ciprofloxacin and gatifloxacin

ciprofloxacin has been researched along with gatifloxacin in 219 studies

Research

Studies (219)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (4.57)18.2507
2000's156 (71.23)29.6817
2010's46 (21.00)24.3611
2020's7 (3.20)2.80

Authors

AuthorsStudies
Cohen, MA; Domagala, JM; Gogliotti, RD; Gracheck, SJ; Huband, MD; Sanchez, JP; Sesnie, JA; Shapiro, MA1
García-March, FJ; Jaén-Oltra, J; Pérez-Giménez, F; Salabert-Salvador, MT; Tomás-Vert, F1
Inagaki, H; Kawakami, K; Kawato, HC; Matsuhashi, N; Miyauchi, RN; Miyauchi, S; Ohki, H; Takahashi, H; Takemura, M1
Keserü, GM1
Almstead, JI; Gray, JL; Hu, XE; Kim, NK; Ledoussal, B; Seibel, WL1
Nagashima, R; Nishikawa, T; Tobita, M1
Appelbaum, PC; Bhawsar, SB; Bozdogan, B; de Souza, NJ; Desai, VN; Deshpande, PK; Gupte, SV; Hooper, DC; Jacobs, MR; Jha, R; Khorakiwala, HF; Patel, MV; Shetty, N; Shukla, MC; Strahilevitz, J; Yeole, RD1
Bradbury, BJ; Cheng, J; Deshpande, M; Hashimoto, A; Lucien, E; Marlor, CW; Ou, Y; Podos, SD; Pucci, MJ; Song, Y; Thanassi, JA; Thoma, CL; Wang, Q; Wiles, JA1
Chen, S; Cui, S; McDermott, PF; Meng, J; Paulsen, I; White, DG; Zhao, S1
Bronstein, JC; Domagala, JM; Dunham, SA; Ellsworth, EL; Gage, JW; Gracheck, SJ; Hanna, DL; Huband, MD; Joannides, ET; Liu, JY; Nguyen, DQ; Sanchez, JP; Shapiro, MA; Showalter, HD; Singh, R; Stier, MA; Tran, TP; Watson, BM1
Klugman, KP; Levin, BR; McGee, L; Rozen, DE1
Hashimoto, K; Hayashi, K; Ikee, Y; Nagao, Y; Nakashima, M; Sano, S; Shiro, M1
Barth, AL; Castanheira, M; Gales, AC; Nicoletti, AG; Pereira, AS; Pignatari, AC1
Cohen, MA; Ellsworth, E; Gage, JW; Gibson, GW; Gracheck, SJ; Hanna, DL; Huband, MD; Skerlos, LA; Stier, MA; Sulavik, MC; Zurack, M1
Jain, M; Jayadev, S; Mishra, B; Patel, PR; Solanki, M; Soni, R; Srivastava, BK; Valani, D1
Aubry, A; Cambau, E; Jarlier, V; Matrat, S; Petrella, S; Sougakoff, W1
Clark, KP; Griffith, ME; Hawley, JS; Hospenthal, DR; Johnson, EN; Moon, JE; Murray, CK1
Courvalin, P; Galimand, M; Périchon, B1
Castanheira, M; Jones, RN; Mendes, RE; Sader, HS; Toleman, MA; Walsh, TR1
Arakawa, Y; Kato, H; Kimura, K; Konda, T; Shibata, N; Shibayama, K; Suzuki, S; Wachino, J; Yamane, K1
Adams, DA; Donskey, CJ; Riggs, MM1
Morgan-Linnell, SK; Zechiedrich, L1
Acosta, CJ; Agtini, M; Albert, MJ; Anh, DD; Arjyal, A; Basnyat, B; Bhattacharya, SK; Bhutta, ZA; Campbell, JI; Canh, DG; Chau, TT; Chinh, NT; Clemens, JD; Diep, TS; Dolecek, C; Dong, B; Dougan, G; Dutta, S; Farrar, J; Galindo, CM; Hien, TT; Honghui, Y; La, TT; Naheed, A; Newton, PN; Nga, TT; Ochiai, RL; Page, AL; Parry, CM; Phetsouvanh, R; Phuong, LT; Rang, NN; Schultsz, C; Tuan, PQ; Van Be Bay, P; Van Minh Hoang, N; Van Vinh Chau, N; Vinh, H; von Seidlein, L; Wain, J1
Andres, P; Centrón, D; Galas, M; Guerriero, L; Petroni, A; Quiroga, C; Quiroga, MP; Soler Bistué, AJ; Tokumoto, M; Tolmasky, ME; Vargas, LJ; Zorreguieta, A1
Appelbaum, PC; Bogdanovich, T; Clark, C; Dewasse, B; Ednie, L; McGhee, P; Smith, K1
China, A; Dinakaran, M; Nagaraja, V; Senthilkumar, P; Sriram, D; Yogeeswari, P1
Bitting, C; Gruppo, V; Johnson, CM; Lenaerts, AJ; Marietta, KS; Orme, IM; Woolhiser, L1
Ho, YR; Hung, KH; Janapatla, RP; Wu, CW; Wu, HM; Wu, JJ; Yan, JJ1
Lombardo, F; Obach, RS; Waters, NJ1
Bonventre, EJ; Doyle, TB; Du, Q; Duncan, L; Lynch, AS; Morris, TW; Robertson, GT; Roche, ED; Yan, D1
Jia, L; Sun, H1
Béliveau, C; Labbé, AC; Laverdière, M; Louie, T; Maccannell, D; Pépin, J; Poirier, L; Savoie, M1
Cattoir, V; Nordmann, P; Poirel, L1
Hiramatsu, K; Kikuchi, K; Ohtsuka, M; Ono, Y; Sasaki, T; Shimizu, K; Takahashi, N2
Arhin, FF; Caron, L; Delorme, D; Dietrich, E; Fadhil, I; Ferreira, SS; Houghton, TJ; Kang, T; Laquerre, K; Lehoux, D; Liu, J; Moeck, G; Ostiguy, V; Parr, TR; Poirier, H; Rafai Far, A; Sarmiento, I; Tanaka, KS; Viens, F1
Arhin, FF; Delorme, D; Dietrich, E; Fadhil, I; Far, AR; Ferreira, SS; Houghton, TJ; Kang, T; Lafontaine, Y; Laquerre, K; Lehoux, D; Liu, J; Moeck, G; Ostiguy, V; Parr, TR; Poirier, H; Sarmiento, I; Tanaka, KS; Viens, F1
Becnel Boyd, L; Morgan-Linnell, SK; Steffen, D; Zechiedrich, L1
Becnel Boyd, L; Hamill, RJ; Horton, LB; Jimenez, JR; Maynard, MJ; Morgan-Linnell, SK; Steffen, D; Sucgang, R; Versalovic, J; Zechiedrich, L1
Appelbaum, PC; Ednie, LM; Kosowska-Shick, K; McGhee, P1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Hirakata, Y; Imamura, Y; Izumikawa, K; Kakeya, H; Kamihira, S; Kohno, S; Seki, M; Sugahara, K; Yamamoto, K; Yamamoto, Y; Yanagihara, K1
Brunner, LS; Haas, W; Lee, JC; Morris, TW; Pillar, CM; Zurenko, GE1
Chhasatia, MR; Gandhi, DS; Patel, MN1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Azéma, J; Dewelle, J; Guidetti, B; Kiss, R; Korolyov, A; Le Calve, B; Malet-Martino, M; Martino, R; Mijatovic, T; Vaysse, J1
Inagaki, H; Ito, M; Kawakami, K; Matsuhashi, N; Miyauchi, R; Ohki, H; Takahashi, H; Takemura, M1
Ekambaram, R; Raghunathan, M; Raghunathan, R; Rao, SS1
Hamasuna, R; Jensen, JS; Osada, Y1
Martínez, JL; Sánchez, MB1
Anquetin, G; Biot, C; Dive, D; Dubar, F; Khalife, J; Pradines, B1
Avdeef, A; Sun, N; Tam, KY; Tsinman, O1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Barber, M; Eberly, LE; Feeney, LA; Miller, GH; Summers, A; Wortmann, G; Zapor, MJ1
Sen, S; Sinha, N1
Anquetin, G; Aubry, A; Capton, E; Gomez, C; Jarlier, V; Lamouri, A; Pantel, A; Ponien, P; Serradji, N1
Imai, YN; Oiki, S; Ryu, S1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Lynch, AS; Ma, Z1
Brozovic, A; Dowson, CG; Gazvoda, M; Košmrlj, J; Lloyd, A; Osmak, M; Proud, C; Roper, DI; Vajs, J1
Feng, LS; Liu, X; Pan, B; Zhang, GF; Zhang, S1
Cheng, XW; Fan, YL; Feng, LS; Wu, JB; Zhang, FZ1
Liu, ML; Liu, X; Pan, B; Zhang, GF; Zhang, S1
Bai, L; Deng, JL; Gao, F; Lv, ZS; Wang, Y; Xu, Z; Zhang, F; Zhao, SJ1
Ba, Y; Hou, X; Wang, S; Xu, Z; Yang, H; Zhang, J1
Ciura, K; Fallarero, A; Fedorowicz, J; Gilbert-Girard, S; Konopacka, A; Lejnowski, D; Morawska, M; Sączewski, J; Savijoki, K; Skok, Ž; Tomašič, T; Waleron, K1
Blaskovich, MAT; Pham, TDM; Ziora, ZM1
Dana, S; Dhar, SK; Gurung, SK; Kumar, S; Mondal, N; Mukhopadhyay, P; Valissery, P1
Brady, SF; Koirala, B; Peek, J1
Bhagwat, S; Bhawsar, S; Deshpande, P; Joshi, S; Patel, M; Yeole, R1
Aoyama, H; Fukuda, H; Hirai, K; Hosaka, M; Tomizawa, H; Yasue, T1
Chida, K; Hayakawa, H; Iwata, M; Kitazawa, H; Sato, A1
Andrews, JM; Boswell, F; Brenwald, NP; Wise, R1
Bauernfeind, A1
Beach, ML; Doern, GV; Jones, RN; Pfaller, MA1
Dubois, J; St-Pierre, C1
Appelbaum, PC; Hoellman, DB; Jacobs, MR; Lin, G1
Brisse, S; Fluit, AC; Köhrer, K; Martin, N; Milatovic, D; Scheuring, S; Schmitz, FJ; Verhoef, J1
Losnedahl, KJ; Pendland, SL; Schriever, CA1
Hershberger, E; Rybak, MJ1
Firsov, AA; Kononenko, OV; Lubenko, IY; Vostrov, SN; Zinner, SH1
Berger, S; Gajjar, DA; Grasela, DM; Kollia, GD; LaCreta, FP; Smith, WB; Stolz, RR; Swingle, M1
Edmond, M; Heinemann, B; Seifert, H; Wisplinghoff, H1
Hollauer, K; Kirchbauer, D; Naber, KG; Witte, W1
Bonner, D; Conetta, B; Fung-Tomc, J; Huczko, E; Macko, A; Stickle, T; Valera, L1
Bonner, DP; Fung-Tomc, J; Gradelski, E; Kolek, B; Minassian, B; Valera, L1
Bartlett, MG; Stewart, JT; Vishwanathan, K1
Jones, RN; Pfaller, MA1
Biedenbach, DJ; Jones, RN; Pfaller, MA1
Bonner, DP; Fung-Tomc, J; Gradelski, E; Huczko, E; Minassian, B1
Boos, M; Fluit, AC; Hafner, D; Jagusch, H; Mayer, S; Schmitz, FJ; Verhoef, J1
Appelbaum, PC; Davies, TA; Dewasse, BE; Jacobs, MR; Nagai, K1
Hooper, DC; Ince, D1
Firsov, AA; Gilbert, D; Lubenko, IY; Simmons, K; Zinner, SH1
Andriole, VT; Bassetti, M; Callan, DA; Dembry, LM; Farrel, PA1
Beach, ML; Jones, RN; Pfaller, MA1
Frothingham, R2
Calvo, A; García, R; Gómez-Lus, ML; Leturia, A; Sevillano, D; Valero, E1
Kirstein, JM; Mathew, CP; Orchard, D; Richard, GA; Yang, JY1
Auerbach, SM; Brown, GL; Cox, CE; Fox, BC; Marbury, TC; Pittman, WG; Yang, JY1
Karenchak, LM; Kowalski, RP; Mather, R; Romanowski, EG1
