ciprofibrate and clofibrate

ciprofibrate has been researched along with clofibrate in 91 studies

Research

Studies (91)

Timeframe	Studies, this research(%)	All Research%
pre-1990	52 (57.14)	18.7374
1990's	23 (25.27)	18.2507
2000's	10 (10.99)	29.6817
2010's	6 (6.59)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Chalmers, DK; Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T; Wielens, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Arnold, A; Beyler, AL; McAuliff, JP; Phillips, DK; Powers, LG	1
Arnold, A; Beyler, AL; McAuliff, MP	1
Baldwin, LA; Calabrese, EJ; Leonard, DA; Ochs, JB	1
Keller, BJ; Thurman, RG; Yamanaka, H	1
Gibson, GG; Lake, BG	1
Gemmell, MA; Giometti, CS; Lalwani, ND; Reddy, JK; Taylor, J; Tollaksen, SL	1
Eacho, PI; Foxworthy, PS; Hoover, DM; White, SL	1
Beaty, MM; Borges, T; Chen, LC; Chow, CK; Clark, TD; Clark, TL; Glauert, HP; Greenwell, WS; Srinivasan, SR; Tatum, V	1
Beije, B; Erixon, K; Nilsson, R; Préat, V; Ramel, C	1
Cherkaoui Malki, M; Corral-Debrinski, M; Latruffe, N; Lone, YC	1
Bardot, O; Cherkaoui Malki, M; Latruffe, N; Lhuguenot, JC	1
Bronfman, M; Hidalgo, PC; Mezzano, D; Morales, MN; Orellana, A	1
Baldwin, LA; Calabrese, EJ; Kostecki, PT; Yang, JH	1
Chow, CK; Glauert, HP; Srinivasan, SR	1
Anders, C; Bonner, F; Gibson, GG; Goldfarb, PS; Makowska, JM	1
Bartles, JR; Fayos, BE; Isoye, ST; Khuon, S; Lin, XH; Nehme, CL; Rao, MS; Reddy, JK; Zhang, LQ	1
Cruise, JL; Michalopoulos, GK; Tsai, WH	1
Barbolt, TA; Bonner, FW; Eason, CT; Henry, DC; Sauerschell, RJ; Spencer, AJ	1
Rajan, A; Rao, MS; Reddy, JK; Subbarao, V; Yeldandi, AV	1
Feller, DR; Kocarek, TA	1
Bernard, N; Cuisinaud, G; Ferry, N; Gardes, E; Labeeuw, M; Pozet, N; Sassard, J; Zech, PY	1
Hellwich, KH; Oelschläger, H; Rothley, D; Schmidt, W	2
Bonner, FW; Gibson, GG; Goldfarb, PS; Makowska, JM	1
Milano, M; Rao, MS; Reddy, JK; Subbarao, V; Yeldandi, AV	1
Kasai, H; Nishimura, S; Okada, Y; Rao, MS; Reddy, JK	1
Alvares, K; Mangino, M; Rao, MS; Reddy, JK; Thangada, S; Usman, MI	1
Angelin, B; Einarsson, K; Ståhlberg, D	1
Beer, D; Coloma, J; Glauert, HP; Goldsworthy, TL; Pitot, HC; Rao, MS; Schwarz, M; Xu, YD	1
Rao, MS; Reddy, JK; Subbarao, V	2
Milano, M; Prasad, JD; Rao, MS; Reddy, JK	1
Dwivedi, RS; Rao, MS; Reddy, JK; Subbarao, V	1
Bonner, FW; Eason, CT; Howells, DD; Pattison, A	1
Marlowe, C; Rao, MS; Reddy, JK; Waddell, WJ	1
Clark, TD; Glauert, HP	1
Agius, L; Alberti, KG; Gerondaes, P	2
Krause, BR; Newton, RS	1
Kokkinakis, DM; Rao, MS; Reddy, JK; Subbarao, V	1
Bonner, FW; Eason, CT; Henry, DC; Howells, DD; Pattison, A; Spencer, AJ	1
Oelschläger, H; Rothley, D; Schmidt, W	1
Agius, L; Bartlett, K; Bhuiyan, AK; Sherratt, HS	1
Bonnefis, MT; Infante, R; Petit, D; Rey, C	1
Bonner, FW; Eason, CT; Howells, DD; Pattison, A; Spencer, AJ	1
Palmer, RH	1
Hunninghake, DB; Peters, JR	1
Carrino, JJ; Goel, SK; Hashimoto, T; Laffler, TG; Lalwani, ND; Nemali, MR; Osumi, T; Reddy, JK; Reddy, MK; Sperbeck, SJ	1
Alvares, K; Lalwani, ND; Parikh, I; Reddy, JK; Reddy, MK; Reddy, MN	1
Evarts, RE; Lalwani, ND; Rao, MS; Reddy, JK; Reddy, MK; Singh, B; Thorgeirsson, S; Usman, MI	1
Foliot, A; Mallet, L; Touchard, D	1
Lalwani, ND; Rao, MS; Reddy, JK; Reddy, MK; Usman, MI	1
Amigo, L; Bronfman, M; Morales, MN	1
Capdevila, J; Estabrook, RW; Falck, JR; Kim, YR; Manna, S; Martin-Wixtrom, C	1
MacDonald, RS; Swan, PB	1
Bakir, R; Chanu, B; Djian, F; Goy-Loeper, J; Rouffy, J	1
Earley, K; Goel, SK; Gupta, RC; Reddy, JK; Singh, B	1
Davidson, JF; Lorimer, AR; Simpson, IA; Walker, ID	1
Lalwani, ND; Qureshi, SA; Rao, MS; Reddy, JK; Reddy, MK; Scarpelli, DG	1
Angelin, B; Einarsson, K; Leijd, B	1
Awasthi, YC; Goel, SK; Reddy, JK; Singh, SV	1
Fahl, WE; Lalwani, ND; Reddy, JK	1
Lalwani, ND; Rao, MS; Reddy, JK; Watanabe, TK	1
Connor, WE; Cook, SF; Illingworth, DR; Olsen, GD; Sexton, GJ; Wendel, HA	1
Olsson, AG; Orö, L	1
Biddlecome, CE; Edelson, J; Koblantz, C; Park, GB	1
Baldwin, LA; Calabrese, EJ; Donohue, M; Kostecki, PT; Leonard, DA	1
Cherkaoui Malki, M; el Kebbaj, MH; Latruffe, N	1
Dujovne, CA; Lozada, A	1
Accatino, L; Amigo, L; Andrade, L; Chianale, J; Gonzalez, S; Nervi, F; Pizarro, M; Rigotti, A; Vollrath, V; Wielandt, AM	1
Galloway, SM; Johnson, TE; Ledwith, BJ; Manam, S; Nichols, WW; Pauley, CJ; Wagner, LK	1
Kockx, M; Kooistra, T; Princen, HM	1
Buhler, DR; Haasch, ML; Henderson, MC	1
Derudas, B; Gervois, PP; Gonzalez, FJ; Kockx, M; Kooistra, T; Peters, JM; Poulain, P; Princen, HM; Staels, B	1
Wallace, KB; Zhou, S	1
Evans, DC; Heavens, R; Jack, A; Meneses-Lorente, G; Surry, DD	1
Barrera, G; Briatore, F; Dianzani, MU; Ferretti, C; Laurora, S; Pizzimenti, S	1
Fujisaki, K; Itoh, Y; Maiguma, T; Makino, K; Oishi, R; Sasaguri, T; Takahashi-Yanaga, F; Teshima, D	1
Barrera, G; Briatore, F; Dianzani, MU; Ferretti, C; Fraioli, A; Laurora, S; Maggio, M; Pizzimenti, S; Reffo, P	1
Ammerschlaeger, M; Beigel, J; Klein, KU; Mueller, SO	1
Baldwin, GS; Ford, J; Lachal, S; Shulkes, A	1

Reviews

4 review(s) available for ciprofibrate and clofibrate

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
