ciprofloxacin has been researched along with isoniazid in 192 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (2.60) | 18.7374 |
| 1990's | 12 (6.25) | 18.2507 |
| 2000's | 26 (13.54) | 29.6817 |
| 2010's | 132 (68.75) | 24.3611 |
| 2020's | 17 (8.85) | 2.80 |
| Authors | Studies |
|---|---|
| Sriram, D; Thirumurugan, R; Yogeeswari, P | 1 |
| Christiansen, HC; Copp, BR; G Franzblau, S; Lindsay, BS | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S | 1 |
| Imramovský, A; Jampílek, J; Kaustová, J; Kocevar, M; Polanc, S; Recková, Z; Vinsová, J | 1 |
| Adamec, J; Beckert, R; Buchta, V; Kaustová, J; Klimesová, V; Möllmann, U; Waisser, K; Weiss, D | 1 |
| China, A; Dinakaran, M; Nagaraja, V; Senthilkumar, P; Sriram, D; Yogeeswari, P | 1 |
| Gadaginamath, GS; Joshi, SD; Vagdevi, HM; Vaidya, VP | 1 |
| Bitting, C; Gruppo, V; Johnson, CM; Lenaerts, AJ; Marietta, KS; Orme, IM; Woolhiser, L | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Kumar, RR; Perumal, S; Senthilkumar, P; Sriram, D; Yogeeswari, P | 1 |
| Connell, TG; Curtis, N; Ritz, N; Robins-Browne, R; Sievers, A; Tebruegge, M | 1 |
| Banerjee, D; Dhakla, P; Manjashetty, TH; Senthilkumar, P; Sriram, D; Yogeeswari, P | 1 |
| Amirthaganesan, S; Aridoss, G; Jeong, YT; Kim, JT; Kim, MS | 1 |
| Gaillard, JL; Jackson, M; McDonnell, G; Niederweis, M; Skovierová, H; Svetlíková, Z | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Chandrashekar, SM; Mallikarjuna, BP; Rajendraprasad, Y; Sastry, BS; Sathisha, K; Suresh Kumar, GV | 1 |
| Banerjee, D; Kumar, RS; Perumal, S; Rajesh, SM; Sriram, D; Yogeeswari, P | 1 |
| Kumar, RS; Perumal, S; Shetty, KA; Sriram, D; Yogeeswari, P | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Adhikari, AV; Ajay Kumar, R; Eswaran, S | 1 |
| Hamilton, C; Houghton, PJ; Hussein, AA; Kikuchi, H; Lall, N; Mativandlela, SP; Muthivhi, T; Oshima, Y; van der Walt, ML | 1 |
| Chandrashekar, SM; Kistayya, C; Mallikarjuna, BP; Rajendraprasad, Y; Suresh Kumar, GV | 1 |
| Ding, Y; Ferreira, D; Franzblau, S; Hamann, MT; Kelly, M; Li, XC; Na, M; Schinazi, RF; Stone, R; Tekwani, BL; Wang, B | 1 |
| Adhikari, AV; Chowdhury, IH; Eswaran, S; Pal, NK; Thomas, KD | 1 |
| Chandrashekar, SM; Mallikarjuna, BP; Rajendra Prasad, Y; Suresh Kumar, GV | 1 |
| Kumar, P; Narasimhan, B; Sriram, D; Yogeeswari, P | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Balamurugan, K; Perumal, S; Prasanna, P; Sriram, D; Yogeeswari, P | 1 |
| Balamurugan, K; Maheswari, SU; Perumal, S; Sriram, D; Yogeeswari, P | 1 |
| Bauer, R; Blunder, M; Bucar, F; Hüfner, A; Kollroser, M; Thomaschitz, C; Wube, AA | 1 |
| Chai, Y; Feng, LS; Guan, Y; Guo, HY; Liu, ML; Lv, K; Wang, B; Xiao, CL; Zhang, S; Zhang, YB | 1 |
| Chiba, T; Hasegawa, T; Horita, Y; Kremer, L; Kuroishi, R; Lee, Y; Ogawa, K; Onozaki, K; Sato, Y; Takii, T | 1 |
| Baltas, M; Bedos-Belval, F; Constant, P; Daffé, M; De, P; Duran, H; Koumba Yoya, G; Saffon, N | 1 |
| Bauer, R; Blunder, M; Bucar, F; Hochfellner, C; Hüfner, A; Wube, AA | 1 |
| Adhikari, AV; Chowdhury, IH; Pal, NK; Sumesh, E; Thomas, KD | 1 |
| Kumar, RS; Libertsen, LA; Perumal, S; Rajesh, SM; Sriram, D; Yogeeswari, P | 1 |
| Kalivendi, SV; Raju, BC; Rao, RN; Shaik, TB; Sriram, D; Suman, P; Yogeeswari, P | 1 |
| Menéndez, JC; Perumal, S; Ranjith Kumar, R; Sriram, D; Yogeeswari, P | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Perumal, S; Raja, VP; Sriram, D; Yogeeswari, P | 1 |
| Gunasekaran, P; Perumal, S; Sriram, D; Yogeeswari, P | 1 |
| Alvala, M; Jeankumar, VU; Methuku, S; Senthilkumar, P; Sriram, D; Vyas, DR; Yogeeswari, P | 1 |
| Bosze, S; Horváti, K; Kočevar, M; Polanc, S; Stolaříková, J; Vavříková, E; Vávrová, K; Vinšová, J | 1 |
| Chitra, S; Manisankar, P; Muthusubramanian, S; Paul, N; Sriram, D; Yogeeswari, P | 2 |
| Adhikari, AV; Bhattacharya, B; Chowdhury, IH; Mahmood, R; Sandeep, T; Sumesh, E; Thomas, KD | 1 |
| Adhikari, AV; Chowdhury, IH; Mahmood, R; Pal, NK; Row, G; Sumesh, E; Telkar, S; Thomas, KD | 1 |
| Aiello, C; Anzaldi, M; Balbi, A; Castagnola, P; Gangemi, R; Macciò, C; Mazzei, M; Miele, M; Rosano, C; Viale, M | 1 |
| Bernadou, J; Bernardes-Génisson, V; Constant, P; Deraeve, C; Dorobantu, IM; Le Quéméner, F; Pratviel, G; Quémard, A; Rebbah, F | 1 |
| Akhaja, TN; Raval, JP | 1 |
| Ahsan, MJ; Gaur, R; Khalilullah, H; Nomani, MS; Samy, JG; Saraswat, P; Singh, A | 1 |
| Murugavel, M; Muthusubramanian, S; Paul, N; Sriram, D | 1 |
| Haridas, KR; Karuvalam, RP; Kumari, NS; Nayak, SK; Rajeesh, P; Rishikesan, R; Row, TN | 1 |
| Constant, P; Daffé, M; Massimba Dibama, H; Mourer, M; Regnouf-de-Vains, JB | 1 |
| Bucar, F; Gröblacher, B; Kunert, O | 1 |
| Chikhalia, KH; Kumari, P; Patel, PK; Patel, RV; Rajani, DP | 1 |
| Almansour, AI; Arumugam, N; Sriram, D; Suresh Kumar, R | 1 |
| Barad, HA; Gupta, VK; Kant, R; Pansuriya, BR; Parmar, NJ | 1 |
| Patel, MP; Patel, RG; Shah, NM | 1 |
| Bonifácio, VD; Gawande, MB; Mhaske, GR; Shelke, SN | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Gutte, SD; Rane, RA; Sahu, NU | 1 |
| Parmar, BD; Parmar, NJ; Patel, RA; Talpada, NP | 1 |
| Kathrotiya, HG; Patel, MP | 1 |
| Bao, L; Cai, L; Chen, JL; Huang, P; Liu, HW; Liu, MM; Qi, QY; Wang, QX; Yang, JL; Yang, XL; Zhang, LX | 1 |
| Jardosh, HH; Patel, MP | 1 |
| Haridas, KR; Kumari, NS; Rajeesh, P; Ranjith, PK; Rishikesan, R; Row, TN; Susanta, NK | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Cížek, A; Imramovský, A; Jampílek, J; Masaříková, M; Pauk, K; Pokorná, M; Vinšová, J; Zadražilová, I | 1 |
| Bangalore, P; Borhade, SD; Khandare, PK; Rane, RA | 1 |
| Cai, G; Cho, S; Franzblau, SG; Jaki, BU; Lee, IA; McAlpine, JB; Napolitano, JG; Pauli, GF; Suh, JW; Wang, Y; Yang, SH | 1 |
| Haridas, KR; Kumari, SN; Pakkath, R; Ranjith, PK | 1 |
| Doležal, M; Kubíček, V; Kučera, R; Kuneš, J; Mandíková, J; Paterová, P; Servusová, B; Zitko, J | 1 |
| Nallangi, R; Samala, G; Sridevi, JP; Sriram, D; Yogeeswari, P | 1 |
| Balkan, A; Dharmarajan, S; Ozadali, K; Tan, OU; Yogeeswari, P | 1 |
| Kalaria, PN; Raval, DK; Satasia, SP | 1 |
| Achar, V; Arora, U; Awasthy, D; Bharath, S; Bheemarao, U; Chinnapattu, M; Coulson, M; de Sousa, SM; Ganguly, S; Gaonkar, S; Ghosh, A; Hameed P, S; Hoffner, S; Humnabadkar, V; Kaur, P; Kumar K N, M; Kumar, CN; Madhavapeddi, P; Manjrekar, P; Menasinakai, S; Mukherjee, K; Nandishaiah, R; Narayan, C; Panduga, V; Patil, V; Puttur, J; Raichurkar, A; Ramya, VK; Reddy, J; Rudrapatana, S; Sambandamurthy, VK; Shanbhag, G; Sharma, S; Sharma, U; Shinde, V; Solapure, S; Waterson, D; Werngren, J | 1 |
| Desai, NC; Kotadiya, GM; Trivedi, AR | 1 |
| Bangalore, PK; Karpoormath, R; Naphade, SS; Palkar, MB; Rane, RA; Shaikh, MS | 1 |
| Desai, NC; Desai, P; Kotadiya, GM; Shihory, NR | 1 |
| Karad, SC; Purohit, VB; Raval, DK | 1 |
