ciprofloxacin has been researched along with indomethacin in 46 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (2.17) | 18.7374 |
1990's | 2 (4.35) | 18.2507 |
2000's | 20 (43.48) | 29.6817 |
2010's | 21 (45.65) | 24.3611 |
2020's | 2 (4.35) | 2.80 |
Authors | Studies |
---|---|
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
Caron, G; Ermondi, G | 1 |
Jolivette, LJ; Ward, KW | 1 |
Jolivette, LJ; Nagilla, R; Ward, KW | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Ashok, M; Holla, BS; Karegoudar, P; Mahalinga, M; Poojary, B; Prasad, DJ | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Aridoss, G; Jeong, YT; Kabilan, S; Parthiban, P; Prakash, M; Ramachandran, R | 1 |
Karthikeyan, MS | 1 |
el-Gazzar, AB; Hafez, HN; Nawwar, GA | 1 |
Abdel-Aziz, M; Abdel-Hafez, el-SM; Abuo-Rahma, Gel-D; Farag, HH; Radwan, MF | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Campillo, NE; Guerra, A; Páez, JA | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Avdeef, A; Tam, KY | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Sen, S; Sinha, N | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Nagi Reddy, M; Rajam, MV; Rajanarendar, E; Rama Krishna, S; Rama Murthy, K; Reddy, YN | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Bobade, VD; Mhaske, PC; Nandave, M; Narkhade, S; Shelke, SH; Walhekar, NM | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Rajasekaran, A; Senthilkumar, P; Sivakumar, KK; Wattamwar, PP | 1 |
Kaushik, D; Kaushik, P; Khloya, P; Kumar, S; Sharma, PK; Surain, P | 1 |
Bharate, SS; Vishwakarma, RA | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Bernardino, AMR; Boechat, N; Dos Santos, MS; Faria, JV; Miguita, AGC; Vegi, PF | 1 |
Capito, JE; El-Manawaty, MA; George, RF; Girgis, AS; Panda, SS; Salman, A; Samir, A; Thomas, SJ | 1 |
Esteve, J; Ivorra, J; Orón, JD; Portilla, J | 1 |
Etienne, D; Fay, M; Forest, N; Gougerot-Pocidalo, MA; Pocidalo, JJ; Roche, Y | 1 |
Blaine, TA; O'Keefe, RJ; Pollice, PF; Puzas, JE; Reynolds, PR; Rosier, RN | 1 |
Chang, WH; Chen, LT; Hong, RC; Lin, FH; Liu, HC; Sun, JS; Tsuang, YH | 1 |
Kraszni, M; Nagy, ZZ; Szentmáry, N | 1 |
Iwagaki, H; Katsuno, G; Mizuno, K; Mori, S; Nishibori, M; Saito, S; Sugita, S; Takahashi, HK; Tanaka, N; Xue, D; Yoshino, T | 1 |
Iwagaki, H; Katsuno, G; Mizuno, K; Mori, S; Nishibori, M; Saito, S; Takahashi, HK; Tanaka, N; Yagi, T; Yoshino, T | 1 |
Iwagaki, H; Katsuno, G; Mori, S; Nishibori, M; Saito, S; Sugita, S; Takahashi, HK; Tanaka, N; Yoshino, T | 1 |
Bhalla, M; Singh, N; Thami, GP | 1 |
Isotalo, T; Kellomäki, M; Kotsar, A; Martikainen, P; Mikkonen, J; Salenius, JP; Talja, M; Tammela, TL; Uurto, I | 1 |
Carmichael, T; Choonara, YE; du Toit, LC; Govender, T; Kumar, P; Pillay, V | 1 |
Adelli, GR; Balguri, SP; Bhagav, P; Janga, KY; Majumdar, S; Tatke, A | 1 |
Li, SY; Liu, K; Xia, Y; Yan, J; Yu, J; Zhang, LT | 1 |
2 review(s) available for ciprofloxacin and indomethacin
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Recently reported biological activities of pyrazole compounds.
Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Pyrazoles | 2017 |
44 other study(ies) available for ciprofloxacin and indomethacin
Article | Year |
---|---|
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Synthesis, antimicrobial and anti-inflammatory activities of some 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 1,2,4-triazolo[3,4-b][1,3,4]thiadiazines bearing trichlorophenyl moiety.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Bacteria; Carrageenan; Edema; Fungi; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Rats; Structure-Activity Relationship; Thiadiazoles | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Synthesis and spectral characterization of a new class of N-(N-methylpiperazinoacetyl)-2,6-diarylpiperidin-4-ones: antimicrobial, analgesic and antipyretic studies.
Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Infective Agents; Bacteria; Drug Evaluation, Preclinical; Fungi; Mice; Microbial Sensitivity Tests; Molecular Structure; Pain; Piperidines; Spectrum Analysis; Structure-Activity Relationship | 2009 |
Synthesis, analgesic, anti-inflammatory and antimicrobial studies of 2,4-dichloro-5-fluorophenyl containing thiazolotriazoles.
Topics: Analgesics; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Microbial Sensitivity Tests; Spectrum Analysis; Structure-Activity Relationship; Thiazoles; Triazoles | 2009 |
New acyclic nucleosides analogues as potential analgesic, anti-inflammatory, anti-oxidant and anti-microbial derived from pyrimido[4,5-b]quinolines.
Topics: Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Bacteria; Carrageenan; Drug Discovery; Edema; Female; Lipid Peroxidation; Male; Mice; Microwaves; Nucleosides; Quinolines; Rats | 2009 |
Design, synthesis and biological investigation of certain pyrazole-3-carboxylic acid derivatives as novel carriers for nitric oxide.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bacteria; Carboxylic Acids; Drug Design; Molecular Structure; Nitric Oxide; Pyrazoles; Rats | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Design, synthesis, antimicrobial, anti-inflammatory and analgesic activity of novel isoxazolyl pyrimido[4,5-b]quinolines and isoxazolyl chromeno[2,3-d]pyrimidin-4-ones.
Topics: Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Bacteria; Behavior, Animal; Chemistry Techniques, Synthetic; Drug Design; Edema; Fungi; Isoxazoles; Microbial Sensitivity Tests; Pyrimidinones; Quinolines; Rats | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Synthesis and pharmacological evaluation of a novel series of 3-aryl-2-(2-substituted-4-methylthiazole-5-yl)thiazolidin-4-one as possible anti-inflammatory and antimicrobial agents.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Bacteria; Bacterial Infections; Carrageenan; Edema; Fungi; Humans; Indomethacin; Microbial Sensitivity Tests; Mycoses; Rats; Thiazoles; Thiazolidines | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Conventional and microwave assisted synthesis of pyrazolone Mannich bases possessing anti-inflammatory, analgesic, ulcerogenic effect and antimicrobial properties.
Topics: Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Bacteria; Carrageenan; Dose-Response Relationship, Drug; Edema; Mice; Microbial Sensitivity Tests; Microwaves; Molecular Structure; Pain; Pyrazolones; Rats; Structure-Activity Relationship | 2014 |
Synthesis and biological evaluation of pyrazolylthiazole carboxylic acids as potent anti-inflammatory-antimicrobial agents.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Carboxylic Acids; Edema; Fungi; Gram-Positive Bacteria; Indomethacin; Microbial Sensitivity Tests; Pyrazoles; Rats; Thiazoles | 2015 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |
Synthesis, pharmacological profile and 2D-QSAR studies of curcumin-amino acid conjugates as potential drug candidates.
Topics: Amino Acids; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Carrageenan; Cell Proliferation; Curcumin; Dose-Response Relationship, Drug; Edema; Mice; Microbial Sensitivity Tests; Molecular Structure; Pain; Pseudomonas aeruginosa; Quantitative Structure-Activity Relationship; Rats; Salmonella typhi; Spleen; Staphylococcus aureus; Streptococcus pyogenes; Ulcer | 2020 |
[Psychotic reaction following administration of indomethacin and ciprofloxacin].
Topics: Ciprofloxacin; Humans; Indomethacin; Male; Middle Aged; Psychoses, Substance-Induced | 1992 |
Comparative effects of quinolones on human mononuclear leucocyte functions.