Effects of fibric acid derivatives on biliary lipid composition. The American journal of medicine, 1987, Nov-27, Volume: 83, Issue:5B Topics: Bezafibrate; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Double-Blind Method; Female; Fenofibrate; Fibric Acids; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Male; Propionates; Random Allocation	1987
Effect of fibric acid derivatives on blood lipid and lipoprotein levels. The American journal of medicine, 1987, Nov-27, Volume: 83, Issue:5B Topics: Anticholesteremic Agents; Bezafibrate; Clofibrate; Clofibric Acid; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipoproteinemia Type II; Lipids; Lipoproteins; Pentanoic Acids	1987
Drug interactions with fibric acids. Pharmacology & therapeutics, 1994, Volume: 63, Issue:2 Topics: Anticoagulants; Bezafibrate; Clofibrate; Clofibric Acid; Contraceptives, Oral; Coronary Disease; Drug Interactions; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Lipids	1994

Trials

3 trial(s) available for ciprofibrate and clofibrate

Article	Year
Effects of fibric acid derivatives on biliary lipid composition. The American journal of medicine, 1987, Nov-27, Volume: 83, Issue:5B Topics: Bezafibrate; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Double-Blind Method; Female; Fenofibrate; Fibric Acids; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Male; Propionates; Random Allocation	1987
Comparative evaluation of the effects of ciprofibrate and fenofibrate on lipids, lipoproteins and apoproteins A and B. Atherosclerosis, 1985, Volume: 54, Issue:3 Topics: Adult; Apolipoproteins A; Apolipoproteins B; Clofibrate; Clofibric Acid; Drug Evaluation; Female; Fenofibrate; Fibric Acids; Humans; Hyperlipoproteinemia Type II; Lipids; Lipoproteins; Male; Propionates; Time Factors	1985
Ciprofibrate in the therapy of type II hypercholesterolemia. A double-blind trial. Atherosclerosis, 1982, Volume: 44, Issue:2 Topics: Adult; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Double-Blind Method; Female; Fibric Acids; Humans; Hyperlipoproteinemia Type II; Male	1982

Other Studies

85 other study(ies) available for ciprofibrate and clofibrate

Article	Year
Identifying off-target effects and hidden phenotypes of drugs in human cells. Nature chemical biology, 2006, Volume: 2, Issue:6 Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship	2006
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Probing the fibrate binding specificity of rat liver fatty acid binding protein. Journal of medicinal chemistry, 2009, Sep-10, Volume: 52, Issue:17 Topics: Animals; Binding Sites; Carboxylic Acids; Clofibric Acid; Esters; Fatty Acid-Binding Proteins; Fenofibrate; Hypolipidemic Agents; Ligands; Liver; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Rats; Spectrometry, Fluorescence; Substrate Specificity; Temperature; Thermodynamics	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
The results of animal studies with ciprofibrate, a new orally effective hypolipidemic drug. Atherosclerosis, 1979, Volume: 32, Issue:2 Topics: Administration, Oral; Animals; Anticholesteremic Agents; Cholesterol; Clofibrate; Cyclopropanes; Drug Evaluation, Preclinical; Fibric Acids; Hyperlipidemias; Hypolipidemic Agents; Male; Rats; Triglycerides	1979
Metabolic effects of a new hypolipidemic agent, ciprofibrate. Journal of pharmaceutical sciences, 1979, Volume: 68, Issue:12 Topics: Animals; Cholesterol; Clofibrate; Clofibric Acid; Fatty Acids, Nonesterified; Fibric Acids; Hypolipidemic Agents; Lipase; Norepinephrine; Polyethylene Glycols; Rats	1979
Effects of joint exposures to selected peroxisome proliferators on hepatic acyl-CoA oxidase activity in male B6C3F1 mice. Human & experimental toxicology, 1992, Volume: 11, Issue:2 Topics: Acyl-CoA Oxidase; Animals; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Fibric Acids; Hypolipidemic Agents; Liver; Male; Mice; Mice, Inbred Strains; Microbodies; Oxidoreductases	1992
Inhibition of mitochondrial respiration and oxygen-dependent hepatotoxicity by six structurally dissimilar peroxisomal proliferating agents. Toxicology, 1992, Volume: 71, Issue:1-2 Topics: Animals; Aspirin; Cell Division; Clofibrate; Clofibric Acid; Dose-Response Relationship, Drug; Female; Fibric Acids; Hypolipidemic Agents; L-Lactate Dehydrogenase; Microbodies; Mitochondria, Liver; Oxygen Consumption; Rats; Rats, Inbred Strains; Trypan Blue; Valproic Acid	1992
Induction protocols for the cytochrome P450IVA subfamily in animals and primary hepatocyte cultures. Methods in enzymology, 1991, Volume: 206 Topics: Animals; Cells, Cultured; Clofibrate; Clofibric Acid; Culture Techniques; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Enzyme Induction; Fibric Acids; Genetic Techniques; Isoenzymes; Liver; Rats; Rats, Inbred Strains; RNA, Messenger; Species Specificity; Transcription, Genetic	1991
Quantitative changes in sets of proteins as markers of biological response. Progress in clinical and biological research, 1991, Volume: 372 Topics: Animals; Biomarkers; Carcinogens; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Electrophoresis, Gel, Two-Dimensional; Fibric Acids; Liver; Liver Neoplasms, Experimental; Male; Mice; Proteins; Pyrimidines	1991