Bosso, JA; Enzweiler, KA; Friedrich, LV; Hoban, D; Wagner, D; White, RL1
Schaeffer, AJ1
Brown-Elliott, BA; Crist, CJ; Mann, L; Wallace, RJ; Wilson, RW1
Garey, KW; Jung, R; Neuhauser, MM; Pendland, SL; Prause, JL1
Cheong, HJ; Choo, YS; Kang, MW; Kim, WJ; Kim, YS; Lee, KW; Park, YJ; Woo, JH; Yong, DE1
Araake, M; Hara, T; Nishino, T; Watabe, H1
Araake, M; Hara, T; Nishino, T; Shimizu, M; Tabata, M; Watabe, H1
Hasegawa, M; Kobayashi, I; Matsuzaki, K; Sato, Y; Shikano, M; Watabe, E; Yoshimori, K1
Araake, M; Maebashi, K; Tani, M; Watabe, H1
Bello, S; Torres, A1
Chiang, SR; Chuang, YC; Ko, WC; Lee, HC; Tang, HJ; Wang, YY1
Carpenter, TR; Kaufman, MB; McDonnell, PJ; Sarayba, MA; Sweet, PM; Taban, M; Tungsiripat, T1
Doganay, M; Esel, D; Sumerkan, B1
Piddock, L; Ricci, V1
Dhaliwal, DK; Gordon, YJ; Karenchak, LM; Kowalski, RP; Mah, FS; Ritterband, DC; Romanowski, EG1
Ebisu, H; Fukuda, H; Kishii, R; Takei, M1
Almaraz, F; Baquero, F; Cantón, R; Jones, RN; Loza, E; Martín, R; Morosini, MI; Pascual, A; Perea, E; Tubau, F1
Leggett, J; Saravolatz, LD1
Fukuda, Y; Hirakata, Y; Kadota, J; Kohno, S; Miyazaki, Y; Murata, I; Otsu, Y; Tashiro, T; Tomono, K; Tsukamoto, K; Yanagihara, K1
Hong, JW; Hu, CQ; Sheng, LS1
Choo, CM; Lim, T; Lim, YS; Ngan, CC; Toh, GL1
Ankel-Fuchs, D; Boy, D; Kinzig-Schippers, M; Naber, KG; Sörgel, F; Well, M1
Ankel-Fuchs, D; Bartnicki, A; Bischoff, W; Hanus, M; Milutinovic, S; Naber, KG; Schönwald, S; van Belle, F; Weitz, P1
Acharya, B; Arakawa, S; Gotoh, A; Hinata, N; Kamidono, S; Kawabata, M; Kinoshita, S; Kofuku, T; Okada, H; Shigemura, K; Shirakawa, T1
Brooks, TJ; Lever, MS; Sefton, AM; Simpson, AJ; Steward, J1
Guo, HY; Liu, ML; Qi, JJ; Sun, LY1
Allin, DM; Ankel-Fuchs, D; Clarysse, L; Haworth, DA; Hopkins, G; James, IG; Naber, KG; Raini, C; Schneider, H; Wall, A; Weitz, P1
Fukuda, Y; Hirakata, Y; Kadota, J; Kohno, S; Miyazaki, Y; Murata, I; Tashiro, T; Tomono, K; Tsukamoto, K; Yanagihara, K1
Dick, JD; Hose, S; Hyon, JY; Joo, MJ; O'Brien, TP; Sinha, D1
Beedham, RJ; Brooks, TJ; Lever, MS; Russell, P; Stagg, AJ; Steward, J; Taylor, RR1
Burgess, DS; Frei, CR; Moczygemba, LR1
Evangelista, AT; Jones, ME; Karlowsky, JA; Sahm, DF; Thornsberry, C; Yee, YC1
Carrier, M; Jensen, H; Short, B; Zerouala, C1
Brooks, TJ; Lever, MS; Nelson, M; Piercy, T; Simpson, AJ; Steward, J1
Bloom, A; Donnenfeld, ED; Nedrud, C; Perry, HD; Snyder, RW; Solomon, R; Stein, J1
Miller, J1
Paramasivan, CN; Rahman, F; Sulochana, S1
Ashcraft, DS; Pankey, GA1
Graff, JM; Kesler-Diaz, A; McDonnell, PJ; Osann, KE; Reiser, BJ; Sarayba, MA; Shamie, N; Sweet, PM; Taban, M1
Abelson, MB; Shapiro, A; Torkildsen, G; Wagner, RS1
Kenton, I; McKinnon, PS; Mohr, JF; Okhuysen, PC; Peymann, PJ; Septimus, E1
Brooks, TJ; Lever, MS; Piercy, T; Steward, J1
Horii, T; Monji, A; Nagura, O; Uemura, K1
Al-Dgither, S; Alvi, SN; Hammami, MM1
Garrison, MW1
Donnenfeld, ED; Donnenfeld, RS; Jensen, HG; Perry, HD; Snyder, RW; Solomon, R; Stein, J; Wittpenn, JR1
Fukuda, H; Hayashi, K; Kadowaki, SE; Takei, M1
Jesudasan, CA; Kalavathy, CM; Kaliamurthy, J; Parmar, P; Prasanth, DA; Salman, A; Thomas, PA1
Anguita-Alonso, P; Jacofsky, DJ; Osmon, DR; Patel, R; Piper, KE; Rouse, MS1
Brooks, TJ; Lever, MS; Piercy, T; Simpson, AJ; Steward, J1
Arpin, C; Ba, BB; Chausse, A; Quentin, C; Saux, MC; Vidaillac, C1
Appelbaum, PC; Bozdogan, B; Choi, DR; Credito, K; Dewasse, B; Kosowska-Shick, K; Lin, G; McGhee, P; Pankuch, GA; Ryu, JM1
Bosso, JA; Mauldin, PD1
Black, JA; Moland, ES; Thomson, KS; Wickman, PA1
Eiland, E; Hassoun, A1
Aydemir, S; Cilli, F; Tunger, A1
Garg, RK; Marak, RS; Ray, P; Sharma, J1
Amarnath, SK; Joshi, S1
Black, JA; Hanson, ND; Smith Moland, E; Thomson, KS; Wickman, PA1
Adam, HJ; Baudry, TJ; Hoban, CJ; Hoban, DJ; Laing, NM; Nichol, KA; Schurek, KN; Zhanel, GG1
Fiscella, RG; Jensen, MK1
Rodríguez, JC; Royo, G; Ruiz, M; Sirvent, E1
Harish, BN; Menezes, GA; Parija, SC; Sarangapani, K1
D'Azevedo, PA; Francisco, W; Oliveira, AD1
Miyata, K; Ohtani, H; Sawada, Y; Tsujimoto, M1
Amyes, SG; Dobay, O; Ghidán, A; Matuz, M; Nagy, K; Rozgonyi, F1
Catero, M1
Blondeau, JM; Borsos, S; Hesje, CK1
Blondeau, JM; Hedlin, P1
Gordon, YJ; Kowalski, RP; Mah, FS; Romanowski, EG; Yates, KA1
Asari, M; Hirano, T; Iseki, K; Itagaki, S; Kobayashi, M; Osaka, Y; Yasuda, S1
Bezwada, P; Clark, LA; Schneider, S1
Arias, CA; Cárdenas, AM; Castañeda, E; Díaz, L; Díaz, PL; Hidalgo, M; Reyes, J; Rincón, S; Vanegas, N1
Fiscella, RG; Jensen, MK; Mooney, B; Moshirfar, M1
Asbell, PA; Epstein, SP; Sosa, AB1
Bai, XQ; Deng, SJ; Li, L; Li, R; Liang, QF; Luo, SY; Sun, XG; Wang, ZQ1
Horstkotte, MA; Knobloch, JK; Mack, D; Rohde, H; Von Osten, H1
Bosgelmez-Tinaz, G; Coskun-Ari, FF1
Qi, HM; Wei, MJ; Zhang, L; Zhao, CY1
Choi, JS; Joo, CK; Kim, KA; Lim, JA; Park, SH1
Holland, EJ; Lane, SS; Lindstrom, RL1
McCulley, JP1
Alam, MR; Garg, P; Gopinathan, U; Krishnaiah, S; Reddy, AK; Sharma, S1
Conway, J; Hutson, P; Leiferman, EM; Noonan, KJ; Sansone, JM; Wilsman, NJ1
Kim, J; Ohtani, H; Sawada, Y; Tsujimoto, M1
Chen, WL; Hu, FR; Tsai, TH1
Anupama, M; Murthy, PB; Seiler, JP1
Araújo, DP; de Almeida, MV; de Carvalho, GS; de Souza, MV; Saraiva, MF; Tran Huu Dau, ME1
Chang, CL; Choi, GE; Kang, JE; Kim, JM; Kim, KH; Lee, EY; Tateda, K; Yamaguchi, K1
Banaszkiewicz, A; Młynarczyk, G; Obuch-Woszczatyński, P; Pituch, H; Radzikowski, A; Wultańska, D1
Acharya, NR; Cevallos, V; Fintelmann, RE; Gaynor, BD; Hoskins, EN; Keenan, JD; Lietman, TM1
Ambrose, PG; Bhavnani, SM; Caws, M; Chau, TT; Dung, NT; Farrar, J; Hammel, JP; Hien, TT; Kulawy, R; Mai, PP; Reynolds, DK; Thwaites, GE; Török, ME; Van Wart, SA1
Green, K; Low, DE; McGeer, A; Melano, R; Patel, SN; Pillai, DR; Tyrrell, GJ1
Anh, ND; Anh, VT; Baker, S; Bay, PV; Campbell, JI; Chau, NV; Chinh, MT; Day, JN; Diep, TS; Dolecek, C; Duy, PT; Farrar, JJ; Hoang, NV; Lan, NP; Loan, HT; Minh, PV; Mong, BL; Nga, TV; Nhu, NT; Phuong, le T; Tham, NT; Thao, NT; Thuy, CT; Vinh, H; Wolbers, M1
Galvis, V; Rey, JJ; Tello, A; Villareal, D; Wong, CA1
Chavda, K; Drlica, K; Hussain, S; Kerns, RJ; Kreiswirth, BN; Kurepina, N; Malik, M; Shah, N; Zhao, X1
Liu, M; Xia, Q; Yang, Y1
Kim, JN; Park, M; Rafii, F; Sutherland, JB1
Bian, A; Blackman, A; Eden, S; Maruri, F; Mitchel, E; Shintani, AK; Sterling, TR; van der Heijden, YF; Warkentin, JV1
Kalavathy, CM; Kaliamurthy, J; Nelson Jesudasan, CA; Parmar, P; Thomas, PA1
Ai, NT; Baker, S; Campbell, JI; Dong, N; Dougan, G; Dung, TT; Farrar, JJ; Hien, TT; Hoang, NV; Holt, KE; Kim, DW; Lien, NT; Minh, PV; Nga, TT; Nhu, NT; Parkhill, J; Parry, CM; Phu, BD; Phuc, HL; Thanh, DP; Thieu Nga, TV; Thompson, C; Thomson, NR; Thuy, CT; Tien, NM; Tuyet, PT; Vinh, H; Vinh, NT; Vinh, PV; Vu Tra, MP1
Ghaly, H; Jörns, A; Rustenbeck, I1
Betlejewska-Kielak, K; Biernacka, J; Grudzień, M; Kłosińska-Szmurło, E; Mazurek, AP; Pluciński, FA1
Wu, L; Wu, X1
Baker-Austin, C; Fletcher, DE; McArthur, JV; Tuckfield, RC1
Arjyal, A; Baker, S; Basnyat, B; Dolecek, C; Dongol, S; Dougan, G; Gajurel, D; Ha Thanh, T; Ho Thi, N; Holt, KE; Karkey, A; Parry, CM; Pham Thanh, D; Pickard, D; Pradhan, A; Rabaa, MA; Shrestha, SK; Thompson, CN; Thwaites, GE; Tran Vu Thieu, N; Voong Vinh, P; Wolbers, M; Wong, V1
Hsu, MC; Leunk, R; Makin, K; Roychoudhury, S; Twinem, T1
Chaiprasert, A; Disratthakit, A; Doi, N; Leechawengwongs, M; Prammananan, T; Thaipisuttikul, I; Tribuddharat, C1
Abdelbacki, AMM; El-Gebaly, RH; Fadel, MA; Mohamed, SA1
Balaji, V; Bandyopadhyay, R; Jasmine, S; Rupali, P; Sathyendra, S; Yadav, B1
Lan, R; Shen, R; Xia, Z; Yu, R; Yu, Y; Yuan, Z1
Das, S; Gunasekaran, R; Mitra, S; Mohamed, A; Prajna, L; Prajna, NV; Sharma, S; Soni, T1
Ebrahimzadeh, F; Gholami, S; Jafari-Sales, A; Rostami, A; Zadeh, FA1
Bykov, K; Fischer, MA; Gagne, JJ; Kattinakere-Sreedhara, S; Wang, J1
Agrawal, D; Chatterjee, S; Gangwe, AB; Gomase, SN; Mishra, M; Parchand, SM1

