ciprofloxacin and fluorouracil

ciprofloxacin has been researched along with fluorouracil in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.13)18.2507
2000's8 (25.00)29.6817
2010's20 (62.50)24.3611
2020's3 (9.38)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Dahiya, R; Pathak, D1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Abdel-Wahab, BF; Awad, GE; Badria, FA1
Doma, MR; Jada, S; Khan, IA; Kumar, HM; Kumar, S; Malik, F; Qazi, GN; Sharma, A; Singh, PP1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Hamid, A; Jaglan, S; Klapötke, TM; Kumar, D; Narasimhan, B; Qazi, AK; Singh, K; Stierstorfer, J; Verma, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chanu, MB; Mahendra, M; Puttaraju, KB; Rai, K; Rasal, VP; Shivashankar, K; Venkata Vivek, PN1
Ganesh Kumar, C; Malla Reddy, G; Nagender, P; Naresh Kumar, R; Narsaiah, B; Poornachandra, Y1
Antoszczak, M; Celewicz, L; Huczyński, A; Janczak, J; Kleczewska, N; Lewandowska, M; Maj, E; Stefańska, J; Wietrzyk, J1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Al-Rashood, ST; El-Messery, SM; El-Subbagh, HI; Habib, EE; Hassan, GS; Nagi, MN1
G, JD; Ganesh Kumar, C; Krishna Swaroop, D; Nanubolu, JB; Naresh Kumar, R; Narsaiah, B; Poornachandra, Y; Ranjithreddy, P; Ratnakar Reddy, K; Ravikumar, N; Shravan Kumar, G1
Ashenden, S; Bender, A; Cokol, M; Karakoc, I; Kuru, N; Mason, DJ; Meral, S; Stott, I; Weinstein, ZB1
Bernardino, AMR; Boechat, N; Dos Santos, MS; Faria, JV; Miguita, AGC; Vegi, PF1
Gao, F; Wang, T; Xiao, J; Zhang, X1
Capito, JE; El-Manawaty, MA; George, RF; Girgis, AS; Panda, SS; Salman, A; Samir, A; Thomas, SJ1
Dinh Thanh, N; Minh Tri, N; Ngoc Toan, V; Thi Thu Huong, N1
Lacey, E; Piggott, MJ; Pullella, GA; Vuong, D1
de Vries, EG; Hospers, GA; Mulder, NH; Schröder, CP; Sleijfer, DT; van der Graaf, WT; Willemse, PH1
Ljungberg, B; Nilsson-Ehle, I; Nyhlén, A; Odenholt, I1
Gowda, RV; Stout, R1
Bourikas, LA; Drygiannakis, I; Klironomos, S; Kolios, G; Kouroumalis, E; Manousou, P; Mouzas, IA; Notas, G; Pelagiadis, I; Valatas, V1
Anami, S; Fujii, C; Kitada, N; Kondoh, M; Minegaki, T; Morita, S; Nishino, M; Takara, K; Watari, M; Yasuda, J1
Chakraborty, A; Gloriani, NG; Miyahara, S; Villanueva, SY; Yoshida, S1
Abo-Riya, M; Infante, MR; Manresa, MA; Muzzalupo, R; Pérez, L; Pinazo, A; Tavano, L1
Affek, A; Affek, K; Doskocz, N; Załęska-Radziwiłł, M1

Reviews

3 review(s) available for ciprofloxacin and fluorouracil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Recently reported biological activities of pyrazole compounds.
    Bioorganic & medicinal chemistry, 2017, 11-01, Volume: 25, Issue:21

    Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Pyrazoles

2017
Quinolone hybrids and their anti-cancer activities: An overview.
    European journal of medicinal chemistry, 2019, Mar-01, Volume: 165

    Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Quinolones; Structure-Activity Relationship

2019

Trials

2 trial(s) available for ciprofloxacin and fluorouracil

ArticleYear
Prevention of febrile leucopenia after chemotherapy in high-risk breast cancer patients: no significant difference between granulocyte-colony stimulating growth factor or ciprofloxacin plus amphotericin B.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:5

    Topics: Adult; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ciprofloxacin; Costs and Cost Analysis; Cyclophosphamide; Drug Therapy, Combination; Epirubicin; Female; Fever; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Length of Stay; Leukopenia; Methotrexate; Middle Aged; Neoplasm Metastasis; Netherlands; Prospective Studies; Recombinant Proteins

