ciprofloxacin and cyclosporine

ciprofloxacin has been researched along with cyclosporine in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (24.24)18.2507
2000's9 (27.27)29.6817
2010's15 (45.45)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Avdeef, A; Tam, KY1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bouillon, A; Cresteil, T; Fontaine, F; Héquet, A; Jolivalt, C; Lesnard, A; Rault, S; Voisin-Chiret, AS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Bause, H; Höver, S; Scholz, J; Schulz, M; Steinfath, M1
Ekberg, H; Forsgren, A; Ostraat, O; Riesbeck, K; Schatz, H; Tufveson, G1
Ekberg, H; Forsgren, A; Riesbeck, K1
Hoey, LL; Lake, KD1
Forsgren, A; Gullberg, M; Riesbeck, K1
Keown, PA; Kim, S; Landsberg, D; Levine, M; Lewis, S; Partovi, N; Primmett, DR; Wrishko, RE1
Pons, G; Rey, E; Tréluyer, JM1
Bernstein, RM1
Inman, RD; Stone, M1
Bell, H; Parslew, R1
Droogh, JM; Fieren, MW; Gyssens, IC; Van Gelder, T; Van Zonneveld, M; Weimar, W1
Borrás-Blasco, J; Conesa-García, V; Gomez-Corrons, A; González-Delgado, M; Marín-Jiménez, F; Navarro-Ruiz, A1
Bressler, B; Sands, BE1
Bermejo, M; Casabó-Alós, VG; Fernández-Teruel, C; Garrigues, TM; González-Alvarez, I; Polli, JE; Ruiz-García, A1
Boehler, A; Rechsteiner, T; Remund, K; Rentsch, K; Russi, EW; Vogt, P1
Balbir-Gurman, A; Bergman, R; Braun-Moscovici, Y; Egozi, D; Markovits, D; Melamed, Y; Ramon, Y; Rozin, AP; Schapira, D; Toledano, K; Ullman, Y1
Milanova, A; Petkova, T; Poźniak, B1

Reviews

7 review(s) available for ciprofloxacin and cyclosporine

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Does ciprofloxacin interact with cyclosporine?
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:1

    Topics: Ciprofloxacin; Clinical Trials as Topic; Cyclosporine; Drug Interactions; Drug Therapy, Combination; Humans; Kidney Diseases

1994
Drug disposition in cystic fibrosis.
    Clinical pharmacokinetics, 1998, Volume: 35, Issue:4

    Topics: Absorption; Anti-Infective Agents; Ciprofloxacin; Cloxacillin; Cyclosporine; Cystic Fibrosis; Fleroxacin; Humans; Theophylline; Tissue Distribution

1998
Drugs and toxins: fact and fancy.
    Current opinion in rheumatology, 1999, Volume: 11, Issue:1

    Topics: Anti-Infective Agents; Ciprofloxacin; Cyclosporine; Drug-Related Side Effects and Adverse Reactions; Humans; Immunosuppressive Agents; Silicones; Toxins, Biological

1999
Recent developments in the therapy of spondyloarthropathies.
    Current rheumatology reports, 2000, Volume: 2, Issue:4

    Topics: Alleles; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Reactive; Chronic Disease; Ciprofloxacin; Cyclosporine; Double-Blind Method; Drug Combinations; Follow-Up Studies; Forecasting; Glucosamine; Humans; Immunosuppressive Agents; Lymecycline; Meta-Analysis as Topic; Methotrexate; Multicenter Studies as Topic; Placebos; Polymorphism, Genetic; Randomized Controlled Trials as Topic; Spondylarthropathies; Sulfasalazine; Time Factors; Tumor Necrosis Factor-alpha

2000
Review article: Medical therapy for fistulizing Crohn's disease.
    Alimentary pharmacology & therapeutics, 2006, Nov-01, Volume: 24, Issue:9

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Ciprofloxacin; Crohn Disease; Cyclosporine; Humans; Immunosuppressive Agents; Infliximab; Intestinal Fistula; Metronidazole

2006

Other Studies

26 other study(ies) available for ciprofloxacin and cyclosporine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Boronic species as promising inhibitors of the Staphylococcus aureus NorA efflux pump: study of 6-substituted pyridine-3-boronic acid derivatives.
    European journal of medicinal chemistry, 2015, May-05, Volume: 95

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Boronic Acids; Ciprofloxacin; Humans; KB Cells; Multidrug Resistance-Associated Proteins; Pyridines; Staphylococcal Infections; Staphylococcus aureus

2015
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Fluconazole is removed by continuous venovenous hemofiltration in a liver transplant patient.
    Journal of molecular medicine (Berlin, Germany), 1995, Volume: 73, Issue:3

    Topics: Anuria; Candidiasis; Ciprofloxacin; Cyclosporine; Fluconazole; Hemofiltration; Humans; Liver Transplantation; Male; Middle Aged; Vancomycin

