ciprofloxacin and linezolid

ciprofloxacin has been researched along with linezolid in 145 studies

Research

Studies (145)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's47 (32.41)29.6817
2010's75 (51.72)24.3611
2020's23 (15.86)2.80

Authors

AuthorsStudies
Inagaki, H; Kawakami, K; Kawato, HC; Matsuhashi, N; Miyauchi, RN; Miyauchi, S; Ohki, H; Takahashi, H; Takemura, M1
Banitt, LS; Barbachyn, MR; Evans, JM; Gage, JR; Gomez, M; Gordeev, MF; Hackbarth, C; Luehr, GW; Morin, SE; Parker, CN; Patel, DV; Trias, J; White, RJ; Zurenko, GE1
Baeschlin, DK; Borer, Y; Haefeli, S; Hubschwerlen, C; Locher, HH; Schroeder, S; Sigwalt, C; Specklin, JL1
Appelbaum, PC; Bhawsar, SB; Bozdogan, B; de Souza, NJ; Desai, VN; Deshpande, PK; Gupte, SV; Hooper, DC; Jacobs, MR; Jha, R; Khorakiwala, HF; Patel, MV; Shetty, N; Shukla, MC; Strahilevitz, J; Yeole, RD1
Bachand, B; Barnes, MH; Bethell, R; Brown, NC; Butler, MM; Cadilhac, C; Charron, S; Comstock, J; Dix, EJ; Foster, KA; Holm, KA; LaMarr, WA; Lamothe, S; Long, ZY; Manikowski, A; Motorina, I; Storer, R; Tarantino, PM; Wright, GE; Xu, WC; Zhi, C1
Eldridge, GR; Garo, E; Goering, MG; Hough, GW; Hu, JF; O'Neil-Johnson, M1
Duewelhenke, N; Eysel, P; Krut, O1
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S1
Bradbury, BJ; Buechter, DD; Cheng, J; Deshpande, M; Hashimoto, A; Lucien, E; Marlor, CW; Nelson, DM; Ou, Y; Pais, GC; Podos, SD; Pucci, MJ; Song, Y; Thanassi, JA; Thoma, CL; Wang, Q; Wiles, JA1
Bradbury, BJ; Buechter, DD; Cheng, J; Deshpande, M; Mushtaq, G; Podos, SD; Pucci, MJ; Thanassi, JA; Thoma, CL; Vigliotti, GA1
Cheung, A; Götz, F; Herbert, S; Meehl, M1
Jansen, WT; Milatovic, D; Verel, A; Verhoef, J1
Beceiro, A; Bou, G; Canle, D; Fernández, A; Lasa, I; Latasa, C; Mallo, S; Molina, F; Pérez, A; Pérez, S; Poza, M; Tomás, Mdel M; Villanueva, R1
Bryce, E; Gravel, D; Loeb, M; Louie, L; Matlow, A; McGeer, A; Mulvey, M; Ofner-Agostini, M; Simor, AE; Stuart, TL; Watt, C1
Andricopulo, AD; Moda, TL; Montanari, CA1
Baudry, PJ; DeCorby, M; Hoban, DJ; Johnson, J; Karlowsky, JA; Lagacé-Wiens, P; Laing, N; McCracken, M; Mulvey, MR; Nichol, KA; Tailor, F; Vashisht, R; Walkty, A; Weshnoweski, B; Wierzbowski, A; Zhanel, GG1
Chopra, I; Ingham, E; Miller, K; O'Neill, AJ; Wilcox, MH1
Castanheira, M; Deshpande, LM; DiPersio, J; Jones, RN; Mendes, RE; Saubolle, MA1
Lombardo, F; Obach, RS; Waters, NJ1
Benton, BM; Debabov, DV; Difuntorum, S; Krause, KM; Renelli, M; Wu, TX1
Brown, DL; Drusano, GL; Heine, HS; Kim, K; Kinzig-Schippers, M; Liu, W; Louie, A; Sörgel, F; VanScoy, B1
Bammert, GF; Banitt, LS; Barbachyn, MR; Boyle, TP; Bundy, GL; Dolak, LA; Ford, CW; Graber, DR; Hamel, JC; Han, F; Harris, DW; Hromockyj, AE; Hurd, AR; Kamilar, GM; Marotti, KR; Martin, GE; Miller, AA; Mott, JE; Munzner, JB; Palmer, JR; Ruble, JC; Seest, EP; Skepner, JE; Sweeney, MT; Zhong, WZ; Zurenko, GE1
Amsler, KM; Bush, K; Davies, TA; Jacobs, MR; Shang, W1
del Pozo, JL; Mandrekar, JN; Patel, R; Rouse, MS; Sampedro, MF; Steckelberg, JM1
Boyd, EA; Brown, D; Collins, I; Czaplewski, LG; East, SP; Fletcher, R; Gardiner, M; Haydon, DJ; Henstock, V; Ingram, P; Jones, C; Kennison, L; Noula, C; Rockley, C; Rose, V; Stokes, NR; Thomaides-Brears, HB; Ure, R; Whittaker, M1
Cui, L; Hiramatsu, K; Neoh, HM; Shoji, M1
Bell, JM; Biedenbach, DJ; Jones, RN; Sader, HS; Turnidge, JD1
Fritsche, TR; Jones, RN; Sader, HS1
Gikas, A; Psaroulaki, A; Spyridaki, I; Tselentis, Y; Vranakis, I1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Hafkin, B; Hoban, DJ; Kaplan, N; Karlowsky, JA; Zhanel, GG1
Gaillard, JL; Jackson, M; McDonnell, G; Niederweis, M; Skovierová, H; Svetlíková, Z1
Cheung, CM; Firestine, SM; Rybak, MJ; Vooturi, SK1
Inagaki, H; Ito, M; Kawakami, K; Matsuhashi, N; Miyauchi, R; Ohki, H; Takahashi, H; Takemura, M1
Arhin, FF; Draghi, DC; Moeck, G; Parr, TR; Pillar, CM; Sahm, DF1
Adibpour, N; Khalaj, A; Rajabalian, S1
Miller, MJ; Möllmann, U; Wencewicz, TA; Yan, S1
Chen, HC; King, CH; Lai, JF; Lauderdale, TL; Shiau, YR1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Duan, Y; Hu, W; Li, M; Qian, Y; Shi, W; Yang, L1
Dai, L; Huang, SY; Li, BB; Shen, JZ; Wang, MG; Wang, Y; Wu, CM; Xia, LN1
Barrow, EW; Barrow, WW; Berlin, KD; Bourne, CR; Bourne, PC; Bunce, RA1
Bohnert, JA; Karamian, B; Nikaido, H1
Bavari, S; Bowlin, TL; Butler, MM; Moir, DT; Panchal, RG; Peet, NP; Shinabarger, DL; Williams, JD1
Chan, JL; Cheung, GY; Joo, HS; Otto, M1
Crandon, JL; Kuti, JL; Nicolau, DP1
Baek, SY; Chae, SE; Cho, YL; Jeong, JW; Jung, SJ; Kim, YZ; Kwak, JH; Lee, HH; Lee, HS; Park, TK; Woo, SH1
Adibpour, N; Faramarzi, MA; Firoozpour, L; Foroumadi, A; Khalaj, A; Nakhjiri, M; Negahbani, AS; Rajabalian, S; Samadi, N; Samadizadeh, M; Shafiee, A1
Aubart, K; Duan, Y; Fang, Y; Hu, W; Ma, H; Shi, W; Yang, L; Zonis, R1
Bradbury, BJ; Deshpande, M; Hashimoto, A; Kim, HY; Lucien, E; Nelson, DM; Pais, GC; Podos, SD; Pucci, MJ; Thanassi, JA; Wang, Q; Wiles, JA1
Bradbury, BJ; Deshpande, M; Phadke, AS; Pucci, MJ; Thanassi, JA; Wiles, JA1
Barnes, MH; Brown, NC; Butler, MM; Dvoskin, S; Gambino, JJ; Long, ZY; Wright, GE; Xu, WC; Zhi, CX1
Engels, JW; Grünewald, C; Krim, J; Taourirte, M1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Faazil, S; Hussaini, SM; Jagadeesh Babu, N; Kamal, A; Khan, IA; Kumar, CG; Narender Reddy, G; Poornachandra, Y; Rajput, VS; Rani, C; Sharma, R1
Anwar, M; Jeong, YC; Moloney, MG1
Hu, W; Lv, F; Shi, W; Xing, D; Yang, L; Yang, S; Yang, Y; Zhao, Z1
Basarab, GS; Brassil, P; Doig, P; Galullo, V; Gowravaram, M; Haimes, HB; Kern, G; Kutschke, A; McNulty, J; Schuck, VJ; Stone, G1
Gade, WN; Khan, FA; Marathe, SD; Patil, RH; Sangshetti, JN; Shinde, DB1
Cook, JL; Deng, J; Fung, LW; Johnson, ME; Kim, A; Wolf, NM; Zhu, T1
Banerjee, A; Chakrapani, H; Lahiri, S; Malwal, SR; Pardeshi, KA; Rangarajan, R1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abouelhassan, Y; Bai, F; Burch, GM; Garrison, AT; Huigens, RW; Jin, S; Kallifidas, D; Luesch, H; Nguyen, MT; Norwood, VM; Rolfe, M1
Miller, MJ; Möollmann, U; Wencewicz, TA; Yan, S1
Steenbergen, J; Tanaka, SK; Villano, S1
Brozovic, A; Dowson, CG; Gazvoda, M; Košmrlj, J; Lloyd, A; Osmak, M; Proud, C; Roper, DI; Vajs, J1
Kulkarni, MR; Lad, NP; Manohar, Y; Mascarenhas, M; Pandit, SS; Pandit, YB; Salkar, K; Sharma, R; Suthar, A1
Brönstrup, M; Dogonadze, M; Kantin, G; Karge, B; Krasavin, M; Manicheva, O; Parchinsky, V; Vinogradova, T1
