ciprofloxacin and camptothecin

ciprofloxacin has been researched along with camptothecin in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's5 (31.25)29.6817
2010's10 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Busonera, B; Fidecka, S; Giliberti, G; Kedzierska, E; Koziol, AE; La Colla, P; Miroslaw, B; Sanna, G; Stefanska, J; Struga, M; Szulczyk, D1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Abdel-Aziz, M; Abuo-Rahma, Gel-D; Kwon, Y; Park, SE; Sayed, MA1
Babkina, IN; Boldyreva, EV; Burakova, EA; Silnikov, VN; Tikunova, NV; Yarinich, LA; Zakharov, BA1
Bartůněk, P; Horký, P; Konečná, K; Kuneš, J; Pour, M; Sedlák, D; Vacek, J; Voráčová, M1
Cizek, A; Imramovsky, A; Jampilek, J; Kauerova, T; Kollar, P; Michnova, H; Pauk, K; Pospisilova, S; Vinsova, J1
Chen, YM; Fu, HY; Gao, Y; Hai, P; Ma, BJ; Xiao, JF; Xu, LL; Yang, XL; Zhang, SB1
Kato, M; Takada, S; Takayama, S1
Acchini, M; Croera, C; Foti, P; Mineo, E; Neri, MG; Pessina, A; Raimondi, A1
Berti, E; Cerri, A; Croera, C; Foti, P; Neri, MG; Pessina, A; Piccirillo, M; Raimondi, A1
Fabian, I; Halperin, D; Priel, E; Reuveni, D; Shalit, I1
Baracos, VE; Dieleman, LA; Field, CJ; Sawyer, MB; Xue, H1
Higashi, T; Igarashi, T; Iwasaki, H; Kamitani, Y; Kodawara, T; Masada, M; Nakamura, T; Negoro, Y; Tsukamoto, H; Watanabe, K; Yano, R1

Other Studies

16 other study(ies) available for ciprofloxacin and camptothecin

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Disubstituted thiourea derivatives and their activity on CNS: synthesis and biological evaluation.
    European journal of medicinal chemistry, 2012, Volume: 55

    Topics: Animals; Anti-HIV Agents; Anti-Infective Agents; Bacteria; Behavior, Animal; Cell Line, Tumor; Central Nervous System; Chemistry Techniques, Synthetic; Drug Design; Fungi; Humans; Male; Mice; Motor Activity; Thiourea

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Novel N-4-piperazinyl-ciprofloxacin-chalcone hybrids: synthesis, physicochemical properties, anticancer and topoisomerase I and II inhibitory activity.
    European journal of medicinal chemistry, 2013, Volume: 69

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chalcone; Ciprofloxacin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Piperazines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2013
Synthesis and structure-activity relationship of novel 1,4-diazabicyclo[2.2.2]octane derivatives as potent antimicrobial agents.
    European journal of medicinal chemistry, 2015, May-05, Volume: 95

    Topics: Animals; Anti-Bacterial Agents; Bridged Bicyclo Compounds; Cell Line; Chemistry Techniques, Synthetic; Humans; Kinetics; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Octanes; Pseudomonas aeruginosa; Staphylococcus aureus; Structure-Activity Relationship

2015
Nontoxic combretafuranone analogues with high in vitro antibacterial activity.
    European journal of medicinal chemistry, 2018, Jan-01, Volume: 143

    Topics: Anti-Bacterial Agents; Antifungal Agents; Apoptosis; Bacteria; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Fungi; Furans; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2018
In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci.
    Bioorganic & medicinal chemistry letters, 2018, 07-01, Volume: 28, Issue:12

    Topics: Anti-Bacterial Agents; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Enterococcus faecalis; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Vancomycin; Vancomycin-Resistant Enterococci

2018
Prenylated Indole Diterpene Alkaloids from a Mine-Soil-Derived Tolypocladium sp.
    Journal of natural products, 2019, 02-22, Volume: 82, Issue:2

    Topics: Anti-Infective Agents; Cell Line, Tumor; Diterpene Alkaloids; Humans; Hypocreales; Indoles; Magnetic Resonance Spectroscopy; Soil Microbiology

2019
Comparison of lesions induced by intra-articular injections of quinolones and compounds damaging cartilage components in rat femoral condyles.
    Journal of toxicology and environmental health, 1994, Volume: 42, Issue:1

    Topics: Administration, Oral; Animals; Bleomycin; Camptothecin; Cartilage, Articular; Chondroitin Lyases; Ciprofloxacin; Collagenases; Cycloheximide; Ethylmaleimide; Etoposide; Fluorescent Dyes; Hydroxyurea; Injections, Intra-Articular; Iodoacetates; Iodoacetic Acid; Irinotecan; Levofloxacin; Male; Ofloxacin; Papain; Rats; Rats, Sprague-Dawley; Rhodamines; Topoisomerase I Inhibitors

1994
Altered DNA-cleavage activity of topoisomerase II from WEHI-3B leukemia cells with specific resistance to ciprofloxacin.
    Anti-cancer drugs, 2001, Volume: 12, Issue:5

    Topics: Animals; Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Division; Ciprofloxacin; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance, Neoplasm; Leukemia, Myelomonocytic, Acute; Tumor Cells, Cultured

2001
High sensitivity of human epidermal keratinocytes (HaCaT) to topoisomerase inhibitors.
    Cell proliferation, 2001, Volume: 34, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Camptothecin; Cell Division; Cell Line; Cell Survival; Ciprofloxacin; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Humans; Keratinocytes; Macrolides; Topoisomerase I Inhibitors

2001
Quinolones as enhancers of camptothecin-induced cytotoxic and anti-topoisomerase I effects.
    Biochemical pharmacology, 2008, Mar-15, Volume: 75, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Aza Compounds; Camptothecin; Cell Line, Tumor; Ciprofloxacin; DNA; Fluoroquinolones; Humans; Interleukin-8; Moxifloxacin; Quinolines; Topoisomerase I Inhibitors; Vascular Endothelial Growth Factor A

2008
Prophylactic ciprofloxacin treatment prevented high mortality, and modified systemic and intestinal immune function in tumour-bearing rats receiving dose-intensive CPT-11 chemotherapy.
    British journal of cancer, 2009, May-19, Volume: 100, Issue:10

    Topics: Animals; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma; Ciprofloxacin; Colorectal Neoplasms; Diarrhea; Female; Immunity, Mucosal; Intestinal Mucosa; Irinotecan; Lymphatic Metastasis; Neoplasm Transplantation; Rats; Rats, Inbred F344; Spleen; Survival Analysis

2009
The Inhibitory Effect of Ciprofloxacin on the β-Glucuronidase-mediated Deconjugation of the Irinotecan Metabolite SN-38-G.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 118, Issue:5

    Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Ciprofloxacin; Dose-Response Relationship, Drug; Enterohepatic Circulation; Glucuronidase; Glucuronides; Irinotecan; Time Factors

2016