Effect of ciprofibrate, bezafibrate, and LY171883 on peroxisomal beta-oxidation in cultured rat, dog, and rhesus monkey hepatocytes. Toxicology and applied pharmacology, 1990, Volume: 104, Issue:3 Topics: Acetophenones; Animals; Autacoids; Azoles; Bezafibrate; Cells, Cultured; Clofibrate; Clofibric Acid; Dexamethasone; Dogs; Dose-Response Relationship, Drug; Female; Fibric Acids; Glucagon; Hypolipidemic Agents; In Vitro Techniques; Liver; Male; Microbodies; Microscopy, Electron; NAD; Oxidation-Reduction; Rats; Tetrazoles; Tyrosine Transaminase	1990
Effect of dietary vitamin E on the development of altered hepatic foci and hepatic tumors induced by the peroxisome proliferator ciprofibrate. Journal of cancer research and clinical oncology, 1990, Volume: 116, Issue:4 Topics: Adenosine Triphosphatases; Animals; Clofibrate; Clofibric Acid; Drug Synergism; Female; Fibric Acids; gamma-Glutamyltransferase; Glucose-6-Phosphatase; Liver; Liver Neoplasms, Experimental; Rats; Rats, Inbred Strains; Vitamin E	1990
On the mechanism of the hepatocarcinogenicity of peroxisome proliferators. Chemico-biological interactions, 1991, Volume: 78, Issue:2 Topics: Animals; Caprylates; Carcinogens; Clofibrate; Clofibric Acid; DNA; DNA Damage; DNA Repair; Fibric Acids; Fluorocarbons; Liver; Liver Neoplasms; Male; Microbodies; Micronucleus Tests; Mutagenicity Tests; Nafenopin; Radiation, Ionizing; Rats; Rats, Inbred Strains; S Phase	1991
Differential proto-oncogene mRNA induction from rats treated with peroxisome proliferators. Biochemical and biophysical research communications, 1990, Dec-31, Volume: 173, Issue:3 Topics: Acyl-CoA Oxidase; Animals; Clofibrate; Clofibric Acid; Fibric Acids; Gene Expression Regulation; Genes, myc; Genes, ras; Hypolipidemic Agents; Kidney; Liver; Male; Microbodies; Organ Specificity; Oxidoreductases; Proto-Oncogenes; Rats; Rats, Inbred F344; RNA, Messenger	1990
Expression of liver peroxisomal proteins as compared to other organelle marker enzymes in rats treated with hypolipidemic agents. Biology of the cell, 1990, Volume: 69, Issue:2 Topics: Animals; Base Sequence; Cell Fractionation; Clofibrate; Clofibric Acid; DNA Probes; Fibric Acids; Hypolipidemic Agents; Immunoblotting; Liver; Male; Microbodies; Molecular Sequence Data; Organelles; Rats; Rats, Inbred F344; Rats, Inbred Strains; RNA, Messenger	1990
Palmitoyl-CoA and the acyl-CoA thioester of the carcinogenic peroxisome-proliferator ciprofibrate potentiate diacylglycerol-activated protein kinase C by decreasing the phosphatidylserine requirement of the enzyme. European journal of biochemistry, 1990, May-31, Volume: 190, Issue:1 Topics: Acyl Coenzyme A; Animals; Blood Platelets; Brain; Calcium; Clofibrate; Clofibric Acid; Cocarcinogenesis; Diglycerides; Drug Synergism; Enzyme Activation; Fibric Acids; Glycerides; Histones; Humans; Microbodies; Palmitoyl Coenzyme A; Phosphatidylserines; Phosphorylation; Protein Kinase C; Rats	1990
Induction of peroxisome proliferation in rainbow trout exposed to ciprofibrate. Toxicology and applied pharmacology, 1990, Volume: 104, Issue:3 Topics: Acyl-CoA Oxidase; Analysis of Variance; Animals; Blotting, Western; Body Weight; Catalase; Clofibrate; Clofibric Acid; Dose-Response Relationship, Drug; Fibric Acids; Hypolipidemic Agents; Liver; Microbodies; Organ Size; Oxidoreductases; Peptide Biosynthesis; Peptides; Time Factors; Trout	1990
Effect of the peroxisome proliferator ciprofibrate on hepatic DNA synthesis and hepatic composition following partial hepatectomy in rats. Toxicology, 1990, Volume: 62, Issue:3 Topics: Administration, Oral; Animals; Body Weight; Clofibrate; Clofibric Acid; DNA; Female; Fibric Acids; Hepatectomy; Hypolipidemic Agents; Liver; Organ Size; Rats; Rats, Inbred Strains; Vitamin E	1990
Characterization of the hepatic responses to the short-term administration of ciprofibrate in several rat strain. Co-induction of microsomal cytochrome P-450 IVA1 and peroxisome proliferation. Biochemical pharmacology, 1990, Sep-01, Volume: 40, Issue:5 Topics: Administration, Oral; Animals; Body Weight; Cell Division; Clofibrate; Clofibric Acid; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Fibric Acids; Glutathione Peroxidase; Hypolipidemic Agents; Male; Microbodies; Microsomes, Liver; Organ Size; Oxidoreductases; Oxidoreductases, N-Demethylating; Rats; Rats, Gunn; Rats, Inbred F344; Rats, Inbred Strains; Species Specificity	1990
Peroxisome proliferator-induced alterations in the expression and modification of rat hepatocyte plasma membrane proteins. Cancer research, 1990, Feb-01, Volume: 50, Issue:3 Topics: Antibodies, Monoclonal; Asialoglycoprotein Receptor; Blotting, Western; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; ErbB Receptors; Fibric Acids; Fluorescent Antibody Technique; Isoelectric Point; Liver; Membrane Glycoproteins; Microbodies; Pyrimidines; Receptors, Immunologic; Sialoglycoproteins	1990
Blockade of alpha-1 adrenergic receptor inhibits hepatic DNA synthesis stimulated by tumor promoters. Carcinogenesis, 1989, Volume: 10, Issue:1 Topics: Animals; Carcinogens; Clofibrate; Clofibric Acid; DNA; Fibric Acids; Hexachlorocyclohexane; Liver; Organ Size; Phenobarbital; Prazosin; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha	1989