Reviews

9 review(s) available for ciprofloxacin and gatifloxacin

ArticleYear
4-Quinolone derivatives and their activities against Gram positive pathogens.
    European journal of medicinal chemistry, 2018, Jan-01, Volume: 143

    Topics: 4-Quinolones; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2018
Fluoroquinolone derivatives and their anti-tubercular activities.
    European journal of medicinal chemistry, 2018, Feb-25, Volume: 146

    Topics: Animals; Antitubercular Agents; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis

2018
Ciprofloxacin derivatives and their antibacterial activities.
    European journal of medicinal chemistry, 2018, Feb-25, Volume: 146

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Gram-Positive Bacteria; Molecular Structure; Structure-Activity Relationship

2018
Fluoroquinolone-isatin hybrids and their biological activities.
    European journal of medicinal chemistry, 2019, Jan-15, Volume: 162

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Antitubercular Agents; Antiviral Agents; Fluoroquinolones; Humans; Isatin; Structure-Activity Relationship

2019
Nitroimidazole-containing compounds and their antibacterial and antitubercular activities.
    European journal of medicinal chemistry, 2019, Oct-01, Volume: 179

    Topics: Anti-Bacterial Agents; Bacterial Infections; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Nitroimidazoles

2019
Quinolone antibiotics.
    MedChemComm, 2019, Oct-01, Volume: 10, Issue:10

    Topics:

2019
The expanding role of fluoroquinolones.
    The American journal of medicine, 2002, Jul-08, Volume: 113 Suppl 1A

    Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Urinary Tract Infections

2002
Dysglycemia and fluoroquinolones: are you putting patients at risk?
    The Journal of family practice, 2007, Volume: 56, Issue:2

    Topics: Adolescent; Adult; Aza Compounds; Bacterial Infections; Blood Glucose; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Approval; Evidence-Based Medicine; Family Practice; Female; Fluoroquinolones; Gatifloxacin; Humans; Hyperglycemia; Hypoglycemia; Incidence; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Randomized Controlled Trials as Topic; Risk Assessment; United States; United States Food and Drug Administration

2007
Globally Vibrio cholera antibiotics resistance to RNA and DNA effective antibiotics: A systematic review and meta-analysis.
    Microbial pathogenesis, 2022, Volume: 172

    Topics: Anti-Bacterial Agents; Cephalothin; Cholera; Cholera Toxin; Ciprofloxacin; Drug Resistance, Bacterial; Furazolidone; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Nalidixic Acid; Nitrofurantoin; Norfloxacin; Novobiocin; Rifampin; Vibrio cholerae; Virulence Factors

2022

Trials

11 trial(s) available for ciprofloxacin and gatifloxacin

ArticleYear
Effect of multiple-dose gatifloxacin or ciprofloxacin on glucose homeostasis and insulin production in patients with noninsulin-dependent diabetes mellitus maintained with diet and exercise.
    Pharmacotherapy, 2000, Volume: 20, Issue:6 Pt 2

    Topics: Adult; Anti-Infective Agents; Blood Glucose; Ciprofloxacin; Diabetes Mellitus, Type 2; Double-Blind Method; Exercise; Female; Fluoroquinolones; Gatifloxacin; Glucose Tolerance Test; Humans; Insulin; Islets of Langerhans; Male; Middle Aged

2000
Single-dose fluoroquinolone therapy of acute uncomplicated urinary tract infection in women: results from a randomized, double-blind, multicenter trial comparing single-dose to 3-day fluoroquinolone regimens.
    Urology, 2002, Volume: 59, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Middle Aged; Recurrence; Treatment Outcome; Urinary Tract Infections

2002
A randomized, double-blind, multicenter comparison of gatifloxacin versus ciprofloxacin in the treatment of complicated urinary tract infection and pyelonephritis.
    Clinical therapeutics, 2002, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Female; Fluoroquinolones; Gatifloxacin; Humans; Male; Middle Aged; Pyelonephritis; Urinary Tract Infections

2002
Urinary bactericidal activity, urinary excretion and plasma concentrations of gatifloxacin (400 mg) versus ciprofloxacin (500 mg) in healthy volunteers after a single oral dose.
    International journal of antimicrobial agents, 2004, Volume: 23 Suppl 1

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Cross-Over Studies; Female; Fluoroquinolones; Gatifloxacin; Humans; Kinetics; Male; Metabolic Clearance Rate; Microbial Sensitivity Tests; Reference Values

2004
Gatifloxacin 200 mg or 400 mg once daily is as effective as ciprofloxacin 500 mg twice daily for the treatment of patients with acute pyelonephritis or complicated urinary tract infections.
    International journal of antimicrobial agents, 2004, Volume: 23 Suppl 1

    Topics: Bacterial Infections; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluoroquinolones; Gatifloxacin; Humans; Male; Middle Aged; Pyelonephritis; Treatment Outcome; Urinary Tract Infections

2004
Gatifloxacin 400 mg as a single shot or 200 mg once daily for 3 days is as effective as ciprofloxacin 250 mg twice daily for the treatment of patients with uncomplicated urinary tract infections.
    International journal of antimicrobial agents, 2004, Volume: 23, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Double-Blind Method; Female; Fluoroquinolones; Gatifloxacin; Humans; Male; Middle Aged; Treatment Outcome; Urinary Tract Infections; Urine

2004
Penetration of topically applied gatifloxacin 0.3%, moxifloxacin 0.5%, and ciprofloxacin 0.3% into the aqueous humor.
    Ophthalmology, 2005, Volume: 112, Issue:3

    Topics: Aged; Anti-Infective Agents; Aqueous Humor; Aza Compounds; Biological Availability; Cataract Extraction; Chromatography, High Pressure Liquid; Ciprofloxacin; Double-Blind Method; Female; Fluoroquinolones; Gatifloxacin; Humans; Male; Middle Aged; Moxifloxacin; Ophthalmic Solutions; Prospective Studies; Quinolines

2005
Comparison of topical gatifloxacin 0.3% and ciprofloxacin 0.3% for the treatment of bacterial keratitis.
    American journal of ophthalmology, 2006, Volume: 141, Issue:2

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Bacteria; Child; Ciprofloxacin; Corneal Ulcer; Double-Blind Method; Eye Infections, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Humans; Male; Microbial Sensitivity Tests; Microbiological Techniques; Middle Aged; Ophthalmic Solutions; Prospective Studies

2006
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Injections, Intramuscular; Isoniazid; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal; Young Adult

2011
A multi-center randomized trial to assess the efficacy of gatifloxacin versus ciprofloxacin for the treatment of shigellosis in Vietnamese children.
    PLoS neglected tropical diseases, 2011, Volume: 5, Issue:8

    Topics: Anti-Bacterial Agents; Child, Preschool; Ciprofloxacin; Dysentery, Bacillary; Feces; Female; Fluoroquinolones; Gatifloxacin; Hospitals; Humans; Hyperglycemia; Hypoglycemia; Infant; Male; Proportional Hazards Models; Shigella; Treatment Outcome; Vietnam

2011
A novel ciprofloxacin-resistant subclade of H58 Salmonella Typhi is associated with fluoroquinolone treatment failure.
    eLife, 2016, Mar-11, Volume: 5

    Topics: Anti-Bacterial Agents; Bacterial Typing Techniques; Ceftriaxone; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Genotype; Humans; Nepal; Salmonella typhi; Sequence Analysis, DNA; Treatment Failure; Typhoid Fever

2016

Other Studies

199 other study(ies) available for ciprofloxacin and gatifloxacin

ArticleYear
The synthesis, structure-activity, and structure-side effect relationships of a series of 8-alkoxy- and 5-amino-8-alkoxyquinolone antibacterial agents.
    Journal of medicinal chemistry, 1995, Oct-27, Volume: 38, Issue:22

    Topics: Animals; Anti-Bacterial Agents; Bacteria; CHO Cells; Cricetinae; Dermatitis, Phototoxic; Drug Design; Female; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Quinolones; Structure-Activity Relationship

1995
Artificial neural network applied to prediction of fluorquinolone antibacterial activity by topological methods.
    Journal of medicinal chemistry, 2000, Mar-23, Volume: 43, Issue:6

    Topics: Algorithms; Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Neural Networks, Computer; Structure-Activity Relationship

2000
Synthesis and structure-activity relationships of 5-amino-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-8-methylquinolonecarboxylic acid antibacterials having fluorinated 7-[(3R)-3-(1-aminocyclopropan-1-yl)pyrrolidin-1-yl] substituents.
    Journal of medicinal chemistry, 2003, Mar-13, Volume: 46, Issue:6

    Topics: Anti-Bacterial Agents; Cyclopropanes; Drug Resistance, Bacterial; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quinolones; Stereoisomerism; Structure-Activity Relationship

2003
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
Discovery of (3S)-amino-(4R)-ethylpiperidinyl quinolones as potent antibacterial agents with a broad spectrum of activity and activity against resistant pathogens.
    Journal of medicinal chemistry, 2003, Aug-14, Volume: 46, Issue:17

    Topics: Anti-Bacterial Agents; Bacteria; DNA Gyrase; DNA, Superhelical; Drug Resistance, Bacterial; Escherichia coli; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Piperidines; Quinolones; Stereoisomerism; Structure-Activity Relationship

2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
A chiral benzoquinolizine-2-carboxylic acid arginine salt active against vancomycin-resistant Staphylococcus aureus.
    Journal of medicinal chemistry, 2005, Aug-11, Volume: 48, Issue:16

    Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Clinical Trials, Phase I as Topic; Dogs; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Half-Life; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Mutation; Prodrugs; Quinolizines; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship; Vancomycin Resistance

2005
Isothiazoloquinolones containing functionalized aromatic hydrocarbons at the 7-position: synthesis and in vitro activity of a series of potent antibacterial agents with diminished cytotoxicity in human cells.
    Bioorganic & medicinal chemistry letters, 2006, Mar-01, Volume: 16, Issue:5

    Topics: Anti-Bacterial Agents; Azo Compounds; Cell Line; Escherichia coli; Humans; Hydrocarbons, Aromatic; Microbial Sensitivity Tests; Molecular Structure; Quinolines; Staphylococcus aureus; Sulfhydryl Compounds

2006
Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2

    Topics: Animals; Anti-Infective Agents; DNA Topoisomerases; Drug Resistance, Bacterial; Fluoroquinolones; Gene Targeting; Genes, Bacterial; Mutation; Salmonella Infections, Animal; Salmonella typhimurium

2007
3-aminoquinazolinediones as a new class of antibacterial agents demonstrating excellent antibacterial activity against wild-type and multidrug resistant organisms.
    Journal of medicinal chemistry, 2006, Nov-02, Volume: 49, Issue:22

    Topics: Anti-Bacterial Agents; Bacteria; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Positive Bacteria; Methicillin Resistance; Microbial Sensitivity Tests; Quinazolinones; Structure-Activity Relationship; Topoisomerase II Inhibitors

2006
Fitness costs of fluoroquinolone resistance in Streptococcus pneumoniae.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2

    Topics: DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mutation; Pneumococcal Infections; Streptococcus pneumoniae; Transformation, Bacterial

2007
Synthesis and antibacterial activities of new quinolone derivatives utilizing 1-azabicyclo[1.1.0]butane.
    Bioorganic & medicinal chemistry letters, 2007, Feb-15, Volume: 17, Issue:4

    Topics: Anti-Bacterial Agents; Aza Compounds; Bridged Bicyclo Compounds; Crystallography, X-Ray; Indicators and Reagents; Magnetic Resonance Spectroscopy; Methicillin Resistance; Microbial Sensitivity Tests; Models, Molecular; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Structure-Activity Relationship

2007
First report of plasmid-mediated qnrA1 in a ciprofloxacin-resistant Escherichia coli strain in Latin America.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Conjugation, Genetic; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Integrons; Latin America; Molecular Sequence Data; Plasmids

2007
In vitro and in vivo activities of PD 0305970 and PD 0326448, new bacterial gyrase/topoisomerase inhibitors with potent antibacterial activities versus multidrug-resistant gram-positive and fastidious organism groups.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Drug Resistance, Multiple; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Microbial Sensitivity Tests; Pyrrolidines; Quinazolinones; Topoisomerase II Inhibitors

2007
Synthesis and antibacterial activity of 4,5,6,7-tetrahydro-thieno[3,2-c]pyridine quinolones.
    Bioorganic & medicinal chemistry letters, 2007, Apr-01, Volume: 17, Issue:7