| Basireddy, VS; Dharmarajan, S; Guttala, RS; Jagarlamudi, PS; Mukkara, LD; Pagadala, LR; Perumal, Y; Ravirala, N; Singh, A; Singireddi, S; Thummaluru, VR; Ummanni, R; Upadhyayula, SM | 1 |
| Hameed P, S; Kaur, P; Madhavapeddi, P; Menasinakai, S; Nandishaiah, R; Panduga, V; Raichurkar, A; Reddy, J; Sambandamurthy, VK; Sharma, S; Sriram, D | 1 |
| Guo, H; Huang, J; Liu, H; Liu, M; Lu, Y; Wang, B; Wang, J; Wang, M | 1 |
| Alam, MZ; Bruhn, DF; Feng, L; Hurdle, JG; Lee, RB; Lee, RE; Maddox, MM; Narula, G; Sandhaus, S; Simmons, CJ; Sun, D; Tse-Dinh, YC; Tsutsumi, LS; Wu, X | 1 |
| Cho, S; Franzblau, SG; Miller, MJ; Miller, PA; Tiwari, R | 1 |
| Bharate, SS; Vishwakarma, RA | 1 |
| Dayakar, C; Rajkumar, K; Raju, BC; Rao, JV; Sriram, D; Suman, P; Yashwanth, B; Yogeeswari, P | 1 |
| Augustynowicz-Kopeć, E; Bielenica, A; Boi, S; Giliberti, G; Madeddu, S; Napiórkowska, A; Sanna, G; Stefańska, J; Stępień, K; Struga, M; Wrzosek, M | 1 |
| Chinnapattu, M; Hameed P, S; Kumar, CN; Madhavapeddi, P; Manjrekar, P; Nandishaiah, R; Patil, V; Puttur, J; Raichurkar, A; Rudrapatana, S; Sambandamurthy, VK; Shanbhag, G; Sharma, S; Shinde, V; Solapure, S; Sriram, D | 1 |
| Baranyai, Z; Bősze, S; Dávid, S; Horváti, K; Krátký, M; Senoner, Z; Stolaříková, J; Szabó, N; Vinšová, J | 1 |
| Kamal, A; Ravikumar, A; Reddy, BV; Sravanthi, G; Sridevi, B; Sridevi, JP; Sriram, D; Venkateswarlu, A; Yogeeswari, P | 1 |
| Constant, P; Daffé, M; Massimba-Dibama, H; Mourer, M; Regnouf-de-Vains, JB | 1 |
| Askri, M; Boudriga, S; Golz, C; Knorr, M; Mhiri, C; Nana, F; Sriram, D; Strohmann, C; Yogeeswari, P | 1 |
| Peraman, R; Reddy, YP; Varma, RV | 1 |
| Guo, H; Li, L; Liu, M; Lu, Y; Shen, W; Wang, B; Wang, M; Zhang, R; Zhang, T | 1 |
| Huang, J; Li, L; Liu, H; Liu, M; Lu, Y; Wang, B; Wang, C; Wang, M; Zhang, R | 1 |
| Dalimba, U; Nayak, N; Ramprasad, J | 2 |
| Karad, SC; Purohit, VB; Raval, DK; Thakkar, VR; Thakor, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Feng, L; Huang, J; Li, X; Liu, M; Lu, Y; Wang, B; Wang, M; Wu, Z; Yang, Y; Zhang, J | 1 |
| Chakraborti, AK; Dhameliya, TM; Jadhavar, PS; Pancholia, S; Shah, P; Sridevi, JP; Sriram, D; Yogeshwari, P | 1 |
| Chakraborti, AK; Dhameliya, TM; Jadhavar, PS; Kumar, D; Sridevi, JP; Sriram, D; Vaja, MD; Yogeeswari, P | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Chakraborti, AK; Kumar, A; Sriram, D; Tanwar, B; Yogeeswari, P | 1 |
| Balaji, NV; Hari Babu, B; Murali Krishna Kumar, M; Purna Nagasree, K; Subbaraju, GV | 1 |
| Sankar, C; Umamatheswari, S | 1 |
| Adhikari, C; Krishna, VS; Reshma, RS; Sharada, DS; Sriram, D; Vidyacharan, S | 1 |
| Abdel-Aziz, MM; Abdelrahman, MA; Elaasser, MM; Gomaa, MS; Salama, I; Soliman, DH | 1 |
| Bernardino, AMR; Boechat, N; Dos Santos, MS; Faria, JV; Miguita, AGC; Vegi, PF | 1 |
| Coffey, A; Endersen, L; Fontinha, D; Jampilek, J; Machado, M; Pavić, K; Perković, I; Pospíšilová, Š; Prudêncio, M; Rimac, H; Zorc, B | 1 |
| Anjum, MN; Arfan, M; Ayaz, M; Batool Kazmi, ST; Farooq, S; Haq, IU; Iftikhar, F; Rashid, U; Ullah, A | 1 |
| Cheng, XW; Fan, YL; Feng, LS; Wu, JB; Zhang, FZ | 1 |
| Bimal, D; Bohra, K; Jain, R; Maity, J; Ponnan, P; Prasad, AK; Singh, B; Srivastava, S; Thirumal, M; Varma-Basil, M | 1 |
| Fan, YL; Feng, LS; Gao, T; Huang, ZP; Jin, XH; Yu, HF; Zeng, ZG | 1 |
| Banerjee, A; Chakraborti, AK; Dhameliya, TM; Pancholia, S; Panda, D; Sriram, D; Tiwari, R | 1 |
| Bhushan Tripathi, S; Chanda, D; Chaturvedi, AK; Khwaja, S; Kumar, BS; Negi, AS; Roy, S; Sachan, NK; Saikia, D; Shanker, K; Sharma, A; Thakur, JP; Verma, AK | 1 |
| Ashok, D; Goud, GL; Manga, V; Ramesh, S; Reddy, VP; Saikrishna, B; Sriram, D; Yogeeswari, P | 1 |
| Doležal, M; Jand'ourek, O; Kuneš, J; Navrátilová, L; Paterová, P; Vinšová, J; Zitko, J | 1 |
| Abdel Gawad, NM; Abdel-Aziz, MM; Abo-Ashour, MF; Abou-Seri, SM; Bhakta, S; Elaasser, MM; Eldehna, WM; George, RF; Gupta, A | 1 |
| Eswaran, S; Narayanan, S; Shivarudraiah, P; Shruthi, TG; Subramanian, S | 1 |
| Bai, L; Deng, J; Feng, L; Lv, Z; Wang, Y; Xu, Z; Zhang, F; Zhao, S | 1 |
| Bai, L; Deng, JL; Gao, F; Lv, ZS; Wang, Y; Xu, Z; Zhang, F; Zhao, SJ | 1 |
| AnkiReddy, S; Bharathi Reddy, K; Rao Sagurthi, S; Sabitha, G; Shiva Raju, K; Siva Krishna, V; Sriram, D | 1 |
| Kantevari, S; Krishna, VS; Marvadi, SK; Sriram, D | 2 |
| Dastgir, F; Haq, IU; Mahmood, T; Rashid, U; Tahir, S; Waseem, A | 1 |
| Dalimba, U; Madan Kumar, S; Reddyrajula, R | 1 |
| Akhter, M; Alam, MM; Ali, S; Deora, GS; Krishna, VS; Sharma, K; Sriram, D; Tanwar, O; Zaman, MS | 1 |
| Bera, S; Mondal, D | 1 |
| Esaulkova, YL; Kantevari, S; Krishna, VS; Marvadi, SK; Muryleva, AA; Sinegubova, EO; Sriram, D; Tentler, DG; Volobueva, AS; Zarubaev, VV | 1 |
| Caljon, G; Cappoen, D; Claes, P; Cools, F; Cos, P; De Kimpe, N; de Macedo, MB; Delputte, P; Holvoet, F; Maes, L; Mangelinckx, S; Matheeussen, A; Meiresonne, T; Neyrolles, O; Piller, T; Semina, E; Torfs, E; Van Calster, K | 1 |
| Augustynowicz-Kopeć, E; Bielenica, A; Chrzanowska, A; Dobrowolski, M; Głogowska, A; Roszkowski, P; Stępień, K; Struga, M; Szulczyk, D | 1 |
| Bangalore, PK; Bollikanda, RK; Choudante, PC; Kantevari, S; Misra, S; Sridhar, B; Sriram, D; Vagolu, SK; Veeragoni, DK | 1 |
| Krishna, VS; Sirim, MM; Sriram, D; Unsal Tan, O | 1 |
| Augustynowicz-Kopeć, E; Bojanowski, K; Foks, H; Gobis, K; Głogowska, A; Korona-Głowniak, I; Krause, M; Siluk, D; Ziembicka, D | 1 |
| Dixit, PP; Haval, KP; Haval, NB; Kasare, SL; Khedkar, VM; Patil, PS; Rekha, EM; Sriram, D | 1 |
| Behera, JN; Konduri, S; Krishna, VS; Prashanth, J; Rao, KP; Siegel, D; Sriram, D | 1 |
| Cordeiro, R; Kachroo, M | 1 |
| Daraji, DG; Jayanthi, S; Patel, HD; Pithawala, EA; Rajani, DP; Rajani, SD | 1 |
| Alexandrova, LA; Avdanina, DA; Boykova, YV; Efimenko, TA; Efremenkova, OV; Glukhova, AA; Jasko, MV; Karpenko, IL; Kochetkov, SN; Kolonitskaya, DP; Kost, NV; Negrya, SD; Nuraeva, GK; Shevchenko, OV; Solodinin, AP; Solyev, PN; Volkov, IA; Zhgun, AA | 1 |
| Trotsko, N | 1 |
| Bayannavar, PK; Hoolageri, SR; Joshi, SD; Kamble, RR; Kodasi, B; Kumbar, VM; Nesaragi, AR; Shaikh, SKJ | 1 |
| Ahmad, I; Alshahrani, MY; Jain, R; Pradeep Kumar, CB; Prashanth, MK; Raghu, MS; Yogesh Kumar, K | 1 |
| Agrahari, AK; Rajkhowa, S; Sharma, A; Tiwari, VK | 1 |
| Constant, P; Daffé, M; Guillet, V; Le, NH; Marrakchi, H; Maveyraud, L; Mourey, L; Nahoum, V; Tranier, S; Verhaeghe, P | 1 |
| Hjelm, U; Hoffner, SE; Kaustová, J; Kubín, M | 1 |
| Chadwick, M; Gaya, H; Nicholson, G | 1 |
| Berlin, OG; Bruckner, DA; Young, LS | 1 |
| Casal, M; González, J; Gutierrez, J; Ruiz, P | 1 |
| Collins, CH; Uttley, AH | 1 |
| Baird, B; Fauci, AS; Gill, V; Grimes, G; Lane, HC; Masur, H; Tuazon, C | 1 |
| Nelson, SD; Nolan, CM; Sandblom, RE; Slattery, JT; Thummel, KE | 1 |
| Gillespie, SH; Kennedy, N | 1 |