Gastric morphological changes including carcinoid tumors in animals treated with a potent hypolipidemic agent, ciprofibrate. Toxicologic pathology, 1989, Volume: 17, Issue:1 Pt 1 Topics: Animals; Callitrichinae; Carcinoid Tumor; Clofibrate; Clofibric Acid; Fibric Acids; Gastric Mucosa; Gastrins; Hypolipidemic Agents; Male; Mice; Microscopy, Electron; Rats; Rats, Inbred F344; Stomach Neoplasms	1989
gamma-Glutamyltranspeptidase-negative phenotypic property of preneoplastic and neoplastic liver lesions induced by ciprofibrate does not change following 2-acetylaminofluorene administration. Carcinogenesis, 1989, Volume: 10, Issue:4 Topics: 2-Acetylaminofluorene; Animals; Clofibrate; Clofibric Acid; Fibric Acids; gamma-Glutamyltransferase; Liver; Liver Neoplasms; Precancerous Conditions; Rats; Rats, Inbred F344	1989
Quantitative assessment of enzyme induction by peroxisome proliferators and application to determination of effects on triglyceride biosynthesis in primary cultures of rat hepatocytes. Biochemical pharmacology, 1989, Dec-01, Volume: 38, Issue:23 Topics: Acyl-CoA Oxidase; Animals; Cells, Cultured; Clofibrate; Clofibric Acid; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Fibric Acids; Gemfibrozil; Kinetics; Liver; Microbodies; Mixed Function Oxygenases; Oxidoreductases; Rats; Triglycerides	1989
The influence of renal insufficiency and haemodialysis on the kinetics of ciprofibrate. British journal of clinical pharmacology, 1989, Volume: 28, Issue:6 Topics: Adult; Aged; Clofibrate; Clofibric Acid; Female; Fibric Acids; Humans; Hypolipidemic Agents; Kidney Diseases; Male; Middle Aged; Renal Dialysis	1989
[The pharmacokinetics of hypolipemic agents. 6. Is 2-(4-(2,2-dichlorocyclopropyl)-phenoxy)-propane a metabolite of the hypolipemic ciprofibrate?]. Archiv der Pharmazie, 1989, Volume: 322, Issue:10 Topics: Chromatography, High Pressure Liquid; Clofibrate; Clofibric Acid; Fibric Acids; Humans; Hypolipidemic Agents	1989
Species differences in the hepatic response to a potent peroxisome proliferator. Biochemical Society transactions, 1989, Volume: 17, Issue:6 Topics: Animals; Clofibrate; Clofibric Acid; Cytochrome P-450 Enzyme System; Fibric Acids; Guinea Pigs; Hypolipidemic Agents; Lauric Acids; Liver; Male; Microbodies; Rats; Rats, Inbred Strains; RNA, Messenger; Species Specificity	1989
Evaluation of liver cell proliferation during ciprofibrate-induced hepatocarcinogenesis. Cancer letters, 1989, Sep-15, Volume: 47, Issue:1-2 Topics: Animals; Cell Division; Clofibrate; Clofibric Acid; DNA; Ethoxyquin; Fibric Acids; Liver; Liver Neoplasms, Experimental; Male; Microbodies; Rats; Rats, Inbred F344	1989
Formation of 8-hydroxydeoxyguanosine in liver DNA of rats following long-term exposure to a peroxisome proliferator. Cancer research, 1989, May-15, Volume: 49, Issue:10 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cell Division; Clofibrate; Clofibric Acid; Deoxyguanosine; DNA; Fibric Acids; Liver; Liver Neoplasms, Experimental; Male; Microbodies; Rats; Rats, Inbred F344	1989
An in vitro demonstration of peroxisome proliferation and increase in peroxisomal beta-oxidation system mRNAs in cultured rat hepatocytes treated with ciprofibrate. FEBS letters, 1989, Jul-03, Volume: 250, Issue:2 Topics: Animals; Blotting, Northern; Catalase; Cells, Cultured; Clofibrate; Clofibric Acid; Cycloheximide; Fibric Acids; Hypolipidemic Agents; Liver; Male; Microbodies; Oxidation-Reduction; Protein Biosynthesis; Proteins; Rats; Rats, Inbred F344; RNA, Messenger	1989
[The pharmacokinetics of antilipemic agents. 5. Is 2-(4-hydroxyphenoxy)-2-methylpropionic acid a metabolite of the antilipemic ciprofibrate?]. Archiv der Pharmazie, 1989, Volume: 322, Issue:6 Topics: Clofibrate; Clofibric Acid; Fibric Acids; Humans; Hypolipidemic Agents	1989
Effects of treatment with clofibrate, bezafibrate, and ciprofibrate on the metabolism of cholesterol in rat liver microsomes. Journal of lipid research, 1989, Volume: 30, Issue:7 Topics: Animals; Bezafibrate; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Clofibrate; Clofibric Acid; Fibric Acids; Hydroxymethylglutaryl CoA Reductases; Hypolipidemic Agents; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Sterol O-Acyltransferase	1989
Induction of altered hepatic foci in rats by the administration of hypolipidemic peroxisome proliferators alone or following a single dose of diethylnitrosamine. Cancer research, 1986, Volume: 46, Issue:9 Topics: Adenosine Triphosphatases; Animals; Clofibrate; Clofibric Acid; Diethylnitrosamine; Drug Administration Schedule; Fibric Acids; gamma-Glutamyltransferase; Glucose-6-Phosphatase; Hepatectomy; Immunologic Techniques; Liver; Microbodies; Pyrimidines; Rats; Time Factors	1986
Peroxisome proliferator-induced hepatocarcinogenesis: histochemical analysis of ciprofibrate-induced preneoplastic and neoplastic lesions for gamma-glutamyl transpeptidase activity. Journal of the National Cancer Institute, 1986, Volume: 77, Issue:4 Topics: Animals; Clofibrate; Clofibric Acid; Fibric Acids; gamma-Glutamyltransferase; Histocytochemistry; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Inbred F344	1986