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Chemistry, Pharmaceutical; Ciprofloxacin; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Microbial Sensitivity Tests; Models, Chemical; Molecular Conformation; Pyridines; Quinolones

2007
Expression and purification of an active form of the Mycobacterium leprae DNA gyrase and its inhibition by quinolones.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:5

    Topics: Anti-Infective Agents; DNA; DNA Gyrase; DNA, Superhelical; Enzyme Inhibitors; Mycobacterium leprae; Quinolones; Topoisomerase II Inhibitors

2007
Efficacy of fluoroquinolones against Leptospira interrogans in a hamster model.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Acute Disease; Animals; Anti-Bacterial Agents; Ciprofloxacin; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Doxycycline; Female; Fluoroquinolones; Gatifloxacin; Injections, Intraperitoneal; Leptospira interrogans; Leptospirosis; Levofloxacin; Mesocricetus; Ofloxacin; Serotyping; Survival Analysis

2007
Transferable resistance to aminoglycosides by methylation of G1405 in 16S rRNA and to hydrophilic fluoroquinolones by QepA-mediated efflux in Escherichia coli.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Amino Acid Motifs; Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Conjugation, Genetic; Conserved Sequence; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Genes, rRNA; Methylation; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Norfloxacin; Plasmids; Sequence Analysis, DNA; Sequence Homology, Amino Acid

2007
Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Acinetobacter; Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Brazil; Codon, Terminator; Cross Infection; Drug Resistance, Multiple, Bacterial; Gene Transfer, Horizontal; Genes, Bacterial; Hospitals; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Open Reading Frames; Plasmids; Pseudomonas putida; Transcription, Genetic

2007
New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chitosan; Conjugation, Genetic; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Humans; Malates; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Transformation, Bacterial; Uncoupling Agents

2007
Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8

    Topics: Anaerobiosis; Animals; Anti-Infective Agents; Bacterial Toxins; Cecum; Clostridioides difficile; Disease Models, Animal; Disease Outbreaks; Drug Resistance, Bacterial; Enterocolitis, Pseudomembranous; Fluoroquinolones; Humans; Mice; Microbial Sensitivity Tests

2007
Contributions of the combined effects of topoisomerase mutations toward fluoroquinolone resistance in Escherichia coli.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11

    Topics: DNA Topoisomerases; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Mutation

2007
Antimicrobial drug resistance of Salmonella enterica serovar typhi in asia and molecular mechanism of reduced susceptibility to the fluoroquinolones.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Anti-Bacterial Agents; Asia; Bangladesh; China; DNA Gyrase; DNA Mutational Analysis; DNA Topoisomerase IV; Drug Resistance, Microbial; Fluoroquinolones; Humans; India; Indonesia; Laos; Microbial Sensitivity Tests; Mutation; Nepal; Pakistan; Salmonella typhi; Vietnam

2007
Complex class 1 integrons with diverse variable regions, including aac(6')-Ib-cr, and a novel allele, qnrB10, associated with ISCR1 in clinical enterobacterial isolates from Argentina.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Alleles; Amino Acid Sequence; Argentina; Bacterial Proteins; Base Sequence; beta-Lactamases; Cross Infection; DNA Transposable Elements; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid

2007
In vitro activity of DC-159a, a new broad-spectrum fluoroquinolone, compared with that of other agents against drug-susceptible and -resistant pneumococci.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Culture Media; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mutation; Streptococcus pneumoniae

2008
Antimycobacterial activities of novel 1-(cyclopropyl/tert-butyl/4-fluorophenyl)-1,4-dihydro- 6-nitro-4-oxo-7-(substituted secondary amino)-1,8-naphthyridine-3-carboxylic acid.
    Journal of medicinal chemistry, 2007, Nov-29, Volume: 50, Issue:24

    Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Drug Resistance, Multiple, Bacterial; Female; Light; Mice; Microbial Sensitivity Tests; Mycobacterium smegmatis; Mycobacterium tuberculosis; Naphthyridines; Structure-Activity Relationship; Topoisomerase II Inhibitors; Vero Cells

2007
Evaluation of a 2-pyridone, KRQ-10018, against Mycobacterium tuberculosis in vitro and in vivo.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4

    Topics: Animals; Antitubercular Agents; Biological Availability; Interferon-gamma; Mice; Mice, Inbred C57BL; Mice, Knockout; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyridones; Quinolones; Treatment Outcome; Tuberculosis, Pulmonary

2008
Emergence of fluoroquinolone resistance in group B streptococcal isolates in Taiwan.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5

    Topics: Bacterial Proteins; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Streptococcus agalactiae; Taiwan

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
In vitro evaluation of CBR-2092, a novel rifamycin-quinolone hybrid antibiotic: studies of the mode of action in Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7

    Topics: Anti-Bacterial Agents; Bacterial Proteins; DNA Topoisomerase IV; DNA-Directed RNA Polymerases; DNA, Bacterial; Drug Resistance, Bacterial; Enzyme Inhibitors; Microbial Sensitivity Tests; Molecular Structure; Mutation; Quinolones; Rifamycins; RNA, Bacterial; Staphylococcus aureus; Topoisomerase II Inhibitors

2008
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Clostridium difficile infections in a Canadian tertiary care hospital before and during a regional epidemic associated with the BI/NAP1/027 strain.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9

    Topics: Adult; Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Community-Acquired Infections; Cross Infection; Disease Outbreaks; Drug Resistance, Bacterial; Enterocolitis, Pseudomembranous; Female; Hospitalization; Humans; Incidence; Male; Middle Aged; Prognosis; Quebec; Ribotyping; Risk Factors

2008
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids

2008
Smqnr, a new chromosome-carried quinolone resistance gene in Stenotrophomonas maltophilia.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Alleles; Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Chromosomes, Bacterial; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Genes, Bacterial; Gram-Negative Bacterial Infections; Humans; Molecular Sequence Data; Sequence Homology, Amino Acid; Stenotrophomonas maltophilia

2008
Bisphosphonated fluoroquinolone esters as osteotropic prodrugs for the prevention of osteomyelitis.
    Bioorganic & medicinal chemistry, 2008, Oct-15, Volume: 16, Issue:20

    Topics: Animals; Disease Models, Animal; Esters; Female; Fluoroquinolones; Humans; Molecular Structure; Organophosphonates; Osteomyelitis; Prodrugs; Rats

2008
Linking bisphosphonates to the free amino groups in fluoroquinolones: preparation of osteotropic prodrugs for the prevention of osteomyelitis.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Amines; Animals; Cell Line; Diphosphonates; Female; Fluoroquinolones; Molecular Structure; Osteomyelitis; Prodrugs; Rats; Structure-Activity Relationship

2008
Mechanisms accounting for fluoroquinolone resistance in Escherichia coli clinical isolates.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Escherichia coli; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Norfloxacin; Ofloxacin

2009
Relationships among ciprofloxacin, gatifloxacin, levofloxacin, and norfloxacin MICs for fluoroquinolone-resistant Escherichia coli clinical isolates.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; United States

2009
Comparative antipneumococcal activities of sulopenem and other drugs.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Lactams; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Streptococcus pneumoniae

2009
Emergence of quinolone-resistant Bordetella pertussis in Japan.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7

    Topics: Anti-Bacterial Agents; Bordetella pertussis; Child; DNA Gyrase; Fluoroquinolones; Humans; Japan; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Quinolones

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
In vitro activity of garenoxacin against Streptococcus pneumoniae mutants with characterized resistance mechanisms.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8

    Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerases; Drug Resistance, Bacterial; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Streptococcus pneumoniae

2009
Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8

    Topics: Anti-Bacterial Agents; Azepines; Bacteria, Anaerobic; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests

2009
Interaction of drug based binuclear mixed-ligand complexes with DNA.
    Bioorganic & medicinal chemistry, 2009, Aug-01, Volume: 17, Issue:15

    Topics: Anti-Bacterial Agents; Bacteria; Binding Sites; Ciprofloxacin; Cobalt; DNA, Bacterial; Ligands; Magnetic Resonance Spectroscopy; Magnetics; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Structure; Oxidation-Reduction; Spectrophotometry, Infrared; Structure-Activity Relationship; Temperature; Viscosity

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents.
    Bioorganic & medicinal chemistry, 2009, Aug-01, Volume: 17, Issue:15

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Ciprofloxacin; Humans; Maximum Tolerated Dose; Mice; Neoplasms; Piperazine; Piperazines

2009
Design, synthesis and biological evaluations of novel 7-[3-(1-aminocycloalkyl)pyrrolidin-1-yl]-6-desfluoro-8-methoxyquinolones with potent antibacterial activity against multi-drug resistant Gram-positive bacteria.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Anti-Bacterial Agents; Drug Design; Drug Resistance, Multiple; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quinolones; Structure-Activity Relationship

2009
In vitro activity of a new quinoline derivative, ER-2, against clinical isolates of Mycoplasma pneumoniae and Mycoplasma hominis.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Anti-Bacterial Agents; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycoplasma hominis; Mycoplasma pneumoniae; Pneumonia, Mycoplasma; Quinolines

2009
Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11

    Topics: Microbial Sensitivity Tests; Mycoplasma genitalium; Polymerase Chain Reaction

2009
SmQnr contributes to intrinsic resistance to quinolones in Stenotrophomonas maltophilia.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1

    Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Mutation; Plasmids; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Stenotrophomonas maltophilia

2010
Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach.
    Journal of medicinal chemistry, 2009, Dec-24, Volume: 52, Issue:24

    Topics: Aminoquinolines; Antimalarials; Ciprofloxacin; Ferrous Compounds; Metallocenes; Plasmodium falciparum; Prodrugs

2009
The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability.
    Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1

    Topics: Caco-2 Cells; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Membranes, Artificial; Molecular Structure; Pharmaceutical Preparations

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
In vitro activity of the aminoglycoside antibiotic arbekacin against Acinetobacter baumannii-calcoaceticus isolated from war-wounded patients at Walter Reed Army Medical Center.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7

    Topics: Acinetobacter baumannii; Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Dibekacin; Hospitals, Military; Humans; Microbial Sensitivity Tests; Warfare

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Synthesis of gatifloxacin derivatives and their biological activities against Mycobacterium leprae and Mycobacterium tuberculosis.
    Bioorganic & medicinal chemistry, 2013, Feb-15, Volume: 21, Issue:4

    Topics: Antitubercular Agents; Aza Compounds; DNA Cleavage; DNA Gyrase; Fluoroquinolones; Gatifloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium leprae; Mycobacterium tuberculosis; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors

2013
The synergic modeling for the binding of fluoroquinolone antibiotics to the hERG potassium channel.
    Bioorganic & medicinal chemistry letters, 2013, Jul-01, Volume: 23, Issue:13

    Topics: Anti-Bacterial Agents; Binding Sites; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Humans; Models, Molecular; Potassium Channel Blockers; Structure-Activity Relationship

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a Dual-Acting Antibacterial Agent (TNP-2092) for the Treatment of Persistent Bacterial Infections.
    Journal of medicinal chemistry, 2016, 07-28, Volume: 59, Issue:14

    Topics: Anti-Bacterial Agents; Bacterial Infections; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Rifamycins; Staphylococcus aureus; Structure-Activity Relationship

2016
Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis.
    European journal of medicinal chemistry, 2017, Feb-15, Volume: 127

    Topics: Anti-Bacterial Agents; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mycobacterium smegmatis; Triazenes

2017
Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents.
    European journal of medicinal chemistry, 2019, Oct-01, Volume: 179

    Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Positive Bacteria; HEK293 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Quaternary Ammonium Compounds; Quinolones; Structure-Activity Relationship

2019
Synthesis of Novel Ciprofloxacin-Based Hybrid Molecules toward Potent Antimalarial Activity.
    ACS medicinal chemistry letters, 2020, Jul-09, Volume: 11, Issue:7

    Topics:

2020
Synthesis and evaluation of dual-action kanglemycin-fluoroquinolone hybrid antibiotics.
    Bioorganic & medicinal chemistry letters, 2022, 02-01, Volume: 57

    Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; HEK293 Cells; Humans; Microbial Sensitivity Tests; Rifamycins; Staphylococcus aureus

2022
WCK 1152, WCK 1153: Discovery and structure activity relationship for the treatment of resistant pneumococcal and staphylococcal respiratory infections.
    Bioorganic & medicinal chemistry letters, 2022, 05-01, Volume: 63

    Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Piperidines; Respiratory Tract Infections; Staphylococcal Infections; Staphylococcus; Streptococcus pneumoniae; Structure-Activity Relationship

2022
In vitro and in vivo antibacterial activities of AM-1155, a new 6-fluoro-8-methoxy quinolone.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:10

    Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; DNA Topoisomerases, Type II; Drug Evaluation, Preclinical; Fluoroquinolones; Gatifloxacin; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Piperazines; Quinolones; Tissue Distribution

1992
Effect of 6-fluoro-8-methoxy quinolone (AM-1155) against chronic airway infection with Pseudomonas aeruginosa in a rat model.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:2

    Topics: Animals; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Disease Models, Animal; Fluoroquinolones; Gatifloxacin; Immunoglobulin A; Immunoglobulin G; Male; Piperazines; Pseudomonas Infections; Quinolones; Rats; Rats, Sprague-Dawley; Tracheal Diseases

1997
The activity of the methylpiperazinyl fluoroquinolone CG 5501: a comparison with other fluoroquinolones.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacteroides fragilis; Chlamydia; Ciprofloxacin; Clarithromycin; Doxycycline; Enterobacter; Erythromycin; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Haemophilus influenzae; Microbial Sensitivity Tests; Naphthyridines; Piperazines; Pseudomonas aeruginosa; Quinolones; Streptococcus pneumoniae

1997
Comparison of the antibacterial activities of the quinolones Bay 12-8039, gatifloxacin (AM 1155), trovafloxacin, clinafloxacin, levofloxacin and ciprofloxacin.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 40, Issue:5

    Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Quinolones; Staphylococcus aureus

1997
Antimicrobial activity of gatifloxacin tested against 1676 strains of ciprofloxacin-resistant gram-positive cocci isolated from patient infections in North and South America.
    Diagnostic microbiology and infectious disease, 1998, Volume: 32, Issue:3

    Topics: Anti-Infective Agents; Antitubercular Agents; Bacteriological Techniques; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Naphthyridines; North America; Quinolones; South America

1998
In vitro activity of gatifloxacin, compared with ciprofloxacin, clarithromycin, erythromycin, and rifampin, against Legionella species.
    Diagnostic microbiology and infectious disease, 1999, Volume: 33, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Ciprofloxacin; Clarithromycin; Drug Resistance, Microbial; Erythromycin; Fluoroquinolones; Gatifloxacin; Legionella; Microbial Sensitivity Tests; Rifampin

1999
Anti-pneumococcal activity of gatifloxacin compared with other quinolone and non-quinolone agents.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:5

    Topics: Amoxicillin; Anti-Infective Agents; Ceftriaxone; Cefuroxime; Cephalosporins; Ciprofloxacin; Clarithromycin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Penicillin Resistance; Streptococcus pneumoniae

1999
Comparative in vitro activities of ciprofloxacin, clinafloxacin, gatifloxacin, levofloxacin, moxifloxacin, and trovafloxacin against Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, and Enterobacter aerogenes clinical isolates with alterat
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:8

    Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Enterobacter cloacae; Fluoroquinolones; Gatifloxacin; Humans; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Molecular Sequence Data; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines

1999
In-vitro activity of gatifloxacin, a novel fluoroquinolone, compared with that of ciprofloxacin against Legionella spp.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 44, Issue:2

    Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Humans; Legionella; Microbial Sensitivity Tests

1999
Activities of trovafloxacin, gatifloxacin, clinafloxacin, sparfloxacin, levofloxacin, and ciprofloxacin against penicillin-resistant Streptococcus pneumoniae in an in vitro infection model.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3

    Topics: Anti-Infective Agents; Blood Coagulation; Ciprofloxacin; Fibrin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Penicillin Resistance; Pneumococcal Infections; Streptococcus pneumoniae

2000
Comparative pharmacodynamics of gatifloxacin and ciprofloxacin in an in vitro dynamic model: prediction of equiefficient doses and the breakpoints of the area under the curve/MIC ratio.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:4

    Topics: Anti-Infective Agents; Area Under Curve; Bacteria; Ciprofloxacin; Computer Simulation; Escherichia coli; Fluoroquinolones; Gatifloxacin; Half-Life; Humans; Klebsiella pneumoniae; Models, Biological; Staphylococcus aureus

2000
Comparative activities of ciprofloxacin, clinafloxacin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin, and trovafloxacin against epidemiologically defined Acinetobacter baumannii strains.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:8

    Topics: Acinetobacter; Acinetobacter Infections; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Disease Outbreaks; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Germany; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines

2000
In vitro activity of gatifloxacin compared with gemifloxacin, moxifloxacin, trovafloxacin, ciprofloxacin and ofloxacin against uropathogens cultured from patients with complicated urinary tract infections.
    International journal of antimicrobial agents, 2000, Volume: 16, Issue:3

    Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Escherichia coli; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Klebsiella; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Urinary Tract Infections

2000
Susceptibility of bacterial isolates to gatifloxacin and ciprofloxacin from clinical trials 1997-1998.
    International journal of antimicrobial agents, 2000, Volume: 16, Issue:4

    Topics: Anti-Infective Agents; Ciprofloxacin; Clinical Trials as Topic; Enterobacteriaceae; Fluoroquinolones; Gatifloxacin; Humans; Microbial Sensitivity Tests; Staphylococcus aureus; Streptococcus pneumoniae

2000
Activity of gatifloxacin and ciprofloxacin in combination with other antimicrobial agents.
    International journal of antimicrobial agents, 2001, Volume: 17, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Antagonism; Drug Combinations; Drug Interactions; Drug Synergism; Enterococcus faecalis; Escherichia coli; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus; Streptococcus pneumoniae

2001
Determination of gatifloxacin in human plasma by liquid chromatography/electrospray tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2001, Volume: 15, Issue:12

    Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Time Factors

2001
Can antimicrobial susceptibility testing results for ciprofloxacin or levofloxacin predict susceptibility to a newer fluoroquinolone, gatifloxacin?: Report from The SENTRY Antimicrobial Surveillance Program (1997-99).
    Diagnostic microbiology and infectious disease, 2001, Volume: 39, Issue:4

    Topics: Anti-Infective Agents; Ciprofloxacin; Databases, Factual; Enterobacteriaceae; Fluoroquinolones; Gatifloxacin; Gram-Positive Cocci; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Predictive Value of Tests; Pseudomonas aeruginosa

2001
Activity of BMS284756 against 2,681 recent clinical isolates of Haemophilus influenzae and Moraxella catarrhalis: Report from The SENTRY Antimicrobial Surveillance Program (2000) in Europe, Canada and the United States.
    Diagnostic microbiology and infectious disease, 2001, Volume: 39, Issue:4

    Topics: Anti-Infective Agents; Aza Compounds; Canada; Ciprofloxacin; Europe; Fluoroquinolones; Gatifloxacin; Haemophilus influenzae; Humans; Indoles; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; United States

2001
Activity of gatifloxacin against strains resistant to ofloxacin and ciprofloxacin and its ability to select for less susceptible bacterial variants.
    International journal of antimicrobial agents, 2001, Volume: 18, Issue:1

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Escherichia coli; Fluoroquinolones; Gatifloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Mutation; Neisseria gonorrhoeae; Ofloxacin; Staphylococcus aureus; Streptococcus pneumoniae

2001
Propensity of fluoroquinolones with different moieties at position 8 to cause resistance development in clinical isolates of Streptococcus pneumoniae.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:9

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Streptococcus pneumoniae

2001
Single- and multi-step resistance selection study of gemifloxacin compared with trovafloxacin, ciprofloxacin, gatifloxacin and moxifloxacin in Streptococcus pneumoniae.
    The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:3

    Topics: Anti-Infective Agents; Aza Compounds; Biological Transport; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Naphthyridines; Quinolines; Selection, Genetic; Serotyping; Streptococcus pneumoniae

2001
Mechanisms and frequency of resistance to gatifloxacin in comparison to AM-1121 and ciprofloxacin in Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:10

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gene Frequency; Genes, Bacterial; Genetic Linkage; Genotype; Microbial Sensitivity Tests; Mutation; Phenotype; Staphylococcus aureus

2001
The pharmacodynamics of gatifloxacin and ciprofloxacin for pneumococci in an in vitro dynamic model: prediction of equiefficient doses.
    The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:6

    Topics: Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Dose-Response Relationship, Drug; Fluoroquinolones; Gatifloxacin; Humans; Microbial Sensitivity Tests; Models, Biological; Streptococcus pneumoniae

2001
Comparative antimicrobial activity of gatifloxacin with ciprofloxacin and beta-lactams against gram-positive bacteria.
    Diagnostic microbiology and infectious disease, 2001, Volume: 41, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactams; Ciprofloxacin; Enterococcus; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Staphylococcus; Streptococcus

2001
Spectrum and activity of three contemporary fluoroquinolones tested against Pseudomonas aeruginosa isolates from urinary tract infections in the SENTRY Antimicrobial Surveillance Program (Europe and the Americas; 2000): more alike than different!
    Diagnostic microbiology and infectious disease, 2001, Volume: 41, Issue:3

    Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Drug Resistance, Bacterial; Europe; Fluoroquinolones; Gatifloxacin; Humans; Lactams; Latin America; Levofloxacin; Microbial Sensitivity Tests; North America; Ofloxacin; Population Surveillance; Pseudomonas aeruginosa; Pseudomonas Infections; Regional Medical Programs; Urinary Tract Infections

2001
Rates of torsades de pointes associated with ciprofloxacin, ofloxacin, levofloxacin, gatifloxacin, and moxifloxacin.
    Pharmacotherapy, 2001, Volume: 21, Issue:12

    Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Electrocardiography; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Retrospective Studies; Torsades de Pointes

2001
[Activity of new fluoroquinolones against clinical isolates of Acinetobacter baumannii].
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2001, Volume: 14, Issue:4

    Topics: Acinetobacter; Acinetobacter Infections; Ampicillin; Anti-Infective Agents; Aza Compounds; Cefepime; Cephalosporins; Ciprofloxacin; Colistin; Fluoroquinolones; Gatifloxacin; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Moxifloxacin; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Opportunistic Infections; Quinolines; Sulbactam; Thienamycins

2001
Fourth generation fluoroquinolones: new weapons in the arsenal of ophthalmic antibiotics.
    American journal of ophthalmology, 2002, Volume: 133, Issue:4

    Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Endophthalmitis; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Retrospective Studies

2002
Comparative activity of gatifloxacin and other antibiotics against 4009 clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000.
    Diagnostic microbiology and infectious disease, 2002, Volume: 43, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Ceftriaxone; Child; Ciprofloxacin; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Penicillin Resistance; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae; United States

2002
Comparison of in vitro activities of gatifloxacin and ciprofloxacin against four taxa of rapidly growing mycobacteria.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:10

    Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Humans; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium chelonae; Mycobacterium fortuitum

2002
Comparative killing rates of gatifloxacin and ciprofloxacin against 14 clinical isolates: impact of bacterial strain and antibiotic concentration.
    Diagnostic microbiology and infectious disease, 2002, Volume: 44, Issue:1

    Topics: Anti-Infective Agents; Blood Bactericidal Activity; Ciprofloxacin; Dose-Response Relationship, Drug; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Sensitivity and Specificity

2002
In vitro activity of gemifloxacin against recent clinical isolates of bacteria in Korea.
    Journal of Korean medical science, 2002, Volume: 17, Issue:6

    Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Haemophilus influenzae; Korea; Levofloxacin; Microbial Sensitivity Tests; Moraxella; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae

2002
[In vitro antibacterial activity of prulifloxacin, a new oral fluoroquinolone].
    The Japanese journal of antibiotics, 2002, Volume: 55, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dosage Forms; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fleroxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Piperazines; Prodrugs; Quinolones

2002
[In vitro short-term bactericidal activity and accumulation of NM394, the active metabolite of prulifloxacin, for Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa: comparison with ciprofloxacin, levofloxacin, and gatifloxacin].
    The Japanese journal of antibiotics, 2002, Volume: 55, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Gatifloxacin; Levofloxacin; Ofloxacin; Piperazines; Prodrugs; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Time Factors

2002
[Antibacterial activity of gatifloxacin against various fresh clinical isolates in 2002].
    The Japanese journal of antibiotics, 2002, Volume: 55, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Cefdinir; Cephalosporins; Ciprofloxacin; Dosage Forms; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Macrolides; Ofloxacin; Otorhinolaryngologic Diseases; Respiratory Tract Infections; Staphylococcus aureus; Streptococcus pneumoniae; Time Factors; Urinary Tract Infections

2002
[Inhibitory activity of NM394, the active form of prodrug prulifloxacin against type II topoisomerase from Pseudomonas aeruginosa].
    The Japanese journal of antibiotics, 2002, Volume: 55, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Fluoroquinolones; Gatifloxacin; Levofloxacin; Ofloxacin; Piperazines; Prodrugs; Pseudomonas aeruginosa; Quinolones; Topoisomerase II Inhibitors

