ciprofloxacin and clinafloxacin

ciprofloxacin has been researched along with clinafloxacin in 77 studies

Research

Studies (77)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (3.90)	18.7374
1990's	43 (55.84)	18.2507
2000's	23 (29.87)	29.6817
2010's	8 (10.39)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cohen, MA; Domagala, JM; Mailloux, GB; Roland, GE; Suto, MJ	1
Bridges, AJ; Culbertson, TP; Domagala, JM; Gambino, L; Hagen, SE; Karrick, G; Porter, K; Sanchez, JP; Sesnie, JA; Spense, FG	1
Domagala, JM; Hagen, SE; Heifetz, CL; Johnson, J	1
Cohen, MA; Domagala, JM; Gogliotti, RD; Gracheck, SJ; Huband, MD; Sanchez, JP; Sesnie, JA; Shapiro, MA	1
García-March, FJ; Jaén-Oltra, J; Pérez-Giménez, F; Salabert-Salvador, MT; Tomás-Vert, F	1
Almstead, JI; Gray, JL; Hu, XE; Kim, NK; Ledoussal, B; Seibel, WL	1
Aubry, A; Cambau, E; Jarlier, V; Matrat, S; Petrella, S; Sougakoff, W	1
Lombardo, F; Obach, RS; Waters, NJ	1
Asahina, Y; Fukuda, Y; Kimura, T; Takei, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Allanki, AD; Chandra Shekhar, A; Narsaiah, B; Shanthan Rao, P; Sijwali, PS	1
Chen, L; Fan, L; He, ZQ; Jiang, L; Lei, HS; Liu, CP; Liu, J; Peng, XM; Xu, XR; Yang, DC; Zhou, CH; Zhou, FW; Zou, YY	1
Geng, RX; Kumar, KV; Zhang, L; Zhou, CH	1
Addla, D; Cai, GX; Geng, RX; Li, S; Ponmani, J; Wang, A; Wang, YN; Xie, D; Zhang, L; Zhang, SL; Zhou, CH	1
Ba, Y; Hou, X; Wang, S; Xu, Z; Yang, H; Zhang, J	1
Blaskovich, MAT; Pham, TDM; Ziora, ZM	1
Blumenthal, RM; Burnham, JC; Guan, L	1
Abo-Askar, H; Qadri, SM; Ueno, Y	1
Burnham, JC; Guan, L	1
Aldridge, KE	1
Citron, DM; Goldstein, EJ	1
Bailey, EM; Kaatz, GW; Lamp, KC; Rybak, MJ; Seo, SM	1
Jabarit-Aldighieri, N; Raoult, D; Torres, H	1
Forstall, GJ; Knapp, CC; Washington, JA	1
Hall, MC; Piddock, LJ; Walters, RN	1
Cassell, GH; Crabb, D; Duffy, LB; Pate, MS; Schmid, T; Waites, KB	1
Barry, AL; Fuchs, PC	1
Allen, SD; Barry, AL; Fuchs, PC; Gerlach, EH; Pfaller, MA	1
Bodey, GP; Ho, DH; LeBlanc, B; Rolston, KV	1
Amyes, SG; Barnes, AC; Hastings, TS; Lewin, CS	1
Andrews, JM; Ashby, JP; Wise, R	1
Jonsson, M; Norrby, SR	1
Boothman, C; King, A; Phillips, I	1
Carlyn, CJ; Doyle, LJ; Knapp, CC; Ludwig, MD; Washington, JA	1
Johnson, DM; Jones, RN	1
Bauernfeind, A	2
Kaatz, GW; Larsson, AJ; Moody, JA; Rotschafer, JC; Walker, KJ; Zabinski, RA	1
Bradley, SF; Harrington, GD; Kauffman, CA; Ramsey, MA; Zarins, LT	1
Cormican, MG; Jones, RN; Marshall, SA	1
Borobio, MV; Conejo, M; Perea, EJ; Ramirez, E; Suarez, AI	1
Appelbaum, PC; Jacobs, MR; Pankuch, GA	1
Eiseman, IA; McGuire, NM; Tack, KJ	1
Dever, JA; Sesnie, JC; Shapiro, MA; VanderRoest, SR	1
Hof, H; Nichterlein, T; Walz, A	1
Fabian, I; Gruss, T; Kletter, Y; Shalit, I; Weiss, K	1
Cohen, MA; Gage, JW; Gracheck, SJ; Huband, MD; Roland, GE; Yoder, SL	1
Cohen, MA; Huband, MD	1
Bornitz, F; Hof, H; Kretschmar, M; Nichterlein, T	1
Desaty, TM; Griffin, TJ; Heifetz, CL; Sesnie, JC; Shapiro, MA	1
Barry, AL; Brown, SD; Fuchs, PC	1
Hoban, DJ; Karlowsky, JA; Zhanel, GG	1
Cohen, MA; Gage, JW; Huband, MD; Roland, GE; Yoder, SL	1
Heisig, P; Jones, ME; Klootwijk, M; Schmitz, FJ; Verhoef, J; Visser, MR	1
Armitage, HT; Kerr, KG; McWhinney, PH	1
Fisher, LM; Pan, XS	1
Asuquo, AE; Jin, YF; Piddock, LJ; Ricci, V	1
Brisse, S; Fluit, AC; Köhrer, K; Martin, N; Milatovic, D; Scheuring, S; Schmitz, FJ; Verhoef, J	1
Hershberger, E; Rybak, MJ	1
Donovan, KD; Gage, JW; Shapiro, MA	1
Coyle, EA; Hershberger, E; Kaatz, GW; Rybak, MJ; Zervos, MJ	1
Edmond, M; Heinemann, B; Seifert, H; Wisplinghoff, H	1
Appelbaum, PC; Davies, TA; Dewasse, BE; Jacobs, MR; Nagai, K; Pankuch, GA	1
Ruef, C	1
Doern, GV; Ernst, EJ; Klepser, ME; Petzold, CR; Rhomberg, P	1
Appelbaum, PC; Davies, T; Edlund, C; El Amin, N; Oh, H	1
Chaves, J; del Carmen Conejo, M; Hernández, G; Joyanes, P; Martínez-Martínez, L; Pascual A, A; Perea, EJ	1
Calvo, A; García, R; Gómez-Lus, ML; Leturia, A; Sevillano, D; Valero, E	1
Kollaras, P; Koumedaki, E; Loumedaki, E; Metallidis, S; Nikolaidis, P; Tsaousoglu, D; Tsona, A	1
Piddock, L; Ricci, V	1
Cabellos, C; Domenech, A; Gudiol, F; Liñares, J; Ribes, S; Tubau, F; Viladrich, PF	1
Guo, HY; Liu, ML; Qi, JJ; Sun, LY	1