| Ahn, CH; Brown, BA; Dunbar, D; Dunlap, R; Murphy, DT; Onyi, G; Wallace, RJ | 1 |
| Fox, R; Gillespie, SH; Kennedy, N; Kisyombe, GM; Ngowi, FI; Ramsay, AR; Saruni, AO; Uiso, LO | 1 |
| Berger, L; Curram, J; Fox, R; Gillespie, SH; Gutmann, J; Kennedy, N; Kisyombe, GM; Ngowi, FI; Ramsay, AR; Sam, N; Saruni, AO; Tillotson, G; Uiso, LO; Yates, M | 1 |
| Coker, RJ; Fisher, M; Tomlinson, DR | 1 |
| Benator, DA; Gordin, FM; Kan, V | 1 |
| Fuursted, K | 1 |
| Botha, FJ; Donald, PR; Mitchison, DA; Parkin, DP; Schall, R; Sirgel, FA; Van de Wal, BW | 1 |
| Padeĭskaia, EN | 1 |
| Drobniewski, FA; Eltringham, IJ; Wilson, SM | 1 |
| Bajaksouzian, S; Jacobs, MR; Joloba, ML | 1 |
| Charalambous, BM; Gillespie, SH; Gosling, RD | 1 |
| Charalambous, BM; Gillespie, SH | 1 |
| Bose, M; Dam, T; Isa, M | 1 |
| Bhusal, Y; Shiohira, CM; Yamane, N | 1 |
| Chimara, E; da Silva Telles, MA; Ferrazoli, L; Riley, LW | 1 |
| Drobniewski, FA; Krüüner, A; Yates, MD | 1 |
| Edwards, CM; Fitzpatrick, RW | 1 |
| Campbell, PJ; Cowan, LS; Dalton, TL; Hooks, DP; Metchock, B; Morlock, GP; Plikaytis, BB; Posey, JE; Sikes, RD; Starks, AM | 1 |
| Ambrose, PG; Bhavnani, SM; Caws, M; Chau, TT; Dung, NT; Farrar, J; Hammel, JP; Hien, TT; Kulawy, R; Mai, PP; Reynolds, DK; Thwaites, GE; Török, ME; Van Wart, SA | 1 |
| Cremades, R; Galiana, A; García-Pachón, E; López, P; Rodríguez, JC; Royo, G; Ruiz-García, M | 1 |
| Abbasi, S; Ikram, A; Khalid, MM; Manzar, MA; Sattar, A; Satti, L | 1 |
| Chitnis, DS; Hemvani, N; Patidar, V | 2 |
| Balabanova, Y; Drobniewski, F; Evans, CA; Kummik, T; Mitchell, S; Nikolayevskyy, V; Toit, K | 1 |
| Baldan, HM; Brunetti, IL; Campos, ML; Davanço, MG; de Pontes Machado, DV; Filho, MA; Padilha, EC; Peccinini, RG; Pires, RV | 1 |
| Patsche, CB; Svensson, E; Wejse, C | 1 |
| Bhardwaj, A; Goyal, AK; Grobler, A; Mehta, A; Mehta, S; Singh, SK; Yadav, S | 1 |
| Bhardwaj, A; Goyal, AK; Grobler, A; Jain, AK; Mehta, A; Rath, G | 1 |
| Allnutt, JC; Bacon, J; Bottley, G; Doris, KS; Hatch, KA; Hendon-Dunn, CL; Marriott, AA; Marsh, PD; Taylor, SC; Thomas, SR; Watson, RJ | 1 |
| Gonzalez-Juarrero, M; Jackson, M; Lee, RE; Li, W; North, EJ; Obregón-Henao, A; Schnappinger, D; Wallach, JB | 1 |
| Clifton, DA; Crook, DW; Iqbal, Z; Niehaus, KE; Peto, TEA; Smith, EG; Walker, AS; Walker, TM; Wilson, DJ; Yang, Y; Zhu, T | 1 |
| Balada-Llasat, JM; Evans, CA; Gelaw, B; Kelley, HV; Shibabaw, A; Tesfaye, E; Tessema, B; Torrelles, JB; Wang, SH | 1 |
| Alsayed, SSR; Bishai, WR; Gunosewoyo, H; Lun, S; Payne, A | 1 |
| Bhagat, DS; Bhosale, D; Borade, RM; Mali, SN; Thorat, BR; Wavhal, SS | 1 |
11 review(s) available for ciprofloxacin and isoniazid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Recently reported biological activities of pyrazole compounds.
Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Pyrazoles | 2017 |
Fluoroquinolone derivatives and their anti-tubercular activities.
Topics: Animals; Antitubercular Agents; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis | 2018 |
Recent advances of imidazole-containing derivatives as anti-tubercular agents.
Topics: Animals; Antitubercular Agents; Dose-Response Relationship, Drug; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis | 2018 |
Benzofuran derivatives and their anti-tubercular, anti-bacterial activities.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Benzofurans; Humans; Structure-Activity Relationship | 2019 |
Fluoroquinolone-isatin hybrids and their biological activities.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Antitubercular Agents; Antiviral Agents; Fluoroquinolones; Humans; Isatin; Structure-Activity Relationship | 2019 |
Insights of synthetic analogues of anti-leprosy agents.
Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship | 2019 |
Antitubercular properties of thiazolidin-4-ones - A review.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Structure-Activity Relationship; Thiazolidines; THP-1 Cells; Vero Cells | 2021 |
Emerging impact of triazoles as anti-tubercular agent.
Topics: Antitubercular Agents; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles; Tuberculosis | 2022 |
Mycobacterium szulgai infection of the lung: case report and review of an unusual pathogen.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Lung Diseases; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium; Mycobacterium Infections; Radiography; Rifampin | 1997 |
[Value of ciprofloxacin in the therapy of tuberculosis and other mycobacterioses].
Topics: Anti-Infective Agents; Ciprofloxacin; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium Infections; Ofloxacin; Rifampin | 1997 |
5 trial(s) available for ciprofloxacin and isoniazid
| Article | Year |
|---|---|
Early bactericidal and sterilizing activities of ciprofloxacin in pulmonary tuberculosis.
Topics: Adult; Aged; Ciprofloxacin; Drug Therapy, Combination; Ethambutol; Female; HIV Seropositivity; HIV-1; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1993 |
Randomized controlled trial of a drug regimen that includes ciprofloxacin for the treatment of pulmonary tuberculosis.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Ethambutol; Female; HIV-1; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin; Time Factors; Tuberculosis, Pulmonary | 1996 |
The early bactericidal activity of ciprofloxacin in patients with pulmonary tuberculosis.
Topics: Adult; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Colony Count, Microbial; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Sputum; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 1997 |
A novel method for evaluating the antimicrobial activity of tuberculosis treatment regimens.
Topics: Antitubercular Agents; Cell Survival; Ciprofloxacin; Drug Administration Schedule; Humans; Isoniazid; Microbial Sensitivity Tests; Models, Statistical; Rifampin; Sputum; Tuberculosis, Pulmonary | 2003 |
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Injections, Intramuscular; Isoniazid; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal; Young Adult | 2011 |
176 other study(ies) available for ciprofloxacin and isoniazid
| Article | Year |
|---|---|
Antituberculous activity of some aryl semicarbazone derivatives.
Topics: Antitubercular Agents; Microbial Sensitivity Tests; Molecular Conformation; Molecular Structure; Mycobacterium tuberculosis; Semicarbazones; Structure-Activity Relationship | 2004 |
Identification of heteroarylenamines as a new class of antituberculosis lead molecules.
Topics: Amines; Antitubercular Agents; Drug Evaluation, Preclinical; Drug Resistance; Inhibitory Concentration 50; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen | 2007 |
A new modification of anti-tubercular active molecules.