Absence of gamma-glutamyltranspeptidase activity in lung metastasis in rats with hepatocellular carcinomas induced by ciprofibrate, a peroxisome proliferator. Cancer letters, 1987, Volume: 38, Issue:1-2 Topics: Animals; Cell Division; Clofibrate; Clofibric Acid; Fibric Acids; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Microbodies; Rats; Rats, Inbred F344	1987
Induction of peroxisome proliferation and hepatic tumours in C57BL/6N mice by ciprofibrate, a hypolipidaemic compound. British journal of cancer, 1988, Volume: 58, Issue:1 Topics: Adenoma; Animals; Clofibrate; Clofibric Acid; Fibric Acids; gamma-Glutamyltransferase; Hypolipidemic Agents; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Microbodies	1988
The effect of ciprofibrate on gastric secretion in the rat. The Journal of pharmacy and pharmacology, 1988, Volume: 40, Issue:7 Topics: Animals; Clofibrate; Clofibric Acid; Dose-Response Relationship, Drug; Female; Fibric Acids; Gastric Mucosa; Hypolipidemic Agents; Male; Mice; Rats; Rats, Inbred F344; Reference Values	1988
In vivo distribution of a carcinogenic hepatic peroxisome proliferator: whole-body autoradiography of [14C]ciprofibrate in the mouse. Carcinogenesis, 1989, Volume: 10, Issue:1 Topics: Administration, Oral; Animals; Autoradiography; Carcinogens; Clofibrate; Clofibric Acid; Fibric Acids; Male; Mice; Time Factors; Tissue Distribution	1989
Lack of initiating activity of the peroxisome proliferator ciprofibrate in two-stage hepatocarcinogenesis. Cancer letters, 1989, Volume: 44, Issue:2 Topics: Animals; Clofibrate; Clofibric Acid; Cocarcinogenesis; Diet; Dose-Response Relationship, Drug; Female; Fibric Acids; Liver; Liver Neoplasms, Experimental; Microbodies; Organ Size; Phenobarbital; Rats; Rats, Inbred Strains	1989
Fatty acid metabolism in hepatocytes cultured with hypolipidaemic drugs. Role of carnitine. The Biochemical journal, 1988, Jul-01, Volume: 253, Issue:1 Topics: Animals; Bezafibrate; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Cells, Cultured; Clofibrate; Clofibric Acid; Fatty Acids; Fibric Acids; Glucagon; Humans; Hypolipidemic Agents; Insulin; Liver; Male; Rats; Rats, Inbred Strains	1988
Gemfibrozil increases both apo A-I and apo E concentrations. Comparison to other lipid regulators in cholesterol-fed rats. Atherosclerosis, 1986, Volume: 59, Issue:1 Topics: Animals; Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins E; Bezafibrate; Cholesterol, Dietary; Cholesterol, HDL; Clofibrate; Clofibric Acid; Fenofibrate; Fibric Acids; Gemfibrozil; Male; Pentanoic Acids; Rats; Rats, Inbred Strains; Valerates	1986
Peroxisome proliferator-induced hepatocarcinogenesis: levels of activating and detoxifying enzymes in hepatocellular carcinomas induced by ciprofibrate. Carcinogenesis, 1987, Volume: 8, Issue:1 Topics: Animals; Clofibrate; Clofibric Acid; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Epoxide Hydrolases; Fibric Acids; Glucuronosyltransferase; Liver Neoplasms, Experimental; Male; Microbodies; Microsomes, Liver; Rats; Rats, Inbred F344; Sulfurtransferases	1987
Species variation in gastric toxicity following chronic administration of ciprofibrate to rat, mouse, and marmoset. Toxicology and applied pharmacology, 1988, Sep-15, Volume: 95, Issue:2 Topics: Animals; Callitrichinae; Clofibrate; Clofibric Acid; Fibric Acids; Gastrins; Male; Mice; Rats; Rats, Inbred F344; Species Specificity; Stomach	1988
[Pharmacokinetics of antilipemic agents. 4. Biotransformation of the antilipemic agent ciprofibrate (2-(4-(2,2-dichlorcyclopropyl)-phenoxy)-2-methylpropionic acid)]. Archiv der Pharmazie, 1988, Volume: 321, Issue:6 Topics: Biotransformation; Chromatography, High Pressure Liquid; Clofibrate; Clofibric Acid; Fibric Acids; Humans; Hypolipidemic Agents	1988
Effects of ciprofibrate and 2-[5-(4-chlorophenyl)pentyl]oxirane-2-carboxylate (POCA) on the distribution of carnitine and CoA and their acyl-esters and on enzyme activities in rats. Relation between hepatic carnitine concentration and carnitine acetyltran The Biochemical journal, 1988, Jul-15, Volume: 253, Issue:2 Topics: Acyl Coenzyme A; Animals; Carnitine; Carnitine O-Acetyltransferase; Cells, Cultured; Clofibrate; Clofibric Acid; Coenzyme A; Epoxy Compounds; Ethers, Cyclic; Fibric Acids; Hypoglycemic Agents; Hypolipidemic Agents; Liver; Male; Rats; Rats, Inbred Strains; Tissue Distribution	1988
Effects of ciprofibrate and fenofibrate on liver lipids and lipoprotein synthesis in normo- and hyperlipidemic rats. Atherosclerosis, 1988, Volume: 74, Issue:3 Topics: Animals; Apolipoproteins; Cholesterol; Clofibrate; Clofibric Acid; Fenofibrate; Fibric Acids; Hyperlipidemias; Lipids; Lipoproteins; Liver; Male; Propionates; Rats; Rats, Inbred Strains	1988
Assessment of gastric antisecretory effects of phenoxyisobutyrate derivatives in the rat and the mouse. Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:9 Topics: Administration, Oral; Animals; Bezafibrate; Carcinoid Tumor; Clofibrate; Clofibric Acid; Fibric Acids; Gastric Juice; Male; Mice; Mice, Inbred Strains; Rats; Rats, Inbred F344; Species Specificity; Stomach Neoplasms; Time Factors	1988
