ciprofloxacin has been researched along with ceftazidime in 147 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (1.36) | 18.2507 |
| 2000's | 92 (62.59) | 29.6817 |
| 2010's | 50 (34.01) | 24.3611 |
| 2020's | 3 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Albrecht, HA; Beskid, G; Christenson, JG; Georgopapadakou, NH; Keith, DD; Konzelmann, FM; Pruess, DL; Rossman, PL; Wei, CC | 1 |
| Albrecht, HA; Beskid, G; Christenson, JG; Deitcher, KH; Georgopapadakou, NH; Keith, DD; Konzelmann, FM; Pruess, DL; Wei, CC | 1 |
| Cheng, ML; Duffield, J; Hu, C; Hwang, SB; Ichikawa, Y; Liang, CH; Marby, KA; Rabuka, D; Romero, A; Sears, P; Sgarbi, PW; Shue, YK; Sucheck, SJ; Yao, S | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Choi, TY; Pai, H; Seo, MR | 1 |
| Hatano, K; Ikeda, F; Nakai, T; Takeda, S; Wakai, Y | 1 |
| Chen, YG; Du, XX; Li, LJ; Shen, P; Wei, ZQ; Yu, YS | 1 |
| Alba, L; Chen, Y; Garber, E; Saiman, L; Tabibi, S; Zhou, J | 1 |
| Adams, J; de Oliveira Garcia, D; Doi, Y; Paterson, DL | 1 |
| Barth, AL; Castanheira, M; Gales, AC; Nicoletti, AG; Pereira, AS; Pignatari, AC | 1 |
| Ko, WC; Tsai, SH; Wu, JJ; Yan, JJ | 1 |
| Bradbury, BJ; Buechter, DD; Cheng, J; Deshpande, M; Mushtaq, G; Podos, SD; Pucci, MJ; Thanassi, JA; Thoma, CL; Vigliotti, GA | 1 |
| Dumas, JL; Köhler, T; Reinhardt, A; Ricou, B; Rohner, P; van Delden, C; Wood, P | 1 |
| Caniça, M; Ferreira, E; Leitão, J; Manageiro, V; Mendonça, N | 1 |
| Cauda, R; Citton, R; D'Inzeo, T; Fadda, G; Fiori, B; Montuori, E; Posteraro, B; Sanguinetti, M; Spanu, T; Trecarichi, EM; Tumbarello, M | 1 |
| Bonomo, RA; Endimiani, A; Hujer, AM; Hujer, KM; Luzzaro, F; Mantengoli, E; Migliavacca, R; Pagani, L; Rossolini, GM; Toniolo, A | 1 |
| Ariza, J; Dominguez, MA; Gudiol, F; Guzmán, A; Peña, C; Pujol, M; Suarez, C; Tubau, F | 1 |
| Adams, J; Paterson, DL; Peleg, AY | 1 |
| Kamat, V; Sekar, U; Toleman, MA; Vinodh, H; Walsh, TR | 1 |
| Kwon, DH; Lu, CD | 1 |
| Avlami, A; Daikos, GL; Katsilambros, N; Kosmidis, C; Petrikkos, G; Psychogiou, M; Stefanou, I; Tassios, PT; Vasilakopoulou, A | 1 |
| Bille, J; Lartigue, MF; Nordmann, P; Poirel, L; Wenger, A; Zinsius, C | 1 |
| Borrell, N; Maciá, MD; Moya, B; Oliver, A; Pérez, JL; Plasencia, V | 1 |
| Castanheira, M; Jones, RN; Mendes, RE; Sader, HS; Toleman, MA; Walsh, TR | 1 |
| Afkou, Z; Ikonomidis, A; Labrou, M; Maniatis, AN; Pournaras, S; Sofianou, D; Tsakris, A | 1 |
| Chen, YT; Lauderdale, TL; Liao, TL; Shiau, YR; Shu, HY; Su, IJ; Tsai, SF; Wu, KM; Yan, JJ | 1 |
| Carmeli, Y; Chmelnitsky, I; Leavitt, A; Navon-Venezia, S; Schwaber, MJ | 1 |
| Hovde, LB; Kroeger, LA; Mitropoulos, IF; Rotschafer, JC; Schafer, J | 1 |
| Beceiro, A; Bou, G; Canle, D; Fernández, A; Lasa, I; Latasa, C; Mallo, S; Molina, F; Pérez, A; Pérez, S; Poza, M; Tomás, Mdel M; Villanueva, R | 1 |
| Bajolet, O; Berthelot, P; Bingen, E; Couetdic, G; Favre, R; Grattard, F; Hocquet, D; Husson, MO; Jeannot, K; Mariani-Kurkdjian, P; Marty, N; Plésiat, P; Roussel-Delvallez, M | 1 |
| Fung, CP; Hsieh, YP; Hu, WS; Lin, JF; Liu, CP; Yao, SM | 1 |
| Liu, Y; Shi, W; Wang, M; Wu, S; Xu, X; Ye, X; Zhang, Y | 1 |
| Chen, M; Guo, P; Sun, H; Wang, H; Xu, Y; Yang, Q; Zhu, Y | 1 |
| Bouza, E; Cercenado, E; Coll, P; Gutiérrez, O; Juan, C; Navarro, F; Oliver, A; Pérez, JL | 1 |
| Iredell, JR; Partridge, SR; Zong, Z | 1 |
| Chen, T; Khalil, H; Riffon, R; Wang, R; Wang, Z | 1 |
| Arakawa, Y; Suzuki, S; Wachino, J; Yamane, K | 1 |
| Bonnet, R; Caniça, M; Ferreira, E; Manageiro, V; Mendonça, N; Robin, F; Salgado, MJ | 1 |
| Cai, JC; Chen, GX; Zhang, R; Zhou, HW | 1 |
| Adams-Haduch, JM; de Oliveira Garcia, D; Doi, Y; Freire, MP; Leite, D; Padoveze, MC; Paterson, DL; Silveira, FP; Szabo, D; Vaz, TM | 1 |
| Castanheira, M; Deshpande, LM; Martin, CA; Morita, K; Ribes, JA; Sader, HS | 1 |
| Bethel, CR; Bonomo, RA; Carias, LL; Endimiani, A; Fox, WR; Hall, GS; Hujer, AM; Hujer, KM; Hutton, RA; Jacobs, MR; Jenkins, SG; Paterson, DL; Perez, F; Rice, LB; Tenover, FC | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Bertolini, T; Chow, C; Froelich, JM; Hermann, T; Murphy, DE; Sun, Z; Wall, D; Webber, SE; Zhou, Y | 1 |
| Carrillo, B; Esparza-Ahumada, S; Garza-Ramos, U; Hernández, E; Jones, RN; Morfin-Otero, R; Rodriguez-Noriega, E; Sader, HS; Sanchez, A; Silva-Sanchez, J | 1 |
| Apisarnthanarak, A; Kiratisin, P; Laesripa, C; Saifon, P | 1 |
| Alba, V; Blasco, MD; Espinal, P; Fernández-Cuenca, F; Marti, S; Pascual, A; Ruiz, M; Sánchez-Céspedes, J; Vila, J | 1 |
| Badur, S; Cagatay, AA; Carrër, A; Eraksoy, H; Nordmann, P; Poirel, L | 1 |
