bacterial; Uncoupling Agents | 2007 |
Antimycobacterial activities of novel 1-(cyclopropyl/tert-butyl/4-fluorophenyl)-1,4-dihydro- 6-nitro-4-oxo-7-(substituted secondary amino)-1,8-naphthyridine-3-carboxylic acid.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Drug Resistance, Multiple, Bacterial; Female; Light; Mice; Microbial Sensitivity Tests; Mycobacterium smegmatis; Mycobacterium tuberculosis; Naphthyridines; Structure-Activity Relationship; Topoisomerase II Inhibitors; Vero Cells | 2007 |
Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli.
Topics: Anti-Bacterial Agents; Antiporters; ATP-Binding Cassette Transporters; Bacterial Proteins; Cloning, Molecular; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Ethidium; Fluorescence Polarization; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin | 2008 |
Synthesis, in vitro antitrypanosomal and antibacterial activity of phenoxy, phenylthio or benzyloxy substituted quinolones.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Chagas Disease; Chemistry, Pharmaceutical; Drug Design; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Models, Chemical; Nitroimidazoles; Quinolones; Trypanocidal Agents; Trypanosoma cruzi | 2009 |
Targeted delivery of compounds to Trypanosoma brucei using the melamine motif.
Topics: Animals; Eflornithine; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Triazines; Trypanocidal Agents; Trypanosoma brucei brucei | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Ciprofloxacin; Humans; Maximum Tolerated Dose; Mice; Neoplasms; Piperazine; Piperazines | 2009 |
Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
Topics: Antitubercular Agents; Cysteine; Drug Evaluation, Preclinical; Mycobacterium; Mycobacterium smegmatis; Organoselenium Compounds; Selenocysteine; Small Molecule Libraries | 2009 |
The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability.
Topics: Caco-2 Cells; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Membranes, Artificial; Molecular Structure; Pharmaceutical Preparations | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Synthesis and biological evaluation of novel structural hybrids of benzofuroxan derivatives and fluoroquinolones.
Topics: Anti-Bacterial Agents; Bacteria; Benzoxazoles; Chemistry Techniques, Synthetic; Drug Design; Fluoroquinolones; Hemolysis; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Structure-Activity Relationship | 2016 |
Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents.
Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Positive Bacteria; HEK293 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Quaternary Ammonium Compounds; Quinolones; Structure-Activity Relationship | 2019 |
In vitro assessment of the postantibiotic effect of lomefloxacin against gram-positive and gram-negative pathogens.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Time Factors | 1992 |
Comparative penetration of lomefloxacin and other quinolones into human phagocytes.
Topics: Analysis of Variance; Anti-Infective Agents; Ascitic Fluid; Ciprofloxacin; Fluoroquinolones; Humans; In Vitro Techniques; Macrophages; Neutrophils; Norfloxacin; Ofloxacin; Quinolones | 1992 |
In vitro evaluation of E-4695, a new fluoro-naphthyridine.
Topics: Anti-Bacterial Agents; Azetidines; Bacteria; Ciprofloxacin; Drug Evaluation, Preclinical; Enoxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones | 1992 |
In vitro activity of the new quinolone lomefloxacin against Mycobacterium tuberculosis.
Topics: Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones | 1992 |
The comparative activity of fleroxacin, three other quinolones and eight unrelated antimicrobial agents.
Topics: Anti-Bacterial Agents; Cephalosporins; Ciprofloxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1992 |
Outer membrane changes in quinolone resistant Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Pseudomonas aeruginosa; Quinolones | 1991 |
Comparative pharmacokinetic disposition of fluoroquinolones in the lung.
