ciprofloxacin has been researched along with difloxacin in 114 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (35.09) | 18.7374 |
| 1990's | 17 (14.91) | 18.2507 |
| 2000's | 37 (32.46) | 29.6817 |
| 2010's | 18 (15.79) | 24.3611 |
| 2020's | 2 (1.75) | 2.80 |
| Authors | Studies |
|---|---|
| Koga, H; Ohta, M | 1 |
| Domagala, JM; Heifetz, CL; Hutt, MP; Mich, TF; Nichols, JB; Solomon, M; Worth, DF | 1 |
| Chu, DT; Fernandes, PB; Maleczka, RE; Nordeen, CW; Pernet, AG | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Antón-Fos, GM; Duart, MJ; Mut-Ronda, S; Salabert-Salvador, MT | 1 |
| Chen, S; Cui, S; McDermott, PF; Meng, J; Paulsen, I; White, DG; Zhao, S | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Burkhardt, JE; Carlton, WW; Hill, MA | 1 |
| Corstvet, RE; Enright, FM; McBride, JW; McClure, JR; McDonough, KC; Paulsen, DB | 1 |
| Burkhardt, JE; Carlton, WW; Hill, MA; Turek, JJ | 1 |
| Pattyn, SR | 1 |
| Edstein, MD; Keeratithakul, D; Teja-Isavadharm, P; Watt, G; Webster, HK | 1 |
| Anderson, R; Joone, G; van Rensburg, CE | 2 |
| Bauer, JF; Elrod, L; Fornnarino, JR; Heathcote, DE; Krogh, SK; Linton, CL; Norris, BJ; Quick, JE | 1 |
| Burkhardt, JE; Carlton, WW; Hill, MA; Kesterson, JW | 1 |
| Benes, S; Cummings, M; Draft, K; McCormack, WM; Smith, BL | 1 |
| Allen, W; Gorzynski, EA; Gutman, SI | 1 |
| Chandrasekar, PH; Sluchak, JA | 1 |
| Dizon, M; Khan, MY; Kiel, FW | 1 |
| Ayers, LW; Barry, AL; Gavan, TL; Gerlach, EH; Jones, RN; Thornsberry, C | 1 |
| Smith, SM | 1 |
| Barry, AL; Jones, RN; Thornsberry, C | 1 |
| Bellin, EY; Chow, RT; Dougherty, TJ; Fraimow, HS; Miller, MH | 1 |
| Bailer, R; Chu, DT; Fernandes, PB; Hanson, CW; Stamm, JM; Vojtko, C | 1 |
| Liu, S; Meyer, RD | 1 |
| Fok, M; Gollapudi, SV; Gupta, S; Thadepalli, H; Vayuvegula, B | 1 |
| Michel, MF; Piot, P; Stolz, E; Tjiam, KH; van Klingeren, B; Wagenvoort, JH | 1 |
| Black, WA; Bowie, WR; Boyd, J; Chan, DG; Shaw, CE | 1 |
| Ballard, RC; Fehler, G; Koornhof, HJ; Liebowitz, LD; Saunders, J | 1 |
| Habiyaremye, I; Vandepitte, J; Verbist, L | 1 |
| Verbist, L | 1 |
| Fernandes, PB; Swanson, RN | 1 |
| Boscia, JA; Kaye, D; Kobasa, WD | 2 |
| Dibb, WL; Digranes, A | 1 |
| Deforges, L; Duval, J; Le Van Thoi, J; Soussy, CJ | 1 |
| Ackerman, VP; Fernandes, CJ; Wilson, RD | 1 |
| Bodey, GP; Ho, DH; LeBlanc, B; Rolston, KV | 2 |
| Bower, RR; Chu, DT; Fernandes, PB; Hanson, CW; Hardy, DJ; Hensey, DM; Ramer, NR; Swanson, RN | 1 |
| King, A; Phillips, I | 1 |
| Bower, RR; Chu, DT; Fernandes, PB; Jarvis, KP; Ramer, NR; Shipkowitz, N | 1 |
| Chuah, SK; Gollapudi, SV; Thadepalli, H | 1 |
| Hirschhorn, L; Neu, HC | 2 |
| Granneman, GR; Sennello, LT | 1 |
| Adams, KR; Mader, JT; Morrison, LT | 1 |
| Bansal, MB; Thadepalli, H | 1 |
| Donato, JB; Joseph, WS; LeFrock, JL; Smith, BR; Weber, SJ | 1 |
| Granneman, GR; Shu, VS; Snyder, KM | 1 |
| Chu, DT; Claiborne, AK; Fernandes, PB; Maleczka, RE; Nordeen, CW; Pernet, AG; Pihuleac, E | 1 |
| Eliopoulos, GM; Moellering, AE; Moellering, RC; Reiszner, E | 1 |
| Phillips, I; Power, EG | 1 |
| Burkhardt, JE; Carlton, WW; Hill, MA; Lamar, CH; Smith, GN | 1 |
| Gollapudi, S; Gupta, S; Kim, CH; Thadepalli, F | 1 |
| Abraham, MH; Mitchell, RC; Takács-Novák, K | 1 |
| Gesbert, F; Guittet, M; Kempf, I; van den Hoven, R | 1 |
| Endo, T; Inui, T; Matsushita, T; Taira, T | 1 |
| Barbosa, J; Barrón, D; Jiménez-Lozano, E | 1 |
| Ellis, R; Niedzielska, J; Posyniak, A; Semeniuk, S; Zmudzki, J | 1 |
| van den Hoven, R; Wagenaar, JA; Walker, RD | 1 |
| Herrick, RL; Olchowy, TW; TerHune, TN | 1 |
| Evans, EI; Frazier, DL; Thompson, L; Trettien, A | 1 |
| Buckley, SA; Holtzapple, CK; Stanker, LH | 1 |
| Carbone, M; De Sarro, A; Fera, MT; Giannone, M; Masucci, M; Pennisi, MG | 1 |