Cabeza, JG; Hernandez, J; Llagostera, M; Mensa, J; Montero, T; Ruiz Chaler, M; Sierra, JM; Vila, J	1
Hakanen, AJ; Huovinen, P; Kotilainen, P; Pitkänen, S; Siitonen, A	1
Gross-Tholl, N; Herbold, B; von Keutz, E; Wirnitzer, U	1
Buglak, AA; Dzantiev, BB; Eremin, SA; Lei, HT; Li, X; Shanin, IA; Zherdev, AV	1

Reviews

2 review(s) available for ciprofloxacin and clinafloxacin

Article	Year
Nitroimidazole-containing compounds and their antibacterial and antitubercular activities. European journal of medicinal chemistry, 2019, Oct-01, Volume: 179 Topics: Anti-Bacterial Agents; Bacterial Infections; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Nitroimidazoles	2019
Quinolone antibiotics. MedChemComm, 2019, Oct-01, Volume: 10, Issue:10 Topics:	2019

Trials

1 trial(s) available for ciprofloxacin and clinafloxacin

Article	Year
Initial clinical experience with clinafloxacin in the treatment of serious infections. Drugs, 1995, Volume: 49 Suppl 2 Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Child; Ciprofloxacin; Drug Resistance, Multiple; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Middle Aged; Quinolones	1995

Other Studies

74 other study(ies) available for ciprofloxacin and clinafloxacin

Article	Year
Fluoroquinolones: relationships between structural variations, mammalian cell cytotoxicity, and antimicrobial activity. Journal of medicinal chemistry, 1992, Dec-11, Volume: 35, Issue:25 Topics: Animals; Anti-Infective Agents; Cricetinae; Cricetulus; Fluoroquinolones; Microbial Sensitivity Tests; Structure-Activity Relationship	1992
Synthesis and biological activity of 5-amino- and 5-hydroxyquinolones, and the overwhelming influence of the remote N1-substituent in determining the structure-activity relationship. Journal of medicinal chemistry, 1991, Volume: 34, Issue:3 Topics: Alkylation; Aminoquinolines; Animals; Anti-Bacterial Agents; Bacterial Infections; Chemical Phenomena; Chemistry; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydroxyquinolines; Mice; Microbial Sensitivity Tests; Molecular Structure; Piperazines; Pyrrolidines; Structure-Activity Relationship; Topoisomerase II Inhibitors	1991
Synthesis and biological activity of 5-alkyl-1,7,8-trisubstituted-6-fluoroquinoline-3-carboxylic acids. Journal of medicinal chemistry, 1991, Volume: 34, Issue:3 Topics: 4-Quinolones; Anti-Infective Agents; Chemical Phenomena; Chemistry; Gram-Negative Bacteria; Gram-Positive Bacteria; Methylation; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship	1991
The synthesis, structure-activity, and structure-side effect relationships of a series of 8-alkoxy- and 5-amino-8-alkoxyquinolone antibacterial agents. Journal of medicinal chemistry, 1995, Oct-27, Volume: 38, Issue:22 Topics: Animals; Anti-Bacterial Agents; Bacteria; CHO Cells; Cricetinae; Dermatitis, Phototoxic; Drug Design; Female; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Quinolones; Structure-Activity Relationship	1995
Artificial neural network applied to prediction of fluorquinolone antibacterial activity by topological methods. Journal of medicinal chemistry, 2000, Mar-23, Volume: 43, Issue:6 Topics: Algorithms; Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Neural Networks, Computer; Structure-Activity Relationship	2000
Discovery of (3S)-amino-(4R)-ethylpiperidinyl quinolones as potent antibacterial agents with a broad spectrum of activity and activity against resistant pathogens. Journal of medicinal chemistry, 2003, Aug-14, Volume: 46, Issue:17 Topics: Anti-Bacterial Agents; Bacteria; DNA Gyrase; DNA, Superhelical; Drug Resistance, Bacterial; Escherichia coli; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Piperidines; Quinolones; Stereoisomerism; Structure-Activity Relationship	2003