Interactions of inhibitors of carnitine palmitoyltransferase I and fibrates in cultured hepatocytes. The Biochemical journal, 1988, Jul-01, Volume: 253, Issue:1 Topics: Acyltransferases; Animals; Bezafibrate; Carnitine O-Palmitoyltransferase; Cells, Cultured; Clofibrate; Clofibric Acid; Epoxy Compounds; Ethers, Cyclic; Fatty Acids; Fibric Acids; Isoenzymes; Liver; Male; Rats; Rats, Inbred Strains; Time Factors; Triglycerides	1988
Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators. Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:6 Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acyl-CoA Oxidase; Animals; Catalase; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Enoyl-CoA Hydratase; Fibric Acids; Hydro-Lyases; Immunoelectrophoresis; Isomerases; Liver; Male; Microbodies; Multienzyme Complexes; Oxidoreductases; Peroxisomal Bifunctional Enzyme; Rats; Rats, Inbred F344; RNA, Messenger; Transcription, Genetic	1986
Peroxisome proliferator-binding protein: identification and partial characterization of nafenopin-, clofibric acid-, and ciprofibrate-binding proteins from rat liver. Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:15 Topics: Animals; Carrier Proteins; Clofibrate; Clofibric Acid; Fibric Acids; Intracellular Signaling Peptides and Proteins; Liver; Male; Molecular Weight; Nafenopin; Propionates; Rats; Rats, Inbred F344	1987
Induction of peroxisome proliferation in hepatocytes transplanted into the anterior chamber of the eye. A model system for the evaluation of xenobiotic-induced effects. The American journal of pathology, 1986, Volume: 124, Issue:3 Topics: Animals; Anterior Chamber; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Fibric Acids; Fluorescent Antibody Technique; Liver; Liver Transplantation; Male; Microbodies; Phthalic Acids; Rats; Rats, Inbred F344	1986
Inhibition of liver glutathione S-transferase activity in rats by hypolipidemic drugs related or unrelated to clofibrate. Biochemical pharmacology, 1986, May-15, Volume: 35, Issue:10 Topics: Animals; Bile; Cell Division; Clofibrate; Clofibric Acid; Fibric Acids; Glutathione Transferase; Hypolipidemic Agents; Liver; Male; Microbodies; Rats; Rats, Inbred Strains; Sulfobromophthalein	1986
Comparison of hepatic peroxisome proliferative effect and its implication for hepatocarcinogenicity of phthalate esters, di(2-ethylhexyl) phthalate, and di(2-ethylhexyl) adipate with a hypolipidemic drug. Environmental health perspectives, 1986, Volume: 65 Topics: Adipates; Animals; Catalase; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Fibric Acids; Liver; Liver Neoplasms, Experimental; Microbodies; Microscopy, Electron; Oxidation-Reduction; Phthalic Acids; Rats; Structure-Activity Relationship	1986
Increased resistance of peroxisome proliferator-induced hepatic lesions to iron overload in rats. Cancer letters, 1986, Volume: 32, Issue:1 Topics: Animals; Cell Division; Clofibrate; Clofibric Acid; Fibric Acids; Iron; Liver; Liver Neoplasms, Experimental; Male; Microbodies; Precancerous Conditions; Pyrimidines; Rats; Rats, Inbred F344	1986
Activation of hypolipidaemic drugs to acyl-coenzyme A thioesters. The Biochemical journal, 1986, Nov-01, Volume: 239, Issue:3 Topics: Acyl Coenzyme A; Animals; Chromatography, High Pressure Liquid; Clofibrate; Clofibric Acid; Coenzyme A Ligases; Fibric Acids; Hydrolysis; Male; Microsomes, Liver; Nafenopin; Propionates; Rats; Rats, Inbred Strains; Repressor Proteins; Saccharomyces cerevisiae Proteins; Spectrophotometry, Ultraviolet	1986
Influence of a fibric acid type of hypolipidemic agent on the oxidative metabolism of arachidonic acid by liver microsomal cytochrome P-450. Archives of biochemistry and biophysics, 1985, Nov-15, Volume: 243, Issue:1 Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Benzphetamine; Chromatography, High Pressure Liquid; Clofibrate; Clofibric Acid; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Fibric Acids; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Hypolipidemic Agents; Lauric Acids; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains	1985
The effect of three hypolipidemic drugs on catalase activity and peroxisomal and mitochondrial palmitate oxidation in rat cardiac and skeletal muscle. Biochimica et biophysica acta, 1986, Feb-19, Volume: 880, Issue:2-3 Topics: Animals; Body Weight; Catalase; Clofibrate; Clofibric Acid; Fibric Acids; Hypolipidemic Agents; Male; Microbodies; Mitochondria, Heart; Mitochondria, Muscle; Muscles; Myocardium; Nafenopin; Oxidation-Reduction; Palmitates; Palmitic Acids; Rats; Rats, Inbred Strains	1986
32P-postlabeling analysis of peroxisome proliferator-DNA adduct formation in rat liver in vivo and hepatocytes in vitro. Carcinogenesis, 1985, Volume: 6, Issue:6 Topics: Animals; Anticholesteremic Agents; Carcinogens; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; DNA; Fibric Acids; Hypolipidemic Agents; In Vitro Techniques; Liver; Liver Neoplasms; Male; Microbodies; Phosphorus Radioisotopes; Pyrimidines; Rats	1985