Topics: Administration, Oral; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Injections, Intravenous; Lung; Quinolones | 1991 |
Fluorometric and high-performance liquid chromatographic measurement of quinolone uptake by human neutrophils.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fleroxacin; Fluorescence; Fluoroquinolones; Humans; Neutrophils; Norfloxacin; Ofloxacin; Quinolones | 1991 |
Cross-resistance and cross-susceptibility between fluoroquinolone agents.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Predictive Value of Tests; Quinolones | 1991 |
Anti-Mycobacterium leprae activity of several quinolones studied in the mouse.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Leprosy; Mice; Mycobacterium leprae; Quinolones | 1991 |
Lomefloxacin-induced modification of the kinetics of growth of gram-negative bacteria and susceptibility to phagocytic killing by human neutrophils.
Topics: Anti-Infective Agents; Cell Division; Ciprofloxacin; Escherichia coli; Fluoroquinolones; Gram-Negative Bacteria; Humans; Neutrophils; Norfloxacin; Nucleic Acids; Phagocytosis; Pseudomonas aeruginosa; Quinolones; Tritium | 1990 |
Antibacterial activity of fluoroquinolones in combination with zidovudine.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enoxacin; Enterobacteriaceae; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Salmonella; Staphylococcus; Zidovudine | 1990 |
Mechanism of action of lomefloxacin.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; DNA Topoisomerases, Type II; DNA, Bacterial; DNA, Superhelical; Fluoroquinolones; Kinetics; Microbial Sensitivity Tests; Norfloxacin; Quinolones; Rec A Recombinases | 1990 |
[Therapeutic drug monitoring of fluoroquinolone].
Topics: Anti-Infective Agents; Bile; Biological Assay; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones; Sputum | 1990 |
Susceptibility pattern of bacterial isolates to lomefloxacin.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Nalidixic Acid; Norfloxacin; Quinolones | 1990 |
Comparative in vitro activity of lomefloxacin, a new difluoroquinolone.
Topics: Anti-Infective Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Ceftazidime; Ciprofloxacin; Drug Evaluation, Preclinical; Fluoroquinolones; Gentamicins; Microbial Sensitivity Tests; Norfloxacin; Quinolones | 1989 |
Studies on the emergence of resistance to lomefloxacin in vitro.
Topics: Anti-Infective Agents; Ciprofloxacin; Cystitis; Drug Resistance, Microbial; Escherichia coli; Fluoroquinolones; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Biological; Norfloxacin; Quinolones | 1989 |
In vitro activities of T-3262, NY-198, fleroxacin (AM-833; RO 23-6240), and other new quinolone agents against clinically isolated Chlamydia trachomatis strains.
Topics: Anti-Infective Agents; Chlamydia; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Naphthyridines; Quinolones | 1988 |
In vitro activity of lomefloxacin, a new quinolone antimicrobial agent, in comparison with those of other agents.
Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria; Blood Proteins; Cefuroxime; Ciprofloxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Ofloxacin; Oxazines; Protein Binding; Pseudomonas aeruginosa; Quinolines; Quinolones; Staphylococcus; Streptococcus; Trimethoprim | 1988 |
Correlation of in vitro activities of the fluoroquinolones to their in vivo efficacies.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1988 |
In vitro activities of ofloxacin and four other new quinoline-carboxylic acids against Chlamydia trachomatis.
Topics: Anti-Infective Agents; Chlamydia trachomatis; Ciprofloxacin; Doxycycline; Fleroxacin; Fluoroquinolones; Minocycline; Norfloxacin; Ofloxacin; Quinolones | 1988 |
In vitro activity of lomefloxacin (SC-47111; NY-198), a difluoroquinolone 3-carboxylic acid, compared with those of other quinolones.
Topics: Anaerobiosis; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Magnesium; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Quinolones | 1988 |
Efficacy of NY-198 against experimental Legionnaires disease.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Guinea Pigs; Legionnaires' Disease; Male; Quinolones; Tissue Distribution | 1988 |
Therapeutic efficacy of ofloxacin, ciprofloxacin and NY-198 in experimentally infected normal and alloxan-induced diabetic mice.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Diabetes Mellitus, Experimental; Female; Fluoroquinolones; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Ofloxacin; Pyelonephritis; Quinolones; Respiratory Tract Infections; Urinary Tract Infections | 1988 |
In-vitro assessment of lomefloxacin (SC-47111)--a new quinolone derivative.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones | 1988 |
Multicenter in vitro comparative study of fluoroquinolones against 25,129 gram-positive and gram-negative clinical isolates.