| Gilbert, J; Haber, M; Madafiglio, J; Marshall, GM; Norris, MD | 1 |
| Borrull, F; Calull, M; Hernández, M | 1 |
| Heinen, E | 1 |
| Bailac, S; Barbosa, J; Barrón, D; Jiménez-Lozano, E | 1 |
| Abd El-Aty, AM; Atef, M; el-Banna, HA; Goudah, A | 1 |
| Bregante, MA; Calvo, A; Garcia, MA; Hernandez, E; Puig, M; Rey, R; Solans, C | 1 |
| Nagaraju, V; Rao, RN | 1 |
| Abd El-Aty, AM; Goudah, A; Ismail, M; Shimoda, M | 1 |
| Fthenakis, GC; Mavrogianni, VS | 1 |
| Adams, AR; Brown, MP; Gronwall, R; Haines, GR; Merritt, K | 1 |
| Ayala, I; Cárceles, CM; Escudero, E; Fernández-Varón, E; Marín, P; Martos, N | 1 |
| Failing, K; Kaleta, EF; Theis, P | 1 |
| ismail, M | 1 |
| Cárceles, CM; Escudero, E; Fernández-Varón, E; Marín, P | 2 |
| Antonovich, VP; Duerkop, A; Karasyov, AA; Scripinets, YV; Wolfbeis, OS; Yegorova, AV | 1 |
| Darwish, AM; Freeman, DW; Schneider, MJ | 1 |
| Cárceles, CM; Fernández-varón, E; García-Martínez, JD; Marín, P; Montes, A; Sotillo, J; Vancraeynest, D | 1 |
| Cox, SK | 1 |
| Chen, X; Hua, H; Ji, C; Lin, X; Liu, Y; Tang, S; Yue, Z | 1 |
| Amiridis, GS; Fragkou, IA; Fthenakis, GC; Gougoulis, DA; Mavrogianni, VS | 1 |
| Chen, ZL; Ding, HZ; Huang, XH; Yang, GX; Zeng, ZL | 1 |
| Gerchman, I; Levisohn, S; Lysnyansky, I; Perk, S | 1 |
| Abo-El-Sooud, K; Goudah, A | 1 |
| Kusari, S; Lamshöft, M; Spiteller, M; Sukul, P; Zühlke, S | 1 |
| Butcher, P; Giles, K; Kaufmann, A; Maden, K; Uría, D; Widmer, M | 1 |
| Kusari, S; Lamshöft, M; Prabhakaran, D; Spiteller, M | 1 |
| Hu, K; Wang, XL; Yang, XL; Yu, LZ; Yu, WJ | 1 |
| Bohoyo Gil, D; Guiberteau Cabanillas, A; Martínez Cañas, MA; Rodríguez Cáceres, MI | 1 |
| Lamshöft, M; Maheswari, MA; Prabhakaran, D; Spiteller, M; Sukul, P; Zühlke, S | 1 |
| Lamshöft, M; Spiteller, M; Sukul, P; Zühlke, S | 1 |
| Galeano Díaz, T; Guiberteau Cabanillas, A; Martínez Cañas, MA; Rodríguez Cáceres, MI | 1 |
| Cárceles, CM; Escudero, E; Fernández-Varón, E; Marín, P; Ramírez, MJ | 2 |
| Anadón, A; Ares, I; Castellano, V; Gamboa, F; Martínez, M; Martínez, MA; Martínez-Larrañaga, MR; Ramos, E; Suárez, FH | 1 |
| Fu, GH; Hu, K; Yang, XL; Yu, WJ; Zhang, HX | 1 |
| Clemens, J; Dong, R; Guo, J; Ostermann, A; Siemens, J | 1 |
| Choi, MJ; Damte, D; Gebru, E; Kim, YH; Lee, SJ; Park, SC | 1 |
| Bellini, MS; Clavel, A; Lodi, A; Pijnenburg, N | 1 |
| Dube, S; Moema, D; Nindi, MM | 1 |
| Chang, ZQ; Gai, CL; Li, J; Li, JT; Sun, M; Zhao, FZ | 1 |
| Focks, A; Groeneweg, J; Heuer, H; Jechalke, S; Rosendahl, I; Siemens, J; Smalla, K | 1 |
| Companyó, R; Guiteras, J; Jiménez, V | 1 |
| Abo El-Ela, FI; El-Banna, HA; El-Gendy, AA; Radi, AM; Tohamy, MA | 1 |
| Hamscher, G; Janusch, F; Mohring, SA; Scherz, G | 1 |
| Albiol-Chiva, J; Carda-Broch, S; Esteve-Romero, J; Iborra-Millet, JJ; Peris-Vicente, J | 1 |
| Adimi, T; Bayat, F; Karimi, AR | 1 |
| Arterburn, JB; Azar, SR; Chinnasamy, R; Gass, JT; Hanley, KA; Rossi, SL; Scroggs, SLP; Vasilakis, N; Widen, SG | 1 |
7 trial(s) available for ciprofloxacin and difloxacin
| Article | Year |
|---|---|
Evaluation of difloxacin in the treatment of uncomplicated urethral gonorrhea in men.
Topics: Adult; Anti-Bacterial Agents; Chlamydia Infections; Ciprofloxacin; Clinical Trials as Topic; Fluoroquinolones; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillin G; Tetracycline | 1989 |
Comparison of fluoroquinolone pharmacokinetic parameters after treatment with marbofloxacin, enrofloxacin, and difloxacin in dogs.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Cross-Over Studies; Dogs; Enrofloxacin; Female; Fluoroquinolones; Quinolones; Skin | 2000 |
Activity and postantibiotic effect of marbofloxacin, enrofloxacin, difloxacin and ciprofloxacin against feline Bordetella bronchiseptica isolates.
