cinanserin has been researched along with dimoxamine* in 1 studies
1 other study(ies) available for cinanserin and dimoxamine
Article | Year |
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Comparison of the effects of R-(-)-2-amino-1-(2,5-dimethoxy-4-methylphenyl) propane (DOM), r-(-)-2-amino-1-(2,5-dimethoxy-4-methylphenyl) butane (BL-3912A) and 5-hydroxytryptamine on non-innervated vascular smooth muscle.
Isolated strips of sheep umbilical arteries contracted in the presence of R-(-)-2-amino-1-(2,5-dimethoxy-4-methylphenyl) butane (BL3912A). These contractions faded over an hour period and at this time BL3912A antagonized contractions to R-(-)-DOM, 5-hydroxytryptamine (5-HT) but not to angiotensin. The initial contraction produced by BL3912A was antagonized by cinanserin, a 5-HT antagonist. These experiments indicate that BL3912A can be classified as a partial agonist of 5-HT receptors in sheep umbilical arteries. Topics: Amphetamines; Angiotensin II; Animals; Blood Vessels; Cinanserin; DOM 2,5-Dimethoxy-4-Methylamphetamine; Female; Muscle Contraction; Muscle, Smooth; Pregnancy; Serotonin; Sheep; Umbilical Cord | 1976 |