Topics: Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1995 |
In vitro activity of subinhibitory concentrations of quinolones on urea-splitting bacteria: effect on urease activity and on cell surface hydrophobicity.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enterobacteriaceae; Fluoroquinolones; Norfloxacin; Ofloxacin; Proteus; Providencia; Quinolones; Surface Properties; Urea; Urease | 1995 |
[Comparative evaluation of the effectiveness of fluoroquinolones in experimental anthrax infection].
Topics: Animals; Anthrax; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; Drug Evaluation, Preclinical; Evaluation Studies as Topic; Fluoroquinolones; Lethal Dose 50; Mice; Microbial Sensitivity Tests; Pefloxacin; Quinolones | 1994 |
In vitro phototoxic activities of new quinolone antibacterial agents: lipid peroxidative potentials.
Topics: Absorption; Anti-Infective Agents; Azides; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Lipid Peroxidation; Norfloxacin; Ofloxacin; Oxygen; Photochemistry; Photosensitivity Disorders; Quinolones; Sodium Azide; Squalene; Ultraviolet Rays | 1994 |
[Compared antibacterial activity of a new fluoroquinolone, sparfloxacin (AT 4140, RP 64206) and four other fluoroquinolones against 332 strains of enteropathogen bacteria].
Topics: Anti-Infective Agents; Campylobacter jejuni; Ciprofloxacin; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Helicobacter pylori; Humans; In Vitro Techniques; Ofloxacin; Pefloxacin; Quinolones; Salmonella; Shigella; Vibrio cholerae; Yersinia enterocolitica | 1993 |
A multicenter study on the comparative in vitro activity of fleroxacin and three other quinolones: an interim report from 27 centers.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1993 |
Proposed criteria for interpretation of susceptibilities of strains of Neisseria gonorrhoeae to ciprofloxacin, ofloxacin, enoxacin, lomefloxacin, and norfloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Diffusion; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Quinolones | 1995 |
Activity of CP 99,219 (trovafloxacin) compared with ciprofloxacin, sparfloxacin, clinafloxacin, lomefloxacin and cefuroxime against ten penicillin-susceptible and penicillin-resistant pneumococci by time-kill methodology.
Topics: Anti-Infective Agents; Cefuroxime; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Penicillin Resistance; Quinolones; Streptococcus pneumoniae | 1996 |
Detection of quinolone-resistant Neisseria gonorrhoeae.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Female; Fleroxacin; Fluoroquinolones; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Quinolones; Reference Standards | 1996 |
The photomutagenicity of fluoroquinolones in tests for gene mutation, chromosomal aberration, gene conversion and DNA breakage (Comet assay).
Topics: Animals; Anti-Infective Agents; Carcinogens; Chromosome Aberrations; Ciprofloxacin; Cricetinae; DNA Damage; Fleroxacin; Fluoroquinolones; Gene Conversion; Lymphoma; Methoxsalen; Mice; Mitosis; Mutagenicity Tests; Mutagens; Mutation; Photosensitizing Agents; Quinolones; Saccharomyces cerevisiae; Salmonella; Tumor Cells, Cultured; Ultraviolet Rays | 1996 |
[Effect of drugs of the fluoroquinolone series on morphokinetic parameters of the cellular elements of lung tissue].
Topics: Animals; Anti-Infective Agents; Cell Division; Ciprofloxacin; Culture Techniques; Dogs; Fluoroquinolones; Guinea Pigs; Lung; Lymphocytes; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Ofloxacin; Quinolones | 1996 |
Fluoroquinolone antibacterials enhance UVA-induced skin tumors.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Female; Fleroxacin; Fluoroquinolones; Mice; Nalidixic Acid; Neoplasms, Radiation-Induced; Ofloxacin; Quinolones; Skin Neoplasms; Ultraviolet Rays | 1997 |
Quinolone antibacterials: a new class of photochemical carcinogens.