Topics: Animals; Anti-Infective Agents; Bordetella bronchiseptica; Bordetella Infections; Cat Diseases; Cats; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Male; Microbial Sensitivity Tests; Quinolones | 2001 |
Efficacy of difloxacin against respiratory infections of lambs.
Topics: Animals; Animals, Newborn; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Injections, Subcutaneous; Mannheimia haemolytica; Pasteurellosis, Pneumonic; Sheep; Sheep Diseases; Treatment Outcome | 2005 |
Pharmacokinetics of difloxacin after intravenous, intramuscular, and intragastric administration to horses.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Ciprofloxacin; Creatine Kinase; Cross-Over Studies; Fluoroquinolones; Half-Life; Horses; Injections, Intramuscular; Injections, Intravenous | 2006 |
Disposition kinetics of difloxacin after intravenous, intramuscular and subcutaneous administration in calves.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Cattle; Ciprofloxacin; Cross-Over Studies; Female; Fluoroquinolones; Half-Life; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Male; Mannheimia haemolytica; Microbial Sensitivity Tests | 2007 |
Pharmacokinetics after intravenous, intramuscular and subcutaneous administration of difloxacin in sheep.
Topics: Animals; Anti-Bacterial Agents; Biological Availability; Ciprofloxacin; Cross-Over Studies; Female; Fluoroquinolones; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Sheep | 2007 |
107 other study(ies) available for ciprofloxacin and difloxacin
| Article | Year |
|---|---|
Three-dimensional structure-activity relationships and receptor mapping of N1-substituents of quinolone antibacterials.
Topics: 4-Quinolones; Anti-Infective Agents; Computer Simulation; Escherichia coli; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Molecular Structure; Receptors, Drug; Software; Structure-Activity Relationship | 1991 |
1-Substituted 7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8- difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids. New quantitative structure-activity relationships at N1 for the quinolone antibacterials.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Carboxylic Acids; Chemical Phenomena; Chemistry; Mice; Microbial Sensitivity Tests; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1988 |
Synthesis and structure-activity relationship of 1-aryl-6,8-difluoroquinolone antibacterial agents.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Female; Fluorine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Microbial Sensitivity Tests; Quinolines; Spectrophotometry, Infrared; Structure-Activity Relationship | 1987 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Search compounds with antimicrobial activity by applying molecular topology to selected quinolones.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Discriminant Analysis; Drug Design; Microbial Sensitivity Tests; Quantitative Structure-Activity Relationship; Quinolones | 2003 |
Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials.
Topics: Animals; Anti-Infective Agents; DNA Topoisomerases; Drug Resistance, Bacterial; Fluoroquinolones; Gene Targeting; Genes, Bacterial; Mutation; Salmonella Infections, Animal; Salmonella typhimurium | 2007 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Morphologic and biochemical changes in articular cartilages of immature beagle dogs dosed with difloxacin.
Topics: Animals; Anti-Infective Agents; Cartilage, Articular; Ciprofloxacin; Collagen; Dogs; Fluoroquinolones; Glycosaminoglycans; Hydroxyproline; Paraffin Embedding; Uronic Acids | 1992 |
Use of an indwelling bronchial catheter model of bovine pneumonic pasteurellosis for evaluation of therapeutic efficacy of various compounds.
Topics: Animals; Anti-Infective Agents; Antibodies, Bacterial; Body Temperature; Bronchoalveolar Lavage Fluid; Cattle; Cell Count; Ciprofloxacin; Colony Count, Microbial; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fluoroquinolones; Mannheimia haemolytica; Oxytetracycline; Pasteurellosis, Pneumonic | 1992 |
Ultrastructural changes in articular cartilages of immature beagle dogs dosed with difloxacin, a fluoroquinolone.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Cartilage, Articular; Ciprofloxacin; Dogs; Femur Head; Fluoroquinolones; Humerus; Microscopy, Electron; Mitochondria | 1992 |
Anti-Mycobacterium leprae activity of several quinolones studied in the mouse.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Leprosy; Mice; Mycobacterium leprae; Quinolones | 1991 |
Measurement of ciprofloxacin in human plasma, whole blood, and erythrocytes by high-performance liquid chromatography.
Topics: Adult; Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Erythrocytes; Fluoroquinolones; Humans; Malaria, Falciparum; Plasma; Reference Standards | 1991 |
Interactions of the oxygen-dependent antimicrobial system of the human neutrophil with difloxacin, ciprofloxacin, pefloxacin and fleroxacin in the intraphagocytic eradication of Staphylococcus aureus.
Topics: Anti-Infective Agents; Child; Child, Preschool; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Granulomatous Disease, Chronic; Humans; Neutrophils; Pefloxacin; Phagocytosis; Staphylococcus aureus | 1990 |
Determination of temafloxacin, sarafloxacin, and difloxacin in bulk drug and dosage forms by high-performance liquid chromatography.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Quinolones; Solubility; Spectrophotometry, Ultraviolet | 1990 |
Histologic and histochemical changes in articular cartilages of immature beagle dogs dosed with difloxacin, a fluoroquinolone.
