cimetidine and nizatidine

cimetidine has been researched along with nizatidine in 81 studies

Research

Studies (81)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (16.05)	18.7374
1990's	40 (49.38)	18.2507
2000's	18 (22.22)	29.6817
2010's	10 (12.35)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Biagini, GA; Chandramohanadas, R; Darling, C; DeGrado, WF; Diamond, SL; Fisher, N; Greenbaum, DC; Jing, H; Jo, H; Lucumi, E; Napper, AD; Shone, AE; Ward, SA	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Blago, MR; Girmania, P; Laguzzi, E; Sitar, G	1
Elezoglou, A; Kounenis, G; Koutsoviti-Papadopoulou, M; Voutsas, A	1
Bachmann, K; Jauregui, L; Levine, L; Martin, M; Mauro, LS; Sullivan, TJ	1
Michocki, RJ; Richardson, JP	1
Chia, SC; Chong, YY; Fock, KM; Yap, CK	1
Fox, MJ; Frank, WO; Nambi, P; Palmer, RH; Wetherington, JD	1
Baraona, E; Caballería, J; Deulofeu, R; Hernández-Muñoz, R; Lieber, CS; Rodés, J	1
Nwokolo, CU; Pounder, RE; Sawyerr, AM; Smith, JT	1
Guram, M; Holt, S; Howden, CW	1
Kurimoto, T; Omata, T; Ozeki, M; Segawa, Y; Tagashira, E; Takei, M; Tsuzuike, N; Yamaji, Y	1
Abe, T; Aita, H; Chaki, K; Kurimoto, T; Morita, H; Omata, T; Segawa, Y; Ueki, S; Yamaji, Y; Yoshida, A	1
Enriz, RD; Jáuregui, EA	1
Best, KL; Goode, RL; Hirsch, KS; Lin, TM; Neubauer, BL; Pioch, RP; Probst, KS; Shaar, CJ; Tinsley, FC	1
Fagan, TC; Fennerty, B; Lipsy, RJ	1
Gavey, C; Nwokolo, CU; Pounder, RE; Sawyerr, A; Smith, JT	1
Cherner, JA; Cloud, ML; Latz, JE; Offen, WW	1
Dammann, HG; Dreyer, M; Gottlieb, WR; Müller, P; Simon, B; Wolf, N	1
Chapman, JM; Kosh, JW; Sowell, JW	1
Gardner, JD; Jensen, RT; Maton, PN	1
Evans, DC; Lin, TM; Pioch, RP; Warrick, MW	1
Arvela, P; Klotz, U; Pasanen, M; Pelkonen, O; Sotaniemi, E	1
Dammann, HG; Dreyer, M; Gottlieb, WR; Keohane, P; Müller, P; Simon, B; Walter, TA	1
Gavaler, JS; Heyl, A; Susen, B; Van Thiel, DH	1
Hammond, JB; Offen, WW	1
Matsumoto, C; McMahon, FG; Offen, WW; Regel, G; Ryan, J; Vargas, R	1
Dicke, JM; Henderson, GI; Johnson, RF; Kuehl, TJ; Schenker, S	1
Forsyth, DR; Jayasinghe, KS; Roberts, CJ	1
Harada, M; Kaneko, H; Kotera, H; Mitsuma, T; Nagai, H; Uchida, K	1
Castell, DO; Just, RJ; Lagerström, PO; Leite, LP	1
Bosron, WF; Davis, GJ; Hurley, TD; Kedishvili, NY; Li, TK; Peggs, CF; Stone, CL; Thomasson, HR	1
Bachmann, KA; Jauregui, L; Levine, L; Miller, K; Reese, J; Sullivan, TJ	1
Aoki, T; Fukuda, S; Hanyu, N; Hashimoto, Y; Iikura, M; Ohira, Y	1
Howden, CW; Kelman, AW; McGill, PE; Milligan, PA; Whiting, B	1
Bachmann, KA; Jauregui, L; Levine, L; Miller, K; Reese, JH; Sullivan, TJ	1
Nakamura, H; Sano, H; Sugiyama, Y; Yamazaki, M	1
Gugler, R	1
Ring, BJ; Wrighton, SA	1
Aita, H; Chaki, K; Hori, Y; Itoh, Z; Morita, H; Seiki, M; Tagashira, E; Ueki, S; Yoneta, T	1
Notar-Francesco, V; Raffaniello, RD; Raufman, JP; Straus, EW	1
Kriegler, A; van der Walt, BJ; van Zyl, JM	1
Jacyna, MR; Levi, AJ; Miller, RJ; O'Reilly, S; Ross, J; Ryder, SD	1
Iga, T; Kawakami, J; Sawada, Y; Shimokawa, M; Yamamoto, K	1
Csepregi, A; Nemesánszky, E	1
Berstad, A; Hatlebakk, JG	1
Iga, T; Matsuo, H; Sawada, Y; Takedomi, S; Yamamoto, K; Yamano, K	1
Chase, SL; Peterson, AM; Wordell, CJ	1
Aster, RH; Curtis, BR; Gentilini, G	1
Berlin, JA; Burnham, D; Weinberg, DS	1
Chan, CK; Cheung, E; Ching, TY; Chu, KM; Kong, Y; Kou, M; Kumana, CR; Lam, SK; Seto, WH	1
Chang, BL; Ho, C; Hsu, SY; Huang, HM; Shaw, CY	1
Itoh, Z; Matsunaga, Y; Tamaki, H; Ueki, S; Yoneta, T	1
Davis, SS; He, P; Illum, L	1
Etchason, J; Fultz, SL; Good, CB; Trilli, L	1
Furuta, S; Kamada, E; Kawabata, Y; Sano, H; Shinozaki, Y; Sugimoto, T; Suzuki, T	1
Chen, SH; Ho, YH; Ko, HS; Wu, HL; Wu, SM	2
Basit, AW; Lacey, LF; Newton, JM	1
Sanders, TA; Taylor, D; Werneke, U	1
Itoh, H; Naito, T; Takeyama, M	1
Esplugues, JV; Martí-Cabrera, M; Ponce, J	1