Topics: Animals; Anti-Infective Agents; Carcinoma, Squamous Cell; Ciprofloxacin; Dermatitis, Phototoxic; Fleroxacin; Fluoroquinolones; Methoxsalen; Mice; Mice, Hairless; Nalidixic Acid; Neoplasms, Radiation-Induced; Ofloxacin; Papilloma; Quinolones; Skin Neoplasms | 1997 |
[Use of fluoroquinolones in rheumatology].
Topics: Adolescent; Adult; Anti-Infective Agents; Ciprofloxacin; Drug Tolerance; Female; Fluoroquinolones; Follow-Up Studies; Humans; Male; Middle Aged; Pefloxacin; Quinolones; Rheumatic Diseases; Time Factors | 1996 |
Participation of reactive oxygen species in phototoxicity induced by quinolone antibacterial agents.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; DNA; DNA Damage; Enoxacin; Fluoroquinolones; Free Radical Scavengers; Hematoporphyrins; Molecular Structure; Ofloxacin; Oxygen; Photosensitizing Agents; Quinolones; Reactive Oxygen Species; Spectroscopy, Near-Infrared; Superoxides | 1997 |
Quinolone antibiotic photodynamic production of 8-oxo-7, 8-dihydro-2'-deoxyguanosine in cultured liver epithelial cells.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Infective Agents; Cell Line; Chromatography, High Pressure Liquid; Ciprofloxacin; Deoxyguanosine; Electrochemistry; Epithelial Cells; Epithelium; Fluoroquinolones; Liver; Photosensitizing Agents; Quinolones; Rats; Spectrophotometry, Ultraviolet | 1997 |
In vitro and in vivo antibacterial efficacies of CFC-222, a new fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Culture Media; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1997 |
In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pefloxacin; Quinolones; Respiratory Tract Infections | 1997 |
In-vitro and in-vivo antibacterial activity of CFC-222, a new fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1998 |
Photosensitivity induced by lomefloxacin with cross-photosensitivity to ciprofloxacin and fleroxacin.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Dermatitis, Photoallergic; Fleroxacin; Fluoroquinolones; Humans; Male; Quinolones | 1998 |
Effects of fluoroquinolones and magnesium deficiency in murine limb bud cultures.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; Extremities; Fleroxacin; Fluoroquinolones; Magnesium Deficiency; Mice; Microscopy, Electron; Ofloxacin; Pefloxacin; Quinolones | 1998 |
Comparison of the complexation of fluoroquinolone antimicrobials with metal ions by nuclear magnetic resonance spectroscopy.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Levofloxacin; Magnetic Resonance Spectroscopy; Metals; Ofloxacin; Quinolones; Solutions; Temperature | 1999 |
In vitro phototoxicity of new quinolones: production of active oxygen species and photosensitized lipid peroxidation.
Topics: Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; DNA Damage; Fleroxacin; Fluoroquinolones; Humans; Lipid Peroxidation; Norfloxacin; Ofloxacin; Quinolones; Reactive Oxygen Species; Squalene; Time Factors; Ultraviolet Rays | 1999 |
Comparative studies on topical lomefloxacin and ciprofloxacin on ocular kinetic and experimental corneal ulcer.
Topics: Administration, Topical; Animals; Anti-Infective Agents; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Corneal Ulcer; Eye; Female; Fluoroquinolones; Hydrogen-Ion Concentration; Male; Quinolones; Rabbits; Staphylococcal Infections; Staphylococcus aureus | 1999 |
[The chemotherapeutic efficacy of ciprofloxacin and lomefloxacin in the inhalation method of infecting white mice with tularemia].
Topics: Aerosols; Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; Drug Evaluation, Preclinical; Fluoroquinolones; Mice; Particle Size; Quinolones; Research Design; Tularemia | 2000 |
A thermodynamic study of complexation of ciprofloxacin and lomefloxacin with aluminium ion.