2002
[Pneumococcus and quinolone resistance].
    Archivos de bronconeumologia, 2003, Volume: 39, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Child, Preschool; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Genes, Bacterial; Humans; Male; Microbial Sensitivity Tests; Moxifloxacin; Multivariate Analysis; Mutation; Ofloxacin; Penicillin Resistance; Penicillins; Pneumococcal Infections; Pneumonia, Pneumococcal; Quinolines; Recurrence; Risk Factors; Streptococcus pneumoniae

2003
In vitro and in vivo activities of fluoroquinolones against Aeromonas hydrophila.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:7

    Topics: Aeromonas hydrophila; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Cefotaxime; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacterial Infections; Humans; In Vitro Techniques; Levofloxacin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Ofloxacin; Quinolines; Quinolones

2003
Fluoroquinolone therapy in multiple-drug resistant staphylococcal keratitis after lamellar keratectomy in a rabbit model.
    American journal of ophthalmology, 2003, Volume: 136, Issue:1

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Corneal Stroma; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Keratitis; Keratomileusis, Laser In Situ; Levofloxacin; Ofloxacin; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Surgical Flaps

2003
Antimicrobial susceptibilities of 40 isolates of Bacillus anthracis isolated in Turkey.
    International journal of antimicrobial agents, 2003, Volume: 22, Issue:1

    Topics: Anthrax; Anti-Bacterial Agents; Bacillus anthracis; Ciprofloxacin; Doxycycline; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin G; Penicillins; Turkey

2003
Accumulation of garenoxacin by Bacteroides fragilis compared with that of five fluoroquinolones.
    The Journal of antimicrobial chemotherapy, 2003, Volume: 52, Issue:4

    Topics: Aza Compounds; Bacteroides fragilis; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Membrane Transport Modulators; Membrane Transport Proteins; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines

2003
Gatifloxacin and moxifloxacin: an in vitro susceptibility comparison to levofloxacin, ciprofloxacin, and ofloxacin using bacterial keratitis isolates.
    American journal of ophthalmology, 2003, Volume: 136, Issue:3

    Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Corneal Ulcer; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines

2003
The effect of pharmacokinetic/pharmacodynamic (PK/PD) parameters of gatifloxacin on its bactericidal activity and resistance selectivity against clinical isolates of Streptococcus pneumoniae.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2003, Volume: 9, Issue:3

    Topics: Administration, Oral; Area Under Curve; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Theoretical; Ofloxacin; Streptococcus pneumoniae

2003
[Comparative in vitro activity of garenoxacin (BMS-284756). Sentry program, Spain (1999-2000)].
    Enfermedades infecciosas y microbiologia clinica, 2003, Volume: 21, Issue:8

    Topics: Anti-Infective Agents; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Species Specificity; Staphylococcus aureus; Streptococcus pneumoniae

2003
Gatifloxacin, gemifloxacin, and moxifloxacin: the role of 3 newer fluoroquinolones.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Nov-01, Volume: 37, Issue:9

    Topics: Aza Compounds; Bacteroides fragilis; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae

2003
In vivo efficacy of a new quinolone, DQ-113, against Streptococcus pneumoniae in a mouse model.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:12

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Lung; Male; Mice; Mice, Inbred CBA; Microbial Sensitivity Tests; Penicillin Resistance; Pneumonia, Pneumococcal; Quinolones; Survival Analysis

2003
[Analysis of the response factors of different quinolones detected by evaporative light-scattering detector].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:9

    Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Light; Linear Models; Ofloxacin; Quinolones

2003
Susceptibility testing of Singapore strains of Mycoplasma hominis to tetracycline, gatifloxacin, moxifloxacin, ciprofloxacin, clindamycin, and azithromycin by the Etest method.
    Diagnostic microbiology and infectious disease, 2004, Volume: 48, Issue:3

    Topics: Anti-Bacterial Agents; Aza Compounds; Azithromycin; Ciprofloxacin; Clindamycin; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mycoplasma hominis; Quinolines; Sampling Studies; Sensitivity and Specificity; Singapore; Tetracycline

2004
Mutations in the gyrA and parC genes and in vitro activities of fluoroquinolones in 91 clinical isolates of Neisseria gonorrhoeae in Japan.
    Sexually transmitted diseases, 2004, Volume: 31, Issue:3

    Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gonorrhea; Humans; Japan; Levofloxacin; Male; Microbial Sensitivity Tests; Mutation; Neisseria gonorrhoeae; Ofloxacin

2004
Post-exposure prophylaxis of systemic anthrax in mice and treatment with fluoroquinolones.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:1

    Topics: Animals; Anthrax; Anti-Infective Agents; Aza Compounds; Bacillus anthracis; Ciprofloxacin; Female; Fluoroquinolones; Gatifloxacin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Moxifloxacin; Quinolines; Survival Analysis

2004
[Synthesis and antibacterial activity of 7-(7-aminomethyl-5-azaspiro [2,4] hept-5-yl)-1-cyclopropyl-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid and its analogues].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2004, Volume: 39, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Female; Fluoroquinolones; Gatifloxacin; Male; Mice; Mice, Inbred ICR; Molecular Conformation; Molecular Structure; Quinolines; Spiro Compounds; Staphylococcus aureus; Streptococcus pneumoniae

2004
Pharmacodynamics and bactericidal activity of gatifloxacin in experimental pneumonia caused by penicillin-resistant Streptococcus pneumoniae.
    Chemotherapy, 2004, Volume: 50, Issue:3

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Fluoroquinolones; Gatifloxacin; Levofloxacin; Lung; Mice; Mice, Inbred CBA; Ofloxacin; Penicillin Resistance; Pneumonia, Pneumococcal; Survival Rate

2004
Comparative efficacy of topical gatifloxacin with ciprofloxacin, amikacin, and clarithromycin in the treatment of experimental Mycobacterium chelonae keratitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2004, Volume: 122, Issue:8

    Topics: Administration, Topical; Amikacin; Animals; Anti-Bacterial Agents; Ciprofloxacin; Clarithromycin; Cornea; Corneal Ulcer; Disease Models, Animal; Drug Therapy, Combination; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Male; Mycobacterium chelonae; Mycobacterium Infections, Nontuberculous; Ophthalmic Solutions; Rabbits

2004
Efficacy of the latest fluoroquinolones against experimental Yersinia pestis.
    International journal of antimicrobial agents, 2004, Volume: 24, Issue:6

    Topics: Animals; Ciprofloxacin; Disease Models, Animal; Fluoroquinolones; Gatifloxacin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Plague; Yersinia pestis

2004
Pharmacodynamic modeling of carbapenems and fluoroquinolones against bacteria that produce extended-spectrum beta-lactamases.
    Clinical therapeutics, 2004, Volume: 26, Issue:11

    Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Ciprofloxacin; Drug Resistance, Bacterial; Ertapenem; Escherichia coli; Fluoroquinolones; Gatifloxacin; Humans; Imipenem; Klebsiella pneumoniae; Lactams; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Models, Biological; Monte Carlo Method; Ofloxacin; Thienamycins

2004
Stable antimicrobial susceptibility rates for clinical isolates of Pseudomonas aeruginosa from the 2001-2003 tracking resistance in the United States today surveillance studies.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Feb-15, Volume: 40 Suppl 2

    Topics: beta-Lactams; Ceftazidime; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gatifloxacin; Gentamicins; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; United States

2005
Comparison of ophthalmic gatifloxacin 0.3% and ciprofloxacin 0.3% in healing of corneal ulcers associated with Pseudomonas aeruginosa-induced ulcerative keratitis in rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2005, Volume: 21, Issue:1

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Cornea; Corneal Ulcer; Disease Models, Animal; Eye Infections, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Ophthalmic Solutions; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Safety; Treatment Outcome; Wound Healing

2005
Comparison of gatifloxacin, moxifloxacin and ciprofloxacin for treatment of experimental Burkholderia pseudomallei infection.
    The Journal of antimicrobial chemotherapy, 2005, Volume: 55, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Dexamethasone; Drug Administration Schedule; Female; Fluoroquinolones; Gatifloxacin; Glucocorticoids; Melioidosis; Mice; Mice, Inbred BALB C; Moxifloxacin; Quinolines

2005
Acinetobacter as a causative agent in preseptal cellulitis.
    Optometry (St. Louis, Mo.), 2005, Volume: 76, Issue:3

    Topics: Acinetobacter; Acinetobacter Infections; Adult; Anti-Infective Agents; Cellulitis; Ciprofloxacin; Drug Therapy, Combination; Eye Infections, Bacterial; Eyelid Diseases; Female; Fluoroquinolones; Gatifloxacin; Humans

2005
In vitro activity of fluoroquinolones against Mycobacterium tuberculosis.
    Journal of chemotherapy (Florence, Italy), 2005, Volume: 17, Issue:2

    Topics: Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Quinolones; Sampling Studies; Sensitivity and Specificity

2005
In vitro synergy of ciprofloxacin and gatifloxacin against ciprofloxacin-resistant Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:7

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Drug Synergism; Fluoroquinolones; Gatifloxacin; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa

2005
Fluoroquinolone therapy in Mycobacterium chelonae keratitis after lamellar keratectomy.
    Journal of cataract and refractive surgery, 2005, Volume: 31, Issue:7

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Cornea; Corneal Transplantation; Disease Models, Animal; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Keratitis; Levofloxacin; Mycobacterium chelonae; Mycobacterium Infections, Nontuberculous; Ofloxacin; Rabbits

2005
Evaluation of moxifloxacin, ciprofloxacin, gatifloxacin, ofloxacin, and levofloxacin concentrations in human conjunctival tissue.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2005, Volume: 123, Issue:9

    Topics: Anti-Bacterial Agents; Aza Compounds; Biopsy; Ciprofloxacin; Conjunctiva; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Ophthalmic Solutions; Quinolines; Tissue Distribution

2005
A retrospective, comparative evaluation of dysglycemias in hospitalized patients receiving gatifloxacin, levofloxacin, ciprofloxacin, or ceftriaxone.
    Pharmacotherapy, 2005, Volume: 25, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Blood Glucose; Ceftriaxone; Ciprofloxacin; Female; Fluoroquinolones; Gatifloxacin; Humans; Hyperglycemia; Hypoglycemia; Levofloxacin; Male; Middle Aged; Ofloxacin; Product Surveillance, Postmarketing; Retrospective Studies

2005
Glucose homeostasis abnormalities associated with use of gatifloxacin.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Nov-01, Volume: 41, Issue:9

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Child; Ciprofloxacin; Female; Fluoroquinolones; Gatifloxacin; Glucose; Homeostasis; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines

2005
In vivo efficacy of fluoroquinolones against systemic tularaemia infection in mice.
    The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:6

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Colony Count, Microbial; Dexamethasone; Disease Models, Animal; Female; Fluoroquinolones; Francisella tularensis; Gatifloxacin; Mice; Mice, Inbred BALB C; Moxifloxacin; Quinolines; Survival Analysis; Tularemia

2005
Rapid detection of fluoroquinolone resistance by isothermal chimeric primer-initiated amplification of nucleic acids from clinical isolates of Neisseria gonorrhoeae.
    Journal of microbiological methods, 2006, Volume: 65, Issue:3

    Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA Primers; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Nucleic Acid Amplification Techniques; Point Mutation; Time Factors

2006
Development and validation of an HPLC method for the determination of gatifloxacin stability in human plasma.
    Journal of pharmaceutical and biomedical analysis, 2006, Apr-11, Volume: 41, Issue:1

    Topics: Acetonitriles; Calibration; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Stability; Fluoroquinolones; Gatifloxacin; Humans; Models, Chemical; Phosphoric Acids; Quality Control; Reproducibility of Results; Spectrophotometry; Time Factors

2006
Pharmacodynamic assessment of the activity of high-dose (750 mg) levofloxacin, ciprofloxacin, and gatifloxacin against clinical strains of Pseudomonas aeruginosa.
    Diagnostic microbiology and infectious disease, 2006, Volume: 54, Issue:1

    Topics: Anti-Infective Agents; Area Under Curve; Ciprofloxacin; DNA, Bacterial; Evaluation Studies as Topic; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa

2006
A comparison of gatifloxacin to ciprofloxacin in the prophylaxis of Streptococcus pneumoniae in rabbits in a LASIK model.
    Eye & contact lens, 2006, Volume: 32, Issue:1

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Cornea; Disease Models, Animal; Eye Infections, Bacterial; Fluoroquinolones; Follow-Up Studies; Gatifloxacin; Keratitis; Keratomileusis, Laser In Situ; Ophthalmic Solutions; Pneumococcal Infections; Rabbits; Streptococcus pneumoniae; Surgical Wound Infection; Treatment Outcome

