ciprofibrate and phenobarbital

ciprofibrate has been researched along with phenobarbital in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19904 (20.00)18.7374
1990's11 (55.00)18.2507
2000's2 (10.00)29.6817
2010's3 (15.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Lindroos, P; Michalopoulos, GK; Tsai, WH; Zarnegar, R1
Fox, TR; Maher, VM; McCormick, JJ; Schumann, AM; Watanabe, PG; Yano, BL1
Cruise, JL; Michalopoulos, GK; Tsai, WH1
Clark, TD; Glauert, HP1
Brooks, B; Brown, P; Byers, LW; Capdevila, J; Dowell, R; Muirhead, E; Pitcock, JA1
Estabrook, RW; Weiss, RH1
Ioannides, C; Irizar, A1
Lindroos, P; Michalopoulos, GK1
Chen, ZY; Eaton, DL; He, CY; Liu, YF; White, CC2
Guzelian, PS; Kocarek, TA; Schuetz, EG1
Beamand, JA; Charzat, C; Lake, BG; Price, RJ; Renwick, AB; Tredger, JM1
Glauert, HP; Hong, JT; Wilson, MW1
Glauert, HP; Leung, LK1
Novak, RF; Woodcroft, KJ1

Reviews

1 review(s) available for ciprofibrate and phenobarbital

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

19 other study(ies) available for ciprofibrate and phenobarbital

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Plasma levels of HGF in rats treated with tumor promoters.
    Carcinogenesis, 1992, Volume: 13, Issue:1

    Topics: Animals; Carcinogens; Clofibric Acid; Fibric Acids; Growth Substances; Hepatocyte Growth Factor; Hexachlorocyclohexane; Liver Neoplasms; Male; Phenobarbital; Rats; Rats, Inbred F344

1992
Mutational analysis of the H-ras oncogene in spontaneous C57BL/6 x C3H/He mouse liver tumors and tumors induced with genotoxic and nongenotoxic hepatocarcinogens.
    Cancer research, 1990, Jul-01, Volume: 50, Issue:13

    Topics: Animals; Base Sequence; Benzidines; Chloroform; Clofibric Acid; Codon; DNA Mutational Analysis; DNA, Neoplasm; Fibric Acids; Gene Amplification; Genes, ras; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Phenobarbital

1990
Blockade of alpha-1 adrenergic receptor inhibits hepatic DNA synthesis stimulated by tumor promoters.
    Carcinogenesis, 1989, Volume: 10, Issue:1

    Topics: Animals; Carcinogens; Clofibrate; Clofibric Acid; DNA; Fibric Acids; Hexachlorocyclohexane; Liver; Organ Size; Phenobarbital; Prazosin; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha

1989
Lack of initiating activity of the peroxisome proliferator ciprofibrate in two-stage hepatocarcinogenesis.
    Cancer letters, 1989, Volume: 44, Issue:2

    Topics: Animals; Clofibrate; Clofibric Acid; Cocarcinogenesis; Diet; Dose-Response Relationship, Drug; Female; Fibric Acids; Liver; Liver Neoplasms, Experimental; Microbodies; Organ Size; Phenobarbital; Rats; Rats, Inbred Strains

1989
Effect of cytochrome P-450 induction and inhibition on the antihypertensive function of the kidney.
    Transactions of the Association of American Physicians, 1987, Volume: 100

    Topics: Animals; Blood Pressure; Clofibric Acid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Fibric Acids; Hypertension, Renovascular; Hypertrophy; Hypolipidemic Agents; Liver; Male; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Reference Values

1987
The mechanism of cumene hydroperoxide-dependent lipid peroxidation: the function of cytochrome P-450.
    Archives of biochemistry and biophysics, 1986, Nov-15, Volume: 251, Issue:1

    Topics: Animals; Benzene Derivatives; Clofibric Acid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ethanol; Fibric Acids; Heme; In Vitro Techniques; Kinetics; Lipid Metabolism; Lipid Peroxides; Male; Microsomes, Liver; Oxygen; Phenobarbital; Rats; Substrate Specificity

1986
Expression and inducibility of cytochrome P450 proteins belonging to families 2,3 and 4 in the rabbit aorta.
    Biochemical and biophysical research communications, 1995, Aug-24, Volume: 213, Issue:3