Expression and purification of an active form of the Mycobacterium leprae DNA gyrase and its inhibition by quinolones. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:5 Topics: Anti-Infective Agents; DNA; DNA Gyrase; DNA, Superhelical; Enzyme Inhibitors; Mycobacterium leprae; Quinolones; Topoisomerase II Inhibitors	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Synthesis and antibacterial activity of novel pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid derivatives carrying the 3-cyclopropylaminomethyl-4-substituted-1-pyrrolidinyl group as a C-10 substituent. Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Animals; Anti-Bacterial Agents; Benzoxazines; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Pyrrolidines; Quinolones; Stereoisomerism; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Emergence of pyrido quinoxalines as new family of antimalarial agents. European journal of medicinal chemistry, 2014, Apr-22, Volume: 77 Topics: Antimalarials; Dose-Response Relationship, Drug; Erythrocytes; Humans; Molecular Structure; Plasmodium falciparum; Pyrazines; Quinoxalines; Structure-Activity Relationship	2014
Design, synthesis, and biological evaluation of dihydroartemisinin-fluoroquinolone conjugates as a novel type of potential antitubercular agents. Bioorganic & medicinal chemistry letters, 2014, Apr-15, Volume: 24, Issue:8 Topics: Antitubercular Agents; Artemisinins; Drug Design; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship	2014
Design and biological evaluation of novel quinolone-based metronidazole derivatives as potent Cu(2+) mediated DNA-targeting antibacterial agents. Bioorganic & medicinal chemistry letters, 2015, Sep-01, Volume: 25, Issue:17 Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Chemistry Techniques, Synthetic; Ciprofloxacin; Copper; DNA, Bacterial; Drug Evaluation, Preclinical; Fibroblasts; Fluoroquinolones; HEK293 Cells; Humans; Metronidazole; Mice; Microbial Sensitivity Tests; Molecular Targeted Therapy; Norfloxacin; Pseudomonas aeruginosa; Quinolones; Structure-Activity Relationship	2015
Discovery of membrane active benzimidazole quinolones-based topoisomerase inhibitors as potential DNA-binding antimicrobial agents. European journal of medicinal chemistry, 2016, Mar-23, Volume: 111 Topics: Anti-Bacterial Agents; Benzimidazoles; Binding Sites; DNA, Bacterial; Dose-Response Relationship, Drug; Drug Discovery; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Quinolones; Structure-Activity Relationship; Topoisomerase Inhibitors	2016
Analysis of macromolecular biosynthesis to define the quinolone-induced postantibiotic effect in Escherichia coli. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:10 Topics: Anti-Infective Agents; Autoradiography; Bacterial Proteins; Cell Division; Cells, Cultured; Ciprofloxacin; DNA, Bacterial; Enoxacin; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones; RNA, Bacterial	1992
Antibacterial activity of the new quinolone CI-960 (PD 127391) against clinical isolates at a major tertiary care center in Saudi Arabia. Chemotherapy, 1992, Volume: 38, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Enterobacter cloacae; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Hospitals, Urban; Klebsiella pneumoniae; Microbial Sensitivity Tests; Norfloxacin; Pseudomonas aeruginosa; Quinolones; Saudi Arabia	1992
Postantibiotic effect of CI-960, enoxacin and ciprofloxacin on Escherichia coli: effect on morphology and haemolysin activity. The Journal of antimicrobial chemotherapy, 1992, Volume: 29, Issue:5 Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Escherichia coli; Fluoroquinolones; Hemolysin Proteins; Microbial Sensitivity Tests; Quinolones; Trimethoprim, Sulfamethoxazole Drug Combination	1992
In vitro antistaphylococcal activities of two investigative fluoroquinolones, CI-960 and WIN 57273, compared with those of ciprofloxacin, mupirocin (pseudomonic acid), and peptide-class antimicrobial agents. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:4 Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mupirocin; Quinolones; Staphylococcus	1992
Comparative activity of ciprofloxacin, ofloxacin, sparfloxacin, temafloxacin, CI-960, CI-990, and WIN 57273 against anaerobic bacteria. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:5 Topics: Anti-Infective Agents; Bacteria, Anaerobic; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones	1992