| Carmeli, Y; Chmelnitsky, I; Navon-Venezia, S; Strahilevitz, J | 1 |
| Amsler, KM; Bush, K; Davies, TA; Jacobs, MR; Shang, W | 1 |
| Albertí, S; Beceiro, A; Bou, G; Garau, M; Gutiérrez, O; Juan, C; Oliver, A; Pérez, JL | 1 |
| Cattoir, V; Nordmann, P; Poirel, L | 1 |
| Fujimoto, S; Ike, Y; Okuzumi, K; Tanimoto, K; Tomita, H | 1 |
| Wang, H; Wu, X; Zhao, X | 1 |
| Afif, C; Bagattini, M; Daoud, Z; Di Popolo, A; Khan, AU; Triassi, M; Vitale, D; Zarrilli, R | 1 |
| Adams-Haduch, JM; Doi, Y; Harrison, LH; Muto, CA; Pasculle, AW; Paterson, DL; Potoski, BA; Sidjabat, HE | 1 |
| Chen, H; Chen, M; Wang, H; Yang, H; Yang, Q | 1 |
| Amicosante, G; De Luca, F; Luzzaro, F; Migliavacca, R; Mugnaioli, C; Pagani, L; Perilli, M; Pini, B; Pollini, S; Rossolini, GM; Spalla, M; Toniolo, A | 1 |
| Berçot, B; Nordmann, P; Poirel, L | 1 |
| Bennett, JW; Herrera, ML; Jorgensen, JH; Lewis, JS; Wickes, BW | 1 |
| Chang, FY; Chen, JH; Fung, CP; Lai, YK; Lin, CJ; Lin, JC; Ma, L; Siu, LK | 1 |
| Chen, Z; Deng, Y; Huang, L; Liu, J; Lü, D; Ma, J; Wang, M; Wang, X; Xu, X; Zeng, Z; Zhang, Y | 1 |
| Andlovic, A; Jeverica, S; Karisik, E; Koren, S; Krizan-Hergouth, V; Livermore, DM; Mesko Meglic, K; Müller-Premru, M; Palepou, MF; Pike, R; Seme, K; Woodford, N | 1 |
| Baptista, BC; Correia, JD; da Fonseca, JD; Martínez-Martínez, L; Pomba, C | 1 |
| Bell, JM; Castanheira, M; Deshpande, LM; Jones, RN; Mendes, RE; Turnidge, JD | 1 |
| Asensi, MD; Gales, AC; Monteiro, J; Peirano, G; Santos, AF | 1 |
| Bell, JM; Castanheira, M; Jones, RN; Mathai, D; Turnidge, JD | 1 |
| Juan, C; Maciá, MD; Mena, A; Mulet, X; Oliver, A; Pérez, JL | 1 |
| Baraniak, A; Bedenic, B; Fiett, J; Gniadkowski, M; Jajic-Bencic, I; Literacka, E; Tonkic, M | 1 |
| Duljasz, W; Gniadkowski, M; Jebelean, C; Sitter, S; Wojna, A | 1 |
| Guo, Q; Hooper, DC; Wang, M; Wang, X; Wu, S; Xu, X; Ye, X | 1 |
| Della-Latta, P; Dib-Hajj, F; Dougherty, BA; Gootz, TD; He, W; Huard, RC; Lescoe, MK | 1 |
| Attrée, I; Ducruix, A; El Garch, F; Llanes, C; Muller, C; Phan, G; Plésiat, P; Vettoretti, L | 1 |
| Asgarali, A; Mark, BL; Oliver, A; Stubbs, KA; Vocadlo, DJ | 1 |
| Delauné, A; Espié, E; Fabre, L; Galimand, M; Guesnier, F; Lassen, J; Nygard, K; Pardos de la Gandara, M; Polomack, L; Weill, FX | 1 |
| Choi, SH; Jeong, JY; Jun, JB; Kim, ES; Kim, MN; Kim, YS; Lee, SO; Woo, JH | 1 |
| Christiansen, LE; Ciofu, O; Høiby, N; Kirkby, N; Mandsberg, LF; Poulsen, HE | 1 |
| Bartolomé, R; Coelho, A; González-López, JJ; Larrosa, MN; Lavilla, S; Prats, G | 1 |
| Baum, EZ; Bush, K; Crespo-Carbone, SM; Davies, TA; Foleno, BD; He, W; Morrow, BJ; Queenan, AM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Capone, A; D'Andrea, MM; D'Arezzo, S; Giani, T; Luzzaro, F; Petrosillo, N; Rossolini, GM; Visca, P | 1 |
| Badal, RE; Bouchillon, SK; Hawser, SP; Hoban, DJ; Hsueh, PR; Paterson, DL | 1 |
| Brunner, LS; Haas, W; Lee, JC; Morris, TW; Pillar, CM; Zurenko, GE | 1 |
| Baraniak, A; Fiett, J; Filczak, K; Gniadkowski, M; Herda, M; Hryniewicz, W; Izdebski, R; Kern-Zdanowicz, I; Łopaciuk, U | 1 |
| Du, X; Ji, S; Jiang, Y; Li, L; Shen, P; Wei, Z; Yu, Y | 1 |
| Hancock, RE; Kiffer, CR; Mendes, CM; Sampaio, JL; Schurek, KN; Sinto, S | 1 |
| Carattoli, A; Ellington, MJ; Karisik, E; Livermore, DM; Underwood, A; Woodford, N | 1 |
| Acosta, J; Chaves, F; Juan, C; Oliver, A; Otero, JR; Sanz, F; Viedma, E; Zamorano, L | 1 |
| Chung, DR; Ko, KS; Peck, KR; Son, JS; Song, JH; Suh, JY | 1 |
| Cho, HS; Giske, CG; Lee, K; Sundman, K; Toleman, MA; Walsh, TR; Yong, D | 1 |
| Albertí, S; Juan, C; Mulet, X; Oliver, A; Pérez, JL; Zamorano, L | 1 |
| Gebreyes, WA; Rajamohan, G; Srinivasan, VB | 1 |
| Bulik, CC; Crandon, JL; Nicolau, DP | 1 |
| Aggen, JB; Armstrong, ES; Bonomo, RA; Choudhary, Y; Endimiani, A; Hujer, AM; Hujer, KM | 1 |
| Ichiishi, S; Mikamo, H; Nakao, K; Shibata, T; Tanaka, K; Watanabe, K | 1 |
| Chen, H; Chen, M; Sun, H; Wang, H; Xu, Y; Yang, Q | 1 |
| Girlich, D; Nordmann, P; Poirel, L | 1 |
| Courvalin, P; Coyne, S; Guigon, G; Périchon, B | 1 |
| Bonnet, R; Casin, I; Doublet, B; Fabre, L; Le Fleche, A; Robin, F; Weill, FX | 1 |
| Giske, CG; Hermansen, NO; Leegaard, TM; Lia, A; Rajendra, Y; Ranheim, TE; Rydberg, J; Samuelsen, O; Sundsfjord, A; Toleman, MA; Walder, M; Walsh, TR | 1 |
| Bulik, CC; Christensen, H; Nicolau, DP | 1 |
| Ge, Y; Juan, C; Oliver, A; Pérez, JL; Zamorano, L | 1 |
| Avdeef, A; Sun, N; Tam, KY; Tsinman, O | 1 |
| Dunman, PM; Hood, MI; Jacobs, AC; Sayood, K; Skaar, EP | 1 |
| Aquino, EE; León, CF; Otero, DM; Robledo, IE; Santana, JL; Santé, MI; Vázquez, GJ | 1 |