    Topics: Animals; Aorta; Arteriosclerosis; Clofibric Acid; Cytochrome P-450 Enzyme System; Enzyme Induction; Fibric Acids; Male; Microsomes; Phenobarbital; Pregnenolone Carbonitrile; Rabbits

1995
Response of phenobarbital- and ciprofibrate-exposed hepatocytes to growth factors in type I collagen gels.
    Carcinogenesis, 1993, Volume: 14, Issue:4

    Topics: Animals; Cell Division; Cells, Cultured; Clofibric Acid; Collagen; DNA; Drug Interactions; Epidermal Growth Factor; Fibric Acids; Fibroblast Growth Factor 1; Hepatocyte Growth Factor; Liver; Male; Phenobarbital; Rats; Rats, Inbred F344

1993
Inhibition of cell proliferation by ciprofibrate in glutathione S-transferase P1-1-positive rat hepatic hyperplastic nodules.
    Cancer research, 1994, May-15, Volume: 54, Issue:10

    Topics: Animals; Cell Division; Clofibric Acid; Cytochrome P-450 Enzyme System; DNA; Fibric Acids; gamma-Glutamyltransferase; Glutathione Transferase; Hyperplasia; Liver; Mice; Phenobarbital; Rats; Rats, Inbred F344

1994
Regulation of phenobarbital-inducible cytochrome P450 2B1/2 mRNA by lovastatin and oxysterols in primary cultures of adult rat hepatocytes.
    Toxicology and applied pharmacology, 1993, Volume: 120, Issue:2

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; Cholesterol; Clofibric Acid; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Fibric Acids; Hydroxycholesterols; Hypolipidemic Agents; L-Lactate Dehydrogenase; Liver; Lovastatin; Male; Mevalonic Acid; Phenobarbital; Rats; Rats, Sprague-Dawley; RNA, Messenger

1993
Induction of cytochrome P450 isoenzymes in cultured precision-cut rat and human liver slices.
    Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:3

    Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Clofenapate; Clofibric Acid; Culture Techniques; Cytochrome P-450 Enzyme System; Enzyme Induction; Fibric Acids; Humans; Isoenzymes; Liver; Male; Microbodies; Phenobarbital; Pyrimidines; Rats; Rats, Sprague-Dawley

1996
Effect of phenobarbital and the peroxisome proliferator ciprofibrate on gamma-Glutamyltranspeptidase activity and leukotriene C4 concentration in cultured rat hepatocytes.
    Journal of biochemical toxicology, 1995, Volume: 10, Issue:5

    Topics: Animals; Biomarkers, Tumor; Cells, Cultured; Clofibric Acid; Fibric Acids; gamma-Glutamyltransferase; Hypolipidemic Agents; Leukotriene C4; Liver; Male; Microbodies; Phenobarbital; Radioimmunoassay; Rats; Rats, Sprague-Dawley

1995
Lack of correlation between hepatic prostaglandin concentrations and DNA synthesis after the administration of phenobarbital and the peroxisome proliferator ciprofibrate in rats.
    Toxicology, 1997, Nov-21, Volume: 123, Issue:1-2

    Topics: Acyl-CoA Oxidase; Animals; Carcinogens; Clofibric Acid; Cytochrome P-450 CYP2B1; Dinoprost; Dinoprostone; DNA; Fibric Acids; Liver; Male; Microbodies; Microsomes, Liver; Oxidoreductases; Phenobarbital; Prostaglandins; Rats; Rats, Sprague-Dawley

1997
Zonal differences in DNA synthesis activity and cytochrome P450 gene expression in livers of male F344 rats treated with five nongenotoxic carcinogens.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 1995, Volume: 14, Issue:2

    Topics: Animals; Blotting, Northern; Bromodeoxyuridine; Carcinogens; Cell Division; Clofibric Acid; Cytochrome P-450 Enzyme System; DNA; Fibric Acids; Gene Expression Regulation, Enzymologic; Liver; Male; Mutagens; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Rats; Rats, Inbred F344; RNA, Messenger

1995
Insulin differentially affects xenobiotic-enhanced, cytochrome P-450 (CYP)2E1, CYP2B, CYP3A, and CYP4A expression in primary cultured rat hepatocytes.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Northern; Cells, Cultured; Clofibric Acid; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Enzyme Induction; Fibric Acids; Insulin; Liver; Male; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenobarbital; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Xenobiotics

1999