CI-960, a new fluoroquinolone, for therapy of experimental ciprofloxacin-susceptible and -resistant Staphylococcus aureus endocarditis. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:6 Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Endocarditis, Bacterial; Fluoroquinolones; Kidney; Male; Methicillin Resistance; Microbial Sensitivity Tests; Quinolones; Rabbits; Spleen; Staphylococcal Infections; Staphylococcus aureus; Vancomycin	1992
Susceptibility of Rickettsia conorii, R. rickettsii, and Coxiella burnetii to PD 127,391, PD 131,628, pefloxacin, ofloxacin, and ciprofloxacin. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:11 Topics: Anti-Infective Agents; Ciprofloxacin; Coxiella burnetii; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pefloxacin; Quinolones; Rickettsia; Rickettsia rickettsii; Viral Plaque Assay	1992
Activity of new quinolones against ciprofloxacin-resistant staphylococci. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:8 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Staphylococcus	1991
Phenotypic characterization of quinolone-resistant mutants of Enterobacteriaceae selected from wild type, gyrA type and multiply-resistant (marA) type strains. The Journal of antimicrobial chemotherapy, 1991, Volume: 28, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Enterobacter cloacae; Enterobacteriaceae; Escherichia coli; Fluoroquinolones; Klebsiella pneumoniae; Mutation; Nalidixic Acid; Phenotype; Quinolones; Serratia marcescens; Species Specificity	1991
In vitro susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum to sparfloxacin and PD 127391. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:6 Topics: Anti-Infective Agents; Ciprofloxacin; Clindamycin; Culture Media; Erythromycin; Fluoroquinolones; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma pneumoniae; Tetracycline; Ureaplasma	1991
Antistaphylococcal activity of the fluoroquinolones CI-960, PD 131628, sparfloxacin, ofloxacin and ciprofloxacin. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1991, Volume: 10, Issue:3 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Penicillin Resistance; Staphylococcus; Staphylococcus aureus	1991
Multicenter evaluation of the in vitro activities of three new quinolones, sparfloxacin, CI-960, and PD 131,628, compared with the activity of ciprofloxacin against 5,252 clinical bacterial isolates. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:4 Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines	1991
In vitro activity of PD127,391, a new quinolone against bacterial isolates from cancer patients. Chemotherapy, 1990, Volume: 36, Issue:5 Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Neoplasms	1990
In vitro activities of 4-quinolones against the fish pathogen Aeromonas salmonicida. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:9 Topics: Aeromonas; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enrofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Osmolar Concentration; Oxolinic Acid; Quinolones; Sodium Chloride	1990
In vitro activity of PD 127,391, an enhanced-spectrum quinolone. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:8 Topics: Anti-Infective Agents; Bacteria; Cefuroxime; Chemical Phenomena; Chemistry; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gentamicins; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nalidixic Acid; Ofloxacin	1988
Comparative in vitro activity of PD 127,391, a new fluorinated 4-quinolone derivative. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:8 Topics: Anti-Infective Agents; Bacteria, Aerobic; Ceftazidime; Chemical Phenomena; Chemistry; Ciprofloxacin; Fluoroquinolones; Gentamicins; Gram-Negative Aerobic Bacteria; Humans; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa	1988
The in-vitro activity of PD127,391, a new quinolone. The Journal of antimicrobial chemotherapy, 1988, Volume: 22, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Aerobic Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests	1988
Activities of three investigational fluoroquinolones (BAY y 3118, DU-6859a, and clinafloxacin) against Neisseria gonorrhoeae isolates with diminished susceptibilities to ciprofloxacin and ofloxacin. Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:7 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Quinolones; Spiro Compounds	1995