Topics: Antitubercular Agents; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Half-Life; Isoniazid; Kinetics; Lipids; Microbial Sensitivity Tests; Mycobacterium avium; Mycobacterium kansasii; Pyrazinamide; Quantitative Structure-Activity Relationship | 2007 |
Hybrid molecules of estrone: new compounds with potential antibacterial, antifungal, and antiproliferative activities.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Antitubercular Agents; Bacteria; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatography, Thin Layer; Estrone; Fungi; Heterocyclic Compounds; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Spectrophotometry, Infrared | 2007 |
Antimycobacterial activities of novel 1-(cyclopropyl/tert-butyl/4-fluorophenyl)-1,4-dihydro- 6-nitro-4-oxo-7-(substituted secondary amino)-1,8-naphthyridine-3-carboxylic acid.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Drug Resistance, Multiple, Bacterial; Female; Light; Mice; Microbial Sensitivity Tests; Mycobacterium smegmatis; Mycobacterium tuberculosis; Naphthyridines; Structure-Activity Relationship; Topoisomerase II Inhibitors; Vero Cells | 2007 |
Synthesis of new 4-pyrrol-1-yl benzoic acid hydrazide analogs and some derived oxadiazole, triazole and pyrrole ring systems: a novel class of potential antibacterial and antitubercular agents.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Benzoic Acid; Drug Design; Mycobacterium tuberculosis; Oxadiazoles; Pyrroles; Triazoles | 2008 |
Evaluation of a 2-pyridone, KRQ-10018, against Mycobacterium tuberculosis in vitro and in vivo.
Topics: Animals; Antitubercular Agents; Biological Availability; Interferon-gamma; Mice; Mice, Inbred C57BL; Mice, Knockout; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyridones; Quinolones; Treatment Outcome; Tuberculosis, Pulmonary | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Discovery of antimycobacterial spiro-piperidin-4-ones: an atom economic, stereoselective synthesis, and biological intervention.
Topics: Antitubercular Agents; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Piperidines; Stereoisomerism | 2008 |
Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics.
Topics: Antitubercular Agents; BCG Vaccine; Microbial Sensitivity Tests; Mycobacterium bovis | 2009 |
5-Nitrofuran-2-yl derivatives: synthesis and inhibitory activities against growing and dormant mycobacterium species.
Topics: Antitubercular Agents; Combinatorial Chemistry Techniques; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitrofurans; Structure-Activity Relationship; Thiosemicarbazones; Tuberculosis | 2009 |
Synthesis, spectral and biological evaluation of some new thiazolidinones and thiazoles based on t-3-alkyl-r-2,c-6-diarylpiperidin-4-ones.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Bacteria; Fungi; Microbial Sensitivity Tests; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2009 |
Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs.
Topics: Antitubercular Agents; Disinfectants; Drug Resistance, Bacterial; Glutaral; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Mycobacterium chelonae; Mycobacterium smegmatis; o-Phthalaldehyde; Porins | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Synthesis of new 4-isopropylthiazole hydrazide analogs and some derived clubbed triazole, oxadiazole ring systems--a novel class of potential antibacterial, antifungal and antitubercular agents.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antitubercular Agents; Bacteria; Cell Line, Tumor; Cell Survival; Fungi; Humans; Hydrazines; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Thiazoles | 2009 |
Novel three-component domino reactions of ketones, isatin and amino acids: synthesis and discovery of antimycobacterial activity of highly functionalised novel dispiropyrrolidines.
Topics: Amino Acids; Anti-Bacterial Agents; Isatin; Ketones; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Mycobacterium tuberculosis; Pyrrolidines | 2010 |
1,3-Dipolar cycloaddition of C-aryl-N-phenylnitrones to (R)-1-(1-phenylethyl)-3-[(E)-arylmethylidene]tetrahydro-4(1H)-pyridinones: synthesis and antimycobacterial evaluation of enantiomerically pure spiroisoxazolidines.
Topics: Anti-Bacterial Agents; Drug Discovery; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Mycobacterium tuberculosis; Nitrogen Oxides; Oxazoles; Pyridones; Stereoisomerism | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
New 1,3-oxazolo[4,5-c]quinoline derivatives: synthesis and evaluation of antibacterial and antituberculosis properties.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Crystallography, X-Ray; Escherichia coli; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Oxazoles; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus | 2010 |
Antimycobacterial flavonoids from the leaf extract of Galenia africana.
Topics: Antitubercular Agents; Flavonoids; Humans; Magnoliopsida; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; NADH, NADPH Oxidoreductases; NADPH Oxidases; Plant Leaves; Plants, Medicinal; South Africa; Stereoisomerism | 2009 |
Synthesis of some novel 2-substituted-5-[isopropylthiazole] clubbed 1,2,4-triazole and 1,3,4-oxadiazoles as potential antimicrobial and antitubercular agents.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Antitubercular Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Triazoles | 2010 |
Anti-infective discorhabdins from a deep-water alaskan sponge of the genus Latrunculia.
Topics: Alkaloids; Animals; Anti-Infective Agents; Antimalarials; Antiprotozoal Agents; Hepacivirus; Heterocyclic Compounds, 4 or More Rings; Mice; Microbial Sensitivity Tests; Molecular Structure; Oceans and Seas; Plasmodium berghei; Plasmodium falciparum; Porifera; Quinones; Spiro Compounds | 2010 |
New quinoline derivatives: synthesis and investigation of antibacterial and antituberculosis properties.
Topics: Antitubercular Agents; Bacteria; Crystallography, X-Ray; Microbial Sensitivity Tests; Quinolines | 2010 |
Synthesis and pharmacological evaluation of clubbed isopropylthiazole derived triazolothiadiazoles, triazolothiadiazines and mannich bases as potential antimicrobial and antitubercular agents.
Topics: Anti-Infective Agents; Antitubercular Agents; Bacteria; Fungi; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Spectrophotometry, Infrared; Thiazoles | 2010 |
Synthesis and antitubercular activities of substituted benzoic acid N'-(substituted benzylidene/furan-2-ylmethylene)-N-(pyridine-3-carbonyl)-hydrazides.
Topics: Antitubercular Agents; Benzoic Acid; Dose-Response Relationship, Drug; Hydrazones; Molecular Structure; Mycobacterium tuberculosis; Stereoisomerism; Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A regio- and stereoselective 1,3-dipolar cycloaddition for the synthesis of novel spiro-pyrrolothiazolyloxindoles and their antitubercular evaluation.
Topics: Antitubercular Agents; Cyclization; Indoles; Microbial Sensitivity Tests; Molecular Conformation; Mycobacterium tuberculosis; Oxindoles; Spiro Compounds; Stereoisomerism | 2010 |
A facile 1,3-dipolar cycloaddition of azomethine ylides to 2-arylidene-1,3-indanediones: synthesis of dispiro-oxindolylpyrrolothiazoles and their antimycobacterial evaluation.
Topics: Antitubercular Agents; Azo Compounds; Crystallography, X-Ray; Indans; Microbial Sensitivity Tests; Molecular Conformation; Mycobacterium tuberculosis; Spiro Compounds; Stereoisomerism; Thiazoles; Thiosemicarbazones | 2010 |
Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl-4(1H)-quinolones.
Topics: Antitubercular Agents; Cell Line; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Quinolones | 2011 |
Synthesis and in vitro antimycobacterial activity of 8-OCH(3) ciprofloxacin methylene and ethylene isatin derivatives.
Topics: Animals; Anti-Bacterial Agents; Chlorocebus aethiops; Ciprofloxacin; Isatin; Microbial Sensitivity Tests; Mycobacterium; Oximes; Semicarbazones; Vero Cells | 2011 |
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
Topics: Antitubercular Agents; Carbohydrates; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxidoreductases; Thiocarbamates; Thioglucosides | 2011 |
Design, synthesis, and biological evaluation of new cinnamic derivatives as antituberculosis agents.
Topics: Amides; Antitubercular Agents; Cinnamates; Crystallography, X-Ray; Drug Design; Drug Resistance, Bacterial; Hydrazines; Isoniazid; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Mycolic Acids; Phthalazines; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2011 |
Synthesis of N-substituted 2-[(1E)-alkenyl]-4-(1H)-quinolone derivatives as antimycobacterial agents against non-tubercular mycobacteria.
Topics: Anti-Bacterial Agents; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Quinolones; Stereoisomerism; Structure-Activity Relationship | 2011 |
New quinolin-4-yl-1,2,3-triazoles carrying amides, sulphonamides and amidopiperazines as potential antitubercular agents.
Topics: Amides; Antitubercular Agents; Crystallography, X-Ray; Dose-Response Relationship, Drug; Escherichia coli; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Piperazines; Pseudomonas; Quinolines; Stereoisomerism; Streptococcus; Structure-Activity Relationship; Triazoles | 2011 |
A green expedient synthesis of pyridopyrimidine-2-thiones and their antitubercular activity.
Topics: Antitubercular Agents; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrimidines; Thiones | 2011 |
Synthesis, structure-activity relationship of novel substituted 4H-chromen-1,2,3,4-tetrahydropyrimidine-5-carboxylates as potential anti-mycobacterial and anticancer agents.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Carboxylic Acids; Cell Line, Tumor; Cell Survival; Chromans; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Molecular Structure; Mycobacterium tuberculosis; Pyrimidines; Structure-Activity Relationship | 2011 |
Antimycobacterial activity of novel 1,2,4-oxadiazole-pyranopyridine/chromene hybrids generated by chemoselective 1,3-dipolar cycloadditions of nitrile oxides.
Topics: Antibiotics, Antitubercular; Benzopyrans; Microbial Sensitivity Tests; Molecular Conformation; Mycobacterium tuberculosis; Nitriles; Oxadiazoles; Oxides; Pyridines; Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Synthesis and antimycobacterial activity of highly functionalized tetrahydro-4(1H)-pyridinones.
Topics: Anti-Bacterial Agents; Crystallography, X-Ray; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium tuberculosis; Pyridones | 2011 |
A facile four-component sequential protocol in the expedient synthesis of novel 2-aryl-5-methyl-2,3-dihydro-1H-3-pyrazolones in water and their antitubercular evaluation.
