cimetidine and pyrimidinones

cimetidine has been researched along with pyrimidinones in 27 studies

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	20 (74.07)	18.7374
1990's	6 (22.22)	18.2507
2000's	1 (3.70)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gyires, K; Hermecz, I; Kapui, Z; Sipos, J; Vasvári-Debreczy, L	1
Bach, FW; Bang, P; Knigge, U; Matzen, S; Warberg, J	1
Blaskó, G; Hermecz, I; Kapui, Z; Rózsa, I; Szécsi, T	1
Batzri, S; Thompson, WF; Toles, R	1
Langman, MJ	1
Bodéré, H; Emami, S; Gespach, C	1
Araujo, OE; Flowers, FP; Nieves, CH	1
Emami, S; Gespach, C	1
Knigge, U; Matzen, S; Warberg, J	2
Gugler, R; Jensen, JC	1
Eden, RJ; Owen, DA; Raval, P; Wright, A	1
Dracott, BN; Fallowfield, C; Milliner, KJ; Vickers, MR	1
Daly, MJ; Humphray, JM; Stables, R	1
Bertaccini, G; Coruzzi, G; Fesani, F; Medici, D; Poli, E	1
Batzri, S; Harmon, JW; Toles, R	1
Brozinsky, S; Hogan, DL; Isenberg, JI; Richardson, CT	1
Dent, JG; Leonard, TB	1
Postius, S; Szelenyi, I	1
Badger, AM; Poste, G; Young, J	1
Bertaccini, G; Cheret, AM; Lewin, MJ; Scarpignato, C	1
Fujihara, A; Kamato, T; Miyata, K; Nishida, A; Takeda, M; Yuki, H	1
Hough, LB; Mischler, SA; Nalwalk, JW; Thoburn, KK	1
Ikarashi, Y; Kawano, O; Misaki, N; Ohba, S; Uchida, M	1
Bach, FW; Kjaer, A; Knigge, U; Madsen, EL; Søe-Jensen, P; Warberg, J	1
Corbel, S; Dy, M	1
Laboy, L; LeBel, M; Wilner, K	1

Reviews

1 review(s) available for cimetidine and pyrimidinones

Article	Year
Antihistamines. International journal of dermatology, 1986, Volume: 25, Issue:4 Topics: Animals; Astemizole; Benzhydryl Compounds; Benzimidazoles; Child; Child, Preschool; Cimetidine; Drug Synergism; Guanidines; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Infant; Infant, Newborn; Kinetics; Pyrimidinones; Ranitidine; Terfenadine	1986

Trials

2 trial(s) available for cimetidine and pyrimidinones

Article	Year
Effect of a new potent H2-receptor antagonist on meal-stimulated gastric acid secretion and serum gastrin concentration in duodenal ulcer patients. Digestive diseases and sciences, 1984, Volume: 29, Issue:2 Topics: Adult; Aged; Cimetidine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Duodenal Ulcer; Eating; Female; Gastric Acid; Gastrins; Histamine H2 Antagonists; Humans; Male; Middle Aged; Pyrimidinones	1984
The effects of cimetidine and antacid on the pharmacokinetic profile of sildenafil citrate in healthy male volunteers. British journal of clinical pharmacology, 2002, Volume: 53 Suppl 1 Topics: Adult; Aluminum Hydroxide; Antacids; Anti-Ulcer Agents; Area Under Curve; Cimetidine; Cross-Over Studies; Drug Combinations; Half-Life; Humans; Magnesium Hydroxide; Male; Middle Aged; Phosphodiesterase Inhibitors; Piperazines; Purines; Pyrimidinones; Sildenafil Citrate; Sulfones	2002

Article

Year

Effect of a new potent H2-receptor antagonist on meal-stimulated gastric acid secretion and serum gastrin concentration in duodenal ulcer patients.

Digestive diseases and sciences, 1984, Volume: 29, Issue:2

Topics: Adult; Aged; Cimetidine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Duodenal Ulcer; Eating; Female; Gastric Acid; Gastrins; Histamine H2 Antagonists; Humans; Male; Middle Aged; Pyrimidinones

1984

The effects of cimetidine and antacid on the pharmacokinetic profile of sildenafil citrate in healthy male volunteers.

British journal of clinical pharmacology, 2002, Volume: 53 Suppl 1

Topics: Adult; Aluminum Hydroxide; Antacids; Anti-Ulcer Agents; Area Under Curve; Cimetidine; Cross-Over Studies; Drug Combinations; Half-Life; Humans; Magnesium Hydroxide; Male; Middle Aged; Phosphodiesterase Inhibitors; Piperazines; Purines; Pyrimidinones; Sildenafil Citrate; Sulfones

