ciprofloxacin has been researched along with carbostyril in 727 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (5.50) | 18.7374 |
| 1990's | 306 (42.09) | 18.2507 |
| 2000's | 209 (28.75) | 29.6817 |
| 2010's | 126 (17.33) | 24.3611 |
| 2020's | 46 (6.33) | 2.80 |
| Authors | Studies |
|---|---|
| Blumenthal, RM; Burnham, JC; Guan, L | 1 |
| Philip, E; Stein, GE | 1 |
| Cobbs, CG; Smith, KR | 1 |
| Phillips, EA; Shultz, TR; Tapsall, JW | 1 |
| Debbia, EA; Pesce, A; Schito, GC | 1 |
| García, I; Pascual, A; Perea, EJ | 1 |
| Cox, CE | 1 |
| Drexler, HG; Gignac, SM; Uphoff, CC | 1 |
| Abo-Askar, H; Qadri, SM; Ueno, Y | 1 |
| Almodovar, E; Burns, JJ; Qadri, SM; Rabea, N; Ueno, Y | 1 |
| Barry, AL; Fuchs, PC; Pfaller, MA | 1 |
| Akaniro, JC; Arguedas, AG; Stutman, HR; Vargas, OM | 1 |
| Feistauer, SM; Georgopoulos, A; Georgopoulos, M; Graninger, W; Pfleger, S | 1 |
| Bergogne-Bérézin, E; Joly-Guillou, ML | 1 |
| Arai, S; Gohara, Y; Kawashima, T; Kuwano, K; Matsu-Ura, I | 1 |
| Hornstein, LE | 1 |
| Ganiats, TG; Norcross, WA | 1 |
| Fuhr, U; Granneman, GR; Kinzig, M; Mahr, G; Muth, P; Nickel, P; Patterson, K; Sörgel, F; Stephan, U | 1 |
| Hammerschlag, MR; Hyman, CL; Roblin, PM | 1 |
| Andrews, JM; Cooper, MA; Wise, R | 2 |
| Burnham, JC; Guan, L | 1 |
| Morrissey, I; Smith, JT | 1 |
| Aldridge, KE | 2 |
| Appelbaum, PC; Jacobs, MR; Spangler, SK | 3 |
| Citron, DM; Goldstein, EJ | 1 |
| Azoulay-Dupuis, E; Bauchet, J; Pocidalo, JJ; Vallée, E | 1 |
| Jones, RN | 1 |
| Chan, RK; Cheong, LL; Nadarajah, M | 1 |
| Bailey, EM; Kaatz, GW; Lamp, KC; Rybak, MJ; Seo, SM | 1 |
| Girard, D; Gootz, TD; McGuirk, PR | 1 |
| Erwin, ME; Jones, RN | 1 |
| Carnegie, CM; Lindsay, G; Scorer, HJ | 1 |
| Adler, LP; Bednarczyk, EM; Berridge, MS; Green, JA; Leisure, GP; Little, D; Miraldi, FD; Nelson, AD; Panacek, EA | 1 |
| Aoyama, H; Fukuda, H; Hirai, K; Hosaka, M; Tomizawa, H; Yasue, T | 1 |
| Mitsuhashi, S; Wakebe, H | 1 |
| Bornigia, S; De Sio, G; Morbiducci, V; Piersimoni, C; Scalise, G | 1 |
| Azoulay-Dupuis, E; Bauchet, J; Bedos, JP; Pocidalo, JJ; Vallee, E; Veber, B | 1 |
| Jabarit-Aldighieri, N; Raoult, D; Torres, H | 1 |
| Bartlett, RC; Mazens-Sullivan, MF; McCarter, YS | 1 |
| Bouzard, D; Di Cesare, P; Fung-Tomc, J; Hoffmann, P; Kessler, R | 1 |
| Liu, YN; Sun, XD; Wang, R; Zhao, HZ | 1 |
| Farahat, HG; Koutsandrea, CN; Miceli, MV; Niesman, MR; Peyman, GA | 1 |
| LeBel, M; Parent, M | 1 |
| Gootz, TD; Martin, BA | 1 |
| Bollet, C; de Micco, P; Gevaudan, MJ; Mallet, MN | 1 |
| Forstall, GJ; Knapp, CC; Washington, JA | 1 |
| Bethune, L; King, A; Phillips, I | 2 |
| Chin, NX; Neu, HC | 2 |
| Bailey, DL; Epling, GA; Kiely, JS; Robertson, DG; Song, B | 1 |
| Chodosh, S | 2 |
| Hashmi, ZS; Smith, JM | 1 |
| Davey, PG | 1 |
| Jungkind, DL; Parish, LC | 1 |
| Hardy, DJ | 2 |
| Fuchs, PC | 1 |
| Giardina, WJ | 1 |
| Kinzig, M; Mahr, G; Muth, P; Naber, KG; Sorgel, F | 1 |
| Wise, R | 1 |
| Aucoin, DP; Flammer, K; Whitt, DA | 1 |
| Hall, MC; Piddock, LJ; Walters, RN | 1 |
| Barry, AL; Fuchs, PC | 3 |
| Azoulay-Dupuis, E; Bergogne-Bérézin, E; Pocidalo, JJ; Vallée, E | 1 |
| Andrews, JM; Baldwin, DR; Honeybourne, D; Wise, R | 1 |
| Kosmidis, J | 1 |
| Baltch, AL; Louie, A; Ritz, WJ; Smith, RP | 1 |
| Conejo, MC; García, I; Pascual, A; Perea, EJ | 1 |
| Pattyn, SR | 1 |
| Nishino, T; Okamoto, S; Okuda, J; Takahata, M | 1 |
| Piddock, LJ; Zhu, M | 1 |
| Aubert, G; Dorche, G; Pozzetto, B | 2 |
| Inoue, Y; Ito, K; Kotera, Y; Ohashi, M; Tsukamoto, G | 1 |
| Kimura, K; Kise, M; Kitano, M; Matsuda, M; Nishino, T; Otsuki, M; Ozaki, M; Segawa, J; Shibata, K; Tomii, Y | 1 |
| Gocke, E | 1 |
| Adler, LP; Bednarczyk, EM; Berridge, MS; Green, JA; Leisure, GA; Little, D; Miraldi, FD; Nelson, AD; Panacek, EA | 1 |
| Azoulay-Dupuis, E; Bedos, JP; Hardy, DJ; Pocidalo, JJ; Swanson, RN; Vallée, E | 1 |
| Chu, DT; Clement, JJ; Hardy, DJ; Shipkowitz, NL; Swanson, RN | 1 |
| Esteve, M; Gargallo-Viola, D; Guinea, J; Llovera, S; Roca, X | 1 |
| Andrews, JM; Ashby, JP; Cooper, MA; Matthews, RS; Wise, R | 1 |
| McDonald, PJ; Pruul, H | 1 |
| Heifets, LB; Lindholm-Levy, PJ | 1 |
| Allen, RA; Amyes, SG; Lewin, CS | 1 |
| Borsa-Lebas, F; Dhib, M; Fillastre, JP; Humbert, G; Leroy, A; Moulin, B | 1 |
| Albrecht, HA; Beskid, G; Chan, KK; Christenson, JG; Cleeland, R; Deitcher, KH; Georgopapadakou, NH; Keith, DD; Pruess, DL; Sepinwall, J | 1 |
| Bailly, S; Fay, M; Ferrua, B; Gougerot-Pocidalo, MA; Mahe, Y; Tursz, T; Wakasugi, H | 1 |
| Gemeinhardt, A; Janssen, U; Klotz, U; Unseld, E; Ziegler, G | 1 |
| Hall, MC; Piddock, LJ; Wise, R | 1 |
| Hill, JM; Hobden, JA; Insler, MS; O'Callaghan, RJ; Reidy, JJ | 1 |
| Barnett, G; Carbó, M; de la Torre, R; Segura, J | 1 |
| Bodey, GP; Ho, DH; LeBlanc, B; Rolston, KV | 1 |
| Amyes, SG; Barnes, AC; Hastings, TS; Lewin, CS | 1 |
| Bauer, JF; Elrod, L; Fornnarino, JR; Heathcote, DE; Krogh, SK; Linton, CL; Norris, BJ; Quick, JE | 1 |
| Prescott, JF; Yielding, KM | 1 |
| Bryan, JP; Krieg, RE; Perine, PL; Sheffield, J; Wagner, K; Waters, C | 1 |
| Atkinson, HC; Begg, EJ; Frampton, CM; Robson, RA; Saunders, DA | 1 |
| Matsumoto, F; Morita, M; Takahashi, T | 1 |
| García Sánchez, JE; García-Rodríguez, JA; Muñoz Bellido, JL; Trujillano, I | 1 |
| Bhattacharya, SS; Lal, HM; Lalitha, MK; Nisha, AK; Ramamoorthy, U | 1 |
| Clarke, AM; Zemcov, SJ | 1 |
| Greenwood, D; Kanematsu, M | 1 |
| Jehl, F; Koechlin, C; Linger, L; Monteil, H | 1 |
| Allen, W; Gorzynski, EA; Gutman, SI | 1 |
| Andersson, J; Forsgren, A; Gullberg, M; Riesbeck, K | 1 |
| Chapman, JS; Georgopapadakou, NH | 1 |
| Bergan, T | 1 |
| Aronson, AL; Aucoin, DP; Hedeen, KM; Tyczkowska, K | 1 |
| Kotera, Y; Mitsuhashi, S | 1 |
| Arakawa, S; Fujii, A; Kamidono, S; Maeda, H; Nakata, K | 1 |
| Beer, C; Harder, S; Papenburg, A; Shah, PM; Staib, AH; Stille, W | 1 |
| Rehavi, M; Rubinstein, E; Segev, S | 1 |
| Höffler, U | 1 |
| Benonisen, E; Dibb, WL; Digranes, A | 1 |
| Felmingham, D; Grüneberg, RN; O'Hare, MD; Ridgway, GL | 2 |
| Cremer, AW; Felmingham, D; Grüneberg, RN; O'Hare, MD; Ridgway, GL; Robbins, MJ; Wall, RA; Williams, AH | 1 |
| Chin, NX; Figueredo, VM; Neu, HC; Novelli, A | 1 |
| Andrews, JM; Ashby, JP; Matthews, RS; Wise, R | 1 |
| Coll, R; Esteve, M; Gargallo, D; Guinea, J; Moros, M; Parés, J; Xicota, MA | 1 |
| Bebear, C; de Barbeyrac, B; Quentin, C; Renaudin, H | 1 |
| Bodey, GP; Gooch, G; Ho, DH; LeBlanc, B; Rolston, KV | 1 |
| Fernandes, PB; Swanson, RN | 1 |
| Nagayama, A; Nakao, T; Taen, H | 1 |
| Kent, AF; Speller, DC | 1 |
| Oliva, B; Ravagnan, G; Renzini, G; Selan, L | 1 |
| Chin, NX; Neu, HC; Novelli, A | 1 |
| Dohtsu, Y; Hara, K; Hayashi, T; Hirota, M; Koga, H; Kohno, S; Saito, A; Yamaguchi, K | 1 |
| Nishino, T; Obana, Y | 1 |
| Finch, R; Martin, J; Pilkington, R | 1 |
| Clark, JK; Manzella, JP | 1 |
| Bower, RR; Chu, DT; Fernandes, PB; Hanson, CW; Hardy, DJ; Hensey, DM; Ramer, NR; Swanson, RN | 1 |
| Coll, R; Esteve, M; Moros, M; Parés, J; Xicota, MA | 2 |
| Oriel, JD | 1 |
| Smith, JT | 2 |
| Gabriel, FG; Mumtaz, G; Oriel, JD; Ridgway, GL | 1 |
| Peeters, M; Piot, P; Van Dyck, E | 1 |
| Dørflinger, T; Frimodt-Møller, PC; Madsen, PO | 1 |
| Cagni, A; Chuard, C; Lew, DP; Schrenzel, J; Vaudaux, PE | 1 |
| Carlyn, CJ; Doyle, LJ; Knapp, CC; Ludwig, MD; Washington, JA | 1 |
| Khac, SB; Moreau, NJ | 1 |
| Johnson, DM; Jones, RN | 1 |
| Gensberg, K; Jin, YF; Piddock, LJ | 1 |
| Bauernfeind, A | 2 |
| Koeppe, P; Lode, H; Rost, KL; Schaberg, T; Stuht, H | 1 |
| Horsberg, TE; Martinsen, B | 1 |
| Arcidiacono, MM; Fraschini, F; Gattei, G; Mezzetti, M; Scaglione, F | 1 |
| Datsenko, BM; Tamm, TI | 1 |
| Carbon, C; Dautrey, S; Farinoti, R; Ramon, J; Rubinstein, E; St Julien, L | 1 |
| Jones, RN; Sutton, LD | 1 |
| Cantón, E; Pastor, A; Pemán, J | 1 |
| Chauveaux, D; Dehais, J; Le Huec, JC; Le Rebeller, A; Rivel, J; Schaeverbeke, T | 1 |
| Kaatz, GW; Larsson, AJ; Moody, JA; Rotschafer, JC; Walker, KJ; Zabinski, RA | 1 |
| Heilmann, HD; Sirgel, FA; Venter, A | 1 |
| Avril, JL; Donnio, PY; Gastine, C; Travert, MF | 1 |
| Bach, D; Cesana, M; Hübner, A; Plétan, Y; van Breukelen, G; van den Berg-Segers, A | 1 |
| Bradley, SF; Harrington, GD; Kauffman, CA; Ramsey, MA; Zarins, LT | 1 |
| Beskid, G; Prosser, BL | 2 |
| Cooper, B; Freeman, C; Mazens-Sullivan, M; Nightingale, C; Quintiliani, R; Robinson, A | 1 |
| Cormican, MG; Jones, RN; Marshall, SA | 1 |
| Küng, K; Wanner, M | 1 |
| Abadía, AR; Aramayona, JJ; Bregante, MA; Fraile, LJ; Garcia, MA | 1 |
| Appelbaum, PC; Jacobs, MR; Pankuch, GA | 2 |
| Sanders, CC; Thomson, KS | 2 |
| Allemandi, DA; Alovero, FL; Manzo, RH | 1 |
| Anderson, KL; Papich, MG; Tyczkowska, KL; Voyksner, RD | 1 |
| Aoki, M; Goldstein, E; Kunii, O; Ono, Y | 1 |
| Arduino, RC; Frosolono, M; Murray, BE | 1 |
| Gomez, RB; Gracia, MI; Ruiz-Ramirez, L; Sumano, LH | 1 |
| Cid, D; de la Fuente, R; Garcia, S; Piriz, S; Ruiz-Santa-Quiteria, JA; Vadillo, S; Valle, J | 1 |
| el-Kersh, TA; Ramadan, MA; Shibl, AM; Tawfik, AF | 1 |
| Kasatkina, IV; Lozovoĭ, NV; Pasiukov, VV; Shcherbaniuk, AI | 1 |
| D'iakov, SI; Katsalukha, VV; Lebedeva, IK; Lukashina, AV; Raĭskaia, VA | 1 |
| Anderson, MR; Brighty, KE; Castaldi, MJ; Gootz, TD; Haskell, SL; McGuirk, PR; Schmieder, BJ; Sutcliffe, JA | 1 |
| Cherubin, CE; Stratton, CW | 1 |
| Korten, V; Murray, BE; Tomayko, JF | 1 |
| Fujita, H; Matsuo, I | 1 |
| Griggs, DJ; Hall, MC; Jin, YF; Piddock, LJ | 1 |
| Fresnadillo, MJ; García García, MI; García Sánchez, E; García Sánchez, JE; García-Rodríguez, JA; Trujillano, I | 1 |
| Amador, C; Ena, J; Martinez, C; Ortiz de la Tabla, V | 1 |
| Dutov, VV; Kalinin, VN; Nasonov, VN; Nekhorosheva, AG; Rusanova, EV; Savitskaia, KI; Shanina, AG; Solodilova, OE; Trapeznikova, MF | 1 |
| Forsgren, A; Riesbeck, K | 1 |
| Blanco, MT; Gómez-García, AC; Hurtado, C; Morán, FJ; Pérez-Giraldo, C; Rodríguez-Benito, A | 1 |
| Davidson, GW; Yu, X; Zipp, GL | 1 |
| Drexler, HG; Fleckenstein, E; Gignac, SM; Hopert, A; Hu, ZB; Uphoff, CC; Voges, M | 1 |
| Charter, M; Davey, PG; Freeman, A; Jacobson, I; Kelly, S; Lambert, J; Precious, E; Varma, TR | 1 |
| Martínez-Martínez, L; Ortega, MC; Perea, EJ; Suárez, AI | 1 |
| Borobio, MV; Conejo, M; Perea, EJ; Ramirez, E; Suarez, AI | 1 |
| Ammendola, D; De Sarro, A; De Sarro, G; Gareri, P; Juliano, M | 1 |
| Küng, K; Riond, JL; Wanner, M | 1 |
| Allen, SD; Erwin, ME; Gerlach, EH; Jones, RN; Marshall, SA; Murray, PR; Washington, JA | 1 |
| Chuah, SK; Gollapudi, SV; Harvey, T; Thadepalli, H; Thadepalli, HD | 1 |
| Phillips, I; Power, EG | 1 |
| Croizé, J; Le Noc, D; Le Noc, P | 1 |
| Akashi, A; Arai, S; Furudera, T; Gohara, Y; Kuwano, K; Matsubara, S; Matumoto, M; Tseng, CC | 1 |
| Belliveau, P; Crowe, H; Gousee, G; Nightingale, CH; Quintiliani, R | 1 |
| Neumann, T; Patton, M; Reichart, C; Zenilman, JM | 1 |
| Krinke, AJ; Moody, JA; Rotschafer, JC; Vance-Bryan, K; Walker, KJ; Zabinski, RA | 1 |
| Andrews, JM; Baldwin, DR; Gill, M; Honeybourne, D; Wise, R | 1 |
| Ahlén, S; Malmborg, AS | 1 |
| Foleno, BD; Fu, KP; Lafredo, SC | 1 |
| Andrews, JM; Brenwald, N; Wise, R | 2 |
| Akashi, A; Arai, S; Gohara, Y; Kuwano, K; Nishimoto, M; Oizumi, K; Takeda, K; Yamaguchi, T; Yano, T | 1 |
| Küng, K; Riond, JL; Wanner, M; Wolffram, S | 1 |
| Mitsuhashi, S; Yoshida, T | 1 |
| Coll, R; Esteve, M; Garcia, J; Gargallo-Viola, D; Guinea, J; Pares, M; Robert, M; Roser, R; Tudela, E; Xicota, MA | 1 |
| Beumer, H; Hoepelman, AI; Rozenberg-Arska, M; Verhoef, J; Visser, MR | 1 |
| Brumfitt, W; Hamilton-Miller, JM | 1 |
| Ikerd, TR; Koletar, SL | 1 |
| Babish, JG; Vancutsem, PM | 1 |
| Amsterdam, D; Beam, TR; Gorzynski, EA; Mandell, LA; Rotstein, C | 1 |
| Hendrickx, AG; Hummler, H; Richter, WF | 1 |
| Cozzarelli, NR; Khodursky, AB; Zechiedrich, EL | 1 |
| Coll, R; Mirelis, B; Miró, E; Navarro, F; Prats, G; Xicota, MA | 1 |
| Gollapudi, S; Gupta, S; Kim, CH; Thadepalli, F | 1 |
| Dalhoff, A | 1 |
| Berche, P; Gaillot, O | 1 |
| Molinari, G; Schito, GC | 1 |
| Cecchetti, V; Fravolini, A; Pagella, PG; Tabarrini, O; Wise, R | 1 |
| Barlow, D; Gianotti, B; Jean, C; Moi, H; Morel, P; Phillips, I | 2 |
| Eiseman, IA; McGuire, NM; Tack, KJ | 1 |
| Branstetter, DG; Hampton, LA; Linseman, DA | 1 |
| Hale, JA; Knapp, JS; Neal, SW; Rice, RJ; Whittington, WL; Wintersheid, K | 1 |
| Alli, L; Kaartinen, L; Pyörälä, S; Salonen, M | 1 |
| Asaoka, T; Imamori, K; Maebashi, K; Matsuda, H; Matsumoto, M; Tahara, Y | 1 |
| Chen, CR; Drlica, K; Malik, M; Snyder, M | 1 |
| Appelbaum, PC; Jacobs, MR; Visalli, MA | 1 |
| Iakovlev, SV; Iakovlev, VP; Izotova, GN | 1 |
| Curry, PT; Fiedler, RD; Garvin, JR; Kropko, ML; Theiss, JC | 1 |
| Abadía, AR; Aramayona, JJ; Bregante, MA; Fraile, LJ; García, MA; Mora, J | 1 |
| Ibuki, E; Masuda, N; Miyoshi, H; Nishino, T; Otsuki, M; Takahashi, Y | 1 |
| Cheung, MM; Ho, NK; Kam, KM; Wong, PW | 1 |
| di Silverio, F; Geddes, A; Guibert, J; Naber, KG | 1 |
| Amyes, SG; Brown, JC; Jesudason, MV; Shanahan, PM; Thomson, CJ | 1 |
| Bertini, S; Intorre, L; Mengozzi, G; Soldani, G | 1 |
| Bartoletti, R; Pisani, E; Rizzo, M; Trinchieri, A | 1 |
| Fang, W; Jalakas, M; Klaassen, M; Malbe, M; Oöpik, T; Salonen, M; Sandholm, M | 1 |
| Ocampo, L; Sumano, H | 1 |
| Abdulla, AM | 1 |
| Chilima, BZ; Okazawa, Y; Tanno, K; Tosaka, M; Yamane, N | 1 |
| Hayakawa, I; Hohmura, M; Hoshino, K; Ishida, H; Kitamura, A; Nishino, T; Sato, K; Tanaka, M | 1 |
| Chambers, HF; Hackbarth, CJ; Kocagöz, T; Nikaido, H; Rosenberg, EY; Unsal, I | 1 |
| Honmura, T; Komori, K; Matsuda, M; Nishimura, I; Nishino, T; Ozaki, M; Tomii, Y; Yamaguchi, R | 1 |
| Landor, M; Lashinsky, A; Waxman, J | 1 |
| Aoun, M; Crokaert, F; Duchateau, V; Grenier, P; Klastersky, J; Vandermies, A | 1 |
| Breilh, D; Celerier, C; Dorian, M; Grellet, J; Leng, B; Pellegrin, JL; Rispal, P; Saux, MC | 1 |
| Albertini, S; Chételat, AA; Gocke, E | 1 |
| Conejo, MC; García, I; Pascual, A; Perea, EJ; Salvador, J | 1 |
| Kunichan, AD; Mozhokina, GN; Shapatava, MN | 1 |
| Erdem, I; Korten, V; Murray, BE | 1 |
| Bergogne-Bérézin, E; Houot, S; Joly-Guillou, ML; Moreau, NJ | 1 |
| Bagliacca, M; Bertini, S; Intorre, L; Luchetti, E; Mengozzi, G; Soldani, G | 1 |
| Burden, DA; Elsea, SH; Lomenick, JP; Osheroff, N; Westergaard, M | 1 |
| Chida, K; Hayakawa, H; Iwata, M; Kitazawa, H; Sato, A | 1 |
| Dever, JA; Sesnie, JC; Shapiro, MA; VanderRoest, SR | 1 |
| Hof, H; Nichterlein, T; Walz, A | 1 |
| Klecak, G; Urbach, F; Urwyler, H | 1 |
| Forbes, PD; Mäkinen, M; Stenbäck, F | 1 |
| Davies, BI; Dirks-Go, SI; Hoogkamp-Korstanje, JA; Kabel, P; Manson, WL; Stobberingh, EE; Vreede, RW | 1 |
| Anan'eva, LP; Belov, BS; Nasonova, VA; Shubin, SV; Soldatova, SI; Tarasova, GM; Urumova, MM; Ushakova, MA | 1 |
| Fabian, I; Gruss, T; Kletter, Y; Shalit, I; Weiss, K | 1 |
| Gutmann, L; Janoir, C; Kitzis, MD; Moreau, NJ; Zeller, V | 2 |
| Andrews, JM; Boswell, F; Brenwald, NP; Wise, R | 1 |
| Choi, EC; Choi, KH; Hong, JS; Kim, SK; Lee, DK; Yoon, SJ | 1 |
| Barry, AL; Brown, SD; Fuchs, PC | 2 |
| Citron, DM; Goldstein, EJ; Hudspeth, M; Hunt Gerardo, S; Merriam, CV | 1 |
| Borner, K; Koeppe, P; Lode, H; Schaberg, T; Schüler, P; Zemper, K | 1 |
| Gyrd-Hansen, N; Nielsen, P | 1 |
| Arakane, K; Hirobe, M; Mashiko, S; Nagano, T; Ryu, A; Umezawa, N | 1 |
| Chen, D; Prahalad, AK; Rosen, JE; Schlüter, G; Williams, GM | 1 |
| Morrissey, I | 1 |
| George, J; Morrissey, I | 1 |
| Dvorak, T; Ho, DH; LeBlanc, B; Rolston, KV; Streeter, H | 1 |
| Jacobson, ER; Papich, MG; Schumacher, J; Young, LA | 1 |
| Cohen, MA; Gage, JW; Gracheck, SJ; Huband, MD; Roland, GE; Yoder, SL | 1 |
| Cohen, MA; Huband, MD | 1 |
| Kaartinen, L; Panu, S; Pyörälä, S | 1 |
| Choi, EC; Kang, JA; Kim, BK; Kim, JH; Kim, JW; Kim, YG; Lee, JH | 1 |
| Hoogkamp-Korstanje, JA | 1 |
| Cester, CC; Toutain, PL | 1 |
| Dasgupta, MK; Larabie, M; Micetich, RG; Salama, S; Shishido, H; Singh, R | 1 |
| Bornitz, F; Hof, H; Kretschmar, M; Nichterlein, T | 1 |
| Jones, RN; Pfaller, MA | 1 |
| Abadía, AR; Aramayona, JJ; Bregante, MA; Fraile, LJ; García, MA; Martinez, C | 1 |
| Kaartinen, L; Moilanen, M; Pyörälä, S; Räisänen, S | 1 |
| Breisch, S; Chodosh, S; Lakshminarayan, S; Swarz, H | 1 |
| Goldsmith, CE; Moore, JE; Murphy, PG | 1 |
| Andrews, JM; Wise, R | 1 |
| Dawe, R; Ferguson, J | 1 |
| Kan, CA | 1 |
| Choi, EC; Choi, KH; Kim, BK; Kim, JH; Kim, JW; Lee, JH | 1 |
| Kawada, A; Kimura, M | 1 |
| Desaty, TM; Griffin, TJ; Heifetz, CL; Sesnie, JC; Shapiro, MA | 1 |
| Deguchi, T; Kawada, Y; Maeda, SI; Saito, I; Yasuda, M | 1 |
| Hoban, DJ; Karlowsky, JA; Zhanel, GG | 1 |
| Azoulay-Dupuis, E; Bédos, JP; Moine, P; Muffat-Joly, M; Pocidalo, JJ; Vallée, E; Veber, B | 1 |
| Dalhoff, A; Hoppe, JE; Pfründer, D | 1 |
| Gesbert, F; Guittet, M; Kempf, I; van den Hoven, R | 1 |
| Cohen, MA; Gage, JW; Huband, MD; Roland, GE; Yoder, SL | 1 |
| Al-Nawas, B; Shah, PM | 1 |
| Baumann-Wilschke, I; Förster, C; Rücker, M; Shakibaei, M; Stahlmann, R; Vormann, J | 1 |
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| Bao, QY; Chen, XJ; Luo, XH; Zhao, YJ; Zhou, MM; Zhou, TL | 1 |
| Borja Segade, J; Castro Jiménez, A; Feo Brito, FJ; Galindo Bonilla, PA; García Rodríguez, R; Gómez Torrijos, E; Lara de la Rosa, P | 1 |
| Cui, S; Han, L; Luo, Y; Wang, W; Yang, J | 1 |
| Cui, S; Hu, C; Jin, S; Li, J; Lin, L; Luo, Y; Ma, Y; Yang, J; Ye, L; Zhao, Q | 1 |
| Doherty, L; McMullan, R; Millar, G; Smyth, ET; Troughton, JA | 1 |
| Docobo-Pérez, F; Domínguez-Herrera, J; López-Rojas, R; Pachón, J; Sánchez-Céspedes, J; Vila, J | 1 |
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| Cai, JC; Chen, GX; Hu, YY; Sun, Q; Zhang, R; Zhou, HW | 1 |
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| Cheng, J; Hu, LF; Li, JB; Yang, HF; Ye, Y | 1 |
| Camargo, IL; Lima-Bittencourt, CI; Nardi, RM; Nascimento, AM; Paiva, MC | 1 |
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| Aldred, KJ; Kerns, RJ; McPherson, SA; Osheroff, N; Turnbough, CL | 1 |
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| Wasyl, D | 1 |
| Ding, X; Liang, W; Sun, Y; Xiong, W; Zeng, Z; Zhang, Y; Zhong, X | 1 |
| He, W; Huo, X; Li, S; Li, Z; Ma, C; Song, X; Tian, J; Wei, W | 1 |
| Cantón, R; Espinal, P; Garcia-Alonso, F; Gargallo-Viola, D; López, Y; Tato, M; Vila, J | 1 |
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| Jia, H; Li, B; Li, Y; Liu, K; Ma, L; Ma, Z; Qiu, Y; Shao, D; Shi, Y; Wei, J | 1 |
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| Cheng, G; Jiang, W; Kong, L; Lei, C; Liu, B; Shi, H; Wang, H; Wang, Y; Yang, X; Yang, Y; Zhang, A; Zhang, X | 1 |
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| Cha, SY; Choi, SW; Jang, HK; Kang, M; Wei, B | 1 |
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| Correia, DR; Domingues, FC; Ferreira, S; Oleastro, M | 1 |
| Duan, M; Gu, J; Guo, A; Sun, W; Sun, Y; Tuo, X; Wang, X; Yin, Y; Zhang, L | 1 |
| Fang, G; Gao, J; Gao, X; Li, J; Liu, H; Liu, X; Lu, X; Tang, Y; Wang, J | 1 |
| Cullen, M; Heward, E; Hobson, J | 1 |
| Cassiolato, AP; Corso, A; de Moraes, C; Gagetti, P; Gorla, MC; Lemos, AP; Pinhata, JMW | 1 |
| Campos-García, J; Chávez-Jacobo, VM; García-Merinos, JP; Gutiérrez-Corona, JF; Hernández-Ramírez, KC; Meza-Carmen, V; Pérez-Gallardo, RV; Ramírez-Díaz, MI; Romo-Rodríguez, P; Silva-Sánchez, J | 1 |
| Aboshanab, KMA; Ashour, MS; El-Mahallawy, HA; Elkhatib, WF; Hamed, SM; Helmy, MM | 1 |
| Fürnkranz, U; Henrich, B; Walochnik, J | 1 |
| Bicknese, A; Campbell, D; Chen, J; Folster, JP; Karp, BE; McCullough, A; Tagg, K | 1 |
| Butaye, P; Cheng, D; Gong, J; Hathcock, T; Huang, K; Lu, G; Qiu, H; Wang, C; Zhang, J; Zhu, G | 1 |
| Abdalhamid, BA; Alabdulqader, NA; Aljindan, RY; Hassan, HA; Hussein, NE; Khoudair, HA; Shaikh, AY; Shorman, MA | 1 |
| Campioni, F; Costa, RG; Falcão, JP; Fernandes, SA; Gomes, CN; Passaglia, J; Rodrigues, DP; Tiba Casas, MR; Vilela, FP | 1 |
| Abdel-Rahim, MH; Aly, SA; Boothe, DM; Daef, EA; El-Badawy, O; Hadiya, S; Suh, SJ | 1 |
| Lee, YJ; Seo, KW | 2 |
| Ajiboye, TO; Ibitoye, OB | 1 |
| Cho, DY; Lim, DJ; Mackey, C; McCormick, J; Skinner, D; Woodworth, BA; Zhang, S | 1 |
| Cheng, Y; Guo, X; Luo, Q; Shao, H; Wang, G; Wang, H; Wen, G; Zhang, T; Zhang, W | 1 |
| Bogdan, C; Eisenberger, D; Höller, C; Lehner-Reindl, V; Nickel, S; Valenza, G; Werner, M | 1 |
| Agarwal, S; Garg, V; Gebre, A; Han, L; Huang, J; Jiang, L; Lekstrom-Himes, J; Li, C; Robertson, S; Shen, J; Stephan, K; Wang, LT | 1 |
| Cho, DY; Garcia, JAP; Lim, DJ; Mackey, C; McCormick, J; Skinner, D; Weeks, CG; Woodworth, BA; Zhang, S | 1 |
| Bényei, AC; Brabec, V; Buglyó, P; Crlikova, H; Farkas, E; Kasparkova, J; Kozsup, M | 1 |
| Basu, S; Mukherjee, M | 1 |
| Abbasi, E; Ghaznavi-Rad, E; van Belkum, A | 1 |
| Li, G; Li, Y; Wang, X; Xie, Y; Yu, M | 1 |
| Agyepong, N; Allam, M; Amoako, DG; Essack, S; Govinden, U; Janice, J; Owusu-Ofori, A; Pedersen, T; Sundsfjord, A | 1 |
| Hidalgo, AA; Millanao, AR; Mora, AY; Mora, GC; Saavedra, CP; Valenzuela, LM; Villagra, NA | 1 |
| Amado Fernández, E; Losada Castillo, I; Malvar Pintos, A; Paz Montero, Ó; Pousa Ortega, Á; Purriños-Hermida, MJ | 1 |
| Ahn, J; Dawan, J; Ding, T; Kim, B; Kim, JC; Uddin, MJ | 1 |
| Antonelli, PJ; Dirain, CO; Karnani, DN | 1 |
| Li, Y; Wang, X; Zhao, X | 1 |
| Dahanayake, PS; De Silva, BCJ; Heo, GJ; Hossain, S | 1 |
| Khairy, RMM; Kotb, DN; Mahdy, WK; Mahmoud, MS | 1 |
| Bandyopadhyay, B; Giri, N; Roy, B; Tousif Ahamed, SK | 1 |
| Allen, M; Cho, DY; Elder, JB; Grayson, JW; Lim, DJ; McCormick, J; McLemore, JG; Rowe, SM; Skinner, D; West, JM; Woodworth, BA; Zhang, S | 1 |
| Măciucă, AM; Munteanu, AC; Uivarosi, V | 1 |
| Bao, C; Bao, J; Cheng, S; Dong, C; Gu, B; Hong, J; Jin, D; Liu, G; Qian, H; Tan, Z | 1 |
| Lee, Y; Seo, K | 1 |
| Diaz-Diaz, S; Docobo-Pérez, F; Machuca, J; Ortiz-Padilla, M; Pascual, A; Recacha, E; Rodríguez-Martínez, JM; Tejada-Gonzalez, A | 1 |
| Amara, M; Bajolet, O; Benmansour, H; Cambau, E; de Champs, C; Guillard, T; Micaëlo, M; Muggeo, A; Pangon, B | 1 |
| Dhara, L; Tripathi, A | 1 |
| Chen, Y; Gin, KY; Hassan, M; He, Y; Huang, Y; Yang, J; Zhang, B; Zhang, X | 1 |
| Duque-Yemail, J; Grau-López, L; Palma-Alvarez, RF; Perea-Ortueta, M; Ramos-Quiroga, JA; Robles-Martínez, M; Ros-Cucurull, E | 1 |
| Andreassen, V; Blix, HS; Waagsbø, B | 1 |
| Boqvist, S; Emanuelson, U; Fernström, LL; Frosth, S; Hansson, I; Tamminen, LM | 1 |
| Han, S; Li, Y; Ren, J; Ren, Z; Wang, Y; Xu, H | 1 |
| Cabañas, R; Domínguez-Ortega, J; Fiandor, A; González-Muñoz, M; Lluch-Bernal, M; Loli-Ausejo, D; Vílchez-Sánchez, F | 1 |
| Goto, K; Itoh, H; Kai, M; Kitano, T; Ohchi, Y; Suzuki, Y; Tanaka, R; Tatsuta, R; Yasuda, N | 1 |
| Gil-Marqués, ML; Hooper, DC; Jacoby, GA | 1 |
| Chen, C; Hooper, DC; Jacoby, GA; Kim, ES; Nakaminami, H; Wang, Y | 1 |
| Dogan, B; Orhan Kubat, G | 1 |
| ChaoLuMen, Q; Du, X; Lv, Y; Shi, X; Wang, J; Wang, Y; Zhang, J | 1 |
| Babaeekhou, L; Ghane, M; Nabilou, M | 1 |
| Asareh Zadegan Dezfuli, A; Farajzadeh Sheikh, A; Keshavarzi, R; Khani, P; Saki, M; Seyed-Mohammadi, S; Shahin, M; Tabasi, M; Veisi, H | 1 |
| Bjerre, LM; Crispo, JAG; Fortin, Y; Krewski, D; Mattison, D; McNair, D; Momoli, F; Moog, R; Taher, MK | 1 |
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| Hou, W; Jin, J; Wang, H; Xia, H; Yan, N; Zhou, M | 1 |
| Chang, J; He, S; Hu, M; Qin, X; Shi, C; Shi, X; Xu, X; Zhang, Z; Zhou, M | 1 |
| Arques, A; Escudero-Oñate, C; Micó, P; Mora, M; Oller, I; Sciscenko, I | 1 |
| Chen, H; Cui, JS; Fu, Y; Ju, ZJ; Zhang, LL; Zhao, XY | 1 |
| Do, KH; Lee, WK; Seo, K | 1 |
| El Saeed, HS; Elmaaty, AA; Ezz Eldin, RR; Salah, M; Saleh, MA; Saleh, MM | 1 |
| Gunardi, WD; Moehario, LH; Nainggolan, IM; Nathania, I; Nusatia, ACM; Tjoa, E; Yasmon, A | 1 |
| Bai, L; Chen, S; Du, PC; Jia, HY; Lu, M; Wang, Y; Zhai, WS; Zhan, ZF | 1 |
| Bartoletti, R; Cicione, A; DE Nunzio, C; Ficarra, V; Franco, A; Labella, M; Lombardo, R; Nacchia, A; Simonato, A; Trucchi, A; Tubaro, A | 1 |
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| Diakhate, MM; Kariuki, K; Kariuki, S; Musembi, S; Mutuku, E; Mutuma, T; Pavlinac, PB; Rwigi, D; Singa, BO; Soge, OO; Tickell, KD; Tornberg-Belanger, SN; Walson, JL | 1 |
| Feng, Y; Geng, S; Huo, Z; Ma, Y; Shen, F; Wang, Z; Wen, J; Yao, X; Zhou, Y; Zhu, F; Zhu, L | 1 |
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22 review(s) available for ciprofloxacin and carbostyril
| Article | Year |
|---|---|
Meta-analysis of quinolone-theophylline interactions.