2006
Efficacy of quinolones against secondary pneumococcal pneumonia after influenza virus infection in mice.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:2

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Female; Fluoroquinolones; Gatifloxacin; Lung; Mice; Mice, Inbred BALB C; Ofloxacin; Orthomyxoviridae Infections; Pneumonia, Pneumococcal

2006
Comparative study of antimicrobial release kinetics from polymethylmethacrylate.
    Clinical orthopaedics and related research, 2006, Volume: 445

    Topics: Acetamides; Anti-Bacterial Agents; Area Under Curve; Cefazolin; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Linezolid; Ofloxacin; Oxazolidinones; Polymethyl Methacrylate; Rifampin

2006
Treatment of murine pneumonic Francisella tularensis infection with gatifloxacin, moxifloxacin or ciprofloxacin.
    International journal of antimicrobial agents, 2006, Volume: 27, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Female; Fluoroquinolones; Gatifloxacin; Mice; Mice, Inbred BALB C; Moxifloxacin; Pneumonia, Bacterial; Quinolines; Tularemia

2006
Activity of gatifloxacin in an in vitro pharmacokinetic-pharmacodynamic model against Staphylococcus aureus strains either susceptible to ciprofloxacin or exhibiting various levels and mechanisms of ciprofloxacin resistance.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:6

    Topics: Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Computer Simulation; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Half-Life; In Vitro Techniques; Microbial Sensitivity Tests; Mutation; Reference Standards; Staphylococcus aureus

2006
Antipneumococcal activity of DW-224a, a new quinolone, compared to those of eight other agents.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:6

    Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Azithromycin; Cefuroxime; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Genes, Bacterial; Levofloxacin; Microbial Sensitivity Tests; Molecular Structure; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae

2006
Using interrupted time series analysis to assess associations of fluoroquinolone formulary changes with susceptibility of gram-negative pathogens and isolation rates of methicillin-resistant Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Cross Infection; Escherichia coli; Fluoroquinolones; Formularies as Topic; Gatifloxacin; Gram-Negative Bacteria; Humans; Levofloxacin; Methicillin; Methicillin Resistance; Ofloxacin; Pseudomonas aeruginosa; Regression Analysis; Retrospective Studies; Staphylococcus aureus

2006
In vitro activities of DX-619 and comparison quinolones against gram-positive cocci.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:6

    Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Enterococcus; Fluoroquinolones; Gatifloxacin; Gram-Positive Cocci; In Vitro Techniques; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Pyrrolidines; Quinolines; Quinolones; Staphylococcus aureus; Streptococcus pneumoniae; Streptococcus pyogenes

2006
Effectiveness of flouroquinolone therapy for gram-negative infections within the intensive care unit setting.
    The American journal of medicine, 2006, Volume: 119, Issue:6

    Topics: Acinetobacter; Alabama; Ciprofloxacin; Drug Resistance, Bacterial; Enterobacter cloacae; Escherichia coli; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hospitals, Community; Humans; Intensive Care Units; Klebsiella oxytoca; Microbial Sensitivity Tests; Ofloxacin; Proteus mirabilis; Pseudomonas aeruginosa; Retrospective Studies

2006
In vitro activity of fluoroquinolones against common respiratory pathogens.
    The West Indian medical journal, 2006, Volume: 55, Issue:1

    Topics: Aza Compounds; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Haemophilus influenzae; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Ofloxacin; Quinolines; Streptococcus pneumoniae

2006
Predictive efficacy of nalidixic acid resistance as a marker of fluoroquinolone resistance in Salmonella enterica var Typhi.
    The Indian journal of medical research, 2006, Volume: 124, Issue:1

    Topics: Biomarkers; Cefotaxime; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Salmonella typhi

2006
Fluoroquinolone resistance in Salmonella typhi and S. paratyphi A in Bangalore, India.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007, Volume: 101, Issue:3

    Topics: Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Salmonella paratyphi A; Salmonella typhi

2007
In vitro development of resistance to DX-619 and other quinolones in enterococci.
    The Journal of antimicrobial chemotherapy, 2006, Volume: 58, Issue:6

    Topics: Anti-Bacterial Agents; Aza Compounds; Bacterial Proteins; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Enterococcus faecalis; Enterococcus faecium; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Polymerase Chain Reaction; Pyrrolidines; Quinolines; Quinolones; Sequence Analysis, DNA

2006
Molecular characterization of increasing fluoroquinolone resistance in Streptococcus pneumoniae isolates in Canada, 1997 to 2005.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aza Compounds; Bacterial Proteins; Canada; Child; Child, Preschool; Ciprofloxacin; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Genotype; Humans; Infant; Infant, Newborn; Levofloxacin; Middle Aged; Moxifloxacin; Naphthyridines; Ofloxacin; Pneumococcal Infections; Quinolines; Serotyping; Streptococcus pneumoniae

2007
Evaluation of the penetration of fluoroquinolones in human conjunctival tissue.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2006, Volume: 124, Issue:12

    Topics: Anti-Bacterial Agents; Aza Compounds; Biopsy; Ciprofloxacin; Conjunctiva; Fluoroquinolones; Gatifloxacin; Humans; Moxifloxacin; Ofloxacin; Ophthalmic Solutions; Quinolines; Tissue Distribution

2006
[Study investigating the activity of several fluoroquinolones against Pseudomonas aeruginosa using the mutant prevention concentration].
    Enfermedades infecciosas y microbiologia clinica, 2006, Volume: 24, Issue:10

    Topics: Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Cross Infection; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Genes, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutagenicity Tests; Mutation; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolines

2006
Fluoroquinolone resistance among Salmonella enterica serovar Paratyphi A in Pondicherry.
    The Indian journal of medical research, 2006, Volume: 124, Issue:5

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Microbial Sensitivity Tests; Ofloxacin; Salmonella paratyphi A

2006
In vitro activity of fluoroquinolones against ocular bacterial isolates in São Paulo, Brazil.
    Cornea, 2007, Volume: 26, Issue:2

    Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Brazil; Ciprofloxacin; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; In Vitro Techniques; Incidence; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines

2007
Antacid interaction with new quinolones: dose regimen recommendations based on pharmacokinetic modeling of clinical data for ciprofloxacin, gatifloxacin and norfloxacin and metal cations.
    International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:1

    Topics: Administration, Oral; Aluminum Hydroxide; Antacids; Anti-Infective Agents; Biological Availability; Cations; Ciprofloxacin; Drug Administration Schedule; Drug Combinations; Drug Interactions; Fluoroquinolones; Gatifloxacin; Humans; Intestinal Absorption; Magnesium Hydroxide; Models, Biological; Norfloxacin; Reference Values; Sucralfate

2007
The first steps towards fluoroquinolone resistance in Hungarian pneumococci.
    Journal of chemotherapy (Florence, Italy), 2006, Volume: 18, Issue:6

    Topics: Anti-Bacterial Agents; Aza Compounds; Bacterial Proteins; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Hungary; Microbial Sensitivity Tests; Moxifloxacin; Mutation, Missense; Ofloxacin; Pneumococcal Infections; Quinolines; Streptococcus pneumoniae

2006
Antimicrobial efficacy of gatifloxacin and moxifloxacin with and without benzalkonium chloride compared with ciprofloxacin and levofloxacin against methicillin-resistant Staphylococcus aureus.
    Journal of chemotherapy (Florence, Italy), 2007, Volume: 19, Issue:2

    Topics: Anti-Infective Agents; Aza Compounds; Benzalkonium Compounds; Cells, Cultured; Ciprofloxacin; Drug Combinations; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Preservatives, Pharmaceutical; Quinolines; Staphylococcus aureus

2007
Comparative minimal inhibitory and mutant prevention drug concentrations of four fluoroquinolones against ocular isolates of Haemophilus influenzae.
    Eye & contact lens, 2007, Volume: 33, Issue:3

    Topics: Anti-Infective Agents; Antimutagenic Agents; Aza Compounds; Ciprofloxacin; Dose-Response Relationship, Drug; Eye; Fluoroquinolones; Gatifloxacin; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Osmolar Concentration; Quinolines

2007
Zymar (Gatifloxacin 0.3%) shows excellent Gram-negative activity against Serratia marcescens and Pseudomonas aeruginosa in a New Zealand White rabbit keratitis model.
    Cornea, 2007, Volume: 26, Issue:5

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Corneal Ulcer; Disease Models, Animal; Eye Infections, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Serratia Infections; Serratia marcescens; Tobramycin

2007
The inhibitory effects of fluoroquinolones on L-carnitine transport in placental cell line BeWo.
    International journal of pharmaceutics, 2008, Mar-03, Volume: 351, Issue:1-2

    Topics: Biological Transport; Carnitine; Cell Line, Tumor; Ciprofloxacin; Drug Interactions; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Ofloxacin; Organic Cation Transport Proteins; Piperazines; Placenta; Sodium; Solute Carrier Family 22 Member 5

2008
Intrinsic cytotoxic effects of fluoroquinolones on human corneal keratocytes and endothelial cells.
    Current medical research and opinion, 2008, Volume: 24, Issue:2

    Topics: Anti-Bacterial Agents; Aza Compounds; Biological Assay; Ciprofloxacin; Cornea; Corneal Stroma; Endothelial Cells; Endothelium, Corneal; Fluoroquinolones; Gatifloxacin; Humans; In Vitro Techniques; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines

2008
[Resistance profiles to fluoroquinolones in clinical isolates of Gram positive cocci].
    Biomedica : revista del Instituto Nacional de Salud, 2008, Volume: 28, Issue:2

    Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Colombia; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Enterococcus; Fluoroquinolones; Gatifloxacin; Humans; Moxifloxacin; Quinolines; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae

2008
Third- and fourth-generation fluoroquinolones: retrospective comparison of endophthalmitis after cataract surgery performed over 10 years.
    Journal of cataract and refractive surgery, 2008, Volume: 34, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Aza Compounds; Ciprofloxacin; Cross-Sectional Studies; Endophthalmitis; Eye Infections, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Humans; Male; Middle Aged; Moxifloxacin; Ofloxacin; Phacoemulsification; Postoperative Complications; Prevalence; Quinolines; Retrospective Studies

2008
Evaluation of toxicity of commercial ophthalmic fluoroquinolone antibiotics as assessed on immortalized corneal and conjunctival epithelial cells.
    Cornea, 2008, Volume: 27, Issue:8

    Topics: Anti-Infective Agents; Aza Compounds; Cell Line; Cell Survival; Ciprofloxacin; Conjunctiva; Drug Evaluation, Preclinical; Epithelial Cells; Epithelium, Corneal; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Ophthalmic Solutions; Quinolines; Tetrazolium Salts; Thiazoles

2008
[Analysis on susceptibility of ocular bacterial pathogens to four kinds of fluoroquinolone].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2008, Volume: 44, Issue:3

    Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Eye; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin

2008
Biofilm formation is not necessary for development of quinolone-resistant "persister" cells in an attached Staphylococcus epidermidis population.
    The International journal of artificial organs, 2008, Volume: 31, Issue:9

    Topics: Anti-Infective Agents; Aza Compounds; Bacterial Adhesion; Biofilms; Ciprofloxacin; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Naphthyridines; Prosthesis-Related Infections; Quinolines; Quinolones; Staphylococcal Infections; Staphylococcus epidermidis

2008
grlA and gyrA mutations and antimicrobial susceptibility in clinical isolates of ciprofloxacin- methicillin-resistant Staphylococcus aureus.
    European journal of medical research, 2008, Aug-18, Volume: 13, Issue:8

    Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Electrophoresis, Agar Gel; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Gatifloxacin; Gene Expression Regulation, Bacterial; Methicillin Resistance; Mutation; Polymerase Chain Reaction; Quinolones; Staphylococcus aureus; Trans-Activators

2008
Determination of the inhibitory potential of 6 fluoroquinolones on CYP1A2 and CYP2C9 in human liver microsomes.
    Acta pharmacologica Sinica, 2008, Volume: 29, Issue:12

    Topics: Animals; Anti-Infective Agents; Aryl Hydrocarbon Hydroxylases; Aza Compounds; Ciprofloxacin; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9; Fluoroquinolones; Gatifloxacin; Humans; Isoenzymes; Levofloxacin; Microsomes, Liver; Molecular Structure; Moxifloxacin; Ofloxacin; Quinolines; Reproducibility of Results

2008
The resistance patterns of normal ocular bacterial flora to 4 fluoroquinolone antibiotics.
    Cornea, 2009, Volume: 28, Issue:1

    Topics: Anti-Bacterial Agents; Aza Compounds; Bacteria; Bacteria, Aerobic; Ciprofloxacin; Conjunctiva; Eye; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines

2009
Fluoroquinolones and postoperative endophthalmitis.
    Journal of cataract and refractive surgery, 2009, Volume: 35, Issue:2

    Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Aza Compounds; Ciprofloxacin; Endophthalmitis; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Moxifloxacin; Ofloxacin; Phacoemulsification; Postoperative Complications; Prevalence; Quinolines

2009
Fluoroquinolones and postoperative endophthalmitis.
    Journal of cataract and refractive surgery, 2009, Volume: 35, Issue:2

    Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Aza Compounds; Ciprofloxacin; Endophthalmitis; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Moxifloxacin; Ofloxacin; Phacoemulsification; Postoperative Complications; Prevalence; Quinolines

2009
Comparison of in vitro susceptibilities of Gram-positive cocci isolated from ocular infections against the second and fourth generation quinolones at a tertiary eye care centre in South India.
    Eye (London, England), 2010, Volume: 24, Issue:1

    Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Eye Infections, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacterial Infections; Humans; India; Male; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Retrospective Studies; Staphylococcus; Streptococcus

2010
The effect of fluoroquinolone antibiotics on growing cartilage in the lamb model.
    Journal of pediatric orthopedics, 2009, Volume: 29, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Cartilage, Articular; Child; Chromatography, High Pressure Liquid; Ciprofloxacin; Dose-Response Relationship, Drug; Fluorescent Dyes; Fluoroquinolones; Gatifloxacin; Growth Plate; Humans; Male; Models, Animal; Sheep; Tibia

2009
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents.
    Drug metabolism and pharmacokinetics, 2009, Volume: 24, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Diclofenac; Dioxolanes; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Phenylacetates; Piperazines; Receptors, GABA-A; Seizures

2009
Comparison of fluoroquinolones: cytotoxicity on human corneal epithelial cells.
    Eye (London, England), 2010, Volume: 24, Issue:5

    Topics: Anti-Infective Agents; Aza Compounds; Cell Survival; Cells, Cultured; Ciprofloxacin; Electric Impedance; Epithelial Cells; Epithelium, Corneal; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Moxifloxacin; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Preservatives, Pharmaceutical; Quinolines

2010
A comparative analysis of chromosomal aberrations in cultured human lymphocytes due to fluoroquinolone drugs at different expression periods.
    Archives of toxicology, 2010, Volume: 84, Issue:5

    Topics: Anti-Infective Agents; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Ciprofloxacin; DNA Replication; Dose-Response Relationship, Drug; Fluoroquinolones; Gatifloxacin; Humans; Lymphocytes; Ofloxacin

2010
Synthesis and antitubercular evaluation of new fluoroquinolone derivatives coupled with carbohydrates.
    Carbohydrate research, 2010, Apr-19, Volume: 345, Issue:6

    Topics: Antitubercular Agents; Aza Compounds; Carbohydrates; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Moxifloxacin; Mycobacterium tuberculosis; Quinolines

2010
[Antimicrobial susceptibility patterns of Legionella isolates in the environment and in patients].
    The Korean journal of laboratory medicine, 2010, Volume: 30, Issue:1

    Topics: Anti-Bacterial Agents; Azithromycin; Ciprofloxacin; Clarithromycin; Clindamycin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Legionella; Legionellosis; Microbial Sensitivity Tests; Naphthyridines

2010
[Prevalence of Clostridium difficile in the gastrointestinal tract of hospitalized children under two years of age].
    Medycyna doswiadczalna i mikrobiologia, 2010, Volume: 62, Issue:1

    Topics: Aza Compounds; Ciprofloxacin; Clindamycin; Clostridioides difficile; Drug Resistance, Multiple, Bacterial; Erythromycin; Feces; Female; Fluoroquinolones; Gastrointestinal Tract; Gatifloxacin; Genotype; Humans; Infant; Infant, Newborn; Male; Metronidazole; Moxifloxacin; Phenotype; Quinolines; Species Specificity; Vancomycin

2010
Topical fluoroquinolone use as a risk factor for in vitro fluoroquinolone resistance in ocular cultures.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2011, Volume: 129, Issue:4

    Topics: Administration, Topical; Aged; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; Drug Resistance, Multiple, Bacterial; Eye Infections, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Humans; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Quinolines; Risk Factors; Staphylococcal Infections; Staphylococcus aureus

2011
Susceptibility of Streptococcus pneumoniae to fluoroquinolones in Canada.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:8

    Topics: Anti-Bacterial Agents; Aza Compounds; Binding Sites; Canada; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Pneumococcal Infections; Quinolines; Streptococcus pneumoniae

2011
[In vitro antibiotic susceptibility to fluoroquinolones].
    Archivos de la Sociedad Espanola de Oftalmologia, 2012, Volume: 87, Issue:3

    Topics: Acanthamoeba Keratitis; Anti-Bacterial Agents; Aza Compounds; Body Fluids; Ciprofloxacin; Colombia; Conjunctivitis, Bacterial; Drug Resistance, Multiple, Bacterial; Eye Infections, Bacterial; Eye Infections, Fungal; Eye Infections, Parasitic; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Keratitis; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Retrospective Studies

2012
Induction of mycobacterial resistance to quinolone class antimicrobials.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:7

    Topics: Anti-Infective Agents; Antitubercular Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Molecular Structure; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines

2012
Aluminium sensitized spectrofluorimetric determination of fluoroquinolones in milk samples coupled with salting-out assisted liquid-liquid ultrasonic extraction.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 96

    Topics: Acetonitriles; Aluminum; Ammonium Sulfate; Animals; Cattle; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Hydrogen-Ion Concentration; Limit of Detection; Liquid-Liquid Extraction; Milk; Norfloxacin; Ofloxacin; Solutions; Spectrometry, Fluorescence; Temperature; Ultrasonics; Water

2012
Effect of fluoroquinolone resistance selection on the fitness of three strains of Clostridium perfringens.
    Microbial drug resistance (Larchmont, N.Y.), 2013, Volume: 19, Issue:6

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Clostridium perfringens; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Genetic Fitness; Microbial Sensitivity Tests; Microbial Viability; Mutation; Norfloxacin

2013
Fluoroquinolone susceptibility in Mycobacterium tuberculosis after pre-diagnosis exposure to older- versus newer-generation fluoroquinolones.
    International journal of antimicrobial agents, 2013, Volume: 42, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Aza Compounds; Case-Control Studies; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Tuberculosis

2013
Spectrum of bacterial keratitis at a tertiary eye care centre in India.
    BioMed research international, 2013, Volume: 2013

    Topics: Aza Compounds; Ciprofloxacin; Corneal Ulcer; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Humans; India; Microbial Sensitivity Tests; Moxifloxacin; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus

2013
Tracking the establishment of local endemic populations of an emergent enteric pathogen.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Oct-22, Volume: 110, Issue:43

    Topics: Anti-Bacterial Agents; Child; Child, Preschool; Chromosomes, Bacterial; Ciprofloxacin; Dysentery, Bacillary; Endemic Diseases; Evolution, Molecular; Fluoroquinolones; Gatifloxacin; Genetic Variation; Genome, Bacterial; Genomics; Geography; Humans; Infant; Molecular Sequence Data; Mutation Rate; Phylogeny; Sequence Analysis, DNA; Shigella sonnei; Vietnam

2013
Effect of fluoroquinolones on mitochondrial function in pancreatic beta cells.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Feb-14, Volume: 52

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Aza Compounds; Cells, Cultured; Ciprofloxacin; Flavin-Adenine Dinucleotide; Fluoroquinolones; Gatifloxacin; Glucose; Insulin-Secreting Cells; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Mitochondria; Moxifloxacin; NADP; Quinolines; Sulfonylurea Receptors

2014
Experimental and theoretical studies on the molecular properties of ciprofloxacin, norfloxacin, pefloxacin, sparfloxacin, and gatifloxacin in determining bioavailability.
    Journal of biological physics, 2014, Volume: 40, Issue:4

    Topics: Biological Availability; Buffers; Ciprofloxacin; Fluoroquinolones; Gastrointestinal Absorption; Gatifloxacin; Hydrogen-Ion Concentration; Models, Molecular; Molecular Conformation; Norfloxacin; Octanols; Pefloxacin; Phosphates; Solvents; Static Electricity; Thermodynamics

2014
Molecularly imprinted polymers for the solid-phase extraction of four fluoroquilones from milk and lake water samples.
    Journal of separation science, 2015, Volume: 38, Issue:20

    Topics: Animals; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Gatifloxacin; Lakes; Levofloxacin; Milk; Molecular Imprinting; Polymethyl Methacrylate; Solid Phase Extraction; Water Pollutants, Chemical

2015
Patterns of Multi-Antibiotic-Resistant Escherichia Coli from Streams with No History of Antimicrobial Inputs.
    Microbial ecology, 2016, Volume: 72, Issue:4

    Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactams; Ciprofloxacin; Drug Combinations; Drug Resistance, Multiple, Bacterial; Escherichia coli; Fluoroquinolones; Gatifloxacin; Geologic Sediments; Microbial Sensitivity Tests; Rivers; Water Microbiology

2016
In Vitro Resistance Development to Nemonoxacin in Streptococcus pneumoniae: A Unique Profile for a Novel Nonfluorinated Quinolone.
    Microbial drug resistance (Larchmont, N.Y.), 2016, Volume: 22, Issue:7

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Culture Media; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gene Expression; Microbial Sensitivity Tests; Mutation; Quinolones; Sequence Analysis, DNA; Streptococcus pneumoniae; Structure-Activity Relationship

2016
Role of gyrB Mutations in Pre-extensively and Extensively Drug-Resistant Tuberculosis in Thai Clinical Isolates.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:9

    Topics: Aminopyridines; Antitubercular Agents; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Gatifloxacin; Gene Expression; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Thailand; Tuberculosis, Pulmonary

2016
Biophysical control of the growth of Agrobacterium tumefaciens using extremely low frequency electromagnetic waves at resonance frequency.
    Biochemical and biophysical research communications, 2017, 12-09, Volume: 494, Issue:1-2

    Topics: Agrobacterium tumefaciens; Amikacin; Anti-Bacterial Agents; Carbenicillin; Cefaclor; Chloramphenicol; Ciprofloxacin; DNA, Bacterial; Electromagnetic Radiation; Fluoroquinolones; Gatifloxacin; Gentamicins; Plant Tumors; Rifampin; Solanum lycopersicum

2017
Effectiveness of treatment regimens for Typhoid fever in the nalidixic acid-resistant S. typhi (NARST) era in South India.
    Tropical doctor, 2018, Volume: 48, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Ciprofloxacin; Cohort Studies; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Hospitalization; Humans; India; Male; Microbial Sensitivity Tests; Nalidixic Acid; Recurrence; Salmonella typhi; Treatment Outcome; Typhoid Fever; Young Adult

2018
The cardiovascular toxicity induced by high doses of gatifloxacin and ciprofloxacin in zebrafish.
    Environmental pollution (Barking, Essex : 1987), 2019, Volume: 254, Issue:Pt B

    Topics: Animals; Anti-Bacterial Agents; Cardiovascular Physiological Phenomena; Cardiovascular System; Ciprofloxacin; Down-Regulation; Gatifloxacin; Heart Rate; Humans; Models, Animal; Myocardial Contraction; Water Pollutants, Chemical; Zebrafish

2019
Corynebacterium Keratitis: Pure Versus Mixed Infection and Antibiotic Susceptibility Patterns From Different Tertiary Eye Care Centers.
    Cornea, 2022, Nov-01, Volume: 41, Issue:11

    Topics: Anti-Bacterial Agents; Cefazolin; Ciprofloxacin; Coinfection; Corynebacterium; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Keratitis; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Retrospective Studies; Tertiary Care Centers; Vancomycin

2022
Association between initiation of fluoroquinolones and hospital admission or emergency department visit for suicidality: population based cohort study.
    BMJ (Clinical research ed.), 2022, 10-04, Volume: 379

    Topics: Adult; Anti-Bacterial Agents; Azithromycin; Ciprofloxacin; Cohort Studies; Emergency Service, Hospital; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Hospitals; Humans; Levofloxacin; Moxifloxacin; Norfloxacin; Retrospective Studies; Suicidal Ideation; Suicide; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections

2022
Fluoroquinolone resistance in bacterial isolates from ocular infections: Trend in antibiotic susceptibility patterns between 2005-2020.
    Indian journal of ophthalmology, 2022, Volume: 70, Issue:12

    Topics: Anti-Bacterial Agents; Cefuroxime; Ciprofloxacin; Colistin; Eye Infections; Fluoroquinolones; Gatifloxacin; Humans; Longitudinal Studies; Moxifloxacin; Ofloxacin; Retrospective Studies

2022