ciprofloxacin and gemfibrozil

ciprofloxacin has been researched along with gemfibrozil in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's3 (25.00)29.6817
2010's7 (58.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cao, CX; Gao, PX; Neu, HC; Rudin, DE; Silverstein, SC1
Breilh, D; Celerier, C; Dorian, M; Grellet, J; Leng, B; Pellegrin, JL; Rispal, P; Saux, MC1
Carryn, S; Seral, C; Tulkens, PM; Van Bambeke, F1
Caceres, NE; Marquez, B; Mingeot-Leclercq, MP; Tulkens, PM; Van Bambeke, F1
Higgins, S; Iftikar, FI; Irshad, A; Jandoc, R; Lee, M; Smith, EM; Wilson, JY1
Brayden, DJ; Hayden, JC; Maher, S; Takyi, J; Wakai, A; Walsh, SJ1

Reviews

1 review(s) available for ciprofloxacin and gemfibrozil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

11 other study(ies) available for ciprofloxacin and gemfibrozil

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Gemfibrozil enhances the listeriacidal effects of fluoroquinolone antibiotics in J774 macrophages.
    The Journal of experimental medicine, 1992, Nov-01, Volume: 176, Issue:5

    Topics: Animals; Cell Line; Ciprofloxacin; Drug Synergism; Gemfibrozil; Listeria monocytogenes; Macrophages; Mice; Norfloxacin

1992
Comparative uptake of sparfloxacin and ciprofloxacin into human THP 1 monocytic cells.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:3

    Topics: Anti-Infective Agents; Cell Line; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Gemfibrozil; Humans; Hydrogen-Ion Concentration; Hypolipidemic Agents; Monocytes; Quinolones

1996
Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus.
    The Journal of antimicrobial chemotherapy, 2003, Volume: 51, Issue:5

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azithromycin; Ciprofloxacin; Gemfibrozil; Humans; In Vitro Techniques; Listeriosis; Macrophages; Staphylococcal Infections; Subcellular Fractions; Verapamil

2003
Identification of the efflux transporter of the fluoroquinolone antibiotic ciprofloxacin in murine macrophages: studies with ciprofloxacin-resistant cells.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Acridines; Animals; Anti-Infective Agents; Blotting, Western; Cell Line; Chemokines, CC; Ciprofloxacin; Gemfibrozil; Gene Silencing; Macrophage Inflammatory Proteins; Macrophages; Mice; Multidrug Resistance-Associated Proteins; RNA, Messenger; Tetrahydroisoquinolines

2009
In vitro inhibition of cytochrome P450-mediated reactions by gemfibrozil, erythromycin, ciprofloxacin and fluoxetine in fish liver microsomes.
    Aquatic toxicology (Amsterdam, Netherlands), 2012, Volume: 109

    Topics: Animals; Ciprofloxacin; Cytochrome P-450 Enzyme System; Enzyme Activation; Erythromycin; Fish Proteins; Fluoxetine; Gemfibrozil; Microsomes, Liver; Oncorhynchus mykiss; Water Pollutants, Chemical; Zebrafish

2012
Effect of Overencapsulation on the Disintegration and Dissolution of Licensed Formulations for Blinding in Randomized Controlled Trials.
    Journal of pharmaceutical sciences, 2019, Volume: 108, Issue:3

    Topics: Chemistry, Pharmaceutical; Ciprofloxacin; Drug Compounding; Drug Liberation; Excipients; Furosemide; Gemfibrozil; Penicillin V; Randomized Controlled Trials as Topic; Solubility; Tablets

2019