Topics: Ciprofloxacin; Drug Interactions; Enoxacin; Humans; Meta-Analysis as Topic; Quinolones; Theophylline | 1991 |
Comparative pharmacokinetics of ciprofloxacin and temafloxacin in humans: a review.
Topics: Aging; Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Fluoroquinolones; Humans; Kidney Diseases; Liver Diseases; Quinolones; Tissue Distribution | 1991 |
Comparative penetration of selected fluoroquinolones into respiratory tract fluids and tissues.
Topics: Anti-Infective Agents; Bronchi; Ciprofloxacin; Epithelium; Fluoroquinolones; Humans; Macrophages, Alveolar; Mucous Membrane; Quinolones; Respiratory System | 1991 |
Use of quinolones for the treatment of acute exacerbations of chronic bronchitis.
Topics: Acute Disease; Anti-Infective Agents; Bronchitis; Chronic Disease; Ciprofloxacin; Fluoroquinolones; Humans; Ofloxacin; Quinolones | 1991 |
Pharmacokinetics of quinolones in renal insufficiency.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Glomerular Filtration Rate; Half-Life; Humans; Kidney Failure, Chronic; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1990 |
Pharmacokinetics of ciprofloxacin with reference to other fluorinated quinolones.
Topics: Ciprofloxacin; Half-Life; Humans; Quinolones | 1989 |
Ciprofloxacin in the treatment of gonorrhoea and non-gonococcal urethritis.
Topics: 4-Quinolones; Anti-Infective Agents; Anti-Infective Agents, Urinary; Chlamydia Infections; Chlamydia trachomatis; Ciprofloxacin; Gonorrhea; Humans; Norfloxacin; Quinolines; Quinolones; Urethritis | 1986 |
Oral ciprofloxacin, ofloxacin, and lomefloxacin as alternatives to intravenous antimicrobial therapy.
Topics: Administration, Oral; Anti-Bacterial Agents; Ciprofloxacin; Drug Costs; Drug Tolerance; Female; Fluoroquinolones; Gram-Negative Aerobic Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Cocci; Humans; Male; Ofloxacin; Quinolones; Treatment Outcome | 1993 |
[Pharmacokinetics of fluoroquinolones in patients with renal insufficiency].
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Ofloxacin; Pefloxacin; Quinolones; Renal Insufficiency | 1995 |
Comparison of single preoperative oral rufloxacin versus perioperative ciprofloxacin as prophylactic agents in transurethral surgery.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Ciprofloxacin; Female; Fluoroquinolones; Humans; Male; Middle Aged; Prospective Studies; Quinolones; Urethra; Urologic Surgical Procedures | 2000 |
Quinolones: a comprehensive review.
Topics: Ciprofloxacin; Drug Interactions; Humans; Male; Prostatitis; Quinolones; Respiratory Tract Diseases; Sexually Transmitted Diseases; Urinary Tract Infections | 2002 |
Antibiotic resistance: learning from animal feeds and animal experimentation.
Topics: Animal Feed; Animals; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; In Vitro Techniques; Methicillin; Models, Animal; Quinolones; Rabbits; Rats; Staphylococcus aureus; Streptococcus | 2001 |
The expanding role of fluoroquinolones.
Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Urinary Tract Infections | 2002 |
Levofloxacin in the treatment of urinary tract infections and prostatitis.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Cross Infection; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Microbial; Female; Fluoroquinolones; Follow-Up Studies; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Prostatitis; Quinolones; Severity of Illness Index; Treatment Outcome; Urinary Tract Infections | 2004 |
Quinolones in dermatology.
Topics: Anti-Infective Agents; Area Under Curve; Bacterial Infections; Biological Availability; Ciprofloxacin; Fluoroquinolones; Humans; Intestinal Absorption; Microbial Sensitivity Tests; Nalidixic Acid; Quinolones; Skin Diseases; Structure-Activity Relationship | 2004 |
Quinolones for treatment of nosocomial pneumonia: a meta-analysis.
Topics: Anti-Infective Agents; Cilastatin; Ciprofloxacin; Cross Infection; Humans; Imipenem; Levofloxacin; Meta-Analysis as Topic; Ofloxacin; Pneumonia, Bacterial; Quinolones; Randomized Controlled Trials as Topic | 2005 |
Mechanisms of resistance to quinolones.
Topics: Ciprofloxacin; DNA Topoisomerase IV; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Mutation; Plasmids; Quinolones; Staphylococcus aureus | 2005 |
Resistance in gram-negative bacteria: enterobacteriaceae.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Carbapenems; Cephalosporins; Ciprofloxacin; Community-Acquired Infections; Drug Resistance, Bacterial; Drug Resistance, Multiple; Enterobacteriaceae; Enterobacteriaceae Infections; Gram-Negative Bacterial Infections; Humans; Klebsiella Infections; Quinolones; Urinary Tract Infections | 2006 |
Quinolones for uncomplicated acute cystitis in women.
Topics: Acute Disease; Adult; Anti-Infective Agents, Urinary; Ciprofloxacin; Cystitis; Female; Fluoroquinolones; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Randomized Controlled Trials as Topic | 2006 |
Quinolone Complexes with Lanthanide Ions: An Insight into their Analytical Applications and Biological Activity.
Topics: Binding Sites; Ciprofloxacin; DNA; DNA Topoisomerase IV; Lanthanoid Series Elements; Quinolones | 2020 |
Quinolone-induced psychosis: an updated review.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Delirium; Humans; Levofloxacin; Ofloxacin; Psychoses, Substance-Induced; Quinolones | 2020 |
Is EMA warning on quinolones and fluoroquinolones really assessed? An EudraVigilance database analysis.
Topics: Ciprofloxacin; Fluoroquinolones; Levofloxacin; Quinolones; Retrospective Studies | 2023 |
42 trial(s) available for ciprofloxacin and carbostyril
| Article | Year |
|---|---|
Comparison of three-day temafloxacin with seven-day ciprofloxacin treatment of urinary tract infections in women.
Topics: Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Female; Fluoroquinolones; Humans; Middle Aged; Quinolones; Urinary Tract Infections | 1992 |
A comparison of the safety and efficacy of lomefloxacin and ciprofloxacin in the treatment of complicated or recurrent urinary tract infections.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Escherichia coli Infections; Female; Fluoroquinolones; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Quinolones; Recurrence; Single-Blind Method; Treatment Outcome; Urinary Tract Infections | 1992 |
Effects of temafloxacin and ciprofloxacin on the pharmacokinetics of caffeine.
Topics: Adult; Anti-Infective Agents; Caffeine; Ciprofloxacin; Double-Blind Method; Drug Interactions; Female; Fluoroquinolones; Humans; Male; Quinolones | 1992 |
Safety and efficacy of temafloxacin versus ciprofloxacin in lower respiratory tract infections: a randomized, double-blind trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteria; Ciprofloxacin; Double-Blind Method; Drug Interactions; Female; Fluoroquinolones; Humans; Male; Middle Aged; Prospective Studies; Quinolones; Respiratory Tract Infections; Theophylline | 1992 |
Comparative assessment of the effect of lomefloxacin, ciprofloxacin, and placebo on cerebral blood flow, and glucose and oxygen metabolism in healthy subjects by positron emission tomography.
Topics: Adolescent; Adult; Anti-Infective Agents; Brain; Cerebrovascular Circulation; Ciprofloxacin; Female; Fluoroquinolones; Glucose; Humans; Male; Oxygen; Quinolones; Tomography, Emission-Computed | 1992 |
Comparison of serum bactericidal activity of 4 fluoroquinolones in healthy volunteers.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Female; Fluoroquinolones; Gram-Positive Cocci; Humans; Male; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Serum Bactericidal Test | 1992 |
Temafloxacin compared with ciprofloxacin in mild to moderate lower respiratory tract infections in ambulatory patients. A multicenter, double-blind, randomized study.
Topics: Ambulatory Care; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Female; Fluoroquinolones; Humans; Lung Diseases, Obstructive; Male; Microbial Sensitivity Tests; Middle Aged; Pneumonia; Quinolones; Respiratory Tract Infections | 1991 |
Efficacy of temafloxacin versus ciprofloxacin or amoxicillin for lower respiratory tract infections in smokers and the elderly.
Topics: Age Factors; Aged; Amoxicillin; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Female; Fluoroquinolones; Humans; Male; Quinolones; Respiratory Tract Infections; Smoking | 1991 |
Systemic antimicrobial therapy in skin and skin structure infections: comparison of temafloxacin and ciprofloxacin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Double-Blind Method; Female; Fluoroquinolones; Humans; Male; Middle Aged; Quinolones; Skin Diseases, Infectious | 1991 |
A double-blind study of once-daily temafloxacin in the treatment of bacterial lower respiratory tract infections.
Topics: Adolescent; Adult; Anti-Infective Agents; Bronchitis; Ciprofloxacin; Double-Blind Method; Female; Fluoroquinolones; Humans; Male; Pneumonia; Quinolones; Respiratory Tract Infections | 1991 |
Comparison of the effect of temafloxacin, ciprofloxacin, or placebo on cerebral blood flow, glucose, and oxygen metabolism in healthy subjects by means of positron emission tomography.
Topics: Adolescent; Adult; Anti-Infective Agents; Brain; Cerebrovascular Circulation; Ciprofloxacin; Deoxyglucose; Double-Blind Method; Fluoroquinolones; Glucose; Humans; Male; Oxygen; Placebos; Prospective Studies; Quinolones; Reference Values; Tomography, Emission-Computed | 1991 |
Comparative effects of ciprofloxacin and lomefloxacin on the oxidative metabolism of theophylline.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Fluoroquinolones; Humans; Male; Oxidation-Reduction; Quinolones; Random Allocation; Theophylline | 1990 |
4-quinolones inhibit biotransformation of caffeine.
Topics: Adult; Biotransformation; Caffeine; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Interactions; Enoxacin; Humans; Male; Molecular Structure; Norfloxacin; Ofloxacin; Pipemidic Acid; Quinolones; Random Allocation; Theophylline | 1988 |
Interaction study of lomefloxacin and ciprofloxacin with omeprazole and comparative pharmacokinetics.
Topics: Adult; Anti-Infective Agents; Biotransformation; Chromatography, High Pressure Liquid; Ciprofloxacin; Double-Blind Method; Drug Interactions; Female; Fluoroquinolones; Half-Life; Humans; Male; Omeprazole; Quinolones | 1995 |
Penetration of pefloxacin and ciprofloxacin into lung tissue.
Topics: 4-Quinolones; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Lung; Male; Middle Aged; Pefloxacin; Quinolones | 1995 |
Rufloxacin once daily versus ciprofloxacin twice daily in the treatment of patients with acute uncomplicated pyelonephritis.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Drug Administration Schedule; Escherichia coli Infections; Female; Fluoroquinolones; Follow-Up Studies; Humans; Male; Middle Aged; Pyelonephritis; Quinolones; Treatment Outcome | 1995 |
[Maxaquin and ciprofloxacin in the treatment of complicated and recurrent urinary infections in adults].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Female; Fluoroquinolones; Humans; Male; Middle Aged; Quinolones; Recurrence; Urinary Tract Infections | 1994 |
Comparative bronchoalveolar concentrations of ciprofloxacin and lomefloxacin following oral administration.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchi; Bronchoalveolar Lavage Fluid; Ciprofloxacin; Female; Fluoroquinolones; Humans; Male; Middle Aged; Mucous Membrane; Quinolones | 1993 |
Efficacy and safety of single oral dose sparfloxacin vs ciprofloxacin in acute gonococcal urethritis in males. A multicentre international study.
Topics: Acute Disease; Adult; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Fluoroquinolones; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Quinolones; Urethritis | 1995 |
Initial clinical experience with clinafloxacin in the treatment of serious infections.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Child; Ciprofloxacin; Drug Resistance, Multiple; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Middle Aged; Quinolones | 1995 |
Comparative efficacy and safety of single oral doses of sparfloxacin versus ciprofloxacin in the treatment of acute gonococcal urethritis in men.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Drug Administration Schedule; Fluoroquinolones; Gonorrhea; Humans; International Cooperation; Male; Middle Aged; Quinolones; Urethritis | 1996 |
Comparative efficacy of sparfloxacin versus ciprofloxacin in the treatment of complicated urinary tract infection.
Topics: Adolescent; Adult; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Escherichia coli Infections; Female; Fluoroquinolones; Humans; International Cooperation; Male; Middle Aged; Quinolones; Urinary Tract Infections | 1996 |
Lomefloxacin versus ciprofloxacin in the treatment of complicated urinary tract infections: a multicenter study.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Escherichia coli; Female; Fluoroquinolones; Humans; Italy; Klebsiella; Male; Middle Aged; Proteus; Pseudomonas; Quinolones; Streptococcus; Treatment Outcome; Urinary Tract Infections | 1996 |
Penetration of sparfloxacin and ciprofloxacin into alveolar macrophages, epithelial lining fluid, and polymorphonuclear leucocytes.
Topics: Anti-Infective Agents; Blood; Bronchoalveolar Lavage Fluid; Ciprofloxacin; Epithelium; Female; Fluoroquinolones; Humans; Leukocytes, Mononuclear; Lung; Macrophages, Alveolar; Male; Microbial Sensitivity Tests; Quinolones | 1997 |
Efficacy and safety of a 10-day course of 400 or 600 milligrams of grepafloxacin once daily for treatment of acute bacterial exacerbations of chronic bronchitis: comparison with a 10-day course of 500 milligrams of ciprofloxacin twice daily.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Bronchodilator Agents; Chronic Disease; Ciprofloxacin; Double-Blind Method; Drug Administration Schedule; Female; Fluoroquinolones; Humans; Male; Middle Aged; Piperazines; Prospective Studies; Quinolones; Theophylline; Treatment Outcome | 1998 |
Phototoxicity in quinolones: comparison of ciprofloxacin and grepafloxacin.
Topics: Adolescent; Adult; Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Double-Blind Method; Drug Administration Schedule; Erythema; Female; Fluoroquinolones; Humans; Male; Middle Aged; Piperazines; Placebos; Quinolones; Reference Standards; Skin Pigmentation; Ultraviolet Rays | 1997 |
[Selection of antibacterial therapy for treatment of infections in elderly patients].
Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Cefaclor; Cephalosporins; Ciprofloxacin; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Male; Quinolones; Respiratory Tract Infections | 1998 |
Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis.
Topics: Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Fluoroquinolones; Follow-Up Studies; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Osteomyelitis; Quinolones | 2000 |
A comparison of the photosensitizing potential of trovafloxacin with that of other quinolones in healthy subjects.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Male; Naphthyridines; Photosensitivity Disorders; Quinolones; Single-Blind Method; Skin; Ultraviolet Rays | 2000 |
Comparison of single preoperative oral rufloxacin versus perioperative ciprofloxacin as prophylactic agents in transurethral surgery.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Ciprofloxacin; Female; Fluoroquinolones; Humans; Male; Middle Aged; Prospective Studies; Quinolones; Urethra; Urologic Surgical Procedures | 2000 |
Comparison of fluoroquinolone pharmacokinetic parameters after treatment with marbofloxacin, enrofloxacin, and difloxacin in dogs.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Cross-Over Studies; Dogs; Enrofloxacin; Female; Fluoroquinolones; Quinolones; Skin | 2000 |
Activity and postantibiotic effect of marbofloxacin, enrofloxacin, difloxacin and ciprofloxacin against feline Bordetella bronchiseptica isolates.
Topics: Animals; Anti-Infective Agents; Bordetella bronchiseptica; Bordetella Infections; Cat Diseases; Cats; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Male; Microbial Sensitivity Tests; Quinolones | 2001 |
Randomized, double-blind study of prulifloxacin versus ciprofloxacin in patients with acute exacerbations of chronic bronchitis.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Ciprofloxacin; Dioxolanes; Double-Blind Method; Female; Fluoroquinolones; Humans; Male; Middle Aged; Piperazines; Quinolones; Treatment Outcome | 2002 |
Lomefloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Fluoroquinolones; Humans; Male; Prostatitis; Pseudomonas; Quinolones; Treatment Outcome; Urinary Tract Infections | 2002 |
Pharmacokinetics of enrofloxacin and its active metabolite ciprofloxacin and its interaction with diclofenac after intravenous administration in buffalo calves.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Buffaloes; Ciprofloxacin; Diclofenac; Drug Interactions; Enrofloxacin; Female; Fluoroquinolones; Injections, Intravenous; Quinolones | 2003 |
Pharmacokinetics of enrofloxacin and its active metabolite ciprofloxacin in cows following single dose intravenous administration.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Cattle; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Injections, Intravenous; Quinolones | 2003 |
Comparison of topical lomefloxacin 0.3 per cent versus topical ciprofloxacin 0.3 per cent for the treatment of presumed bacterial corneal ulcers.
Topics: Administration, Topical; Adolescent; Adult; Anti-Infective Agents; Chi-Square Distribution; Child; Child, Preschool; Ciprofloxacin; Corneal Ulcer; Double-Blind Method; Female; Fluoroquinolones; Humans; Male; Middle Aged; Prospective Studies; Quinolones; Statistics, Nonparametric; Treatment Outcome | 2004 |
Prulifloxacin.
Topics: Administration, Oral; Amoxicillin; Animals; Anti-Bacterial Agents; Bronchitis, Chronic; Ciprofloxacin; Clavulanic Acid; Dioxolanes; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Half-Life; Humans; Italy; Molecular Structure; New Zealand; Pefloxacin; Piperazines; Prodrugs; Quinolones; Urinary Tract Infections | 2004 |
Prulifloxacin versus ciprofloxacin in the treatment of adults with complicated urinary tract infections.
Topics: Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Double-Blind Method; Female; Fluoroquinolones; Humans; Male; Middle Aged; Piperazines; Quinolones; Treatment Outcome; Urinary Tract Infections | 2005 |
Plasma and interstitial fluid pharmacokinetics of enrofloxacin, its metabolite ciprofloxacin, and marbofloxacin after oral administration and a constant rate intravenous infusion in dogs.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Ciprofloxacin; Cross-Over Studies; Dogs; Enrofloxacin; Extracellular Fluid; Female; Fluoroquinolones; Infusions, Intravenous; Quinolones | 2005 |
In vitro evaluation of IgE-mediated hypersensitivity reactions to quinolones.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Aza Compounds; Basophil Degranulation Test; Ciprofloxacin; Female; Fluoroquinolones; Humans; Hypersensitivity, Immediate; Immunologic Tests; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Radioimmunoassay; Sensitivity and Specificity; Young Adult | 2011 |
Pharmacokinetic and Drug-Drug Interaction Profiles of the Combination of Tezacaftor/Ivacaftor.
Topics: Adolescent; Adult; Aminophenols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzodioxoles; Ciprofloxacin; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Indoles; Male; Middle Aged; Quinolones; Young Adult | 2019 |
664 other study(ies) available for ciprofloxacin and carbostyril
| Article | Year |
|---|---|
Analysis of macromolecular biosynthesis to define the quinolone-induced postantibiotic effect in Escherichia coli.
Topics: Anti-Infective Agents; Autoradiography; Bacterial Proteins; Cell Division; Cells, Cultured; Ciprofloxacin; DNA, Bacterial; Enoxacin; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones; RNA, Bacterial | 1992 |
In vitro activity of sparfloxacin and three other fluoroquinolones against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones; Staphylococcus aureus; Staphylococcus epidermidis | 1992 |
Characteristics of Neisseria gonorrhoeae isolated in Australia showing decreased sensitivity to quinolone antibiotics.
Topics: Anti-Bacterial Agents; Australia; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Genetic Variation; Gonorrhea; Humans; Neisseria gonorrhoeae; Quinolones | 1992 |
In vitro assessment of the postantibiotic effect of lomefloxacin against gram-positive and gram-negative pathogens.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Time Factors | 1992 |
Comparative penetration of lomefloxacin and other quinolones into human phagocytes.
Topics: Analysis of Variance; Anti-Infective Agents; Ascitic Fluid; Ciprofloxacin; Fluoroquinolones; Humans; In Vitro Techniques; Macrophages; Neutrophils; Norfloxacin; Ofloxacin; Quinolones | 1992 |
Mycoplasma contamination in human leukemia cell lines. II. Elimination with various antibiotics.
Topics: Anti-Bacterial Agents; Cell Division; Cell Line; Ciprofloxacin; Diterpenes; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Leukemia; Minocycline; Mycoplasma Infections; Quinolones | 1992 |
Antibacterial activity of the new quinolone CI-960 (PD 127391) against clinical isolates at a major tertiary care center in Saudi Arabia.
Topics: Anti-Infective Agents; Ciprofloxacin; Enterobacter cloacae; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Hospitals, Urban; Klebsiella pneumoniae; Microbial Sensitivity Tests; Norfloxacin; Pseudomonas aeruginosa; Quinolones; Saudi Arabia | 1992 |
In vitro activity of sparfloxacin (CI-978), a new broad-spectrum fluoroquinolone.
Topics: Anti-Infective Agents; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Microbial Sensitivity Tests; Norfloxacin; Quinolones | 1992 |
Spontaneously occurring staphylococcal mutants resistant to clinically achievable concentrations of ciprofloxacin and temafloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Quinolones; Staphylococcus aureus; Staphylococcus epidermidis | 1992 |
In vitro activity of sparfloxacin (AT-4140), a new quinolone agent, against invasive isolates from pediatric patients.
Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Infant; Infant, Newborn; Microbial Sensitivity Tests; Mutation; Quinolones | 1992 |
Antibacterial activity of sparfloxacin against experimental renal infections in mice.
Topics: Abscess; Animals; Anti-Infective Agents; Ciprofloxacin; Escherichia coli Infections; Female; Fleroxacin; Fluoroquinolones; Half-Life; Kidney Diseases; Methicillin Resistance; Mice; Quinolones; Staphylococcal Infections | 1992 |
In-vitro activity of sparfloxacin, pefloxacin, ciprofloxacin and temafloxacin against clinical isolates of Acinetobacter spp.
Topics: Acinetobacter; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Pefloxacin; Quinolones | 1992 |
[In vitro antimicrobial activities of new quinolone antibiotics against Mycoplasma pneumoniae].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Macrolides; Mycoplasma pneumoniae; Norfloxacin; Ofloxacin; Quinolones; Tetracyclines | 1992 |
Temafloxacin vs ciprofloxacin for UTI.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Quinolones; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections | 1992 |
Temafloxacin vs ciprofloxacin for UTI.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Quinolones; Urinary Tract Infections | 1992 |
In vitro activities of five quinolones against Chlamydia pneumoniae.
Topics: Anti-Infective Agents; Chlamydophila pneumoniae; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1992 |
In-vitro activity of PD 131628, a new quinolone antimicrobial agent.
Topics: Anti-Infective Agents; Bacteroides fragilis; Ceftazidime; Cefuroxime; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gentamicins; Gram-Positive Bacteria; Haemophilus influenzae; Humans; Imipenem; Microbial Sensitivity Tests; Moraxella catarrhalis; Naphthyridines; Neisseria; Protein Binding; Quinolones | 1992 |
Postantibiotic effect of CI-960, enoxacin and ciprofloxacin on Escherichia coli: effect on morphology and haemolysin activity.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Escherichia coli; Fluoroquinolones; Hemolysin Proteins; Microbial Sensitivity Tests; Quinolones; Trimethoprim, Sulfamethoxazole Drug Combination | 1992 |
Absence of bactericidal activity of sparfloxacin and ciprofloxacin under anaerobic conditions.
Topics: Anaerobiosis; Anti-Infective Agents; Ciprofloxacin; Clostridium; Fluoroquinolones; Pseudomonas; Quinolones | 1992 |
In vitro antistaphylococcal activities of two investigative fluoroquinolones, CI-960 and WIN 57273, compared with those of ciprofloxacin, mupirocin (pseudomonic acid), and peptide-class antimicrobial agents.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mupirocin; Quinolones; Staphylococcus | 1992 |
Susceptibilities of penicillin-susceptible and -resistant strains of Streptococcus pneumoniae to RP 59500, vancomycin, erythromycin, PD 131628, sparfloxacin, temafloxacin, win 57273, ofloxacin, and ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Erythromycin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Penicillin Resistance; Quinolones; Streptococcus pneumoniae; Vancomycin; Virginiamycin | 1992 |
Comparative activity of ciprofloxacin, ofloxacin, sparfloxacin, temafloxacin, CI-960, CI-990, and WIN 57273 against anaerobic bacteria.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones | 1992 |
Kinetic disposition of temafloxacin and ciprofloxacin in a murine model of pneumococcal pneumonia. Relevance for drug efficacy.
Topics: Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Female; Fluoroquinolones; Injections, Subcutaneous; Lung; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Pneumonia, Pneumococcal; Quinolones | 1992 |
In vitro evaluation of E-4695, a new fluoro-naphthyridine.
Topics: Anti-Bacterial Agents; Azetidines; Bacteria; Ciprofloxacin; Drug Evaluation, Preclinical; Enoxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones | 1992 |
Pefloxacin and ciprofloxacin in the treatment of uncomplicated gonococcal urethritis in males [corrected].
Topics: 4-Quinolones; Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Ciprofloxacin; Drug Administration Schedule; Drug Resistance, Microbial; Fluoroquinolones; Gonorrhea; Humans; Male; Middle Aged; Neisseria gonorrhoeae; Pefloxacin; Quinolones; Tetracycline Resistance; Urethritis | 1992 |
CI-960, a new fluoroquinolone, for therapy of experimental ciprofloxacin-susceptible and -resistant Staphylococcus aureus endocarditis.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Endocarditis, Bacterial; Fluoroquinolones; Kidney; Male; Methicillin Resistance; Microbial Sensitivity Tests; Quinolones; Rabbits; Spleen; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 1992 |
Pharmacokinetic studies of CP-74,667, a new quinolone, in laboratory animals.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Bile; Blood Proteins; Chromatography, High Pressure Liquid; Ciprofloxacin; Dogs; Female; Fluoroquinolones; Half-Life; Injections, Intravenous; Macaca fascicularis; Male; Mice; Protein Binding; Quinolones; Rabbits; Rats; Tissue Distribution | 1992 |
In vitro activity of CP-74667 compared with four other fluoroquinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Enoxacin; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones | 1992 |
In vitro and in vivo antibacterial activities of AM-1155, a new 6-fluoro-8-methoxy quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; DNA Topoisomerases, Type II; Drug Evaluation, Preclinical; Fluoroquinolones; Gatifloxacin; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Piperazines; Quinolones; Tissue Distribution | 1992 |
Comparative in vitro activities of a new quinolone, OPC-17116, possessing potent activity against gram-positive bacteria.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Topoisomerases, Type II; Fluoroquinolones; Gram-Positive Bacteria; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Piperazines; Quinolones; Staphylococcus aureus | 1992 |
In vitro activity of the new quinolone lomefloxacin against Mycobacterium tuberculosis.