Topics: Antitubercular Agents; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium tuberculosis; Pyrazolones; Water | 2011 |
Synthesis of various 3-nitropropionamides as Mycobacterium tuberculosis isocitrate lyase inhibitor.
Topics: Anilides; Catalytic Domain; Chemistry Techniques, Synthetic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isocitrate Lyase; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Nitro Compounds; Stereoisomerism; Structure-Activity Relationship | 2011 |
New fluorine-containing hydrazones active against MDR-tuberculosis.
Topics: Animals; Antitubercular Agents; Cell Line; Fluorine; Humans; Hydrazones; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium kansasii; Plasma; Rats; Tuberculosis, Multidrug-Resistant | 2011 |
Synthesis of 3-heteroarylthioquinoline derivatives and their in vitro antituberculosis and cytotoxicity studies.
Topics: Animals; Antitubercular Agents; Humans; Mice; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium tuberculosis; NIH 3T3 Cells; Quinolines; Structure-Activity Relationship; Thiadiazoles; Tuberculosis | 2011 |
Design, synthesis and docking studies of quinoline-oxazolidinone hybrid molecules and their antitubercular properties.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Bacteria; Catalytic Domain; Drug Design; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Humans; Models, Molecular; Mycobacterium tuberculosis; Oxazolidinones; Protein Binding; Quinolines; Tuberculosis | 2011 |
Design, synthesis and docking studies of new quinoline-3-carbohydrazide derivatives as antitubercular agents.
Topics: Antitubercular Agents; Bacteria; Drug Design; Hydrazines; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Quinolines | 2011 |
Synthesis and biological evaluation of novel pyrazole derivatives with anticancer activity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Chemistry Techniques, Synthetic; Cyclin-Dependent Kinase Inhibitor p21; Drug Evaluation, Preclinical; Humans; Indoles; Mice; Microtubules; Models, Molecular; Protein Multimerization; Protein Structure, Quaternary; Pyrazoles; Tubulin; Tumor Suppressor Protein p53 | 2011 |
A facile synthesis of carbocycle-fused mono and bis-1,2,3-selenadiazoles and their antimicrobial and antimycobacterial studies.
Topics: Anti-Bacterial Agents; Azoles; Candida albicans; Chemistry Techniques, Synthetic; Microbial Sensitivity Tests; Mycobacterium tuberculosis | 2011 |
Chemical synthesis, biological evaluation and structure-activity relationship analysis of azaisoindolinones, a novel class of direct enoyl-ACP reductase inhibitors as potential antimycobacterial agents.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cell Line; Enzyme Inhibitors; Humans; Indoles; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxidoreductases; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Structure-Activity Relationship | 2011 |
1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study.
Topics: Antifungal Agents; Antitubercular Agents; Chemistry Techniques, Synthetic; Drug Design; Fungi; Indoles; Microbial Sensitivity Tests; Mycobacterium tuberculosis | 2011 |
Molecular properties prediction and synthesis of novel 1,3,4-oxadiazole analogues as potent antimicrobial and antitubercular agents.
Topics: Administration, Oral; Anti-Infective Agents; Antitubercular Agents; Bacteria; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxadiazoles; Software; Structure-Activity Relationship | 2011 |
Camphorsulfonic acid catalysed facile tandem double Friedlander annulation protocol for the synthesis of phenoxy linked bisquinoline derivatives and discovery of antitubercular agents.
Topics: Animals; Antitubercular Agents; Camphor; Catalysis; Chemistry Techniques, Synthetic; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Phenols; Quinolines; Structure-Activity Relationship | 2012 |
Design, synthesis of some new (2-aminothiazol-4-yl)methylester derivatives as possible antimicrobial and antitubercular agents.
Topics: Anti-Infective Agents; Antitubercular Agents; Bacteria; Bacterial Infections; Crystallography, X-Ray; Fungi; Humans; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium tuberculosis; Mycoses; Thiazoles; Tuberculosis | 2012 |
Anti-mycobacterial activities of some cationic and anionic calix[4]arene derivatives.
Topics: 2,2'-Dipyridyl; Anions; Antitubercular Agents; Calixarenes; Guanidine; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phenols; Quaternary Ammonium Compounds; Tuberculosis | 2012 |
Compounds of Alpinia katsumadai as potential efflux inhibitors in Mycobacterium smegmatis.
Topics: Alpinia; Antibiotics, Antitubercular; Antitubercular Agents; Diarylheptanoids; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium smegmatis; Plant Extracts; Seeds | 2012 |
Synthesis of benzimidazolyl-1,3,4-oxadiazol-2ylthio-N-phenyl (benzothiazolyl) acetamides as antibacterial, antifungal and antituberculosis agents.
Topics: Antifungal Agents; Antitubercular Agents; Bacteria; Benzothiazoles; Chemistry Techniques, Synthetic; Fungi; Microbial Sensitivity Tests; Mycobacterium tuberculosis | 2012 |
A solvent free, four-component synthesis and 1,3-dipolar cycloaddition of 4(H)-pyrans with nitrile oxides: synthesis and discovery of antimycobacterial activity of enantiomerically pure 1,2,4-oxadiazoles.
Topics: Anti-Bacterial Agents; Chemistry Techniques, Synthetic; Drug Discovery; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitriles; Oxadiazoles; Oxides; Piperidines; Pyrans; Stereoisomerism | 2012 |
An improved microwave assisted one-pot synthesis, and biological investigations of some novel aryldiazenyl chromeno fused pyrrolidines.
Topics: Antifungal Agents; Antitubercular Agents; Aspergillus fumigatus; Azo Compounds; Benzopyrans; Candida albicans; Crystallography, X-Ray; Gram-Negative Bacteria; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microwaves; Molecular Structure; Mycobacterium tuberculosis; Pyrrolidines; Stereoisomerism; Thiosemicarbazones | 2012 |
New N-arylamino biquinoline derivatives: synthesis, antimicrobial, antituberculosis, and antimalarial evaluation.
Topics: Antimalarials; Antitubercular Agents; Chemistry Techniques, Synthetic; Electrons; Fungi; Hydrophobic and Hydrophilic Interactions; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Plasmodium falciparum; Quinolines | 2012 |
Green synthesis and anti-infective activities of fluorinated pyrazoline derivatives.
Topics: Anti-Infective Agents; Antitubercular Agents; Bacteria; Bacterial Infections; Fungi; Green Chemistry Technology; Halogenation; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Mycoses; Pyrazoles; Tuberculosis | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Synthesis and evaluation of novel 1,3,4-oxadiazole derivatives of marine bromopyrrole alkaloids as antimicrobial agent.
Topics: Alkaloids; Anti-Infective Agents; Antitubercular Agents; Bacteria; Bacterial Infections; Fungi; Halogenation; Humans; Microbial Sensitivity Tests; Mycoses; Oxadiazoles; Pyrroles | 2012 |
An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles.
Topics: Aldehydes; Anti-Bacterial Agents; Coumarins; Gram-Negative Bacteria; Gram-Positive Bacteria; Heterocyclic Compounds; Ionic Liquids; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrans; Pyrazolones; Quinolines; Structure-Activity Relationship | 2013 |
Synthesis and identification of β-aryloxyquinoline based diversely fluorine substituted N-aryl quinolone derivatives as a new class of antimicrobial, antituberculosis and antioxidant agents.
Topics: Animals; Anti-Infective Agents; Antioxidants; Antitubercular Agents; Artemia; Aspergillus fumigatus; Candida albicans; Dose-Response Relationship, Drug; Fluorine; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Models, Chemical; Molecular Structure; Mycobacterium tuberculosis; Ovum; Quinolines; Structure-Activity Relationship | 2013 |
3-Anhydro-6-hydroxy-ophiobolin A, a new sesterterpene inhibiting the growth of methicillin-resistant Staphylococcus aureus and inducing the cell death by apoptosis on K562, from the phytopathogenic fungus Bipolaris oryzae.
Topics: Apoptosis; Cell Death; Drug Screening Assays, Antitumor; Flow Cytometry; Hep G2 Cells; Humans; K562 Cells; Methicillin-Resistant Staphylococcus aureus; Oryza; Sesterterpenes; Structure-Activity Relationship | 2013 |
Design and synthesis of biquinolone-isoniazid hybrids as a new class of antitubercular and antimicrobial agents.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antitubercular Agents; Artemia; Bacteria; Dose-Response Relationship, Drug; Drug Design; Fungi; Isoniazid; Microbial Sensitivity Tests; Molecular Structure; Motor Activity; Quinolones; Structure-Activity Relationship; Tuberculosis | 2013 |
Design and synthesis of positional isomers of 5 and 6-bromo-1-[(phenyl)sulfonyl]-2-[(4-nitrophenoxy)methyl]-1H-benzimidazoles as possible antimicrobial and antitubercular agents.
Topics: Anti-Bacterial Agents; Antifungal Agents; Aspergillus flavus; Benzimidazoles; Candida albicans; Dose-Response Relationship, Drug; Drug Design; Escherichia coli; Klebsiella pneumoniae; Models, Molecular; Molecular Structure; Mycobacterium; Rhizopus; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
New derivatives of salicylamides: Preparation and antimicrobial activity against various bacterial species.
Topics: Ampicillin; Anti-Infective Agents; Ciprofloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Salicylamides; Structure-Activity Relationship | 2013 |
Synthesis and evaluation of novel 4-nitropyrrole-based 1,3,4-oxadiazole derivatives as antimicrobial and anti-tubercular agents.