Topics: Age Factors; Animals; Anti-Infective Agents; Bone and Bones; Cartilage, Articular; Chondroitin; Ciprofloxacin; Dogs; Female; Femur Head; Fluoroquinolones; Humerus; Male; Proteoglycans | 1990 |
An in vitro investigation of the intraphagocytic bioactivity of difloxacin, ciprofloxacin, pefloxacin and fleroxacin.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Phagocytes | 1989 |
Comparative antimycobacterial activities of difloxacin, temafloxacin, enoxacin, pefloxacin, reference fluoroquinolones, and a new macrolide, clarithromycin.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Clarithromycin; Enoxacin; Erythromycin; Fluoroquinolones; Microbial Sensitivity Tests; Mycobacterium; Pefloxacin; Quinolones | 1989 |
Newer agents against methicillin and/or gentamicin-resistant and -susceptible staphylococci.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Daptomycin; Drug Resistance, Microbial; Fluoroquinolones; Gentamicins; Humans; Methicillin; Microbial Sensitivity Tests; Penicillin Resistance; Peptides; Species Specificity; Staphylococcus aureus | 1989 |
Comparative in vitro activities of ofloxacin, difloxacin, ciprofloxacin, and other selected antimicrobial agents against Brucella melitensis.
Topics: Anti-Infective Agents; Brucella; Brucellosis; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin | 1989 |
In vitro activity of the aryl-fluoroquinolones A-56619 and A-56620 and evaluation of disk susceptibility tests.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Microbial Sensitivity Tests; Norfloxacin; Piperazines; Quinolines; Staphylococcus; Streptococcus | 1986 |
In vitro comparison of A-56619, A-56620, amifloxacin, ciprofloxacin, enoxacin, norfloxacin, and ofloxacin against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Methicillin; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Penicillin Resistance; Piperazines; Quinolines; Staphylococcus aureus | 1986 |
In vitro evaluation of A-56619 and A-56620, two new quinolones.
Topics: Anti-Bacterial Agents; Bacteria; Bacteria, Anaerobic; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Piperazines; Quinolines | 1986 |
Association between early inhibition of DNA synthesis and the MICs and MBCs of carboxyquinolone antimicrobial agents for wild-type and mutant [gyrA nfxB(ompF) acrA] Escherichia coli K-12.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Mutation; Norfloxacin | 1988 |
In vitro evaluation of A-56619 (difloxacin) and A-56620: new aryl-fluoroquinolones.
Topics: Anti-Infective Agents; Aztreonam; Bacteria; Cefotaxime; Ciprofloxacin; Drug Combinations; Enterobacteriaceae; Escherichia coli; Fluoroquinolones; Gentamicins; Haemophilus influenzae; Half-Life; Humans; Imipenem; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Penicillins; Piperacillin; Piperazines; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus; Streptococcus; Thienamycins | 1986 |
In vitro activity of aryl fluoroquinolones, Abbott 56619 and Abbott 56620, compared to ciprofloxacin, norfloxacin and beta-lactams versus multidrug-resistant Enterobacteriaceae and Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Microbial Sensitivity Tests; Norfloxacin; Pseudomonas aeruginosa | 1986 |
Aryl-fluoroquinolone derivatives A-56619 (difloxacin) and A-56620 inhibit mitogen-induced human mononuclear cell proliferation.
Topics: Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Fluoroquinolones; Humans; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Mitogens; Monocytes; Receptors, Immunologic; Receptors, Interleukin-2 | 1986 |
In vitro activity of the two new 4-quinolones A56619 and A56620 against Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma hominis, Ureaplasma urealyticum and Gardnerella vaginalis.
Topics: Anti-Bacterial Agents; Bacteria; Chlamydia trachomatis; Ciprofloxacin; Fluoroquinolones; Gardnerella vaginalis; Humans; Microbial Sensitivity Tests; Mycoplasma; Neisseria gonorrhoeae; Tetracycline; Ureaplasma | 1986 |
In vitro activity of difloxacin hydrochloride (A-56619), A-56620, and cefixime (CL 284,635; FK 027) against selected genital pathogens.
Topics: Anti-Bacterial Agents; Bacteria; Cefixime; Cefotaxime; Chlamydia trachomatis; Ciprofloxacin; Female; Fluoroquinolones; Gardnerella vaginalis; Genitalia; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae | 1986 |
In vitro activity of A-56619 (difloxacin), A-56620, and other new quinolone antimicrobial agents against genital pathogens.
Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Ciprofloxacin; Female; Fluoroquinolones; Gardnerella vaginalis; Genitalia; Haemophilus; Haemophilus ducreyi; Humans; Male; Microbial Sensitivity Tests; Mycoplasma; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Oxazines; Ureaplasma | 1986 |
[Comparative in vitro activity of 10 new 4-quinolones against enteropathogenic bacteria].
Topics: Anti-Bacterial Agents; Campylobacter fetus; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Salmonella; Shigella; Vibrio cholerae; Yersinia enterocolitica | 1987 |
Comparative in-vitro activity of Ro 23-6240, a new trifluorinated quinolone.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines | 1987 |
Correlation of in vitro activities of the fluoroquinolones to their in vivo efficacies.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1988 |
Comparison of difloxacin, enoxacin, and cefazolin for the treatment of experimental Staphylococcus aureus endocarditis.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Cefazolin; Ciprofloxacin; Endocarditis, Bacterial; Enoxacin; Female; Fluoroquinolones; Half-Life; Injections, Intramuscular; Naphthyridines; Rabbits; Staphylococcal Infections | 1988 |
In vitro activities of A-56619 (difloxacin) and A-56620, two aryl fluoroquinolones.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Culture Media; Fluoroquinolones; Gram-Negative Bacteria; Hydrogen-Ion Concentration; Microbial Sensitivity Tests | 1988 |
[In vitro antibacterial activity of 2 new quinolones: A 56619 (difloxacin) and A 56620. Comparison with pefloxacin, ofloxacin and ciprofloxacin].