Modifications for disk diffusion susceptibility testing criteria of clinafloxacin (CI-960, AM-1091, PD127371) and fleroxacin (Ro 23-6240, AM-833) following studies with a challenge panel of ciprofloxacin-resistant clinical isolates. Diagnostic microbiology and infectious disease, 1995, Volume: 21, Issue:4 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones; Sensitivity and Specificity	1995
Comparative in-vitro activities of the new quinolone, Bay y 3118, and ciprofloxacin, sparfloxacin, tosufloxacin, CI-960 and CI-990. The Journal of antimicrobial chemotherapy, 1993, Volume: 31, Issue:4 Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Quinolones	1993
Effect of aerobic and anaerobic environments on antistaphylococcal activities of five fluoroquinolones. Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:2 Topics: Anaerobiosis; Anti-Infective Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Ciprofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Staphylococcus aureus	1995
Susceptibility of ciprofloxacin-resistant staphylococci and enterococci to clinafloxacin. Diagnostic microbiology and infectious disease, 1995, Volume: 21, Issue:1 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enterococcus faecalis; Fluoroquinolones; Methicillin Resistance; Microbial Sensitivity Tests; Quinolones; Staphylococcus aureus	1995
Cross-resistance analysis for DU-6859a, a new fluoroquinolone, compared to six structurally similar compounds (ciprofloxacin, clinafloxacin, fleroxacin, levofloxacin, ofloxacin, and sparfloxacin). Diagnostic microbiology and infectious disease, 1995, Volume: 21, Issue:1 Topics: Anti-Infective Agents; Bacteria, Aerobic; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Fleroxacin; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Spiro Compounds	1995
Comparative activities of eight quinolones against members of the Bacteroides fragilis group. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:6 Topics: Anti-Infective Agents; Bacteroides fragilis; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones	1994
Susceptibilities of 123 Xanthomonas maltophilia strains to clinafloxacin, PD 131628, PD 138312, PD 140248, ciprofloxacin, and ofloxacin. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Xanthomonas	1994
Comparative therapeutic efficacy of clinafloxacin in leucopenic mice. The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:2 Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Female; Fluoroquinolones; Leukopenia; Methicillin Resistance; Mice; Quinolones; Staphylococcal Infections	1997
Excellent activity of newer quinolones on Legionella pneumophila in J774 macrophages. Zentralblatt fur Bakteriologie : international journal of medical microbiology, 1997, Volume: 285, Issue:3 Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacteriological Techniques; Ciprofloxacin; Colony Count, Microbial; Erythromycin; Fluoroquinolones; Gentamicins; Legionella pneumophila; Legionnaires' Disease; Macrophages; Mice; Penicillins; Quinolones; Tumor Cells, Cultured	1997
Enhanced hematopoiesis in sublethally irradiated mice treated with various quinolones. European journal of haematology, 1997, Volume: 58, Issue:2 Topics: Animals; Anti-Infective Agents; Bone Marrow; Cells, Cultured; Ciprofloxacin; Cobalt Radioisotopes; Colony-Forming Units Assay; Culture Media, Conditioned; Fleroxacin; Fluoroquinolones; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cells; Hemoglobins; Interleukin-3; Leukocyte Count; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Norfloxacin; Ofloxacin; Quinolones; Whole-Body Irradiation	1997
In-vitro activity of clinafloxacin, trovafloxacin, and ciprofloxacin. The Journal of antimicrobial chemotherapy, 1997, Volume: 40, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Quinolones	1997