Effect of Ciprofibrate on platelet aggregation and fibrinolysis in patients with hypercholesterolaemia. Thrombosis and haemostasis, 1985, Aug-30, Volume: 54, Issue:2 Topics: Adult; Alkaline Phosphatase; Cholesterol; Clofibrate; Clofibric Acid; Fibric Acids; Fibrinogen; Fibrinolysis; Humans; Hypercholesterolemia; Male; Middle Aged; Platelet Aggregation; Platelet Count	1985
Induction and origin of hepatocytes in rat pancreas. The Journal of cell biology, 1984, Volume: 98, Issue:6 Topics: Animals; Clofibrate; Clofibric Acid; Fibric Acids; Hypolipidemic Agents; Liver; Male; Microscopy, Electron; Organ Specificity; Pancreas; Rats; Rats, Inbred F344; Staining and Labeling	1984
Effect of ciprofibrate treatment on biliary lipids in patients with hyperlipoproteinaemia. European journal of clinical investigation, 1984, Volume: 14, Issue:1 Topics: Adult; Aged; Bile; Bile Acids and Salts; Cholesterol; Clofibrate; Clofibric Acid; Female; Fibric Acids; Humans; Hyperlipoproteinemias; Lipids; Male; Middle Aged; Phospholipids; Triglycerides	1984
Irreversible inhibition of hepatic glutathione S-transferase by ciprofibrate, a peroxisome proliferator. Biochemical and biophysical research communications, 1984, Sep-28, Volume: 123, Issue:3 Topics: Animals; Clofibrate; Clofibric Acid; Ethoxyquin; Fibric Acids; Glutathione Transferase; Kinetics; Liver; Macromolecular Substances; Male; Microbodies; Rats; Rats, Inbred F344	1984
Detection of a nafenopin-binding protein in rat liver cytosol associated with the induction of peroxisome proliferation by hypolipidemic compounds. Biochemical and biophysical research communications, 1983, Oct-31, Volume: 116, Issue:2 Topics: Animals; Carrier Proteins; Clofibrate; Clofibric Acid; Cytosol; Enzyme Induction; Fibric Acids; Kidney Cortex; Liver; Male; Microbodies; Nafenopin; Propionates; Rats; Rats, Inbred F344	1983
Inhibitory effect of antioxidants ethoxyquin and 2(3)-tert-butyl-4-hydroxyanisole on hepatic tumorigenesis in rats fed ciprofibrate, a peroxisome proliferator. Cancer research, 1984, Volume: 44, Issue:3 Topics: Animals; Anisoles; Antioxidants; Body Weight; Butylated Hydroxyanisole; Carcinogens; Clofibrate; Clofibric Acid; Drug Antagonism; Ethoxyquin; Fibric Acids; Hypolipidemic Agents; Liver Neoplasms; Male; Microbodies; Quinolines; Rats; Rats, Inbred F344	1984
Dose-response study of the effect of ciprofibrate on serum lipoprotein concentrations in hyperlipoproteinaemia. Atherosclerosis, 1982, Volume: 42, Issue:2-3 Topics: Alanine Transaminase; Aspartate Aminotransferases; Blood Sedimentation; Body Weight; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Clofibrate; Clofibric Acid; Dose-Response Relationship, Drug; Fibric Acids; Follow-Up Studies; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hyperlipoproteinemias; Hypolipidemic Agents; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Triglycerides	1982
Determination of ciprofibrate in human plasma by high-performance liquid chromatography. Journal of chromatography, 1982, Feb-12, Volume: 227, Issue:2 Topics: Animals; Chromatography, High Pressure Liquid; Clofibrate; Clofibric Acid; Computers; Fibric Acids; Humans; Rats; Reference Values	1982
Effect of hypolipidemic drugs gemfibrozil, ciprofibrate, and clofibric acid on peroxisomal beta-oxidation in primary cultures of rainbow trout hepatocytes. Ecotoxicology and environmental safety, 1993, Volume: 26, Issue:2 Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acyl-CoA Oxidase; Animals; Cells, Cultured; Clofibrate; Clofibric Acid; Cytochrome P-450 Enzyme System; Enoyl-CoA Hydratase; Enzyme Activation; Fibric Acids; Gemfibrozil; Hypolipidemic Agents; Isomerases; Liver; Male; Microbodies; Multienzyme Complexes; Oncorhynchus mykiss; Oxidation-Reduction; Oxidoreductases; Peroxisomal Bifunctional Enzyme	1993
Effect of peroxisomes proliferators and hypolipemic agents on mitochondrial inner membrane linked D-3-hydroxybutyrate dehydrogenase (BDH). Biochemistry and molecular biology international, 1995, Volume: 35, Issue:1 Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Binding, Competitive; Clofibrate; Clofibric Acid; Fenofibrate; Fibric Acids; Hydroxybutyrate Dehydrogenase; Hypolipidemic Agents; In Vitro Techniques; Intracellular Membranes; Male; Microbodies; Mitochondria; Mitochondria, Liver; Phospholipids; Rats; Rats, Wistar; Tetrahymena pyriformis	1995
Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse. The Biochemical journal, 1996, Mar-15, Volume: 314 ( Pt 3) Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Bezafibrate; Bile; Bile Canaliculi; Clofibrate; Clofibric Acid; DNA Primers; Drug Resistance, Multiple; Fenofibrate; Fibric Acids; Gemfibrozil; Gene Expression; Hypolipidemic Agents; Liver; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Multigene Family; Phospholipids; RNA, Messenger; RNA, Ribosomal, 18S	1996
Growth regulation by peroxisome proliferators: opposing activities in early and late G1. Cancer research, 1996, Jul-15, Volume: 56, Issue:14 Topics: Animals; Bezafibrate; Carcinogens; Cell Cycle; Cell Line; Clofibrate; Clofibric Acid; DNA; Fibric Acids; Gene Expression Regulation; Genes, Immediate-Early; Growth Substances; Mice; Microbodies; Pyrimidines; Signal Transduction; Time Factors; Transcriptional Activation	1996