Topics: Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones | 1992 |
In vivo efficacy of a new fluoroquinolone, sparfloxacin, against penicillin-susceptible and -resistant and multiresistant strains of Streptococcus pneumoniae in a mouse model of pneumonia.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; Female; Fluoroquinolones; Leukopenia; Lung; Mice; Mice, Inbred C57BL; Penicillin Resistance; Pneumonia, Pneumococcal; Quinolones; Species Specificity; Streptococcus pneumoniae | 1992 |
Susceptibility of Rickettsia conorii, R. rickettsii, and Coxiella burnetii to PD 127,391, PD 131,628, pefloxacin, ofloxacin, and ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Coxiella burnetii; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pefloxacin; Quinolones; Rickettsia; Rickettsia rickettsii; Viral Plaque Assay | 1992 |
The comparative activity of fleroxacin, three other quinolones and eight unrelated antimicrobial agents.
Topics: Anti-Bacterial Agents; Cephalosporins; Ciprofloxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1992 |
In vitro and in vivo evaluation of BMY 45243, a new 5-amino-naphthyridone derivative.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Female; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Naphthyridines; Quinolones; Solubility | 1992 |
Ciprofloxacin and dexamethasone inhibit the proliferation of human retinal pigment epithelial cells in culture.
Topics: Animals; Cell Division; Cells, Cultured; Ciprofloxacin; Dexamethasone; Electroretinography; Fundus Oculi; Humans; Lethal Dose 50; Pigment Epithelium of Eye; Quinolones; Rabbits | 1991 |
Characterization of high-level quinolone resistance in Campylobacter jejuni.
Topics: Anti-Infective Agents; Campylobacter jejuni; Ciprofloxacin; DNA Topoisomerases, Type II; DNA, Superhelical; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Norfloxacin; Quinolones; Topoisomerase II Inhibitors | 1991 |
[Intra-macrophagic activity of antibiotics combinations against Mycobacterium marinum].
Topics: Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Erythromycin; Ethambutol; Fluoroquinolones; Humans; In Vitro Techniques; Macrophages; Minocycline; Mycobacterium; Quinolones; Rifabutin; Rifamycins | 1991 |
Activity of new quinolones against ciprofloxacin-resistant staphylococci.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Staphylococcus | 1991 |
The in-vitro activity of temafloxacin compared with other antimicrobial agents.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Species Specificity | 1991 |
In-vitro activity of WIN 57273 compared to the activity of other fluoroquinolones and two beta-lactam antibiotics.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Ciprofloxacin; Fluoroquinolones; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones | 1991 |
Mechanistic studies of the phototoxic potential of PD 117596, a quinolone antibacterial compound.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Antioxidants; Ciprofloxacin; Dose-Response Relationship, Drug; Fluoroquinolones; Free Radical Scavengers; Hemolysis; Male; Mice; Mice, Inbred Strains; Nalidixic Acid; Nitroso Compounds; Oxygen; Photochemistry; Photolysis; Quinolones; Thiobarbiturates | 1991 |
Bactericidal activity of sparfloxacin and ciprofloxacin under anaerobic conditions.
Topics: Anaerobiosis; Anti-Infective Agents; Bacteroides fragilis; Ciprofloxacin; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones | 1991 |
Outer membrane changes in quinolone resistant Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Pseudomonas aeruginosa; Quinolones | 1991 |
Activity of temafloxacin and other fluoroquinolones against typical and atypical community-acquired respiratory tract pathogens.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Respiratory Tract Infections | 1991 |
In vitro activity of temafloxacin against gram-positive cocci including methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Ciprofloxacin; Enterococcus; Fluoroquinolones; Gram-Positive Cocci; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Staphylococcus aureus; Streptococcus | 1991 |
In vitro activity of temafloxacin against gram-negative bacteria: an overview.
Topics: Anti-Infective Agents; Campylobacter; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Respiratory Tract Infections; Sexually Transmitted Diseases, Bacterial | 1991 |
Assessment of temafloxacin neurotoxicity in rodents.
Topics: Animals; Anti-Infective Agents; Central Nervous System; Ciprofloxacin; Enoxacin; Fluoroquinolones; Male; Mice; Mice, Inbred ICR; Motor Activity; Oxolinic Acid; Phenylbutyrates; Quinolones; Rats; Rats, Inbred Strains; Seizures | 1991 |
Intramuscular and oral disposition of enrofloxacin in African grey parrots following single and multiple doses.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Biological Availability; Ciprofloxacin; Dose-Response Relationship, Drug; Enrofloxacin; Fluoroquinolones; Half-Life; Injections, Intramuscular; Parrots; Quinolones | 1991 |
Phenotypic characterization of quinolone-resistant mutants of Enterobacteriaceae selected from wild type, gyrA type and multiply-resistant (marA) type strains.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Enterobacter cloacae; Enterobacteriaceae; Escherichia coli; Fluoroquinolones; Klebsiella pneumoniae; Mutation; Nalidixic Acid; Phenotype; Quinolones; Serratia marcescens; Species Specificity | 1991 |
Anti-staphylococcal activity of temafloxacin, ciprofloxacin, ofloxacin and enoxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Oxacillin; Penicillin Resistance; Quinolones; Staphylococcal Infections; Staphylococcus | 1991 |
The in-vitro activity of tosufloxacin, a new fluorinated quinolone, compared with that of ciprofloxacin and temafloxacin.
Topics: Anti-Infective Agents; Bacteria; Bacteria, Aerobic; Bacteria, Anaerobic; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Quinolones | 1991 |
Pharmacokinetics of four fluoroquinolones in an animal model of infected lung.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; Fluoroquinolones; Lung Diseases; Mice; Mice, Inbred Strains; Ofloxacin; Pneumococcal Infections; Quinolones; Streptococcus pneumoniae | 1991 |
Comparative pharmacokinetic disposition of fluoroquinolones in the lung.
Topics: Administration, Oral; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Injections, Intravenous; Lung; Quinolones | 1991 |
In vitro activity of sparfloxacin and six reference antibiotics against gram-positive bacteria.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Positive Bacteria; Humans; Quinolones | 1991 |
Fluorometric and high-performance liquid chromatographic measurement of quinolone uptake by human neutrophils.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fleroxacin; Fluorescence; Fluoroquinolones; Humans; Neutrophils; Norfloxacin; Ofloxacin; Quinolones | 1991 |
Cross-resistance and cross-susceptibility between fluoroquinolone agents.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Predictive Value of Tests; Quinolones | 1991 |
Anti-Mycobacterium leprae activity of several quinolones studied in the mouse.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Leprosy; Mice; Mycobacterium leprae; Quinolones | 1991 |
Inhibitory effects of ciprofloxacin and sparfloxacin on DNA gyrase purified from fluoroquinolone-resistant strains of methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Topoisomerases, Type II; DNA, Superhelical; Drug Resistance, Microbial; Fluoroquinolones; Methicillin Resistance; Microbial Sensitivity Tests; Novobiocin; Quinolones; Staphylococcus aureus; Topoisomerase II Inhibitors | 1991 |
Mechanism of action of sparfloxacin against and mechanism of resistance in gram-negative and gram-positive bacteria.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Probes; DNA, Bacterial; Drug Resistance, Microbial; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Mutation; Phenotype; Pseudomonas aeruginosa; Quinolones | 1991 |
[In vitro bactericidal effect of temafloxacin and tosufloxacin against streptococci].
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enterococcus faecalis; Enterococcus faecium; Fluoroquinolones; In Vitro Techniques; Naphthyridines; Pefloxacin; Quinolones; Streptococcus; Streptococcus agalactiae; Streptococcus bovis; Streptococcus pneumoniae; Streptococcus pyogenes; Streptococcus sanguis | 1991 |
[In vitro effect of new fluoroquinolones and betalactamines combinations against enterococci].
Topics: Amoxicillin; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enterococcus faecalis; Fluoroquinolones; Imipenem; In Vitro Techniques; Naphthyridines; Piperacillin; Quinolones | 1991 |
Antibacterial activity of a new tetracyclic quinolone, No. 5290, against norfloxacin- and ciprofloxacin-resistant strains of Staphylococcus aureus.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Mutation; Norfloxacin; Piperazines; Quinolones; Staphylococcus aureus; Thiazoles | 1991 |
In vivo evaluation of NM441, a new thiazeto-quinoline derivative.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dogs; Drug Evaluation, Preclinical; Enoxacin; Female; Fluoroquinolones; Male; Mice; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Prodrugs; Quinolones; Respiratory Tract Infections; Streptococcal Infections; Urinary Tract Infections | 1991 |
Mechanism of quinolone mutagenicity in bacteria.
Topics: Anti-Infective Agents; Blotting, Southern; Ciprofloxacin; DNA Topoisomerases, Type II; Enrofloxacin; Escherichia coli; Fleroxacin; Fluoroquinolones; Genes, Bacterial; Mutation; Novobiocin; Ofloxacin; Oxolinic Acid; Quinolones; Salmonella | 1991 |
Antipneumococcal activity of ciprofloxacin, ofloxacin, and temafloxacin in an experimental mouse pneumonia model at various stages of the disease.
Topics: Amoxicillin; Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; Erythromycin; Female; Fluoroquinolones; Lung; Mice; Mice, Inbred C57BL; Ofloxacin; Pneumonia, Pneumococcal; Quinolones; Sepsis; Streptococcus pneumoniae | 1991 |
Activity of temafloxacin against respiratory pathogens.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Cells, Cultured; Ciprofloxacin; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Gerbillinae; Gram-Positive Bacteria; Guinea Pigs; Male; Mice; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Respiratory Tract Infections | 1991 |
In vitro and in vivo antibacterial activities of E-4497, a new 3-amine-3-methyl-azetidinyl tricyclic fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Interactions; Fluoroquinolones; Magnesium; Male; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones | 1991 |
In-vitro activity of sparfloxacin, a new quinolone antimicrobial agent.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Blood Proteins; Ciprofloxacin; Fluoroquinolones; Humans; Lactams; Microbial Sensitivity Tests; Protein Binding; Quinolones | 1990 |
Lomefloxacin-induced modification of the kinetics of growth of gram-negative bacteria and susceptibility to phagocytic killing by human neutrophils.
Topics: Anti-Infective Agents; Cell Division; Ciprofloxacin; Escherichia coli; Fluoroquinolones; Gram-Negative Bacteria; Humans; Neutrophils; Norfloxacin; Nucleic Acids; Phagocytosis; Pseudomonas aeruginosa; Quinolones; Tritium | 1990 |
MICs and MBCs of Win 57273 against Mycobacterium avium and M. tuberculosis.
Topics: Anti-Infective Agents; Ciprofloxacin; Culture Media; Fluoroquinolones; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Mycobacterium avium; Mycobacterium tuberculosis; Ofloxacin; Quinolones | 1990 |
Antibacterial activity of fluoroquinolones in combination with zidovudine.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enoxacin; Enterobacteriaceae; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Salmonella; Staphylococcus; Zidovudine | 1990 |
Cephalosporin 3'-quinolone esters with a dual mode of action.
Topics: Animals; Anti-Infective Agents; Cefotaxime; Cephalosporins; Chemical Phenomena; Chemistry; Ciprofloxacin; Enterobacter; Escherichia coli Infections; Fleroxacin; Fluoroquinolones; Hydrolysis; Mice; Molecular Structure; Pneumococcal Infections; Prodrugs; Quinolones; Rats; Staphylococcus aureus; Structure-Activity Relationship | 1990 |
Quinolone-induced differential modification of IL-1 alpha and IL-1 beta production by LPS-stimulated human monocytes.
Topics: Blotting, Northern; Ciprofloxacin; Humans; In Vitro Techniques; Interleukin-1; Lipopolysaccharides; Monocytes; Quinolones; RNA, Messenger; Time Factors | 1990 |
Possible interaction of fluoroquinolones with the benzodiazepine-GABAA-receptor complex.
Topics: Adult; Animals; Brain Chemistry; Ciprofloxacin; Double-Blind Method; Electroencephalography; Female; Flunitrazepam; Humans; In Vitro Techniques; Male; Middle Aged; Norfloxacin; Ofloxacin; Quinolones; Radioligand Assay; Random Allocation; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Membranes | 1990 |
Mechanism of action of lomefloxacin.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; DNA Topoisomerases, Type II; DNA, Bacterial; DNA, Superhelical; Fluoroquinolones; Kinetics; Microbial Sensitivity Tests; Norfloxacin; Quinolones; Rec A Recombinases | 1990 |
Quinolones in collagen shields to treat aminoglycoside-resistant pseudomonal keratitis.
Topics: Animals; Ciprofloxacin; Collagen; Colony Count, Microbial; Cornea; Drug Resistance, Microbial; Eye Infections, Bacterial; Keratitis; Norfloxacin; Pharmaceutical Vehicles; Pseudomonas aeruginosa; Quinolones; Rabbits; Tobramycin | 1990 |
Pharmacokinetic determination of relative potency of quinolone inhibition of caffeine disposition.
Topics: Caffeine; Ciprofloxacin; Drug Interactions; Enoxacin; Humans; Male; Models, Biological; Norfloxacin; Ofloxacin; Pipemidic Acid; Quinolones | 1990 |
In-vitro activity of PD 117 596, a new quinolone, against bacterial isolates from cancer patients.
Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Neoplasms; Quinolones | 1990 |
In vitro activities of 4-quinolones against the fish pathogen Aeromonas salmonicida.
Topics: Aeromonas; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enrofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Osmolar Concentration; Oxolinic Acid; Quinolones; Sodium Chloride | 1990 |
Determination of temafloxacin, sarafloxacin, and difloxacin in bulk drug and dosage forms by high-performance liquid chromatography.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Quinolones; Solubility; Spectrophotometry, Ultraviolet | 1990 |
In vitro susceptibility of selected veterinary bacterial pathogens to ciprofloxacin, enrofloxacin and norfloxacin.
Topics: Actinobacillus; Actinomyces; Anti-Infective Agents; Ciprofloxacin; Corynebacterium; Enrofloxacin; Erysipelothrix; Fluoroquinolones; Haemophilus; In Vitro Techniques; Microbial Sensitivity Tests; Norfloxacin; Pasteurella; Quinolones; Rhodococcus; Streptococcus | 1990 |
In vitro activities of tosufloxacin, temafloxacin, and A-56620 against pathogens of diarrhea.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ciprofloxacin; Diarrhea; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Quinolones | 1990 |
[Therapeutic drug monitoring of fluoroquinolone].
Topics: Anti-Infective Agents; Bile; Biological Assay; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones; Sputum | 1990 |
In vitro activities of irloxacin and E-3846, two new quinolones.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones | 1990 |
Susceptibility pattern of bacterial isolates to lomefloxacin.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Nalidixic Acid; Norfloxacin; Quinolones | 1990 |
Comparative in vitro activity of lomefloxacin, a new difluoroquinolone.
Topics: Anti-Infective Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Ceftazidime; Ciprofloxacin; Drug Evaluation, Preclinical; Fluoroquinolones; Gentamicins; Microbial Sensitivity Tests; Norfloxacin; Quinolones | 1989 |
Studies on the emergence of resistance to lomefloxacin in vitro.
Topics: Anti-Infective Agents; Ciprofloxacin; Cystitis; Drug Resistance, Microbial; Escherichia coli; Fluoroquinolones; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Biological; Norfloxacin; Quinolones | 1989 |
High-performance liquid chromatography for the determination of three new fluoroquinolones, fleroxacin, temafloxacin and A-64730, in biological fluids.
Topics: Anti-Infective Agents; Bile; Chromatography, High Pressure Liquid; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Humans; Molecular Structure; Naphthyridines; Quinolones; Spectrometry, Fluorescence | 1989 |
Comparative antimycobacterial activities of difloxacin, temafloxacin, enoxacin, pefloxacin, reference fluoroquinolones, and a new macrolide, clarithromycin.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Clarithromycin; Enoxacin; Erythromycin; Fluoroquinolones; Microbial Sensitivity Tests; Mycobacterium; Pefloxacin; Quinolones | 1989 |
Fluorinated 4-quinolones induce hyperproduction of interleukin 2.
Topics: Ciprofloxacin; Enzyme Activation; Flow Cytometry; Gene Expression Regulation; Humans; In Vitro Techniques; Interleukin-2; Lymphocytes; Phytohemagglutinins; Protein Kinase C; Quinolones; Receptors, Interleukin-2; Receptors, Transferrin; RNA, Messenger | 1989 |
Fluorometric assay for fleroxacin uptake by bacterial cells.
Topics: Ciprofloxacin; Escherichia coli; Fleroxacin; Quinolones; Spectrometry, Fluorescence | 1989 |
High-performance liquid chromatographic method for the simultaneous determination of enrofloxacin and its primary metabolite ciprofloxacin in canine serum and prostatic tissue.
Topics: Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Dogs; Enrofloxacin; Fluoroquinolones; Male; Prostate; Quinolones; Spectrophotometry, Ultraviolet | 1989 |
In vitro and in vivo antibacterial activities of KB-5246, a new tetracyclic quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Male; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Phenalenes; Quinolones | 1989 |
In vitro activities of T-3262, NY-198, fleroxacin (AM-833; RO 23-6240), and other new quinolone agents against clinically isolated Chlamydia trachomatis strains.
Topics: Anti-Infective Agents; Chlamydia; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Naphthyridines; Quinolones | 1988 |
Quinolones, theophylline, and diclofenac interactions with the gamma-aminobutyric acid receptor.
Topics: Animals; Ciprofloxacin; Diclofenac; Drug Synergism; GABA Antagonists; In Vitro Techniques; Male; Muscimol; Nalidixic Acid; Ofloxacin; Quinolones; Rats; Rats, Inbred Strains; Receptors, GABA-A; Theophylline | 1988 |
Synergy studies of ciprofloxacin and other quinolone derivatives in combination with further antibiotics.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Synergism; Enterobacter; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Quinolones; Streptococcus | 1987 |
In vitro activities of ciprofloxacin, ofloxacin, norfloxacin and rosoxacin compared with cinoxacin and trimethoprim.
Topics: 4-Quinolones; Acinetobacter; Anti-Infective Agents; Anti-Infective Agents, Urinary; Cinoxacin; Ciprofloxacin; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines; Quinolones; Trimethoprim | 1985 |
The comparative in vitro activity of twelve 4-quinolone antimicrobials against enteric pathogens.
Topics: 4-Quinolones; Aeromonas; Anti-Bacterial Agents; Anti-Infective Agents; Campylobacter fetus; Cinoxacin; Ciprofloxacin; Diarrhea; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Intestines; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Salmonella; Shigella; Vibrio cholerae; Vibrio parahaemolyticus; Yersinia enterocolitica | 1985 |
The comparative activity of twelve 4-quinolone antimicrobials against Haemophilus influenzae and Streptococcus pneumoniae.
Topics: 4-Quinolones; Anti-Infective Agents; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Streptococcus pneumoniae | 1985 |
Comparative in vitro studies with 4-quinolone antimicrobials.
Topics: 4-Quinolones; Anti-Infective Agents; Bacteria; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones | 1985 |
In vitro activity of temafloxacin, a new difluoro quinolone antimicrobial agent.
Topics: Anti-Bacterial Agents; Cefotaxime; Chemical Phenomena; Chemistry; Ciprofloxacin; Culture Media; Drug Resistance, Microbial; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Hydrogen-Ion Concentration; Imipenem; Magnesium; Ofloxacin; Oxazines; Pseudomonas; Quinolines; Quinolones; Thienamycins | 1988 |
In vitro activity of lomefloxacin, a new quinolone antimicrobial agent, in comparison with those of other agents.
Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria; Blood Proteins; Cefuroxime; Ciprofloxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Ofloxacin; Oxazines; Protein Binding; Pseudomonas aeruginosa; Quinolines; Quinolones; Staphylococcus; Streptococcus; Trimethoprim | 1988 |
Activity of E-3846, a new fluoroquinolone, in vitro and in experimental cystitis and pyelonephritis in rats.
Topics: Animals; Anti-Infective Agents; Anti-Infective Agents, Urinary; Bacteria; Chemical Phenomena; Chemistry; Ciprofloxacin; Cystitis; Disease Models, Animal; Enterobacteriaceae; Escherichia coli Infections; Female; Fluoroquinolones; Hydrogen-Ion Concentration; Klebsiella Infections; Norfloxacin; Proteus Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Pyelonephritis; Quinolines; Quinolones; Rats; Rats, Inbred Strains; Staphylococcus; Streptococcal Infections; Streptococcus | 1988 |
[In vitro activity of new quinolones against Mycoplasma pathogenic to humans].
Topics: 4-Quinolones; Anti-Bacterial Agents; Ciprofloxacin; Enoxacin; Humans; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma pneumoniae; Mycoplasmataceae; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Quinolones; Ureaplasma | 1988 |
Comparative in vitro activity of the new difluoro-quinolone temafloxacin (A-62254) against bacterial isolates from cancer patients.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Neoplasms; Quinolones; Staphylococcus; Streptococcus | 1988 |
Correlation of in vitro activities of the fluoroquinolones to their in vivo efficacies.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1988 |
In vitro activities of ofloxacin and four other new quinoline-carboxylic acids against Chlamydia trachomatis.
Topics: Anti-Infective Agents; Chlamydia trachomatis; Ciprofloxacin; Doxycycline; Fleroxacin; Fluoroquinolones; Minocycline; Norfloxacin; Ofloxacin; Quinolones | 1988 |
Sensitivity of urinary staphylococci to ciprofloxacin and acrosoxacin.
Topics: 4-Quinolones; Anti-Infective Agents; Ciprofloxacin; Humans; Microbial Sensitivity Tests; Quinolines; Quinolones; Staphylococcus; Urinary Tract Infections | 1985 |
Inhibition of conjugal transfer by new quinolinic compounds.
Topics: 4-Quinolones; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Conjugation, Genetic; Escherichia coli; Nalidixic Acid; Norfloxacin; Quinolines; Quinolones | 1985 |
In vitro activity of lomefloxacin (SC-47111; NY-198), a difluoroquinolone 3-carboxylic acid, compared with those of other quinolones.
Topics: Anaerobiosis; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Magnesium; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Quinolones | 1988 |
Efficacy of NY-198 against experimental Legionnaires disease.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Guinea Pigs; Legionnaires' Disease; Male; Quinolones; Tissue Distribution | 1988 |
Therapeutic efficacy of ofloxacin, ciprofloxacin and NY-198 in experimentally infected normal and alloxan-induced diabetic mice.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Diabetes Mellitus, Experimental; Female; Fluoroquinolones; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Ofloxacin; Pyelonephritis; Quinolones; Respiratory Tract Infections; Urinary Tract Infections | 1988 |
In-vitro assessment of lomefloxacin (SC-47111)--a new quinolone derivative.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones | 1988 |
Effects of quinolones on mitogen-stimulated human mononuclear leucocytes.
Topics: 4-Quinolones; Adult; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; In Vitro Techniques; Lymphocyte Activation; Norfloxacin; Phytohemagglutinins; Quinolines; Quinolones | 1988 |
Comparative antibacterial activities of temafloxacin hydrochloride (A-62254) and two reference fluoroquinolones.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Female; Fluoroquinolones; Hydrogen-Ion Concentration; Mice; Microbial Sensitivity Tests; Pyelonephritis; Quinolines; Quinolones | 1987 |
In vitro activity of E-3846, a new fluoroquinolone, against gram-negative and gram-positive bacteria.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Norfloxacin; Quinolones | 1987 |
Comparative activity of three new fluoroquinolones.
Topics: Anti-Infective Agents; Bacillus; Bacteria; Ciprofloxacin; Corynebacterium; Enterobacteriaceae; Fluoroquinolones; Microbial Sensitivity Tests; Pseudomonas; Quinolones; Staphylococcus; Streptococcus | 1987 |
Frequency and expression of mutational resistance to the 4-quinolone antibacterials.
Topics: 4-Quinolones; Anti-Bacterial Agents; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Escherichia coli; Fluoroquinolones; Mutation; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pipemidic Acid; Quinolines; Quinolizines; Quinolones | 1986 |
The activity of ciprofloxacin and other 4-quinolones against Chlamydia trachomatis and Mycoplasmas in vitro.
Topics: 4-Quinolones; Anti-Bacterial Agents; Chlamydia trachomatis; Ciprofloxacin; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Mycoplasma; Nalidixic Acid; Norfloxacin; Oxolinic Acid; Oxytetracycline; Quinolines; Quinolones; Ureaplasma | 1984 |
In vitro activities of the spectinomycin analog U-63366 and four quinolone derivatives against Neisseria gonorrhoeae.
Topics: 4-Quinolones; Anti-Bacterial Agents; Ciprofloxacin; Microbial Sensitivity Tests; Nalidixic Acid; Neisseria gonorrhoeae; Norfloxacin; Quinolines; Quinolones; Spectinomycin | 1984 |
Distribution of ciprofloxacin in the dog prostate and various tissues.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Body Fluids; Ciprofloxacin; Dogs; Hydrogen-Ion Concentration; Infusions, Parenteral; Male; Nalidixic Acid; Norfloxacin; Prostate; Quinolines; Quinolones; Tissue Distribution | 1984 |
Comparison of sparfloxacin, temafloxacin, and ciprofloxacin for prophylaxis and treatment of experimental foreign-body infection by methicillin-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Foreign Bodies; Guinea Pigs; Methicillin Resistance; Microbial Sensitivity Tests; Quinolones; Rats; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 1995 |
Activities of three investigational fluoroquinolones (BAY y 3118, DU-6859a, and clinafloxacin) against Neisseria gonorrhoeae isolates with diminished susceptibilities to ciprofloxacin and ofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Quinolones; Spiro Compounds | 1995 |
Interactions between fluoroquinolones, Mg2+, DNA and DNA gyrase, studied by phase partitioning in an aqueous two-phase system and by affinity chromatography.
Topics: Animals; Anti-Infective Agents; Bacteria; Cattle; Chemical Phenomena; Chemistry, Physical; Chromatography, Affinity; Ciprofloxacin; Dextrans; DNA; DNA Topoisomerases, Type II; DNA, Bacterial; Escherichia coli; Fluoroquinolones; Magnesium; Polyethylene Glycols; Quinolones; Topoisomerase II Inhibitors; Water | 1994 |
Modifications for disk diffusion susceptibility testing criteria of clinafloxacin (CI-960, AM-1091, PD127371) and fleroxacin (Ro 23-6240, AM-833) following studies with a challenge panel of ciprofloxacin-resistant clinical isolates.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones; Sensitivity and Specificity | 1995 |
A novel gyrB mutation in a fluoroquinolone-resistant clinical isolate of Salmonella typhimurium.
Topics: Anti-Infective Agents; Base Sequence; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Nalidixic Acid; Quinolones; Salmonella typhimurium | 1995 |
Comparative in-vitro activities of the new quinolone, Bay y 3118, and ciprofloxacin, sparfloxacin, tosufloxacin, CI-960 and CI-990.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Quinolones | 1993 |
Comparative single-dose pharmacokinetics of four quinolones, oxolinic acid, flumequine, sarafloxacin, and enrofloxacin, in Atlantic salmon (Salmo salar) held in seawater at 10 degrees C.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Biological Availability; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Injections, Intravenous; Oxolinic Acid; Quinolizines; Quinolones; Salmon; Seawater; Temperature | 1995 |
[The efficacy of the clinical use of the preparation Cifran in treating surgical infection].
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Drug Evaluation; Female; Fluoroquinolones; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Infusions, Intravenous; Intraoperative Care; Male; Middle Aged; Postoperative Care; Quinolones; Surgical Wound Infection; Tablets; Time Factors | 1994 |
Intestinal elimination of sparfloxacin, fleroxacin, and ciprofloxacin in rats.
Topics: Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Ileum; Jejunum; Male; Quinolones; Rats; Rats, Sprague-Dawley | 1995 |
Suggested modifications for disk diffusion susceptibility testing criteria for levofloxacin and sparfloxacin following tests with a predictor panel of ciprofloxacin-resistant clinical isolates.
Topics: Ciprofloxacin; Diffusion; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Reproducibility of Results | 1995 |
In-vitro postantibiotic effect of sparfloxacin and ciprofloxacin against Pseudomonas aeruginosa and Enterococcus faecalis.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enterococcus faecalis; Fluoroquinolones; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Quinolones; Time Factors | 1994 |
Epicondylitis after treatment with fluoroquinolone antibiotics.
Topics: 4-Quinolones; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Male; Middle Aged; Orchitis; Pefloxacin; Quinolones; Respiratory Tract Infections; Tennis Elbow | 1995 |
Effect of aerobic and anaerobic environments on antistaphylococcal activities of five fluoroquinolones.
Topics: Anaerobiosis; Anti-Infective Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Ciprofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Staphylococcus aureus | 1995 |
Comparative in-vitro activity of Bay y 3118, a new quinolone, and ciprofloxacin against Mycobacterium tuberculosis and Mycobacterium avium complex.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Mycobacterium tuberculosis; Quinolones; Sputum; Tuberculosis, Pulmonary | 1995 |
[Bactericidal activity of ciprofloxacin and sparfloxacin. Comparison with others active antibiotics against Pasteurella multocida].
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Cefpodoxime; Ceftizoxime; Ciprofloxacin; Dose-Response Relationship, Drug; Fluoroquinolones; In Vitro Techniques; Pasteurella multocida; Quinolones | 1995 |
Susceptibility of ciprofloxacin-resistant staphylococci and enterococci to clinafloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enterococcus faecalis; Fluoroquinolones; Methicillin Resistance; Microbial Sensitivity Tests; Quinolones; Staphylococcus aureus | 1995 |
Multicenter in vitro comparative study of fluoroquinolones against 25,129 gram-positive and gram-negative clinical isolates.
Topics: Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1995 |
In vitro antimicrobial susceptibility of glycopeptide-resistant enterococci.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Depsipeptides; Drug Resistance, Microbial; Enterococcus; Fluoroquinolones; Fusidic Acid; Microbial Sensitivity Tests; Minocycline; Naphthyridines; Novobiocin; Peptides, Cyclic; Quinolones; Teicoplanin; Vancomycin; Virginiamycin | 1995 |
Cross-resistance analysis for DU-6859a, a new fluoroquinolone, compared to six structurally similar compounds (ciprofloxacin, clinafloxacin, fleroxacin, levofloxacin, ofloxacin, and sparfloxacin).
Topics: Anti-Infective Agents; Bacteria, Aerobic; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Fleroxacin; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Spiro Compounds | 1995 |
[Pharmacokinetics of baytril (enrofloxacin) in dogs].
Topics: Administration, Oral; Animals; Anti-Infective Agents; Biological Availability; Ciprofloxacin; Dogs; Enrofloxacin; Female; Fluoroquinolones; Injections, Intravenous; Male; Quinolones | 1994 |
Placental transfer of enrofloxacin and ciprofloxacin in rabbits.
Topics: Animals; Anti-Infective Agents; Blood Proteins; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Maternal-Fetal Exchange; Perfusion; Placenta; Pregnancy; Quinolones; Rabbits; Time Factors | 1994 |
Study of comparative antipneumococcal activities of penicillin G, RP 59500, erythromycin, sparfloxacin, ciprofloxacin, and vancomycin by using time-kill methodology.
Topics: Anti-Infective Agents; Ciprofloxacin; Erythromycin; Fluoroquinolones; Kinetics; Microbial Sensitivity Tests; Penicillin G; Quinolones; Streptococcus pneumoniae; Time Factors; Vancomycin; Virginiamycin | 1994 |
Dissociated resistance among fluoroquinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Mutation; Ofloxacin; Piperazines; Quinolones | 1994 |
In-vitro activity of new sulphanilil fluoroquinolones against Staphylococcus aureus.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Methicillin Resistance; Microbial Sensitivity Tests; Norfloxacin; Quinolones; Staphylococcal Infections; Staphylococcus aureus; Time Factors | 1994 |
Simultaneous determination of enrofloxacin and its primary metabolite ciprofloxacin in bovine milk and plasma by ion-pairing liquid chromatography.
Topics: Animals; Anti-Infective Agents; Biotransformation; Cattle; Chromatography, Ion Exchange; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Injections, Intravenous; Milk; Quinolones; Spectrophotometry, Ultraviolet; Ultrafiltration | 1994 |
Effect of newer quinolones on the extra- and intra-cellular chemiluminescence response of human polymorphonuclear leucocytes.
Topics: Anti-Infective Agents; Ciprofloxacin; Extracellular Space; Fluoroquinolones; Humans; Luminescent Measurements; Neutrophils; Ofloxacin; Quinolones; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
In-vitro activity of OPC-17116 against bacterial enteric pathogens.
Topics: Anti-Infective Agents; Ciprofloxacin; Enterobacteriaceae; Escherichia coli; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Piperazines; Quinolones; Tetracycline; Trimethoprim | 1994 |
The use of ciprofloxacin in veterinary proprietary products of enrofloxacin.