In-vitro susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis and Ureaplasma urealyticum to clinafloxacin, PD 131628, ciprofloxacin and comparator drugs. The Journal of antimicrobial chemotherapy, 1997, Volume: 40, Issue:2 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Clindamycin; Erythromycin; Fluoroquinolones; In Vitro Techniques; Microbial Sensitivity Tests; Mycoplasma hominis; Mycoplasma pneumoniae; Naphthyridines; Quinolones; Tetracycline; Ureaplasma urealyticum	1997
Clinafloxacin (CL 960) is superior to standard therapeutics in the treatment of murine listeriosis and salmonellosis. Zentralblatt fur Bakteriologie : international journal of medical microbiology, 1997, Volume: 286, Issue:3 Topics: Ampicillin; Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Female; Fluoroquinolones; Listeriosis; Mice; Mice, Nude; Microbial Sensitivity Tests; Penicillins; Quinolones; Salmonella enterica; Salmonella Infections, Animal; Salmonella typhimurium	1997
Comparison of the antibacterial activities of the quinolones Bay 12-8039, gatifloxacin (AM 1155), trovafloxacin, clinafloxacin, levofloxacin and ciprofloxacin. The Journal of antimicrobial chemotherapy, 1997, Volume: 40, Issue:5 Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Quinolones; Staphylococcus aureus	1997
Comparative therapeutic efficacy of clinafloxacin in a Pseudomonas aeruginosa mouse renal abscess model. The Journal of antimicrobial chemotherapy, 1998, Volume: 41, Issue:3 Topics: Abscess; Animals; Anti-Infective Agents; Area Under Curve; Ceftazidime; Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Colony Count, Microbial; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Fluoroquinolones; Half-Life; Imipenem; Kidney; Kidney Diseases; Mice; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones; Treatment Outcome	1998
In vitro activities of clinafloxacin against contemporary clinical bacterial isolates from 10 North American centers. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:5 Topics: Anti-Infective Agents; Cefoxitin; Cephamycins; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Quinolones	1998
In vitro activities of six fluoroquinolones against Canadian isolates of vancomycin-sensitive and vancomycin-resistant Enterococcus species. Diagnostic microbiology and infectious disease, 1998, Volume: 31, Issue:2 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Canada; Ciprofloxacin; Drug Resistance, Microbial; Enterococcus; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Vancomycin	1998
Bacterial eradication by clinafloxacin, CI-990, and ciprofloxacin employing MBC test, in-vitro time-kill and in-vivo time-kill studies. The Journal of antimicrobial chemotherapy, 1998, Volume: 41, Issue:6 Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Naphthyridines; Quinolones	1998
Comparative activities of clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, ofloxacin, sparfloxacin, and trovafloxacin and nonquinolones linozelid, quinupristin-dalfopristin, gentamicin, and vancomycin against clinical isolates of ciprofloxacin-re Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:2 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Quinolones; Staphylococcus aureus; Vancomycin; Virginiamycin	1999
Activity of quinolones against viridans group streptococci isolated from blood cultures of patients with haematological malignancy. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1999, Volume: 7, Issue:1 Topics: Adult; Anti-Infective Agents; Bacteremia; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Hematologic Neoplasms; Humans; Naphthyridines; Neutropenia; Risk Factors; Streptococcal Infections; Streptococcus	1999
Streptococcus pneumoniae DNA gyrase and topoisomerase IV: overexpression, purification, and differential inhibition by fluoroquinolones. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:5 Topics: Anti-Infective Agents; Ciprofloxacin; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Escherichia coli; Fluoroquinolones; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Streptococcus pneumoniae	1999