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
In vitro activity of A-56619 and A-56620 against multi-resistant and routine clinical isolates.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Pseudomonas; Staphylococcus; Streptococcus | 1988 |
In vitro evaluation of difloxacin (A-56619), A-56620, and other 4-quinolones against isolates from cancer patients.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Neoplasms; Quinones; Sepsis | 1987 |
Comparative antibacterial activities of temafloxacin hydrochloride (A-62254) and two reference fluoroquinolones.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Female; Fluoroquinolones; Hydrogen-Ion Concentration; Mice; Microbial Sensitivity Tests; Pyelonephritis; Quinolines; Quinolones | 1987 |
The comparative in-vitro activity of eight newer quinolones and nalidixic acid.
Topics: Acinetobacter; Aeromonas; Anti-Bacterial Agents; Bacteria; Bacteria, Anaerobic; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fluoroquinolones; Gram-Positive Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Pefloxacin; Quinolines | 1986 |
In vitro evaluation of S-25930 and S-25932, two new quinolones, against aerobic gram-negative isolates from cancer patients.
Topics: Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gram-Negative Bacteria; Humans; Naphthyridines; Neoplasms; Quinolizines | 1987 |
Comparison of difloxacin, enoxacin, and cefoperazone for treatment of experimental Enterobacter aerogenes endocarditis.
Topics: Animals; Anti-Bacterial Agents; Cefoperazone; Ciprofloxacin; Endocarditis, Bacterial; Enoxacin; Enterobacter; Enterobacteriaceae Infections; Female; Fluoroquinolones; Naphthyridines; Rabbits | 1987 |
In vivo evaluation of A-56619 (difloxacin) and A-56620: new aryl-fluoroquinolones.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Enterobacteriaceae Infections; Escherichia coli Infections; Female; Fluoroquinolones; Half-Life; Immunosuppression Therapy; Klebsiella Infections; Mice; Norfloxacin; Piperazines; Proteus Infections; Pseudomonas Infections; Pyelonephritis; Quinolines; Salmonella Infections, Animal; Staphylococcal Infections; Streptococcal Infections | 1986 |
Therapeutic evaluation of difloxacin (A-56619) and A-56620 for experimentally induced Bacteroides fragilis-associated intra-abdominal abscess.
Topics: Abscess; Animals; Anti-Bacterial Agents; Ascitic Fluid; Bacteroides fragilis; Bacteroides Infections; Ciprofloxacin; Escherichia coli; Fluoroquinolones; Half-Life; Male; Microbial Sensitivity Tests; Rats; Rats, Inbred Strains | 1986 |
In vitro activity of two new aryl-fluoroquinolone antimicrobial agents, difloxacin (A-56619) and A-56620 compared to that of other antimicrobial agents.
Topics: Anti-Bacterial Agents; Bacteria; Bacteriological Techniques; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Quinolines; Tobramycin | 1987 |
High-performance liquid chromatographic procedures for the determination of difloxacin and its metabolites in biological matrices.
Topics: Anti-Infective Agents; Biotransformation; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Humans; Kinetics; Oxidation-Reduction; Ultrafiltration | 1987 |
Comparative evaluation of A-56619, A-56620, and nafcillin in the treatment of experimental Staphylococcus aureus osteomyelitis.
Topics: Animals; Anti-Bacterial Agents; Bone and Bones; Ciprofloxacin; Fluoroquinolones; Nafcillin; Osteomyelitis; Rabbits; Random Allocation; Staphylococcal Infections; Staphylococcus aureus; Tissue Distribution | 1987 |
Activity of difloxacin (A-56619) and A-56620 against clinical anaerobic bacteria in vitro.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Cefoxitin; Ciprofloxacin; Drug Synergism; Fluoroquinolones; Microbial Sensitivity Tests; Species Specificity | 1987 |
In vitro activity of A-56619 and A56620, two new aryl-fluoroquinolone antimicrobial agents.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Norfloxacin; Piperazines; Quinolines | 1986 |
Factors influencing the in vitro activity of two new aryl-fluoroquinolone antimicrobial agents, difloxacin (A-56619) and A-56620.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Magnesium; Piperazines; Quinolines | 1986 |
Difloxacin metabolism and pharmacokinetics in humans after single oral doses.
Topics: Administration, Oral; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Half-Life; Humans; Kidney; Kinetics; Metabolic Clearance Rate | 1986 |
Synthesis and structure-activity relationships of novel arylfluoroquinolone antibacterial agents.
Topics: Acinetobacter; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Chemical Phenomena; Chemistry; Ciprofloxacin; Enterobacter; Escherichia coli; Female; Fluorine; Fluoroquinolones; Klebsiella pneumoniae; Mice; Norfloxacin; Pefloxacin; Piperazines; Pseudomonas aeruginosa; Quinolines; Staphylococcus; Streptococcus; Structure-Activity Relationship | 1985 |
In vitro activities of the quinolone antimicrobial agents A-56619 and A-56620.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Piperazines; Pseudomonas aeruginosa; Quinolines; Time Factors | 1985 |
Correlation between umuC induction and Salmonella mutagenicity assay for quinolone antimicrobial agents.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; DNA-Directed DNA Polymerase; Enoxacin; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Gene Expression Regulation, Bacterial; Mutagenicity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Quinolones; Salmonella typhimurium; SOS Response, Genetics; Species Specificity | 1993 |
Effects of difloxacin on the metabolism of glycosaminoglycans and collagen in organ cultures of articular cartilage.
Topics: Animals; Anti-Infective Agents; Cartilage, Articular; Ciprofloxacin; Collagen; Dogs; Fluoroquinolones; Glycosaminoglycans; Organ Culture Techniques | 1993 |
Difloxacin reverses multidrug resistance in HL-60/AR cells that overexpress the multidrug resistance-related protein (MRP) gene.
