ciprofloxacin and itraconazole

ciprofloxacin has been researched along with itraconazole in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (8.33)18.2507
2000's9 (37.50)29.6817
2010's13 (54.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Cho, SJ; Park, KD1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Ahmad, A; Khan, AU; Rauf, A; Rehan, M; Subbarao, N; Varshney, H1
Al-Dhfyan, A; Al-Dosari, MS; Al-Omar, MA; Bhat, MA; Khan, AA; Khan, S; Parvez, MK1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chandrasekaran, B; Cherukupalli, S; Hampannavar, GA; Karpoormath, R; Palakollu, VN; Thapliyal, N1
Gao, F; Huang, G; Xiao, J1
de'Clari, F1
Brunet, J; Cancelas, JA; López-López, JJ; Maroto, P; Mendoza, L; Montesinos, J; Ojeda, B; Rodríguez, M; Salazar, R; Solá, C; Tabernero, JM; Valentí, V; Verger, G1
Borlenghi, E; Capucci, MA; Carosi, GP; Cattaneo, C; Franco, F; Grazioli, L; Pan, A; Quaresmini, G; Rossi, G1
Abou-Auda, HS; Al-Humayyd, MS; Mustafa, AA1
Arechavala, AI; Bianchi, MH; González, G; Maiolo, E; Negroni, R; Orduna, T; Santiso, G1
de Mol, P; Meis, JF1
Mahatthanatrakul, W; Ridtitid, W; Samaeng, M; Sriwiriyajan, S; Wongnawa, M1
Daali, Y; Desmeules, JA; Marsousi, N; Rudaz, S1
Dong, B; Hadinoto, K; Ming Lim, L; Yu, H1

Reviews

3 review(s) available for ciprofloxacin and itraconazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
An insight on synthetic and medicinal aspects of pyrazolo[1,5-a]pyrimidine scaffold.
    European journal of medicinal chemistry, 2017, Jan-27, Volume: 126

    Topics: Animals; Chemistry Techniques, Synthetic; Humans; Pyrazoles; Pyrimidines

2017
Current scenario of tetrazole hybrids for antibacterial activity.
    European journal of medicinal chemistry, 2019, Dec-15, Volume: 184

    Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles

2019

Trials

1 trial(s) available for ciprofloxacin and itraconazole

ArticleYear
Pharmacokinetic interactions between ciprofloxacin and itraconazole in healthy male volunteers.
    Biopharmaceutics & drug disposition, 2011, Volume: 32, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Area Under Curve; Ciprofloxacin; Cross-Over Studies; Drug Interactions; Half-Life; Humans; Itraconazole; Male; Young Adult

2011

Other Studies

20 other study(ies) available for ciprofloxacin and itraconazole

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Synthesis and antimicrobial activities of 3-O-alkyl analogues of (+)-catechin: improvement of stability and proposed action mechanism.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Anti-Infective Agents; Bacteria; Camellia sinensis; Catechin; Drug Design; Drug Stability; Fungi; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Molecular Structure; Tea

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Designing and synthesis of novel antimicrobial heterocyclic analogs of fatty acids.
    European journal of medicinal chemistry, 2013, Volume: 70

    Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Candida; Cyclization; Dose-Response Relationship, Drug; Drug Design; Fatty Acids; Heterocyclic Compounds; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Software; Structure-Activity Relationship

2013
Synthesis and anti-Candidal activity of N-(4-aryl/cyclohexyl)-2-(pyridine-4-yl carbonyl) hydrazinecarbothioamide.
    Bioorganic & medicinal chemistry letters, 2014, Mar-01, Volume: 24, Issue:5

    Topics: Antifungal Agents; Candida albicans; Cell Line, Tumor; Cell Survival; Drug Resistance, Fungal; Hep G2 Cells; Humans; Hydrazines; Microbial Sensitivity Tests; Molecular Conformation; Pyridines; Thioamides

2014
Ciprofloxacin was the culprit--not itraconazole.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Bronchodilator Agents; Central Nervous System; Ciprofloxacin; Clarithromycin; Drug Interactions; Drug Therapy, Combination; Humans; Itraconazole; Theophylline; Time Factors

1997
Infectious complications in 126 patients treated with high-dose chemotherapy and autologous peripheral blood stem cell transplantation.
    Bone marrow transplantation, 1999, Volume: 23, Issue:1

    Topics: Acyclovir; Adolescent; Adult; Anti-Infective Agents; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Ciprofloxacin; Combined Modality Therapy; Communicable Diseases; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Itraconazole; Male; Middle Aged; Neoplasms; Prospective Studies; Staphylococcal Infections; Staphylococcus epidermidis; Transplantation, Autologous; Treatment Outcome

1999
Usefulness of the MSG/IFICG/EORTC diagnostic criteria of invasive pulmonary aspergillosis in the clinical management of patients with acute leukaemia developing pulmonary infiltrates.
    Annals of hematology, 2007, Volume: 86, Issue:3

    Topics: Acute Disease; Adult; Aged; Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Ciprofloxacin; Female; Humans; Itraconazole; Leukemia; Male; Middle Aged; Models, Theoretical; Ofloxacin; Practice Guidelines as Topic; Reproducibility of Results; Treatment Outcome

2007
Pharmacokinetic interaction of ketoconazole and itraconazole with ciprofloxacin.
    Biopharmaceutics & drug disposition, 2008, Volume: 29, Issue:1

    Topics: Animals; Anti-Infective Agents; Antifungal Agents; Area Under Curve; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Interactions; Half-Life; Itraconazole; Ketoconazole; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Time Factors

2008
[Clinical cases in Medical Mycology. Case No. 29].
    Revista iberoamericana de micologia, 2007, Dec-31, Volume: 24, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Arthritis, Infectious; Bacteremia; Ciprofloxacin; Combined Modality Therapy; Debridement; Drainage; Drug Therapy, Combination; Glomerulonephritis; Humans; Immunocompromised Host; Itraconazole; Lymphangitis; Male; Mycetoma; Psoas Abscess; Scedosporium; Staphylococcal Infections; Vancomycin

2007
Disseminated Rhizopus microsporus infection in a patient on oral corticosteroid treatment: a case report.
    The Netherlands journal of medicine, 2009, Volume: 67, Issue:1

    Topics: Adrenal Cortex Hormones; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antifungal Agents; Ciprofloxacin; Fatal Outcome; Humans; Itraconazole; Male; Mucormycosis; Prednisolone; Pyrimidines; Rhizopus; Triazoles; Voriconazole

2009
Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software.
    Biopharmaceutics & drug disposition, 2018, Volume: 39, Issue:1

    Topics: Ciprofloxacin; Clarithromycin; Computer Simulation; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inducers; Drug Interactions; Fluconazole; Humans; Itraconazole; Ketoconazole; Models, Biological; Paroxetine; Quinidine; Rifampin; Software

2018
Proof-of-concept preparation and characterization of dual-drug amorphous nanoparticle complex as fixed-dose combination of poorly soluble drugs.
    Drug development and industrial pharmacy, 2019, Volume: 45, Issue:1

    Topics: Anti-Bacterial Agents; Antifungal Agents; Ciprofloxacin; Drug Carriers; Drug Combinations; Itraconazole; Nanoparticles; Proof of Concept Study; Solubility

2019