Quinolone accumulation by Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli. The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:1 Topics: Anti-Infective Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Ciprofloxacin; Diffusion; Dose-Response Relationship, Drug; Enoxacin; Enrofloxacin; Escherichia coli; Fluorescence; Fluoroquinolones; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Nalidixic Acid; Pseudomonas aeruginosa; Quinolones; Spheroplasts; Staphylococcus aureus; Temperature	1999
Comparative in vitro activities of ciprofloxacin, clinafloxacin, gatifloxacin, levofloxacin, moxifloxacin, and trovafloxacin against Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, and Enterobacter aerogenes clinical isolates with alterat Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:8 Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Enterobacter cloacae; Fluoroquinolones; Gatifloxacin; Humans; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Molecular Sequence Data; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines	1999
Activities of trovafloxacin, gatifloxacin, clinafloxacin, sparfloxacin, levofloxacin, and ciprofloxacin against penicillin-resistant Streptococcus pneumoniae in an in vitro infection model. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3 Topics: Anti-Infective Agents; Blood Coagulation; Ciprofloxacin; Fibrin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Penicillin Resistance; Pneumococcal Infections; Streptococcus pneumoniae	2000
Comparative therapeutic efficacy of clinafloxacin in a pneumococcal meningitis mouse model. The Journal of antimicrobial chemotherapy, 2000, Volume: 45, Issue:4 Topics: Animals; Anti-Infective Agents; Ceftriaxone; Cephalosporins; Ciprofloxacin; Female; Fluoroquinolones; Meningitis, Pneumococcal; Mice; Microbial Sensitivity Tests; Models, Biological; Streptococcus pneumoniae	2000
Comparison of a rabbit model of bacterial endocarditis and an in vitro infection model with simulated endocardial vegetations. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:7 Topics: Animal Testing Alternatives; Animals; Anti-Infective Agents; Blood Platelets; Cattle; Ciprofloxacin; Disease Models, Animal; Drug Evaluation, Preclinical; Endocarditis, Bacterial; Enterococcus; Fluoroquinolones; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Naphthyridines; Rabbits; Staphylococcus aureus	2000
Comparative activities of ciprofloxacin, clinafloxacin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin, and trovafloxacin against epidemiologically defined Acinetobacter baumannii strains. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:8 Topics: Acinetobacter; Acinetobacter Infections; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Disease Outbreaks; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Germany; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines	2000
In vitro selection of resistance to clinafloxacin, ciprofloxacin, and trovafloxacin in Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:10 Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Naphthyridines; Reverse Transcriptase Polymerase Chain Reaction; Serotyping; Streptococcus pneumoniae	2000
Is antibiotic prophylaxis without risk? Infection, 2000, Volume: 28, Issue:5 Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans	2000
Comparative bactericidal activities of ciprofloxacin, clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, and trovafloxacin against Streptococcus pneumoniae in a dynamic in vitro model. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:3 Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Colony Count, Microbial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Streptococcus pneumoniae; Time Factors	2001
gyrA mutations associated with quinolone resistance in Bacteroides fragilis group strains. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:7 Topics: Amino Acid Substitution; Anti-Infective Agents; Aza Compounds; Bacteroides fragilis; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Quinolines	2001
[The activity of four fluoroquinolones against strains of Pseudomonas aeruginosa with a different sensitivity pattern to ceftazidime and imipenem]. Enfermedades infecciosas y microbiologia clinica, 2001, Volume: 19, Issue:9 Topics: 4-Quinolones; Anti-Infective Agents; Ceftazidime; Ciprofloxacin; Drug Resistance; Fluoroquinolones; Humans; Imipenem; Microbial Sensitivity Tests; Norfloxacin; Pefloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Spain	2001