Topics: Anti-Infective Agents; Chromatography, Thin Layer; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Quinolones; Reference Standards; Spectrophotometry, Ultraviolet; Veterinary Medicine | 1994 |
In vitro activities of enoxacin, enrofloxacin, sparfloxacin, and ciprofloxacin against Escherichia coli strains isolated from diarrheic lambs and kids.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Diarrhea; Diarrhea, Infantile; Enoxacin; Enrofloxacin; Escherichia coli; Fluoroquinolones; Humans; Infant, Newborn; Microbial Sensitivity Tests; Quinolones; Sheep; Sheep Diseases | 1994 |
Activity of CP 99,219 compared with those of ciprofloxacin, grepafloxacin, metronidazole, cefoxitin, piperacillin, and piperacillin-tazobactam against 489 anaerobes.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Cefoxitin; Ciprofloxacin; Fluoroquinolones; Metronidazole; Microbial Sensitivity Tests; Naphthyridines; Penicillanic Acid; Piperacillin; Piperazines; Quinolones; Tazobactam | 1994 |
In vitro activity of subinhibitory concentrations of quinolones on urea-splitting bacteria: effect on urease activity and on cell surface hydrophobicity.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enterobacteriaceae; Fluoroquinolones; Norfloxacin; Ofloxacin; Proteus; Providencia; Quinolones; Surface Properties; Urea; Urease | 1995 |
[Effectiveness of new quinolones in experimental aerogenic plague infection of albino mice].
Topics: 4-Quinolones; Administration, Inhalation; Animals; Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Lethal Dose 50; Mice; Nalidixic Acid; Pefloxacin; Plague; Quinolones | 1994 |
[Comparative evaluation of the effectiveness of fluoroquinolones in experimental anthrax infection].
Topics: Animals; Anthrax; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; Drug Evaluation, Preclinical; Evaluation Studies as Topic; Fluoroquinolones; Lethal Dose 50; Mice; Microbial Sensitivity Tests; Pefloxacin; Quinolones | 1994 |
In vitro activity of CP-99,219, a novel 7-(3-azabicyclo[3.1.0]hexyl) naphthyridone antimicrobial.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Topoisomerases, Type II; DNA, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Quinolones | 1994 |
Assessment of the bactericidal activity of sparfloxacin, ofloxacin, levofloxacin, and other fluoroquinolones compared with selected agents of proven efficacy against Listeria monocytogenes.
Topics: Ampicillin; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Levofloxacin; Listeria monocytogenes; Listeriosis; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Trimethoprim, Sulfamethoxazole Drug Combination | 1994 |
DU-6859a, a new fluoroquinolone agent. Comparative in vitro activity against enteric pathogens and multiresistant outpatient Escherichia coli.
Topics: Anti-Infective Agents; Ciprofloxacin; Diarrhea; Drug Resistance, Multiple; Escherichia coli; Fluoroquinolones; Gram-Negative Bacteria; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Quinolones; Spiro Compounds | 1994 |
In vitro activity of the new fluoroquinolone CP-99,219.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Quinolones | 1994 |
In vitro phototoxic activities of new quinolone antibacterial agents: lipid peroxidative potentials.
Topics: Absorption; Anti-Infective Agents; Azides; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Lipid Peroxidation; Norfloxacin; Ofloxacin; Oxygen; Photochemistry; Photosensitivity Disorders; Quinolones; Sodium Azide; Squalene; Ultraviolet Rays | 1994 |
Quinolone resistance in veterinary isolates of Salmonella.
Topics: Animals; Anti-Infective Agents; Chickens; Ciprofloxacin; Conjugation, Genetic; DNA, Bacterial; Drug Resistance, Microbial; Enrofloxacin; Fluoroquinolones; Lipopolysaccharides; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Poultry Diseases; Quinolones; Salmonella; Salmonella Infections, Animal; Turkeys | 1994 |
In-vitro activity of four new fluoroquinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quinolones | 1994 |
Risk factors for acquisition of urinary tract infections caused by ciprofloxacin resistant Escherichia coli.
Topics: Age Factors; Aged; Ciprofloxacin; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Infections; Humans; Quinolones; Retrospective Studies; Risk Factors; Urinary Catheterization; Urinary Tract Infections; Urologic Diseases | 1995 |
Increased activity of a new chlorofluoroquinolone, BAY y 3118, compared with activities of ciprofloxacin, sparfloxacin, and other antimicrobial agents against anaerobic bacteria.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones | 1994 |
Limited effects of temafloxacin compared with ciprofloxacin on T-lymphocyte function.
Topics: Anti-Infective Agents; Autoradiography; Blotting, Northern; Cells, Cultured; Ciprofloxacin; Fluoroquinolones; Gene Expression; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-2; Phytohemagglutinins; Quinolones; RNA, Messenger; T-Lymphocytes; Thymidine | 1994 |
In-vitro slime production by Staphylococcus epidermidis in presence of subinhibitory concentrations of ciprofloxacin, ofloxacin and sparfloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Staphylococcus epidermidis | 1994 |
The effect of temperature and pH on the solubility of quinolone compounds: estimation of heat of fusion.
Topics: Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Ciprofloxacin; Hot Temperature; Hydrogen-Ion Concentration; Norfloxacin; Quinolones; Solubility; Temperature; Thermodynamics | 1994 |
Treatment of mycoplasma contamination in a large panel of cell cultures.
Topics: Cells, Cultured; Ciprofloxacin; Diterpenes; Drug Resistance, Microbial; Minocycline; Mycoplasma; Quinolones | 1994 |
Ciprofloxacin and sparfloxacin penetration into human brain tissue and their activity as antagonists of GABAA receptor of rat vagus nerve.
Topics: Animals; Anti-Infective Agents; Brain; Ciprofloxacin; Dose-Response Relationship, Drug; Fluoroquinolones; GABA-A Receptor Antagonists; Male; Phenylacetates; Quinolones; Rats; Rats, Sprague-Dawley; Vagus Nerve | 1994 |
Comparative in vitro activities of new quinolones against coryneform bacteria.
Topics: Anti-Infective Agents; Ciprofloxacin; Corynebacterium; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1994 |
Comparative activities of eight quinolones against members of the Bacteroides fragilis group.
Topics: Anti-Infective Agents; Bacteroides fragilis; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1994 |
Only some anticonvulsants protect against seizures induced by aminophylline in quinolone-treated genetically epilepsy prone rats.
Topics: Aminophylline; Animals; Anticonvulsants; Cinoxacin; Ciprofloxacin; Electroencephalography; Female; Male; Quinolones; Rats; Rats, Sprague-Dawley; Seizures | 1993 |
Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after intravenous and oral administration of enrofloxacin in dogs.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Dogs; Enrofloxacin; Female; Fluoroquinolones; Injections, Intravenous; Male; Microbial Sensitivity Tests; Quinolones | 1993 |
In-vitro comparison of DU-6859a, a novel fluoroquinolone, with other quinolones and oral cephalosporins tested against 5086 recent clinical isolates.
Topics: Anti-Infective Agents; Bacteria, Aerobic; Cefixime; Cefotaxime; Cefuroxime; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1993 |
Susceptibilities of 123 Xanthomonas maltophilia strains to clinafloxacin, PD 131628, PD 138312, PD 140248, ciprofloxacin, and ofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Xanthomonas | 1994 |
In vivo effects of rufloxacin and ciprofloxacin on T-cell subsets and tumor necrosis factor production in mice infected with Bacteroides fragilis.
Topics: Animals; Anti-Infective Agents; Bacteroides fragilis; Bacteroides Infections; CD4-CD8 Ratio; Cell Division; Ciprofloxacin; Female; Fluoroquinolones; Mice; Mice, Inbred C3H; Organ Size; Quinolones; Spleen; T-Lymphocyte Subsets; T-Lymphocytes; Tumor Necrosis Factor-alpha | 1993 |
Correlation between umuC induction and Salmonella mutagenicity assay for quinolone antimicrobial agents.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; DNA-Directed DNA Polymerase; Enoxacin; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Gene Expression Regulation, Bacterial; Mutagenicity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Quinolones; Salmonella typhimurium; SOS Response, Genetics; Species Specificity | 1993 |
[Compared antibacterial activity of a new fluoroquinolone, sparfloxacin (AT 4140, RP 64206) and four other fluoroquinolones against 332 strains of enteropathogen bacteria].
Topics: Anti-Infective Agents; Campylobacter jejuni; Ciprofloxacin; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Helicobacter pylori; Humans; In Vitro Techniques; Ofloxacin; Pefloxacin; Quinolones; Salmonella; Shigella; Vibrio cholerae; Yersinia enterocolitica | 1993 |
In vitro and in vivo activities of Q-35, a new fluoroquinolone, against Mycoplasma pneumoniae.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Ciprofloxacin; Cricetinae; Drug Resistance, Microbial; Erythromycin; Female; Fluoroquinolones; Humans; Lung; Mesocricetus; Microbial Sensitivity Tests; Mycoplasma pneumoniae; Ofloxacin; Pneumonia, Mycoplasma; Quinolones | 1993 |
Antibacterial activities of OPC-17116, ofloxacin, and ciprofloxacin against 200 isolates of Neisseria gonorrhoeae.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Penicillin Resistance; Piperazines; Quinolones; Tetracycline Resistance | 1993 |
Evaluation of activity of temafloxacin against Bacteroides fragilis by an in vitro pharmacodynamic system.
Topics: Anaerobiosis; Anti-Infective Agents; Bacteroides fragilis; Cefotetan; Ciprofloxacin; Colony Count, Microbial; Culture Media; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones | 1993 |
In vitro activity of sparfloxacin compared with ciprofloxacin and ofloxacin against respiratory tract pathogens.
Topics: Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Respiratory Tract Infections | 1993 |
Induction of resistance of Streptococcus pneumoniae to quinolones in vitro.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones; Streptococcus pneumoniae | 1993 |
The in-vitro activity of Bay y 3118, a new chlorofluoroquinolone.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Chlamydia; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Lactams; Microbial Sensitivity Tests; Quinolones; Species Specificity; Staphylococcus | 1993 |
A multicenter study on the comparative in vitro activity of fleroxacin and three other quinolones: an interim report from 27 centers.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1993 |
Effects of new quinolones on Mycoplasma pneumoniae-infected hamsters.
Topics: Animals; Anti-Infective Agents; Antibodies, Bacterial; Ciprofloxacin; Cricetinae; Female; Fluoroquinolones; Half-Life; Humans; Lung; Mesocricetus; Mycoplasma pneumoniae; Ofloxacin; Pneumonia, Mycoplasma; Quinolones | 1993 |
Comparison of an HPLC and bioassay method to determine antimicrobial concentrations after intravenous and oral administration of enrofloxacin in four dogs.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Biological Assay; Chromatography, High Pressure Liquid; Ciprofloxacin; Dogs; Enrofloxacin; Fluoroquinolones; Injections, Intravenous; Quinolones; Serum Bactericidal Test | 1993 |
Antibacterial activity of NM394, the active form of prodrug NM441, a new quinolone.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Dioxolanes; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Naphthyridines; Ofloxacin; Piperazines; Quinolones; Topoisomerase II Inhibitors | 1993 |
In vitro and in vivo antibacterial activities of E-4868, a new fluoroquinolone with a 7-azetidin ring substituent.
Topics: Animals; Anti-Infective Agents; Bacteria; Ciprofloxacin; Culture Media; Fleroxacin; Fluoroquinolones; Horses; Male; Mice; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1993 |
Changes in adherence of respiratory pathogens to HEp-2 cells induced by subinhibitory concentrations of sparfloxacin, ciprofloxacin, and trimethoprim.
Topics: Anti-Infective Agents; Bacteria; Bacterial Adhesion; Carcinoma; Ciprofloxacin; Fluoroquinolones; Humans; Laryngeal Neoplasms; Quinolones; Respiratory Tract Infections; Trimethoprim; Tumor Cells, Cultured | 1993 |
The in-vitro activity of OPC-17116, a new 5-methyl substituted quinolone.
Topics: Amoxicillin; Anti-Infective Agents; Bacteroides fragilis; Cefaclor; Chlamydia trachomatis; Chlamydophila pneumoniae; Ciprofloxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Norfloxacin; Piperazines; Protein Binding; Quinolones; Staphylococcus | 1993 |
Incomplete cross-resistance between ciprofloxacin and sparfloxacin in staphylococci, with a note on selection pressure due to clinical use of ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Methicillin Resistance; Microbial Sensitivity Tests; Phenotype; Quinolones; Staphylococcus aureus | 1993 |
In-vitro activity of ciprofloxacin, temafloxacin, azithromycin, clarithromycin and metronidazole against Giardia lamblia.
Topics: Animals; Anti-Infective Agents; Azithromycin; Ciprofloxacin; Clarithromycin; Erythromycin; Fluoroquinolones; Giardia lamblia; Metronidazole; Microbial Sensitivity Tests; Quinolones | 1993 |
Effects of ciprofloxacin and enrofloxacin on zoxazolamine kinetics, plasma concentration and sleeping times in mice.
Topics: Animals; Anti-Infective Agents; Biotransformation; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Interactions; Enrofloxacin; Fluoroquinolones; Half-Life; Injections, Intraperitoneal; Male; Mice; Quinolones; Reflex, Abnormal; Sleep; Zoxazolamine | 1993 |
In vitro activity of sparfloxacin, ciprofloxacin, ofloxacin, and other antibiotics against bloodstream isolates of gram-positive cocci.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1993 |
Developmental toxicity of fleroxacin and comparative pharmacokinetics of four fluoroquinolones in the cynomolgus macaque (Macaca fascicularis).
Topics: Administration, Oral; Animals; Anti-Infective Agents; Ciprofloxacin; Embryo, Mammalian; Female; Fleroxacin; Fluoroquinolones; Macaca fascicularis; Norfloxacin; Pregnancy; Pregnancy, Animal; Quinolones | 1993 |
Topoisomerase IV is a target of quinolones in Escherichia coli.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Replication; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA, Bacterial; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; Mutation; Norfloxacin; Nucleic Acid Conformation; Quinolones | 1995 |
In vitro activity of E-4868, a new fluoroquinolone with a 7-azetidin ring, compared with ciprofloxacin, ofloxacin and fleroxacin.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Ciprofloxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1995 |
Difloxacin reverses multidrug resistance in HL-60/AR cells that overexpress the multidrug resistance-related protein (MRP) gene.
Topics: Anti-Infective Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Ciprofloxacin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoroquinolones; Gene Expression; HL-60 Cells; Humans; Microscopy, Confocal; Quinolones; Vincristine | 1995 |
Activities of ciprofloxacin and sparfloxacin against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones; Streptococcus pneumoniae | 1995 |
In vitro susceptibility to ciprofloxacin of bacterial strains isolated from chronic otitis media and chronic sinusitis.
Topics: Adult; Anti-Infective Agents; Bacteria; Chronic Disease; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Otitis Media; Quinolones; Sinusitis | 1995 |
Comparative in vitro activity of BAY Y 3118 with other fluoroquinolones.
Topics: Aminoglycosides; Ampicillin Resistance; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ciprofloxacin; Cross Infection; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1995 |
In vitro activity of MF 5137, a new potent 6-aminoquinolone.
Topics: 4-Quinolones; Anti-Infective Agents; Bacteria; Ciprofloxacin; Culture Media; Fluoroquinolones; Isoquinolines; Microbial Sensitivity Tests; Quinolones | 1995 |
Quinolone-induced arthropathy in the neonatal mouse. Morphological analysis of articular lesions produced by pipemidic acid and ciprofloxacin.
Topics: Animals; Animals, Newborn; Anti-Infective Agents; Body Weight; Cartilage, Articular; Ciprofloxacin; Female; Foot; Joint Diseases; Mice; Pipemidic Acid; Pregnancy; Quinolones | 1995 |
Proposed criteria for interpretation of susceptibilities of strains of Neisseria gonorrhoeae to ciprofloxacin, ofloxacin, enoxacin, lomefloxacin, and norfloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Diffusion; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Quinolones | 1995 |
Pharmacokinetics of enrofloxacin after single intravenous, intramuscular and subcutaneous injections in lactating cows.
Topics: Animals; Anti-Infective Agents; Cattle; Chromatography, High Pressure Liquid; Ciprofloxacin; Computer Simulation; Enrofloxacin; Escherichia coli; Female; Fluoroquinolones; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Lactation; Microbial Sensitivity Tests; Milk; Protein Binding; Quinolones | 1995 |
In vitro antibacterial activity of FA103, a new quinolone derivative of C-7 position with 7-perhydrodiazepinone.
Topics: Anti-Infective Agents; Azepines; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Norfloxacin; Ofloxacin; Quinolones | 1995 |
DNA gyrase and topoisomerase IV on the bacterial chromosome: quinolone-induced DNA cleavage.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA, Bacterial; DNA, Superhelical; Escherichia coli; Models, Biological; Mutation; Oxolinic Acid; Quinolones | 1996 |
Activity of CP 99,219 (trovafloxacin) compared with ciprofloxacin, sparfloxacin, clinafloxacin, lomefloxacin and cefuroxime against ten penicillin-susceptible and penicillin-resistant pneumococci by time-kill methodology.
Topics: Anti-Infective Agents; Cefuroxime; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Penicillin Resistance; Quinolones; Streptococcus pneumoniae | 1996 |
In vitro induction of micronuclei and chromosome aberrations by quinolones: possible mechanisms.
Topics: Animals; Anti-Infective Agents; Cell Cycle; Cell Survival; Cells, Cultured; Chromosome Aberrations; Ciprofloxacin; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Fibroblasts; Fluoroquinolones; Kinetochores; Lung; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenicity Tests; Mutagens; Quinolones | 1996 |
Penetration of enrofloxacin and ciprofloxacin into breast milk, and pharmacokinetics of the drugs in lactating rabbits and neonatal offspring.
Topics: Animals; Animals, Newborn; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Kinetics; Lactation; Metabolic Clearance Rate; Milk; Models, Biological; Pregnancy; Quinolones; Rabbits; Sensitivity and Specificity; Ultrafiltration | 1996 |
In vitro and in vivo antibacterial activities of CS-940, a new 6-fluoro-8-difluoromethoxy quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Drug Evaluation, Preclinical; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Male; Mice; Naphthyridines; Piperazines; Pneumonia, Bacterial; Quinolones | 1996 |
Detection of quinolone-resistant Neisseria gonorrhoeae.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Female; Fleroxacin; Fluoroquinolones; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Quinolones; Reference Standards | 1996 |
Mutations responsible for reduced susceptibility to 4-quinolones in clinical isolates of multi-resistant Salmonella typhi in India.
Topics: Amino Acid Sequence; Base Sequence; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Humans; India; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Nalidixic Acid; Ofloxacin; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Quinolones; Salmonella typhi | 1996 |
Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after intravenous and intramuscular administrations in sheep.
Topics: Analysis of Variance; Animals; Anti-Infective Agents; Biological Availability; Ciprofloxacin; Cross-Over Studies; Enrofloxacin; Female; Fluoroquinolones; Half-Life; Injections, Intramuscular; Injections, Intravenous; Male; Quinolones; Sheep; Time Factors; Tissue Distribution | 1996 |
Disposition of enrofloxacin (Baytril) into the udder after intravenous and intra-arterial injections into dairy cows.
Topics: Animals; Anti-Infective Agents; Cattle; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Injections, Intra-Arterial; Injections, Intravenous; Mammary Glands, Animal; Milk; Quinolones | 1996 |
Compositional analysis surveillance of eleven brands of enrofloxacin including Baytril for veterinary use.
Topics: Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Labeling; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Product Surveillance, Postmarketing; Quinolones; Veterinary Drugs | 1995 |
An audit of ciprofloxacin use in severe life threatening infection at the AKUH.
Topics: Adult; Age Factors; Anti-Infective Agents; Bacterial Infections; Child; Ciprofloxacin; Humans; Infant; Infant, Newborn; Quinolones | 1996 |
[Determination of antimycobacterial activities of fluoroquinolones against clinical isolates of Mycobacterium tuberculosis: comparative determination with egg-based Ogawa and agar-based Middlebrook 7H10 media].
Topics: Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Culture Media; Fluoroquinolones; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Quinolones | 1996 |
Effect of growth conditions on antimicrobial activity of DU-6859a and its bactericidal activity determined by the killing curve method.
Topics: Anti-Infective Agents; Cell Division; Ciprofloxacin; Culture Media; Culture Media, Serum-Free; Drug Resistance, Microbial; Escherichia coli; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Kinetics; Levofloxacin; Metals; Microbial Sensitivity Tests; Microscopy, Electron; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Urine | 1996 |
Gyrase mutations in laboratory-selected, fluoroquinolone-resistant mutants of Mycobacterium tuberculosis H37Ra.
Topics: Anti-Infective Agents; Antitubercular Agents; Base Sequence; Cell Wall; Cephaloridine; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Permeability; Quinolones | 1996 |
Uptake and intracellular activity of NM394, a new quinolone, in human polymorphonuclear leukocytes.
Topics: Amino Acids; Anti-Infective Agents; Antimetabolites; Ciprofloxacin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Neutrophils; Nucleic Acids; Ofloxacin; Phagocytosis; Piperazines; Pseudomonas aeruginosa; Quinolones | 1996 |
Quinolone allergy?
Topics: Biopsy; Ciprofloxacin; Dermatitis Herpetiformis; Diagnosis, Differential; Drug Eruptions; Drug Hypersensitivity; Erythema Multiforme; Humans; Male; Middle Aged; Pemphigoid, Bullous; Quinolones; Skin | 1996 |
In vitro activity of trovafloxacin (CP-99,219), sparfloxacin, ciprofloxacin, and fleroxacin against respiratory pathogens.
Topics: Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Moraxella catarrhalis; Naphthyridines; Quinolones; Respiratory Tract Infections; Streptococcus pneumoniae | 1996 |
Comparative uptake of sparfloxacin and ciprofloxacin into human THP 1 monocytic cells.
Topics: Anti-Infective Agents; Cell Line; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Gemfibrozil; Humans; Hydrogen-Ion Concentration; Hypolipidemic Agents; Monocytes; Quinolones | 1996 |
The photomutagenicity of fluoroquinolones in tests for gene mutation, chromosomal aberration, gene conversion and DNA breakage (Comet assay).
Topics: Animals; Anti-Infective Agents; Carcinogens; Chromosome Aberrations; Ciprofloxacin; Cricetinae; DNA Damage; Fleroxacin; Fluoroquinolones; Gene Conversion; Lymphoma; Methoxsalen; Mice; Mitosis; Mutagenicity Tests; Mutagens; Mutation; Photosensitizing Agents; Quinolones; Saccharomyces cerevisiae; Salmonella; Tumor Cells, Cultured; Ultraviolet Rays | 1996 |
Effect of paclitaxel alone or in combination on the intracellular penetration and activity of quinolones in human neutrophils.
Topics: Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Ciprofloxacin; Cisplatin; Doxorubicin; Fluoroquinolones; Humans; Levofloxacin; Neutrophils; Ofloxacin; Paclitaxel; Quinolones; Staphylococcus aureus | 1996 |
[Effect of drugs of the fluoroquinolone series on morphokinetic parameters of the cellular elements of lung tissue].
Topics: Animals; Anti-Infective Agents; Cell Division; Ciprofloxacin; Culture Techniques; Dogs; Fluoroquinolones; Guinea Pigs; Lung; Lymphocytes; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Ofloxacin; Quinolones | 1996 |
Bactericidal activity of the fluoroquinolone DU-6859a alone and in combination with other antimicrobial agents against multiresistant enterococci.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; Drug Antagonism; Drug Combinations; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Synergism; Enterococcus; Fluoroquinolones; Genetic Variation; Gentamicins; Lactams; Microbial Sensitivity Tests; Novobiocin; Quinolones; Rifampin | 1996 |
Characterisation of DNA gyrase and measurement of drug accumulation in clinical isolates of Acinetobacter baumannii resistant to fluoroquinolones.
Topics: Acinetobacter; Anti-Infective Agents; Ciprofloxacin; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Pefloxacin; Quinolones | 1996 |
The plasma kinetics and tissue distribution of enrofloxacin and its metabolite ciprofloxacin in the Muscovy duck.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Ciprofloxacin; Ducks; Enrofloxacin; Fluoroquinolones; Injections, Intramuscular; Male; Metabolic Clearance Rate; Quinolones; Time Factors; Tissue Distribution | 1997 |
Quinolones share a common interaction domain on topoisomerase II with other DNA cleavage-enhancing antineoplastic drugs.
Topics: Amsacrine; Animals; Anti-Infective Agents; Antineoplastic Agents; Binding Sites; CHO Cells; Ciprofloxacin; Cricetinae; DNA Topoisomerases, Type II; DNA, Superhelical; Drosophila melanogaster; Electrophoresis, Agar Gel; Enzyme Activation; Etoposide; Fluoroquinolones; Genistein; Isoflavones; Kinetics; Molecular Structure; Quinolones | 1997 |
Effect of 6-fluoro-8-methoxy quinolone (AM-1155) against chronic airway infection with Pseudomonas aeruginosa in a rat model.
Topics: Animals; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Disease Models, Animal; Fluoroquinolones; Gatifloxacin; Immunoglobulin A; Immunoglobulin G; Male; Piperazines; Pseudomonas Infections; Quinolones; Rats; Rats, Sprague-Dawley; Tracheal Diseases | 1997 |
Comparative therapeutic efficacy of clinafloxacin in leucopenic mice.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Female; Fluoroquinolones; Leukopenia; Methicillin Resistance; Mice; Quinolones; Staphylococcal Infections | 1997 |
Excellent activity of newer quinolones on Legionella pneumophila in J774 macrophages.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacteriological Techniques; Ciprofloxacin; Colony Count, Microbial; Erythromycin; Fluoroquinolones; Gentamicins; Legionella pneumophila; Legionnaires' Disease; Macrophages; Mice; Penicillins; Quinolones; Tumor Cells, Cultured | 1997 |
Fluoroquinolone antibacterials enhance UVA-induced skin tumors.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Female; Fleroxacin; Fluoroquinolones; Mice; Nalidixic Acid; Neoplasms, Radiation-Induced; Ofloxacin; Quinolones; Skin Neoplasms; Ultraviolet Rays | 1997 |
Quinolone antibacterials: a new class of photochemical carcinogens.
Topics: Animals; Anti-Infective Agents; Carcinoma, Squamous Cell; Ciprofloxacin; Dermatitis, Phototoxic; Fleroxacin; Fluoroquinolones; Methoxsalen; Mice; Mice, Hairless; Nalidixic Acid; Neoplasms, Radiation-Induced; Ofloxacin; Papilloma; Quinolones; Skin Neoplasms | 1997 |
Multicentre in-vitro evaluation of the susceptibility of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis to ciprofloxacin, clarithromycin, co-amoxiclav and sparfloxacin.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Clarithromycin; Clavulanic Acids; Drug Evaluation; Drug Therapy, Combination; Fluoroquinolones; Haemophilus influenzae; Microbial Sensitivity Tests; Moraxella catarrhalis; Quinolones; Streptococcus pneumoniae | 1997 |
[Use of fluoroquinolones in rheumatology].
Topics: Adolescent; Adult; Anti-Infective Agents; Ciprofloxacin; Drug Tolerance; Female; Fluoroquinolones; Follow-Up Studies; Humans; Male; Middle Aged; Pefloxacin; Quinolones; Rheumatic Diseases; Time Factors | 1996 |
Antibacterial activities of grepafloxacin, ciprofloxacin, ofloxacin and fleroxacin.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Mutation; Ofloxacin; Piperazines; Quinolones | 1997 |
Enhanced hematopoiesis in sublethally irradiated mice treated with various quinolones.
Topics: Animals; Anti-Infective Agents; Bone Marrow; Cells, Cultured; Ciprofloxacin; Cobalt Radioisotopes; Colony-Forming Units Assay; Culture Media, Conditioned; Fleroxacin; Fluoroquinolones; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cells; Hemoglobins; Interleukin-3; Leukocyte Count; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Norfloxacin; Ofloxacin; Quinolones; Whole-Body Irradiation | 1997 |
High-level fluoroquinolone resistance in Streptococcus pneumoniae requires mutations in parC and gyrA.
Topics: 4-Quinolones; Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Genes, Bacterial; Mutation; Pefloxacin; Quinolones; Sequence Analysis, DNA; Streptococcus pneumoniae; Transformation, Genetic | 1996 |
The activity of the methylpiperazinyl fluoroquinolone CG 5501: a comparison with other fluoroquinolones.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacteroides fragilis; Chlamydia; Ciprofloxacin; Clarithromycin; Doxycycline; Enterobacter; Erythromycin; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Haemophilus influenzae; Microbial Sensitivity Tests; Naphthyridines; Piperazines; Pseudomonas aeruginosa; Quinolones; Streptococcus pneumoniae | 1997 |
In-vitro and in-vivo activities of DW-116, a new fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Dose-Response Relationship, Drug; Enterococcus faecalis; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Male; Methicillin Resistance; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus | 1997 |
Is Escherichia coli ATCC 25922 useful for monitoring broth microdilution tests of fluoroquinolones?
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones; Reproducibility of Results | 1997 |
Comparative in vitro activities of DU-6859a, levofloxacin, ofloxacin, sparfloxacin, and ciprofloxacin against 387 aerobic and anaerobic bite wound isolates.
Topics: Animals; Anti-Infective Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bites and Stings; Cats; Ciprofloxacin; Dogs; Fluoroquinolones; Haplorhini; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Swine; Wound Infection | 1997 |
Bioavailability of enrofloxacin after oral administration to fed and fasted pigs.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Biological Availability; Ciprofloxacin; Enrofloxacin; Fasting; Female; Fluoroquinolones; Food; Male; Quinolones; Swine | 1997 |
Participation of reactive oxygen species in phototoxicity induced by quinolone antibacterial agents.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; DNA; DNA Damage; Enoxacin; Fluoroquinolones; Free Radical Scavengers; Hematoporphyrins; Molecular Structure; Ofloxacin; Oxygen; Photosensitizing Agents; Quinolones; Reactive Oxygen Species; Spectroscopy, Near-Infrared; Superoxides | 1997 |
Quinolone antibiotic photodynamic production of 8-oxo-7, 8-dihydro-2'-deoxyguanosine in cultured liver epithelial cells.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Infective Agents; Cell Line; Chromatography, High Pressure Liquid; Ciprofloxacin; Deoxyguanosine; Electrochemistry; Epithelial Cells; Epithelium; Fluoroquinolones; Liver; Photosensitizing Agents; Quinolones; Rats; Spectrophotometry, Ultraviolet | 1997 |
Bactericidal index: a new way to assess quinolone bactericidal activity in vitro.
Topics: Anti-Infective Agents; Ciprofloxacin; Enterococcus faecalis; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones | 1997 |
The bactericidal activity of levofloxacin compared with ofloxacin, D-ofloxacin, ciprofloxacin, sparfloxacin and cefotaxime against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Cefotaxime; Ciprofloxacin; Colony Count, Microbial; Fluoroquinolones; Levofloxacin; Ofloxacin; Quinolones; Streptococcus pneumoniae | 1997 |
In-vitro activity of trovafloxacin against clinical bacterial isolates from patients with cancer.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Neoplasms; Norfloxacin; Ofloxacin; Quinolones | 1997 |
Time-kill study of the activity of trovafloxacin compared with ciprofloxacin, sparfloxacin, metronidazole, cefoxitin, piperacillin and piperacillin/tazobactam against six anaerobes.
Topics: Anti-Infective Agents; Bacteroides; Bacteroides fragilis; Cefoxitin; Ciprofloxacin; Clostridium perfringens; Fluoroquinolones; Fusobacterium; Gram-Negative Anaerobic Bacteria; Metronidazole; Microbial Sensitivity Tests; Naphthyridines; Penicillanic Acid; Peptostreptococcus; Piperacillin; Prevotella melaninogenica; Quinolones; Tazobactam | 1997 |
Disposition of enrofloxacin and its metabolite ciprofloxacin after intramuscular injection in juvenile Burmese pythons (Python molurus bivittatus).
Topics: Animals; Anti-Infective Agents; Boidae; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Half-Life; Injections, Intramuscular; Male; Quinolones | 1997 |
In-vitro activity of clinafloxacin, trovafloxacin, and ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Quinolones | 1997 |
In-vitro susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis and Ureaplasma urealyticum to clinafloxacin, PD 131628, ciprofloxacin and comparator drugs.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Clindamycin; Erythromycin; Fluoroquinolones; In Vitro Techniques; Microbial Sensitivity Tests; Mycoplasma hominis; Mycoplasma pneumoniae; Naphthyridines; Quinolones; Tetracycline; Ureaplasma urealyticum | 1997 |
Active efflux as a mechanism of resistance to ciprofloxacin in Streptococcus pneumoniae.