Blumstein, AC; Bruyère, T; Bur, D; Chambovey, A; Ertel, EA; Gude, M; Hubschwerlen, C; Jacob, L; Kimmerlin, T; Panchaud, P; Pfeifer, T; Prade, L; Ritz, D; Rueedi, G; Seiler, P1
Abutaleb, NS; Dayal, N; Mohammad, H; Naclerio, GA; Opoku-Temeng, C; Seleem, MN; Sintim, HO1
Bi, F; Cai, X; Gu, X; Hu, C; Liu, Z; Ma, S; Song, D; Venter, H; Zhang, N1
Ameryckx, A; Frédérick, R; Joris, B; Leimanis, S; Pochet, L; Poupaert, JH; Thabault, L; Van Bambeke, F; Wouters, J1
Eswaran, S; Narayanan, S; Shivarudraiah, P; Shruthi, TG; Subramanian, S1
Guo, H1
Cruz, CD; Draskovits, G; Durcik, M; Ilaš, J; Kikelj, D; Mašič, LP; Nyerges, Á; Pál, C; Révész, T; Skok, Ž; Tammela, P; Tiz, DB; Tomašič, T; Zega, A; Zidar, N; Žigon, D1
Bi, F; Liu, X; Ma, S; Qin, Y; Song, D; Teng, Y; Zhang, N; Zhang, P1
Ameryckx, A; Frédérick, R; Pochet, L; Saadi, BE; Van Bambeke, F; Wang, G; Wouters, J; Yildiz, E1
Abutaleb, NS; Alhashimi, M; Kassab, AE; Mayhoub, AS; Mohamed, KO; Seleem, MN; Shahin, IG; Taher, AT1
Amada, H; Endo, M; Hitaka, K; Kamitani, M; Masuko, A; Mihara, Y; Mima, M; Ohtake, N; Sugiyama, H; Takata, I; Takeuchi, T; Tamura, Y; Tanaka-Yamamoto, N; Ushiyama, F; Wada, R1
Bi, F; Liu, X; Ma, S; Qin, Y; Song, D; Teng, Y; Zhang, N1
Cruz, CD; Ghemtio, L; Heikkinen, S; Iashin, V; Mäkkylä, H; Moslova, K; Perea-Buceta, JE; Tammela, P; Wrigstedt, P1
Alam, MA; Basnakian, AG; Frangie, MM; Gilmore, DF; Hansa, RK; Khan, MMK; Savenka, AV; Shelton, RS; Shuttleworth, SL; Smeltzer, MS1
Abouelhassan, Y; Chojnacki, M; Ding, Y; Dunman, PM; Fuse, MA; Huang, G; Huigens, RW; Jin, S; Kallifidas, D; Kundra, S; Lemos, JA; Liu, K; Luesch, H; Rohde, KH; Yang, H; Zhang, P1
Chen, W; Gu, X; Guo, T; Ma, S; Song, D; Zhang, L; Zhang, N; Zhang, P1
Chen, W; Ma, S; Song, D; Zhang, N; Zhang, P; Zhang, S1
Abugazleh, MK; Alam, MA; Ali, H; Gilmore, D; Raj Kc, H; Roy, S; Saleh, I1
Dayal, N; Onyedibe, KI; Sintim, HO1
Bora, A; Deka, B; Devi, MV; Dihingia, A; Pahari, P; Sarma, S; Sen, T; Singh, AK; Suri, M1
Trissel, LA; Williams, KY; Xu, QA; Zhang, Y1
Georgopoulos, A; Graninger, W; Grisold, A; Mueller-Uri, P; Presterl, E1
Grohs, P; Gutmann, L; Kitzis, MD1
Kinzig-Schippers, M; Naber, KG; Onda, H; Sörgel, F; Wagenlehner, FM; Wydra, S1
Aktaş, E; Ayyildiz, A; Ertek, M; Parlak, M; Yazgi, H1
Bergiers, C; Derue, G; Dujardin, JP; Frippiat, F; Michel, C1
Cirioni, O; De Fusco, M; Ghiselli, R; Giacometti, A; Licci, A; Mocchegiani, F; Orlando, F; Provinciali, M; Saba, V; Scalise, G; Silvestri, C1
Anguita-Alonso, P; Jacofsky, DJ; Osmon, DR; Patel, R; Piper, KE; Rouse, MS1
Bedenic, B; Bubonja, M; Budimir, A; Topic, M1
Jackson, MA; Selvarangan, R; Sharma, M; Thorell, EA; Woods, GM1
Blanes, M; Morales, P; Pérez-Enguix, D; Ros, JA; Saiz, V; Santos, M1
Knorr, JP; Moshfeghi, M; Sokoloski, MC1
Jones, NP1
Bossaer, JB; Garrett-Mayer, E; Hall, PD1
Johnson, AJ; Marker, DR; Martin, J; Mont, MA; Stroh, DA; Zywiel, MG1
Fajardo Olivares, M; Hidalgo Orozco, R; Robles Marcos, M; Rodríguez Garrido, S; Rodríguez-Vidigal, FF; Vera Tomé, A1
Abshire, T; Brown, DL; Drusano, GL; Heine, HS; Holman, K; Kulawy, R; Liu, W; Louie, A; Vanscoy, BD1
Eriguchi, Y; Harada, Y; Kadowaki, M; Miyake, N; Nagasaki, Y; Sato, Y; Shimono, N; Uchida, Y1
Holmberg, A; Mörgelin, M; Rasmussen, M1
Brown, DL; Drusano, GL; Heine, HS; Kulawy, RW; Louie, A; VanScoy, BD1
George, D; Gibson, G; Hardink, J; Lamb, L; Marra, A; Medina, I; O'Donnell, JP; Rugg, J; Van Deusen, J1
Bogomolova, NS; Bol'shakov, LV; Kuznetsova, SM; Parshin, VD; Vishnevskaia, GA1
Ishii, F; Shimokawa, K; Takakuwa, R; Wada, Y; Yamazaki, N1
Escribano, JA; Lozano, J; Rivin, E; Solivera, J; Vidal, E1
Chopin, MC; Faure, K; Flateau, C; Guery, B; Harent, S; Vuotto, F; Wallet, F1
Mansouri, S; Sadeghi, J1
Frey, L; Maier, B; Suhr, A; Teupser, D; Vogeser, M; Zander, J; Zoller, M1
Caleffi-Ferracioli, KR; Canezin, PH; Cardoso, RF; Castilho, AL; de Lima Scodro, RB; Dias Siqueira, VL1
Bergeron, MG; Dridi, B; Leprohon, P; Lupien, A; Ouellette, M1
Amemoto, Y; Aoyama, T; Arakawa, S; Deguchi, T; Egawa, S; Fujimoto, Y; Fujisawa, M; Goto, H; Hamasuna, R; Hanaki, H; Hashimura, T; Hayami, H; Hirose, T; Ichikawa, T; Inatomi, H; Ishihara, S; Ishikawa, K; Ishitoya, S; Ito, N; Ito, T; Iwata, S; Kadota, J; Kagara, I; Kaku, M; Kanamaru, S; Kato, M; Kawanishi, H; Kimura, T; Kiyota, H; Kobayashi, K; Kobuke, M; Koda, S; Komeda, H; Kumon, H; Kunishima, Y; Maeda, H; Matsubara, A; Matsuda, Y; Matsui, T; Matsukawa, M; Matsumoto, M; Matsumoto, T; Minamitani, S; Mita, K; Mitsumori, K; Muranaka, T; Nakamura, I; Nishimura, K; Oka, H; Okumura, K; Onishi, H; Onodera, S; Sato, J; Shigeta, M; Sunakawa, K; Taguchi, K; Takahashi, K; Takahashi, S; Takahashi, Y; Takenaka, T; Tanaka, K; Togo, Y; Tsugawa, M; Tsukamoto, T; Uehara, S; Wakeda, H; Watanabe, A; Yamada, D; Yamamoto, S; Yamashita, M; Yasuda, M1
Altboum, Z; Bar-David, E; Glinert, I; Kobiler, D; Levy, H; Schlomovitz, J; Sittner, A; Weiss, S1
Hamad, T; Hellmark, B; Nilsdotter-Augustinsson, Å; Söderquist, B1
Jung, JA; Kaisar, N; Parvez, MM; Shin, HJ; Shin, JG1
Desai, S; Nair, S; Poonacha, N; Sharma, U; Vipra, A1
Bouziane, F; Cambau, E; Chau, F; Crockett, F; Mougari, F; Nessar, R; Raskine, L; Sapriel, G; Veziris, N1
Carlucci, G; Carlucci, M; Cichella, A; Cotellese, R; Ferrone, V; Marco, LD; Raimondi, P1
Carlucci, G; Carlucci, M; Cichella, A; Cotellese, R; Di Marco, L; Ferrone, V; Genovese, S; Raimondi, P1
Cosentini, E; Eberl, S; Jäger, W; Jaros, D; Poschner, S; Schwameis, R; Wulkersdorfer, B; Zeitlinger, M1
Hsieh, TC; Hsueh, PR; Jean, SS; Ning, YZ1
Amiyangoda, CGK; Bowatte, S; Wimalaratna, H1
Arthur, M; Compain, F; Dorchène, D; Dubée, V; Gaillard, JL; Herrmann, JL; Heym, B; Soroka, D1
Bar-David, E; Ben-Shmuel, A; Brosh, T; Glinert, I; Kobiler, D; Levy, H; Schlomovitz, J; Sittner, A; Weiss, S1
Holzknecht, BJ; Justesen, US; Lund, LC1
García Callejo, J1
Choi, MJ; Hyun, BH; Jung, DY; Kang, HY; Lim, SK; Moon, DC; Na, SH; Oh, SJ1
Epps, KL; Epps, QJ; Young, DC; Zobell, JT1
Cruz, CD; Esteve, P; Tammela, P1
Goto, K; Itoh, H; Kai, M; Kitano, T; Ohchi, Y; Suzuki, Y; Tanaka, R; Tatsuta, R; Yasuda, N2
Dos Santos, LDR; Furlan, JPR; Gallo, IFL; Ramos, MS; Savazzi, EA; Stehling, EG1
Buszewski, B; Król-Górniak, A; Pauter, K; Pomastowski, P; Szultka-Młyńska, M; Szumski, M1
Abdulla, A; Bos, K; de Winter, BCM; Koch, BCP; Muller, AE; Oosterhoff, M; van Oldenrijk, J; Zhao, Q1
Abd Algaffar, SO; Khalid, SA; van de Sande, WWJ; Verbon, A1
Ölmez, S; Otlu, B; Sancak, B; Şener, B1
Arslan, N; Esen, N; Özkarataş, MH; Özkütük, AA1
Alorabi, M; Ejaz, U; Khoso, BK; Mahmoud, SF; Sohail, M; Uddin, F; Youssef, M1