Topics: Anti-Infective Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Ciprofloxacin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoroquinolones; Gene Expression; HL-60 Cells; Humans; Microscopy, Confocal; Quinolones; Vincristine | 1995 |
On the partition of ampholytes: application to blood-brain distribution.
Topics: Albendazole; Anti-Infective Agents; Blood-Brain Barrier; Buffers; Ciprofloxacin; Cyclohexanes; Fluoroquinolones; Hydrogen-Ion Concentration; Morphine; Niflumic Acid; Nitrazepam; Octanols; Pharmaceutical Preparations; Solubility; Structure-Activity Relationship; Sulfamethazine; Water | 1997 |
Efficacy of difloxacin in growing broiler chickens for the control of infection due to pathogenic Mycoplasma gallisepticum.
Topics: Animals; Anti-Infective Agents; Chickens; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Male; Mycoplasma; Mycoplasma Infections; Poultry Diseases; Quinolones | 1998 |
Pharmacokinetic properties and oral bioavailabilities of difloxacin in pig and chicken.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Biological Availability; Chickens; Ciprofloxacin; Fluoroquinolones; Half-Life; Injections, Intravenous; Kinetics; Swine | 1998 |
Electrophoretic behaviour of quinolones in capillary electrophoresis. Effect of pH and evaluation of ionization constants.
Topics: Anti-Infective Agents; Chemical Phenomena; Chemistry, Physical; Ciprofloxacin; Electrophoresis, Capillary; Fluoroquinolones; Hydrogen-Ion Concentration; Ions; Mathematics; Models, Chemical; Molecular Structure; Norfloxacin; Quinolones; Solutions; Water | 1999 |
Determination of fluoroquinolone residues in animal tissues by liquid chromatography.
Topics: Animals; Anti-Infective Agents; Cattle; Chromatography, Liquid; Ciprofloxacin; Drug Residues; Fluoroquinolones; Kidney; Liver; Muscles; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Swine | 1999 |
In vitro activity of difloxacin against canine bacterial isolates.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Fluoroquinolones; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Netherlands; United States | 2000 |
Efficacy of difloxacin in calves experimentally infected with Mannheimia haemolytica.
Topics: Animals; Anti-Infective Agents; Body Temperature; Cattle; Cattle Diseases; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Lung; Male; Mannheimia haemolytica; Pasteurella Infections; Quinolones; Random Allocation; Weight Gain | 2000 |
Determination of fluoroquinolones in serum using an on-line clean-up column coupled to high-performance immunoaffinity-reversed-phase liquid chromatography.
Topics: Animals; Anti-Infective Agents; Cattle; Chromatography, Affinity; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Immunochemistry; Molecular Structure; Quinolones | 2001 |
Reversal of multidrug resistance-associated protein-mediated drug resistance in cultured human neuroblastoma cells by the quinolone antibiotic difloxacin.
Topics: Adenocarcinoma; Anti-Infective Agents; Antimony Potassium Tartrate; ATP-Binding Cassette Transporters; Breast Neoplasms; Ciprofloxacin; Cisplatin; Daunorubicin; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoroquinolones; Gene Amplification; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neuroblastoma; Polymerase Chain Reaction; Substrate Specificity; Tumor Cells, Cultured; Vincristine | 2001 |
Using nonaqueous capillary electrophoresis to analyze several quinolones in pig kidney samples.
Topics: Animals; Anti-Infective Agents; Calibration; Ciprofloxacin; Electrophoresis, Capillary; Enrofloxacin; Fluoroquinolones; Kidney; Molecular Structure; Oxolinic Acid; Quinolizines; Quinolones; Swine | 2002 |
Comparative serum pharmacokinetics of the fluoroquinolones enrofloxacin, difloxacin, marbofloxacin, and orbifloxacin in dogs after single oral administration.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Cross-Over Studies; Dogs; Enrofloxacin; Female; Fluoroquinolones; Male; Microbial Sensitivity Tests; Quinolones | 2002 |
Determination of difloxacin and sarafloxacin in chicken muscle using solid-phase extraction and capillary electrophoresis.
Topics: Animals; Anti-Infective Agents; Chickens; Ciprofloxacin; Drug Residues; Electrophoresis, Capillary; Fluoroquinolones; Muscles; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2002 |
Pharmacokinetics of difloxacin in goats.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Goats; Half-Life; Injections, Intramuscular; Injections, Intravenous; Metabolic Clearance Rate | 2002 |
Determination of enrofloxacin and its primary metabolite, ciprofloxacin, in pig tissues. Application to residue studies.
Topics: Adipose Tissue; Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Residues; Enrofloxacin; Fluoroquinolones; Kidney; Liver; Male; Muscles; Quinolones; Reference Standards; Reproducibility of Results; Sus scrofa | 2005 |
Separation and determination of synthetic impurities of difloxacin by reversed-phase high-performance liquid chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Contamination; Fluoroquinolones | 2004 |
Disposition kinetics of difloxacin in rabbit after intravenous and intramuscular injection of Dicural.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Ciprofloxacin; Female; Fluoroquinolones; Half-Life; Injections, Intramuscular; Injections, Intravenous; Male; Rabbits; Tissue Distribution | 2005 |
Pharmacokinetics of difloxacin and its concentration in body fluids and endometrial tissues of mares after repeated intragastric administration.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Ascitic Fluid; Bacteria; Body Fluids; Ciprofloxacin; Endometrium; Female; Fluoroquinolones; Half-Life; Horses; Intestinal Absorption; Microbial Sensitivity Tests; Synovial Fluid; Tissue Distribution | 2005 |
Determination of the inhibitory concentration 50% (IC50) of four selected drugs (chlortetracycline, doxycycline, enrofloxacin and difloxacin) that reduce in vitro the multiplication of Chlamydophila psittaci.