| Chen, HC; King, CH; Lai, JF; Lauderdale, TL; Shiau, YR | 1 |
| Ge, Y; Juan, C; Moya, B; Oliver, A; Pérez, JL; Zamorano, L | 1 |
| Beceiro, A; Bou, G; Doumith, M; Livermore, DM; Tomás, M; Turton, JF; Warner, M; Woodford, N | 1 |
| Chang, SC; Chen, YC; Hsia, KC; Li, SY; Liao, MH; Lin, YC; Sheng, WH | 1 |
| Choi, JY; Ko, KS; Lee, MY; Park, YK; Peck, KR; Rhee, JY; Shin, JY; Song, JH | 1 |
| Carmeli, Y; Chmelnitsky, I; Goren, MG; Navon-Venezia, S | 1 |
| Dantier, C; Desarbre, E; Page, MG | 1 |
| Carmeli, Y; Chmelnitsky, I; Goren, MG; Leavitt, A; Navon-Venezia, S; Ofek, I | 1 |
| Chang, FY; Chen, TL; Fung, CP; Huang, LY; Lu, PL; Siu, LK | 1 |
| Barber, M; Eberly, LE; Feeney, LA; Miller, GH; Summers, A; Wortmann, G; Zapor, MJ | 1 |
| Badal, RE; Baquero, F; Bouchillon, SK; Cantón, R; Hawser, SP; Hoban, DJ | 1 |
| Badal, RE; Bouchillon, SK; DiPersio, J; Hawser, SP; Hoban, DJ; Labombardi, VJ | 1 |
| Abele-Horn, M; Claus, H; Elias, J; Engelhardt, K; Frosch, M; Joseph, B; Oesterlein, A; Schoen, C; Turnwald, D; Valenza, G | 1 |
| Mima, T; Schweizer, HP | 1 |
| Jiang, Y; Shen, P; Wei, Z; Yu, D; Yu, Y; Zhou, Z | 1 |
| Bertrand, X; Dehecq, B; Hocquet, D; Mariotte, P; Plésiat, P; Talon, D | 1 |
| Harada, S; Ishii, Y; Saga, T; Tateda, K; Yamaguchi, K | 1 |
| Bai, N; Cai, Y; Li, R; Liang, B; Liu, Y; Wang, R | 1 |
| Bialek, S; Chevalier, J; Davin, A; Lavigne, JP; Leflon-Guibout, V; Marcon, E; Moreau, R; Nicolas-Chanoine, MH; Pagès, JM | 1 |
| Clark, M; Doolittle, J; Giddings, MC; Khatun, J; Ramkissoon, K; Secrest, A; Su, HC; Wolfgang, MC | 1 |
| Blázquez, J; Couce, A; Rodríguez-Rojas, A | 1 |
| Chang, FY; Chen, TL; Fung, CP; Hsueh, PR; Ko, WC; Kuo, SC; Lee, YT; Siu, LK | 1 |
| Bogaerts, P; Buvens, G; Glupczynski, Y; Lauwers, S; Piérard, D | 1 |
| Bae, IK; Jeong, SH; Kim, J; Lee, K; Suh, B; Yong, D | 1 |
| Hamprecht, A; Higgins, PG; Schneiders, T; Seifert, H | 1 |
| Abramite, JA; Arcari, JT; Barham, RA; Brown, MF; Che, Y; Chen, JM; Chung, SW; Collantes, EM; Desbonnet, C; Doroski, M; Doty, J; Engtrakul, JJ; Harris, TM; Huband, M; Knafels, JD; Leach, KL; Liu, S; Marfat, A; Marra, A; McElroy, E; Melnick, M; Menard, CA; Montgomery, JI; Mullins, L; Noe, MC; O'Donnell, J; Oliver, R; Penzien, J; Plummer, MS; Price, LM; Reilly, U; Shanmugasundaram, V; Thoma, C; Uccello, DP; Warmus, JS; Wishka, DG | 1 |
| Anderson, KC; Kellogg, GE; Sarkar, A | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Maravić, A; Odžak, R; Skočibušić, M | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Fernando, DM; Gorityala, BK; Goswami, S; Guchhait, G; Kumar, A; Schweizer, F; Zhanel, GG | 1 |
| Drenjančević, D; Harej, A; Kraljević, TG; Pavelić, SK; Raić-Malić, S; Sedić, M; Stepanić, V; Talapko, J | 1 |
| Allam, A; Alves de Sousa, R; Artaud, I; Dumont, E; Maigre, L; Pagès, JM; Vergalli, J | 1 |
| Dong, N; Dou, X; Shan, A; Wang, J; Zhu, X | 1 |
| Domalaon, R; Gorityala, BK; Goswami, S; Idowu, T; Lyu, Y; Schweizer, F; Shan, A; Yang, X; Zhanel, GG | 1 |
| Bojkovic, J; Dean, CR; Dobler, M; Dzink-Fox, J; Glick, M; Hamann, LG; Kerrigan, J; Lanieri, L; Lenoir, F; Lilly, MD; Liu, E; Lu, Y; McKenney, D; Nunez, J; Osborne, C; Parker, DT; Patnaik, A; Peng, Y; Piizzi, G; Ranjitkar, S; Sprague, ER; Tommasi, R; Wang, B; Wang, H; Wattanasin, S; Xie, L; Yang, X; Yu, D | 1 |
| Björkling, F; Bonke, G; Franzyk, H; Hansen, AM; Hogendorf, WFJ; Kongstad, KT; Nielsen, J; Nielsen, PE; Tomczak, M; Urbas, M; Zabicka, D | 1 |
| Chen, T; Li, Z; Lyu, Y; Shan, A; Shang, L; Yang, Y; Zhu, J | 1 |
| Ammeter, D; Idowu, T; Rossong, H; Schweizer, F; Zhanel, GG | 1 |
| Jiang, K; Lin, F; Wu, H; Xiao, J; Xiao, Z; Yan, X; Yu, J; Yue, Y; Zhao, M; Zhou, X | 1 |
| Brunst, S; Burgers, LD; Frank, D; Fürst, R; Gobec, S; Martinelli, G; Proschak, A; Proschak, E; Rotter, MJ; Sosič, I; Weizel, L; Wichelhaus, TA | 1 |
| Benada, O; Bogdanová, K; Dávidová, E; Do Pham, DD; Fišer, R; Galandáková, A; Helusová, M; Kolář, M; Krásný, L; Křížek, T; Mikušová, G; Mojr, V; Pohl, R; Pospíšil, J; Rejman, D; Šanderová, H; Sedláková, MH; Sudzinová, P; Večeřová, R; Vítovská, D | 1 |
1 review(s) available for ciprofloxacin and ceftazidime
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for ciprofloxacin and ceftazidime
| Article | Year |
|---|---|
In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections.
Topics: Anti-Bacterial Agents; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Skin Diseases, Bacterial; Staphylococcus | 2008 |
145 other study(ies) available for ciprofloxacin and ceftazidime
| Article | Year |
|---|---|
Dual-action cephalosporins: cephalosporin 3'-quinolone carbamates.