Reviews

7 review(s) available for ciprofloxacin and linezolid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Discovery, pharmacology, and clinical profile of omadacycline, a novel aminomethylcycline antibiotic.
    Bioorganic & medicinal chemistry, 2016, 12-15, Volume: 24, Issue:24

    Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Drug Discovery; Humans; Microbial Sensitivity Tests; Molecular Conformation; Tetracyclines

2016
Isatin derivatives and their anti-bacterial activities.
    European journal of medicinal chemistry, 2019, Feb-15, Volume: 164

    Topics: Anti-Bacterial Agents; Bacteria; Humans; Isatin; Structure-Activity Relationship

2019
Role of vancomycin in the treatment of bacteraemia and meningitis caused by Elizabethkingia meningoseptica.
    International journal of antimicrobial agents, 2017, Volume: 50, Issue:4

    Topics: Anti-Bacterial Agents; Bacteremia; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; Drug Synergism; Drug Therapy, Combination; Flavobacteriaceae; Flavobacteriaceae Infections; Humans; Immunocompromised Host; Infant, Low Birth Weight; Infant, Newborn; Linezolid; Meningitis, Bacterial; Rifampin; Treatment Outcome; Vancomycin

2017
[Treatment of vancomycin-resistant enterococcal infections].
    Ugeskrift for laeger, 2018, Apr-16, Volume: 180, Issue:16

    Topics: Anti-Bacterial Agents; Bacteremia; Ciprofloxacin; Daptomycin; Denmark; Drug Therapy, Combination; Gram-Positive Bacterial Infections; Humans; Linezolid; Nitrofurantoin; Tigecycline; Urinary Tract Infections; Vancomycin-Resistant Enterococci

2018
State of the art in cystic fibrosis pharmacology-Optimization of antimicrobials in the treatment of cystic fibrosis pulmonary exacerbations: I. Anti-methicillin-resistant Staphylococcus aureus (MRSA) antibiotics.
    Pediatric pulmonology, 2020, Volume: 55, Issue:1

    Topics: Aminoglycosides; Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Ciprofloxacin; Clindamycin; Cystic Fibrosis; Humans; Linezolid; Lipoglycopeptides; Methicillin; Methicillin-Resistant Staphylococcus aureus; Rifampin; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin

2020
The mysteries of target site concentrations of antibiotics in bone and joint infections: what is known? A narrative review.
    Expert opinion on drug metabolism & toxicology, 2022, Volume: 18, Issue:9

    Topics: Anti-Bacterial Agents; Cefazolin; Cefuroxime; Ciprofloxacin; Humans; Linezolid; Microbial Sensitivity Tests; Vancomycin

2022

Trials

2 trial(s) available for ciprofloxacin and linezolid

ArticleYear
In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9

    Topics: Anti-Bacterial Agents; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Skin Diseases, Bacterial; Staphylococcus

2008
Concentrations in plasma, urinary excretion, and bactericidal activity of linezolid (600 milligrams) versus those of ciprofloxacin (500 milligrams) in healthy volunteers receiving a single oral dose.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:12

    Topics: Acetamides; Adult; Anti-Infective Agents; Area Under Curve; Bacteria; Calibration; Cephalosporins; Ciprofloxacin; Cross-Over Studies; Double-Blind Method; Female; Half-Life; Humans; Hydrogen-Ion Concentration; Linezolid; Male; Oxazolidinones; Quality Control; Serum Bactericidal Test

2003

Other Studies

136 other study(ies) available for ciprofloxacin and linezolid

ArticleYear
Synthesis and structure-activity relationships of 5-amino-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-8-methylquinolonecarboxylic acid antibacterials having fluorinated 7-[(3R)-3-(1-aminocyclopropan-1-yl)pyrrolidin-1-yl] substituents.
    Journal of medicinal chemistry, 2003, Mar-13, Volume: 46, Issue:6

    Topics: Anti-Bacterial Agents; Cyclopropanes; Drug Resistance, Bacterial; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quinolones; Stereoisomerism; Structure-Activity Relationship

2003
Novel oxazolidinone-quinolone hybrid antimicrobials.
    Bioorganic & medicinal chemistry letters, 2003, Dec-01, Volume: 13, Issue:23

    Topics: Acetamides; Anti-Bacterial Agents; Ciprofloxacin; DNA Topoisomerase IV; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Quinolones; Structure-Activity Relationship

2003
Structure-activity relationship in the oxazolidinone-quinolone hybrid series: influence of the central spacer on the antibacterial activity and the mode of action.
    Bioorganic & medicinal chemistry letters, 2003, Dec-01, Volume: 13, Issue:23

    Topics: Acetamides; Anti-Bacterial Agents; DNA Topoisomerase IV; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Quinolones; Structure-Activity Relationship

2003
A chiral benzoquinolizine-2-carboxylic acid arginine salt active against vancomycin-resistant Staphylococcus aureus.
    Journal of medicinal chemistry, 2005, Aug-11, Volume: 48, Issue:16

    Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Clinical Trials, Phase I as Topic; Dogs; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Half-Life; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Mutation; Prodrugs; Quinolizines; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship; Vancomycin Resistance

2005
Hybrid antibacterials. DNA polymerase-topoisomerase inhibitors.
    Journal of medicinal chemistry, 2006, Feb-23, Volume: 49, Issue:4

    Topics: Aniline Compounds; Animals; Anti-Bacterial Agents; DNA Polymerase III; Drug Resistance, Bacterial; Gram-Positive Bacteria; Male; Mice; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship; Topoisomerase II Inhibitors; Toxicity Tests, Acute; Uracil

2006
Antibacterial, partially acetylated oligorhamnosides from Cleistopholis patens.
    Journal of natural products, 2006, Volume: 69, Issue:4

    Topics: Annonaceae; Anti-Bacterial Agents; Gabon; Glycosides; Methicillin Resistance; Molecular Structure; Plant Leaves; Plants, Medicinal; Staphylococcus aureus

2006
Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Antimycin A; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Chloramphenicol; Clindamycin; Dose-Response Relationship, Drug; Fluoroquinolones; Glycolysis; HeLa Cells; Humans; Lactic Acid; Linezolid; Macrolides; Mitochondria; Osteoblasts; Oxazolidinones; Rotenone; Tetracyclines; Time Factors

2007
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen

2007
Isothiazoloquinolones with enhanced antistaphylococcal activities against multidrug-resistant strains: effects of structural modifications at the 6-, 7-, and 8-positions.
    Journal of medicinal chemistry, 2007, Jan-25, Volume: 50, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Cell Line, Tumor; Drug Resistance, Multiple, Bacterial; Female; Humans; Methicillin Resistance; Mice; Quinolones; Staphylococcus aureus; Structure-Activity Relationship; Thiazoles; Topoisomerase II Inhibitors