[Activity of new fluoroquinolones against clinical isolates of Acinetobacter baumannii]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2001, Volume: 14, Issue:4 Topics: Acinetobacter; Acinetobacter Infections; Ampicillin; Anti-Infective Agents; Aza Compounds; Cefepime; Cephalosporins; Ciprofloxacin; Colistin; Fluoroquinolones; Gatifloxacin; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Moxifloxacin; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Opportunistic Infections; Quinolines; Sulbactam; Thienamycins	2001
In-vitro activity of clinafloxacin compared to ciprofloxacin against Acinetobacter baumannii strains isolated from intensive care unit patients. Journal of chemotherapy (Florence, Italy), 2002, Volume: 14, Issue:3 Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Infective Agents; Ciprofloxacin; Critical Care; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests	2002
Accumulation of garenoxacin by Bacteroides fragilis compared with that of five fluoroquinolones. The Journal of antimicrobial chemotherapy, 2003, Volume: 52, Issue:4 Topics: Aza Compounds; Bacteroides fragilis; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Membrane Transport Modulators; Membrane Transport Proteins; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines	2003
Experimental study of clinafloxacin alone and in combination in the treatment of ciprofloxacin-susceptible and -resistant pneumococcal meningitis. Microbial drug resistance (Larchmont, N.Y.), 2003, Volume: 9 Suppl 1 Topics: Animals; Cerebrospinal Fluid; Ciprofloxacin; Disease Models, Animal; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Fluoroquinolones; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Rabbits; Rifampin; Streptococcus pneumoniae; Teicoplanin; Treatment Outcome	2003
[Synthesis and antibacterial activity of 7-(7-aminomethyl-5-azaspiro [2,4] hept-5-yl)-1-cyclopropyl-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid and its analogues]. Yao xue xue bao = Acta pharmaceutica Sinica, 2004, Volume: 39, Issue:3 Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Female; Fluoroquinolones; Gatifloxacin; Male; Mice; Mice, Inbred ICR; Molecular Conformation; Molecular Structure; Quinolines; Spiro Compounds; Staphylococcus aureus; Streptococcus pneumoniae	2004
The selection of resistance to and the mutagenicity of different fluoroquinolones in Staphylococcus aureus and Streptococcus pneumoniae. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2005, Volume: 11, Issue:9 Topics: Aza Compounds; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Levofloxacin; Moxifloxacin; Mutagenicity Tests; Naphthyridines; Ofloxacin; Quinolines; Selection, Genetic; Staphylococcus aureus; Streptococcus pneumoniae	2005
In vitro activities of 11 fluoroquinolones against 816 non-typhoidal strains of Salmonella enterica isolated from Finnish patients with special reference to reduced ciprofloxacin susceptibility. Annals of clinical microbiology and antimicrobials, 2005, Sep-05, Volume: 4 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mutation; Salmonella enterica	2005
Photo-chemically induced DNA effects in the comet assay with epidermal cells of SKH-1 mice after a single oral administration of different fluoroquinolones and 8-methoxypsoralen in combination with exposure to UVA. Mutation research, 2006, Oct-10, Volume: 609, Issue:1 Topics: Administration, Oral; Animals; Cells, Cultured; Ciprofloxacin; Comet Assay; DNA; DNA Damage; Epidermal Cells; Epidermis; Fluoroquinolones; Male; Methoxsalen; Mice; Mice, Hairless; Quinolones; Ultraviolet Rays	2006
Ciprofloxacin and Clinafloxacin Antibodies for an Immunoassay of Quinolones: Quantitative Structure⁻Activity Analysis of Cross-Reactivities. International journal of molecular sciences, 2019, Jan-11, Volume: 20, Issue:2 Topics: Animals; Antibodies; Antibody Specificity; Ciprofloxacin; Fluoroquinolones; Immunization; Immunoassay; Male; Models, Molecular; Quantitative Structure-Activity Relationship; Rabbits	2019