1995
Enhancement of the immunosuppressive effect of cyclosporin A by ciprofloxacin in a rat cardiac allograft transplantation model.
    Transplant international : official journal of the European Society for Organ Transplantation, 1995, Volume: 8, Issue:2

    Topics: Animals; Cells, Cultured; Ciprofloxacin; Cyclosporine; Drug Synergism; Graft Rejection; Graft Survival; Heart Transplantation; Humans; Interleukin-2; Lymphocytes; Mice; Rats; Rats, Inbred BN; Rats, Wistar; Transplantation, Homologous; Up-Regulation

1995
Ciprofloxacin interferes with the immunosuppressive effects of cyclosporin A on cytokine production in vitro.
    Transplantation proceedings, 1994, Volume: 26, Issue:3

    Topics: Cells, Cultured; Ciprofloxacin; Cyclosporine; Cytokines; Dose-Response Relationship, Drug; Gene Expression; Humans; Immunosuppression Therapy; Interferon-gamma; Interleukin-2; Kinetics; Lymphocytes; RNA, Messenger

1994
Evidence that the antibiotic ciprofloxacin counteracts cyclosporine-dependent suppression of cytokine production.
    Transplantation, 1994, Volume: 57, Issue:2

    Topics: Blotting, Northern; Cells, Cultured; Ciprofloxacin; Cyclosporine; DNA Probes; Drug Combinations; Humans; Interferon-gamma; Interleukin-2; Lectins; Lymphocyte Activation; Lymphocytes; RNA, Messenger

1994
Investigation of a possible interaction between ciprofloxacin and cyclosporine in renal transplant patients.
    Transplantation, 1997, Oct-15, Volume: 64, Issue:7

    Topics: Anti-Infective Agents; Biopsy; Case-Control Studies; Chi-Square Distribution; Ciprofloxacin; Cyclosporine; Drug Interactions; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Reoperation; Retrospective Studies

1997
Pyoderma gangrenosum in childhood--the importance of early recognition.
    European journal of pediatrics, 2002, Volume: 161, Issue:1

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Child, Preschool; Ciprofloxacin; Cyclosporine; Dermatologic Agents; Female; Humans; Prednisolone; Pyoderma Gangrenosum

2002
Yersinia pseudotuberculosis bacteraemia in a kidney transplant patient.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2002, Volume: 17, Issue:12

    Topics: Anti-Infective Agents; Bacteremia; Ciprofloxacin; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Transplantation; Lung Diseases; Male; Middle Aged; Mycophenolic Acid; Prednisolone; Retreatment; Splenic Diseases; Tomography, X-Ray Computed; Yersinia pseudotuberculosis Infections

2002
Ciprofloxacin, but not levofloxacin, affects cyclosporine blood levels in a patient with pure red blood cell aplasia.
    The American journal of the medical sciences, 2005, Volume: 330, Issue:3

    Topics: Adult; Ciprofloxacin; Cyclosporine; Humans; Levofloxacin; Male; Ofloxacin; Red-Cell Aplasia, Pure

2005
In situ kinetic modelling of intestinal efflux in rats: functional characterization of segmental differences and correlation with in vitro results.
    Biopharmaceutics & drug disposition, 2007, Volume: 28, Issue:5

    Topics: Algorithms; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Ciprofloxacin; Colon; Cyclosporine; Dose-Response Relationship, Drug; Fluoroquinolones; Immunosuppressive Agents; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Kinetics; Male; Models, Biological; Molecular Structure; Muscarinic Antagonists; p-Aminohippuric Acid; Permeability; Quinidine; Rats; Rats, Wistar; Vasodilator Agents; Verapamil

2007
Attenuation of airway obliteration by ciprofloxacin in experimental posttransplant bronchiolitis obliterans.
    Transplantation, 2008, Mar-15, Volume: 85, Issue:5

    Topics: Animals; Bronchiolitis Obliterans; Ciprofloxacin; Cyclosporine; Immunosuppressive Agents; Male; Postoperative Complications; Rats; Rats, Inbred BN; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; RNA; Trachea; Transplantation, Heterotopic; Transplantation, Homologous

2008
Large leg ulcers due to autoimmune diseases.
    Medical science monitor : international medical journal of experimental and clinical research, 2011, Volume: 17, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Autoimmune Diseases; Azathioprine; Ciprofloxacin; Cyclophosphamide; Cyclosporine; Female; Humans; Hydroxychloroquine; Hyperbaric Oxygenation; Infliximab; Larva; Leg Ulcer; Male; Methylprednisolone; Middle Aged; Prednisolone; Skin Transplantation; Treatment Outcome; Vancomycin; Vasculitis; Young Adult

2011
The effects of cyclosporine A or activated charcoal co-administration on the pharmacokinetics of enrofloxacin in chickens.
    Poultry science, 2023, Volume: 102, Issue:1

    Topics: Animals; Charcoal; Chickens; Chromatography, Liquid; Ciprofloxacin; Cyclosporine; Enrofloxacin; Fluoroquinolones; Tandem Mass Spectrometry

2023