2007
In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Animals; Anti-Infective Agents; Drug Resistance, Bacterial; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Mice; Microbial Sensitivity Tests; Quinolones; Thiazoles

2007
Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8

    Topics: Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Bacterial Proteins; Gene Expression Regulation, Bacterial; Humans; Microbial Sensitivity Tests; Polymyxin B; Signal Transduction; Staphylococcal Infections; Staphylococcus aureus; Vancomycin; Vancomycin Resistance

2007
In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9

    Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Europe; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Lipoglycopeptides; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus; Streptococcus agalactiae; Streptococcus pyogenes; Vancomycin Resistance; Viridans Streptococci

2007
Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9

    Topics: Bacterial Proteins; Base Sequence; beta-Lactamases; Carrier Proteins; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Genes, MDR; Genetic Vectors; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Porins

2007
Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitals.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11

    Topics: Aged; Anti-Bacterial Agents; Canada; Cross Infection; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Female; Hospitals; Humans; Male; Methicillin Resistance; Microbial Sensitivity Tests; Mupirocin; Staphylococcal Infections; Staphylococcus aureus

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; beta-Lactamases; Canada; Drug Resistance, Bacterial; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Population Surveillance

2008
Delayed development of linezolid resistance in Staphylococcus aureus following exposure to low levels of antimicrobial agents.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6

    Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Culture Media; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fusidic Acid; Humans; Linezolid; Microbial Sensitivity Tests; Mutation; Oxazolidinones; Recombination, Genetic; Rifampin; RNA, Ribosomal, 23S; Staphylococcus aureus; Time Factors

2008
First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6

    Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; Drug Resistance, Bacterial; Humans; Linezolid; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Oxazolidinones; Sequence Analysis, DNA; Staphylococcal Infections; Staphylococcus aureus; Staphylococcus epidermidis

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
In vitro activity of telavancin against resistant gram-positive bacteria.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7

    Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; In Vitro Techniques; Lipoglycopeptides; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus; Streptococcus

2008
Use of an in vitro pharmacodynamic model to derive a linezolid regimen that optimizes bacterial kill and prevents emergence of resistance in Bacillus anthracis.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7

    Topics: Acetamides; Anthrax; Anti-Bacterial Agents; Bacillus anthracis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Bacterial; Humans; In Vitro Techniques; Linezolid; Models, Biological; Monte Carlo Method; Mutation; Oxazolidinones

2008
Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Bacteria; Bacterial Infections; Bacterial Proteins; Cell Line; Cell Proliferation; Metabolic Clearance Rate; Mice; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Stereoisomerism; Topoisomerase II Inhibitors

2008
Effect of electrical current on the activities of antimicrobial agents against Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis biofilms.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Anti-Infective Agents; Biofilms; Bioreactors; Electricity; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus; Staphylococcus epidermidis

2009
Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ.
    Bioorganic & medicinal chemistry letters, 2009, Jan-15, Volume: 19, Issue:2

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Benzamides; Cytoskeletal Proteins; Microbial Sensitivity Tests; Staphylococcus; Structure-Activity Relationship

2009
Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Chromosome Walking; DNA-Binding Proteins; Genetic Engineering; Genome, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Point Mutation; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Staphylococcus aureus; Vancomycin; Vancomycin Resistance

2009
Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Anti-Bacterial Agents; Asia; Drug Resistance, Bacterial; Europe; Gram-Positive Bacteria; Humans; Latin America; Microbial Sensitivity Tests; North America; Pacific Ocean; Quality Control; Teicoplanin; Vancomycin

2009
Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Topics: Anti-Bacterial Agents; Enterococcus faecalis; Europe; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Hospitalization; Humans; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pyrimidines; Staphylococcus aureus; Streptococcus; United States

2009
Bacteriostatic and bactericidal activities of tigecycline against Coxiella burnetii and comparison with those of six other antibiotics.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Chlorocebus aethiops; Coxiella burnetii; Humans; Microbial Sensitivity Tests; Minocycline; Q Fever; Tigecycline; Vero Cells

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8

    Topics: Anti-Bacterial Agents; Benzofurans; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enterobacteriaceae; Enterococcus; Microbial Sensitivity Tests; Moraxella catarrhalis; Pyrones; Staphylococcal Infections; Staphylococcus; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae

2009
Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Antitubercular Agents; Disinfectants; Drug Resistance, Bacterial; Glutaral; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Mycobacterium chelonae; Mycobacterium smegmatis; o-Phthalaldehyde; Porins

2009
Design, synthesis, and structure-activity relationships of benzophenone-based tetraamides as novel antibacterial agents.
    Journal of medicinal chemistry, 2009, Aug-27, Volume: 52, Issue:16

    Topics: Amides; Animals; Anti-Bacterial Agents; Benzophenones; Cell Membrane; Cell Wall; CHO Cells; Cricetinae; Cricetulus; DNA, Bacterial; Drug Design; Drug Resistance, Bacterial; Escherichia coli; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Protein Biosynthesis; RNA, Bacterial; Staphylococcus aureus; Structure-Activity Relationship

2009
Design, synthesis and biological evaluations of novel 7-[3-(1-aminocycloalkyl)pyrrolidin-1-yl]-6-desfluoro-8-methoxyquinolones with potent antibacterial activity against multi-drug resistant Gram-positive bacteria.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Anti-Bacterial Agents; Drug Design; Drug Resistance, Multiple; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quinolones; Structure-Activity Relationship

2009
Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11

    Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus faecium; Glycopeptides; Gram-Positive Bacteria; Humans; Lipoglycopeptides; Microbial Sensitivity Tests; Staphylococcus aureus; Streptococcus

2009
Synthesis and antibacterial activity of isothiazolyl oxazolidinones and analogous 3(2H)-isothiazolones.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Mice; Microbial Sensitivity Tests; NIH 3T3 Cells; Oxazolidinones; Thiazoles

2010
Syntheses and antibacterial activity studies of new oxazolidinones from nitroso Diels-Alder chemistry.
    Bioorganic & medicinal chemistry letters, 2010, Feb-01, Volume: 20, Issue:3

    Topics: Anti-Bacterial Agents; Gram-Positive Bacteria; Microbial Sensitivity Tests; Nitroso Compounds; Oxazolidinones

2010
Comparative in vitro activities of nemonoxacin (TG-873870), a novel nonfluorinated quinolone, and other quinolones against clinical isolates.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3

    Topics: Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Moxifloxacin; Quinolines; Quinolones; Taiwan

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Design, synthesis, and antibacterial activity of 2,5-dihydropyrrole formyl hydroxyamino derivatives as novel peptide deformylase inhibitors.
    Bioorganic & medicinal chemistry letters, 2010, Jun-15, Volume: 20, Issue:12

    Topics: Amidohydrolases; Amines; Anti-Bacterial Agents; Drug Design; Pyrroles; Structure-Activity Relationship

2010
First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Bacillus; Bacterial Proteins; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Feces; Lincosamides; Macrolides; Microbial Sensitivity Tests; Molecular Sequence Data; Streptogramin B; Swine

2010
Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Anti-Bacterial Agents; Enzyme Inhibitors; Inhibitory Concentration 50; Microbial Sensitivity Tests; Protein Structure, Secondary; Protein Structure, Tertiary; Staphylococcus aureus; Tetrahydrofolate Dehydrogenase

2010
Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Anti-Bacterial Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chlortetracycline; Dipeptides; Doxorubicin; Doxycycline; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Minocycline; Onium Compounds; Organophosphorus Compounds; Tetracycline

2010
Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Anti-Bacterial Agents; Gram-Negative Aerobic Bacteria; Gram-Positive Bacteria; Indoles; Microbial Sensitivity Tests

2010
Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Cytotoxins; Methicillin-Resistant Staphylococcus aureus; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Trans-Activators; Virulence

2010
Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Disease Models, Animal; Female; Lipoglycopeptides; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Pneumonia; Staphylococcal Infections; Vancomycin

2010
In vitro and in vivo activities of LCB01-0371, a new oxazolidinone.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12

    Topics: Acetamides; Animals; Anti-Bacterial Agents; Bacterial Infections; Gram-Positive Bacteria; Linezolid; Male; Mice; Mice, Inbred ICR; Oxazolidinones; Staphylococcus aureus; Vancomycin

2010
Discovery of a novel nitroimidazolyl-oxazolidinone hybrid with potent anti Gram-positive activity: Synthesis and antibacterial evaluation.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Drug Discovery; Gram-Positive Bacteria; Mice; NIH 3T3 Cells; Nitroimidazoles; Oxazolidinones

2011
Design, synthesis and antibacterial activity of 3-methylenepyrrolidine formyl hydroxyamino derivatives as novel peptide deformylase inhibitors.
    Bioorganic & medicinal chemistry letters, 2011, Feb-01, Volume: 21, Issue:3

    Topics: Amidohydrolases; Anti-Bacterial Agents; Drug Design; Drug Resistance, Bacterial; Enzyme Inhibitors; Haemophilus influenzae; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pyrrolidines