Darwish, IA; Hassan, AI; Hussein, SA; Mahmoud, AM	1
Ashiru, DA; Basit, AW; Patel, R	1
Chang, YX; Du, LM; Guo, M; Li, CF; Qiu, YQ	1
Eberlein, B; Gebhardt, E; Gilbertz, KP; Placzek, M; Przybilla, B	1
Ouyang, D; Wan, J; Wang, R; Yin, H; Zheng, Y	1
Diogo, HP; Moura Ramos, JJ; Viciosa, MT	1

Reviews

10 review(s) available for cimetidine and nizatidine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The clinical use of histamine-2 receptor antagonists. Maryland medical journal (Baltimore, Md. : 1985), 1992, Volume: 41, Issue:5 Topics: Cimetidine; Drug Evaluation; Famotidine; Gastroesophageal Reflux; Humans; Nizatidine; Peptic Ulcer; Ranitidine; Recurrence; Time Factors	1992
Clinical review of histamine2 receptor antagonists. Archives of internal medicine, 1990, Volume: 150, Issue:4 Topics: Cimetidine; Drug Interactions; Duodenal Ulcer; Famotidine; Histamine H2 Antagonists; Humans; Nizatidine; Ranitidine; Stomach Ulcer; Thiazoles	1990
Recent advances in the management of gastric acid hypersecretion in patients with Zollinger-Ellison syndrome. Gastroenterology clinics of North America, 1989, Volume: 18, Issue:4 Topics: Cimetidine; Famotidine; Gastric Acid; Histamine H2 Antagonists; Humans; Nizatidine; Omeprazole; Parasympatholytics; Ranitidine; Thiazoles; Zollinger-Ellison Syndrome	1989
H2-antagonists and alcohol. Do they interact? Drug safety, 1994, Volume: 10, Issue:4 Topics: Alcohol Dehydrogenase; Animals; Cimetidine; Drug Interactions; Ethanol; Famotidine; Histamine H2 Antagonists; Humans; Nizatidine; Ranitidine; Rats	1994
[H2-receptor antagonists and alcohol: clinical significance]. Orvosi hetilap, 1996, Jun-16, Volume: 137, Issue:24 Topics: Cimetidine; Clinical Medicine; Drug Interactions; Ethanol; Famotidine; Gastric Mucosa; Histamine H2 Antagonists; Humans; Liver; Nizatidine; Piperidines; Ranitidine	1996
Pharmacokinetic optimisation in the treatment of gastro-oesophageal reflux disease. Clinical pharmacokinetics, 1996, Volume: 31, Issue:5 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antacids; Benzimidazoles; Cimetidine; Cisapride; Domperidone; Famotidine; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Lansoprazole; Metoclopramide; Nizatidine; Omeprazole; Pantoprazole; Piperidines; Proton Pump Inhibitors; Ranitidine; Sucralfate; Sulfoxides	1996
Effect of histamine-2 receptor antagonists on blood alcohol levels: a meta-analysis. Journal of general internal medicine, 1998, Volume: 13, Issue:9 Topics: Cimetidine; Ethanol; Famotidine; Histamine H2 Antagonists; Humans; Nizatidine; Ranitidine	1998
Options for pharmacological management of obesity in patients treated with atypical antipsychotics. International clinical psychopharmacology, 2002, Volume: 17, Issue:4 Topics: Amantadine; Antipsychotic Agents; Cimetidine; Cyclobutanes; Fluoxetine; Fructose; Humans; Lactones; Metformin; Nizatidine; Obesity; Orlistat; Topiramate; Weight Gain	2002
[Safety of proton pump inhibitors]. Medicina clinica, 2006, Nov-25, Volume: 127, Issue:20 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Adult; Age Factors; Aged; Animals; Anti-Ulcer Agents; Cimetidine; Enzyme Inhibitors; Famotidine; Female; Fetus; Histamine H2 Antagonists; Humans; Lactation; Lansoprazole; Meta-Analysis as Topic; Nizatidine; Omeprazole; Pantoprazole; Pregnancy; Proton Pump Inhibitors; Proton-Translocating ATPases; Rabeprazole; Ranitidine; Safety; Time Factors	2006

Trials

14 trial(s) available for cimetidine and nizatidine

Article	Year
Role of H2-receptor antagonists in the treatment of duodenitis. The Tokai journal of experimental and clinical medicine, 1992, Volume: 17, Issue:2 Topics: Cimetidine; Duodenitis; Female; Histamine H2 Antagonists; Humans; Male; Nizatidine; Ranitidine	1992