Topics: Animals; Anti-Bacterial Agents; Carbamates; Cefotaxime; Cephalosporins; Chromatography, High Pressure Liquid; Ciprofloxacin; Escherichia coli; Mice; Pseudomonas aeruginosa; Spectrophotometry, Infrared; Staphylococcus aureus; Streptococcus pneumoniae | 1991 |
Dual-action cephalosporins incorporating a 3'-tertiary-amine-linked quinolone.
Topics: beta-Lactamases; Cephalosporins; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Resistance, Microbial; Drug Stability; Gram-Negative Bacteria; Gram-Positive Bacteria; Molecular Structure; Nitrogen; Quinolines; Structure-Activity Relationship | 1994 |
Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Drug Evaluation, Preclinical; Female; Humans; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Structure-Activity Relationship | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Association of QnrB determinants and production of extended-spectrum beta-lactamases or plasmid-mediated AmpC beta-lactamases in clinical isolates of Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cephalosporins; Drug Resistance, Multiple, Bacterial; Escherichia coli; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Plasmids; Quinolones | 2007 |
In vitro and in vivo activities of a new cephalosporin, FR264205, against Pseudomonas aeruginosa.
Topics: Animals; beta-Lactamases; Burns; Cephalosporins; Drug Resistance, Multiple, Bacterial; Lung Diseases; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Urinary Tract Infections; Wound Infection | 2007 |
Plasmid-mediated KPC-2 in a Klebsiella pneumoniae isolate from China.
Topics: beta-Lactam Resistance; beta-Lactamases; Carbapenems; China; Hospitals, University; Humans; Klebsiella pneumoniae; Molecular Sequence Data; Plasmids | 2007 |
Antimicrobial susceptibility and synergy studies of Burkholderia cepacia complex isolated from patients with cystic fibrosis.
Topics: Anti-Bacterial Agents; Burkholderia cepacia complex; Burkholderia Infections; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests | 2007 |
Coproduction of novel 16S rRNA methylase RmtD and metallo-beta-lactamase SPM-1 in a panresistant Pseudomonas aeruginosa isolate from Brazil.
Topics: Amino Acid Sequence; Aminoglycosides; beta-Lactamases; Brazil; Carbapenems; Cloning, Molecular; Drug Resistance, Multiple, Bacterial; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections | 2007 |
First report of plasmid-mediated qnrA1 in a ciprofloxacin-resistant Escherichia coli strain in Latin America.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Conjugation, Genetic; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Integrons; Latin America; Molecular Sequence Data; Plasmids | 2007 |
Prevalence of plasmid-mediated quinolone resistance determinants QnrA, QnrB, and QnrS among clinical isolates of Enterobacter cloacae in a Taiwanese hospital.
Topics: Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Genes, Bacterial; Hospitals; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Prevalence; Quinolones; Taiwan | 2007 |
In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens.
Topics: Animals; Anti-Infective Agents; Drug Resistance, Bacterial; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Mice; Microbial Sensitivity Tests; Quinolones; Thiazoles | 2007 |
Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Drug Resistance, Bacterial; Humans; Longitudinal Studies; Pneumonia, Ventilator-Associated; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections | 2007 |
Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal.
Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Middle Aged; Portugal | 2007 |
Predictors of mortality in patients with bloodstream infections caused by extended-spectrum-beta-lactamase-producing Enterobacteriaceae: importance of inadequate initial antimicrobial treatment.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Cross Infection; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli; Female; Humans; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Middle Aged; Predictive Value of Tests; Proteus mirabilis; Risk Factors; Survival Analysis; Treatment Outcome | 2007 |
Spread in an Italian hospital of a clonal Acinetobacter baumannii strain producing the TEM-92 extended-spectrum beta-lactamase.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Cross Infection; Humans; Italy; Microbial Sensitivity Tests | 2007 |
Effects of carbapenem exposure on the risk for digestive tract carriage of intensive care unit-endemic carbapenem-resistant Pseudomonas aeruginosa strains in critically ill patients.
Topics: Adult; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Carrier State; Critical Illness; Endemic Diseases; Female; Gastrointestinal Tract; Humans; Imipenem; Incidence; Intensive Care Units; Male; Middle Aged; Pharynx; Pseudomonas aeruginosa; Pseudomonas Infections; Rectum; Risk Factors | 2007 |
Tigecycline Efflux as a Mechanism for Nonsusceptibility in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Ethidium; Gene Expression Regulation, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Minocycline; Molecular Sequence Data; Sequence Analysis, DNA; Tigecycline | 2007 |
blaVIM-2-harboring integrons isolated in India, Russia, and the United States arise from an ancestral class 1 integron predating the formation of the 3' conserved sequence.
Topics: Base Sequence; beta-Lactamases; DNA Transposable Elements; Evolution, Molecular; Genes, Bacterial; Humans; India; Integrons; Molecular Sequence Data; Pseudomonas aeruginosa; Russia; United States | 2007 |
Polyamine effects on antibiotic susceptibility in bacteria.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Drug Resistance, Bacterial; Drug Synergism; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Polyamines; Spermine; Staphylococcus aureus | 2007 |
Enterobacteriaceae bloodstream infections: presence of integrons, risk factors, and outcome.
Topics: Bacteremia; Community-Acquired Infections; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterobacteriaceae Infections; Gene Transfer, Horizontal; Humans; Infectious Disease Transmission, Professional-to-Patient; Integrons; Microbial Sensitivity Tests; Nucleic Acid Amplification Techniques; Polymerase Chain Reaction; Prospective Studies; Risk Factors; Sequence Analysis, DNA; Treatment Outcome | 2007 |
Extended-spectrum beta-lactamases of the CTX-M type now in Switzerland.
Topics: Anti-Bacterial Agents; beta-Lactamases; Community-Acquired Infections; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli; Hospitals, University; Humans; Microbial Sensitivity Tests; Molecular Epidemiology; Polymerase Chain Reaction; Prevalence; Switzerland | 2007 |
Influence of high mutation rates on the mechanisms and dynamics of in vitro and in vivo resistance development to single or combined antipseudomonal agents.
Topics: Animals; Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Disease Models, Animal; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Lung; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 2007 |
Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital.
Topics: Acinetobacter; Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Brazil; Codon, Terminator; Cross Infection; Drug Resistance, Multiple, Bacterial; Gene Transfer, Horizontal; Genes, Bacterial; Hospitals; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Open Reading Frames; Plasmids; Pseudomonas putida; Transcription, Genetic | 2007 |
First occurrence of an Escherichia coli clinical isolate producing the VIM-1/VIM-2 hybrid metallo-beta-lactamase VIM-12.
Topics: Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamases; Conjugation, Genetic; Escherichia coli; Escherichia coli Infections; Humans; Male; Microbial Sensitivity Tests; Plasmids; Recombination, Genetic | 2007 |
Sequencing and comparative genomic analysis of pK29, a 269-kilobase conjugative plasmid encoding CMY-8 and CTX-M-3 beta-lactamases in Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Conjugation, Genetic; Genomics; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA | 2007 |
Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Hospitals; Humans; Israel; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Epidemiology | 2007 |
Colistin methanesulfonate against multidrug-resistant Acinetobacter baumannii in an in vitro pharmacodynamic model.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Ceftazidime; Colistin; Colony Count, Microbial; Drug Combinations; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests | 2007 |
Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate.