Topics: Aluminum; Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Drug Stability; Entropy; Fluoroquinolones; Quinolones; Thermodynamics | 2000 |
Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones.
Topics: Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Cytoplasm; Fibroblasts; Fluoroquinolones; Humans; Mitochondria; Norfloxacin; Ofloxacin; Photosensitizing Agents; Quinolones; Skin | 2000 |
Lomefloxacin is an effective treatment of experimental bacterial keratitis.
Topics: Administration, Topical; Animals; Anti-Infective Agents; Bacteria; Ciprofloxacin; Colony Count, Microbial; Corneal Stroma; Drug Evaluation, Preclinical; Eye Infections, Bacterial; Fluoroquinolones; Keratitis; Microbial Sensitivity Tests; Models, Animal; Ophthalmic Solutions; Quinolones; Rabbits | 2001 |
Simple high-performance liquid chromatographic assay for the determination of ciprofloxacin in human plasma with ultraviolet detection.
Topics: Anti-Infective Agents; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Humans; Molecular Structure; Quinolones; Reproducibility of Results | 2001 |
[Degradation of liquid preparations of four fluoroquinolones by factorial experiment. ].
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Light; Norfloxacin; Ofloxacin; Quinolones | 1997 |
Accumulation of ciprofloxacin and lomefloxacinin fluoroquinolone-resistant strains of Escherichia coli.
Topics: 2,4-Dinitrophenol; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Porins; Quinolones | 2002 |
[Phototoxicity studies of pazufloxacin mesilate, a novel parenteral quinolone antimicrobial agent--in vitro and in vivo studies].
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Female; Fluoroquinolones; Guinea Pigs; Nalidixic Acid; Ofloxacin; Oxazines; Quinolones; Rats; Rats, Sprague-Dawley; Ultraviolet Rays | 2002 |
[Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration].
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; beta-Alanine; Biphenyl Compounds; Cefazolin; Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Convulsants; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Imipenem; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Norfloxacin; Oxazines; Penicillin G; Quinolones; Seizures; Thienamycins | 2002 |
Reliability of phototoxic tests of fluoroquinolones in vitro.
Topics: 3T3 Cells; Animals; Anti-Infective Agents; Ciprofloxacin; Cricetinae; Cricetulus; Dermatitis, Phototoxic; Female; Fluoroquinolones; Mice; Mice, Inbred BALB C; Micronucleus Tests; Norfloxacin; Quinolones; Rats; Rats, Wistar; Ultraviolet Rays | 2003 |
In vitro and in vivo activities of fluoroquinolones against Aeromonas hydrophila.
Topics: Aeromonas hydrophila; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Cefotaxime; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacterial Infections; Humans; In Vitro Techniques; Levofloxacin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Ofloxacin; Quinolines; Quinolones | 2003 |
Binding characteristics of fluoroquinolones to synthetic levodopa melanin.
Topics: Binding Sites; Chloroquine; Ciprofloxacin; Drug Interactions; Enoxacin; Fluoroquinolones; Levodopa; Levofloxacin; Melanins; Monophenol Monooxygenase; Norfloxacin; Ofloxacin; Quinolones; Timolol | 2003 |
[Analysis of the response factors of different quinolones detected by evaporative light-scattering detector].
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Light; Linear Models; Ofloxacin; Quinolones | 2003 |
Compare two methods of measuring DNA damage induced by photogenotoxicity of fluoroquinolones.
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Comet Assay; Cricetinae; Cricetulus; DNA; DNA Damage; Fibroblasts; Fluoroquinolones; Levofloxacin; Ofloxacin; Quinolones; Ultraviolet Rays | 2004 |
[Simultaneous determination of quinolones in foods by LC/MS/MS].
Topics: Animals; Chromatography, Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fishes; Fluoroquinolones; Food Analysis; Meat; Ofloxacin; Quinolones; Spectrometry, Mass, Electrospray Ionization | 2004 |
Vibrational spectroscopic characterization of fluoroquinolones.