Nizatidine versus cimetidine in the treatment of duodenal ulcers. Annals of the Academy of Medicine, Singapore, 1991, Volume: 20, Issue:2 Topics: Adult; Aged; Cimetidine; Duodenal Ulcer; Endoscopy, Gastrointestinal; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Nizatidine; Thiazoles; Wound Healing	1991
Rebound intragastric hyperacidity after abrupt withdrawal of histamine H2 receptor blockade. Gut, 1991, Volume: 32, Issue:12 Topics: Adult; Cimetidine; Drug Administration Schedule; Drug Tolerance; Famotidine; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Gastrins; Histamine H2 Antagonists; Humans; Male; Nizatidine; Ranitidine; Stomach	1991
Comparison of nizatidine and cimetidine as once-nightly treatment of acute duodenal ulcer. Nizatidine Multicenter Duodenal Ulcer Study Group. The American journal of gastroenterology, 1989, Volume: 84, Issue:7 Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Cimetidine; Creatinine; Double-Blind Method; Drug Administration Schedule; Duodenal Ulcer; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Multicenter Studies as Topic; Nizatidine; Patient Compliance; Random Allocation; Smoking; Thiazoles	1989
[Inhibition of 24-hour acidity by nizatidine]. Fortschritte der Medizin, 1989, May-10, Volume: 107, Issue:14 Topics: Cimetidine; Circadian Rhythm; Clinical Trials as Topic; Double-Blind Method; Famotidine; Gastric Acid; Gastric Acidity Determination; Histamine H2 Antagonists; Humans; Nizatidine; Random Allocation; Ranitidine; Thiazoles	1989
Nocturnal acid suppression with a new H2 receptor antagonist--nizatidine. Hepato-gastroenterology, 1986, Volume: 33, Issue:5 Topics: Adult; Cimetidine; Drug Evaluation; Gastric Acid; Gastric Acidity Determination; Histamine H2 Antagonists; Humans; Male; Nizatidine; Random Allocation; Ranitidine; Thiazoles; Time Factors	1986
An evaluation of the anti-androgen effects associated with H2 antagonist therapy. Scandinavian journal of gastroenterology. Supplement, 1987, Volume: 136 Topics: Adolescent; Adult; Cimetidine; Histamine H2 Antagonists; Humans; Hypothalamo-Hypophyseal System; Male; Nizatidine; Pituitary Hormones, Anterior; Sperm Count; Testis; Testosterone; Thiazoles; Thyroxine	1987
Effect of nizatidine and cimetidine on betazole-stimulated gastric secretion of normal subjects: comparison of effects on acid, water, and pepsin. The American journal of gastroenterology, 1988, Volume: 83, Issue:1 Topics: Adult; Aged; Betazole; Body Water; Cimetidine; Dose-Response Relationship, Drug; Double-Blind Method; Gastric Acid; Gastric Juice; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Nizatidine; Pepsin A; Pyrazoles; Random Allocation; Thiazoles	1988
Pharmacokinetics and pharmacodynamics of oral nizatidine. Journal of clinical pharmacology, 1988, Volume: 28, Issue:1 Topics: Administration, Oral; Adult; Cimetidine; Dietary Proteins; Gastric Acid; Gastrins; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Male; Nizatidine; Thiazoles; Time Factors	1988
Do nizatidine and cimetidine interact with ibuprofen? European journal of clinical pharmacology, 1988, Volume: 35, Issue:1 Topics: Adult; Cimetidine; Double-Blind Method; Drug Interactions; Half-Life; Histamine H2 Antagonists; Humans; Ibuprofen; Male; Nizatidine; Thiazoles	1988
The consequences of H2 receptor antagonist--piroxicam coadministration in patients with joint disorders. European journal of clinical pharmacology, 1993, Volume: 45, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Arthritis; Cimetidine; Drug Interactions; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Nizatidine; Peptic Ulcer; Piroxicam	1993
Short report: a comparative study of the interaction between antacid and H2-receptor antagonists. Alimentary pharmacology & therapeutics, 1994, Volume: 8, Issue:1 Topics: Adult; Antacids; Biological Availability; Chromatography, High Pressure Liquid; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Famotidine; Histamine H2 Antagonists; Humans; Male; Nizatidine	1994