Topics: 4-Quinolones; Acriflavine; Adenosine Triphosphate; Anti-Infective Agents; Anti-Infective Agents, Local; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cetrimonium; Cetrimonium Compounds; Ciprofloxacin; Drug Resistance, Microbial; Ethidium; Fluoroquinolones; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Pefloxacin; Phenotype; Quinolones; Streptococcus pneumoniae; Transformation, Bacterial | 1997 |
Pharmacokinetics of enrofloxacin in horses after single intravenous and intramuscular administration.
Topics: Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Creatine Kinase; Enrofloxacin; Female; Fluoroquinolones; Half-Life; Horses; Injections, Intramuscular; Injections, Intravenous; Quinolones | 1997 |
In vitro and in vivo antibacterial efficacies of CFC-222, a new fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Culture Media; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1997 |
In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pefloxacin; Quinolones; Respiratory Tract Infections | 1997 |
A comprehensive model for enrofloxacin to ciprofloxacin transformation and disposition in dog.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Biological Availability; Biotransformation; Body Fluid Compartments; Ciprofloxacin; Dogs; Enrofloxacin; Female; Fluoroquinolones; Liver; Male; Models, Biological; Quinolones; Tissue Distribution | 1997 |
The effects of macrolide and quinolone antibiotics in methicillin-resistant Staphylococcus aureus biofilm growth.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Catheterization; Ciprofloxacin; Erythromycin; Fluoroquinolones; Methicillin Resistance; Quinolones; Staphylococcus aureus | 1997 |
Clinafloxacin (CL 960) is superior to standard therapeutics in the treatment of murine listeriosis and salmonellosis.
Topics: Ampicillin; Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Female; Fluoroquinolones; Listeriosis; Mice; Mice, Nude; Microbial Sensitivity Tests; Penicillins; Quinolones; Salmonella enterica; Salmonella Infections, Animal; Salmonella typhimurium | 1997 |
Comparative antistreptococcal activity of two newer fluoroquinolones, levofloxacin and sparfloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Ofloxacin; Pneumococcal Infections; Quinolones; Streptococcal Infections; Streptococcus; Streptococcus pneumoniae | 1997 |
Limited capacity of neonatal rabbits to eliminate enrofloxacin and ciprofloxacin.
Topics: Aging; Animals; Animals, Newborn; Animals, Suckling; Anti-Infective Agents; Blood Proteins; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Injections, Intraperitoneal; Male; Models, Biological; Protein Binding; Quinolones; Rabbits; Random Allocation | 1997 |
Comparison of the antibacterial activities of the quinolones Bay 12-8039, gatifloxacin (AM 1155), trovafloxacin, clinafloxacin, levofloxacin and ciprofloxacin.
Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Quinolones; Staphylococcus aureus | 1997 |
Pharmacokinetics of enrofloxacin in newborn and one-week-old calves.
Topics: Aging; Animals; Animals, Newborn; Anti-Infective Agents; Area Under Curve; Cattle; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Half-Life; Injections, Intravenous; Metabolic Clearance Rate; Quinolones | 1997 |
Pneumococcal resistance in the UK.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporins; Chloramphenicol; Ciprofloxacin; Drug Resistance, Multiple; Fluoroquinolones; Humans; Macrolides; Microbial Sensitivity Tests; Northern Ireland; Ofloxacin; Oxacillin; Penicillin Resistance; Penicillins; Piperazines; Pneumococcal Infections; Quinolones; Retrospective Studies; Streptococcus pneumoniae; Tetracycline | 1997 |
The activity of grepafloxacin against respiratory pathogens in the UK.
Topics: Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; England; Fluoroquinolones; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Moraxella catarrhalis; Penicillin Resistance; Penicillins; Piperazines; Quinolones; Respiratory Tract Infections; Retrospective Studies; Streptococcus pneumoniae | 1997 |
Pharmacokinetics of enrofloxacin in chicken.
Topics: Animals; Anti-Infective Agents; Campylobacter; Chickens; Ciprofloxacin; Drug Resistance, Microbial; Enrofloxacin; Fluoroquinolones; Quinolones; Research Design | 1997 |
In-vitro and in-vivo antibacterial activity of CFC-222, a new fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1998 |
Photosensitivity induced by lomefloxacin with cross-photosensitivity to ciprofloxacin and fleroxacin.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Dermatitis, Photoallergic; Fleroxacin; Fluoroquinolones; Humans; Male; Quinolones | 1998 |
Comparative therapeutic efficacy of clinafloxacin in a Pseudomonas aeruginosa mouse renal abscess model.
Topics: Abscess; Animals; Anti-Infective Agents; Area Under Curve; Ceftazidime; Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Colony Count, Microbial; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Fluoroquinolones; Half-Life; Imipenem; Kidney; Kidney Diseases; Mice; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones; Treatment Outcome | 1998 |
Serotyping of quinolone-resistant Neisseria gonorrhoeae isolates with alterations in GyrA and ParC.
Topics: Amino Acid Substitution; Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Mutation; Neisseria gonorrhoeae; Quinolones; Serotyping | 1998 |
In vitro activities of clinafloxacin against contemporary clinical bacterial isolates from 10 North American centers.
Topics: Anti-Infective Agents; Cefoxitin; Cephamycins; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Quinolones | 1998 |
In vitro activities of six fluoroquinolones against Canadian isolates of vancomycin-sensitive and vancomycin-resistant Enterococcus species.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Canada; Ciprofloxacin; Drug Resistance, Microbial; Enterococcus; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Vancomycin | 1998 |
Pharmacodynamic activities of ciprofloxacin and sparfloxacin in a murine pneumococcal pneumonia model: relevance for drug efficacy.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Female; Fluoroquinolones; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Pneumonia, Pneumococcal; Quinolones; Streptococcus pneumoniae | 1998 |
In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to BAY 12-8039, trovafloxacin, and ciprofloxacin.
Topics: Anti-Infective Agents; Aza Compounds; Bordetella; Bordetella pertussis; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Quinolines; Quinolones | 1998 |
Efficacy of difloxacin in growing broiler chickens for the control of infection due to pathogenic Mycoplasma gallisepticum.
Topics: Animals; Anti-Infective Agents; Chickens; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Male; Mycoplasma; Mycoplasma Infections; Poultry Diseases; Quinolones | 1998 |
Bacterial eradication by clinafloxacin, CI-990, and ciprofloxacin employing MBC test, in-vitro time-kill and in-vivo time-kill studies.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Naphthyridines; Quinolones | 1998 |
Intracellular activity of ciprofloxacin and moxifloxacin, a new 8-methoxyquinolone, against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Aza Compounds; Cells, Cultured; Ciprofloxacin; Fluoroquinolones; Humans; Leukocytes, Mononuclear; Methicillin Resistance; Microbial Sensitivity Tests; Moxifloxacin; Phagocytosis; Quinolines; Quinolones; Staphylococcus aureus | 1998 |
Effects of fluoroquinolones and magnesium deficiency in murine limb bud cultures.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; Extremities; Fleroxacin; Fluoroquinolones; Magnesium Deficiency; Mice; Microscopy, Electron; Ofloxacin; Pefloxacin; Quinolones | 1998 |
Uptake of fluoroquinolones in human monocytes isolated from peripheral blood.
Topics: Anti-Infective Agents; Cell Adhesion; Cell Separation; Ciprofloxacin; Flow Cytometry; Fluoroquinolones; Humans; Monocytes; Ofloxacin; Quinolones | 1998 |
The effects of increasing levels of quinolone resistance on in-vitro activity of four quinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Ofloxacin; Quinolones | 1998 |
[Trends and changes in antimicrobial resistance of clinical isolates from 11 hospitals in Beijing area].
Topics: Anti-Infective Agents; Ceftazidime; Cephalosporins; China; Ciprofloxacin; Drug Resistance, Microbial; Escherichia coli; Humans; Klebsiella; Quinolones; Streptococcus pneumoniae | 1997 |
In-vitro activity of three fluoroquinolones, cefotaxime and clindamycin against staphylococci.
Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Cefotaxime; Cephalosporins; Ciprofloxacin; Clindamycin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Staphylococcal Infections; Staphylococcus | 1995 |
Antimicrobial activity of gatifloxacin tested against 1676 strains of ciprofloxacin-resistant gram-positive cocci isolated from patient infections in North and South America.
Topics: Anti-Infective Agents; Antitubercular Agents; Bacteriological Techniques; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Naphthyridines; North America; Quinolones; South America | 1998 |
Antistaphylococcal and antistreptococcal killing kinetics of ciprofloxacin, ofloxacin, sparfloxacin, and trovafloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Staphylococcal Infections; Staphylococcus aureus; Streptococcal Infections; Streptococcus pneumoniae; Streptococcus pyogenes | 1998 |
Comparison of the complexation of fluoroquinolone antimicrobials with metal ions by nuclear magnetic resonance spectroscopy.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Levofloxacin; Magnetic Resonance Spectroscopy; Metals; Ofloxacin; Quinolones; Solutions; Temperature | 1999 |
Comparative activities of clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, ofloxacin, sparfloxacin, and trovafloxacin and nonquinolones linozelid, quinupristin-dalfopristin, gentamicin, and vancomycin against clinical isolates of ciprofloxacin-re
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Quinolones; Staphylococcus aureus; Vancomycin; Virginiamycin | 1999 |
Synthesis and methemoglobin toxicity of the amides of 6/7 mono or disubstituted quinolone.
Topics: Amides; Animals; Anti-Infective Agents; Ciprofloxacin; Cytochrome-B(5) Reductase; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Methemoglobin; Methemoglobinemia; Norfloxacin; Ofloxacin; Quinolones; Structure-Activity Relationship | 1999 |
Chromosomal aberrations in human lymphocytes exposed in vitro to enrofloxacin and ciprofloxacin.
Topics: Adult; Anti-Infective Agents; Cells, Cultured; Chromosome Aberrations; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Humans; In Vitro Techniques; Lymphocytes; Male; Middle Aged; Quinolones | 1999 |
Implementing an automatic fluoroquinolone therapeutic interchange program in a community hospital.
Topics: Ciprofloxacin; Drug Costs; Florida; Formularies, Hospital as Topic; Hospital Bed Capacity, 100 to 299; Hospitals, Community; Quinolones; Therapeutic Equivalency | 1992 |
In vitro and in vivo antimicrobial activities of T-3811ME, a novel des-F(6)-quinolone.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Indoles; Injections, Subcutaneous; Isoindoles; Male; Mice; Naphthyridines; Ofloxacin; Quinolones | 1999 |
Electrophoretic behaviour of quinolones in capillary electrophoresis. Effect of pH and evaluation of ionization constants.
Topics: Anti-Infective Agents; Chemical Phenomena; Chemistry, Physical; Ciprofloxacin; Electrophoresis, Capillary; Fluoroquinolones; Hydrogen-Ion Concentration; Ions; Mathematics; Models, Chemical; Molecular Structure; Norfloxacin; Quinolones; Solutions; Water | 1999 |
Simultaneous determination of enrofloxacin and ciprofloxacin in animal biological fluids by high-performance liquid chromatography. Application in pharmacokinetic studies in pig and rabbit.
Topics: Animals; Anti-Infective Agents; Body Fluids; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Quinolones; Rabbits; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Swine | 1999 |
Quinolone accumulation by Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli.
Topics: Anti-Infective Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Ciprofloxacin; Diffusion; Dose-Response Relationship, Drug; Enoxacin; Enrofloxacin; Escherichia coli; Fluorescence; Fluoroquinolones; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Nalidixic Acid; Pseudomonas aeruginosa; Quinolones; Spheroplasts; Staphylococcus aureus; Temperature | 1999 |
Simultaneous determination of enrofloxacin and its primary metabolite, ciprofloxacin, in plasma by HPLC with fluorescence detection.
Topics: Anti-Infective Agents; Calibration; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Indicators and Reagents; Quinolones; Reproducibility of Results; Spectrometry, Fluorescence | 1999 |
Pharmacokinetics of enrofloxacin and danofloxacin in plasma, inflammatory exudate, and bronchial secretions of calves following subcutaneous administration.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Bronchi; Cattle; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Exudates and Transudates; Fluoroquinolones; Inflammation; Injections, Subcutaneous; Male; Mucus; Quinolones | 1999 |
Determination of ciprofloxacin and enrofloxacin in edible animal tissues by terbium-sensitized luminescence.
Topics: Animals; Anti-Infective Agents; Chickens; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Food Contamination; Humans; Luminescent Measurements; Meat; Quinolones; Trout | 1998 |
Comparative pharmacokinetics of enrofloxacin and ciprofloxacin in chickens.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Injections, Intravenous; Quinolones | 1999 |
Comparative studies of mutations in animal isolates and experimental in vitro- and in vivo-selected mutants of Salmonella spp. suggest a counterselection of highly fluoroquinolone-resistant strains in the field.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Chickens; Ciprofloxacin; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Enrofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Phenotype; Polymerase Chain Reaction; Quinolones; Salmonella typhimurium; Serotyping | 1999 |
Pharmacokinetic variables and tissue residues of enrofloxacin and ciprofloxacin in healthy pigs.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Chromatography, High Pressure Liquid; Ciprofloxacin; Cross-Over Studies; Drug Residues; Enrofloxacin; Fluoroquinolones; Injections, Intramuscular; Injections, Intravenous; Male; Metabolic Clearance Rate; Models, Biological; Quinolones; Swine | 1999 |
Quinolones inhibit DNA religation mediated by Staphylococcus aureus topoisomerase IV. Changes in drug mechanism across evolutionary boundaries.
Topics: Anti-Infective Agents; Biological Evolution; Ciprofloxacin; DNA Damage; DNA Repair; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Escherichia coli; Etoposide; Fluoroquinolones; Gram-Positive Bacteria; Kinetics; Quinolones; Staphylococcus aureus | 1999 |
In vitro phototoxicity of new quinolones: production of active oxygen species and photosensitized lipid peroxidation.
Topics: Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; DNA Damage; Fleroxacin; Fluoroquinolones; Humans; Lipid Peroxidation; Norfloxacin; Ofloxacin; Quinolones; Reactive Oxygen Species; Squalene; Time Factors; Ultraviolet Rays | 1999 |
Comparative studies on topical lomefloxacin and ciprofloxacin on ocular kinetic and experimental corneal ulcer.
Topics: Administration, Topical; Animals; Anti-Infective Agents; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Corneal Ulcer; Eye; Female; Fluoroquinolones; Hydrogen-Ion Concentration; Male; Quinolones; Rabbits; Staphylococcal Infections; Staphylococcus aureus | 1999 |
Comparative antimicrobial activities of the newly synthesized quinolone WQ-3034, levofloxacin, sparfloxacin, and ciprofloxacin against Mycobacterium tuberculosis and Mycobacterium avium complex.
Topics: 4-Quinolones; Aminopyridines; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Rifamycins | 2000 |
Engineering the specificity of antibacterial fluoroquinolones: benzenesulfonamide modifications at C-7 of ciprofloxacin change its primary target in Streptococcus pneumoniae from topoisomerase IV to gyrase.
Topics: Anti-Infective Agents; Benzenesulfonamides; Catalysis; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Design; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mutation; Quinolones; Streptococcus pneumoniae; Sulfonamides; Topoisomerase II Inhibitors | 2000 |
Pharmacokinetics of enrofloxacin administered intravenously and orally to foals.
Topics: Administration, Oral; Animals; Animals, Newborn; Anti-Infective Agents; Area Under Curve; Chromatography, High Pressure Liquid; Ciprofloxacin; Computer Simulation; Cross-Over Studies; Enrofloxacin; Fluoroquinolones; Half-Life; Horses; Injections, Intravenous; Quinolones; Regression Analysis | 2000 |
Efficacy of difloxacin in calves experimentally infected with Mannheimia haemolytica.
Topics: Animals; Anti-Infective Agents; Body Temperature; Cattle; Cattle Diseases; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Lung; Male; Mannheimia haemolytica; Pasteurella Infections; Quinolones; Random Allocation; Weight Gain | 2000 |
[The chemotherapeutic efficacy of ciprofloxacin and lomefloxacin in the inhalation method of infecting white mice with tularemia].
Topics: Aerosols; Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; Drug Evaluation, Preclinical; Fluoroquinolones; Mice; Particle Size; Quinolones; Research Design; Tularemia | 2000 |
Application of principal component regression to luminescence data for the screening of ciprofloxacin and enrofloxacin in animal tissues.
Topics: Animals; Anti-Infective Agents; Calibration; Chickens; Ciprofloxacin; Drug Residues; Enrofloxacin; Fluoroquinolones; Meat; Quinolones; Spectrum Analysis; Trout; Veterinary Drugs | 2000 |
Separation and quantification of two fluoroquinolones in serum by on-line high-performance immunoaffinity chromatography.
Topics: Anti-Infective Agents; Chromatography, Affinity; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Immunoassay; Quinolones | 2000 |
FDA hastening withdrawal of fluoroquinolone approvals for poultry.
Topics: Animals; Anti-Infective Agents; Campylobacter; Campylobacter Infections; Chickens; Ciprofloxacin; Drug Approval; Enrofloxacin; Fluoroquinolones; Quinolones; Risk Assessment; Turkeys; United States; United States Food and Drug Administration | 2000 |
A thermodynamic study of complexation of ciprofloxacin and lomefloxacin with aluminium ion.
Topics: Aluminum; Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Drug Stability; Entropy; Fluoroquinolones; Quinolones; Thermodynamics | 2000 |
Effects of endotoxin-induced fever and probenecid on disposition of enrofloxacin and its metabolite ciprofloxacin after intravascular administration of enrofloxacin in goats.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Drug Interactions; Endotoxins; Enrofloxacin; Female; Fever; Fluoroquinolones; Goats; Half-Life; Injections, Intravenous; Metabolic Clearance Rate; Probenecid; Quinolones; Uricosuric Agents | 2000 |
Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones.
Topics: Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Cytoplasm; Fibroblasts; Fluoroquinolones; Humans; Mitochondria; Norfloxacin; Ofloxacin; Photosensitizing Agents; Quinolones; Skin | 2000 |
Characterization of high-level fluoroquinolone resistance in Escherichia coli O78:K80 isolated from turkeys.
Topics: Amino Acid Substitution; Animals; Anti-Infective Agents; Bacterial Proteins; Blotting, Western; Carrier Proteins; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Bacterial; Drug Resistance, Microbial; Enrofloxacin; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Lipoproteins; Membrane Proteins; Membrane Transport Proteins; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Mutation; Nalidixic Acid; Quinolizines; Quinolones; RNA, Ribosomal, 16S; RNA, Ribosomal, 23S; Turkeys | 2001 |
Activity and spectrum of BMS 284756, a new des-F (6) quinolone, tested against strains of ciprofloxacin-resistant Gram-positive cocci.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Indoles; Microbial Sensitivity Tests; Quinolones | 2001 |
Quinolone resistance in Staphylococci: activities of new nonfluorinated quinolones against molecular targets in whole cells and clinical isolates.
Topics: Anti-Infective Agents; Ciprofloxacin; Coagulase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Drug Resistance, Multiple; Humans; Kinetics; Methicillin Resistance; Microbial Sensitivity Tests; Mutation; Quinolones; Staphylococcal Infections; Staphylococcus aureus; Topoisomerase II Inhibitors | 2001 |
Microbiological and chemical detection of incurred penicillin G, oxytetracycline, enrofloxacin and ciprofloxacin residues in bovine and porcine tissues.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cattle; Ciprofloxacin; Drug Residues; Enrofloxacin; Fluoroquinolones; Humans; Kidney; Muscles; Oxytetracycline; Penicillin G; Quinolones; Swine | 2000 |
In vitro evidence for effects of magnesium supplementation on quinolone-treated horse and dog chondrocytes.
Topics: Animals; Anti-Infective Agents; Cartilage, Articular; Cell Adhesion; Cell Division; Cell Size; Cells, Cultured; Chondrocytes; Ciprofloxacin; Dietary Supplements; Dogs; Enrofloxacin; Female; Fluoroquinolones; Horses; Immunohistochemistry; Ki-67 Antigen; Magnesium; Quinolones | 2001 |
The antibiotic microcin B17 is a DNA gyrase poison: characterisation of the mode of inhibition.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; Bacterial Toxins; Bacteriocins; Calcium; Ciprofloxacin; Coumarins; Cytotoxins; DNA Gyrase; DNA Replication; DNA Topoisomerases, Type II; DNA-Directed DNA Polymerase; DNA, Superhelical; Escherichia coli; Kinetics; Models, Molecular; Mutation; Nucleic Acid Synthesis Inhibitors; Peptides; Protein Conformation; Quinolones; Substrate Specificity; Topoisomerase II Inhibitors; Yeasts | 2001 |
Determination of fluoroquinolones in serum using an on-line clean-up column coupled to high-performance immunoaffinity-reversed-phase liquid chromatography.
Topics: Animals; Anti-Infective Agents; Cattle; Chromatography, Affinity; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Immunochemistry; Molecular Structure; Quinolones | 2001 |
Lomefloxacin is an effective treatment of experimental bacterial keratitis.
Topics: Administration, Topical; Animals; Anti-Infective Agents; Bacteria; Ciprofloxacin; Colony Count, Microbial; Corneal Stroma; Drug Evaluation, Preclinical; Eye Infections, Bacterial; Fluoroquinolones; Keratitis; Microbial Sensitivity Tests; Models, Animal; Ophthalmic Solutions; Quinolones; Rabbits | 2001 |
[Determination of enrofloxacin and it's main metabolite in animal plasma by reversed-phase ion-pair high performance liquid chromatography].
Topics: Animals; Anti-Infective Agents; Cattle; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Quinolones | 1998 |
Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after intramuscular administration of enrofloxacin in goats.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Goats; Half-Life; Injections, Intramuscular; Quinolones | 2001 |
Fixed drug eruption from quinolones with a positive lesional patch test to ciprofloxacin.
Topics: Adult; Ciprofloxacin; Drug Eruptions; Female; Hand Dermatoses; Humans; Patch Tests; Quinolones; Skin | 2001 |
Effects of enrofloxacin and ciprofloxacin hydrochloride on canine and equine chondrocytes in culture.
Topics: Animals; Anti-Infective Agents; Cartilage, Articular; Cell Adhesion; Cell Survival; Cells, Cultured; Chondrocytes; Ciprofloxacin; Dogs; Enrofloxacin; Fluoroquinolones; Horses; Magnesium; Microscopy, Electron; Microscopy, Fluorescence; Quinolones | 2001 |
Simple high-performance liquid chromatographic assay for the determination of ciprofloxacin in human plasma with ultraviolet detection.
Topics: Anti-Infective Agents; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Humans; Molecular Structure; Quinolones; Reproducibility of Results | 2001 |
Activity of BMS284756 against 2,681 recent clinical isolates of Haemophilus influenzae and Moraxella catarrhalis: Report from The SENTRY Antimicrobial Surveillance Program (2000) in Europe, Canada and the United States.
Topics: Anti-Infective Agents; Aza Compounds; Canada; Ciprofloxacin; Europe; Fluoroquinolones; Gatifloxacin; Haemophilus influenzae; Humans; Indoles; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; United States | 2001 |
Immunomodulatory effects of moxifloxacin in comparison to ciprofloxacin and G-CSF in a murine model of cyclophosphamide-induced leukopenia.
Topics: Animals; Anti-Infective Agents; Aza Compounds; Bone and Bones; Bone Marrow Cells; Cell Count; Ciprofloxacin; Culture Media, Conditioned; Culture Techniques; Cyclophosphamide; Cytokines; Disease Models, Animal; Fluoroquinolones; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; Humans; Immunity; Interleukin-6; Leukocyte Count; Leukopenia; Lung; Male; Mice; Mice, Inbred BALB C; Moxifloxacin; Quinolines; Quinolones; Spleen; Urinary Bladder | 2001 |
Determination of residues of enrofloxacin and its metabolite ciprofloxacin in biological materials by capillary electrophoresis.
Topics: Animals; Anti-Infective Agents; Calibration; Chickens; Ciprofloxacin; Drug Residues; Electrophoresis, Capillary; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Muscles; Quinolones; Reference Standards | 2001 |
Quinolone resistance in potentially pathogenic and non-pathogenic Escherichia coli strains isolated from healthy ruminants.
Topics: Animals; Anti-Infective Agents; Cattle; Ciprofloxacin; Enrofloxacin; Escherichia coli; Fluoroquinolones; Goats; Microbial Sensitivity Tests; Nalidixic Acid; Quinolones; Ruminants; Sheep | 2001 |
Comparison of the in vitro activities of BMS-284756 and four fluoroquinolones against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Moxifloxacin; Norfloxacin; Quinolines; Quinolones; Streptococcus pneumoniae | 2001 |
[Degradation of liquid preparations of four fluoroquinolones by factorial experiment. ].
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Light; Norfloxacin; Ofloxacin; Quinolones | 1997 |
[Studies on pyridonecarboxylic acids as antibacterial agents. XII. Synthesis and antibacterial activity of 6-chloro-1-cyclopropyl-7-(1-piperazinyl)-1, 4-dihydro-4-oxo-quinoline-3-carboxylic acid and analogues].
Topics: Animals; Anti-Infective Agents; Carboxylic Acids; Ciprofloxacin; Escherichia coli; Mice; Norfloxacin; Pseudomonas aeruginosa; Pyridones; Quinolones; Staphylococcal Infections; Staphylococcus aureus | 1997 |
Staphylococcus aureus mutants selected by BMS-284756.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA, Bacterial; Drug Resistance, Microbial; Fluoroquinolones; Indoles; Mutation; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcus aureus | 2001 |
In vitro antibacterial activity of enrofloxacin and ciprofloxacin in combination against Escherichia coli and staphylococcal clinical isolates from dogs.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dog Diseases; Dogs; Drug Combinations; Drug Synergism; Enrofloxacin; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones; Staphylococcal Infections; Staphylococcus aureus | 2001 |
Spectrophotometric determination of ciprofloxacin, enrofloxacin and pefloxacin through charge transfer complex formation.
Topics: Anti-Infective Agents; Benzoquinones; Capsules; Ciprofloxacin; Electron Transport; Enrofloxacin; Ethylenes; Fluoroquinolones; Nitriles; Pefloxacin; Quality Control; Quinolones; Reproducibility of Results; Spectrophotometry; Spectrophotometry, Ultraviolet; Statistics as Topic; Tablets | 2002 |
Antimicrobial activity of BMS 284756 (T-3811) against Neisseria gonorrhoeae tested by three methods.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gonorrhea; Humans; Indoles; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillin Resistance; Penicillins; Quinolones | 2001 |
Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin in goats given enrofloxacin alone and in combination with probenecid.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Area Under Curve; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Goats; Half-Life; Injections, Intramuscular; Probenecid; Quinolones; Uricosuric Agents | 2002 |
Antipneumococcal activity of BMS 284756 compared to those of six other agents.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Penicillin Resistance; Quinolones; Streptococcus pneumoniae; Time Factors | 2002 |
Elimination of mycoplasma from leukemia-lymphoma cell lines using antibiotics.
Topics: Algorithms; Anti-Bacterial Agents; Anti-Infective Agents; Cell Culture Techniques; Ciprofloxacin; Culture Media; Diterpenes; Drug Resistance; Drug Resistance, Multiple, Bacterial; Enrofloxacin; Fluoroquinolones; Humans; Leukemia; Lymphoma; Minocycline; Mycoplasma; Quinolones; Suspensions; Tumor Cells, Cultured | 2002 |
Using nonaqueous capillary electrophoresis to analyze several quinolones in pig kidney samples.
Topics: Animals; Anti-Infective Agents; Calibration; Ciprofloxacin; Electrophoresis, Capillary; Enrofloxacin; Fluoroquinolones; Kidney; Molecular Structure; Oxolinic Acid; Quinolizines; Quinolones; Swine | 2002 |
Comparative serum pharmacokinetics of the fluoroquinolones enrofloxacin, difloxacin, marbofloxacin, and orbifloxacin in dogs after single oral administration.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Cross-Over Studies; Dogs; Enrofloxacin; Female; Fluoroquinolones; Male; Microbial Sensitivity Tests; Quinolones | 2002 |
Influence of porcine Actinobacillus pleuropneumoniae infection and dexamethasone on the pharmacokinetic parameters of enrofloxacin.
Topics: Actinobacillus Infections; Actinobacillus pleuropneumoniae; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Area Under Curve; Biotransformation; Chromatography, High Pressure Liquid; Ciprofloxacin; Creatinine; Dexamethasone; Drug Interactions; Enrofloxacin; Fluoroquinolones; Male; Quinolones; Swine; Swine Diseases | 2002 |
Comparison of the bactericidal activities and post-antibiotic effects of the Des-F(6)-quinolone BMS-284756, levofloxacin, and ciprofloxacin against methicillin-susceptible and methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Blood Bactericidal Activity; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Indoles; Levofloxacin; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Sensitivity and Specificity; Staphylococcus aureus | 2002 |
Accumulation of ciprofloxacin and lomefloxacinin fluoroquinolone-resistant strains of Escherichia coli.
Topics: 2,4-Dinitrophenol; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Porins; Quinolones | 2002 |
Mechanism of plasmid-mediated quinolone resistance.
Topics: Amino Acid Sequence; Anti-Infective Agents; Biological Assay; Ciprofloxacin; Cloning, Molecular; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance; Escherichia coli; Histidine; Models, Genetic; Molecular Sequence Data; Mutation; Plasmids; Protein Binding; Quinolones; Sequence Homology, Amino Acid | 2002 |
Concentration of enrofloxacin and its metabolite ciprofloxacin in canine matrices of the locomotor system.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Bone and Bones; Chromatography, High Pressure Liquid; Ciprofloxacin; Dogs; Dose-Response Relationship, Drug; Enrofloxacin; Female; Fluoroquinolones; Injections, Subcutaneous; Male; Muscles; Quinolones | 2002 |
Osteoadsorptive bisphosphonate derivatives of fluoroquinolone antibacterials.
Topics: Animals; Anti-Infective Agents; Bone and Bones; Ciprofloxacin; Diphosphonates; Enoxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydrogen-Ion Concentration; In Vitro Techniques; Microbial Sensitivity Tests; Norfloxacin; Piperazines; Quinolones; Rats; Spectrometry, Fluorescence; Structure-Activity Relationship; Swine | 2002 |
Determination of ciprofloxacin, enrofloxacin and flumequine in pig plasma samples by capillary isotachophoresis--capillary zone electrophoresis.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Electrophoresis, Capillary; Enrofloxacin; Fluoroquinolones; Quinolizines; Quinolones; Reproducibility of Results; Sensitivity and Specificity; Swine | 2002 |
A case of pemphigus vulgaris possibly triggered by quinolones.
Topics: Aged; Azathioprine; Biopsy, Needle; Ciprofloxacin; Drug Therapy, Combination; Follow-Up Studies; Humans; Male; Mouth Mucosa; Pemphigus; Prednisolone; Quinolones; Risk Assessment; Severity of Illness Index; Treatment Outcome; Urinary Tract Infections | 2002 |
Single- and multistep selection study of the antipneumococcal activity of BMS-284756 compared to ciprofloxacin, levofloxacin, trovafloxacin and moxifloxacin.
Topics: Anti-Infective Agents; Aza Compounds; Biological Transport; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Indoles; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Streptococcus pneumoniae | 2002 |
Pharmacokinetics after intravenous and oral administration of enrofloxacin in sheep.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Area Under Curve; Biological Availability; Ciprofloxacin; Cross-Over Studies; Enrofloxacin; Female; Fluoroquinolones; Half-Life; Injections, Intravenous; Quinolones; Sheep | 2002 |
Liquid chromatographic determination of fluoroquinolones in egg albumen and egg yolk of laying hens using fluorometric detection.
Topics: Animals; Anti-Infective Agents; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Egg Yolk; Enrofloxacin; Female; Fluorometry; Fluoroquinolones; Ovalbumin; Poultry Diseases; Quality Control; Quinolones; Veterinary Drugs | 2002 |
[Phototoxicity studies of pazufloxacin mesilate, a novel parenteral quinolone antimicrobial agent--in vitro and in vivo studies].
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Female; Fluoroquinolones; Guinea Pigs; Nalidixic Acid; Ofloxacin; Oxazines; Quinolones; Rats; Rats, Sprague-Dawley; Ultraviolet Rays | 2002 |
[Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration].
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; beta-Alanine; Biphenyl Compounds; Cefazolin; Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Convulsants; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Imipenem; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Norfloxacin; Oxazines; Penicillin G; Quinolones; Seizures; Thienamycins | 2002 |
Determination of residues of enrofloxacin and its metabolite ciprofloxacin in chicken muscle by capillary electrophoresis using laser-induced fluorescence detection.