2002

Other Studies

24 other study(ies) available for cimetidine and pyrimidinones

Article	Year
Synthesis and gastroprotective activity of 4H-pyrido[1,2-a]pyrimidin-4-ones. Acta physiologica Hungarica, 1992, Volume: 80, Issue:1-4 Topics: Animals; Anti-Ulcer Agents; Atropine; Cimetidine; Decision Trees; Ethanol; Indomethacin; Pyrimidinones; Rats; Stomach Ulcer; Structure-Activity Relationship	1992
Involvement of histaminergic neurons in the stress-induced release of pro-opiomelanocortin-derived peptides in rats. Acta endocrinologica, 1989, Volume: 120, Issue:4 Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; beta-Lipotropin; Chromatography, Gel; Cimetidine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Pyrilamine; Pyrimidinones; Rats; Rats, Inbred Strains; Stress, Physiological	1989
Synthesis of prostacyclin and thromboxane A2 by rat gastric mucosa. Comparison of 1,6-dimethyl-4-oxo-1,6,7,8,9,9a-hexahydro-4H-pyrido (1,1-a)-pyrimidine-3-carboxamide and cimetidine. Arzneimittel-Forschung, 1989, Volume: 39, Issue:6 Topics: Animals; Anti-Ulcer Agents; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Epoprostenol; Gastric Mucosa; Indomethacin; Intramolecular Oxidoreductases; Isomerases; Male; Pyrimidinones; Rats; Rats, Inbred Strains; Thromboxane A2; Thromboxane-A Synthase	1989
Distortion of H2-antagonist equilibrium constants by uptake in rabbit gastric mucosal cells. Pharmacology, 1985, Volume: 30, Issue:4 Topics: Aminopyrine; Animals; Cimetidine; Cyclic AMP; Dimaprit; Gastric Acid; Gastric Mucosa; Guanidines; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Pyrimidinones; Rabbits; Radioisotopes; Rubidium; Thiadiazoles; Thiourea	1985
Antisecretory drugs and gastric cancer. British medical journal (Clinical research ed.), 1985, Jun-22, Volume: 290, Issue:6485 Topics: Aged; Cimetidine; Gastric Acid; Histamine H2 Antagonists; Humans; Middle Aged; Nitroso Compounds; Pyrimidinones; Ranitidine; Stomach Neoplasms	1985
Selective disappearance of histamine H2-receptor activity in the human gastric cancer cell line HGT-1 after short-term or chronic treatment by histamine or its H2-antagonists. Agents and actions, 1985, Volume: 16, Issue:3-4 Topics: Cell Line; Cimetidine; Histamine; Histamine H2 Antagonists; Humans; Pyrimidinones; Receptors, Histamine; Receptors, Histamine H2; Stomach Neoplasms; Vasoactive Intestinal Peptide	1985
Pharmacology of histamine H2 receptor antagonists in the human gastric cancer cell line HGT-1. Structure-activity relationship of isocytosine-furan and imidazole derivatives related to cimetidine. Biochemical pharmacology, 1986, Jun-01, Volume: 35, Issue:11 Topics: Cell Line; Cimetidine; Cyclic AMP; Histamine; Histamine H2 Antagonists; Humans; Kinetics; Pyrimidinones; Receptors, Cell Surface; Receptors, Histamine; Receptors, Histamine H2; Receptors, Vasoactive Intestinal Peptide; Stomach Neoplasms; Structure-Activity Relationship; Vasoactive Intestinal Peptide	1986
Histaminergic stimulation of prolactin secretion mediated via H1- or H2-receptors: dependence on routes of administration. Neuroendocrinology, 1986, Volume: 44, Issue:1 Topics: Animals; Cimetidine; Dimaprit; Histamine; Histamine H1 Antagonists; Male; Methylhistamines; Pituitary Gland, Anterior; Prolactin; Pyrilamine; Pyrimidinones; Rats; Receptors, Histamine; Thiazoles; Thiourea	1986
[Inhibition of microsomal enzyme activity of the liver by various H2 receptor antagonists]. Zeitschrift fur Gastroenterologie, 1987, Volume: 25, Issue:2 Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Cimetidine; Culture Techniques; Histamine H2 Antagonists; Imidazoles; Male; Microsomes, Liver; Oxygenases; Pyrimidinones; Ranitidine; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1987
Histamine H1-receptor antagonist activity assessed in conscious dogs. Journal of pharmacological methods, 1987, Volume: 18, Issue:2 Topics: Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Histamine H1 Antagonists; Male; Pyridines; Pyrimidinones	1987
Histaminergic mediation of the stress-induced release of prolactin in male rats. Neuroendocrinology, 1988, Volume: 47, Issue:1 Topics: Animals; Cimetidine; Ether; Histamine; Injections, Intravenous; Injections, Intraventricular; Male; Prolactin; Pyrilamine; Pyrimidinones; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Histamine; Restraint, Physical; Stress, Physiological	1988
The effects of histamine H2-receptor antagonists on PHA induced lymphocyte proliferation. Agents and actions, 1984, Volume: 15, Issue:3-4 Topics: Burimamide; Cimetidine; Histamine H2 Antagonists; Histamine Release; Humans; In Vitro Techniques; Lymphocyte Activation; Phytohemagglutinins; Pyrimidinones; Ranitidine	1984