Topics: Animals; Anti-Bacterial Agents; Bird Diseases; Birds; Cells, Cultured; Chlamydophila psittaci; Chlortetracycline; Ciprofloxacin; Dose-Response Relationship, Drug; Doxycycline; Enrofloxacin; Fluoroquinolones; Inhibitory Concentration 50; Microbial Sensitivity Tests; Psittacosis | 2006 |
Pharmacokinetics and milk penetration of difloxacin after intravenous, subcutaneous and intramuscular administration to lactating goats.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Cross-Over Studies; Female; Fluoroquinolones; Goats; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Lactation; Milk | 2007 |
Sensitive luminescent determination of DNA using the terbium(III)-difloxacin complex.
Topics: Ciprofloxacin; DNA; Fluorescent Dyes; Fluoroquinolones; Hydrogen-Ion Concentration; Luminescent Measurements; Osmolar Concentration; Terbium | 2007 |
Simultaneous multiresidue determination of tetracyclines and fluoroquinolones in catfish muscle using high performance liquid chromatography with fluorescence detection.
Topics: Animals; Catfishes; Chlortetracycline; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Residues; Enrofloxacin; Fluoroquinolones; Muscles; Oxytetracycline; Spectrometry, Fluorescence; Tetracyclines | 2007 |
Disposition kinetics and pharmacokinetics--pharmacodynamic integration of difloxacin against Staphylococcus aureus isolates from rabbits.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Cross-Over Studies; Fluoroquinolones; Injections, Intravenous; Injections, Subcutaneous; Rabbits; Staphylococcal Infections; Staphylococcus aureus | 2008 |
Allometric scaling of marbofloxacin, moxifloxacin, danofloxacin and difloxacin pharmacokinetics: a retrospective analysis.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Humans; Moxifloxacin; Quinolines; Quinolones; Retrospective Studies; Species Specificity | 2007 |
[Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry].
Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2007 |
Efficacy of difloxacin for the control of postpartum uterine infections of ewes.
Topics: Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Case-Control Studies; Ciprofloxacin; Escherichia coli Infections; Female; Fluoroquinolones; Pregnancy; Puerperal Disorders; Sheep; Sheep Diseases; Uterine Diseases | 2007 |
Pharmacokinetics of difloxacin in pigs and broilers following intravenous, intramuscular, and oral single-dose applications.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Area Under Curve; Biological Availability; Chickens; Ciprofloxacin; Half-Life; Injections, Intramuscular; Injections, Intravenous; Male; Metabolic Clearance Rate; Species Specificity; Swine; Tissue Distribution | 2008 |
In vitro susceptibilities to fluoroquinolones in current and archived Mycoplasma gallisepticum and Mycoplasma synoviae isolates from meat-type turkeys.
Topics: Animals; Anti-Bacterial Agents; Chickens; Ciprofloxacin; Drug Resistance, Bacterial; Enrofloxacin; Fluoroquinolones; Meat; Mycoplasma gallisepticum; Mycoplasma Infections; Mycoplasma synoviae; Poultry Diseases; Turkeys | 2008 |
Pharmacokinetics and intramuscular bioavailability of difloxacin in dromedary camels (Camelus dromedarius).
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Camelus; Ciprofloxacin; Injections, Intramuscular; Intestinal Absorption; Male | 2009 |
Metabolism and excretion kinetics of 14C-labeled and non-labeled difloxacin in pigs after oral administration, and antimicrobial activity of manure containing difloxacin and its metabolites.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Calibration; Carbon Radioisotopes; Ciprofloxacin; Environmental Pollutants; Male; Manure; Microbial Sensitivity Tests; Reference Standards; Swine | 2009 |
Are liquid chromatography/electrospray tandem quadrupole fragmentation ratios unequivocal confirmation criteria?
Topics: Animals; Anti-Bacterial Agents; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Food Contamination; Ions; Muscle, Skeletal; Oxolinic Acid; Pesticide Residues; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Veterinary Drugs | 2009 |
In vitro residual anti-bacterial activity of difloxacin, sarafloxacin and their photoproducts after photolysis in water.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Residues; Photolysis; Water Pollutants, Chemical | 2009 |
Effects of fish CYP inducers on difloxacin N-demethylation in kidney cell of Chinese idle (Ctenopharyngodon idellus).
Topics: Analysis of Variance; Animals; beta-Naphthoflavone; Biotransformation; Chromatography, High Pressure Liquid; Ciprofloxacin; Cyprinidae; Cytochrome P-450 CYP1A1; Drug Interactions; Enzyme Induction; Kidney; Kinetics; Molecular Structure | 2010 |
Quantification of danofloxacin and difloxacin in chicken tissues in the presence of sarafloxacin as interference.
Topics: Animals; Anti-Bacterial Agents; Chickens; Ciprofloxacin; Fluoroquinolones; Food Contamination; Muscles; Reproducibility of Results; Spectrometry, Fluorescence | 2009 |
Photolysis of difloxacin and sarafloxacin in aqueous systems.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Environmental Restoration and Remediation; Half-Life; Humic Substances; Hydrogen-Ion Concentration; Kinetics; Light; Photolysis; Water; Water Pollutants, Chemical | 2009 |
Behaviour of (14)C-sulfadiazine and (14)C-difloxacin during manure storage.
Topics: Anti-Bacterial Agents; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Ciprofloxacin; Manure; Sulfadiazine; Tandem Mass Spectrometry | 2010 |
Simultaneous determination of quinolones for veterinary use by high-performance liquid chromatography with electrochemical detection.