Topics: Animals; Anti-Infective Agents; Calibration; Chickens; Ciprofloxacin; Electrophoresis, Capillary; Enrofloxacin; Fluorescent Dyes; Fluoroquinolones; Food Contamination; Lasers; Muscle, Skeletal; Quinolones; Sensitivity and Specificity; Veterinary Drugs | 2002 |
Effects of the Des-F(6)-quinolone garenoxacin (BMS-284756), in comparison to those of ciprofloxacin and ofloxacin, on joint cartilage in immature rats.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Cartilage Diseases; Cartilage, Articular; Ciprofloxacin; Fluoroquinolones; Indoles; Knee Joint; Ofloxacin; Quinolones; Rats; Rats, Wistar | 2002 |
Comparative articular toxicity of garenoxacin, a novel quinolone antimicrobial agent, in juvenile beagle dogs.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Cartilage, Articular; Ciprofloxacin; Dogs; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Indoles; Injections, Intravenous; Joint Diseases; Male; Norfloxacin; Quinolones; Toxicity Tests | 2002 |
Dual targeting of DNA gyrase and topoisomerase IV: target interactions of garenoxacin (BMS-284756, T-3811ME), a new desfluoroquinolone.
Topics: Alleles; Anti-Infective Agents; Ciprofloxacin; Cloning, Molecular; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gene Expression Regulation, Enzymologic; Indoles; Microbial Sensitivity Tests; Mutation; Plasmids; Quinolones; Staphylococcus aureus; Topoisomerase II Inhibitors | 2002 |
Liquid chromatography analysis of enrofloxacin and ciprofloxacin in chicken blood spotted on filter-paper disks.
Topics: Animals; Anti-Infective Agents; Chickens; Chromatography, Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Paper; Quinolones; Reproducibility of Results; Sensitivity and Specificity | 2002 |
Distribution of enrofloxacin in intestinal tissue and contents of healthy pigs after oral and intramuscular administrations.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Feces; Female; Fluoroquinolones; Injections, Intramuscular; Intestinal Mucosa; Lymph Nodes; Quinolones; Random Allocation; Swine | 2002 |
Pharmacokinetics and endometrial tissue concentrations of enrofloxacin and the metabolite ciprofloxacin after i.v. administration of enrofloxacin to mares.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Chromatography, High Pressure Liquid; Ciprofloxacin; Endometrium; Enrofloxacin; Female; Fluoroquinolones; Horses; Infusions, Intravenous; Quinolones | 2002 |
Antimicrobial activity of a novel des-fluoro (6) quinolone, garenoxacin (BMS-284756), compared to other quinolones, against clinical isolates from cancer patients.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Female; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Indoles; Levofloxacin; Male; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Sensitivity and Specificity | 2002 |
Comparative pharmacokinetics of enrofloxacin and tissue concentrations of parent drug and ciprofloxacin after intramuscular administrations of free and liposome-encapsulated enrofloxacin in rabbits.
Topics: Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Carriers; Enrofloxacin; Fluoroquinolones; Injections, Intramuscular; Liposomes; Quinolones; Rabbits; Tissue Distribution | 2002 |
In vivo selection of Campylobacter isolates with high levels of fluoroquinolone resistance associated with gyrA mutations and the function of the CmeABC efflux pump.
Topics: Animals; Anti-Infective Agents; Campylobacter Infections; Campylobacter jejuni; Chickens; Ciprofloxacin; DNA Gyrase; Drug Resistance, Microbial; Enrofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Quinolones | 2003 |
Plasma concentrations of enrofloxacin and its active metabolite ciprofloxacin in dogs following single oral administration of enrofloxacin at 7.5, 10, or 20 mg/kg.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Dogs; Dose-Response Relationship, Drug; Enrofloxacin; Female; Fluoroquinolones; Quinolones | 2002 |
[Synthesis and antibacterial activity of 5-amino-6, 8-difluoro-1-(5-fluoro-2-pyridyl)-7-(3-methyl-1-piperazinyl)-1, 4-dihydro-4-oxo-3-quinolinecarboxylic acid and its analogues].
Topics: Anti-Infective Agents; Ciprofloxacin; Escherichia coli; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Pyridines; Quinolones; Staphylococcus aureus | 2001 |
Mutant prevention concentration of garenoxacin (BMS-284756) for ciprofloxacin-susceptible or -resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Mutation; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcal Infections; Staphylococcus aureus | 2003 |
Determination of enrofloxacin and its metabolite ciprofloxacin in goat milk by high-performance liquid chromatography with diode-array detection. Optimization and validation.
Topics: Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Goats; Mass Spectrometry; Milk; Quinolones; Reproducibility of Results; Sensitivity and Specificity | 2003 |
[In vitro antibacterial activity of prulifloxacin, a new oral fluoroquinolone].
Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dosage Forms; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fleroxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Piperazines; Prodrugs; Quinolones | 2002 |
[In vitro short-term bactericidal activity and accumulation of NM394, the active metabolite of prulifloxacin, for Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa: comparison with ciprofloxacin, levofloxacin, and gatifloxacin].
Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Gatifloxacin; Levofloxacin; Ofloxacin; Piperazines; Prodrugs; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Time Factors | 2002 |
[Inhibitory activity of NM394, the active form of prodrug prulifloxacin against type II topoisomerase from Pseudomonas aeruginosa].
Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Fluoroquinolones; Gatifloxacin; Levofloxacin; Ofloxacin; Piperazines; Prodrugs; Pseudomonas aeruginosa; Quinolones; Topoisomerase II Inhibitors | 2002 |
Simulated in vitro quinolone pharmacodynamics at clinically achievable AUC/MIC ratios: advantage of I E over other integral parameters.
Topics: Anti-Bacterial Agents; Area Under Curve; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Gemifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Time Factors | 2002 |
Reliability of phototoxic tests of fluoroquinolones in vitro.
Topics: 3T3 Cells; Animals; Anti-Infective Agents; Ciprofloxacin; Cricetinae; Cricetulus; Dermatitis, Phototoxic; Female; Fluoroquinolones; Mice; Mice, Inbred BALB C; Micronucleus Tests; Norfloxacin; Quinolones; Rats; Rats, Wistar; Ultraviolet Rays | 2003 |
Pharmacokinetics of enrofloxacin and the rate of formation of its metabolite ciprofloxacin following intravenous and intramuscular single dose administration to male buffalo calves.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Buffaloes; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Half-Life; Injections, Intramuscular; Injections, Intravenous; Male; Quinolones | 2003 |
In vitro and in vivo activities of fluoroquinolones against Aeromonas hydrophila.
Topics: Aeromonas hydrophila; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Cefotaxime; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacterial Infections; Humans; In Vitro Techniques; Levofloxacin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Ofloxacin; Quinolines; Quinolones | 2003 |
Simultaneous measurement of fluoroquinolones in eggs by a combination of supercritical fluid extraction and high pressure liquid chromatography.
Topics: Anti-Bacterial Agents; Calibration; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Ciprofloxacin; Eggs; Enrofloxacin; Fluoroquinolones; Food Contamination; Norfloxacin; Ofloxacin; Quinolones; Solvents | 2003 |
[Studies on correlation between protonation and tautomerism and luminescence characteristics of quinolone].
Topics: Anti-Infective Agents; Chemical Phenomena; Chemistry, Physical; Ciprofloxacin; Energy Transfer; Fluoroquinolones; Hydrogen-Ion Concentration; Luminescence; Molecular Structure; Norfloxacin; Piperazines; Protons; Quinolones; Spectrometry, Fluorescence; Stereoisomerism; Structure-Activity Relationship | 2001 |
Binding characteristics of fluoroquinolones to synthetic levodopa melanin.
Topics: Binding Sites; Chloroquine; Ciprofloxacin; Drug Interactions; Enoxacin; Fluoroquinolones; Levodopa; Levofloxacin; Melanins; Monophenol Monooxygenase; Norfloxacin; Ofloxacin; Quinolones; Timolol | 2003 |
Chromosomally encoded gyrase inhibitor GyrI protects Escherichia coli against DNA-damaging agents.
Topics: Alkylating Agents; beta-Galactosidase; Ciprofloxacin; DNA Damage; DNA, Bacterial; DNA, Superhelical; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Genes, Reporter; Methylnitronitrosoguanidine; Mitomycin; Mutagenesis; Nalidixic Acid; Plasmids; Quinolones; Repressor Proteins; SOS Response, Genetics; Topoisomerase II Inhibitors; Ultraviolet Rays | 2003 |
In vitro antibacterial potency and spectrum of ABT-492, a new fluoroquinolone.
Topics: Animals; Anti-Bacterial Agents; Bacteria, Anaerobic; Blood Proteins; Ciprofloxacin; DNA Topoisomerases, Type II; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Protein Binding; Quinolones; Rats | 2003 |
Postantibiotic, postantibiotic sub-MIC, and subinhibitory effects of PGE-9509924, ciprofloxacin, and levofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Escherichia coli; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Streptococcus pneumoniae | 2003 |
Prulifloxacin: in vitro (HERG current) and in vivo (conscious dog) assessment of cardiac risk.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Aza Compounds; Cell Line; Ciprofloxacin; Dioxolanes; DNA-Binding Proteins; Dogs; Fluoroquinolones; In Vitro Techniques; Moxifloxacin; Patch-Clamp Techniques; Piperazines; Potassium Channel Blockers; Quinolines; Quinolones; Telemetry; Trans-Activators; Transcriptional Regulator ERG | 2003 |
Synthesis and in vitro antibacterial evaluation of N-[5-(5-nitro-2-thienyl)-1,3,4-thiadiazole-2-yl] piperazinyl quinolones.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Enoxacin; Microbial Sensitivity Tests; Norfloxacin; Piperazine; Piperazines; Quinolones | 2003 |
Novel oxazolidinone-quinolone hybrid antimicrobials.
Topics: Acetamides; Anti-Bacterial Agents; Ciprofloxacin; DNA Topoisomerase IV; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Quinolones; Structure-Activity Relationship | 2003 |
In vivo efficacy of a new quinolone, DQ-113, against Streptococcus pneumoniae in a mouse model.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Lung; Male; Mice; Mice, Inbred CBA; Microbial Sensitivity Tests; Penicillin Resistance; Pneumonia, Pneumococcal; Quinolones; Survival Analysis | 2003 |
Incidence of quinolone resistance in strains of Salmonella isolated from poultry, cattle and pigs in Germany between 1998 and 2001.
Topics: Amino Acid Sequence; Animals; Anti-Infective Agents; Cattle; Ciprofloxacin; Colony Count, Microbial; DNA, Bacterial; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Incidence; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Poultry; Quinolones; Salmonella; Salmonella Infections, Animal; Serotyping; Swine | 2003 |
Effect of a 5 day enrofloxacin treatment on Salmonella enterica serotype Typhimurium DT104 in the pig.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Colony Count, Microbial; Cyclohexanes; DNA Gyrase; Drug Resistance, Bacterial; Enrofloxacin; Feces; Fluoroquinolones; Genes, Bacterial; Microbial Sensitivity Tests; Nalidixic Acid; Phenotype; Quinolones; Salmonella enterica; Salmonella Infections; Swine | 2004 |
[Analysis of the response factors of different quinolones detected by evaporative light-scattering detector].
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Light; Linear Models; Ofloxacin; Quinolones | 2003 |
Corneal and scleral permeability of quinolones--a pharmacokinetics study.
Topics: Administration, Topical; Animals; Aqueous Humor; Cell Membrane Permeability; Cinoxacin; Ciprofloxacin; Conjunctiva; Cornea; Enoxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones; Rabbits; Sclera; Time Factors; Water | 2003 |
Compare two methods of measuring DNA damage induced by photogenotoxicity of fluoroquinolones.
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Comet Assay; Cricetinae; Cricetulus; DNA; DNA Damage; Fibroblasts; Fluoroquinolones; Levofloxacin; Ofloxacin; Quinolones; Ultraviolet Rays | 2004 |
Pharmacokinetics of enrofloxacin in neonatal kittens.
Topics: Administration, Oral; Age Factors; Animals; Cats; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Injections, Subcutaneous; Quinolones; Time Factors | 2004 |
Emergence of fluoroquinolone resistance in the native Campylobacter coli population of pigs exposed to enrofloxacin.
Topics: Animals; Anti-Infective Agents; Campylobacter coli; Chromatography, High Pressure Liquid; Ciprofloxacin; DNA Gyrase; DNA, Bacterial; Drug Resistance, Bacterial; Enrofloxacin; Feces; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones; Swine | 2004 |
Simple, rapid determination of enrofloxacin and ciprofloxacin in bovine milk and plasma by high-performance liquid chromatography with fluorescence detection.
Topics: Animals; Calibration; Cattle; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Milk; Molecular Structure; Quinolones; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2004 |
Atomic absorption spectroscopic, conductometric and colorimetric methods for determination of fluoroquinolone antibiotics using ammonium reineckate ion-pair complex formation.
Topics: Absorption; Acetone; Anti-Bacterial Agents; Ciprofloxacin; Colorimetry; Dose-Response Relationship, Drug; Electric Conductivity; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Ions; Linear Models; Norfloxacin; Ofloxacin; Quaternary Ammonium Compounds; Quinolones; Salts; Solvents; Spectrophotometry, Atomic; Thiocyanates | 2004 |
Comparative study of the in vitro activity of a new fluoroquinolone, ABT-492.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Bacterial Infections; Chlamydia trachomatis; Chlamydophila pneumoniae; Ciprofloxacin; Erythromycin; Fluoroquinolones; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Quinolones | 2004 |
A reverse-phase HPLC assay for the simultaneous determination of enrofloxacin and ciprofloxacin in pig faeces.
Topics: Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Feces; Fluoroquinolones; Quinolones; Reproducibility of Results; Sensitivity and Specificity; Swine | 2004 |
Increasing incidence of quinolone-resistant E. coli from urinary cultures in Ankara-Pursaklar region.
Topics: Adolescent; Anti-Infective Agents; Child; Child, Preschool; Ciprofloxacin; Culture Media; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Infections; Humans; Quinolones; Turkey; Urinary Tract Infections; Urine | 2004 |
Inhibition of human immunodeficiency virus type 1 tat-trans-activation-responsive region interaction by an antiviral quinolone derivative.
Topics: Amino Acid Sequence; Anti-HIV Agents; Ciprofloxacin; DNA, Viral; Gene Products, tat; HIV Long Terminal Repeat; HIV-1; Isoquinolines; Molecular Sequence Data; Mutation; Plasmids; Pyrroles; Quinolones; RNA, Viral; tat Gene Products, Human Immunodeficiency Virus | 2004 |
Characterization of the molecular mechanisms of quinolone resistance in Yersinia enterocolitica O:3 clinical isolates.
Topics: Anti-Infective Agents; Ciprofloxacin; Dipeptides; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Quinolones; Spain; Yersinia enterocolitica; Yersinia Infections | 2004 |
Influence of enrofloxacin administration and alpha-tocopheryl acetate supplemented diets on oxidative stability of broiler tissues.
Topics: alpha-Tocopherol; Animals; Anti-Infective Agents; Antioxidants; Catalase; Chickens; Ciprofloxacin; Diet; Dietary Supplements; Drug Residues; Enrofloxacin; Female; Fluoroquinolones; Glutathione Peroxidase; Iron; Lipid Peroxidation; Liver; Meat; Muscle, Skeletal; Oxidation-Reduction; Quinolones; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tocopherols; Vitamin E | 2004 |
[Study on the gene mutation of quinolone-resistant Mycobacterium tuberculosis isolated from Sichuan Province].
Topics: Antibiotics, Antitubercular; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Mutation; Mycobacterium tuberculosis; Ofloxacin; Polymorphism, Single-Stranded Conformational; Quinolones | 2004 |
Allometric analysis of ciprofloxacin and enrofloxacin pharmacokinetics across species.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Humans; Models, Biological; Quinolones; Species Specificity; Veterinary Drugs | 2004 |
Detection of enrofloxacin and its metabolite ciprofloxacin in equine hair.
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Female; Fluoroquinolones; Hair; Hair Color; Horses; Injections, Intravenous; Longitudinal Studies; Male; Melanins; Quinolones; Trifluoroacetic Acid | 2004 |
[Study on the molecular mechanism of quinolone resistance in Shigellae spp].
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pipemidic Acid; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Quinolones; Shigella | 2004 |
Single-nucleotide polymorphism mutation spectra and resistance to quinolones in Salmonella enterica serovar Enteritidis with a mutator phenotype.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Base Pair Mismatch; Chloramphenicol; Ciprofloxacin; DNA Gyrase; DNA Primers; DNA Probes; DNA Repair; DNA Topoisomerase IV; Drug Resistance, Bacterial; Enrofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Phenotype; Polymorphism, Single Nucleotide; Quinolones; Salmonella enterica; Salmonella Infections | 2004 |
Mutant prevention concentrations of ciprofloxacin and enrofloxacin for Salmonella enterica.
Topics: Anti-Infective Agents; Ciprofloxacin; Cyclohexanes; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Enrofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Quinolones; Salmonella enterica; Salmonella enteritidis; Salmonella typhimurium | 2004 |
[A study on the active efflux mechanism in Staphylococcus aureus resistant to quinolone].
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Quinolones; Reserpine; Staphylococcus aureus | 2004 |
Comparative pharmacodynamics of the new fluoroquinolone ABT492 and ciprofloxacin with Escherichia coli and Pseudomonas aeruginosa in an in vitro dynamic model.
Topics: Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Half-Life; Humans; Microbial Sensitivity Tests; Models, Biological; Pseudomonas aeruginosa; Quinolones | 2004 |
Oral quinolones in hospitalized patients: an evaluation of a computerized decision support intervention.
Topics: Administration, Oral; Ciprofloxacin; Costs and Cost Analysis; Decision Support Systems, Clinical; Fluoroquinolones; Hospital Units; Hospitalization; Humans; Injections, Intravenous; Ofloxacin; Prospective Studies; Quinolones | 2004 |
Increasing prevalence of quinolone resistance in human nontyphoid Salmonella enterica isolates obtained in Spain from 1981 to 2003.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; Feces; Food Microbiology; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Salmonella enterica; Salmonella Infections; Salmonella typhimurium; Spain | 2004 |
Long depletion time of enrofloxacin in rainbow trout (Oncorhynchus mykiss).
Topics: Animals; Anti-Bacterial Agents; Bone and Bones; Chromatography, High Pressure Liquid; Ciprofloxacin; Diet; Enrofloxacin; Fluoroquinolones; Muscle, Skeletal; Oncorhynchus mykiss; Quinolones; Reproducibility of Results | 2004 |
Prevalence of mutations within the quinolone resistance-determining region of gyrA, gyrB, parC, and parE and association with antibiotic resistance in quinolone-resistant Salmonella enterica.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Codon; DNA Gyrase; DNA Primers; DNA Topoisomerase IV; DNA Topoisomerases, Type I; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Microbial Sensitivity Tests; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Salmonella enterica | 2004 |
Determination of enrofloxacin and its primary metabolite, ciprofloxacin, in pig tissues. Application to residue studies.
Topics: Adipose Tissue; Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Residues; Enrofloxacin; Fluoroquinolones; Kidney; Liver; Male; Muscles; Quinolones; Reference Standards; Reproducibility of Results; Sus scrofa | 2005 |
Synthesis and comparison of 99mTc-enrofloxacin and 99mTc-ciprofloxacin.
Topics: Animals; Candida albicans; Candidiasis; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Organotechnetium Compounds; Quinolones; Radionuclide Imaging; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Technetium; Thigh | 2004 |
Interaction of the plasmid-encoded quinolone resistance protein Qnr with Escherichia coli DNA gyrase.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Plasmids; Quinolones; Recombinant Fusion Proteins | 2005 |
Susceptibility of Campylobacter hyointestinalis subsp. hyointestinalis to antimicrobial agents and characterization of quinolone-resistant strains.
Topics: Animals; Campylobacter hyointestinalis; Cattle; Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalidixic Acid; Quinolones; Reindeer | 2005 |
[Simultaneous determination of quinolones in foods by LC/MS/MS].
Topics: Animals; Chromatography, Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fishes; Fluoroquinolones; Food Analysis; Meat; Ofloxacin; Quinolones; Spectrometry, Mass, Electrospray Ionization | 2004 |
Antibacterial studies, DNA oxidative cleavage, and crystal structures of Cu(II) and Co(II) complexes with two quinolone family members, ciprofloxacin and enoxacin.
Topics: Anti-Infective Agents; Cations; Ciprofloxacin; Cobalt; Copper; Crystallography, X-Ray; DNA; Electrophoresis, Agar Gel; Enoxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Ligands; Molecular Structure; Organometallic Compounds; Oxidation-Reduction; Quinolones | 2005 |
Comparison of pharmacokinetics of danofloxacin and enrofloxacin in calves challenged with Mannheimia haemolytica.
Topics: Animals; Anti-Infective Agents; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Cattle; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Lung; Male; Mannheimia haemolytica; Microbial Sensitivity Tests; Pasteurellosis, Pneumonic; Quinolones | 2005 |
Pharmacokinetics of enrofloxacin following intravenous administration to greater rheas: a preliminary study.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Half-Life; Injections, Intravenous; Quinolones; Rheiformes | 2005 |
Vibrational spectroscopic characterization of fluoroquinolones.
Topics: Aza Compounds; Cinoxacin; Ciprofloxacin; DNA Gyrase; DNA, Bacterial; Enoxacin; Enzyme Inhibitors; Fluoroquinolones; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Chemical; Models, Molecular; Models, Theoretical; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxolinic Acid; Quinolines; Quinolones; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Temperature; Ultraviolet Rays; Vibration; Water | 2005 |
Study of enrofloxacin depletion in the eggs of laying hens using diphasic dialysis extraction/purification and determinative HPLC-MS analysis.
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Dialysis; Drug Residues; Eggs; Enrofloxacin; Female; Fluoroquinolones; Kinetics; Mass Spectrometry; Quinolones | 2005 |
Comparative pharmacodynamics of the new fluoroquinolone ABT492 and levofloxacin with Streptococcus pneumoniae in an in vitro dynamic model.
Topics: Anti-Bacterial Agents; Area Under Curve; Ciprofloxacin; Computer Simulation; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Streptococcus pneumoniae; Time Factors | 2005 |
Dual targeting of topoisomerase IV and gyrase to reduce mutant selection: direct testing of the paradigm by using WCK-1734, a new fluoroquinolone, and ciprofloxacin.
Topics: Alleles; Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; Cloning, Molecular; DNA Gyrase; DNA Primers; DNA Topoisomerase IV; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Plasmids; Quinolones; Staphylococcus aureus | 2005 |
Influence of efflux transporters on the accumulation and efflux of four quinolones (ciprofloxacin, levofloxacin, garenoxacin, and moxifloxacin) in J774 macrophages.
Topics: Anti-Infective Agents; Aza Compounds; Cell Line; Ciprofloxacin; Fluoroquinolones; Heat-Shock Response; Humans; Kinetics; Levofloxacin; Macrophages; Moxifloxacin; Ofloxacin; Quinolines; Quinolones | 2005 |
In vitro activity of fluoroquinolones against Mycobacterium tuberculosis.
Topics: Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Quinolones; Sampling Studies; Sensitivity and Specificity | 2005 |
Re: synthesis and comparison of 99mTc-enrofloxacin and 99mTc-ciprofloxacin.
Topics: Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Organotechnetium Compounds; Quinolones; Radiopharmaceuticals; Terminology as Topic | 2005 |
The simultaneous separation and determination of five quinolone antibiotics using isocratic reversed-phase HPLC: application to stability studies on an ofloxacin tablet formulation.
Topics: Anti-Bacterial Agents; Calibration; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Industry; Drug Stability; Fluoroquinolones; Hydrogen-Ion Concentration; Models, Chemical; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones; Reproducibility of Results; Tablets; Time Factors | 2005 |
Inhibition of cell differentiation by quinolones in micromass cultures of rat embryonic limb bud and midbrain cells.
Topics: Animals; Anti-Infective Agents; Cell Differentiation; Cell Proliferation; Cell Survival; Ciprofloxacin; Dose-Response Relationship, Drug; Embryo Culture Techniques; Enrofloxacin; Fluoroquinolones; Inhibitory Concentration 50; Limb Buds; Mesencephalon; Norfloxacin; Quinolones; Rats; Rats, Wistar | 2005 |
Microbiological rationale for the utilisation of prulifloxacin, a new fluoroquinolone, in the eradication of serious infections caused by Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Cystic Fibrosis; Dioxolanes; Drug Resistance, Bacterial; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Opportunistic Infections; Piperazines; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolines; Quinolones | 2005 |
New quinolone resistance phenomenon in Salmonella enterica: nalidixic acid-susceptible isolates with reduced fluoroquinolone susceptibility.
Topics: Anti-Infective Agents; Asia; Ciprofloxacin; Drug Resistance, Bacterial; Feces; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Nalidixic Acid; Quinolones; Salmonella enterica; Salmonella Infections; Travel | 2005 |
Synergistic effect of fosfomycin and fluoroquinolones against Pseudomonas aeruginosa growing in a biofilm.
Topics: Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Drug Synergism; Fluoroquinolones; Fosfomycin; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Pseudomonas aeruginosa; Quinolones | 2005 |
DX-619, a novel des-fluoro(6) quinolone manifesting low frequency of selection of resistant Staphylococcus aureus mutants: quinolone resistance beyond modification of type II topoisomerases.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Topoisomerases, Type II; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Microbial Sensitivity Tests; Mutation; Naphthyridines; Pyrrolidines; Quinolones; Staphylococcus aureus; Topoisomerase II Inhibitors | 2005 |
Interactions between 4-quinolone antibacterials and multivalent metal ions.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Gram-Negative Bacteria; Metals; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones | 1989 |
Characterization of a cmeABC operon in a quinolone-resistant Campylobacter coli isolate of Irish origin.
Topics: Anti-Bacterial Agents; Campylobacter coli; Campylobacter jejuni; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ireland; Multidrug Resistance-Associated Proteins; Nalidixic Acid; Operon; Quinolones | 2005 |
T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antigen-Presenting Cells; Aza Compounds; Cell Proliferation; Cells, Cultured; Ciprofloxacin; Clone Cells; Cross Reactions; Drug Hypersensitivity; Enoxacin; Female; Fluoroquinolones; Humans; Hypersensitivity, Delayed; Middle Aged; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Patch Tests; Pipemidic Acid; Quinolines; Quinolones; T-Lymphocytes | 2006 |
Genetic characterization and antibiotic resistance of Campylobacter spp. isolated from poultry and humans in Senegal.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; Campylobacter; Campylobacter coli; Campylobacter jejuni; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Erythromycin; Food Microbiology; Genes, Bacterial; Genetic Variation; Genotype; Humans; Nalidixic Acid; Poultry; Quinolones | 2006 |
Synthesis and antibacterial activity of N-[2-[5-(methylthio)thiophen-2-yl]-2-oxoethyl] and N-[2-[5-(methylthio)thiophen-2-yl]-2-(oxyimino)ethyl]piperazinylquinolone derivatives.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Microbial Sensitivity Tests; Molecular Structure; Piperazines; Quinolones; Staphylococcus; Thiophenes | 2006 |
Selective action of fluoroquinolones against intracellular amastigotes of Leishmania (Viannia) panamensis in vitro.
Topics: Animals; Cell Line; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Leishmania guyanensis; Macrophages; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones | 2005 |
Transfection of drug-specific T-cell receptors into hybridoma cells: tools to monitor drug interaction with T-cell receptors and evaluate cross-reactivity to related compounds.
Topics: Animals; B-Lymphocytes; CD3 Complex; CD4 Antigens; Cell Line, Transformed; Cells, Cultured; Ciprofloxacin; Cross Reactions; Drug Interactions; Flow Cytometry; Humans; Hybridomas; Interleukin-2; Mice; Norfloxacin; Quinolones; Receptors, Antigen, T-Cell; Sulfamethizole; Sulfamethoxazole; Sulfanilamides; T-Lymphocytes; Time Factors; Transfection | 2006 |
Functional analysis of spoT, relA and dksA genes on quinolone tolerance in Pseudomonas aeruginosa under nongrowing condition.
Topics: Ciprofloxacin; Drug Resistance; Guanosine Tetraphosphate; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quinolones | 2006 |
Comparative in vitro activity of PGE 9262932 and fluoroquinolones against Canadian clinical Streptococcus pneumoniae isolates, including molecularly characterized ciprofloxacin-resistant isolates.
Topics: Anti-Bacterial Agents; Canada; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Genotype; Humans; Microbial Sensitivity Tests; Mutation; Pneumococcal Infections; Quinolones; Streptococcus pneumoniae | 2006 |
Cellular accumulation and activity of quinolones in ciprofloxacin-resistant J774 macrophages.
Topics: Animals; Anti-Infective Agents; Cell Line; Ciprofloxacin; Clone Cells; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Macrophages; Mice; Quinolones | 2006 |
Genetic diversity and quinolone resistance in Campylobacter jejuni isolates from poultry in Senegal.
Topics: Animals; Anti-Infective Agents; Campylobacter jejuni; Chickens; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Genetic Variation; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Poultry; Quinolones; Senegal | 2006 |
Identification of the plasmid-borne quinolone resistance gene qnrS in Salmonella enterica serovar Infantis.
Topics: Ampicillin; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Evolution, Molecular; Genes, Bacterial; Nalidixic Acid; Plasmids; Quinolones; Salmonella enterica | 2006 |
Differential effects of levofloxacin and ciprofloxacin on the risk for isolation of quinolone-resistant Pseudomonas aeruginosa.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Case-Control Studies; Ciprofloxacin; Cross Infection; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Levofloxacin; Male; Middle Aged; Ofloxacin; Pseudomonas Infections; Quinolones; Regression Analysis; Retrospective Studies; Risk Factors | 2006 |
In vitro activities of DX-619 and comparison quinolones against gram-positive cocci.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Enterococcus; Fluoroquinolones; Gatifloxacin; Gram-Positive Cocci; In Vitro Techniques; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Pyrrolidines; Quinolines; Quinolones; Staphylococcus aureus; Streptococcus pneumoniae; Streptococcus pyogenes | 2006 |
Quinolones sensitize gram-negative bacteria to antimicrobial peptides.
Topics: Anti-Infective Agents; Antimicrobial Cationic Peptides; Cell Membrane Permeability; Ciprofloxacin; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 2006 |
Photo-chemically induced DNA effects in the comet assay with epidermal cells of SKH-1 mice after a single oral administration of different fluoroquinolones and 8-methoxypsoralen in combination with exposure to UVA.
Topics: Administration, Oral; Animals; Cells, Cultured; Ciprofloxacin; Comet Assay; DNA; DNA Damage; Epidermal Cells; Epidermis; Fluoroquinolones; Male; Methoxsalen; Mice; Mice, Hairless; Quinolones; Ultraviolet Rays | 2006 |
Antimicrobial susceptibility and molecular determinants of quinolone resistance in Neisseria gonorrhoeae isolates from Shanghai.
Topics: Anti-Infective Agents; China; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Humans; Male; Microbial Sensitivity Tests; Mutation; Neisseria gonorrhoeae; Quinolones | 2006 |
Quinolones for brucellosis: treating old diseases with new drugs.
Topics: Anti-Infective Agents; Brucella; Brucellosis; Ciprofloxacin; Drug Resistance, Bacterial; Humans; Quinolones; Treatment Outcome | 2006 |
Quinolone resistance determinant qnrA3 in clinical isolates of Salmonella in 2000-2005 in Hong Kong.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; Genes, Bacterial; Hong Kong; Humans; Microbial Sensitivity Tests; Quinolones; Salmonella; Salmonella Infections | 2006 |
Enrofloxacin and marbofloxacin in horses: comparison of pharmacokinetic parameters, use of urinary and metabolite data to estimate first-pass effect and absorbed fraction.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Area Under Curve; Biological Availability; Ciprofloxacin; Enrofloxacin; Enzyme Inhibitors; Female; Fluoroquinolones; Half-Life; Horses; Injections, Intravenous; Quinolones | 2006 |
Quinolone resistance in Helicobacter pylori isolates in Germany.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Germany; Helicobacter Infections; Helicobacter pylori; Humans; Microbial Sensitivity Tests; Quinolones | 2007 |
Effect of anaerobic growth on quinolone lethality with Escherichia coli.
Topics: Aerobiosis; Anaerobiosis; Anti-Infective Agents; Chloramphenicol; Ciprofloxacin; DNA Fragmentation; DNA Gyrase; DNA, Bacterial; DnaB Helicases; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Escherichia coli; Microbial Sensitivity Tests; Models, Biological; Molecular Structure; Nalidixic Acid; Quinolones | 2007 |
Determination of a series of quinolones in pig plasma using solid-phase extraction and liquid chromatography coupled with mass spectrometric detection Application to pharmacokinetic studies.
Topics: Animals; Chromatography, Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Quinolones; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Swine | 2006 |
In vitro development of resistance to DX-619 and other quinolones in enterococci.