Fibrate-modulated expression of fibrinogen, plasminogen activator inhibitor-1 and apolipoprotein A-I in cultured cynomolgus monkey hepatocytes -- role of the peroxisome proliferator-activated receptor-alpha. Thrombosis and haemostasis, 1998, Volume: 80, Issue:6 Topics: 5,8,11,14-Eicosatetraynoic Acid; Alitretinoin; Animals; Apolipoprotein A-I; Cells, Cultured; Clofibrate; Clofibric Acid; Dimerization; Female; Fenofibrate; Fibric Acids; Fibrinogen; Gemfibrozil; Gene Expression Regulation; Genes, Reporter; Hypolipidemic Agents; Liver; Macaca fascicularis; Male; Peroxisome Proliferators; Plasminogen Activator Inhibitor 1; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Transcription Factors; Transcriptional Activation; Tretinoin	1998
Induction of lauric acid hydroxylase activity in catfish and bluegill by peroxisome proliferating agents. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1998, Volume: 121, Issue:1-3 Topics: Animals; Clofibrate; Clofibric Acid; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Fibric Acids; Ictaluridae; Kidney; Liver; Male; Mixed Function Oxygenases; Perciformes; Peroxisome Proliferators; Rats; Species Specificity	1998
Fibrates suppress fibrinogen gene expression in rodents via activation of the peroxisome proliferator-activated receptor-alpha. Blood, 1999, May-01, Volume: 93, Issue:9 Topics: Animals; Cells, Cultured; Clofibrate; Clofibric Acid; DNA-Binding Proteins; Fenofibrate; Fibric Acids; Fibrinogen; Gene Expression Regulation; Hypolipidemic Agents; Kinetics; Liver; Male; Mice; Mice, Knockout; Peroxisome Proliferators; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcription Factors; Transcription, Genetic; Triglycerides	1999
The effect of peroxisome proliferators on mitochondrial bioenergetics. Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 48, Issue:1 Topics: Animals; Bezafibrate; Calcium; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Energy Metabolism; Fenofibrate; Fibric Acids; Gemfibrozil; Intracellular Membranes; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Oxygen; Permeability; Peroxisome Proliferators; Pyrimidines; Rats; Rats, Sprague-Dawley; Trichloroethylene	1999
Rapid determination of rat hepatocyte mRNA induction potential using oligonucleotide probes for CYP1A1, 1A2, 3A and 4A1. Xenobiotica; the fate of foreign compounds in biological systems, 2000, Volume: 30, Issue:5 Topics: Analysis of Variance; Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Clofibrate; Clofibric Acid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Female; Fibric Acids; Genetic Techniques; Glucocorticoids; Humans; Liver; Mixed Function Oxygenases; Nucleic Acid Hybridization; Oligonucleotides, Antisense; Oxidoreductases, N-Demethylating; Peroxisome Proliferators; Protein Isoforms; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors	2000
Synergistic effect of 4-hydroxynonenal and PPAR ligands in controlling human leukemic cell growth and differentiation. Free radical biology & medicine, 2002, Feb-01, Volume: 32, Issue:3 Topics: Aldehydes; Cell Differentiation; Cell Division; Chromans; Clofibrate; Clofibric Acid; Drug Synergism; Fibric Acids; HL-60 Cells; Humans; Ligands; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; U937 Cells	2002
Cell-specific toxicity of fibrates in human embryonal rhabdomyosarcoma cells. Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 367, Issue:3 Topics: Bezafibrate; Clofibrate; Clofibric Acid; Disease Models, Animal; Drug Synergism; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypolipidemic Agents; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Rhabdomyosarcoma, Embryonal; RNA, Messenger; Simvastatin; Time Factors; Transcription Factors; Tumor Cells, Cultured	2003
Peroxisome proliferator-activated receptor ligands affect growth-related gene expression in human leukemic cells. The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:3 Topics: Antineoplastic Agents; Cell Cycle; Cell Division; Chromans; Clofibrate; Clofibric Acid; Fibric Acids; Gene Expression; HL-60 Cells; Humans; Ligands; Oncogenes; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone	2003
Characterization of the species-specificity of peroxisome proliferators in rat and human hepatocytes. Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 78, Issue:2 Topics: Acyl-CoA Oxidase; Animals; Carnitine Acyltransferases; Catalase; Cell Line, Tumor; Cell Proliferation; Cell Survival; Clofibrate; Clofibric Acid; Fibric Acids; Gene Expression Regulation; Hepatocytes; Humans; Male; Peroxisome Proliferator-Activated Receptors; Peroxisome Proliferators; Promoter Regions, Genetic; Pyrimidines; Rats; Rats, Wistar; Response Elements; Species Specificity; Transfection	2004
PPARalpha agonists stimulate progastrin production in human colorectal carcinoma cells. Regulatory peptides, 2004, Aug-15, Volume: 120, Issue:1-3 Topics: Bezafibrate; Cell Proliferation; Clofibrate; Clofibric Acid; Colorectal Neoplasms; Fenofibrate; Fibric Acids; Gastrins; Gemfibrozil; Humans; Hypolipidemic Agents; Ligands; Peroxisome Proliferator-Activated Receptors; Protein Precursors; Pyrimidines; Radioimmunoassay; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Vasodilator Agents	2004