Comparison of antisecretory potency and duration of action of the H2-receptor antagonists AH 22216, cimetidine, ranitidine and SK & F 93479 in the dog. Agents and actions, 1983, Volume: 13, Issue:2-3 Topics: Animals; Cimetidine; Dogs; Furans; Gastric Acid; Guanidines; Histamine H2 Antagonists; Male; Piperidines; Pyrimidinones; Ranitidine; Time Factors; Triazoles	1983
Negative inotropic effect of some H2-receptor antagonists on the isolated human atria. Experientia, 1983, Nov-15, Volume: 39, Issue:11 Topics: Calcium; Cimetidine; Depression, Chemical; Dose-Response Relationship, Drug; Heart Atria; Histamine H2 Antagonists; Humans; Imidazoles; Myocardial Contraction; Pyrimidinones; Verapamil	1983
Comparison of cimetidine with new H2-antagonists in rabbit and guinea pig gastric cells. European journal of pharmacology, 1983, Oct-14, Volume: 94, Issue:1-2 Topics: Aminopyrine; Animals; Cimetidine; Cyclic AMP; Gastric Acid; Gastric Mucosa; Guanidines; Guinea Pigs; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Male; Pyrimidinones; Rabbits; Thiadiazoles	1983
Effects of H2 receptor antagonists on the hepatotoxicity of various chemicals. Research communications in chemical pathology and pharmacology, 1984, Volume: 44, Issue:3 Topics: 1-Propanol; Acetaminophen; Animals; Bromobenzenes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Cimetidine; Drug Antagonism; Drug Synergism; Histamine H2 Antagonists; Imidazoles; Liver; Male; Propanols; Pyrimidinones; Ranitidine; Rats; Rats, Inbred F344	1984
The effect of different histamine H2-receptor antagonists on the gastric acid secretion of the isolated whole stomach of the mouse and on the heart rate of spontaneously beating atrium of the guinea-pig. Arzneimittel-Forschung, 1984, Volume: 34, Issue:7 Topics: Animals; Cimetidine; Gastric Acid; Gastric Mucosa; Guinea Pigs; Heart Rate; Histamine H2 Antagonists; In Vitro Techniques; Metiamide; Mice; Pyrimidinones	1984
Reversal of histamine-mediated immunosuppression by structurally diverse histamine type II (H2) receptor antagonists. International journal of immunopharmacology, 1984, Volume: 6, Issue:5 Topics: Animals; Cells, Cultured; Chemical Phenomena; Chemistry; Cimetidine; Histamine; Histamine H2 Antagonists; Immune Tolerance; Lymphocytes; Mitogens; Monocytes; Pyrimidinones; Ranitidine	1984
Inhibition of the histamine-stimulated adenylate cyclase activity of guinea pig gastric cells by the H2-receptor antagonists cimetidine, oxmetidine and SKF 93479. Pharmacology, 1984, Volume: 28, Issue:5 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cimetidine; Gastric Mucosa; Guinea Pigs; Histamine Antagonists; Histamine H2 Antagonists; Imidazoles; In Vitro Techniques; Male; Pyrimidinones	1984
Antisecretory effects of a novel and long-lasting histamine H2-receptor antagonist, YM-14471, in rats and dogs. Japanese journal of pharmacology, 1993, Volume: 63, Issue:3 Topics: Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Histamine H2 Antagonists; Infusions, Intravenous; Male; Omeprazole; Pyrimidinones; Rats; Rats, Wistar; Thiazoles	1993
Histamine-induced modulation of nociceptive responses. Pain, 1994, Volume: 58, Issue:1 Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Mesencephalon; Microinjections; Naloxone; Nociceptors; Pain Measurement; Periaqueductal Gray; Pyrimidinones; Raphe Nuclei; Rats; Rats, Sprague-Dawley	1994
Effect of the novel histamine H2-antagonist 5,6-dimethyl-2-[4-[3-(1- piperidinomethyl)phenoxy]-(z)-2-butenylamino]-4(1H)-pyrimidine dihydrochloride on histamine-induced gastric acid secretion in Heidenhain pouch dogs. Arzneimittel-Forschung, 1993, Volume: 43, Issue:8 Topics: Administration, Oral; Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Gastric Mucosa; Histamine; Histamine H2 Antagonists; Injections, Intravenous; Male; Piperidines; Pyrimidinones	1993
Insulin/hypoglycemia-induced adrenocorticotropin and beta-endorphin release: involvement of hypothalamic histaminergic neurons. Endocrinology, 1993, Volume: 132, Issue:5 Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Cetirizine; Cimetidine; Histamine; Histamine Agonists; Histamine Antagonists; Hypoglycemia; Hypothalamus; Insulin; Male; Methylhistamines; Neurons; Pyrilamine; Pyrimidinones; Rats; Rats, Wistar	1993
Evidence for bidirectional histamine transport by murine hematopoietic progenitor cells. FEBS letters, 1996, Aug-12, Volume: 391, Issue:3 Topics: Animals; Biological Transport; Calcium; Cell Line; Cetirizine; Cimetidine; Female; Hematopoietic Stem Cells; Histamine; Histamine Antagonists; Interleukin-3; Male; Mice; Mice, Inbred C57BL; Piperidines; Pyrimidinones; Sodium	1996