Topics: Aza Compounds; Cinoxacin; Ciprofloxacin; DNA Gyrase; DNA, Bacterial; Enoxacin; Enzyme Inhibitors; Fluoroquinolones; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Chemical; Models, Molecular; Models, Theoretical; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxolinic Acid; Quinolines; Quinolones; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Temperature; Ultraviolet Rays; Vibration; Water | 2005 |
In vitro activity of fluoroquinolones against Mycobacterium tuberculosis.
Topics: Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Quinolones; Sampling Studies; Sensitivity and Specificity | 2005 |
The simultaneous separation and determination of five quinolone antibiotics using isocratic reversed-phase HPLC: application to stability studies on an ofloxacin tablet formulation.
Topics: Anti-Bacterial Agents; Calibration; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Industry; Drug Stability; Fluoroquinolones; Hydrogen-Ion Concentration; Models, Chemical; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones; Reproducibility of Results; Tablets; Time Factors | 2005 |
T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antigen-Presenting Cells; Aza Compounds; Cell Proliferation; Cells, Cultured; Ciprofloxacin; Clone Cells; Cross Reactions; Drug Hypersensitivity; Enoxacin; Female; Fluoroquinolones; Humans; Hypersensitivity, Delayed; Middle Aged; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Patch Tests; Pipemidic Acid; Quinolines; Quinolones; T-Lymphocytes | 2006 |
Selective action of fluoroquinolones against intracellular amastigotes of Leishmania (Viannia) panamensis in vitro.
Topics: Animals; Cell Line; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Leishmania guyanensis; Macrophages; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones | 2005 |
Penetration of second-, third-, and fourth-generation topical fluoroquinolone into aqueous and vitreous humour in a rabbit endophthalmitis model.
Topics: Animals; Anti-Bacterial Agents; Aqueous Humor; Aza Compounds; Ciprofloxacin; Disease Models, Animal; Endophthalmitis; Eye Infections, Bacterial; Fluoroquinolones; Levofloxacin; Moxifloxacin; Ofloxacin; Ophthalmic Solutions; Quinolines; Rabbits; Staphylococcal Infections; Vitreous Body | 2007 |
Photo-chemically induced DNA effects in the comet assay with epidermal cells of SKH-1 mice after a single oral administration of different fluoroquinolones and 8-methoxypsoralen in combination with exposure to UVA.
Topics: Administration, Oral; Animals; Cells, Cultured; Ciprofloxacin; Comet Assay; DNA; DNA Damage; Epidermal Cells; Epidermis; Fluoroquinolones; Male; Methoxsalen; Mice; Mice, Hairless; Quinolones; Ultraviolet Rays | 2006 |
Adsorption and oxidation of fluoroquinolone antibacterial agents and structurally related amines with goethite.
Topics: Absorption; Anti-Bacterial Agents; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Iron Compounds; Kinetics; Minerals; Molecular Structure; Norfloxacin; Ofloxacin; Oxidation-Reduction | 2007 |
Separation of seven fluoroquinolones by microemulsion electrokinetic chromatography and application to ciprofloxacin, lomefloxacin determination in urine.
Topics: Chromatography, Micellar Electrokinetic Capillary; Ciprofloxacin; Fluoroquinolones; Humans; Reproducibility of Results | 2007 |
[Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry].
Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2007 |
Development and validation of a solid-phase extraction method coupled to liquid chromatography with fluorescence detection for the determination of fluoroquinolone residues in powdered infant formulae. Application to the analysis of samples from the Spani
Topics: Chromatography, Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Humans; Infant; Infant Formula; Latin America; Molecular Structure; Reproducibility of Results; Solid Phase Extraction; Spain; Spectrometry, Fluorescence | 2008 |
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Diclofenac; Dioxolanes; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Phenylacetates; Piperazines; Receptors, GABA-A; Seizures | 2009 |
Validation of a MLC method with fluorescence detection for the determination of quinolones in urine samples by direct injection.