Histamine-2 receptor antagonists do not alter serum ethanol levels in fed, nonalcoholic men. Annals of internal medicine, 1993, Apr-01, Volume: 118, Issue:7 Topics: Adult; Asian People; Cimetidine; Drug Interactions; Ethanol; Famotidine; Histamine H2 Antagonists; Humans; Male; Nizatidine; Prospective Studies; Ranitidine	1993
Effects of histamine H(2)-receptor antagonists on human plasma levels of calcitonin gene-related peptide, substance P and vasoactive intestinal peptide. The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:11 Topics: Adult; Calcitonin Gene-Related Peptide; Cimetidine; Famotidine; Histamine H2 Antagonists; Humans; Male; Nizatidine; Ranitidine; Substance P; Time Factors; Vasoactive Intestinal Peptide	2002

Other Studies

57 other study(ies) available for cimetidine and nizatidine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9 Topics: Animals; Antimalarials; Drug Resistance, Multiple; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Comparative study of the H2-receptor antagonists cimetidine, ranitidine, famotidine and nizatidine on the rabbit stomach fundus and sigmoid colon. Journal of pharmacobio-dynamics, 1992, Volume: 15, Issue:10 Topics: Acetylcholine; Animals; Cimetidine; Colon, Sigmoid; Famotidine; Female; Gastric Fundus; Histamine H2 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nizatidine; Rabbits; Ranitidine	1992
Comparative investigation of the influence of nizatidine, ranitidine, and cimetidine on the steady-state pharmacokinetics of theophylline in COPD patients. Journal of clinical pharmacology, 1992, Volume: 32, Issue:5 Topics: Administration, Oral; Aged; Cimetidine; Delayed-Action Preparations; Humans; Lung Diseases, Obstructive; Middle Aged; Nizatidine; Ranitidine; Theophylline	1992
Effects of various concomitant medications on gastric alcohol dehydrogenase and the first-pass metabolism of ethanol. The American journal of gastroenterology, 1991, Volume: 86, Issue:12 Topics: Acetaminophen; Adult; Alcohol Dehydrogenase; Animals; Cimetidine; Ethacrynic Acid; Ethanol; Female; Histamine H2 Antagonists; Humans; In Vitro Techniques; Male; Middle Aged; Nizatidine; Propranolol; Ranitidine; Rats; Reference Values; Salicylates; Salicylic Acid	1991
Effects of H2-receptor antagonists on gastric alcohol dehydrogenase activity. Digestive diseases and sciences, 1991, Volume: 36, Issue:12 Topics: Alcohol Dehydrogenase; Animals; Cimetidine; Famotidine; Gastric Mucosa; Histamine H2 Antagonists; Liver; Male; Nizatidine; Ranitidine; Rats; Rats, Inbred Strains	1991
Further evidence for an interaction between alcohol and certain H2-receptor antagonists. Alcoholism, clinical and experimental research, 1991, Volume: 15, Issue:6 Topics: Adult; Alcoholic Intoxication; Cimetidine; Ethanol; Famotidine; Histamine H2 Antagonists; Humans; Male; Nizatidine; Omeprazole; Ranitidine	1991
Effects of the new anti-ulcer drug nizatidine on prostaglandins in the rat gastric mucosa. Arzneimittel-Forschung, 1991, Volume: 41, Issue:9 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cimetidine; Dinoprostone; Dose-Response Relationship, Drug; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; In Vitro Techniques; Male; Microsomes; Nizatidine; Prostaglandins; Ranitidine; Rats; Rats, Inbred Strains; Sheep	1991
Effects of successive doses of nizatidine, cimetidine and ranitidine on serum gastrin level and gastric acid secretion. Arzneimittel-Forschung, 1991, Volume: 41, Issue:9 Topics: Animals; Cimetidine; Gastric Acid; Gastrins; Male; Nizatidine; Pylorus; Ranitidine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome	1991