Topics: Bacterial Proteins; Base Sequence; beta-Lactamases; Carrier Proteins; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Genes, MDR; Genetic Vectors; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Porins | 2007 |
Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteremia; beta-Lactams; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Fluoroquinolones; Genotype; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Bacterial Proteins; Base Sequence; beta-Lactamases; Drug Resistance, Bacterial; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Bacterial; Humans; Imipenem; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Nucleic Acid | 2007 |
Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1.
Topics: Anti-Infective Agents; Base Sequence; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae; Gene Expression Regulation, Bacterial; Genes, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid | 2007 |
Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals.
Topics: Acinetobacter; Acinetobacter Infections; Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Blotting, Southern; Carbapenems; China; Chloramphenicol; Colistin; Cross Infection; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Hospitals; Humans; Imipenem; Integrons; Microbial Sensitivity Tests; Molecular Epidemiology; Molecular Sequence Data; Rifampin; Sequence Analysis, DNA | 2007 |
Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Chromosomes, Bacterial; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Integrons; Molecular Epidemiology; Molecular Sequence Data; Mutation; Plasmids; Polymerase Chain Reaction; Porins; Pseudomonas aeruginosa; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Spain | 2007 |
RmtC 16S rRNA methyltransferase in Australia.
Topics: Aminoglycosides; Anti-Bacterial Agents; Australia; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Drug Resistance, Bacterial; Genes, rRNA; Humans; Methyltransferases; Microbial Sensitivity Tests; Proteus Infections; Proteus mirabilis; RNA, Ribosomal, 16S | 2008 |
Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa.
Topics: Aminoglycosides; Anti-Bacterial Agents; Carbenicillin; Ceftazidime; Ciprofloxacin; Drug Resistance, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Novobiocin; Ofloxacin; Piperacillin; Polyethyleneimine; Pseudomonas aeruginosa; Pseudomonas Infections; Rifampin; Ticarcillin; Tobramycin | 2008 |
Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan.
Topics: Anti-Bacterial Agents; Conjugation, Genetic; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Fluoroquinolones; Hospitals; Humans; Japan; Microbial Sensitivity Tests; Plasmids; Prevalence | 2008 |
The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition.
Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Arginine; Aztreonam; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acid; Computer Simulation; Imipenem; Isoelectric Focusing; Kinetics; Klebsiella pneumoniae; Lysine; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Penicillins; Protein Conformation; Protein Structure, Tertiary | 2008 |
Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Carbapenems; China; Conjugation, Genetic; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Hospitals, University; Humans; Hydrolysis; Intensive Care Units; Klebsiella pneumoniae; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Serratia marcescens | 2008 |
Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Brazil; Cephalosporins; Disease Outbreaks; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Polymerase Chain Reaction | 2008 |
IMP-15-producing Pseudomonas aeruginosa strain isolated in a U.S. medical center: a recent arrival from Mexico.
Topics: Adult; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Hospitals; Humans; Imipenem; Kentucky; Male; Mexico; Pseudomonas aeruginosa; United States | 2008 |
Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States.
Topics: Aged; Bacterial Proteins; Base Sequence; beta-Lactamases; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Molecular Epidemiology; Plasmids; Quinolones; United States | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Antibacterial activity in serum of the 3,5-diamino-piperidine translation inhibitors.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Combinatorial Chemistry Techniques; Diamines; Escherichia coli; Mice; Microbial Sensitivity Tests; Molecular Structure; Piperidines; Protein Biosynthesis; Pseudomonas aeruginosa; Structure-Activity Relationship | 2008 |
Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico.
Topics: Bacterial Proteins; beta-Lactamases; Cross Infection; Electrophoresis, Gel, Pulsed-Field; Humans; Integrons; Mexico; Models, Genetic; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections | 2008 |
Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic.
Topics: Adult; Bacterial Proteins; beta-Lactamases; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Endemic Diseases; Escherichia coli; Escherichia coli Infections; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Polymerase Chain Reaction; Sequence Analysis, DNA; Thailand | 2008 |
Characterization of the carbapenem-hydrolyzing oxacillinase oxa-58 in an Acinetobacter genospecies 3 clinical isolate.
Topics: Acinetobacter; Acinetobacter Infections; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; Humans; Imipenem; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA | 2008 |
Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey.
Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Turkey | 2008 |
Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates.
Topics: Anti-Infective Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Ciprofloxacin; Drug Resistance, Bacterial; Enterobacter cloacae; Genes, Bacterial; Microbial Sensitivity Tests; Plasmids; Quinolones | 2008 |
Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Genes, Bacterial; Genetic Variation; Humans; Imipenem; Integrons; Kinetics; Meropenem; Molecular Sequence Data; Phylogeny; Pseudomonas aeruginosa; Pseudomonas Infections; Recombinant Proteins; Sequence Homology, Amino Acid; Spain; Thienamycins | 2008 |
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.
Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids | 2008 |
Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation.
Topics: Base Sequence; beta-Lactam Resistance; Carbapenems; DNA Primers; DNA, Bacterial; Doripenem; Fluoroquinolones; Genes, Bacterial; Humans; In Vitro Techniques; Meropenem; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins | 2008 |
Antimicrobial studies with the Pseudomonas aeruginosa two-allele library require caution.
Topics: Alleles; DNA Transposable Elements; DNA, Bacterial; Drug Resistance, Bacterial; Gene Library; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pyocyanine | 2008 |
A plasmid-borne blaOXA-58 gene confers imipenem resistance to Acinetobacter baumannii isolates from a Lebanese hospital.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Conjugation, Genetic; Cross Infection; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Hospitals, University; Humans; Imipenem; Lebanon; Molecular Epidemiology; Molecular Sequence Data; Plasmids | 2008 |
Genetic basis of multidrug resistance in Acinetobacter baumannii clinical isolates at a tertiary medical center in Pennsylvania.
Topics: Academic Medical Centers; Acinetobacter baumannii; Acinetobacter Infections; Amikacin; Base Sequence; beta-Lactamases; Cross Infection; DNA Primers; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Epidemiology; Pennsylvania; Polymerase Chain Reaction | 2008 |
High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China.
Topics: Acetyltransferases; Anti-Bacterial Agents; Bacterial Proteins; China; Conjugation, Genetic; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Hospitals, Teaching; Humans; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Prevalence; Quinolones | 2008 |
First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy.
Topics: Base Sequence; beta-Lactam Resistance; beta-Lactamases; Data Collection; DNA Primers; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Integrons; Italy; Molecular Epidemiology; Molecular Sequence Data | 2008 |
Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates.
Topics: Anti-Bacterial Agents; beta-Lactamases; Conjugation, Genetic; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Escherichia coli; Humans; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA; Transformation, Bacterial | 2008 |
KPC-2-producing Enterobacter cloacae and pseudomonas putida coinfection in a liver transplant recipient.
Topics: Anti-Bacterial Agents; beta-Lactamases; Enterobacter cloacae; Female; Humans; Liver Transplantation; Microbial Sensitivity Tests; Middle Aged; Pseudomonas putida; RNA, Ribosomal, 16S | 2009 |
Widespread dissemination of aminoglycoside resistance genes armA and rmtB in Klebsiella pneumoniae isolates in Taiwan producing CTX-M-type extended-spectrum beta-lactamases.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Blotting, Southern; DNA, Bacterial; Electrophoresis, Gel, Pulsed-Field; Klebsiella pneumoniae; Taiwan | 2009 |
High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals.
