cimetidine has been researched along with metyrapone in 12 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (25.00) | 18.7374 |
1990's | 3 (25.00) | 18.2507 |
2000's | 2 (16.67) | 29.6817 |
2010's | 4 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Pratim Roy, P; Roy, K | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Bennett, BM; McDonald, BJ; St James, MJ | 1 |
Birkett, DJ; Lelo, A; Miners, JO | 1 |
Kairaluoma, M; Pasanen, M; Pelkonen, O; Sotaniemi, EA; Taskinen, T | 1 |
Hall, ST; Houston, JB; Rhodes, JC | 1 |
Margolis, S; Schwartz, MA | 1 |
Bland, TJ; Robertson, IG | 1 |
1 review(s) available for cimetidine and metyrapone
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
11 other study(ies) available for cimetidine and metyrapone
Article | Year |
---|---|
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques.
Topics: Algorithms; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Factor Analysis, Statistical; Least-Squares Analysis; Linear Models; Models, Molecular; Neural Networks, Computer; Quantitative Structure-Activity Relationship; Reproducibility of Results | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Hepatic cytochrome P-450-mediated activation of rat aortic guanylyl cyclase by glyceryl trinitrate.
Topics: Animals; Aorta; Cimetidine; Cytochrome P-450 Enzyme System; Enzyme Activation; Guanylate Cyclase; Male; Metyrapone; Microsomes, Liver; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Ranitidine; Rats; Rats, Inbred Strains | 1992 |
Mechanism of formation of 6-amino-5-(N-methylformylamino)-1-methyluracil and 3,7-dimethyluric acid from theobromine in the rat in vitro: involvement of cytochrome P-450 and a cellular thiol.
Topics: Acetylcysteine; Animals; Cimetidine; Cysteine; Cytochrome P-450 Enzyme System; Dithiothreitol; Glutathione; Kinetics; Male; Metyrapone; Microsomes, Liver; Pyridines; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Theobromine; Uracil; Uric Acid | 1990 |
Inhibitor panel studies of human hepatic and placental cytochrome P-450-associated monooxygenase activities.
Topics: Aminoglutethimide; Animals; Benzoflavones; Cimetidine; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Debrisoquin; Enzyme Inhibitors; Female; Furans; Humans; Isoenzymes; Liver; Male; Metyrapone; Oxidoreductases; Placenta; Pregnancy; Rats; Rats, Inbred Strains | 1988 |
Inhibition of antipyrine metabolite formation in rats in vivo.
Topics: Animals; Antipyrine; Benzoflavones; Cimetidine; Cytochrome P-450 Enzyme System; Male; Metyrapone; Proadifen; Rats; Rats, Inbred Strains | 1984 |
Effects of drugs and sterols on cholesterol 7 alpha-hydroxylase activity in rat liver microsomes.
Topics: Aminoglutethimide; Animals; Ascorbic Acid; Bile Acids and Salts; Cholesterol 7-alpha-Hydroxylase; Cimetidine; Kinetics; Male; Metyrapone; Microsomes, Liver; Proadifen; Rats; Rats, Inbred Strains; Steroid Hydroxylases; Sterols | 1983 |
Inhibition by SKF-525A of the aldehyde oxidase-mediated metabolism of the experimental antitumour agent acridine carboxamide.
Topics: Acridines; Acridones; Aldehyde Oxidase; Aldehyde Oxidoreductases; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cimetidine; Cytosol; Kinetics; Liver; Male; Methimazole; Metyrapone; Microsomes, Liver; NAD; Proadifen; Rats; Rats, Wistar | 1993 |