2011
Exploration of the activity of 7-pyrrolidino-8-methoxyisothiazoloquinolones against methicillin-resistant Staphylococcus aureus (MRSA).
    Journal of medicinal chemistry, 2011, May-12, Volume: 54, Issue:9

    Topics: Anti-Bacterial Agents; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Escherichia coli; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pyrrolidines; Quinolones; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Topoisomerase II Inhibitors

2011
Selenophene-containing inhibitors of type IIA bacterial topoisomerases.
    Journal of medicinal chemistry, 2011, May-12, Volume: 54, Issue:9

    Topics: Anti-Bacterial Agents; Cell Line, Tumor; DNA Topoisomerase IV; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Methicillin-Resistant Staphylococcus aureus; Organoselenium Compounds; Piperidines; Quinolines; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Topoisomerase II Inhibitors

2011
7-Alkyl-N(2)-substituted-3-deazaguanines. Synthesis, DNA polymerase III inhibition and antibacterial activity.
    Bioorganic & medicinal chemistry letters, 2011, Jul-15, Volume: 21, Issue:14

    Topics: Animals; Anti-Bacterial Agents; DNA Polymerase III; Enzyme Inhibitors; Escherichia coli; Gram-Positive Bacteria; Guanine; Mice; Microbial Sensitivity Tests; Staphylococcal Infections

2011
Efficient microwave-assisted synthesis, antibacterial activity and high fluorescence of 5 benzimidazolyl-2'-deoxyuridines.
    Bioorganic & medicinal chemistry, 2012, Jan-01, Volume: 20, Issue:1

    Topics: Anti-Bacterial Agents; Benzimidazoles; Catalysis; Deoxyuridine; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Microwaves; Sodium Bicarbonate; Spectrometry, Fluorescence

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Anti-tubercular agents. Part 8: synthesis, antibacterial and antitubercular activity of 5-nitrofuran based 1,2,3-triazoles.
    Bioorganic & medicinal chemistry letters, 2013, Dec-15, Volume: 23, Issue:24

    Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Cell Line; Cell Survival; Chlorocebus aethiops; Crystallography, X-Ray; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Conformation; Mycobacterium tuberculosis; Nitrofurans; Structure-Activity Relationship; Triazoles

2013
Synthesis, antibiotic activity and structure-activity relationship study of some 3-enaminetetramic acids.
    Bioorganic & medicinal chemistry letters, 2014, Apr-15, Volume: 24, Issue:8

    Topics: Anti-Bacterial Agents; Bacteria; Microbial Sensitivity Tests; Structure-Activity Relationship

2014
Synthesis, antibacterial activity, and biological evaluation of formyl hydroxyamino derivatives as novel potent peptide deformylase inhibitors against drug-resistant bacteria.
    European journal of medicinal chemistry, 2014, Oct-30, Volume: 86

    Topics: Amidohydrolases; Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Enzyme Inhibitors; Microbial Sensitivity Tests; Molecular Structure; Oligopeptides; Structure-Activity Relationship

2014
Novel DNA gyrase inhibiting spiropyrimidinetriones with a benzisoxazole scaffold: SAR and in vivo characterization.
    Journal of medicinal chemistry, 2014, Nov-13, Volume: 57, Issue:21

    Topics: Animals; Anti-Bacterial Agents; Barbiturates; Female; Fluoroquinolones; Heterocyclic Compounds, 4 or More Rings; Humans; Inhibitory Concentration 50; Isoxazoles; Male; Mice; Pyridones; Rats, Wistar; Spiro Compounds; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship; Topoisomerase II Inhibitors

2014
Biofilm inhibition of linezolid-like Schiff bases: synthesis, biological activity, molecular docking and in silico ADME prediction.
    Bioorganic & medicinal chemistry letters, 2015, Feb-15, Volume: 25, Issue:4

    Topics: Acetamides; Anti-Infective Agents; Biofilms; Computer Simulation; Linezolid; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Molecular Docking Simulation; Oxazolidinones; Schiff Bases

2015
Identification of Bacillus anthracis PurE inhibitors with antimicrobial activity.
    Bioorganic & medicinal chemistry, 2015, Apr-01, Volume: 23, Issue:7

    Topics: Anti-Infective Agents; Bacillus anthracis; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Protein Structure, Secondary; Protein Structure, Tertiary

2015
Thiol activated prodrugs of sulfur dioxide (SO2) as MRSA inhibitors.
    Bioorganic & medicinal chemistry letters, 2015, Jul-01, Volume: 25, Issue:13

    Topics: Anti-Bacterial Agents; Drug Design; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Prodrugs; Staphylococcal Infections; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfur Dioxide

2015
Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis.
    Journal of medicinal chemistry, 2016, 04-28, Volume: 59, Issue:8

    Topics: Biofilms; Carbon-13 Magnetic Resonance Spectroscopy; Drug Resistance, Bacterial; Drug Screening Assays, Antitumor; Halogens; HeLa Cells; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phenazines; Proton Magnetic Resonance Spectroscopy; Structure-Activity Relationship

2016
Syntheses and biological evaluation of new cephalosporin-oxazolidinone conjugates.
    MedChemComm, 2010, Aug-01, Volume: 1, Issue:2

    Topics:

2010
Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis.
    European journal of medicinal chemistry, 2017, Feb-15, Volume: 127

    Topics: Anti-Bacterial Agents; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mycobacterium smegmatis; Triazenes

2017
Methylsulfonyl benzothiazoles (MSBT) derivatives: Search for new potential antimicrobial and anticancer agents.
    Bioorganic & medicinal chemistry letters, 2017, 03-01, Volume: 27, Issue:5

    Topics: Anti-Infective Agents; Antineoplastic Agents; Bacteria; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Fungi; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Structure

2017
New nitrofurans amenable by isocyanide multicomponent chemistry are active against multidrug-resistant and poly-resistant Mycobacterium tuberculosis.
    Bioorganic & medicinal chemistry, 2017, 03-15, Volume: 25, Issue:6

    Topics: Antitubercular Agents; Carbon-13 Magnetic Resonance Spectroscopy; Cyanides; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitrofurans; Proton Magnetic Resonance Spectroscopy

2017
Discovery and Optimization of Isoquinoline Ethyl Ureas as Antibacterial Agents.
    Journal of medicinal chemistry, 2017, 05-11, Volume: 60, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Drug Discovery; Gram-Negative Bacteria; Half-Life; Hydrogen Bonding; Isoquinolines; Microbial Sensitivity Tests; Potassium Channels; Rats; Respiratory Tract Infections; Solubility; Urea

2017
N-(1,3,4-oxadiazol-2-yl)benzamide analogs, bacteriostatic agents against methicillin- and vancomycin-resistant bacteria.
    European journal of medicinal chemistry, 2018, Jul-15, Volume: 155

    Topics: Animals; Anti-Bacterial Agents; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Enterococcus faecalis; Gram-Positive Bacterial Infections; Methicillin; Mice; Microbial Sensitivity Tests; Molecular Structure; Skin Diseases, Bacterial; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin; Wound Infection

2018
Design, synthesis and structure-based optimization of novel isoxazole-containing benzamide derivatives as FtsZ modulators.
    European journal of medicinal chemistry, 2018, Nov-05, Volume: 159

    Topics: Anti-Bacterial Agents; Bacillus pumilus; Bacillus subtilis; Bacterial Proteins; Benzamides; Cell Survival; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Drug Design; HeLa Cells; Humans; Isoxazoles; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Structure-Activity Relationship

2018
1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio.
    European journal of medicinal chemistry, 2018, Nov-05, Volume: 159

    Topics: Anti-Bacterial Agents; Cell Survival; Dose-Response Relationship, Drug; Enterococcus faecalis; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Peptide Synthases; Semicarbazides; Staphylococcus aureus; Structure-Activity Relationship; THP-1 Cells

2018
Synthesis, antituberculosis studies and biological evaluation of new quinoline derivatives carrying 1,2,4-oxadiazole moiety.
    Bioorganic & medicinal chemistry letters, 2019, 01-01, Volume: 29, Issue:1

    Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Microsomes, Liver; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Quinolines; Structure-Activity Relationship

2019
An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: Amides; Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pyrrolidines; Topoisomerase II Inhibitors

2019
Discovery of 1,3,4-oxadiazol-2-one-containing benzamide derivatives targeting FtsZ as highly potent agents of killing a variety of MDR bacteria strains.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Bacterial Proteins; Benzamides; Cytoskeletal Proteins; Methicillin-Resistant Staphylococcus aureus

2019
Pharmacomodulations of the benzoyl-thiosemicarbazide scaffold reveal antimicrobial agents targeting d-alanyl-d-alanine ligase in bacterio.
    European journal of medicinal chemistry, 2020, Aug-15, Volume: 200

    Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia; Microbial Sensitivity Tests; Molecular Structure; Peptide Synthases; Staphylococcus aureus; Structure-Activity Relationship

2020
Evaluation of N-phenyl-2-aminothiazoles for treatment of multi-drug resistant and intracellular Staphylococcus aureus infections.
    European journal of medicinal chemistry, 2020, Sep-15, Volume: 202