[Theoretical conformation study of tiotidine and nizatidine, two strong histamine H2-receptor antagonists]. Acta cientifica venezolana, 1991, Volume: 42, Issue:2 Topics: Cimetidine; Isomerism; Models, Theoretical; Molecular Conformation; Nizatidine; Receptors, Histamine H2	1991
Endocrine effects of a new histamine H2-receptor antagonist, nizatidine (LY139037), in the male rat. Toxicology and applied pharmacology, 1990, Volume: 102, Issue:2 Topics: Androgens; Animals; Cimetidine; Gastric Acid; Histamine H2 Antagonists; Hypothalamus; Male; Metribolone; Molecular Structure; Nizatidine; Orchiectomy; Organ Size; Pituitary Gland; Preoptic Area; Prolactin; Prostate; Rats; Rats, Inbred Strains; Receptors, Androgen; Seminal Vesicles; Testis; Thiazoles	1990
Tolerance during 29 days of conventional dosing with cimetidine, nizatidine, famotidine or ranitidine. Alimentary pharmacology & therapeutics, 1990, Volume: 4 Suppl 1 Topics: Adult; Cimetidine; Drug Tolerance; Famotidine; Gastric Acid; Gastrins; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Male; Nizatidine; Ranitidine	1990
A comparison of the cholinergic activity of selected H2-antagonists and sulfoxide metabolites. Pharmaceutical research, 1989, Volume: 6, Issue:8 Topics: Acetylcholine; Animals; Brain Chemistry; Cholinesterase Inhibitors; Cimetidine; Famotidine; Furans; Histamine H2 Antagonists; Ileum; Male; Mice; Nizatidine; Parasympathomimetics; Ranitidine; Structure-Activity Relationship; Sulfoxides; Thiazoles	1989
Actions of nizatidine, a selective histamine H2-receptor antagonist, on gastric acid secretion in dogs, rats and frogs. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2 Topics: Administration, Oral; Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Gastric Acid; Histamine H2 Antagonists; Infusions, Parenteral; Molecular Weight; Nizatidine; Rana catesbeiana; Rats; Tetragastrin; Thiazoles	1986
Effect of five structurally diverse H2-receptor antagonists on drug metabolism. Biochemical pharmacology, 1986, Dec-15, Volume: 35, Issue:24 Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cimetidine; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Diazepam; Famotidine; Histamine H2 Antagonists; Humans; Imidazoles; Kinetics; Male; Microsomes, Liver; Nizatidine; Oxidoreductases; Oxygenases; Pharmaceutical Preparations; Ranitidine; Rats; Rats, Inbred Strains; Thiazoles	1986
A comparative evaluation of the transport of H2-receptor antagonists by the human and baboon placenta. The American journal of the medical sciences, 1988, Volume: 295, Issue:3 Topics: Adolescent; Adult; Animals; Antipyrine; Biological Transport; Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Nizatidine; Papio; Perfusion; Placenta; Pregnancy; Ranitidine; Thiazoles	1988
New H2-blockers: does more choice help? Drug and therapeutics bulletin, 1988, Aug-22, Volume: 26, Issue:17 Topics: Anti-Ulcer Agents; Cimetidine; Famotidine; Humans; Nizatidine; Peptic Ulcer; Ranitidine; Thiazoles	1988
Nizatidine accelerates gastric emptying of a solid meal in rats. Digestive diseases and sciences, 1995, Volume: 40, Issue:9 Topics: Acetylcholine; Animals; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Gastric Emptying; Gastric Juice; Gastrins; Histamine H2 Antagonists; Male; Nizatidine; Rats; Rats, Wistar; Stimulation, Chemical	1995
Control of gastric acid with high dose H2-receptor antagonists after omeprazole failure: report of two cases. The American journal of gastroenterology, 1995, Volume: 90, Issue:10 Topics: Adult; Anti-Ulcer Agents; Cimetidine; Drug Resistance; Female; Gastric Acid; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Male; Nizatidine; Omeprazole	1995