Topics: Animals; Antibiotics, Antitubercular; Antifungal Agents; Bacillus subtilis; Candida albicans; Chlorocebus aethiops; Dose-Response Relationship, Drug; Escherichia coli; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Pyrroles; Staphylococcus aureus; Structure-Activity Relationship; Vero Cells | 2013 |
Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Streptomyces; Vero Cells | 2013 |
Synthesis and characterization of new N-(4-(4-chloro-1H-imidazol-1-yl)-3-methoxyphenyl)amide/sulfonamide derivatives as possible antimicrobial and antitubercular agents.
Topics: Amides; Anti-Infective Agents; Antitubercular Agents; Bacteria; Bacterial Infections; Fungi; Humans; Imidazoles; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Mycoses; Structure-Activity Relationship; Sulfonamides | 2014 |
Alkylamino derivatives of pyrazinamide: synthesis and antimycobacterial evaluation.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antitubercular Agents; Crystallography; Drug Evaluation, Preclinical; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide | 2014 |
Development of antimycobacterial tetrahydrothieno[2,3-c]pyridine-3-carboxamides and hexahydrocycloocta[b]thiophene-3-carboxamides: Molecular modification from known antimycobacterial lead.
Topics: Antitubercular Agents; Drug Design; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Structure-Activity Relationship; Thiophenes | 2014 |
Synthesis and antimycobacterial activities of some new thiazolylhydrazone derivatives.
Topics: Anti-Bacterial Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Hydrazones; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Thiazoles | 2014 |
Synthesis, characterization and pharmacological screening of some novel 5-imidazopyrazole incorporated polyhydroquinoline derivatives.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Bacteria; Dose-Response Relationship, Drug; Fungi; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymers; Pyrazoles; Quinolines; Structure-Activity Relationship | 2014 |
Novel N-linked aminopiperidine-based gyrase inhibitors with improved hERG and in vivo efficacy against Mycobacterium tuberculosis.
Topics: Acute Disease; Administration, Oral; Animals; Antitubercular Agents; Bacterial Proteins; Biological Availability; Chronic Disease; DNA Gyrase; Drug Resistance, Bacterial; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Humans; Macrophages; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Piperidines; Protein Subunits; Rats; Stereoisomerism; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tuberculosis, Pulmonary | 2014 |
Studies on molecular properties prediction, antitubercular and antimicrobial activities of novel quinoline based pyrimidine motifs.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Bacteria; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Pyrimidines; Quinolines; Structure-Activity Relationship | 2014 |
Synthesis of novel 4-nitropyrrole-based semicarbazide and thiosemicarbazide hybrids with antimicrobial and anti-tubercular activity.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Dose-Response Relationship, Drug; Escherichia coli; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrroles; Semicarbazides; Staphylococcus aureus; Structure-Activity Relationship | 2014 |
Synthesis, antibacterial and antitubercular activities of benzimidazole bearing substituted 2-pyridone motifs.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Benzimidazoles; Cell Proliferation; Chlorocebus aethiops; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Pyridones; Structure-Activity Relationship; Vero Cells | 2014 |
Design, synthesis and characterization of fluoro substituted novel pyrazolylpyrazolines scaffold and their pharmacological screening.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Bacteria; Dose-Response Relationship, Drug; Drug Design; Fungi; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrazoles; Structure-Activity Relationship | 2014 |
Design, synthesis and anti-mycobacterial activity of 1,2,3,5-tetrasubstituted pyrrolyl-N-acetic acid derivatives.
Topics: Acetates; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Design; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrroles; Structure-Activity Relationship | 2014 |
Benzimidazoles: novel mycobacterial gyrase inhibitors from scaffold morphing.
Topics: | 2014 |
Synthesis, antimycobacterial and antibacterial evaluation of l-[(1R, 2S)-2-fluorocyclopropyl]fluoroquinolone derivatives containing an oxime functional moiety.
Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Fluoroquinolones; Microbial Sensitivity Tests; Molecular Structure; Oximes; Structure-Activity Relationship | 2014 |
Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives.
Topics: Animals; Anti-Bacterial Agents; Chalcones; Chemistry Techniques, Synthetic; Chlorocebus aethiops; Chromones; DNA Gyrase; DNA Topoisomerase IV; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phloroglucinol; Structure-Activity Relationship; Topoisomerase II Inhibitors; Vero Cells | 2014 |
Syntheses and Antituberculosis Activity of 1,3-Benzothiazinone Sulfoxide and Sulfone Derived from BTZ043.
Topics: | 2015 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |
Synthesis and anti-mycobacterial activity of 2-chloronicotinaldehydes based novel 1H-1,2,3-triazolylbenzohydrazides.
Topics: Aldehydes; Animals; Antitubercular Agents; Cell Line; Hydrazines; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis | 2015 |
Synthesis, cytotoxicity and antimicrobial activity of thiourea derivatives incorporating 3-(trifluoromethyl)phenyl moiety.
Topics: Aniline Compounds; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Cell Line; Cell Proliferation; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Fungi; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Thiourea; Topoisomerase Inhibitors | 2015 |
Left-Hand Side Exploration of Novel Bacterial Topoisomerase Inhibitors to Improve Selectivity against hERG Binding.
Topics: | 2015 |
Combating highly resistant emerging pathogen Mycobacterium abscessus and Mycobacterium tuberculosis with novel salicylanilide esters and carbamates.
Topics: Anti-Bacterial Agents; Carbamates; Cell Line; Dose-Response Relationship, Drug; Esters; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Salicylanilides; Structure-Activity Relationship; Tuberculosis, Multidrug-Resistant | 2015 |
Synthesis and biological evaluation of phaitanthrin congeners as anti-mycobacterial agents.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Indoles; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Quinazolinones; Structure-Activity Relationship | 2015 |
Guanidinium compounds with sub-micromolar activities against Mycobacterium tuberculosis. Synthesis, characterization and biological evaluations.
Topics: Antitubercular Agents; Guanidine; Humans; Models, Molecular; Mycobacterium tuberculosis; Tuberculosis | 2015 |
Design of novel dispirooxindolopyrrolidine and dispirooxindolopyrrolothiazole derivatives as potential antitubercular agents.
Topics: Animals; Antitubercular Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrrolidines; Spiro Compounds; Structure-Activity Relationship; Thiazoles | 2015 |
Re-engineering nalidixic acid's chemical scaffold: A step towards the development of novel anti-tubercular and anti-bacterial leads for resistant pathogens.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Escherichia coli; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nalidixic Acid; Proteus vulgaris; Structure-Activity Relationship | 2015 |
Synthesis, antimycobacterial and antibacterial activity of fluoroquinolone derivatives containing an 3-alkoxyimino-4-(cyclopropylanimo)methylpyrrolidine moiety.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enterococcus; Fluoroquinolones; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrrolidines; Structure-Activity Relationship; Tuberculosis, Multidrug-Resistant | 2015 |
Synthesis, antimycobacterial and antibacterial activity of l-[(1R,2S)-2-fluorocyclopropyl]naphthyridone derivatives containing an oxime-functionalized pyrrolidine moiety.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Levofloxacin; Moxifloxacin; Naphthyridines; Oximes; Pyrrolidines; Stereoisomerism | 2015 |
New INH-pyrazole analogs: Design, synthesis and evaluation of antitubercular and antibacterial activity.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Bacteria; Binding Sites; Drug Design; Inhibitory Concentration 50; Isoniazid; Microbial Sensitivity Tests; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Pyrazoles | 2015 |
Design of new phenothiazine-thiadiazole hybrids via molecular hybridization approach for the development of potent antitubercular agents.
Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Design; Escherichia coli; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Phenothiazines; Pseudomonas aeruginosa; Staphylococcus aureus; Structure-Activity Relationship; Thiadiazoles; Vero Cells | 2015 |
Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities.
Topics: Anti-Infective Agents; Antimalarials; Antitubercular Agents; Bacteria; Bacterial Infections; Fungi; Humans; Malaria, Falciparum; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Mycoses; Plasmodium falciparum; Pyrazoles; Quinolines; Structure-Activity Relationship; Tuberculosis | 2016 |
Synthesis, antimycobacterial and antibacterial activity of 1-(6-amino-3,5-difluoropyridin-2-yl)fluoroquinolone derivatives containing an oxime functional moiety.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Fluoroquinolones; Oximes | 2016 |
Benzo[d]thiazol-2-yl(piperazin-1-yl)methanones as new anti-mycobacterial chemotypes: Design, synthesis, biological evaluation and 3D-QSAR studies.
Topics: Animals; Antitubercular Agents; Chemistry Techniques, Synthetic; Drug Design; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Mycobacterium tuberculosis; Piperazine; Piperazines; Quantitative Structure-Activity Relationship; RAW 264.7 Cells | 2016 |
Synthesis, biological evaluation and structure-activity relationship of 2-styrylquinazolones as anti-tubercular agents.
Topics: Antitubercular Agents; Cell Survival; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Quinazolines; Structure-Activity Relationship | 2016 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Design, development of new synthetic methodology, and biological evaluation of substituted quinolines as new anti-tubercular leads.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Quinolines; Structure-Activity Relationship; Tuberculosis | 2016 |
Synthesis, screening and docking analysis of hispolon analogs as potential antitubercular agents.
Topics: Antitubercular Agents; Catechols; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2017 |
Synthesis, identification and in vitro biological evaluation of some novel quinoline incorporated 1,3-thiazinan-4-one derivatives.
Topics: Anti-Bacterial Agents; Antimalarials; Antitubercular Agents; Clostridium tetani; Gram-Negative Bacteria; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Plasmodium falciparum; Quinolines; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Thiazines | 2017 |
A robust synthesis of functionalized 2H-indazoles via solid state melt reaction (SSMR) and their anti-tubercular activity.
Topics: Antitubercular Agents; Ciprofloxacin; Ethambutol; Indazoles; Isoniazid; Mycobacterium tuberculosis; Rifampin; Structure-Activity Relationship | 2017 |
Design, synthesis and 2D QSAR study of novel pyridine and quinolone hydrazone derivatives as potential antimicrobial and antitubercular agents.
Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Cell Line; Dose-Response Relationship, Drug; Drug Design; Fibroblasts; Fungi; Humans; Hydrazones; Microbial Sensitivity Tests; Molecular Structure; Pyridines; Quantitative Structure-Activity Relationship; Quinolones | 2017 |
Primaquine hybrids as promising antimycobacterial and antimalarial agents.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Plasmodium berghei; Primaquine; Rats; Structure-Activity Relationship | 2018 |
Amino acid conjugated antimicrobial drugs: Synthesis, lipophilicity- activity relationship, antibacterial and urease inhibition activity.
Topics: Amino Acids; Anti-Bacterial Agents; Bacillus; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; Hydrophobic and Hydrophilic Interactions; Isoniazid; Metronidazole; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Salmonella typhi; Staphylococcus aureus; Structure-Activity Relationship; Trimethoprim; Urease | 2018 |
Synthesis and antimycobacterial activity of 1-(β-d-Ribofuranosyl)-4-coumarinyloxymethyl- / -coumarinyl-1,2,3-triazole.
Topics: Anti-Bacterial Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles | 2018 |
Benzo[d]thiazole-2-carbanilides as new anti-TB chemotypes: Design, synthesis, biological evaluation, and structure-activity relationship.
Topics: Animals; Antitubercular Agents; Carbanilides; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; RAW 264.7 Cells; Structure-Activity Relationship; Thiazoles | 2018 |
A novel synthesis of 2-arylbenzimidazoles in molecular sieves-MeOH system and their antitubercular activity.
Topics: Administration, Oral; Animals; Antitubercular Agents; Bacterial Proteins; Binding Sites; Body Weight; DNA Gyrase; Imidazoles; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Protein Structure, Tertiary; Structure-Activity Relationship | 2018 |
Design, synthesis, molecular-docking and antimycobacterial evaluation of some novel 1,2,3-triazolyl xanthenones.
Topics: | 2017 |
Design, synthesis and antimycobacterial activity of hybrid molecules combining pyrazinamide with a 4-phenylthiazol-2-amine scaffold.
Topics: | 2018 |
Novel indole-thiazolidinone conjugates: Design, synthesis and whole-cell phenotypic evaluation as a novel class of antimicrobial agents.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Cell Line; Dose-Response Relationship, Drug; Drug Design; Fungi; Humans; Indoles; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Phenotype; RAW 264.7 Cells; Structure-Activity Relationship; Thiazolidines | 2018 |
Synthesis, antituberculosis studies and biological evaluation of new quinoline derivatives carrying 1,2,4-oxadiazole moiety.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Microsomes, Liver; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Quinolines; Structure-Activity Relationship | 2019 |
Synthesis and biological evaluation of 1H-pyrrolo[2,3-d]pyrimidine-1,2,3-triazole derivatives as novel anti-tubercular agents.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Pyrimidines; Pyrroles; Structure-Activity Relationship; Triazoles | 2019 |
Synthesis of novel morpholine, thiomorpholine and N-substituted piperazine coupled 2-(thiophen-2-yl)dihydroquinolines as potent inhibitors of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Morpholines; Mycobacterium tuberculosis; Piperazine; Quinolines; Structure-Activity Relationship | 2019 |
Synthesis and evaluation of novel substituted 1,2,3-triazolyldihydroquinolines as promising antitubercular agents.
Topics: Antitubercular Agents; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Quinolines; Triazoles | 2019 |
Design, synthesis and anti-bacterial studies of piperazine derivatives against drug resistant bacteria.
Topics: Anti-Bacterial Agents; Bacteria; Chemistry Techniques, Synthetic; DNA Gyrase; Drug Design; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Piperazine; Protein Conformation | 2019 |
Molecular hybridization approach for phenothiazine incorporated 1,2,3-triazole hybrids as promising antimicrobial agents: Design, synthesis, molecular docking and in silico ADME studies.
Topics: Adsorption; Animals; Anti-Bacterial Agents; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Design; Escherichia coli; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Phenothiazines; Pseudomonas aeruginosa; Staphylococcus aureus; Structure-Activity Relationship; Triazoles; Vero Cells | 2019 |
Expansion of a novel lead targeting M. tuberculosis DHFR as antitubercular agents.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2019 |
5-Chloro-2-thiophenyl-1,2,3-triazolylmethyldihydroquinolines as dual inhibitors of Mycobacterium tuberculosis and influenza virus: Synthesis and evaluation.
Topics: Antitubercular Agents; Antiviral Agents; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Orthomyxoviridae; Structure-Activity Relationship | 2019 |
The synthesis and in vitro biological evaluation of novel fluorinated tetrahydrobenzo[j]phenanthridine-7,12-diones against Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Benzophenanthridines; Cell Line; Dose-Response Relationship, Drug; Humans; Hydrocarbons, Fluorinated; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2019 |
Development of (4-methoxyphenyl)-1H-tetrazol-5-amine regioisomers as a new class of selective antitubercular agents.
Topics: Amines; Antitubercular Agents; Cell Death; Cell Line; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Structure-Activity Relationship; Tetrazoles | 2020 |
Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Bacillus subtilis; Benzofurans; Lichens; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Triazoles | 2020 |
Novel benzimidazole-acrylonitrile hybrids and their derivatives: Design, synthesis and antimycobacterial activity.
Topics: Acrylonitrile; Anti-Bacterial Agents; Benzimidazoles; Dose-Response Relationship, Drug; Drug Design; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2020 |
4-Substituted picolinohydrazonamides as a new class of potential antitubercular agents.
Topics: Animals; Antitubercular Agents; Bacteria; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Pyridines; Thiosemicarbazones; Yeasts | 2020 |
Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation.
Topics: Animals; Antifungal Agents; Antitubercular Agents; Aspergillus niger; Bacterial Proteins; Drug Design; Gram-Negative Bacteria; Isoniazid; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; Protein Binding; RAW 264.7 Cells; Triazoles | 2020 |
Design and synthesis of purine connected piperazine derivatives as novel inhibitors of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Drug Design; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Piperazine; Purines; Structure-Activity Relationship | 2020 |
Synthesis and biological evaluation of anti-tubercular activity of Schiff bases of 2-Amino thiazoles.
Topics: Amination; Antitubercular Agents; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Schiff Bases; Thiazoles; Tuberculosis | 2020 |
Structure based design, synthesis, and biological evaluation of imidazole derivatives targeting dihydropteroate synthase enzyme.
Topics: Anti-Bacterial Agents; Dihydropteroate Synthase; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Imidazoles; Ligands; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin-Resistant Enterococci | 2021 |
Discovery of novel N
Topics: A549 Cells; Animals; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Cytidine; Drug Discovery; Fungi; Humans; Microbial Sensitivity Tests | 2021 |
Microwave assisted regioselective synthesis of quinoline appended triazoles as potent anti-tubercular and antifungal agents via copper (I) catalyzed cycloaddition.
Topics: Antifungal Agents; Antitubercular Agents; Aspergillus; Candida albicans; Catalysis; Cell Survival; Copper; Cycloaddition Reaction; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Microbial Sensitivity Tests; Microwaves; Molecular Structure; Mycobacterium tuberculosis; Quinolines; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2021 |
Design, synthesis and molecular docking studies of imidazole and benzimidazole linked ethionamide derivatives as inhibitors of InhA and antituberculosis agents.
Topics: Antitubercular Agents; Benzimidazoles; Dose-Response Relationship, Drug; Drug Design; Ethionamide; Humans; Imidazoles; Inhibins; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2022 |
Drug screening approach against mycobacterial fatty acyl-AMP ligase FAAL32 renews the interest of the salicylanilide pharmacophore in the fight against tuberculosis.
Topics: Adenosine Monophosphate; Antitubercular Agents; Drug Evaluation, Preclinical; Humans; Mycobacterium tuberculosis; Salicylanilides; Tuberculosis | 2022 |
Susceptibility of Mycobacterium kansasii to ethambutol and its combination with rifamycins, ciprofloxacin and isoniazid.
Topics: Ciprofloxacin; Drug Resistance, Microbial; Drug Synergism; Ethambutol; Isoniazid; Nontuberculous Mycobacteria; Rifamycins | 1992 |
Combination chemotherapy with ciprofloxacin for infection with Mycobacterium tuberculosis in mouse models.
Topics: Animals; Ciprofloxacin; Disease Models, Animal; Drug Therapy, Combination; Isoniazid; Male; Mice; Rifampin; Tuberculosis | 1989 |
In-vitro activity of six fluorinated quinolones against Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1987 |
In vitro susceptibility of Mycobacterium tuberculosis to ofloxacin and ciprofloxacin in combination with rifampin and isoniazid.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Synergism; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Oxazines; Rifampin | 1987 |
In vitro activity of ciprofloxacin in combination with standard antituberculous drugs against mycobacterium tuberculosis.
Topics: Antitubercular Agents; Ciprofloxacin; Ethambutol; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin | 1988 |
Effect of combined clofazimine and ansamycin therapy on Mycobacterium avium-Mycobacterium intracellulare bacteremia in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Amikacin; Anti-Bacterial Agents; Ciprofloxacin; Clofazimine; Cycloserine; Drug Therapy, Combination; Humans; Isoniazid; Lactams, Macrocyclic; Mycobacterium avium; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Sepsis | 1987 |
Hepatotoxicity associated with acetaminophen usage in patients receiving multiple drug therapy for tuberculosis.
Topics: Acetaminophen; Adult; Capreomycin; Ciprofloxacin; Drug Combinations; Drug Overdose; Ethambutol; Female; Humans; Isoniazid; Liver; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1994 |
Early bactericidal activity as a method of assessment of drugs for the treatment of tuberculosis.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Isoniazid; Microbial Sensitivity Tests; Predictive Value of Tests; Pyrazinamide; Rifabutin; Time Factors; Tuberculosis | 1994 |
Rifampin-resistant Mycobacterium kansasii.