    Topics: Animals; Anti-Bacterial Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Molecular Structure; Staphylococcal Infections; Structure-Activity Relationship; Thiazoles

2020
Lead optimization of 8-(methylamino)-2-oxo-1,2-dihydroquinolines as bacterial type II topoisomerase inhibitors.
    Bioorganic & medicinal chemistry, 2020, 11-15, Volume: 28, Issue:22

    Topics: Anti-Bacterial Agents; Cell Survival; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Hep G2 Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Quinolines; Streptococcus pneumoniae; Structure-Activity Relationship; Topoisomerase II Inhibitors; Transcriptional Regulator ERG; Vancomycin-Resistant Enterococci

2020
Design, synthesis of novel 4,5-dihydroisoxazole-containing benzamide derivatives as highly potent FtsZ inhibitors capable of killing a variety of MDR Staphylococcus aureus.
    Bioorganic & medicinal chemistry, 2020, 11-01, Volume: 28, Issue:21

    Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Benzamides; Binding Sites; Cell Survival; Cytoskeletal Proteins; Drug Design; Drug Resistance, Bacterial; Drug Stability; Gram-Negative Bacteria; Gram-Positive Bacteria; HeLa Cells; Humans; Isoxazoles; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Structure-Activity Relationship

2020
Installation of an aryl boronic acid function into the external section of N-aryl-oxazolidinones: Synthesis and antimicrobial evaluation.
    European journal of medicinal chemistry, 2021, Feb-05, Volume: 211

    Topics: Anti-Bacterial Agents; Boronic Acids; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Structure-Activity Relationship

2021
4-4-(Anilinomethyl)-3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-ylbenzoic acid derivatives as potent anti-gram-positive bacterial agents.
    European journal of medicinal chemistry, 2021, Jul-05, Volume: 219

    Topics: Aniline Compounds; Anti-Bacterial Agents; Biofilms; Cell Line; Cell Survival; Drug Resistance, Bacterial; Enterococcus faecalis; Gram-Positive Bacteria; Humans; Liver; Microbial Sensitivity Tests; Pyrazoles; Staphylococcus aureus; Structure-Activity Relationship

2021
A Modular Synthetic Route Involving
    Journal of medicinal chemistry, 2021, 06-10, Volume: 64, Issue:11

    Topics: Aniline Compounds; Animals; Anti-Bacterial Agents; Biofilms; Cell Line; Cell Survival; Disease Models, Animal; Drug Design; Female; Halogenation; Humans; Iron; Iron Deficiencies; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Phenazines; Staphylococcal Infections; Structure-Activity Relationship; Wound Healing

2021
Design, synthesis and evaluation of novel 9-arylalkyl-10-methylacridinium derivatives as highly potent FtsZ-targeting antibacterial agents.
    European journal of medicinal chemistry, 2021, Oct-05, Volume: 221

    Topics: Acridines; Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Drug Design; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Staphylococcus aureus; Structure-Activity Relationship

2021
Modification of 5-methylphenanthridium from benzothiazoles to indoles as potent FtsZ inhibitors: Broadening the antibacterial spectrum toward vancomycin-resistant enterococci.
    European journal of medicinal chemistry, 2021, Nov-15, Volume: 224

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Benzothiazoles; Cytoskeletal Proteins; Humans; Indoles; Molecular Structure; Phenanthridines; Structure-Activity Relationship; Vancomycin-Resistant Enterococci

2021
Design, synthesis, and antibacterial activity of
    RSC medicinal chemistry, 2021, Oct-20, Volume: 12, Issue:10

    Topics:

2021
SF
    RSC medicinal chemistry, 2021, Nov-17, Volume: 12, Issue:11

    Topics:

2021
Potentiating the intracellular killing of Staphylococcus aureus by dihydroquinazoline analogues as NorA efflux pump inhibitor.
    Bioorganic & medicinal chemistry, 2022, 01-15, Volume: 54

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Cell Survival; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Multidrug Resistance-Associated Proteins; Quinazolines; Staphylococcus aureus; Structure-Activity Relationship; THP-1 Cells

2022
Compatibility and stability of linezolid injection admixed with three quinolone antibiotics.
    The Annals of pharmacotherapy, 2000, Volume: 34, Issue:9

    Topics: Acetamides; Anti-Infective Agents; Ciprofloxacin; Drug Stability; Levofloxacin; Linezolid; Ofloxacin; Oxazolidinones

2000
Ciprofloxacin- and methicillin-resistant staphylococcus aureus susceptible to moxifloxacin, levofloxacin, teicoplanin, vancomycin and linezolid.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2001, Volume: 20, Issue:7

    Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Base Sequence; Ciprofloxacin; Drug Resistance, Multiple; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Molecular Sequence Data; Moxifloxacin; Ofloxacin; Oxazolidinones; Polymerase Chain Reaction; Quinolines; Sensitivity and Specificity; Staphylococcus aureus; Teicoplanin; Vancomycin

2001
In vitro bactericidal activities of linezolid in combination with vancomycin, gentamicin, ciprofloxacin, fusidic acid, and rifampin against Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:1

    Topics: Acetamides; Anti-Bacterial Agents; Ciprofloxacin; Drug Combinations; Fusidic Acid; Gentamicins; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Rifampin; Staphylococcus aureus; Vancomycin

2003
[Sensitivity of methicillin resistant staphylococci to linezolid and some other antimicrobial agents].
    Mikrobiyoloji bulteni, 2003, Volume: 37, Issue:4

    Topics: Acetamides; Anti-Infective Agents; Ciprofloxacin; Clindamycin; Drug Resistance, Bacterial; Erythromycin; Gentamicins; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin

2003
Severe bilateral optic neuritis associated with prolonged linezolid therapy.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:6

    Topics: Acetamides; Aged; Anti-Infective Agents; Antibiotics, Antitubercular; Ciprofloxacin; Female; Functional Laterality; Humans; Linezolid; Optic Neuritis; Oxazolidinones; Prosthesis-Related Infections; Rifampin

2004
Comparative efficacies of quinupristin-dalfopristin, linezolid, vancomycin, and ciprofloxacin in treatment, using the antibiotic-lock technique, of experimental catheter-related infection due to Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:10

    Topics: Acetamides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Catheters, Indwelling; Ciprofloxacin; Disease Models, Animal; Drug Therapy, Combination; Linezolid; Male; Oxazolidinones; Plankton; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin; Virginiamycin

2005
Comparative study of antimicrobial release kinetics from polymethylmethacrylate.
    Clinical orthopaedics and related research, 2006, Volume: 445

    Topics: Acetamides; Anti-Bacterial Agents; Area Under Curve; Cefazolin; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Linezolid; Ofloxacin; Oxazolidinones; Polymethyl Methacrylate; Rifampin

2006
Urinary bactericidal activity of oral antibiotics against common urinary tract pathogens in an ex vivo model.
    Chemotherapy, 2006, Volume: 52, Issue:6

    Topics: Acetamides; Administration, Oral; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; beta-Lactamases; Biomarkers; Cefadroxil; Ceftibuten; Cefuroxime; Cephalexin; Cephalosporins; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Middle Aged; Norfloxacin; Oxazolidinones; Time Factors; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections

2006
Disseminated nontuberculous mycobacterial infections in sickle cell anemia patients.
    Journal of pediatric hematology/oncology, 2006, Volume: 28, Issue:10

    Topics: Acetamides; Adolescent; Amikacin; Anemia, Sickle Cell; Anti-Bacterial Agents; Cefoxitin; Ciprofloxacin; Clarithromycin; Doxycycline; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Linezolid; Microbial Sensitivity Tests; Mycobacterium fortuitum; Mycobacterium Infections; Oxazolidinones; Treatment Outcome

2006
Successful recovery after disseminated infection due to mycobacterium abscessus in a lung transplant patient: subcutaneous nodule as first manifestation--a case report.
    Transplantation proceedings, 2007, Volume: 39, Issue:7

    Topics: Acetamides; Adolescent; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Cystic Fibrosis; Humans; Linezolid; Lung Transplantation; Male; Mycobacterium; Mycobacterium Infections; Oxazolidinones; Postoperative Complications; Sputum

2007
Ciprofloxacin-induced Q-T interval prolongation.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2008, Mar-15, Volume: 65, Issue:6

    Topics: Abscess; Acetamides; Adolescent; Anti-Infective Agents; Aztreonam; Bradycardia; Ciprofloxacin; Crohn Disease; Humans; Infusions, Intravenous; Linezolid; Long QT Syndrome; Male; Metronidazole; Oxazolidinones; Randomized Controlled Trials as Topic

2008
Disseminated Nocardia infection with subretinal abscess.
    Eye (London, England), 2010, Volume: 24, Issue:1

    Topics: Abscess; Acetamides; Adult; Anti-Infective Agents; Ciprofloxacin; Diagnosis, Differential; Female; Humans; Immunocompromised Host; Linezolid; Nocardia; Nocardia Infections; Oxazolidinones; Retinal Diseases; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination

2010
Incidence of vancomycin-resistant enterococci (VRE) infection in high-risk febrile neutropenic patients colonized with VRE.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010, Volume: 19, Issue:2

    Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Case-Control Studies; Ciprofloxacin; Daptomycin; Enterococcus; Female; Fever; Humans; Incidence; Linezolid; Male; Middle Aged; Neutropenia; Oxazolidinones; Retrospective Studies; Vancomycin; Vancomycin Resistance

2010
Prophylactic oral antibiotics reduce reinfection rates following two-stage revision total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:1

    Topics: Acetamides; Administration, Oral; Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthroplasty, Replacement, Knee; Ciprofloxacin; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Knee Prosthesis; Linezolid; Oxazolidinones; Prevalence; Prospective Studies; Prosthesis-Related Infections; Reoperation; Retrospective Studies; Staphylococcal Infections; Staphylococcus; Trimethoprim, Sulfamethoxazole Drug Combination

2011
Activity of vancomycin, ciprofloxacin, daptomycin, and linezolid against coagulase-negative staphylococci bacteremia.
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2011, Volume: 24, Issue:2

    Topics: Acetamides; Bacteremia; Catheter-Related Infections; Ciprofloxacin; Cross Infection; Daptomycin; Drug Resistance, Multiple, Bacterial; Hospital Departments; Hospitals, University; Humans; Length of Stay; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Spain; Staphylococcal Infections; Staphylococcus epidermidis; Staphylococcus haemolyticus; Staphylococcus hominis; Vancomycin

2011
Differential effects of linezolid and ciprofloxacin on toxin production by Bacillus anthracis in an in vitro pharmacodynamic system.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1

    Topics: Acetamides; Anthrax; Anti-Bacterial Agents; Bacillus anthracis; Bacterial Load; Bacterial Toxins; Ciprofloxacin; Diffusion Chambers, Culture; Infusion Pumps; Linezolid; Microbial Sensitivity Tests; Models, Biological; Oxazolidinones; Spores, Bacterial

2012
[Influence of inoculum size on MICs for methicillin-susceptible Staphylococcus aureus and methicillin-resistant Staphylococcus aureus].
    The Japanese journal of antibiotics, 2011, Volume: 64, Issue:4

    Topics: Acetamides; Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Bacteriological Techniques; Cefazolin; Ciprofloxacin; Dibekacin; Drug Resistance, Bacterial; Linezolid; Meropenem; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus aureus; Teicoplanin; Thienamycins; Vancomycin

2011
Effectiveness of ciprofloxacin or linezolid in combination with rifampicin against Enterococcus faecalis in biofilms.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:2

    Topics: Acetamides; Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Colony Count, Microbial; Enterococcus faecalis; Humans; Linezolid; Microbial Sensitivity Tests; Microbial Viability; Oxazolidinones; Rifampin

2012
Impact of spores on the comparative efficacies of five antibiotics for treatment of Bacillus anthracis in an in vitro hollow fiber pharmacodynamic model.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:3

    Topics: Acetamides; Anti-Bacterial Agents; Aza Compounds; Bacillus anthracis; Ciprofloxacin; Doxycycline; Fluoroquinolones; Linezolid; Meropenem; Microbial Sensitivity Tests; Microbial Viability; Models, Biological; Moxifloxacin; Oxazolidinones; Predictive Value of Tests; Quinolines; Spores, Bacterial; Thienamycins; Viral Load

2012
Effect of linezolid on the 50% lethal dose and 50% protective dose in treatment of infections by Gram-negative pathogens in naive and immunosuppressed mice and on the efficacy of ciprofloxacin in an acute murine model of septicemia.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:9

    Topics: Acetamides; Animals; Anti-Bacterial Agents; Ciprofloxacin; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Female; Immunocompromised Host; Klebsiella Infections; Klebsiella pneumoniae; Lethal Dose 50; Linezolid; Mice; Models, Animal; Oxazolidinones; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Survival Rate; Treatment Outcome

2012
[Microbiological monitoring in therapy of patients with iatrogenic esophageotracheal fistula].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2012, Volume: 57, Issue:3-4

    Topics: Acetamides; Anti-Bacterial Agents; Candida; Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Follow-Up Studies; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Iatrogenic Disease; Imipenem; Intubation, Intratracheal; Linezolid; Microbial Sensitivity Tests; Monitoring, Physiologic; Oxazolidinones; Polymyxin B; Pseudomonas aeruginosa; Respiratory Tract Infections; Staphylococcus aureus; Staphylococcus epidermidis; Tracheoesophageal Fistula; Vancomycin

2012
Adsorption of various antimicrobial agents to endotoxin removal polymyxin-B immobilized fiber (Toraymyxin®). Part 2: Adsorption of two drugs to Toraymyxin PMX-20R cartridges.
    Colloids and surfaces. B, Biointerfaces, 2013, Jan-01, Volume: 101

    Topics: Acetamides; Adsorption; Anti-Bacterial Agents; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Endotoxins; Humans; Kinetics; Linezolid; Oxazolidinones; Polymyxin B; Renal Dialysis; Serum

2013
Otogenic cerebellar abscess by Enterococcus avium, a very rare infectious agent.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2013, Volume: 74 Suppl 1

    Topics: Acetamides; Anti-Bacterial Agents; Brain Abscess; Cerebellar Diseases; Ciprofloxacin; Enterococcus; Female; Gram-Negative Bacterial Infections; Humans; Injections, Intravenous; Linezolid; Magnetic Resonance Imaging; Metronidazole; Middle Aged; Nervous System Diseases; Oxazolidinones; Tomography, X-Ray Computed

2013
[Nocardia pseudobrasiliensis pneumonia in a heart transplant recipient].
    Medecine et maladies infectieuses, 2013, Volume: 43, Issue:2

    Topics: Acetamides; Adult; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Heart Transplantation; Humans; Imipenem; Immunocompromised Host; Linezolid; Male; Nocardia; Nocardia Infections; Oxazolidinones; Pneumonia, Bacterial; Postoperative Complications; Tomography, X-Ray Computed; Trimethoprim, Sulfamethoxazole Drug Combination

2013
Molecular characterization and antibiotic resistance of clinical isolates of methicillin-resistant Staphylococcus aureus obtained from Southeast of Iran (Kerman).
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2014, Volume: 122, Issue:5

    Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Child; Child, Preschool; Ciprofloxacin; Clindamycin; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Erythromycin; Exotoxins; Gentamicins; Humans; Infant; Iran; Leukocidins; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Micrococcal Nuclease; Middle Aged; Oxazolidinones; Penicillin-Binding Proteins; Phenotype; Prevalence; Staphylococcal Infections; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin; Young Adult

2014
Quantification of piperacillin, tazobactam, cefepime, meropenem, ciprofloxacin and linezolid in serum using an isotope dilution UHPLC-MS/MS method with semi-automated sample preparation.
    Clinical chemistry and laboratory medicine, 2015, Volume: 53, Issue:5

    Topics: Analytic Sample Preparation Methods; Anti-Bacterial Agents; Automation; Blood Chemical Analysis; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Ciprofloxacin; Humans; Isotopes; Linezolid; Meropenem; Penicillanic Acid; Piperacillin; Tandem Mass Spectrometry; Tazobactam; Thienamycins; Time Factors

2015
Detection of drug susceptibility in rapidly growing mycobacteria by resazurin broth microdilution assay.
    Journal of microbiological methods, 2015, Volume: 111

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Linezolid; Microbial Sensitivity Tests; Nontuberculous Mycobacteria; Oxazines; Xanthenes

2015
Differences in antibiotic-induced oxidative stress responses between laboratory and clinical isolates of Streptococcus pneumoniae.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:9

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Erythromycin; Linezolid; Microbial Sensitivity Tests; Mutation; Oxidative Stress; Penicillins; Streptococcus pneumoniae; Tetracycline

2015
Japanese nationwide surveillance in 2011 of antibacterial susceptibility patterns of clinical isolates from complicated urinary tract infection cases.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2015, Volume: 21, Issue:9

    Topics: Aged; Aged, 80 and over; Amikacin; Ampicillin; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Enterococcus faecalis; Escherichia coli; Female; Fluoroquinolones; Gram-Negative Bacteria; Humans; Imipenem; Japan; Klebsiella oxytoca; Klebsiella pneumoniae; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Population Surveillance; Proteus mirabilis; Pseudomonas aeruginosa; Serratia marcescens; Urinary Tract Infections; Vancomycin

2015
Efficacy of Single and Combined Antibiotic Treatments of Anthrax in Rabbits.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:12

    Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; Anthrax; Anti-Bacterial Agents; Bacillus anthracis; Bacteremia; Ciprofloxacin; Clarithromycin; Disease Models, Animal; Doxycycline; Drug Combinations; Drug Synergism; Humans; Imipenem; Linezolid; Male; Microbial Sensitivity Tests; Rabbits; Respiratory Tract Infections; Rifampin; Spores, Bacterial; Survival Analysis; Vancomycin

2015
Antibiotic susceptibility among Staphylococcus epidermidis isolated from prosthetic joint infections, with focus on doxycycline.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2015, Volume: 123, Issue:12