Cimetidine inhibition of human gastric and liver alcohol dehydrogenase isoenzymes: identification of inhibitor complexes by kinetics and molecular modeling. Biochemistry, 1995, Mar-28, Volume: 34, Issue:12 Topics: Alcohol Dehydrogenase; Binding, Competitive; Cimetidine; Famotidine; Gastric Mucosa; Humans; Isoenzymes; Kinetics; Liver; Mathematics; Models, Molecular; NAD; Nizatidine; Ranitidine; Recombinant Proteins; Structure-Activity Relationship	1995
Drug interactions of H2-receptor antagonists. Scandinavian journal of gastroenterology. Supplement, 1994, Volume: 206 Topics: Adolescent; Adult; Aged; Antacids; Biological Availability; Cimetidine; Drug Interactions; Famotidine; Histamine H2 Antagonists; Humans; Middle Aged; Nizatidine; Omeprazole; Phenytoin; Ranitidine; Theophylline	1994
[Effects of various histamine H2-receptor antagonists on gastrointestinal motility and gastric emptying]. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1993, Volume: 29, Issue:4 Topics: Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Famotidine; Gastric Emptying; Gastrointestinal Motility; Histamine H2 Antagonists; Nizatidine; Piperidines; Ranitidine	1993
Carrier-mediated active transport of histamine H2 receptor antagonists, cimetidine and nizatidine, into isolated rat hepatocytes: contribution of type I system. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:3 Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Cimetidine; Dose-Response Relationship, Drug; Histamine H2 Antagonists; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Male; Metabolic Clearance Rate; Nizatidine; Rats; Rats, Sprague-Dawley	1994
Inhibition of human CYP3A catalyzed 1'-hydroxy midazolam formation by ketoconazole, nifedipine, erythromycin, cimetidine, and nizatidine. Pharmaceutical research, 1994, Volume: 11, Issue:6 Topics: Chromatography, High Pressure Liquid; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythromycin; Humans; In Vitro Techniques; Ketoconazole; Microsomes, Liver; Midazolam; Nifedipine; Nizatidine	1994
Gastroprokinetic activity of nizatidine, a new H2-receptor antagonist, and its possible mechanism of action in dogs and rats. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:1 Topics: Animals; Cholinesterase Inhibitors; Cimetidine; Digestive System; Digestive System Physiological Phenomena; Dogs; Dose-Response Relationship, Drug; Famotidine; Fasting; Gastric Acid; Gastric Emptying; Gastrointestinal Motility; Histamine H2 Antagonists; Humans; Male; Motor Activity; Nizatidine; Pylorus; Rats; Rats, Sprague-Dawley	1993
Anti-oxidant properties of H2-receptor antagonists. Effects on myeloperoxidase-catalysed reactions and hydroxyl radical generation in a ferrous-hydrogen peroxide system. Biochemical pharmacology, 1993, Jun-22, Volume: 45, Issue:12 Topics: Antioxidants; Cimetidine; Famotidine; Ferrous Compounds; Histamine H2 Antagonists; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Iron Chelating Agents; NAD; Nizatidine; Peroxidase; Ranitidine	1993
Long term acid suppressing treatment in general practice. BMJ (Clinical research ed.), 1994, Mar-26, Volume: 308, Issue:6932 Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Cimetidine; Drug Utilization; Duodenal Ulcer; England; Esophageal Diseases; Family Practice; Famotidine; Female; Gastric Acid; Humans; Long-Term Care; Male; Middle Aged; Nizatidine; Patient Satisfaction; Ranitidine	1994
Neurotoxic convulsions induced by histamine H2 receptor antagonists in mice. Toxicology and applied pharmacology, 1996, Volume: 136, Issue:2 Topics: Animals; Anticonvulsants; Brain; Cimetidine; Convulsants; Famotidine; GABA Agonists; Histamine H2 Antagonists; Injections, Intraventricular; Male; Mice; Models, Biological; Nizatidine; Ranitidine; Receptors, Histamine H2; Seizures	1996