Topics: Adult; Aged; Aged, 80 and over; Amikacin; Antitubercular Agents; Ciprofloxacin; Clinical Protocols; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Pyrazinamide; Pyridoxine; Rifampin; Streptomycin; Texas; Treatment Outcome; Tuberculosis | 1994 |
The management of mycobacterial infections in HIV seropositive individuals. Jefferiss Wing Therapeutics and Protocols Group.
Topics: Adrenal Cortex Hormones; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Clofazimine; Drug Therapy, Combination; Ethambutol; HIV Infections; Humans; Isoniazid; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Nontuberculous Mycobacteria; Practice Guidelines as Topic; Pyrazinamide; Pyridoxine; Radiography; Rifabutin; Rifampin; Tuberculosis, Meningeal; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1996 |
Evaluation of the post-antibiotic effect of six anti-mycobacterial agents against Mycobacterium avium by the Bactec radiometric method.
Topics: Amikacin; Antitubercular Agents; Cell Division; Ciprofloxacin; Clarithromycin; Drug Therapy, Combination; Ethambutol; Isoniazid; Microbial Sensitivity Tests; Mycobacterium avium; Radiometry; Rifampin | 1997 |
Evaluation of a bacteriophage-based assay (phage amplified biologically assay) as a rapid screen for resistance to isoniazid, ethambutol, streptomycin, pyrazinamide, and ciprofloxacin among clinical isolates of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Ciprofloxacin; Drug Resistance, Microbial; Ethambutol; Evaluation Studies as Topic; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacteriophages; Mycobacterium tuberculosis; Phenotype; Pyrazinamide; Streptomycin; Tuberculosis | 1999 |
Evaluation of Etest for susceptibility testing of Mycobacterium tuberculosis.
Topics: Agar; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin | 2000 |
A reiterative method for calculating the early bactericidal activity of antituberculosis drugs.
Topics: Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Clinical Trials as Topic; Colony Count, Microbial; Drug Evaluation; Humans; Isoniazid; Models, Biological; Mycobacterium tuberculosis; Regression Analysis; Sputum; Tuberculosis, Pulmonary | 2002 |
Drug-sensitivity profile of clinical Mycobacterium tuberculosis isolates--a retrospective study from a chest-disease institute in India.
Topics: Adult; Aged; Antitubercular Agents; Ciprofloxacin; Drug Resistance, Bacterial; Female; Humans; India; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Retrospective Studies; Rifampin; Sputum; Treatment Failure; Tuberculosis, Pulmonary | 2005 |
Determination of in vitro synergy when three antimicrobial agents are combined against Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Drug Synergism; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis | 2005 |
Mycobacterium kansasii: antibiotic susceptibility and PCR-restriction analysis of clinical isolates.
Topics: Amikacin; Anti-Bacterial Agents; Brazil; Ciprofloxacin; Clarithromycin; Clofazimine; Cycloserine; DNA Fingerprinting; DNA, Bacterial; Doxycycline; Drug Resistance, Bacterial; Ethambutol; Ethionamide; Genotype; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium Infections, Nontuberculous; Mycobacterium kansasii; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Rifabutin; Rifampin; Streptomycin | 2005 |
Evaluation of MGIT 960-based antimicrobial testing and determination of critical concentrations of first- and second-line antimicrobial drugs with drug-resistant clinical strains of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; In Vitro Techniques; Isoniazid; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Quinolines; Rifampin; Tuberculosis, Pulmonary | 2006 |
Evaluation of a tool to benchmark hospital antibiotic prescribing in the United Kingdom.
Topics: Anti-Bacterial Agents; Benchmarking; Cefuroxime; Ciprofloxacin; Cohort Studies; Data Collection; Drug Prescriptions; Drug Utilization; Hospitals; Humans; Isoniazid; Medication Systems, Hospital; Pharmacy Service, Hospital; Pilot Projects; Practice Guidelines as Topic; Practice Patterns, Physicians'; Rifampin; United Kingdom | 2008 |
Molecular detection of mutations associated with first- and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; Ciprofloxacin; Ethambutol; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin | 2011 |
Comparison of the bactericidal activity of various fluoroquinolones against Mycobacterium tuberculosis in an in vitro experimental model.
Topics: Antitubercular Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Spain; Tuberculosis | 2011 |
Bone marrow infection with Mycobacterium fortuitum in a diabetic patient.
Topics: Amikacin; Anti-Bacterial Agents; Antibiotics, Antitubercular; Bone Marrow; Bone Marrow Diseases; Ciprofloxacin; Diabetes Mellitus, Type 2; Humans; Isoniazid; Male; Middle Aged; Mycobacterium fortuitum; Mycobacterium Infections, Nontuberculous; Rifampin; Treatment Outcome | 2011 |
A simple and economical in-house phage technique for the rapid detection of rifampin, isoniazid, ethambutol, streptomycin, and ciprofloxacin drug resistance in Mycobacterium tuberculosis, directly on decontaminated sputum samples.
Topics: Adolescent; Adult; Aged; Antibiotics, Antitubercular; Ciprofloxacin; Ethambutol; Female; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Microbial Viability; Middle Aged; Mycobacteriophages; Mycobacterium tuberculosis; Rifampin; Sensitivity and Specificity; Sputum; Streptomycin; Tuberculosis, Multidrug-Resistant; Virus Replication; Young Adult | 2012 |
The Colour Test for drug susceptibility testing of Mycobacterium tuberculosis strains.
Topics: Antitubercular Agents; Ciprofloxacin; Color; Drug Resistance, Multiple, Bacterial; Estonia; Extensively Drug-Resistant Tuberculosis; Feasibility Studies; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Predictive Value of Tests; Rifampin; Sensitivity and Specificity; Time Factors; Tuberculosis, Multidrug-Resistant | 2012 |
In-house, simple & economical phage technique for rapid detection of rifampicin, isoniazid, ethambutol, streptomycin & ciprofloxacin drug resistance using Mycobacterium tuberculosis isolates.
Topics: Antitubercular Agents; Bacteriophages; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin; Sensitivity and Specificity; Streptomycin; Tuberculosis, Multidrug-Resistant | 2012 |
Pharmacokinetic and safety evaluation of the use of ciprofloxacin on an isoniazid-rifampicin regimen in rabbits.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antibiotics, Antitubercular; Aspartate Aminotransferases; Bilirubin; Ciprofloxacin; Drug Combinations; Isoniazid; Male; Rabbits; Rifampin | 2012 |
Disseminated Mycobacterium celatum disease with prolonged pulmonary involvement.
Topics: Aged; Anti-Bacterial Agents; Azithromycin; Ciprofloxacin; Clarithromycin; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Lung; Lung Diseases; Mycobacterium; Mycobacterium Infections; Pyrazinamide; Radiography | 2014 |
Pulmonary delivery of antitubercular drugs using spray-dried lipid-polymer hybrid nanoparticles.
Topics: Animals; Antitubercular Agents; Cell Line; Ciprofloxacin; Humans; Isoniazid; Lipids; Macrophages, Alveolar; Mice; Nanoparticles | 2016 |
Pulmonary Delivery of Anti-Tubercular Drugs Using Ligand Anchored pH Sensitive Liposomes for the Treatment of Pulmonary Tuberculosis.
Topics: Administration, Inhalation; Aniline Compounds; Animals; Antitubercular Agents; Cells, Cultured; Ciprofloxacin; Drug Carriers; Drug Combinations; Drug Liberation; Hydrogen-Ion Concentration; Isoniazid; Liposomes; Macrophages, Alveolar; Male; Mannosides; Mice; Powders; Tuberculosis, Pulmonary | 2016 |
A Flow Cytometry Method for Rapidly Assessing Mycobacterium tuberculosis Responses to Antibiotics with Different Modes of Action.
Topics: Antitubercular Agents; Ciprofloxacin; Flow Cytometry; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin | 2016 |
Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3.
Topics: Animals; Antitubercular Agents; Bacterial Load; Bacterial Proteins; Biological Transport; Ciprofloxacin; Disease Models, Animal; Doxycycline; Female; Gene Expression; Gene Knockdown Techniques; Humans; Isoniazid; Lung; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Microbial Viability; Mycobacterium tuberculosis; Mycolic Acids; Rifampin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2016 |
Machine learning for classifying tuberculosis drug-resistance from DNA sequencing data.
Topics: Antitubercular Agents; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Machine Learning; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant | 2018 |
MDR/XDR-TB Colour Test for drug susceptibility testing of Mycobacterium tuberculosis, Northwest Ethiopia.
Topics: Adolescent; Adult; Antitubercular Agents; Ciprofloxacin; Culture Media; Ethiopia; Extensively Drug-Resistant Tuberculosis; Female; Health Resources; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin; Sensitivity and Specificity; Sputum; Tuberculosis, Multidrug-Resistant; Young Adult | 2020 |
Facile synthesis and antimycobacterial activity of isoniazid, pyrazinamide and ciprofloxacin derivatives.
Topics: Animals; Antitubercular Agents; Binding Sites; Catalytic Domain; Cell Survival; Chlorocebus aethiops; Ciprofloxacin; DNA Gyrase; Drug Design; Drug Resistance, Bacterial; Isoniazid; Microbial Sensitivity Tests; Molecular Conformation; Molecular Docking Simulation; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Pyrazinamide; Structure-Activity Relationship; Vero Cells | 2021 |
Synthesis, Molecular Docking, and
Topics: Antitubercular Agents; Ciprofloxacin; Ethanol; Humans; Hydrazones; Isoniazid; Molecular Docking Simulation; Mycobacterium tuberculosis; Tuberculosis | 2022 |