Topics: Acetyltransferases; Adolescent; Adult; Aged; Animals; Animals, Domestic; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cambodia; Cephalosporins; China; Conjugation, Genetic; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli Proteins; Female; Humans; Male; Mali; Microbial Sensitivity Tests; Middle Aged; Nasal Cavity; Plasmids; Quinolones; Young Adult | 2009 |
Nationwide survey of CTX-M-type extended-spectrum beta-lactamases among Klebsiella pneumoniae isolates in Slovenian hospitals.
Topics: Anti-Bacterial Agents; beta-Lactamases; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Hospitals; Klebsiella pneumoniae; Microbial Sensitivity Tests; Slovenia | 2009 |
Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog.
Topics: Animals; Anti-Bacterial Agents; Dogs; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Humans; Plasmids; Virulence | 2009 |
Codetection of blaOXA-23-like gene (blaOXA-133) and blaOXA-58 in Acinetobacter radioresistens: report from the SENTRY antimicrobial surveillance program.
Topics: Acinetobacter; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Bacterial; Molecular Sequence Data; Plasmids; Population Surveillance; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic | 2009 |
First report of KPC-2-producing Klebsiella pneumoniae strains in Brazil.
Topics: beta-Lactamases; Brazil; Carbapenems; Klebsiella pneumoniae | 2009 |
Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18).
Topics: Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Humans; India; Microbial Sensitivity Tests; Molecular Sequence Data; Prevalence; Pseudomonas aeruginosa; Ribotyping | 2009 |
Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.
Topics: Anti-Bacterial Agents; Azithromycin; Bacterial Proteins; Biofilms; Cefepime; Cephalosporins; Ciprofloxacin; Cystic Fibrosis; DNA-Binding Proteins; Humans; Membrane Proteins; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; MutS DNA Mismatch-Binding Protein; Pseudomonas aeruginosa; Transcription Factors | 2009 |
blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures.
Topics: Base Sequence; beta-Lactamases; DNA Transposable Elements; Escherichia coli; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction | 2009 |
First organisms with acquired metallo-beta-lactamases (IMP-13, IMP-22, and VIM-2) reported in Austria.
Topics: Austria; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA | 2009 |
New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis.
Topics: Amino Acid Sequence; Anti-Infective Agents; Bacterial Proteins; Base Sequence; Conjugation, Genetic; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Proteus Infections; Proteus mirabilis; Quinolones; Sequence Analysis, DNA | 2009 |
Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; DNA Transposable Elements; Drug Resistance, Bacterial; Hospitals, Urban; Humans; Isoenzymes; Klebsiella Infections; Klebsiella oxytoca; Klebsiella pneumoniae; Microbial Sensitivity Tests; New York City; Plasmids; Transposases | 2009 |
Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactams; Cystic Fibrosis; Gene Expression Regulation, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum | 2009 |
Inactivation of the glycoside hydrolase NagZ attenuates antipseudomonal beta-lactam resistance in Pseudomonas aeruginosa.
Topics: Acetylglucosamine; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Glycoside Hydrolases; Microbial Sensitivity Tests; Oximes; Phenylcarbamates; Pseudomonas aeruginosa | 2009 |
Chromosomal integration of the extended-spectrum beta-lactamase gene blaCTX-M-15 in Salmonella enterica serotype Concord isolates from internationally adopted children.
Topics: Adoption; Adult; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamases; Child, Preschool; Chromosomes, Bacterial; Conjugation, Genetic; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; France; Humans; Infant; Internationality; Microbial Sensitivity Tests; Norway; Plasmids; Salmonella enterica; Salmonella Infections; Serotyping | 2009 |
Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea.
Topics: Acetyltransferases; beta-Lactamases; Ciprofloxacin; Conjugation, Genetic; Enterobacteriaceae; Microbial Sensitivity Tests; Plasmids | 2009 |
Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system.
Topics: Cystic Fibrosis; DNA Repair; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Neutrophil Activation; Oxidation-Reduction; Oxidative Stress; Pseudomonas aeruginosa | 2009 |
First detection of plasmid-encoded blaOXY beta-lactamase.
Topics: beta-Lactamases; Blotting, Southern; Child, Preschool; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Klebsiella; Klebsiella oxytoca; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction | 2009 |
Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Gene Expression; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Characterization of pABVA01, a plasmid encoding the OXA-24 carbapenemase from Italian isolates of Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Genotype; Microbial Sensitivity Tests; Molecular Sequence Data; Open Reading Frames; Plasmids; Sequence Analysis, DNA | 2009 |
Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007.
Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; China; Drug Resistance, Bacterial; Ertapenem; Escherichia coli; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Imipenem; India; Klebsiella; Quinolones; Thailand | 2009 |
Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria.
Topics: Anti-Bacterial Agents; Azepines; Bacteria, Anaerobic; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests | 2009 |
Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland.
Topics: Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Multiple, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Molecular Sequence Data; Poland | 2009 |
Novel genetic environment of the carbapenem-hydrolyzing beta-lactamase KPC-2 among Enterobacteriaceae in China.
Topics: Anti-Bacterial Agents; beta-Lactamases; Blotting, Southern; Carbapenems; China; Electrophoresis, Gel, Pulsed-Field; Enterobacteriaceae; Microbial Sensitivity Tests; Polymerase Chain Reaction | 2009 |
Involvement of pmrAB and phoPQ in polymyxin B adaptation and inducible resistance in non-cystic fibrosis clinical isolates of Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Genotype; Microbial Sensitivity Tests; Polymyxin B; Promoter Regions, Genetic; Pseudomonas aeruginosa; Transcription Factors | 2009 |
Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone.
Topics: beta-Lactamases; Computational Biology; Escherichia coli; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Plasmids; United Kingdom | 2009 |
Nosocomial spread of colistin-only-sensitive sequence type 235 Pseudomonas aeruginosa isolates producing the extended-spectrum beta-lactamases GES-1 and GES-5 in Spain.
Topics: Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Colistin; Cross Infection; Humans; Molecular Sequence Data; Pseudomonas aeruginosa | 2009 |
Nonclonal emergence of colistin-resistant Klebsiella pneumoniae isolates from blood samples in South Korea.
Topics: Anti-Bacterial Agents; Bacteremia; Colistin; Cross Infection; Drug Resistance, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Population Surveillance; Republic of Korea | 2010 |
Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Carboxylic Ester Hydrolases; Cefotaxime; Cefuroxime; Cephalosporins; Cephalothin; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; India; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2009 |
Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Clavulanic Acid; Gentamicins; Humans; Imipenem; Integrons; Meropenem; Molecular Sequence Data; Penicillanic Acid; Piperacillin; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Spain; Tazobactam; Thienamycins | 2009 |
Role of AbeS, a novel efflux pump of the SMR family of transporters, in resistance to antimicrobial agents in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Multiple, Bacterial; Escherichia coli; Membrane Transport Proteins; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Homology, Amino Acid | 2009 |
In vivo efficacy of 1- and 2-gram human simulated prolonged infusions of doripenem against Pseudomonas aeruginosa.
Topics: Animals; Anti-Bacterial Agents; Carbapenems; Doripenem; Drug Administration Schedule; Female; Humans; Mice; Pseudomonas aeruginosa; Pseudomonas Infections | 2009 |
ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolates.
Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Structure | 2009 |
Susceptibilities of 23 Desulfovibrio isolates from humans.
Topics: Ampicillin; Anti-Bacterial Agents; Chloramphenicol; Clindamycin; Desulfovibrio; Fluoroquinolones; Humans; Metronidazole; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam | 2009 |
Phenotypic and genotypic characterization of Enterobacteriaceae with decreased susceptibility to carbapenems: results from large hospital-based surveillance studies in China.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Carbapenems; China; Cross Infection; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterobacteriaceae; Enterobacteriaceae Infections; Genotype; Integrons; Microbial Sensitivity Tests; Phenotype; Population Surveillance; Porins; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
First isolation of the blaOXA-23 carbapenemase gene from an environmental Acinetobacter baumannii isolate.
Topics: Acinetobacter baumannii; beta-Lactamases; DNA, Bacterial; Escherichia coli; France; Genes, Bacterial; Water Microbiology | 2010 |
Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; DNA, Bacterial; DNA, Complementary; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Genes, MDR; Metals, Heavy; Microbial Sensitivity Tests; Mutation; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Bacterial | 2010 |
Molecular and biochemical characterization of the natural chromosome-encoded class A beta-lactamase from Pseudomonas luteola.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Catheters, Indwelling; Chromosomes, Bacterial; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Genetic Variation; Isoelectric Focusing; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Pseudomonas; Pseudomonas Infections; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity | 2010 |
Molecular epidemiology of metallo-beta-lactamase-producing Pseudomonas aeruginosa isolates from Norway and Sweden shows import of international clones and local clonal expansion.
Topics: Alleles; beta-Lactamases; Conjugation, Genetic; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Microbial Sensitivity Tests; Molecular Epidemiology; Norway; Pseudomonas aeruginosa; Pseudomonas Infections; Serotyping; Sweden | 2010 |
In vitro potency of CXA-101, a novel cephalosporin, against Pseudomonas aeruginosa displaying various resistance phenotypes, including multidrug resistance.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Child; Child, Preschool; Cross Infection; Drug Combinations; Drug Resistance, Multiple, Bacterial; Humans; Infant; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; Young Adult | 2010 |
Activity of a new antipseudomonal cephalosporin, CXA-101 (FR264205), against carbapenem-resistant and multidrug-resistant Pseudomonas aeruginosa clinical strains.
Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Isoelectric Focusing; Microbial Sensitivity Tests; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections | 2010 |
The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability.
Topics: Caco-2 Cells; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Membranes, Artificial; Molecular Structure; Pharmaceutical Preparations | 2010 |
Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Cations, Monovalent; Culture Media; Drug Resistance, Bacterial; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Humans; Microbial Sensitivity Tests; Oligonucleotide Array Sequence Analysis; Proteomics; Sodium Chloride; Virulence Factors | 2010 |
Detection of KPC in Acinetobacter spp. in Puerto Rico.
Topics: Acinetobacter; Acinetobacter Infections; Adult; Aged; Aged, 80 and over; beta-Lactam Resistance; beta-Lactamases; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Population Surveillance; Puerto Rico | 2010 |
Comparative in vitro activities of nemonoxacin (TG-873870), a novel nonfluorinated quinolone, and other quinolones against clinical isolates.
Topics: Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Moxifloxacin; Quinolines; Quinolones; Taiwan | 2010 |
Activity of a new cephalosporin, CXA-101 (FR264205), against beta-lactam-resistant Pseudomonas aeruginosa mutants selected in vitro and after antipseudomonal treatment of intensive care unit patients.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cephalosporins; Cross Infection; Humans; Intensive Care Units; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections | 2010 |
Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients.
Topics: Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Cystic Fibrosis; Drug Resistance, Bacterial; Drug Resistance, Multiple; Electrophoresis, Gel, Pulsed-Field; Humans; Membrane Transport Proteins; Mutation; Porins; Pseudomonas aeruginosa; Pseudomonas Infections; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2010 |
Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Aminoglycosides; beta-Lactamases; Carbapenems; Cephalosporins; DNA Gyrase; Drug Resistance, Bacterial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Taiwan | 2010 |
KPC-producing extreme drug-resistant Klebsiella pneumoniae isolate from a patient with diabetes mellitus and chronic renal failure on hemodialysis in South Korea.
Topics: Aged; beta-Lactamases; Diabetic Nephropathies; Humans; Kidney Failure, Chronic; Klebsiella Infections; Klebsiella pneumoniae; Male; Renal Dialysis; Republic of Korea | 2010 |
Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008.
Topics: Academic Medical Centers; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; DNA Primers; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Infections; Humans; In Vitro Techniques; Israel; Microbial Sensitivity Tests; Molecular Epidemiology; Plasmids; Time Factors | 2010 |
In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli.
Topics: Acinetobacter; Anti-Bacterial Agents; beta-Lactams; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Escherichia coli; Escherichia coli Proteins; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Monobactams; Mutation; Penicillin-Binding Proteins; Phenotype; Pseudomonas aeruginosa; Siderophores; Thiazoles | 2010 |
Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel.
Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Humans; Israel; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Epidemiology; Phylogeny; Plasmids; Polymerase Chain Reaction | 2010 |
Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan.
Topics: Acinetobacter; Acinetobacter Infections; beta-Lactam Resistance; beta-Lactamases; Cephalosporinase; Gene Transfer, Horizontal; Genes, Bacterial; Humans; In Vitro Techniques; Integrons; Microbial Sensitivity Tests; Molecular Epidemiology; Molecular Sequence Data; Phylogeny; Taiwan | 2010 |
In vitro activity of the aminoglycoside antibiotic arbekacin against Acinetobacter baumannii-calcoaceticus isolated from war-wounded patients at Walter Reed Army Medical Center.
Topics: Acinetobacter baumannii; Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Dibekacin; Hospitals, Military; Humans; Microbial Sensitivity Tests; Warfare | 2010 |
Incidence and antimicrobial susceptibility of Escherichia coli and Klebsiella pneumoniae with extended-spectrum beta-lactamases in community- and hospital-associated intra-abdominal infections in Europe: results of the 2008 Study for Monitoring Antimicrob
Topics: Abdomen; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cross Infection; Escherichia coli; Escherichia coli Infections; Humans; Klebsiella Infections; Klebsiella pneumoniae | 2010 |
Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART).
Topics: Abdomen; Amikacin; beta-Lactams; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Ertapenem; Escherichia coli; Gram-Negative Bacteria; Humans; Imipenem; Microbial Sensitivity Tests | 2010 |
First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital.
Topics: Anti-Bacterial Agents; beta-Lactamases; Ceftazidime; Drug Resistance, Bacterial; Germany; Hospitals, University; Humans; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections | 2010 |
The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Burkholderia pseudomallei; Culture Media; Drug Resistance, Multiple, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; Periplasmic Proteins; Quorum Sensing; Singapore; Virulence Factors | 2010 |
Complete nucleotide sequence of Klebsiella pneumoniae multidrug resistance plasmid pKP048, carrying blaKPC-2, blaDHA-1, qnrB4, and armA.