    Topics: Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Clindamycin; Cross Infection; Doxycycline; Drug Resistance, Multiple, Bacterial; Fusidic Acid; Humans; Joint Prosthesis; Linezolid; Microbial Sensitivity Tests; Prosthesis-Related Infections; Rifampin; Staphylococcal Infections; Staphylococcus epidermidis

2015
Inhibitory Interaction Potential of 22 Antituberculosis Drugs on Organic Anion and Cation Transporters of the SLC22A Family.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:11

    Topics: 1-Methyl-4-phenylpyridinium; Aminosalicylic Acid; Animals; Antitubercular Agents; Ciprofloxacin; HEK293 Cells; Humans; Inhibitory Concentration 50; Ion Transport; Kinetics; Levofloxacin; Linezolid; Metformin; Octamer Transcription Factor-1; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 2; Pyrazinamide; Rifabutin; Rifampin; Zidovudine

2016
Antibiofilm Activity and Synergistic Inhibition of Staphylococcus aureus Biofilms by Bactericidal Protein P128 in Combination with Antibiotics.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:12

    Topics: Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Daptomycin; Drug Combinations; Drug Resistance, Multiple, Bacterial; Gentamicins; Linezolid; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Recombinant Fusion Proteins; Staphylococcus aureus; Vancomycin

2016
Selection of Resistance to Clarithromycin in Mycobacterium abscessus Subspecies.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:1

    Topics: Amikacin; Anti-Bacterial Agents; Cefoxitin; Ciprofloxacin; Clarithromycin; Imipenem; Linezolid; Microbial Sensitivity Tests; Minocycline; Mutation; Mycobacterium; Tigecycline

2017
Development and validation of a fast micro-extraction by packed sorbent UHPLC-PDA method for the simultaneous determination of linezolid and ciprofloxacin in human plasma from patients with hospital-acquired pneumonia.
    Talanta, 2017, Mar-01, Volume: 164

    Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Cross Infection; Electrical Equipment and Supplies; Humans; Limit of Detection; Linezolid; Pneumonia; Solid Phase Microextraction; Time Factors

2017
Development of a dried blood spot HPLC-PDA method for the analysis of linezolid and ciprofloxacin in hospital-acquired pneumonia patients.
    Drug testing and analysis, 2017, Volume: 9, Issue:10

    Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Cross Infection; Dried Blood Spot Testing; Drug Monitoring; Humans; Limit of Detection; Linezolid; Pneumonia

2017
Human Bile Reduces Antimicrobial Activity of Selected Antibiotics against Enterococcus faecalis and Escherichia coli
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:8

    Topics: Adult; Aged; Anti-Bacterial Agents; Bile; Biliary Tract; Ciprofloxacin; Enterococcus faecalis; Escherichia coli; Female; Gallbladder Diseases; Humans; Linezolid; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Minocycline; Thienamycins; Tigecycline

2017
A complicated prosthetic valve endocarditis due to methicillin resistant Staphylococci treated with linezolid and ciprofloxacin: a case report.
    BMC research notes, 2017, Nov-09, Volume: 10, Issue:1

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Therapy, Combination; Endocarditis, Bacterial; Heart Valve Prosthesis; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Prosthesis-Related Infections

2017
In vitro activity of tedizolid against the Mycobacterium abscessus complex.
    Diagnostic microbiology and infectious disease, 2018, Volume: 90, Issue:3

    Topics: Amikacin; Anti-Bacterial Agents; Ciprofloxacin; Clarithromycin; Drug Combinations; Drug Resistance, Multiple, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Minocycline; Mycobacterium abscessus; Mycobacterium Infections, Nontuberculous; Oxazolidinones; Tetrazoles; Tigecycline

2018
Treating Anthrax-Induced Meningitis in Rabbits.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:7

    Topics: Animals; Anthrax; Anti-Bacterial Agents; Antitoxins; Bacillus anthracis; Central Nervous System; Ciprofloxacin; Clindamycin; Dexamethasone; Disease Models, Animal; Drug Combinations; Imipenem; Levofloxacin; Linezolid; Meningitis, Bacterial; Meropenem; Rabbits; Treatment Failure

2018
Psoas and neck abscess by Nocardia farcinica.
    Cirugia espanola, 2019, Volume: 97, Issue:2

    Topics: Aged; Aminoglycosides; Ciprofloxacin; Coinfection; Drainage; Humans; Linezolid; Male; Neck; Nocardia; Nocardia Infections; Obesity; Pseudomonas aeruginosa; Pseudomonas Infections; Psoas Abscess

2019
Detection of oxazolidinone and phenicol resistant enterococcal isolates from duck feces and carcasses.
    International journal of food microbiology, 2019, Mar-16, Volume: 293

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; Chloramphenicol; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Ducks; Enterococcus faecalis; Enterococcus faecium; Erythromycin; Feces; Genes, Bacterial; Linezolid; Microbial Sensitivity Tests; Multilocus Sequence Typing; Oxazolidinones; Republic of Korea; Ribosomal Protein L3; RNA, Ribosomal, 23S; Tetracycline; Thiamphenicol

2019
Evaluation and validation of Biolog OmniLog
    Letters in applied microbiology, 2021, Volume: 72, Issue:5

    Topics: Anti-Bacterial Agents; Automation, Laboratory; Ciprofloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Linezolid; Microbial Sensitivity Tests; Piperacillin

2021
Simultaneous quantification of plasma levels of 12 antimicrobial agents including carbapenem, anti-methicillin-resistant Staphylococcus aureus agent, quinolone and azole used in intensive care unit using UHPLC-MS/MS method.
    Clinical biochemistry, 2021, Volume: 90

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Azoles; Carbapenems; Chromatography, High Pressure Liquid; Ciprofloxacin; Daptomycin; Doripenem; Drug Monitoring; Female; Fluconazole; Fluoroquinolones; Humans; Intensive Care Units; Levofloxacin; Linezolid; Male; Meropenem; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazines; Oxazolidinones; Quinolones; Tandem Mass Spectrometry; Tetrazoles; Voriconazole

2021
Occurrence of multidrug-resistant Enterococcus faecium isolated from environmental samples.
    Letters in applied microbiology, 2021, Volume: 73, Issue:2

    Topics: Aminoglycosides; Anti-Bacterial Agents; Ciprofloxacin; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Enterococcus faecium; Environmental Microbiology; Fluoroquinolones; Gram-Positive Bacterial Infections; Linezolid; Microbial Sensitivity Tests; Polymerase Chain Reaction; Prevalence; Vancomycin; Virulence; Virulence Factors

2021
CE-DAD-MS/MS in the simultaneous determination and identification of selected antibiotic drugs and their metabolites in human urine samples.
    Electrophoresis, 2022, Volume: 43, Issue:9-10

    Topics: Amoxicillin; Anti-Bacterial Agents; Cefotaxime; Ciprofloxacin; Clindamycin; Electrophoresis, Capillary; Humans; Linezolid; Metronidazole; Tandem Mass Spectrometry

2022
Development and validation of a resazurin assay for in vitro susceptibility testing of Actinomadura madurae: a common causative agent of actinomycetoma.
    The Journal of antimicrobial chemotherapy, 2022, 12-23, Volume: 78, Issue:1

    Topics: Amikacin; Amoxicillin; Anti-Bacterial Agents; Ceftriaxone; Ciprofloxacin; Doxycycline; Humans; Ifosfamide; Imipenem; Linezolid; Microbial Sensitivity Tests; Mycetoma; Rifampin; Trimethoprim, Sulfamethoxazole Drug Combination

2022
UHPLC-MS/MS method for simultaneous quantification of doripenem, meropenem, ciprofloxacin, levofloxacin, pazufloxacin, linezolid, and tedizolid in filtrate during continuous renal replacement therapy.
    Journal of clinical laboratory analysis, 2023, Volume: 37, Issue:1

    Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Continuous Renal Replacement Therapy; Doripenem; Humans; Levofloxacin; Linezolid; Meropenem; Tandem Mass Spectrometry

2023
[The Importance of Gram-stained Smears in the Diagnosis of Nocardia Infections].
    Mikrobiyoloji bulteni, 2023, Volume: 57, Issue:1

    Topics: Amikacin; Anti-Bacterial Agents; Cefepime; Cefotaxime; Ceftriaxone; Ciprofloxacin; Clarithromycin; Humans; Imipenem; Linezolid; Nocardia; Nocardia Infections; RNA, Ribosomal, 16S; Trimethoprim, Sulfamethoxazole Drug Combination

2023
[Evaluation of Antimicrobial Susceptibilities of Rapidly Growing Mycobacteria].
    Mikrobiyoloji bulteni, 2023, Volume: 57, Issue:2

    Topics: Amikacin; Anti-Bacterial Agents; Cefoxitin; Ciprofloxacin; Clarithromycin; Doxycycline; Humans; Imipenem; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Tobramycin

2023
Detection of Genes Encoding Microbial Surface Component Recognizing Adhesive Matrix Molecules in Methicillin-Resistant
    Genes, 2023, 03-24, Volume: 14, Issue:4

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Cefoxitin; Ceftaroline; Chloramphenicol; Ciprofloxacin; Clindamycin; Erythromycin; Gentamicins; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Pyoderma; Rifampin; Staphylococcus aureus

2023