Topics: Anti-Bacterial Agents; Aza Compounds; Bacterial Proteins; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Enterococcus faecalis; Enterococcus faecium; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Polymerase Chain Reaction; Pyrrolidines; Quinolines; Quinolones; Sequence Analysis, DNA | 2006 |
Investigations of the antibacterial properties of ciprofloxacin@SiO2.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Escherichia coli; Fluorescein-5-isothiocyanate; Kinetics; Lactococcus lactis; Microscopy, Electron, Transmission; Nanoparticles; Octanols; Quinolones; Silicon Dioxide; Ultraviolet Rays; Water | 2006 |
Assessment of enrofloxacin and ciprofloxacin accumulation in pig and calf hair by HPLC and fluorimetric detection.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluorometry; Fluoroquinolones; Hair; Liver; Molecular Structure; Muscles; Quinolones; Swine | 2007 |
Campylobacter coli isolates derived from chickens in Senegal: Diversity, genetic exchange with Campylobacter jejuni and quinolone resistance.
Topics: Alleles; Animals; Anti-Infective Agents; Campylobacter coli; Campylobacter jejuni; Chickens; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Genetic Variation; Nalidixic Acid; Polymerase Chain Reaction; Quinolones; Senegal | 2007 |
Synthesis and antibacterial activity of 4,5,6,7-tetrahydro-thieno[3,2-c]pyridine quinolones.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Chemistry, Pharmaceutical; Ciprofloxacin; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Microbial Sensitivity Tests; Models, Chemical; Molecular Conformation; Pyridines; Quinolones | 2007 |
In vitro activity of prulifloxacin against Escherichia coli isolated from urinary tract infections and the biological cost of prulifloxacin resistance.
Topics: Anti-Infective Agents, Urinary; Bacterial Adhesion; Ciprofloxacin; Dioxolanes; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Hemolysin Proteins; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones; Ultraviolet Rays; Urinary Tract Infections | 2007 |
Proarrhythmia as a class effect of quinolones: increased dispersion of repolarization and triangulation of action potential predict torsades de pointes.
Topics: Action Potentials; Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiologic Techniques, Cardiac; Fluoroquinolones; Heart Conduction System; In Vitro Techniques; Levofloxacin; Male; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Rabbits; Torsades de Pointes | 2007 |
[In vitro activity of prulifloxacin, levofloxacin and ciprofloxacin against urinary pathogens].
Topics: Anti-Bacterial Agents; Ciprofloxacin; Dioxolanes; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; In Vitro Techniques; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones; Staphylococcus aureus; Urinary Tract Infections | 2006 |
Synthesis and evaluation of new arylbenzo[b]thiophene and diarylthiophene derivatives as inhibitors of the NorA multidrug transporter of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bacterial Proteins; Cell Line, Tumor; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Drug Screening Assays, Antitumor; Ethidium; Humans; Indicators and Reagents; Macrolides; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Quinolones; Staphylococcus aureus; Structure-Activity Relationship; Thiophenes | 2007 |
Experimental electron density study of a complex between copper(II) and the antibacterial quinolone family member ciprofloxacin.
Topics: Algorithms; Anti-Bacterial Agents; Ciprofloxacin; Copper; Crystallography, X-Ray; Electrons; Hydrogen Bonding; Models, Molecular; Molecular Structure; Organometallic Compounds; Quinolones; Static Electricity | 2007 |
Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1.
Topics: Anti-Infective Agents; Base Sequence; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae; Gene Expression Regulation, Bacterial; Genes, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid | 2007 |
Allometric scaling of marbofloxacin, moxifloxacin, danofloxacin and difloxacin pharmacokinetics: a retrospective analysis.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Humans; Moxifloxacin; Quinolines; Quinolones; Retrospective Studies; Species Specificity | 2007 |
Emergence of the quinolone resistance-mediating gene aac(6')-Ib-cr in extended-spectrum-beta-lactamase-producing Klebsiella isolates collected in Slovenia between 2000 and 2005.
Topics: beta-Lactamases; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacteriaceae Infections; Humans; Klebsiella; Microbial Sensitivity Tests; Plasmids; Quinolones; Slovenia | 2007 |
[Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry].
Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2007 |
Organic anion transporter 3 (oat3/slc22a8) interacts with carboxyfluoroquinolones, and deletion increases systemic exposure to ciprofloxacin.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Biological Transport; CHO Cells; Ciprofloxacin; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Female; Gene Deletion; Male; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Mice, Knockout; Microinjections; Oocytes; Organic Anion Transporters, Sodium-Independent; Quinolones; Xenopus laevis | 2008 |
Presence of qnr gene in Escherichia coli and Klebsiella pneumoniae resistant to ciprofloxacin isolated from pediatric patients in China.
Topics: Anti-Infective Agents; Bacterial Proteins; Child; Child, Preschool; China; Ciprofloxacin; DNA Primers; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Hospitals, Pediatric; Humans; Klebsiella pneumoniae; Polymerase Chain Reaction; Quinolones | 2008 |
Prevalence of quinolone resistance mechanisms and associations to minimum inhibitory concentrations in quinolone-resistant Escherichia coli isolated from humans and swine in Denmark.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Denmark; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Humans; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Prevalence; Quinolones; Swine; Swine Diseases | 2008 |
Alteration of GyrA amino acid required for ciprofloxacin resistance in Klebsiella pneumoniae isolates in China.
Topics: Amino Acid Substitution; Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Quinolones | 2008 |
Plasmid-mediated QnrS2 determinant from a clinical Aeromonas veronii isolate.
Topics: Aeromonas; Ciprofloxacin; Drug Resistance, Bacterial; Genes, Bacterial; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Plasmids; Quinolones | 2008 |
Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates.
Topics: Anti-Infective Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Ciprofloxacin; Drug Resistance, Bacterial; Enterobacter cloacae; Genes, Bacterial; Microbial Sensitivity Tests; Plasmids; Quinolones | 2008 |
Effect of a program to reduce hospital ciprofloxacin use on nosocomial Pseudomonas aeruginosa susceptibility to quinolones and other antimicrobial agents.
Topics: Anti-Infective Agents; Ciprofloxacin; Cross Infection; Drug Resistance, Bacterial; Hospital Bed Capacity, 500 and over; Hospitals, Teaching; Humans; Incidence; Microbial Sensitivity Tests; Program Evaluation; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones | 2008 |
Investigation of plasmid-mediated quinolone resistance among isolates obtained in a Turkish intensive care unit.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Intensive Care Units; Microbial Sensitivity Tests; Plasmids; Prevalence; Quinolones; Turkey | 2008 |
Study of fluorescence characteristics of the charge-transfer reaction of quinolone agents with bromanil.
Topics: Anti-Bacterial Agents; Benzoquinones; Catalysis; Ciprofloxacin; Electrons; Energy Transfer; Models, Biological; Norfloxacin; Ofloxacin; Osmolar Concentration; Quinolones; Solvents; Spectrometry, Fluorescence; Technology, Pharmaceutical; Temperature; Time Factors | 2009 |
High rates of plasmid-mediated quinolone resistance QnrB variants among ciprofloxacin-resistant Escherichia coli and Klebsiella pneumoniae from urinary tract infections in Korea.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Genes, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Korea; Microbial Sensitivity Tests; Plasmids; Quinolones; Urinary Tract Infections | 2008 |
Risk factors of ciprofloxacin resistance in urinary Escherichia coli isolates.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Case-Control Studies; Chi-Square Distribution; Ciprofloxacin; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Multivariate Analysis; Quinolones; Risk Factors; Taiwan; Urinary Catheterization; Urinary Tract Infections | 2008 |
Biofilm formation is not necessary for development of quinolone-resistant "persister" cells in an attached Staphylococcus epidermidis population.
Topics: Anti-Infective Agents; Aza Compounds; Bacterial Adhesion; Biofilms; Ciprofloxacin; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Naphthyridines; Prosthesis-Related Infections; Quinolines; Quinolones; Staphylococcal Infections; Staphylococcus epidermidis | 2008 |
grlA and gyrA mutations and antimicrobial susceptibility in clinical isolates of ciprofloxacin- methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Electrophoresis, Agar Gel; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Gatifloxacin; Gene Expression Regulation, Bacterial; Methicillin Resistance; Mutation; Polymerase Chain Reaction; Quinolones; Staphylococcus aureus; Trans-Activators | 2008 |
Determination of quinolone antibiotics in urine by capillary electrophoresis with chemiluminescence detection.
Topics: Anti-Infective Agents; Ciprofloxacin; Electrophoresis, Capillary; Humans; Luminescent Measurements; Molecular Structure; Norfloxacin; Ofloxacin; Quinolones; Sensitivity and Specificity; Solvents | 2008 |
Simple assay for monitoring seven quinolone antibacterials in eggs: extraction with hot water and liquid chromatography coupled to tandem mass spectrometry. Laboratory validation in line with the European Union Commission Decision 657/2002/EC.
Topics: Animals; Anti-Bacterial Agents; Calibration; Chickens; Chromatography, Liquid; Ciprofloxacin; Drug Residues; Eggs; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Linear Models; Quinolones; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Temperature | 2009 |
Comparison of in vitro susceptibilities of Gram-positive cocci isolated from ocular infections against the second and fourth generation quinolones at a tertiary eye care centre in South India.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Eye Infections, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacterial Infections; Humans; India; Male; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Retrospective Studies; Staphylococcus; Streptococcus | 2010 |
First report of plasmid-mediated quinolone resistance determinant qnrS1 in an Escherichia coli strain of animal origin in Italy.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Microbial Sensitivity Tests; Plasmids; Poultry; Poultry Diseases; Quinolones; Salmonella enterica | 2009 |
Quantitation and identity confirmation of residues of quinolones in tilapia fillets by LC-ESI-MS-MS QToF.
Topics: Animals; Chromatography, Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Food Analysis; Oxolinic Acid; Quinolones; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tilapia | 2009 |
Probing the differential interactions of quinazolinedione PD 0305970 and quinolones with gyrase and topoisomerase IV.
Topics: Ciprofloxacin; DNA Topoisomerase IV; Molecular Structure; Mutation; Polymerase Chain Reaction; Pyrrolidines; Quinazolinones; Quinolones; Sequence Analysis, DNA; Streptococcus pneumoniae; Topoisomerase II Inhibitors | 2009 |
[Multi-residue determination of 11 quinolones in chicken muscle by high performance liquid chromatography with fluorescence detection].
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Residues; Fluorescence; Norfloxacin; Ofloxacin; Poultry Products; Quinolones | 2009 |
Plasmid-mediated quinolone resistance in Salmonella isolated from patients with overseas travelers' diarrhea in Japan.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Diarrhea; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Japan; Microbial Sensitivity Tests; Nalidixic Acid; Plasmids; Quinolones; Salmonella; Salmonella Infections; Travel | 2009 |
Validation of a MLC method with fluorescence detection for the determination of quinolones in urine samples by direct injection.
Topics: Anti-Bacterial Agents; Aza Compounds; Calibration; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluorescence; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Reproducibility of Results | 2009 |
Transferable quinolone resistance in Vibrio cholerae.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Chromosomes, Bacterial; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Transposable Elements; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Polymerase Chain Reaction; Quinolones; Vibrio cholerae | 2010 |
Bartonella bacilliformis, endemic pathogen of the Andean region, is intrinsically resistant to quinolones.
Topics: Anti-Bacterial Agents; Bartonella bacilliformis; Bartonella Infections; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Epidemiology; Nalidixic Acid; Quinolones; Sequence Analysis, Protein; Spain | 2010 |
Association of ciprofloxacin prescriptions to outpatients to Clostridium difficile infections.
Topics: Anti-Infective Agents; Ciprofloxacin; Clostridioides difficile; Clostridium Infections; Contraindications; Germany; Humans; Outpatients; Quinolones | 2010 |
Ciprofloxacin-sensitive and ciprofloxacin-resistant Campylobacter jejuni are equally susceptible to natural orange oil-based antimicrobials.
Topics: Animals; Anti-Infective Agents; Campylobacter jejuni; Chromatography, Gas; Ciprofloxacin; Cyclohexenes; Drug Resistance, Bacterial; Limonene; Mass Spectrometry; Microbial Sensitivity Tests; Plant Oils; Polymerase Chain Reaction; Quinolones; Terpenes | 2009 |
Improving quinolone use in hospitals by using a bundle of interventions in an interrupted time series analysis.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Hospitals; Humans; Injections, Intravenous; Prospective Studies; Quinolones | 2010 |
Rapidly spreading CTX-M-type beta-lactamase-producing Proteus mirabilis in Japan.
Topics: Anti-Bacterial Agents; Bacterial Typing Techniques; beta-Lactamases; beta-Lactams; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Japan; Microbial Sensitivity Tests; Molecular Epidemiology; Polymerase Chain Reaction; Prevalence; Proteus Infections; Proteus mirabilis; Quinolones; Sequence Analysis, DNA; Time Factors | 2010 |
In vitro activity of nemonoxacin, tigecycline, and other antimicrobial agents against Helicobacter pylori isolates in Taiwan, 1998-2007.
Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Clarithromycin; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gemifloxacin; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Mutation; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Sequence Analysis, Protein; Taiwan; Tetracyclines; Tigecycline | 2010 |
Type IIA topoisomerase inhibition by a new class of antibacterial agents.
Topics: Anti-Bacterial Agents; Apoenzymes; Arginine; Aspartic Acid; Binding Sites; Catalytic Domain; Ciprofloxacin; Crystallography, X-Ray; DNA; DNA Cleavage; DNA Gyrase; DNA, Superhelical; Drug Design; Drug Resistance; Escherichia coli; Manganese; Models, Molecular; Protein Conformation; Quinolines; Quinolones; Staphylococcus aureus; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2010 |
Reduced expression of the vca0421 gene of Vibrio cholerae O1 results in innate resistance to ciprofloxacin.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Fluoroquinolones; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Vibrio cholerae O1 | 2010 |
Prevalence of mechanisms decreasing quinolone-susceptibility among Salmonella spp. clinical isolates.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Gastroenteritis; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Polymerase Chain Reaction; Quinolones; Salmonella; Salmonella Infections; Sequence Analysis, DNA; Spain | 2010 |
Spread of the qnrVC quinolone resistance determinant in Vibrio cholerae.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Chromosomes, Bacterial; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Transposable Elements; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Quinolones; Vibrio cholerae | 2011 |
Molecular characterization and phylogenetic analysis of quinolone resistance-determining regions (QRDRs) of gyrA, gyrB, parC and parE gene loci in viridans group streptococci isolated from adult patients with cystic fibrosis.
Topics: Adult; Anti-Bacterial Agents; Ciprofloxacin; Cystic Fibrosis; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Drug Utilization; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Quinolones; Sequence Analysis, DNA; Streptococcal Infections; Viridans Streptococci | 2011 |
Analysis of mechanisms involved in reduced susceptibility to ciprofloxacin in Salmonella enterica serotypes Typhi and Paratyphi A isolates from travellers to Southeast Asia.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Asia, Southeastern; Blood; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Genotype; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Paratyphoid Fever; Plasmids; Polymerase Chain Reaction; Quinolones; Salmonella paratyphi A; Salmonella typhi; Travel; Typhoid Fever | 2011 |
[Preliminary study on occurrence and health risk assessment of quinolone antibiotics in vegetables from Guangzhou, China].
Topics: Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Food Contamination; Norfloxacin; Quinolones; Risk Assessment; Urban Health; Vegetables | 2010 |
Comparison of different sample treatments for the analysis of quinolones in milk by capillary-liquid chromatography with laser induced fluorescence detection.
Topics: Animals; Chromatography, Liquid; Ciprofloxacin; Drug Residues; Fluoroquinolones; Lasers; Linear Models; Milk; Molecular Imprinting; Quinolones; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2011 |
Prevalence of plasmid-mediated quinolone resistance in Escherichia coli isolates in Wenzhou, Southern China, 2002-2008.
Topics: Acetyltransferases; Amino Acid Sequence; Anti-Infective Agents; China; Ciprofloxacin; Conjugation, Genetic; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Prevalence; Quinolones; Sequence Analysis, DNA | 2011 |
Chronic desensitization to quinolones in fixed drug eruption.
Topics: Adult; Ciprofloxacin; Cystic Fibrosis; Desensitization, Immunologic; Drug Eruptions; Erythema; Female; Humans; Pipemidic Acid; Quinolones | 2011 |
Diverse phenotypic and genotypic characterization among clinical Klebsiella pneumoniae and Escherichia coli isolates carrying plasmid-mediated quinolone resistance determinants.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Mutation; Plasmids; Quinolones | 2011 |
Characterization of Escherichia coli isolates from healthy food handlers in hospital.
Topics: Adolescent; Adult; beta-Lactamases; Ciprofloxacin; DNA Barcoding, Taxonomic; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Escherichia coli; Feces; Female; Food Handling; Food Service, Hospital; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Polymerase Chain Reaction; Quinolones; Sequence Analysis, DNA; Young Adult | 2011 |
Ciprofloxacin use and susceptibility of Gram-negative organisms to quinolone and non-quinolone antibiotics.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Utilization; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hospitals, University; Humans; Linear Models; Microbial Sensitivity Tests; Quinolones | 2011 |
Pre-clinical studies of a new quinolone (UB-8902) against Acinetobacter baumannii resistant to ciprofloxacin.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Infective Agents; Blood Bactericidal Activity; Ciprofloxacin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Lethal Dose 50; Maximum Tolerated Dose; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Molecular Conformation; Pneumonia; Quinolones | 2011 |
Citrobacter spp. as a source of qnrB Alleles.
Topics: Alleles; Anti-Bacterial Agents; Bacterial Proteins; Chromosomes, Bacterial; Ciprofloxacin; Citrobacter; Citrobacter freundii; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; Polymerase Chain Reaction; Quinolones; RNA, Ribosomal, 16S; Sequence Analysis, DNA | 2011 |
Wide dissemination of multidrug-resistant Shigella isolates in China.
Topics: Anti-Bacterial Agents; Bacterial Typing Techniques; Base Sequence; beta-Lactamases; Cephalosporins; China; Ciprofloxacin; Clavulanic Acids; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Dysentery, Bacillary; Enterobacteriaceae Infections; Gene Transfer, Horizontal; Humans; Microbial Sensitivity Tests; Mutation; Quinolones; Sequence Analysis, DNA; Serotyping; Shigella flexneri | 2011 |
Quinolone induction of qnrVS1 in Vibrio splendidus and plasmid-carried qnrS1 in Escherichia coli, a mechanism independent of the SOS system.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Mitomycin; Plasmids; Quinolones; SOS Response, Genetics; Vibrio | 2011 |
Molecular characterisation of the quinolone resistance-determining region (QRDR) of the parC gene locus in viridans-group streptococci.
Topics: Adult; Anti-Infective Agents; Child, Preschool; Ciprofloxacin; DNA Topoisomerase IV; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Northern Ireland; Quinolones; Streptococcus pneumoniae; Viridans Streptococci | 2011 |
Heterogeneity in the selection of quinolone target gene mutations upon exposure to ciprofloxacin in Yersinia enterocolitica.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Quinolones; Sequence Analysis, DNA; Yersinia enterocolitica; Yersinia Infections | 2011 |
In vivo sequential selection of Escherichia coli with topoisomerase- and efflux-mediated misleading quinolone resistance phenotypes.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Typing Techniques; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type I; Drug Resistance, Bacterial; Escherichia coli; Humans; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Ofloxacin; Phenotype; Quinolones; Selection, Genetic; Sequence Analysis, DNA | 2012 |
[Investigation of plasmid-mediated quinolone resistance in Pseudomonas aeruginosa strains isolated from cystic fibrosis patients].
Topics: Anti-Infective Agents; Ciprofloxacin; Cystic Fibrosis; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Multiplex Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones; R Factors; Respiratory System | 2011 |
Emergence of Proteus mirabilis harboring blaKPC-2 and qnrD in a Chinese Hospital.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; China; Ciprofloxacin; Clone Cells; Conjugation, Genetic; Cross Infection; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Genes, Bacterial; Humans; Plasmids; Polymerase Chain Reaction; Proteus Infections; Proteus mirabilis; Quinolones; Sequence Analysis, DNA | 2012 |
Fluoroquinolone use and resistance of Gram-positive bacteria causing healthcare-associated infections.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Gram-Negative Bacteria; Humans; Quinolones | 2012 |
Plasmid-mediated quinolone resistance in extended-spectrum-β-lactamase- and AmpC β-lactamase-producing Serratia marcescens in China.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; China; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Ofloxacin; Plasmids; Quinolones; Serratia Infections; Serratia marcescens | 2012 |
The first report of the qnrB19, qnrS1 and aac(6´)-Ib-cr genes in urinary isolates of ciprofloxacin-resistant Escherichia coli in Brazil.
Topics: Acetyltransferases; Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Proteins; Female; Humans; Microbial Sensitivity Tests; Mutation; Quinolones | 2012 |
Spectroscopic study of degradation products of ciprofloxacin, norfloxacin and lomefloxacin formed in ozonated wastewater.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Mass Spectrometry; Norfloxacin; Oxidation-Reduction; Ozone; Piperazine; Piperazines; Quinolones; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2012 |
Functional characterization of quinolone-resistant mechanisms in a lab-selected Salmonella enterica typhimurium mutant.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Microbial Sensitivity Tests; Nalidixic Acid; Point Mutation; Quinolones; Salmonella enterica; Salmonella typhimurium | 2013 |
Prevalence of plasmid-mediated quinolone resistance determinants among Escherichia coli isolated from food animals in Korea.
Topics: Animals; Anti-Bacterial Agents; Cattle; Cattle Diseases; Ciprofloxacin; Cluster Analysis; DNA Gyrase; DNA Mutational Analysis; DNA Primers; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Phenotype; Phylogeny; Prevalence; Quinolones; R Factors; Republic of Korea; Swine; Swine Diseases | 2012 |
Potent in vitro antibacterial activity of DS-8587, a novel broad-spectrum quinolone, against Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Quinolones | 2013 |
3-Aryl-4-methyl-2-quinolones targeting multiresistant Staphylococcus aureus bacteria.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Cell Line; Cell Survival; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Humans; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Quinolones; Staphylococcus aureus | 2013 |
Interactions between new quinolone antibacterials and diagnostic drug containing manganese.
Topics: Algorithms; Anti-Bacterial Agents; Chelating Agents; Chemistry, Pharmaceutical; Ciprofloxacin; Drug Interactions; Levofloxacin; Manganese Compounds; Ofloxacin; Quinolones | 2013 |
Topoisomerase IV-quinolone interactions are mediated through a water-metal ion bridge: mechanistic basis of quinolone resistance.
Topics: Anti-Bacterial Agents; Bacillus anthracis; Cations, Divalent; Ciprofloxacin; DNA; DNA Cleavage; DNA Topoisomerase IV; Drug Resistance; Magnesium; Metals; Mutation; Quinazolinones; Quinolones; Water | 2013 |
Prevalence and characterization of plasmid-mediated quinolone resistance genes in Salmonella isolated from poultry in Korea.
Topics: Animals; Blotting, Southern; Ciprofloxacin; DNA Primers; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Gene Transfer, Horizontal; Levofloxacin; Microbial Sensitivity Tests; Nalidixic Acid; Plasmids; Polymerase Chain Reaction; Poultry; Poultry Diseases; Quinolones; Republic of Korea; Salmonella; Salmonella Infections, Animal | 2013 |
Effect of pH on the in vitro susceptibility of planktonic and biofilm-grown Proteus mirabilis to the quinolone antimicrobials.
Topics: Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Plankton; Proteus mirabilis; Quinolones | 2013 |
Assessment of synergistic interactions of danofloxacin and orbifloxacin against quinolone-resistant Escherichia coli isolated from animals by the checkerboard and time-kill methods.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones | 2013 |
OqxAB, a quinolone and olaquindox efflux pump, is widely distributed among multidrug-resistant Klebsiella pneumoniae isolates of human origin.
Topics: Americas; Animals; Anti-Bacterial Agents; Asia; Australia; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Genes, MDR; Humans; Klebsiella Infections; Klebsiella pneumoniae; Quinolones; Quinoxalines; Swine; Swine Diseases | 2013 |
Bacterial resistance studies using in vitro dynamic models: the predictive power of the mutant prevention and minimum inhibitory antibiotic concentrations.
Topics: Anti-Bacterial Agents; Area Under Curve; Ciprofloxacin; Escherichia coli; Microbial Sensitivity Tests; Mutation; Quinolones | 2013 |
Short communication: In vitro antimicrobial susceptibility of Mycoplasma agalactiae strains isolated from dairy goats.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enrofloxacin; Erythromycin; Female; Fluoroquinolones; Goat Diseases; Goats; Macrolides; Microbial Sensitivity Tests; Mycoplasma agalactiae; Mycoplasma Infections; Quinolones; Spain; Tetracycline | 2013 |
Quinolone-resistant Escherichia coli from the faecal microbiota of healthy volunteers after ciprofloxacin exposure are highly adapted to a commensal lifestyle.
Topics: Adolescent; Adult; Animals; Anti-Bacterial Agents; Ciprofloxacin; Dogs; Drug Resistance, Bacterial; Escherichia coli; Feces; Female; Healthy Volunteers; Humans; Male; Mice; Middle Aged; Quinolones; Symbiosis; Young Adult | 2014 |
Analysis of quinolone-resistance in commensal and diarrheagenic Escherichia coli isolates from infants in Lima, Peru.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Dipeptides; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Feces; Female; Humans; Infant; Male; Microbial Sensitivity Tests; Nalidixic Acid; Peru; Prevalence; Quinolones | 2014 |
Characterization of variables that may influence ozenoxacin in susceptibility testing, including MIC and MBC values.
Topics: Aminopyridines; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Hydrogen-Ion Concentration; Levofloxacin; Microbial Sensitivity Tests; Quinolones | 2014 |
The association between occurrence of plasmid-mediated quinolone resistance and ciprofloxacin resistance in Escherichia coli isolates of different origins.
Topics: Animals; Anti-Bacterial Agents; China; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Food Microbiology; Humans; Microbial Sensitivity Tests; Plasmids; Prevalence; Quinolones | 2014 |
Prevalence and characterisation of quinolone resistance mechanisms in Salmonella spp.
Topics: Amino Acid Substitution; Animal Feed; Animals; Bacterial Proteins; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Microbial Sensitivity Tests; Nalidixic Acid; Phylogeny; Poland; Prevalence; Quinolones; Salmonella; Salmonella Infections, Animal; Species Specificity | 2014 |
Determination of five quinolone antibiotic residues in foods by micellar electrokinetic capillary chromatography with quantum dot indirect laser-induced fluorescence.
Topics: Animal Feed; Animals; Anti-Bacterial Agents; Cadmium Compounds; Chromatography, Micellar Electrokinetic Capillary; Ciprofloxacin; Enrofloxacin; European Union; Fluorescence; Fluoroquinolones; Hydrogen-Ion Concentration; Japan; Lasers; Limit of Detection; Loxapine; Norfloxacin; Quantum Dots; Quinolones; Spectrometry, Fluorescence; Tellurium | 2014 |
[Simultaneous determination of clopidol, sulfonamide and quinolone residues in chickens by ultra performance liquid chromatography-tandem mass spectrometry].
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Clopidol; Drug Residues; Enrofloxacin; Fluoroquinolones; Food Contamination; Hexanes; Meat; Norfloxacin; Ofloxacin; Quinolones; Sulfanilamide; Sulfanilamides; Sulfonamides; Tandem Mass Spectrometry | 2013 |
Impact of quinolone-resistance acquisition on biofilm production and fitness in Salmonella enterica.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Ciprofloxacin; Drug Resistance, Bacterial; Gene Expression Profiling; Humans; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Quinolones; Real-Time Polymerase Chain Reaction; Salmonella Infections; Salmonella typhimurium; Selection, Genetic; Serial Passage | 2014 |
High levels of multiresistance in quinolone resistant urinary tract isolates of Escherichia coli from Norway; a non clonal phenomen?
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Norway; Phylogeny; Quinolones; Species Specificity; Urinary Tract | 2014 |
Lactococcus garvieae carries a chromosomally encoded pentapeptide repeat protein that confers reduced susceptibility to quinolones in Escherichia coli producing a cytotoxic effect.
Topics: Anti-Bacterial Agents; Cell Membrane; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Gene Expression; Lactococcus; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Nalidixic Acid; Quinolones; Recombinant Proteins | 2014 |
Analysis of quinolone antibiotics in eggs: preparation and characterization of a raw material for method validation and quality control.
Topics: Anti-Bacterial Agents; Chromatography, Liquid; Ciprofloxacin; Eggs; Enrofloxacin; Fluoroquinolones; Food Contamination; Norfloxacin; Oxolinic Acid; Quality Control; Quinolones; Reproducibility of Results | 2012 |
Detection of plasmid-mediated qnr genes among the quinolone-resistant Escherichia coli isolates in Iran.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Humans; Iran; Microbial Sensitivity Tests; Nalidixic Acid; Plasmids; Quinolones; Urinary Tract Infections | 2014 |
Prevalence and characterization of quinolone resistance mechanisms in commensal Escherichia coli isolated from slaughter animals in Poland, 2009-2012.
Topics: Anti-Infective Agents; Chromosomes, Bacterial; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Plasmids; Poland; Quinolones; Salmonella | 2014 |
Responses of plasmid-mediated quinolone resistance genes and bacterial taxa to (fluoro)quinolones-containing manure in arable soil.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Enrofloxacin; Fluoroquinolones; Genes, Bacterial; Gram-Negative Bacteria; Manure; Norfloxacin; Plasmids; Quinolones; Selection, Genetic; Soil; Species Specificity; Time Factors | 2015 |
Association of mutation patterns in GyrA and ParC genes with quinolone resistance levels in lactic acid bacteria.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Ciprofloxacin; Cultured Milk Products; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Resistance, Bacterial; Enterococcus; Lactic Acid; Lactobacillus; Microbial Sensitivity Tests; Mutation; Norfloxacin; Quinolones; Yogurt | 2015 |
In vitro selection of mutants resistant to ozenoxacin compared with levofloxacin and ciprofloxacin in Gram-positive cocci.
Topics: Aminopyridines; Anti-Bacterial Agents; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Polymerase Chain Reaction; Quinolones; Selection, Genetic; Sequence Analysis, DNA | 2015 |
Genetic profiles of fluoroquinolone-nonsusceptible Klebsiella pneumoniae among cephalosporin-resistant K. pneumoniae.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Genes, Bacterial; Japan; Klebsiella pneumoniae; Quinolones | 2015 |
[Prevalence and characterization of cefotaxime and ciprofloxacin co-resistant Escherichia coli isolates in retail chicken carcasses].
Topics: Animals; Anti-Bacterial Agents; Cefotaxime; Chickens; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Meat; Phylogeny; Plasmids; Polymerase Chain Reaction; Prevalence; Quinolones; Risk Assessment | 2014 |
Characterisation of novel mutations involved in quinolone resistance in Escherichia coli isolated from imported shrimp.
Topics: Anti-Bacterial Agents; Biological Transport, Active; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Microbial Sensitivity Tests; Models, Molecular; Mutation, Missense; Nalidixic Acid; Point Mutation; Polymerase Chain Reaction; Protein Conformation; Quinolones; Seafood; Selection, Genetic; Sequence Analysis, DNA | 2015 |
[Salmonella enterica with nonclassical quinolone resistance phenotype in pediatric patients].
Topics: Anti-Bacterial Agents; Child; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Phenotype; Quinolones; Salmonella enterica; Salmonella Infections | 2015 |
To cipro or not to cipro: bilateral achilles ruptures with the use of quinolones.
Topics: Achilles Tendon; Aged, 80 and over; Ciprofloxacin; Cytochrome P-450 CYP1A2 Inhibitors; Humans; Magnetic Resonance Imaging; Male; Quinolones; Rupture; Tendon Injuries | 2015 |
Molecular characterization of quinolone resistance mechanisms and extended-spectrum β-lactamase production in Escherichia coli isolated from dogs.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Ciprofloxacin; DNA Topoisomerase IV; Dogs; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Infections; Feces; Genotype; Microbial Sensitivity Tests; Mutation; Phylogeny; Quinolones | 2015 |
[Role of double strand DNA break repair for quinolone sensitivity in Escherichia coli: therapeutic implications].
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; DNA Breaks, Double-Stranded; DNA Helicases; DNA Repair; DNA Replication; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Exodeoxyribonuclease V; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Targeted Therapy; Nalidixic Acid; Norfloxacin; Quinolones; Rec A Recombinases; Recombinational DNA Repair; Serine Endopeptidases; SOS Response, Genetics | 2015 |
Design and biological evaluation of novel quinolone-based metronidazole derivatives as potent Cu(2+) mediated DNA-targeting antibacterial agents.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Chemistry Techniques, Synthetic; Ciprofloxacin; Copper; DNA, Bacterial; Drug Evaluation, Preclinical; Fibroblasts; Fluoroquinolones; HEK293 Cells; Humans; Metronidazole; Mice; Microbial Sensitivity Tests; Molecular Targeted Therapy; Norfloxacin; Pseudomonas aeruginosa; Quinolones; Structure-Activity Relationship | 2015 |
[Determination of 25 quinolones in cosmetics by liquid chromatography-tandem mass spectrometry].