Topics: Animals; Calibration; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Electrochemical Techniques; Electrodes; Fluoroquinolones; Reference Standards; Regression Analysis; Rheology; Veterinary Drugs | 2010 |
Pharmacokinetic and milk penetration of a difloxacin long-acting poloxamer gel formulation with carboxy-methylcellulose in lactating goats.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Chromatography, High Pressure Liquid; Ciprofloxacin; Female; Gels; Goat Diseases; Goats; Half-Life; Injections, Subcutaneous; Lactation; Mastitis; Milk | 2011 |
Pharmacokinetics and milk penetration of difloxacin after a long-acting formulation for subcutaneous administration to lactating goats.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Female; Goats; Infusions, Intravenous; Infusions, Subcutaneous; Microbial Sensitivity Tests; Milk; Spain; Staphylococcus aureus | 2010 |
Plasma disposition and tissue depletion of difloxacin and its metabolite sarafloxacin in the food producing animals, chickens for fattening.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Bacteria; Chickens; Ciprofloxacin; Drug Residues; Drug Resistance; Half-Life; Injections, Intravenous; Microbial Sensitivity Tests; Molecular Structure | 2011 |
Effects of cytochrome P450 1A substrate (difloxacin) on enzyme gene expression and pharmacokinetics in crucian carp (hybridized Prussian carp).
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Base Sequence; Carps; Ciprofloxacin; Cloning, Molecular; Cytochrome P-450 CYP1A1; DNA, Complementary; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Half-Life; Liver; Molecular Sequence Data; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Tissue Distribution | 2011 |
Short term effects of copper, sulfadiazine and difloxacin on the anaerobic digestion of pig manure at low organic loading rates.
Topics: Anaerobiosis; Animals; Anti-Bacterial Agents; Biofuels; Biotransformation; Ciprofloxacin; Copper Sulfate; Manure; Methanol; Sulfadiazine; Swine | 2012 |
Mutant prevention concentration and phenotypic and molecular basis of fluoroquinolone resistance in clinical isolates and in vitro-selected mutants of Escherichia coli from dogs.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Base Sequence; Ciprofloxacin; Dog Diseases; Dogs; Drug Resistance, Bacterial; Enrofloxacin; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation | 2012 |
Determination of water content by capillary gas chromatography coupled with thermal conductivity detection.
Topics: Amoxicillin; Anti-Bacterial Agents; Chromatography, Gas; Ciprofloxacin; European Union; Indicators and Reagents; Pharmaceutical Preparations; Solvents; Spectinomycin; Theophylline; Thermal Conductivity; Water | 2011 |
Development of a dispersive liquid-liquid microextraction method for the determination of fluoroquinolones in chicken liver by high performance liquid chromatography.
Topics: Animals; Anti-Bacterial Agents; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Limit of Detection; Liquid Phase Microextraction; Liver; Norfloxacin; Regression Analysis; South Africa | 2012 |
Pharmacokinetics of difloxacin in olive flounder Paralichthys olivaceus at two water temperatures.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Flounder; Muscle, Skeletal; Reproducibility of Results; Temperature | 2014 |
Structural and functional response of the soil bacterial community to application of manure from difloxacin-treated pigs.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Bacterial; Integrons; Manure; Rhizosphere; Soil Microbiology; Sus scrofa; Swine; Zea mays | 2014 |
Analysis of quinolone antibiotics in eggs: preparation and characterization of a raw material for method validation and quality control.
Topics: Anti-Bacterial Agents; Chromatography, Liquid; Ciprofloxacin; Eggs; Enrofloxacin; Fluoroquinolones; Food Contamination; Norfloxacin; Oxolinic Acid; Quality Control; Quinolones; Reproducibility of Results | 2012 |
Pharmacokinetics of difloxacin in healthy and E. coli-infected broiler chickens.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Chickens; Ciprofloxacin; Escherichia coli Infections; Female; Injections, Intravenous; Male; Microbial Sensitivity Tests; Poultry Diseases | 2014 |
Determination of fluoroquinolones in chicken feces - a new liquid-liquid extraction method combined with LC-MS/MS.
Topics: Animals; Anti-Bacterial Agents; Chickens; Chromatography, Liquid; Ciprofloxacin; Enrofloxacin; Environmental Monitoring; Feces; Fluoroquinolones; Liquid-Liquid Extraction; Solvents; Tandem Mass Spectrometry | 2014 |
A rapid and reliable assay to determine flumequine, marbofloxacin, difloxacin, and sarafloxacin in commonly consumed meat by micellar liquid chromatography.
Topics: Animals; Anti-Bacterial Agents; Cattle; Chromatography, Liquid; Ciprofloxacin; Drug Residues; Fluoroquinolones; Food Contamination; Goats; Horses; Meat; Poultry; Rabbits; Sheep; Swine | 2019 |
Design of nanostructure chitosan hydrogels for carrying zinc phthalocyanine as a photosensitizer and difloxacin as an antibacterial agent.
Topics: Anti-Bacterial Agents; Chemistry Techniques, Synthetic; Chitosan; Ciprofloxacin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Hydrogels; Indoles; Isoindoles; Molecular Structure; Organometallic Compounds; Photosensitizing Agents; Rheology; Solubility; Spectroscopy, Fourier Transform Infrared; Temperature; Zinc Compounds | 2020 |
Evolution of resistance to fluoroquinolones by dengue virus serotype 4 provides insight into mechanism of action and consequences for viral fitness.
Topics: Adaptation, Biological; Animals; Antiviral Agents; Biological Evolution; Cell Line; Chlorocebus aethiops; Ciprofloxacin; Dengue; Dengue Virus; Drug Resistance, Viral; Enoxacin; Fluoroquinolones; Genetic Fitness; HEK293 Cells; Host Microbial Interactions; Humans; Mutation; Vero Cells; Viral Envelope; Virus Physiological Phenomena | 2021 |