1999
[Equalization of breast cancer chemotherapy at general hospital( II )-evaluation of safety in FEC and TC regimens].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Breast Neoplasms; Ciprofloxacin; Cyclophosphamide; Docetaxel; Epirubicin; Female; Fluorouracil; Hospitals, General; Humans; Japan; Middle Aged; Neutropenia; Taxoids

2009

Other Studies

27 other study(ies) available for ciprofloxacin and fluorouracil

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Synthetic studies on novel benzimidazolopeptides with antimicrobial, cytotoxic and anthelmintic potential.
    European journal of medicinal chemistry, 2007, Volume: 42, Issue:6

    Topics: Animals; Anthelmintics; Anti-Infective Agents; Antineoplastic Agents; Bacteria; Cell Line, Tumor; Cytotoxins; Fungi; Humans; Oligochaeta; Peptides; Protein Conformation

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Synthesis, antimicrobial, antioxidant, anti-hemolytic and cytotoxic evaluation of new imidazole-based heterocycles.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antioxidants; Bacteria; Cell Proliferation; Drug Screening Assays, Antitumor; Erythrocytes; Hemolysis; Heterocyclic Compounds; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Rats; Stereoisomerism; Structure-Activity Relationship

2011
Design and synthesis of novel magnolol derivatives as potential antimicrobial and antiproliferative compounds.
    European journal of medicinal chemistry, 2012, Volume: 51

    Topics: Anti-Infective Agents; Antifungal Agents; Antineoplastic Agents; Bacteria; Biological Products; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; DNA Fragmentation; Drug Design; Humans; Lignans

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Synthesis, antimicrobial and cytotoxicity study of 1,3-disubstituted-1H-naphtho[1,2-e][1,3]oxazines.
    European journal of medicinal chemistry, 2012, Volume: 56

    Topics: Anti-Bacterial Agents; Antifungal Agents; Aspergillus niger; Candida albicans; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Microwave assisted synthesis of dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4-ones; synthesis, in vitro antimicrobial and anticancer activities of novel coumarin substituted dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4-ones.
    European journal of medicinal chemistry, 2013, Volume: 69

    Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Bacteria; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Coumarins; Drug Screening Assays, Antitumor; Fungi; Humans; Microbial Sensitivity Tests; Microwaves; Models, Molecular; Molecular Structure; Pyrimidinones

2013
Synthesis, cytotoxicity, antimicrobial and anti-biofilm activities of novel pyrazolo[3,4-b]pyridine and pyrimidine functionalized 1,2,3-triazole derivatives.
    Bioorganic & medicinal chemistry letters, 2014, Jul-01, Volume: 24, Issue:13

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bacteria; Biofilms; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; MCF-7 Cells; Microbial Sensitivity Tests; Molecular Structure; Pyrazoles; Pyridines; Pyrimidines; Structure-Activity Relationship; Triazoles

2014
Synthesis and biological activity of salinomycin conjugates with floxuridine.
    European journal of medicinal chemistry, 2015, Mar-26, Volume: 93

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Floxuridine; Humans; Methicillin-Resistant Staphylococcus aureus; Molecular Structure; Pyrans; Staphylococcus epidermidis; Structure-Activity Relationship

2015
Synthesis, biological evaluation and molecular modeling study of some new methoxylated 2-benzylthio-quinazoline-4(3H)-ones as nonclassical antifolates.
    Bioorganic & medicinal chemistry letters, 2016, 10-01, Volume: 26, Issue:19

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Inhibitory Concentration 50; Microbial Sensitivity Tests; Models, Molecular; Quinazolines

2016
Synthesis of novel pyrazolo[3,4-b]quinolinyl acetamide analogs, their evaluation for antimicrobial and anticancer activities, validation by molecular modeling and CoMFA analysis.
    European journal of medicinal chemistry, 2017, Apr-21, Volume: 130

    Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Biofilms; Cell Line, Tumor; Humans; Microbial Sensitivity Tests; Models, Molecular; Pyrazoles; Quinolines; Structure-Activity Relationship

2017
Prediction of Antibiotic Interactions Using Descriptors Derived from Molecular Structure.
    Journal of medicinal chemistry, 2017, 05-11, Volume: 60, Issue:9