Topics: Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Carbapenems; Cephalosporins; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Klebsiella pneumoniae; Models, Genetic; Molecular Sequence Data; Plasmids | 2010 |
Nationwide investigation of extended-spectrum beta-lactamases, metallo-beta-lactamases, and extended-spectrum oxacillinases produced by ceftazidime-resistant Pseudomonas aeruginosa strains in France.
Topics: Anti-Bacterial Agents; beta-Lactamases; Ceftazidime; Cephalosporin Resistance; France; Humans; Microbial Sensitivity Tests; Prevalence; Pseudomonas aeruginosa; Pseudomonas Infections | 2010 |
Chromosomally encoded blaCMY-2 located on a novel SXT/R391-related integrating conjugative element in a Proteus mirabilis clinical isolate.
Topics: beta-Lactamases; DNA Transposable Elements; DNA, Bacterial; Escherichia coli; Klebsiella pneumoniae; Molecular Sequence Data; Polymerase Chain Reaction; Proteus mirabilis; Salmonella typhimurium | 2010 |
In vitro antimicrobial activity and mutant prevention concentration of colistin against Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Colistin; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests; Mutation | 2010 |
Membrane efflux and influx modulate both multidrug resistance and virulence of Klebsiella pneumoniae in a Caenorhabditis elegans model.
Topics: Animals; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactams; Biological Transport; Caenorhabditis elegans; Drug Resistance, Bacterial; Ertapenem; Klebsiella pneumoniae; Reverse Transcriptase Polymerase Chain Reaction; Virulence | 2010 |
The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Two-Dimensional; Methylmalonate-Semialdehyde Dehydrogenase (Acylating); Microbial Sensitivity Tests; Pseudomonas aeruginosa; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Succinate-Semialdehyde Dehydrogenase | 2010 |
Frequency of spontaneous resistance to fosfomycin combined with different antibiotics in Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Fosfomycin; Mutation; Pseudomonas aeruginosa | 2010 |
Emergence and Distribution of Plasmids Bearing the blaOXA-51-like gene with an upstream ISAba1 in carbapenem-resistant Acinetobacter baumannii isolates in Taiwan.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Blotting, Southern; Carbapenems; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Molecular Sequence Data; Plasmids; Taiwan | 2010 |
Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26.
Topics: Adhesins, Bacterial; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Humans; Plasmids; Shiga Toxins | 2010 |
Outbreak of meropenem-resistant Serratia marcescens comediated by chromosomal AmpC beta-lactamase overproduction and outer membrane protein loss.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Blotting, Southern; Drug Resistance, Bacterial; Female; Humans; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Molecular Sequence Data; Polymerase Chain Reaction; Porins; Reverse Transcriptase Polymerase Chain Reaction; Serratia Infections; Serratia marcescens; Thienamycins; Young Adult | 2010 |
In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Bacterial Proteins; Carbapenems; Drug Resistance, Bacterial; Fatal Outcome; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Potent inhibitors of LpxC for the treatment of Gram-negative infections.
Topics: Amidohydrolases; Animals; Anti-Bacterial Agents; Biphenyl Compounds; Catalytic Domain; Crystallography, X-Ray; Drug Resistance, Bacterial; Hydrogen Bonding; Hydroxamic Acids; Mice; Models, Molecular; Molecular Conformation; Phenyl Ethers; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Stereoisomerism; Structure-Activity Relationship; Sulfides; Sulfones | 2012 |
Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics.
Topics: Anti-Bacterial Agents; beta-Lactams; Computational Biology; Drug Resistance, Bacterial; Hydrophobic and Hydrophilic Interactions; Ligands; Membrane Transport Proteins; Microbial Sensitivity Tests; Models, Molecular; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Regression Analysis; Thermodynamics | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria.
Topics: Anti-Infective Agents; Bacterial Infections; Drug Resistance, Multiple; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Imidazoles; Microbial Sensitivity Tests; Mycoses; Oximes | 2013 |
Hybrid Antibiotic Overcomes Resistance in P. aeruginosa by Enhancing Outer Membrane Penetration and Reducing Efflux.
Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Moxifloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 2016 |
Synthesis, in vitro anticancer and antibacterial activities and in silico studies of new 4-substituted 1,2,3-triazole-coumarin hybrids.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Bacteria; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Computer Simulation; Coumarins; Drug Design; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Structure-Activity Relationship; Triazoles | 2016 |
New amphiphilic neamine conjugates bearing a metal binding motif active against MDR E. aerogenes Gram-negative bacteria.
Topics: Anti-Bacterial Agents; Cell Membrane Permeability; Cephalosporins; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Enterobacter aerogenes; Escherichia coli; Framycetin; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Organometallic Compounds | 2017 |
Novel Design of Heptad Amphiphiles To Enhance Cell Selectivity, Salt Resistance, Antibiofilm Properties and Their Membrane-Disruptive Mechanism.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Biofilms; Circular Dichroism; Drug Design; Hemolysis; Humans; Models, Molecular; Peptides; Protein Structure, Secondary; Pseudomonas aeruginosa; Pseudomonas Infections; Surface-Active Agents | 2017 |
Amphiphilic Tobramycin-Lysine Conjugates Sensitize Multidrug Resistant Gram-Negative Bacteria to Rifampicin and Minocycline.
Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Hemolysis; Lysine; Microbial Sensitivity Tests; Minocycline; Models, Biological; Rifampin; Tobramycin | 2017 |
Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC.
Topics: Amidohydrolases; Animals; Anti-Bacterial Agents; Chemistry Techniques, Synthetic; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Female; Hep G2 Cells; Humans; K562 Cells; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Docking Simulation; Pseudomonas aeruginosa; Pseudomonas Infections; Structure-Activity Relationship | 2017 |
Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae.
Topics: Anti-Bacterial Agents; Colistin; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Escherichia coli; Klebsiella pneumoniae; Microbial Sensitivity Tests; Microwaves; Molecular Structure; Peptide Nucleic Acids; Peptides; Solid-Phase Synthesis Techniques; Structure-Activity Relationship; Tigecycline | 2019 |
Design of Trp-Rich Dodecapeptides with Broad-Spectrum Antimicrobial Potency and Membrane-Disruptive Mechanism.
Topics: Anti-Infective Agents; Antimicrobial Cationic Peptides; Bacterial Outer Membrane; Drug Design; Escherichia coli; Humans; Microbial Sensitivity Tests; Oligopeptides; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Staphylococcus aureus; Tryptophan | 2019 |
Homodimeric Tobramycin Adjuvant Repurposes Novobiocin as an Effective Antibacterial Agent against Gram-Negative Bacteria.
Topics: Anti-Bacterial Agents; Dimerization; Gram-Negative Bacteria; Novobiocin; Tobramycin | 2019 |
Design, synthesis, and biological evaluation of 3-amino-2-oxazolidinone derivatives as potent quorum-sensing inhibitors of Pseudomonas aeruginosa PAO1.
Topics: Anti-Bacterial Agents; Biofilms; Dose-Response Relationship, Drug; Drug Design; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Pseudomonas aeruginosa; Quorum Sensing; Structure-Activity Relationship | 2020 |
Nitroxoline and its derivatives are potent inhibitors of metallo-β-lactamases.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Nitroquinolines; Recombinant Proteins; Structure-Activity Relationship | 2022 |
LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials.
Topics: Albumins; Anti-Bacterial Agents; Cell Membrane; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Structure-Activity Relationship | 2022 |