Quantitative prediction of the interaction of midazolam and histamine H2 receptor antagonists in rats. Drug metabolism and disposition: the biological fate of chemicals, 1998, Volume: 26, Issue:4 Topics: Animals; Area Under Curve; Cimetidine; Drug Interactions; Half-Life; Histamine H2 Antagonists; Liver; Male; Metabolic Clearance Rate; Midazolam; Models, Biological; Nizatidine; Rats; Rats, Wistar	1998
Therapeutic-interchange program for oral histamine H2-receptor antagonists. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1998, Jul-01, Volume: 55, Issue:13 Topics: Cimetidine; Drug Utilization; Histamine H2 Antagonists; Hospital Bed Capacity, 500 and over; Hospitals, Teaching; Humans; Nizatidine; Pennsylvania; Pharmacy Service, Hospital	1998
An antibody from a patient with ranitidine-induced thrombocytopenia recognizes a site on glycoprotein IX that is a favored target for drug-induced antibodies. Blood, 1998, Oct-01, Volume: 92, Issue:7 Topics: Aged; Animals; Anti-Ulcer Agents; Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Reactions; Autoantibodies; Autoimmune Diseases; Blood Platelets; CHO Cells; Cimetidine; Cricetinae; Cricetulus; Epitopes; Famotidine; Female; Flow Cytometry; Histamine H2 Antagonists; Humans; Molecular Structure; Nizatidine; Platelet Glycoprotein GPIb-IX Complex; Precipitin Tests; Protein Conformation; Quinidine; Quinine; Ranitidine; Recombinant Fusion Proteins; Structure-Activity Relationship; Thrombocytopenia; Transfection	1998
Antiulcer drug prescribing in hospital successfully influenced by "immediate concurrent feedback". Clinical pharmacology and therapeutics, 1998, Volume: 64, Issue:5 Topics: Administration, Oral; Anti-Ulcer Agents; Cimetidine; Cost-Benefit Analysis; Drug Utilization; Famotidine; Feedback; Hong Kong; Hospitals, Teaching; Humans; Infusions, Intravenous; Medical Audit; Nizatidine; Omeprazole; Practice Patterns, Physicians'; Ranitidine	1998
Simultaneous high-performance liquid chromatographic analysis for famotidine, ranitidine HCl, cimetidine, and nizatidine in commercial products. Drug development and industrial pharmacy, 1999, Volume: 25, Issue:3 Topics: Algorithms; Chromatography, High Pressure Liquid; Cimetidine; Famotidine; Histamine H2 Antagonists; Nizatidine; Ranitidine; Regression Analysis; Reproducibility of Results; Solvents; Spectrophotometry, Ultraviolet	1999
Gastroprokinetic activity of nizatidine during the digestive state in the dog and rat. Arzneimittel-Forschung, 1999, Volume: 49, Issue:7 Topics: Animals; Anti-Ulcer Agents; Cimetidine; Cisapride; Digestion; Dogs; Duodenum; Famotidine; Gastric Emptying; Gastrointestinal Motility; Injections, Intravenous; Intubation, Gastrointestinal; Male; Nizatidine; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Stomach	1999
Chitosan microspheres prepared by spray drying. International journal of pharmaceutics, 1999, Sep-30, Volume: 187, Issue:1 Topics: Biocompatible Materials; Biopolymers; Calorimetry, Differential Scanning; Chitin; Chitosan; Cimetidine; Cross-Linking Reagents; Delayed-Action Preparations; Famotidine; Histamine H2 Antagonists; Microscopy, Electron, Scanning; Microspheres; Molecular Weight; Nizatidine; Particle Size; Viscosity	1999
Therapeutic substitution of cimetidine for nizatidine was not associated with an increase in healthcare utilization. The American journal of managed care, 2000, Volume: 6, Issue:10 Topics: Aged; Cimetidine; Cost Savings; Drug Costs; Duodenal Ulcer; Formularies, Hospital as Topic; Gastroesophageal Reflux; Health Services Research; Histamine H2 Antagonists; Hospitals, Veterans; Humans; Male; Middle Aged; Nizatidine; Outpatient Clinics, Hospital; Pennsylvania; Retrospective Studies; Stomach Ulcer; Therapeutic Equivalency	2000