Topics: Chromatography, Liquid; Ciprofloxacin; Cosmetics; Drug Residues; Enrofloxacin; Fluoroquinolones; Hexanes; Norfloxacin; Ofloxacin; Quinolones; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2015 |
Amino acid substitutions in GyrA affect quinolone susceptibility in Salmonella typhimurium.
Topics: Amino Acid Substitution; Ciprofloxacin; DNA Gyrase; Escherichia coli; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Quinolones; Salmonella typhimurium | 2016 |
Adjuvant effect of cranberry proanthocyanidin active fraction on antivirulent property of ciprofloxacin against Pseudomonas aeruginosa.
Topics: 4-Butyrolactone; Acyl-Butyrolactones; Adjuvants, Pharmaceutic; Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Drug Synergism; Microbial Sensitivity Tests; Molecular Docking Simulation; Plant Extracts; Proanthocyanidins; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones; Quorum Sensing; Vaccinium macrocarpon; Virulence | 2016 |
Quinolone Resistance Mechanisms Among Salmonella enterica in Malaysia.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Conjugation, Genetic; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Gene Expression Regulation, Bacterial; Humans; Malaysia; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Plasmids; Prevalence; Quinolones; Salmonella enterica; Salmonella Infections | 2016 |
Impact of mutations in DNA gyrase genes on quinolone resistance in Campylobacter jejuni.
Topics: Anti-Bacterial Agents; Campylobacter jejuni; Ciprofloxacin; DNA Gyrase; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Quinolones; Recombinant Proteins; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2016 |
Urinary Tract Physiological Conditions Promote Ciprofloxacin Resistance in Low-Level-Quinolone-Resistant Escherichia coli.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Genotype; Healthy Volunteers; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Mutation; Prospective Studies; Quinolones; Urinary Tract Infections | 2016 |
Characteristics of bacterial pathogens associated with acute diarrhea in children under 5 years of age: a hospital-based cross-sectional study.
Topics: Anti-Infective Agents; Campylobacter jejuni; Child; Child Health Services; Child, Preschool; China; Ciprofloxacin; Cross-Sectional Studies; Demography; Diarrhea; Drug Resistance, Microbial; Escherichia coli; Female; Hospitalization; Humans; Infant; Male; Prospective Studies; Quinolones; Salmonella; Shigella | 2016 |
In Vitro Resistance Development to Nemonoxacin in Streptococcus pneumoniae: A Unique Profile for a Novel Nonfluorinated Quinolone.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Culture Media; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gene Expression; Microbial Sensitivity Tests; Mutation; Quinolones; Sequence Analysis, DNA; Streptococcus pneumoniae; Structure-Activity Relationship | 2016 |
Molecular characterisation of the clonal emergence of high-level ciprofloxacin-monoresistant Haemophilus influenzae in the Region of Southern Denmark.
Topics: Aged; Bacterial Typing Techniques; Ciprofloxacin; Denmark; Drug Resistance, Bacterial; Female; Genes, Bacterial; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Male; Microbial Sensitivity Tests; Multilocus Sequence Typing; Mutation; Quinolones | 2016 |
The Emergence of Quinolone Resistant Shigella sonnei, Pondicherry, India.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Bacterial; Dysentery, Bacillary; Feces; Humans; India; Levofloxacin; Microbial Sensitivity Tests; Plasmids; Quinolones; Shigella sonnei | 2016 |
Impact of AAC(6')-Ib-cr in combination with chromosomal-mediated mechanisms on clinical quinolone resistance in Escherichia coli.
Topics: Animals; Anti-Bacterial Agents; Chromosomes, Bacterial; Ciprofloxacin; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Genes, Bacterial; Male; Mice, Inbred C57BL; Microbial Sensitivity Tests; Microbial Viability; Norfloxacin; Peritonitis; Plasmids; Quinolones; Sepsis; Virulence | 2016 |
Analysis of plasmid-mediated quinolone and oxyimino-cephalosporin resistance mechanisms in Uruguayan Salmonella enterica isolates from 2011-2013.
Topics: Anti-Bacterial Agents; Cephalosporin Resistance; Ciprofloxacin; Humans; Microbial Sensitivity Tests; Plasmids; Quinolones; Salmonella enterica; Salmonella Infections; Uruguay | 2016 |
Prevalence of Plasmid-Mediated Quinolone Resistance Genes in Clinical Enterobacteria from Argentina.
Topics: Anti-Bacterial Agents; Argentina; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Integrons; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Plasmids; Prevalence; Quinolones | 2017 |
Travelers' Diarrhea-Associated Enterotoxigenic Escherichia coli gyrA Mutants and Quinolone Antibiotic Affinity: A Molecular Dynamics Simulation and Residue Interaction Network Analysis.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Developing Countries; Diarrhea; DNA Gyrase; Drug Design; Drug Resistance, Bacterial; Enterotoxigenic Escherichia coli; Escherichia coli Infections; Humans; Molecular Dynamics Simulation; Mutation; Protein Domains; Protein Structure, Secondary; Quinolones; Risk Factors; Topoisomerase II Inhibitors; Travel | 2016 |
Characterization of antimicrobial resistance and quinolone resistance factors in high-level ciprofloxacin-resistant Enterococcus faecalis and Enterococcus faecium isolates obtained from fresh produce and fecal samples of patients.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Crops, Agricultural; Drug Resistance, Bacterial; Enterococcus faecalis; Enterococcus faecium; Feces; Food Contamination; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Quinolones | 2017 |
Antimicrobial Resistance of Campylobacter Species Isolated from Broilers in Live Bird Markets in Shanghai, China.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Campylobacter coli; Campylobacter jejuni; Carrier Proteins; Chickens; China; Ciprofloxacin; Clindamycin; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Erythromycin; Food Contamination; Food Microbiology; Gentamicins; Kanamycin; Methyltransferases; Microbial Sensitivity Tests; Poultry; Quinolones; RNA, Ribosomal, 23S; Tetracyclines | 2017 |
Plasmid-mediated quinolone resistance determinants among Gram-negative bacteraemia isolates: a hidden threat.
Topics: Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli; Gram-Negative Bacterial Infections; Greece; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Quinolones; R Factors; Stenotrophomonas maltophilia | 2017 |
Prevalence and characterisation of quinolone resistance genes in Aeromonas spp. isolated from pet turtles in South Korea.
Topics: Aeromonas; Amino Acid Substitution; Animals; Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Ofloxacin; Plasmids; Polymerase Chain Reaction; Quinolones; Republic of Korea; Turtles | 2017 |
Emergence of Salmonella enterica serovar Indiana and California isolates with concurrent resistance to cefotaxime, amikacin and ciprofloxacin from chickens in China.
Topics: Amikacin; Animals; Anti-Bacterial Agents; beta-Lactamases; Cefotaxime; Chickens; China; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Methyltransferases; Microbial Sensitivity Tests; Multilocus Sequence Typing; Quinolones; RNA, Ribosomal, 16S; Salmonella enterica | 2017 |
Drug repurposing: An approach to tackle drug resistance in S. typhimurium.
Topics: Bacterial Proteins; Ciprofloxacin; Databases, Factual; DNA Gyrase; Drug Evaluation, Preclinical; Drug Repositioning; Drug Resistance, Bacterial; Flufenamic Acid; Molecular Dynamics Simulation; Nalidixic Acid; Quinolones; Salmonella typhimurium; Topoisomerase II Inhibitors | 2018 |
Quantitative and automated MALDI-TOF MS-based detection of the plasmid-mediated quinolone resistance determinant AAC(6')-Ib-cr in Enterobacteriaceae.
Topics: Acetylation; Acetyltransferases; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Enterobacteriaceae; Norfloxacin; Plasmids; Quinolones; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2017 |
The role of ATP pools in persister cell formation in (fluoro)quinolone-susceptible and -resistant strains of Salmonella enterica ser. Typhimurium.
Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Mutation; Nalidixic Acid; Quinolones; Salmonella Infections, Animal; Salmonella typhimurium | 2017 |
Molecular Characterization of Fluoroquinolone Resistance Mechanisms of Campylobacter Isolates from Duck Meats.
Topics: Animals; Campylobacter; Campylobacter jejuni; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Ducks; Fluoroquinolones; Meat; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Quinolines; Quinolones | 2017 |
Exploring quinolone resistance-determining region in
Topics: Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Gonorrhea; Humans; India; Mutation; Neisseria gonorrhoeae; Quinolones | 2017 |
Discovery of a Novel Fluoroquinolone Antibiotic Candidate WFQ-228 with Potent Antimicrobial Activity and the Potential to Overcome Major Drug Resistance.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Quinolones; Structure-Activity Relationship | 2018 |
Arcobacter butzleri Ciprofloxacin Resistance: Point Mutations in DNA Gyrase A and Role on Fitness Cost.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Arcobacter; Biofilms; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Microbial Sensitivity Tests; Point Mutation; Quinolones | 2018 |
Prevalence of quinolone resistance genes, copper resistance genes, and the bacterial communities in a soil-ryegrass system co-polluted with copper and ciprofloxacin.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Copper; Drug Resistance, Microbial; Environmental Monitoring; Genes, Bacterial; Lolium; Plasmids; Prevalence; Quinolones; Soil; Soil Microbiology; Soil Pollutants | 2018 |
Upconversion particle@Fe
Topics: Animals; Biosensing Techniques; Ciprofloxacin; Enoxacin; Enrofloxacin; Erbium; Fishes; Fleroxacin; Fluorescent Dyes; Fluorides; Fluoroquinolones; Levofloxacin; Magnetite Nanoparticles; Molecular Imprinting; Quinolones; Reproducibility of Results; Seafood; Ytterbium; Yttrium | 2018 |
Microbiology and antimicrobial susceptibility of otitis externa: a changing pattern of antimicrobial resistance.
Topics: Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Candida; Candidiasis; Ciprofloxacin; Drug Resistance, Bacterial; Female; Gentamicins; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Otitis Externa; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones; Staphylococcal Infections; Staphylococcus aureus | 2018 |
Emergence of resistance to ciprofloxacin in Neisseria meningitidis in Brazil.
Topics: Anti-Bacterial Agents; Brazil; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Meningococcal Infections; Microbial Sensitivity Tests; Multilocus Sequence Typing; Mutation; Neisseria gonorrhoeae; Neisseria meningitidis; Quinolones | 2018 |
CrpP Is a Novel Ciprofloxacin-Modifying Enzyme Encoded by the Pseudomonas aeruginosa pUM505 Plasmid.
Topics: Bacterial Proteins; Ciprofloxacin; Gene Expression Regulation, Bacterial; Phosphorylation; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones; Virulence Factors | 2018 |
Plasmid-Mediated Quinolone Resistance in Gram-Negative Pathogens Isolated from Cancer Patients in Egypt.
Topics: Anti-Bacterial Agents; beta-Lactamases; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Egypt; Fluoroquinolones; Genes, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Neoplasms; Plasmids; Quinolones | 2018 |
Mycoplasma hominis shows strain-dependent increase in resistance to selected antibiotics after symbiosis with Trichomonas vaginalis.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Female; Humans; Metronidazole; Microbial Sensitivity Tests; Mutation; Mycoplasma hominis; Mycoplasma Infections; Quinolones; Symbiosis; Trichomonas vaginalis; Trichomonas Vaginitis; Vagina | 2018 |
Identification and Characterization of Salmonella enterica Serotype Newport Isolates with Decreased Susceptibility to Ciprofloxacin in the United States.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Microbial Sensitivity Tests; Plasmids; Quinolones; Salmonella enterica; Serogroup; United States | 2018 |
CRISPR/Cas9/sgRNA-mediated targeted gene modification confirms the cause-effect relationship between gyrA mutation and quinolone resistance in Escherichia coli.
Topics: Amino Acid Motifs; Animals; Anti-Bacterial Agents; Chickens; Ciprofloxacin; CRISPR-Cas Systems; DNA Gyrase; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Gene Editing; Microbial Sensitivity Tests; Mutation; Poultry Diseases; Quinolines; Quinolones; RNA, Bacterial; Swine; Swine Diseases | 2018 |
First description of plasmid mediated quinolone resistance genes in salmonella isolates from Saudi hospitals.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefotaxime; Child; Child, Preschool; Ciprofloxacin; DNA Topoisomerases; Drug Resistance, Bacterial; Female; Fluoroquinolones; Humans; Infant; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Plasmids; Polymerase Chain Reaction; Quinolones; Salmonella; Salmonella Infections; Saudi Arabia; Young Adult | 2018 |
Genotypic Resistance to Quinolone and Tetracycline in Salmonella Dublin Strains Isolated from Humans and Animals in Brazil.
Topics: Animals; Anti-Bacterial Agents; Brazil; Cattle; Ciprofloxacin; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Plasmids; Polymerase Chain Reaction; Quinolones; Salmonella enterica; Tetracycline | 2019 |
Patterns of Fluoroquinolone Resistance in Enterobacteriaceae Isolated from the Assiut University Hospitals, Egypt: A Comparative Study.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Egypt; Enterobacteriaceae Infections; Escherichia coli; Fluoroquinolones; Hospitals, University; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Plasmids; Quinolones | 2019 |
Detection of plasmid-mediated quinolone resistance genes in β-lactamase-producing Escherichia coli isolates from layer hens.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Chickens; Ciprofloxacin; Electrophoresis, Gel, Pulsed-Field; Enrofloxacin; Escherichia coli; Female; Plasmids; Quinolones | 2019 |
(+)-Catechin potentiates the oxidative response of Acinetobacter baumannii to quinolone-based antibiotics.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Catechin; Ciprofloxacin; Drug Synergism; Gemifloxacin; Microbial Sensitivity Tests; Oxidative Stress; Quinolones; Reactive Oxygen Species | 2019 |
Ivacaftor, a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator, Enhances Ciprofloxacin Activity Against Pseudomonas aeruginosa.
Topics: Aminophenols; Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Synergism; Pseudomonas aeruginosa; Quinolones | 2019 |
Quinolone resistance phenotype and genetic characterization of Salmonella enterica serovar Pullorum isolates in China, during 2011 to 2016.
Topics: Animals; Anti-Bacterial Agents; Chickens; China; Ciprofloxacin; Drug Resistance, Bacterial; Genotype; Humans; Microbial Sensitivity Tests; Multilocus Sequence Typing; Phenotype; Poultry Diseases; Quinolones; Salmonella enterica; Salmonella Infections, Animal; Serogroup | 2018 |
First report of the new emerging global clone ST1193 among clinical isolates of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli from Germany.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamases; Cefotaxime; Ceftazidime; Child; Child, Preschool; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Germany; Humans; Infant; Infant, Newborn; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Epidemiology; Multilocus Sequence Typing; Plasmids; Polymerase Chain Reaction; Prevalence; Quinolones; Serogroup; Virulence Factors; Young Adult | 2019 |
In-vitro evaluation of a ciprofloxacin- and ivacaftor-coated sinus stent against Pseudomonas aeruginosa biofilms.
Topics: Aminophenols; Anti-Bacterial Agents; Biofilms; Chloride Channel Agonists; Ciprofloxacin; Drug Liberation; Drug-Eluting Stents; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones | 2019 |
Synthesis, characterization and biological evaluation of Co(III) complexes with quinolone drugs.
Topics: Animals; Anti-Bacterial Agents; Cattle; Cell Line, Tumor; Ciprofloxacin; Cobalt; Coordination Complexes; DNA; DNA Gyrase; Humans; Intercalating Agents; Ligands; Microbial Sensitivity Tests; Quinolones; Topoisomerase II Inhibitors | 2019 |
Conjugal transfer of PMQR from uropathogenic E.coli under high ciprofloxacin selection pressure generates gyrA mutation.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Conjugation, Genetic; DNA Gyrase; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Plasmids; Quinolones; Recombination, Genetic; Uropathogenic Escherichia coli | 2019 |
Quinolone and Macrolide-Resistant
Topics: Anti-Bacterial Agents; Campylobacter Infections; Campylobacter jejuni; Child; Child, Preschool; Ciprofloxacin; Cross-Sectional Studies; Diarrhea; DNA, Bacterial; Drug Resistance, Bacterial; Erythromycin; Female; Flagellin; Gastroenteritis; Genotype; Humans; Infant; Iran; Macrolides; Male; Microbial Sensitivity Tests; Quinolones; RNA, Ribosomal, 23S; Tetracycline | 2019 |
Highly Water-Stable Dye@Ln-MOFs for Sensitive and Selective Detection toward Antibiotics in Water.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Norfloxacin; Quinolones; Reproducibility of Results; Water; X-Ray Diffraction | 2019 |
Genomic characterization of multidrug-resistant ESBL-producing Klebsiella pneumoniae isolated from a Ghanaian teaching hospital.
Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactamases; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Genomics; Ghana; Hospitals, Teaching; Humans; Klebsiella Infections; Klebsiella pneumoniae; Plasmids; Quinolones | 2019 |
Cysteine auxotrophy drives reduced susceptibility to quinolones and paraquat by inducing the expression of efflux-pump systems and detoxifying enzymes in S. Typhimurium.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Cysteine; Drug Resistance, Multiple, Bacterial; Gene Deletion; Gene Expression; Genes, Bacterial; Humans; Levofloxacin; Membrane Transport Proteins; Mutation; Nalidixic Acid; Paraquat; Quinolones; Reactive Oxygen Species; Salmonella typhimurium; Sulfur | 2019 |
[From surveillance to action: Modifying therapeutic behaviours in gonococcal infections].
Topics: Adolescent; Adult; Age Distribution; Aged; Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Ciprofloxacin; Controlled Before-After Studies; Doxycycline; Female; Gonorrhea; Humans; Incidence; Male; Medication Adherence; Microbiology; Middle Aged; Neisseria gonorrhoeae; Physicians, Primary Care; Population Surveillance; Quinolones; Spain; Young Adult | 2020 |
Assessment of antibiotic resistance in bacteriophage-insensitive Klebsiella pneumoniae.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteriophages; beta-Lactamases; Cefotaxime; Cephalothin; Chloramphenicol; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Gene Expression Regulation, Bacterial; Humans; Klebsiella pneumoniae; Levofloxacin; Phage Therapy; Quinolones | 2019 |
Characterization of plasmid mediated quinolone resistance determinants in ciprofloxacin resistant-Escherichia coli from chicken meat produced by integrated broiler operations in Korea.
Topics: Animal Husbandry; Animals; Anti-Bacterial Agents; Chickens; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Meat; Microbial Sensitivity Tests; Plasmids; Quinolones; Republic of Korea | 2019 |
Commercial Quinolone Ear Drops Cause Perforations in Intact Rat Tympanic Membranes.
Topics: Animals; Ciprofloxacin; Dexamethasone; Female; Hydrocortisone; Male; Methylprednisolone Hemisuccinate; Middle Ear Ventilation; Neomycin; Ofloxacin; Prostheses and Implants; Quinolones; Random Allocation; Rats; Rats, Sprague-Dawley; Tympanic Membrane; Tympanic Membrane Perforation | 2019 |
Combined HQSAR method and molecular docking study on genotoxicity mechanism of quinolones with higher genotoxicity.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Damage; Gram-Negative Bacteria; Gram-Positive Bacteria; Molecular Docking Simulation; Quantitative Structure-Activity Relationship; Quinolones; Structure-Activity Relationship | 2019 |
Phylogenetic relationships, virulence and antimicrobial resistance properties of Klebsiella sp. isolated from pet turtles in Korea.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Ciprofloxacin; Drug Resistance, Bacterial; Humans; Klebsiella Infections; Klebsiella oxytoca; Klebsiella pneumoniae; Microbial Sensitivity Tests; Phylogeny; Plasmids; Quinolones; Republic of Korea; RNA, Ribosomal, 16S; Turtles; Virulence | 2020 |
Impact of co-existence of PMQR genes and QRDR mutations on fluoroquinolones resistance in Enterobacteriaceae strains isolated from community and hospital acquired UTIs.
Topics: Adult; Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Cross Infection; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Fluoroquinolones; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Plasmids; Quinolones; Urinary Tract Infections; Young Adult | 2019 |
Development of quinolone resistance and prevalence of different virulence genes among Shigella flexneri and Shigella dysenteriae in environmental water samples.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Humans; India; Membrane Transport Proteins; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Plasmids; Prevalence; Quinolones; Shigella dysenteriae; Shigella flexneri; Virulence | 2020 |
Controlled delivery of ciprofloxacin and ivacaftor via sinus stent in a preclinical model of Pseudomonas sinusitis.
Topics: Aminophenols; Animals; Chronic Disease; Ciprofloxacin; Maxillary Sinus; Pseudomonas; Pseudomonas Infections; Quinolones; Rabbits; Sinusitis; Stents | 2020 |
Discovery of seven novel mutations of gyrB, parC and parE in Salmonella Typhi and Paratyphi strains from Jiangsu Province of China.
Topics: Anti-Bacterial Agents; Bacterial Proteins; China; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Quinolones; Salmonella paratyphi A; Salmonella typhi | 2020 |
Prevalence and Characterization of Plasmid-Mediated Quinolone Resistance Determinants
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Chickens; Ciprofloxacin; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Food Supply; Humans; Intracellular Signaling Peptides and Proteins; Microbial Sensitivity Tests; Plasmids; Quinolones; Republic of Korea | 2020 |
Role of low-level quinolone resistance in generating tolerance in Escherichia coli under therapeutic concentrations of ciprofloxacin.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Escherichia coli; Microbial Sensitivity Tests; Mutation; Quinolones | 2020 |
Phenotypic and genotypic quinolone resistance in Escherichia coli underlining GyrA83/87 mutations as a target to detect ciprofloxacin resistance.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Escherichia coli; France; Genotype; Microbial Sensitivity Tests; Mutation; Phenotype; Plasmids; Quinolones | 2020 |
The use of eugenol in combination with cefotaxime and ciprofloxacin to combat ESBL-producing quinolone-resistant pathogenic Enterobacteriaceae.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefotaxime; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Drug Synergism; Enterobacteriaceae; Eugenol; Gene Expression Regulation, Bacterial; Humans; Microbial Sensitivity Tests; Quinolones | 2020 |
Multi-phase distribution, spatiotemporal variation and risk assessment of antibiotics in a typical urban-rural watershed.
Topics: Anti-Bacterial Agents; China; Ciprofloxacin; Cities; Environmental Monitoring; Geologic Sediments; Lakes; Norfloxacin; Particulate Matter; Quinolones; Risk Assessment; Rivers; Seasons; Tetracycline; Water Pollutants, Chemical | 2020 |
Ciprofloxacin usage at a local hospital.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Hospitals; Humans; Norway; Quinolones | 2020 |
Occurrence of Campylobacter spp. in Swedish calves, common sequence types and antibiotic resistance patterns.
Topics: Animals; Anti-Bacterial Agents; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Cattle; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Feces; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Poultry; Quinolones; Sweden; Whole Genome Sequencing | 2021 |
Combined toxicity characteristics and regulation of residual quinolone antibiotics in water environment.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Molecular Docking Simulation; Quinolones; Water | 2021 |
Basophil activation test in the diagnosis of hypersensitivity reactions to quinolones in a real-life setting.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Basophil Degranulation Test; Ciprofloxacin; Drug Hypersensitivity; Female; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Norfloxacin; Quinolones; Skin Tests; Young Adult | 2021 |
Simultaneous quantification of plasma levels of 12 antimicrobial agents including carbapenem, anti-methicillin-resistant Staphylococcus aureus agent, quinolone and azole used in intensive care unit using UHPLC-MS/MS method.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Azoles; Carbapenems; Chromatography, High Pressure Liquid; Ciprofloxacin; Daptomycin; Doripenem; Drug Monitoring; Female; Fluconazole; Fluoroquinolones; Humans; Intensive Care Units; Levofloxacin; Linezolid; Male; Meropenem; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazines; Oxazolidinones; Quinolones; Tandem Mass Spectrometry; Tetrazoles; Voriconazole | 2021 |
Analyzing Possible Native Functions of the Quinolone Resistance Gene
Topics: Bacterial Proteins; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Quinolones; Vibrio vulnificus | 2021 |
Escherichia coli GyrA Tower Domain Interacts with QnrB1 Loop B and Plays an Important Role in QnrB1 Protection from Quinolone Inhibition.
Topics: Ciprofloxacin; DNA Gyrase; Escherichia coli; Escherichia coli Proteins; Mutation; Quinolones | 2021 |
Identification of pathogens isolated in acute external otitis cases and evaluation of aminoglycoside and quinolone sensitivity.
Topics: Acute Disease; Administration, Topical; Adult; Age Factors; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Otitis Externa; Pseudomonas; Quinolones; Retrospective Studies; Seasons | 2021 |
Wide spread and diversity of mutation in the gyrA gene of quinolone-resistant Corynebacterium striatum strains isolated from three tertiary hospitals in China.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ciprofloxacin; Corynebacterium; Corynebacterium Infections; Cross Infection; DNA Gyrase; Drug Resistance, Multiple; Female; Genotype; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Quinolones; Tertiary Care Centers | 2021 |
Fluoroquinolone resistance contributing mechanisms and genotypes of ciprofloxacin- unsusceptible Pseudomonas aeruginosa strains in Iran: emergence of isolates carrying qnr/aac(6)-Ib genes.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Genotype; Humans; Iran; Microbial Sensitivity Tests; Plasmids; Pseudomonas aeruginosa; Quinolones; Random Amplified Polymorphic DNA Technique | 2022 |
Occurrence of plasmid-mediated quinolone resistance genes in Pseudomonas aeruginosa strains isolated from clinical specimens in southwest Iran: a multicentral study.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Iran; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quinolones | 2022 |
Systemic quinolones and risk of retinal detachment III: a nested case-control study using a US electronic health records database.
Topics: Aged; Anti-Bacterial Agents; Case-Control Studies; Ciprofloxacin; Electronic Health Records; Female; Humans; Middle Aged; Quinolones; Retinal Detachment | 2022 |
Investigation of plasmid-mediated quinolone resistance genes among clinical isolates of Klebsiella pneumoniae in southwest Iran.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Humans; Iran; Klebsiella pneumoniae; Microbial Sensitivity Tests; Plasmids; Quinolones | 2022 |
Genomic Characterization of Ciprofloxacin Resistance in Laboratory-Derived Mutants of
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Genomics; Humans; Microbial Sensitivity Tests; Mutation; Quinolones; Vibrio parahaemolyticus | 2022 |
Phylogenomic Analysis of Salmonella enterica Serovar Indiana ST17, an Emerging Multidrug-Resistant Clone in China.
Topics: Anti-Bacterial Agents; beta-Lactamases; Ceftriaxone; Ciprofloxacin; Clone Cells; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests; Phylogeny; Plasmids; Quinolones; Retrospective Studies; Salmonella enterica; Serogroup | 2022 |
EEM-PARAFAC as a convenient methodology to study fluorescent emerging pollutants degradation: (fluoro)quinolones oxidation in different water matrices.
Topics: Anti-Bacterial Agents; Chlorides; Ciprofloxacin; Coloring Agents; Enrofloxacin; Environmental Pollutants; Ferric Compounds; Humic Substances; Hydrogen Peroxide; Iron; Ofloxacin; Oxolinic Acid; Quinolones; Thiabendazole; Wastewater; Water; Water Pollutants, Chemical | 2022 |
[Ecological Risk Assessment of Quinolones Antibiotics and the Correlation Analysis Between QNs and Physical-Chemical Parameters in Groundwater, Shijiazhuang City].
Topics: Anti-Bacterial Agents; Ciprofloxacin; Environmental Monitoring; Groundwater; Quinolones; Risk Assessment; Water Pollutants, Chemical | 2022 |
Molecular characteristics of fluoroquinolone-resistant Escherichia coli isolated from suckling piglets with colibacillosis.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; beta-Lactamases; Ciprofloxacin; DNA Gyrase; Enrofloxacin; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Norfloxacin; Quinolones; Sulfonamides; Swine | 2022 |
Structure based design and synthesis of 3-(7-nitro-3-oxo-3,4-dihydroquinoxalin-2-yl)propanehydrazide derivatives as novel bacterial DNA-gyrase inhibitors: In-vitro, In-vivo, In-silico and SAR studies.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; DNA Gyrase; DNA, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Quinolones; Staphylococcus aureus; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2022 |
Hotspots sequences of gyrA, gyrB, parC, and parE genes encoded for fluoroquinolones resistance from local Salmonella Typhi strains in Jakarta.
Topics: Amino Acids; Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Nalidixic Acid; Quinolones; Salmonella; Salmonella enterica; Salmonella typhi; Typhoid Fever | 2022 |
[Molecular characteristics of ciprofloxacin-cefotaxime-azithromycin co-resistant
Topics: Animals; Anti-Bacterial Agents; Azithromycin; Cefotaxime; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Foodborne Diseases; Humans; Microbial Sensitivity Tests; Phylogeny; Plasmids; Quinolones; Salmonella; Salmonella enterica; Serogroup | 2022 |
Plasmid-mediated quinolone resistance determinants in clinical bacterial pathogens isolated from the Western Region of Ghana: a cross-sectional study.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Cross-Sectional Studies; Drug Resistance, Bacterial; Escherichia coli; Ghana; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Plasmids; Quinolones | 2022 |
Differential expression of outer membrane proteins and quinolone resistance determining region mutations can lead to ciprofloxacin resistance in Salmonella Typhi.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Membrane Proteins; Microbial Sensitivity Tests; Mutation; Quinolones; Salmonella typhi | 2023 |
Antimicrobial susceptibility pattern and genotypic characterisation of quinolone and ceftriaxone resistant genes among Salmonella typhi from various regions of Pakistan.
Topics: Anti-Bacterial Agents; Ceftriaxone; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Pakistan; Prospective Studies; Quinolones; Salmonella typhi; Typhoid Fever | 2022 |
Cytotoxicity of Tetracyclines in Human Tympanic Membrane Fibroblasts.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Doxycycline; Fibroblasts; Humans; Minocycline; Otitis Externa; Quinolones; Tetracycline; Tympanic Membrane | 2023 |
Plasmid-mediated quinolone resistance genes detected in Ciprofloxacin non-susceptible Escherichia coli and Klebsiella isolated from children under five years at hospital discharge, Kenya.
Topics: Anti-Bacterial Agents; Child; Child, Preschool; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Hospitals; Humans; Kenya; Klebsiella; Microbial Sensitivity Tests; Patient Discharge; Plasmids; Quinolones | 2023 |
Urinary antibiotic concentrations in preschool children from eastern China and health risk assessment.
Topics: Animals; Anti-Bacterial Agents; Azoles; Child, Preschool; China; Chromatography, Liquid; Ciprofloxacin; Humans; Quinolones; Risk Assessment; Tandem Mass Spectrometry | 2023 |
Identification and Genetic Characterization of Conjugative Plasmids Encoding Coresistance to Ciprofloxacin and Cephalosporin in Foodborne
Topics: Anti-Bacterial Agents; Cephalosporins; Ciprofloxacin; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Monobactams; Plasmids; Quinolones; Vibrio | 2023 |
A national study confirms that Escherichia coli from Australian commercial layer hens remain susceptible to critically important antimicrobials.
Topics: Animals; Anti-Bacterial Agents; Australia; Chickens; Ciprofloxacin; Cross-Sectional Studies; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Escherichia coli; Female; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Quinolones | 2023 |
Prevalence and mechanisms of ciprofloxacin resistance in Escherichia coli isolated from hospitalized patients, healthy carriers, and wastewaters in Iran.
Topics: Anti-Bacterial Agents; Child; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Escherichia coli; Humans; Iran; Microbial Sensitivity Tests; Prevalence; Quinolones; Wastewater | 2023 |
Fimbria targeting superparamagnetic iron oxide nanoparticles enhance the antimicrobial and antibiofilm activity of ciprofloxacin against quinolone-resistant E. coli.
Topics: Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Escherichia coli; Escherichia coli Infections; Humans; Magnetic Iron Oxide Nanoparticles; Mannosides; Microbial Sensitivity Tests; Quinolones | 2023 |
Transferable mechanisms of quinolone resistance are more frequent among enterotoxigenic Escherichia coli isolates displaying low-level quinolone resistance.
Topics: Case-Control Studies; Child; Ciprofloxacin; Enterotoxigenic Escherichia coli; Humans; Nalidixic Acid; Quinolones | 2023 |
High prevalence of ciprofloxacin resistance in Escherichia coli isolated from chickens, humans and the environment: An emerging one health issue.
Topics: Amino Acids; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Chickens; Ciprofloxacin; Cross-Sectional Studies; DNA Gyrase; Drug Resistance, Bacterial; Escherichia coli; Humans; Microbial Sensitivity Tests; One Health; Phylogeny; Prevalence; Quinolones | 2023 |