Topics: Cell Survival; Ciprofloxacin; Humans; Indomethacin; Interleukin-1; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Monocytes; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Modulation of the production of cytokines in titanium-stimulated human peripheral blood monocytes by pharmacological agents. The role of cAMP-mediated signaling mechanisms.
Topics: Bucladesine; Ciprofloxacin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Humans; In Vitro Techniques; Indomethacin; Interleukin-6; Monocytes; Phosphodiesterase Inhibitors; Prostaglandins E; Signal Transduction; Titanium; Tumor Necrosis Factor-alpha | 1997 |
Effect of anti-inflammatory medication on monocyte response to titanium particles.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Ciprofloxacin; Cytokines; Dinoprostone; Enzyme Inhibitors; Humans; Indomethacin; Interleukin-1; Interleukin-6; Materials Testing; Monocytes; Particle Size; Pentoxifylline; Titanium; Tumor Necrosis Factor-alpha | 2000 |
Interaction of indomethacin and ciprofloxacin in the cornea following phototherapeutic keratectomy.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Chemical Precipitation; Ciprofloxacin; Cornea; Drug Interactions; Female; Humans; Hydrogen-Ion Concentration; Indomethacin; Lasers, Excimer; Magnetic Resonance Spectroscopy; Middle Aged; Photorefractive Keratectomy; Wound Healing | 2004 |
Effect of ciprofloxacin-induced prostaglandin E2 on interleukin-18-treated monocytes.
Topics: Anti-Bacterial Agents; Cell Adhesion Molecules; Ciprofloxacin; Cyclooxygenase 1; Cyclooxygenase 2; Cytokines; Dinoprostone; Humans; Indomethacin; Interleukin-18; Leukocytes, Mononuclear; Membrane Proteins; Monocytes; Prostaglandin-Endoperoxide Synthases | 2005 |
The immunosuppressive effects of ciprofloxacin during human mixed lymphocyte reaction.
Topics: B7-1 Antigen; B7-2 Antigen; CD40 Antigens; CD40 Ligand; Cell Proliferation; Ciprofloxacin; Coculture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Immunosuppressive Agents; Indomethacin; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-12; Interleukin-18; Isoquinolines; Leukocytes, Mononuclear; Lymphocyte Culture Test, Mixed; Lymphocytes; Monocytes; Nitrobenzenes; Protein Kinase Inhibitors; Sulfonamides; T-Lymphocytes | 2006 |
The effect of ciprofloxacin on CD14 and toll-like receptor-4 expression on human monocytes.
Topics: Antigens, CD; Ciprofloxacin; Dinoprostone; Humans; In Vitro Techniques; Indomethacin; Intercellular Adhesion Molecule-1; Kinetics; Lipopolysaccharide Receptors; Lipopolysaccharides; Monocytes; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2006 |
Ciprofloxacin-induced erythema nodosum.
Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Erythema Nodosum; Female; Humans; Indomethacin; Treatment Outcome | 2007 |
Urethral in situ biocompatibility of new drug-eluting biodegradable stents: an experimental study in the rabbit.
Topics: Absorbable Implants; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Ciprofloxacin; Dexamethasone; Drug-Eluting Stents; Indomethacin; Lactic Acid; Male; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prosthesis Design; Rabbits; Urethra; Urethral Stricture | 2009 |
In vitro, in vivo, and in silico evaluation of the bioresponsive behavior of an intelligent intraocular implant.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Ciprofloxacin; Computer Simulation; Drug Delivery Systems; Eye; Eye, Artificial; Indomethacin; Inflammation; Polymers; Polysaccharides; Rabbits | 2014 |
Melt-Cast Noninvasive Ocular Inserts for Posterior Segment Drug Delivery.
Topics: Administration, Ophthalmic; Animals; Chemistry, Pharmaceutical; Ciprofloxacin; Drug Delivery Systems; Indomethacin; Male; Ophthalmic Solutions; Polyethylene Glycols; Polymers; Prednisolone; Rabbits; Retina | 2017 |
The combination of ciprofloxacin and indomethacin suppresses the level of inflammatory cytokines secreted by macrophages in vitro.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Ciprofloxacin; Cytokines; Humans; Indomethacin; Inflammation; Interleukin-10; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Tumor Necrosis Factor-alpha | 2022 |