Topics: Anti-Bacterial Agents; Aza Compounds; Calibration; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluorescence; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Reproducibility of Results | 2009 |
Development and validation of a fast isocratic liquid chromatography method for the simultaneous determination of norfloxacin, lomefloxacin and ciprofloxacin in human plasma.
Topics: Anti-Infective Agents; Chromatography, Liquid; Ciprofloxacin; Drug Stability; Fluoroquinolones; Humans; Levofloxacin; Linear Models; Norfloxacin; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity | 2011 |
[Preliminary study on occurrence and health risk assessment of quinolone antibiotics in vegetables from Guangzhou, China].
Topics: Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Food Contamination; Norfloxacin; Quinolones; Risk Assessment; Urban Health; Vegetables | 2010 |
Spectroscopic study of degradation products of ciprofloxacin, norfloxacin and lomefloxacin formed in ozonated wastewater.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Mass Spectrometry; Norfloxacin; Oxidation-Reduction; Ozone; Piperazine; Piperazines; Quinolones; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2012 |
Effect of diclofenac on ocular levels of ciprofloxacin and lomefloxacin in rabbits with endophthalmitis.
Topics: Administration, Topical; Animals; Anterior Eye Segment; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Diclofenac; Drug Interactions; Endophthalmitis; Fluoroquinolones; Microbial Sensitivity Tests; Rabbits; Staphylococcal Infections | 2014 |
Seeking the mechanism responsible for fluoroquinolone photomutagenicity: a pulse radiolysis, steady-state, and laser flash photolysis study.
Topics: Acetylation; Animals; Cattle; Ciprofloxacin; Deoxyguanosine; DNA; DNA Breaks, Single-Stranded; Fluoroquinolones; Kinetics; Lasers, Solid-State; Mutagens; Photolysis; Pulse Radiolysis; Solutions; Structure-Activity Relationship | 2014 |
Determination of five quinolone antibiotic residues in foods by micellar electrokinetic capillary chromatography with quantum dot indirect laser-induced fluorescence.
Topics: Animal Feed; Animals; Anti-Bacterial Agents; Cadmium Compounds; Chromatography, Micellar Electrokinetic Capillary; Ciprofloxacin; Enrofloxacin; European Union; Fluorescence; Fluoroquinolones; Hydrogen-Ion Concentration; Japan; Lasers; Limit of Detection; Loxapine; Norfloxacin; Quantum Dots; Quinolones; Spectrometry, Fluorescence; Tellurium | 2014 |
Structure-activity relationship and role of oxygen in the potential antitumour activity of fluoroquinolones in human epithelial cancer cells.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Hypoxia; Cell Line, Tumor; Ciprofloxacin; DNA Damage; Fluoroquinolones; HeLa Cells; Humans; Oxygen; Photosensitizing Agents; Plasmids; Singlet Oxygen; Structure-Activity Relationship; Ultraviolet Rays | 2014 |
[Contamination characteristics of fluoroquinolones in different kinds of soil profiles in Southeast suburb of Beijing].
Topics: Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; Ciprofloxacin; Cities; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Soil; Soil Pollutants | 2014 |
Simultaneous separation/enrichment and detection of trace ciprofloxacin and lomefloxacin in food samples using thermosensitive smart polymers aqueous two-phase flotation system combined with HPLC.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Food; Food Analysis; Polymers | 2016 |
[Development of Determination Method of Fluoroquinolone Antibiotics in Sludge Based on Solid Phase Extraction and HPLC-Fluorescence Detection Analysis].
Topics: Adsorption; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluorescence; Fluoroquinolones; Norfloxacin; Ofloxacin; Sewage; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical | 2016 |
Effect of fluoroquinolones on melanogenesis in normal human melanocytes HEMn-DP: a comparative in vitro study.
Topics: Anti-Bacterial Agents; Cell Line; Cell Survival; Ciprofloxacin; Dermatitis, Phototoxic; Epidermal Cells; Epidermis; Fluoroquinolones; Humans; Melanins; Melanocytes; Monophenol Monooxygenase; Moxifloxacin; Spectrophotometry | 2017 |