Inhibition of drug metabolism in human liver microsomes by nizatidine, cimetidine and omeprazole. Xenobiotica; the fate of foreign compounds in biological systems, 2001, Volume: 31, Issue:1 Topics: Anti-Ulcer Agents; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoenzymes; Male; Microsomes, Liver; Nizatidine; Omeprazole; Pharmaceutical Preparations	2001
Head-column field-amplified sample stacking in capillary electrophoresis for the determination of cimetidine, famotidine, nizatidine, and ranitidine-HCl in plasma. Electrophoresis, 2001, Volume: 22, Issue:13 Topics: Buffers; Cimetidine; Electric Conductivity; Electrophoresis, Capillary; Ethylene Glycol; Famotidine; Histamine H2 Antagonists; Humans; Nizatidine; Phosphates; Ranitidine; Sensitivity and Specificity; Time Factors; Water	2001
Simultaneous determination of cimetidine, famotidine, nizatidine, and ranitidine in tablets by capillary zone electrophoresis. Electrophoresis, 2001, Volume: 22, Issue:13 Topics: Anti-Ulcer Agents; Buffers; Calibration; Cimetidine; Famotidine; Histamine H2 Antagonists; Hydrogen-Ion Concentration; Molecular Structure; Nizatidine; Phosphates; Ranitidine; Tablets; Time Factors	2001
Susceptibility of the H2-receptor antagonists cimetidine, famotidine and nizatidine, to metabolism by the gastrointestinal microflora. International journal of pharmaceutics, 2002, Apr-26, Volume: 237, Issue:1-2 Topics: Bacteria, Anaerobic; Cimetidine; Digestive System; Famotidine; Female; Histamine H2 Antagonists; Humans; Nizatidine	2002
Spectrophotometric determination of H(2)-receptor antagonists via their oxidation with cerium(IV). Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2008, Volume: 69, Issue:1 Topics: Aminobenzoates; Cerium; Cimetidine; Dosage Forms; Excipients; Famotidine; Histamine H2 Antagonists; Nizatidine; Oxidation-Reduction; Ranitidine; Reproducibility of Results; Solvents; Spectrophotometry; Time Factors	2008
Simple and universal HPLC-UV method to determine cimetidine, ranitidine, famotidine and nizatidine in urine: application to the analysis of ranitidine and its metabolites in human volunteers. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Dec-15, Volume: 860, Issue:2 Topics: Chromatography, High Pressure Liquid; Cimetidine; Famotidine; Histamine H2 Antagonists; Humans; Nizatidine; Ranitidine; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet	2007
Determination of ranitidine, nizatidine, and cimetidine by a sensitive fluorescent probe. The Analyst, 2011, Oct-21, Volume: 136, Issue:20 Topics: Bridged-Ring Compounds; Cimetidine; Fluorescent Dyes; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Imidazoles; Nizatidine; Ranitidine; Spectrometry, Fluorescence; Temperature	2011
In vitro evaluation of phototoxic properties of proton pump inhibitors, H2-receptor antagonists and statins. Acta dermato-venereologica, 2012, Volume: 92, Issue:2 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Ascorbic Acid; Cimetidine; Erythrocytes; Famotidine; Hemolysis; Histamine H2 Antagonists; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lansoprazole; Lovastatin; Nizatidine; Omeprazole; Pantoprazole; Pravastatin; Proton Pump Inhibitors; Ranitidine; Ultraviolet Rays	2012
Molecular Encapsulation of Histamine H₂-Receptor Antagonists by Cucurbit[7]Uril: An Experimental and Computational Study. Molecules (Basel, Switzerland), 2016, Sep-06, Volume: 21, Issue:9 Topics: Bridged-Ring Compounds; Cimetidine; Famotidine; Histamine H2 Antagonists; Imidazoles; Molecular Dynamics Simulation; Nizatidine	2016
The Slow Relaxation Dynamics in the Amorphous Pharmaceutical Drugs Cimetidine, Nizatidine, and Famotidine. Journal of pharmaceutical sciences, 2016, Volume: 105, Issue:12 Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Cimetidine; Famotidine; Nizatidine; Time Factors	2016