    Topics: Anti-Bacterial Agents; Drug Interactions; Molecular Structure

2017
Synthesis, pharmacological profile and 2D-QSAR studies of curcumin-amino acid conjugates as potential drug candidates.
    European journal of medicinal chemistry, 2020, Jun-15, Volume: 196

    Topics: Amino Acids; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Carrageenan; Cell Proliferation; Curcumin; Dose-Response Relationship, Drug; Edema; Mice; Microbial Sensitivity Tests; Molecular Structure; Pain; Pseudomonas aeruginosa; Quantitative Structure-Activity Relationship; Rats; Salmonella typhi; Spleen; Staphylococcus aureus; Streptococcus pyogenes; Ulcer

2020
Synthesis and biological screening of thiosemicarbazones of substituted 3-acetylcoumarins having d-glucose moiety.
    Bioorganic & medicinal chemistry letters, 2020, 12-15, Volume: 30, Issue:24

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Bacteria; Bacterial Infections; Coumarins; Fungi; Glucose; Humans; Microbial Sensitivity Tests; Mycoses; Structure-Activity Relationship; Thiosemicarbazones

2020
Total Synthesis of the Antitumor-Antitubercular 2,6'-Bijuglone Natural Product Diospyrin and Its 3,6'-Isomer.
    Journal of natural products, 2020, 12-24, Volume: 83, Issue:12

    Topics: Antineoplastic Agents; Antitubercular Agents; Isomerism; Naphthoquinones

2020
Postantibiotic effect of meropenem and ciprofloxacin in the presence of 5-fluorouracil.
    Chemotherapy, 2002, Volume: 48, Issue:4

    Topics: Anti-Infective Agents; Antimetabolites, Antineoplastic; Ciprofloxacin; Drug Interactions; Fluorouracil; Meropenem; Microbial Sensitivity Tests; Staphylococcus epidermidis; Thienamycins

2002
Pasteurella multocida infection in a post-chemotherapy neutropenic host following cat exposure.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2002, Volume: 14, Issue:6

    Topics: Aged; Animals; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cat Diseases; Cats; Ciprofloxacin; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neutropenia; Pasteurella Infections; Pasteurella multocida

2002
Ciprofloxacin decreases survival in HT-29 cells via the induction of TGF-beta1 secretion and enhances the anti-proliferative effect of 5-fluorouracil.
    British journal of pharmacology, 2009, Volume: 157, Issue:3

    Topics: Anti-Infective Agents; Antimetabolites, Antineoplastic; Caco-2 Cells; Cell Proliferation; Cell Survival; Ciprofloxacin; Colon; Drug Synergism; Fluorouracil; HT29 Cells; Humans; Immunologic Factors; Intestinal Mucosa; Transforming Growth Factor beta1

2009
In vitro sensitivity and resistance of 46 Leptospira strains isolated from rats in the Philippines to 14 antimicrobial agents.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12

    Topics: Amphotericin B; Ampicillin; Animals; Anti-Bacterial Agents; Cefotaxime; Ciprofloxacin; Doxycycline; Erythromycin; Fluorouracil; Fosfomycin; Leptospira; Microbial Sensitivity Tests; Neomycin; Philippines; Rats; Sulfamethoxazole; Trimethoprim; Vancomycin

2010
Cationic vesicles based on biocompatible diacyl glycerol-arginine surfactants: physicochemical properties, antimicrobial activity, encapsulation efficiency and drug release.
    Colloids and surfaces. B, Biointerfaces, 2014, Aug-01, Volume: 120

    Topics: Anti-Infective Agents; Arginine; Bacteria; Biocompatible Materials; Cations; Chemical Phenomena; Ciprofloxacin; Diglycerides; Drug Liberation; Fluorouracil; Hydrodynamics; Hydrogen-Ion Concentration; Liposomes; Microbial Sensitivity Tests; Particle Size; Static Electricity; Surface-Active Agents

2014
In vitro and in vivo genotoxicity assessment of selected pharmaceuticals in relation to Escherichia coli and Cyprinus carpio.
    Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 2016, Oct-14, Volume: 51, Issue:12

    Topics: Animals; Carps; Ciprofloxacin; Comet Assay; DNA Damage; Escherichia coli; Estradiol; Fluorouracil; Humans; In Vitro Techniques; Mutagenicity Tests; Mutagens

2016