Page last updated: 2024-09-05

cinnamophilin and guaiacol

cinnamophilin has been researched along with guaiacol in 12 studies

*Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747) [MeSH]

*Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747) [MeSH]

Compound Research Comparison

Studies
(cinnamophilin)
Trials
(cinnamophilin)
Recent Studies (post-2010)
(cinnamophilin)
Studies
(guaiacol)
Trials
(guaiacol)
Recent Studies (post-2010) (guaiacol)
13051,75825647

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (25.00)18.2507
2000's4 (33.33)29.6817
2010's4 (33.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Chang, H; Cheng, HT1
Teng, CM; Wu, TS; Yu, SM1
Ko, FN; Lee, JY; Teng, CM; Wu, TS; Yu, SM1
Cheng, YW; Hsiao, G; Lam, KK; Lee, YM; Sheu, JR; Teng, CM; Wu, TS; Yen, MH1
Chang, GL; Chen, HY; Chen, TY; Hsu, YS; Hu, YL; Lee, EJ; Lee, MY; Wu, TS1
Chang, GJ; Chen, WP; Kuo, CM; Su, MJ; Wu, TS1
Chen, HY; Chen, TY; Chen, YH; Chuang, IC; Hung, YC; Lee, EJ; Lee, MY; Wu, TS; Yu, SC1
Chen, TY; Huang, CC; Huang, SY; Lee, AC; Lee, EJ; Tai, SH; Wu, TS1
Bhardwaj, A1
Chen, CY; Cheng, MJ; Wang, CJ; Yeh, YT1
Hsiao, G; Hsieh, MS; Jayakumar, T; Lin, KH; Lu, YC; Sheu, JR; Wu, TS1
Huang, BH; Huang, SY; Hung, CC; Lee, TE; Teng, YN; Wu, IT; Wu, TS1

Other Studies

12 other study(ies) available for cinnamophilin and guaiacol

ArticleYear
Reduction of reperfusion injury in rat skeletal muscle following administration of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor.
    The Thoracic and cardiovascular surgeon, 1995, Volume: 43, Issue:2

    Topics: Animals; Catalase; Female; Guaiacol; Hindlimb; Ischemia; Lignans; Muscle, Skeletal; Random Allocation; Rats; Rats, Wistar; Receptors, Thromboxane; Reperfusion Injury; Superoxide Dismutase; Thromboxane-A Synthase; Tissue Survival

1995
Pharmacological characterization of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor.
    British journal of pharmacology, 1994, Volume: 111, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Aorta; Arachidonic Acid; Bleeding Time; Blood Platelets; Bronchoconstriction; Calcium; Cyclic AMP; Female; Guaiacol; Guinea Pigs; Humans; Lignans; Male; Mice; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Wistar; Receptors, Thromboxane; Sheep; Tail; Thromboxane A2; Thromboxane-A Synthase; Trachea; Vasoconstrictor Agents

1994
Cinnamophilin, a novel thromboxane A2 receptor antagonist, isolated from Cinnamomum philippinense.
    European journal of pharmacology, 1994, Apr-11, Volume: 256, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Female; Guaiacol; Guinea Pigs; In Vitro Techniques; Lignans; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Plants, Medicinal; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Rabbits; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Thromboxane; Taiwan; Thromboxane A2

1994
Cinnamophilin as a novel antiperoxidative cytoprotectant and free radical scavenger.
    Biochimica et biophysica acta, 2001, Feb-16, Volume: 1525, Issue:1-2

    Topics: Animals; Aorta; Brain; Cell Line; Cell Membrane; Cryoprotective Agents; Free Radical Scavengers; Guaiacol; Humans; In Vitro Techniques; Lignans; Lipid Peroxidation; Liver; Mitochondria, Liver; NADPH Oxidases; NADPH-Ferrihemoprotein Reductase; Neutrophils; Peroxides; Rats; Rats, Inbred SHR; Rats, Wistar; Superoxides

2001
Cinnamophilin reduces oxidative damage and protects against transient focal cerebral ischemia in mice.
    Free radical biology & medicine, 2005, Aug-15, Volume: 39, Issue:4

    Topics: Animals; Antioxidants; Brain Ischemia; Cerebral Cortex; Cerebrovascular Circulation; Free Radical Scavengers; Guaiacol; Infarction, Middle Cerebral Artery; Lignans; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Time Factors

2005
Electromechanical characterization of cinnamophilin, a natural thromboxane A2 receptor antagonist with anti-arrhythmic activity, in guinea-pig heart.
    British journal of pharmacology, 2008, Volume: 153, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Calcium Channels, L-Type; Guaiacol; Guinea Pigs; Heart; Heart Conduction System; In Vitro Techniques; Lignans; Male; Papillary Muscles; Potassium Channels; Receptors, Thromboxane A2, Prostaglandin H2; Sodium Channels

2008
Therapeutic window for cinnamophilin following oxygen-glucose deprivation and transient focal cerebral ischemia.
    Experimental neurology, 2009, Volume: 217, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Benzothiazoles; Body Weight; Cell Line, Transformed; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Guaiacol; Hippocampus; Hypoxia; Interleukin-6; Ischemic Attack, Transient; Lignans; Lipid Peroxidation; Microglia; Nitrates; Nitrites; Organ Culture Techniques; Peroxidase; Phenethylamines; Polysaccharides; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sulfonic Acids; Time Factors; Tumor Necrosis Factor-alpha

2009
Cinnamophilin offers prolonged neuroprotection against gray and white matter damage and improves functional and electrophysiological outcomes after transient focal cerebral ischemia.
    Critical care medicine, 2011, Volume: 39, Issue:5

    Topics: Animals; Antioxidants; Behavior, Animal; Body Weight; Brain; Cerebral Cortex; Confidence Intervals; Disease Models, Animal; Electrophysiology; Evoked Potentials, Somatosensory; Guaiacol; Ischemic Attack, Transient; Lignans; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neuroprotective Agents; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Statistics, Nonparametric; Survival Rate

2011
Experimental studies on ischemic neuroprotection: criteria for translational significance.
    Critical care medicine, 2011, Volume: 39, Issue:5

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Disease Progression; Electrophysiology; Evoked Potentials, Somatosensory; Guaiacol; Lignans; Neuroprotective Agents; Prospective Studies; Rats; Stroke; Treatment Outcome

2011
A new 3,4-dihydronaphthalen-1(2H)-one from the leaves of Cinnamomum philippinense.
    Natural product research, 2012, Volume: 26, Issue:15

    Topics: Cinnamomum; Guaiacol; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Leaves

2012
Cinnamophilin isolated from Cinnamomum philippinense protects against collagen degradation in human chondrocytes.
    Phytotherapy research : PTR, 2013, Volume: 27, Issue:6

    Topics: Cell Line; Chondrocytes; Cinnamomum; Collagen; Guaiacol; Humans; I-kappa B Proteins; Interleukin-1beta; Lignans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Mitogen-Activated Protein Kinases; NF-KappaB Inhibitor alpha; Phosphorylation; Proto-Oncogene Proteins c-jun; Signal Transduction

2013
Cinnamophilin overcomes cancer multi-drug resistance via allosterically modulating human P-glycoprotein on both drug binding sites and ATPase binding sites.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 144

    Topics: Adenosine Triphosphatases; Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Cell Cycle; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Guaiacol; Humans; Lignans; Molecular Docking Simulation; Rhodamine 123; Verapamil

2021